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MOGAM :: Institute for Biomedical Research

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src="/resources/mogamwebsite/images/eng/img/icon_calender_color.png"></div> <span class="date">JANUARY 14</span> <button class="btn-close"><img src="/resources/mogamwebsite/images/eng/img/btn_close.png"></button> </div> <ul> <li> <span class="title">SYMPOSIUM</span> <p> 13th International<br> symposium on MPS and<br> related diseases </p> <span class="date">2014.08.05 ~ 09</span> <span class="place">Bahia, Brazil</span> </li> <li> <span class="title event">SYMPOSIUM</span> <p> 13th International<br> symposium on MPS and<br> related diseases </p> <span class="date">2014.08.05 ~ 09</span> <span class="place">Bahia, Brazil</span> </li> <li> <span class="title">SYMPOSIUM</span> <p> 13th International<br> symposium on MPS and<br> related diseases </p> <span class="date">2014.08.05 ~ 09</span> <span class="place">Bahia, Brazil</span> </li> <li> <span class="title">SYMPOSIUM</span> <p> 13th International<br> symposium on MPS and<br> related diseases </p> <span class="date">2014.08.05 ~ 09</span> <span class="place">Bahia, Brazil</span> </li> </ul> </div> <div class="search-bar"> <input placeholder="What are you looking for?"> <button> <img src="/resources/mogamwebsite/images/eng/img/btn_search.png" alt="search"> </button> </div> <div class="sections"> <section class="section-1"> <ol> <!-- <li class="key"> <div class="bg-box"> <div class="img"> <img src="/resources/mogamwebsite/images/eng/img/sec1_kv1.jpg" alt="세포가 있는 이미지"> <video autoplay muted loop src="/resources/mogamwebsite/mp4/eng/main_001_bg.mp4"></video> <img src="" data-web-img-url="" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec1_kv1_m.jpg" class="changable" alt="세포가 있는 이미지"/> </div> <div class="key1_btn-1 btns btn-1"> <a href=""> <img src="/resources/mogamwebsite/images/eng/img/btn_plus.png" alt="자세히 보기"> <div class="active"><img src="/resources/mogamwebsite/images/eng/img/btn_active.png"></div> </a> <div class="sayballon"> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sayballon_bl.png" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sayballon_tl.png" class="changable" alt=""/> <div class="txt-box bl"> <span>Lipid nanoparticle for mRNA delivery</span> <p> To deliver mRNA to target cells in the body, a carrier is required. MOGAM is conducting the research geared toward increasing the transfer efficiency of mRNA to target cells and lowering the toxicity using different types of nanoparticles. </p> </div> </div> </div> <div class="key1_btn-2 btns btn-2"> <a href=""> <img src="/resources/mogamwebsite/images/eng/img/btn_plus.png" alt="자세히 보기"> <div class="active"><img src="/resources/mogamwebsite/images/eng/img/btn_active.png"></div> </a> <div class="sayballon"> <div class="txt-box"> <span>mRNA design</span> <p> MOGAM is working on developing better therapeutics with improved efficiency and stability through protein and mRNA engineering strategies. </p> </div> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sayballon_tr.png" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sayballon_br.png" class="changable" alt=""/> </div> </div> <div class="btns btn-3"> <a href=""> <img src="/resources/mogamwebsite/images/eng/img/btn_plus.png" alt="자세히 보기"> <div class="active"><img src="/resources/mogamwebsite/images/eng/img/btn_active.png"></div> </a> <div class="sayballon"> <div class="txt-box"> <span>S Protein</span> <p> Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Quis ipsum suspendisse. </p> </div> <img src="/resources/mogamwebsite/images/eng/img/sayballon_tr.png"> </div> </div> </div> <div class="txt-box"> <span>Platform Technology</span> <p> mRNA /<br> Nanoparticle </p> </div> </li> <li class="sub"> <div class="bg-box"> <div class="img"> <video autoplay muted loop src="/resources/mogamwebsite/mp4/eng/main_002_bg.mp4"></video> <img src="" data-web-img-url="" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec1_kv2_m.jpg" class="changable" alt="세포가 있는 이미지"/> </div> <div class="key2_btn-1 btns btn-1"> <a href="" > <img src="/resources/mogamwebsite/images/eng/img/btn_plus.png" alt="자세히 보기"/> <div class="active"><img