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Insightful Session with Mathew Cook, Senior Director of Sales for the UK, Ireland, and Nordics at Merck Life Science

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Mathew discussed the strategic shifts needed to make these innovations widely accessible, the key factors investors should consider in this space, and the market barriers companies face when scaling from niche treatments to broader applicati", "mainEntityOfPage": "https://intelligence.eventackle.com/blog/insightful-session-with-mathew-cook-senior-director-of-sales-for-the-uk-ireland-and-nordics-at-merck-life-science/" } </script> <meta name="generator" content="Ghost 5.87"> <link rel="alternate" type="application/rss+xml" title="Eventackle | Intelligence" href="https://intelligence.eventackle.com/rss/"> <script defer src="https://cdn.jsdelivr.net/ghost/portal@~2.37/umd/portal.min.js" data-i18n="false" data-ghost="https://intelligence.eventackle.com/" data-key="2ae95878de79678ba2185eb257" data-api="https://intelligence.eventackle.com/ghost/api/content/" crossorigin="anonymous"></script><style id="gh-members-styles">.gh-post-upgrade-cta-content, .gh-post-upgrade-cta { display: flex; flex-direction: column; 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Communications at Valiant Business Media. With a background in journalism and a doctorate in media studies, he brings a wealth of expertise to his role. </p> <p><a href="/author/muhammad-younis/">More posts</a> by Muhammad Younis.</p> </div> </div> </div> <a href="/author/muhammad-younis/" class="author-avatar"> <img class="author-profile-image" src="//www.gravatar.com/avatar/adeee9b356e454504d71ca63d21f8a0a?s&#x3D;250&amp;d&#x3D;mm&amp;r&#x3D;x" alt="Muhammad Younis" /> </a> </li> </ul> <section class="post-full-byline-meta"> <h4 class="author-name"><a href="/author/muhammad-younis/">Muhammad Younis</a></h4> <div class="byline-meta-content"> <time class="byline-meta-date" datetime="2024-09-11">11 Sep 2024</time> <span class="byline-reading-time"><span class="bull">&bull;</span> 4 min read</span> </div> </section> </section> </div> </header> <figure class="post-full-image"> <img srcset="/content/images/size/w300/2024/09/Mathew-Cook.png 300w, /content/images/size/w600/2024/09/Mathew-Cook.png 600w, /content/images/size/w1000/2024/09/Mathew-Cook.png 1000w, /content/images/size/w2000/2024/09/Mathew-Cook.png 2000w" sizes="(max-width: 800px) 400px, (max-width: 1170px) 1170px, 2000px" src="/content/images/size/w2000/2024/09/Mathew-Cook.png" alt="Insightful Session with Mathew Cook, Senior Director of Sales for the UK, Ireland, and Nordics at Merck Life Science" /> </figure> <section class="post-full-content"> <div class="post-content"> <!--kg-card-begin: html--> <style> .blog-post .blog-content a[href='https://intelligence.eventackle.com/author/muhammad-younis/'] { color: #23404d; } </style> <!--kg-card-end: html--> <p><em>In a recent interview, <strong>Mathew Cook</strong>, Senior Director Sales - UK, Ireland Nordics (Academia, Public &amp; Pharma) at Merck Life Science | CSAM, talked with </em><a href="https://intelligence.eventackle.com/author/muhammad-younis/"><strong><em>Muhammad Younis</em></strong></a><em> about the evolving landscape of advanced therapies, including cell and gene therapies. Mathew discussed the strategic shifts needed to make these innovations widely accessible, the key factors investors should consider in this space, and the market barriers companies face when scaling from niche treatments to broader applications, and the ways to overcome them. Mathew also shared insights on how companies can differentiate their offerings beyond clinical efficacy to build a sustainable business model in a competitive market.</em></p><p><strong>#LBS: In what ways do you see cell and gene therapy reshaping the future of medicine, and what strategic shifts are needed in the industry to ensure these innovations are not just breakthroughs for the few, but accessible solutions for the many?</strong></p><p><strong>Mathew Cook:</strong> Cell and gene therapy have the potential to reshape the future of medicine:</p><p>鈼廝ersonalised Medicine: These therapies enable treatments tailored to individual genetic profiles, leading to more effective and targeted interventions.