src="/resources/mogamwebsite/images/eng/img/btn_active.png"></div> </a> <div class="sayballon"> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sayballon_bl.png" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sayballon_tr2.png" class="changable" alt=""/> <div class="txt-box"> <span>Antibody screening system</span> <p> Antibodies can be effectively generated through a B cell library using human and mouse immune responses and a synthetic library of various antibody formats. </p> </div> </div> </div> <div class="btns btn-2"> <a href="" class="btn-2"> <img src="/resources/mogamwebsite/images/eng/img/btn_plus.png" alt="자세히 보기" /> <div class="active"><img src="/resources/mogamwebsite/images/eng/img/btn_active.png"></div> </a> <div class="sayballon"> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sayballon_tr.png" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sayballon_tr.png" class="changable" alt=""/> <div class="txt-box"> <span>Hyper-stable single domain antibody</span> <p> MOGAM developed hyper-stable VH domain antibody similar to the IgG level using own protein engineering & screening system. </p> </div> </div> </div> <div class="btns btn-3"> <a href="" class="btn-3"> <img src="/resources/mogamwebsite/images/eng/img/btn_plus.png" alt="자세히 보기"> <div class="active"><img src="/resources/mogamwebsite/images/eng/img/btn_active.png"></div> </a> <div class="sayballon"><img src="/resources/mogamwebsite/images/eng/img/sayballon_tr.png"></div> </div> </div> <div class="txt-box"> <span>Platform Technology</span> <p> Protein<br> Engineering </p> </div> </li> --> <li class="object"> <div class="bg-box"> <div class="img"> <video autoplay muted loop src="/resources/mogamwebsite/mp4/eng/main_003_bg.mp4"></video> <img src="" data-web-img-url="" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec1_kv3_m.jpg" class="changable" alt="세포가 있는 이미지"/> </div> <div class="key2_btn-1 btns btn-1"> <a href="/eng/platformtechnology#nano" > <img src="/resources/mogamwebsite/images/eng/img/object01.png" alt="자세히 보기"/> <div class="hover"><img src="/resources/mogamwebsite/images/eng/img/object01-hover.png"/></div> </a> <svg class="btn-line"> <polyline points="120 0 50 0 0 50" fill="transparent" stroke="#fff" stroke-width="3" /> </svg> </div> <div class="btns btn-2"> <a href="/eng/platformtechnology#protein" class="btn-2"> <img src="/resources/mogamwebsite/images/eng/img/object02.png" alt="자세히 보기" /> <div class="hover"><img src="/resources/mogamwebsite/images/eng/img/object02-hover.png"/></div> </a> <svg class="btn-line"> <polyline points="0 50 50 0 120 0" fill="transparent" stroke="#fff" stroke-width="3" /> </svg> </div> </div> <div class="txt-box"> <p> AI Technology </p> </div> </li> </ol> <div class="btn-box"> <a href="/eng/platformtechnology#tech" id="exploreSec1"><img src="/resources/mogamwebsite/images/eng/img/btn_explore.png"></a> </div> <button class="page-down-indicator"> <img src="/resources/mogamwebsite/images/eng/img/btn_page_down_indicator.png" alt="pagedown-indicator"> </button> <canvas id="canvas"></canvas> </section> <section class="section-2"> <div class="inner-section"> <div class="identity clearfix"> <div class="txt-box"> <span class="sub-tit"> M0GAM'S<br> IDENTITY & VISION </span> <em>Identity</em> </div> <div class="img-box"> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sec2_thumb.png" data-tablet-img-url="/resources/mogamwebsite/images/eng/img/sec2_thumb_t.png" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec2_thumb_m.png" class="changable" alt="MOGAM'S IDENTITY & VISION"/> </div> </div> <div class="vision"> <ol class="img-box"> <li> <button> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb_0.jpg" data-tablet-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb_0_t.jpg" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb_0_m.jpg" class="changable" alt="MOGAM'S IDENTITY & VISION"/> </button> </li> <li> <button> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb_1.jpg" data-tablet-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb_1_t.jpg" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb_1_m.jpg" class="changable" alt="MOGAM'S IDENTITY & VISION"/> </button> </li> </ol> <div class="txt-box"> <span class="onShow"> <em> Helping<br class="m"> patients and<br