</p><p>鈼廋ure/Improvements for Genetic Disorders: Gene therapies can potentially correct genetic defects at their source, offering cures for previously untreatable hereditary conditions.&nbsp;</p><p>鈼廟egenerative Medicine: Cell therapies can promote tissue repair and regeneration, transforming how we treat injuries and degenerative diseases.</p><p>鈼廋ancer Treatment: Innovations in cell therapy, such as CAR-T cell therapy, are providing new avenues for treating certain cancers, improving survival rates.</p><p>鈼廋hronic Disease Management: Gene editing technologies like CRISPR can modify genes associated with chronic diseases, potentially reducing the burden of conditions like diabetes and heart disease.</p><p>My view on the strategic shifts needed:</p><p>鈼廟egulatory Frameworks: Developing clear and adaptive regulatory pathways is essential to ensure the safety and efficacy of these therapies while promoting innovation.</p><p>鈼廙anufacturing Scalability: Investment in scalable manufacturing processes is crucial to produce therapies at a lower cost and in larger quantities, making them more accessible.</p><p>鈼廋ost Reduction Strategies: Addressing the high costs associated with cell and gene therapies through innovative pricing models, insurance coverage, and public-private partnerships can enhance accessibility.</p><p>鈼廍quitable Access Programs: Implementing programs that focus on equitable access for underserved populations can help bridge the gap between breakthrough therapies and those who need them most. So encouraging collaboration between academia, industry, and government can improve innovation and ensure that advancements are shared broadly.</p><p><strong>#LBS: With the increasing interest from investors in cell and gene therapy, what do you think are the most critical factors that investors should consider when evaluating opportunities in this space?</strong></p><p><strong>Mathew Cook</strong>: In my opinion investors should consider the following 5 critical factors:</p><p>鈼廟egulatory Landscape: Understanding the regulatory environment and potential hurdles is crucial. Investors should assess the company鈥檚 strategy for navigating approvals and compliance with health authorities.</p><p>鈼廠cientific Validity: Evaluating the underlying science and technology is essential. Investors should consider the robustness of the data supporting the therapy's efficacy and safety, including preclinical and clinical trial results.</p><p>鈼廋ompetitive Landscape: Analysing existing competitors and emerging therapies is vital.&nbsp; Investors should evaluate how the company differentiates its product and its potential to capture market share.</p><p>鈼廔ntellectual Property (IP): Strong IP protection is critical for maintaining competitive advantage. Investors should review the company鈥檚 patent portfolio and any potential risks related to IP infringement.</p><p>鈼廙anufacturing Capabilities: The ability to scale production efficiently and cost-effectively is vital for commercial success. Investors should assess the company鈥檚 manufacturing processes and partnerships.</p><p>&nbsp;<strong>#LBS: What are the most significant market barriers for cell and gene therapy companies trying to scale from niche treatments to more widespread applications, and how can businesses strategically overcome these obstacles to drive growth?</strong></p><p><strong>Mathew Cook</strong>: A few things come to mind:</p><p>鈼廐igh Development Costs: The costs associated with research, development, and clinical trials can be prohibitive. Companies can overcome this by seeking partnerships with larger pharmaceutical firms or engaging in public-private collaborations to share financial burdens.</p><p>鈼廙anufacturing Complexities: Producing cell and gene therapies at scale is technically challenging and costly. Companies can invest in advanced manufacturing technologies and automation to improve efficiency and reduce costs.</p><p>鈼廘imited Reimbursement Models: The high cost of therapies can lead to reimbursement challenges. Companies should work with payers to develop innovative pricing models, such as outcomes-based agreements, to demonstrate value and ensure coverage.