class="pc"> society<br class="m"> by developing new<br class="m"><br class="pc"> treatments </em> </span> <span> <em> Leading a novel drug <br class="pc"> development <br class="m"> paradigm <br class="pc"> through the <br class="pc"> combination of AI <br class="pc"> technology and BIO technology </em> </span> </div> </div> <div class="therapeutic-area clearfix"> <div class="txt-box"> <span class="sub-tit"> THERAPEUTIC AREA </span> <div class="tits"> <ol class="tit"> <li><a href="/eng/therapeuticarea#raredisease">Rare Disease</a></li> <li class="large-m"><a href="/eng/therapeuticarea#infectiousdisease">Infectious<br class="m"> Disease</a></li> <li><a href="/eng/therapeuticarea#oncology">Oncology</a></li> </ol> </div> <span class="page-index">1 / 3</span> <button class="btn-prev"><img src="/resources/mogamwebsite/images/eng/img/prev-arrow.png" alt="prev"></button> <button class="btn-next"><img src="/resources/mogamwebsite/images/eng/img/next-arrow.png" alt="next"></button> <a href="/eng/therapeuticarea#raredisease" class="explore" id="exploreSec2"> <img src="/resources/mogamwebsite/images/eng/img/btn_explore.png" alt="explore"> </a> </div> <ol class="slide"> <li> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb0.jpg" data-tablet-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb0_t.jpg" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb0_m.jpg" class="changable" alt=""/> <div class="info-box"> <span class="tit">Challenges in developing drugs for Rare Disorders</span> <span class="des">MOGAM hopes that mRNA therapy will ease the physical, financial and psychological burdens on patients with rare diseases and their families.</span> </div> </li> <li> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb2.jpg" data-tablet-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb2_t.jpg" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb2_m.jpg" class="changable" alt=""/> <div class="info-box"> <span class="tit"> Infectious diseases are disorders caused by<br> pathogenic microorganisms, such as bacteria, fungi, parasites, or viruses </span> <span class="des">A numerous variety of microorganisms are found nearly everywhere in our environment. Although they are normally harmless or even helpful, some microorganisms called pathogens can cause diverse infectious diseases, including chickenpox, flu, herpes zoster, ...</span> </div> </li> <li> <img src="" data-web-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb3.jpg" data-tablet-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb3_t.jpg" data-mobile-img-url="/resources/mogamwebsite/images/eng/img/sec2_slide_thumb3_m.jpg" class="changable" alt=""/> <div class="info-box"> <span class="tit">Our Oncology</span> <span class="des">Targeted therapy against cancer driver mutation is very powerful; however, drug resistance significantly reduces its therapeutic effect. <br/>We find the best way to overcome this challenge using AI. </span> </div> </li> </ol> </div> </div> </section> <section class="section-3"> <div class="inner-section"> <div class="tit-box"> <span class="tit">PUBLICATIONS</span> <a class="more-btn" href="/eng/publications">See all Content</a> </div> <ul class="publication"> <li> <a href="https://www.nature.com/articles/s41598-024-67000-1" target="_blank"> <div class="txt-box"> <span class="tit">2024</span> <span class="where">- Scientific Reports</span> <p>Comparative network-based analysis of toll-like receptor agonist, L-pampo signaling pathways in immune and cancer cells</p> </div> <img src="/resources/mogamwebsite/images/eng/img/sec3_thumb0.png"> </a> </li> <li> <a href=" https://pubmed.ncbi.nlm.nih.gov/35090381/" target="_blank"> <div class="txt-box"> <span class="tit">2022</span> <span class="where">- MAbs</span> <p>Structural and functional characterization of a monoclonal antibody blocking TIGIT</p> </div> <img src="/resources/mogamwebsite/images/eng/img/sec3_thumb0.png"> </a> </li> <li> <a href="https://www.frontiersin.org/articles/10.3389/fimmu.2021.778829/full" target="_blank"> <div class="txt-box"> <span class="tit">2021</span> <span class="where">- Frontiers in Immunology</span> <p>MG1141A as a highly potent monoclonal neutralizing antibody against SARS-CoV-2 variants</p> </div> <img