</p><p><strong>#LBS: As the cell and gene therapy landscape becomes more competitive, how can companies&nbsp; differentiate their offerings in terms of value proposition, beyond just clinical efficacy, to capture&nbsp; market share and build a sustainable business model?&nbsp;</strong></p><p><strong>Mathew Cook: </strong></p><p>鈼廔nnovative Delivery Mechanisms: Invest in advanced delivery methods that enhance the efficacy and safety of therapies, such as localized delivery systems or combination therapies that synergize with existing treatments. </p><p>鈼廟eal-World Evidence (RWE): Generate and present real-world data demonstrating the effectiveness and safety of therapies outside of clinical trials.&nbsp;</p><p>鈼廎ocus on Rare Diseases: Target niche markets or rare diseases where competition may be lower and unmet needs are significant. This can lead to quicker regulatory approvals and a more focused marketing strategy.</p><p><strong>#LBS: What is your perspective on the impact and importance of events like the London Biotechnology&nbsp; Show in driving innovation and collaboration within the industry?</strong></p><p><strong>Mathew Cook: </strong>As you know I attended in May 2024 - Events like the London Biotechnology Show play a crucial role&nbsp; in driving innovation and collaboration within our industry. I have 3 points:&nbsp;</p><p>鈼廚etworking Opportunities: These events provide a platform for industry professionals, researchers, and investors to connect, fostering relationships that can lead to collaborations.</p><p>鈼廗nowledge Sharing: Conferences facilitate the exchange of ideas, research findings, and best practices.&nbsp;</p><p>鈼廔nspiration for Future Innovations: Exposure to cutting-edge research and successful case studies can inspire new ideas and approaches.</p> </div> </section> </article> </div> </main> <aside class="read-next outer"> <div class="inner"> <div class="read-next-feed"> <article class="post-card post tag-hash-cts "> <a class="post-card-image-link" href="/uk-approves-600mw-cottam-solar-farm-to-enhance-renewable-capacity/"> <img class="post-card-image" srcset="/content/images/size/w300/2024/09/Cottam-Solar-Farm.jpg 300w, /content/images/size/w600/2024/09/Cottam-Solar-Farm.jpg 600w, /content/images/size/w1000/2024/09/Cottam-Solar-Farm.jpg 1000w, 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[] : $interests $.ajax({ url: "https://api.resources.eventackle.com/subscription", type: 'post', headers:{ 'Content-Type':'application/json' }, data: JSON.stringify(data), complete: function () { }, success: function (data, status) { if(status == "success"){ $subForm.addClass('success').removeClass('invalid') $subsEmail.val('') } }, error: function(e){ $subForm.addClass('invalid').removeClass('success') } }); }) //subscription form submit let $authorForm = $('form[data-author-form]') $authorForm.submit(function(e){ e.preventDefault() $authorForm.removeClass('success invalid') let $authorEmail = $authorForm.find('input[name="email"]') let data = {} data.email = $authorEmail.val().trim() data.user_id = "" $.ajax({ url: "https://api.resources.eventackle.com/contribution", type: 'post', headers:{ 'Content-Type':'application/json' }, data: JSON.stringify(data), complete: function () { }, success: function (data, status) { if(status == "success"){ $authorForm.addClass('success') $authorEmail.val('') } }, error: function(e){ $authorForm.addClass('invalid') } }); }) }); function goBack(){ if(!window.history.back()){ window.close() } } </script> <script> $(document).ready(function () { // FitVids - start var $postContent = $(".post-full-content"); $postContent.fitVids(); // FitVids - end // Replace nav with title on scroll - start Casper.stickyNavTitle({ navSelector: '.site-nav-main', titleSelector: '.post-full-title', activeClass: 'nav-post-title-active' }); // Replace nav with title on scroll - end // Hover on avatar var hoverTimeout; $('.author-list-item').hover(function () { var $this = $(this); clearTimeout(hoverTimeout); $('.author-card').removeClass('hovered'); $(this).children('.author-card').addClass('hovered'); }, function () { var $this = $(this); hoverTimeout = setTimeout(function () { $this.children('.author-card').removeClass('hovered'); }, 800); }); }); </script> </body> </html>

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