src="/resources/mogamwebsite/images/eng/img/sec3_thumb0.png"> </a> </li> <li> <a href="https://onlinelibrary.wiley.com/doi/10.1002/rth2.12438" target="_blank"> <div class="txt-box"> <span class="tit">2020</span> <span class="where">- Research and Practice in Thrombosis and Haemostasis</span> <p>MG1113, a specific anti–tissue factor pathway inhibitor antibody, rebalances the coagulation system and promotes hemostasis in hemophilia</p> </div> <img src="/resources/mogamwebsite/images/eng/img/sec3_thumb0.png"> </a> </li> <li> <a href="https://www.nature.com/articles/s41598-020-74772-9" target="_blank"> <div class="txt-box"> <span class="tit">2020</span> <span class="where">- Scientific Reports</span> <p>Abrogation of HLA surface expression using CRISPR/Cas9 genome editing: a step toward universal T cell therapy</p> </div> <img src="/resources/mogamwebsite/images/eng/img/sec3_thumb0.png"> </a> </li> </ul> </div> </section> <div class="goto-top"> <button> <img src="/resources/mogamwebsite/images/eng/img/btn_gotop.png" alt="최상단으로"> </button> </div> </div> <!--<section class="section-4"> <div class="inner-section"> <div class="board"> <div class="inner-board clearfix"> <div class="tit-box"> <span class="tit">PRESS RELEASE</span> </div> <div class="board-list"> <ul> <li> <a href="/eng/pressrelease-view"> <span>Mogam Research Center, 2021 Open Innovation'LNP Research Project' Contest</span><em>13 August 2020</em> </a> </li> <li> <a href="/eng/pressrelease-view"> <span>Aachen University of Technology “Mogam Haus” built by the former president of the former president Young-seop Heo</span><em>20 October 2020</em> </a> </li> <li> <a href="/eng/pressrelease-view"> <span>Mogam Research Institute confirms the possibility of universal treatment for hepatitis B'renverbimab'</span><em>20 October 2020</em> </a> </li> <li> <a href="/eng/pressrelease-view"> <span>Mogam Research Institute announces basic research results of'MSLNxCD3 double antibody'</span><em>20 October 2020</em> </a> </li> <li> <a href="/eng/pressrelease-view"> <span>Mogam Research Institute, “gene editing” homogeneous CAR-T.. “Immune rejection reaction”</span><em>20 October 2020</em> </a> </li> <li> <a href="/eng/pressrelease-view"> <span>Mogam-Green Cross MS, joint development partnership for'Corona 19 Immunity Diagnosis Kit'</span><em>20 October 2020</em> </a> </li> <li> <a href="/eng/pressrelease-view"> <span>Mogam-GC Green Cross Mini Conference held.. “Shared” and “Exchange”</span><em>20 October 2020</em> </a> </li> </ul> <div class="page-index"> <ol> <li class="onShow"><button></button></li> <li><button></button></li> <li><button></button></li> <li><button></button></li> </ol> <a class="more-btn" href="/eng/pressrelease">See all Content</a> </div> </div> </div> </div> </div> </section>--> <!--<section class="section-5"> <div class="inner-section"> <div class="tit-box"> <span class="tit">EVENTS</span> <a class="more-btn" href="/eng/events">See all Content</a> </div> <div class="list-box"> <ul> <li> <a href="/eng/events-view"> <span class="cate">seminar</span> <span class="tit">MOGAM Research Center, Institute Invitation Seminar<br><em>-Lee dong yoon</em></span> <div class="date-box"> <span class="date">Date. 20 March 2021</span> <span class="location">Location. R&Dcenter 3f WEGO hall</span> </div> </a> </li> <li> <a href="/eng/events-view"> <span class="cate">seminar</span> <span class="tit">MOGAM Research Center, Institute Invitation Seminar<br>-Lee dong yoon</span> <div class="date-box"> <span class="date">Date. 20 March 2021</span> <span class="location">Location. R&Dcenter 3f WEGO hall</span> </div> </a> </li> <li> <a href="/eng/events-view"> <span class="cate">seminar</span> <span class="tit">MOGAM Research Center, Institute Invitation Seminar<br>-Lee dong yoon</span> <div class="date-box"> <span class="date">Date. 20 March 2021</span> <span class="location">Location. R&Dcenter 3f WEGO hall</span> </div> </a> </li> <li> <a href="/eng/events-view"> <span class="cate">seminar</span> <span class="tit">MOGAM Research Center, Institute Invitation Seminar<br>-Lee dong yoon</span> <div class="date-box"> <span class="date">Date. 20 March 2021</span> <span class="location">Location. 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