CINXE.COM

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</div> <div id="block-system-main" class="block block-system"> <div class="content"> <div id="node-1095786" class="node node-product-categories clearfix" about="/products/get-superior-accuracy-rd-systems-luminex-assays" typeof="sioc:Item foaf:Document"> <span property="dc:title" content="Get Superior Accuracy & Precision with R&D Systems Luminex庐 Assays" class="rdf-meta element-hidden"></span><span property="sioc:num_replies" content="0" datatype="xsd:integer" class="rdf-meta element-hidden"></span> <div class="content"> <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><style type="text/css">.first {margin-left:0} .last {margin-right:0} .container_12 .grid_1 {width:30px;} .grid_3 .first, .grid_3, .grid_3 .last {width:220px;} </style> <p>Spike recovery and linearity of dilution are two commonly used methods for measuring the accuracy and precision of an assay. We tested our Luminex Assays against two leading competitors and found that our assays provide superior accuracy and precision compared to the competition.</p> <h2>Superior Accuracy with R&D Systems<sup>庐</sup> Luminex Assays</h2> <p>The range that is generally considered acceptable for spike recovery is 70% - 130% (horizontal red bars). As shown below, all R&D Systems Luminex Assays fell within this acceptable range. In contrast, no assays from Competitor 1, and only one assay from Competitor 2 fell within the acceptable range.</p> <p><a class="rnd_image_popup" href="//resources.rndsystems.com/images/site/serum-spike-recovery-fg.png?v=2" title="Serum Spike Recovery"><img alt="Serum Spike Recovery" src="//resources.rndsystems.com/images/site/serum-spike-recovery-tn.png?v=2" width="700" /><br /> View Larger</a></p> <p><strong>Serum Spike Recovery.</strong> For each Luminex assay, a known concentration of recombinant protein was spiked into calibrator diluent (reference value) and a pooled serum sample. Unspiked serum sample values were subtracted from the spiked serum values and compared against the reference value to determine % recovery.</p> <h2>Superior Precision with R&D Systems Luminex Assays</h2> <p>The range that is generally considered acceptable for linearity of dilution is 70%-130% (red bars). As shown below, the linearity of the R&D Systems TNF-alpha Luminex Assay fell within this acceptable range, but the competitor assays did not.</p> <div class="grid_3 first"> <p><a class="rnd_image_popup" href="//resources.rndsystems.com/images/site/ford-dilution-rnd.jpg?v=2" title="Linearity of Dilution."><img alt="ford dilution rnd systems" src="//resources.rndsystems.com/images/site/ford-dilution-rnd-tn.png?v=2" width="200" /><br /> View Larger</a></p> </div> <div class="grid_3"> <p><a class="rnd_image_popup" href="//resources.rndsystems.com/images/site/ford-dilution-comp1.jpg" title="Linearity of Dilution."><img alt="ford dilution competitor 1" src="//resources.rndsystems.com/images/site/ford-dilution-comp-tn.png?v=2" width="200" /><br /> View Larger</a></p> </div> <div class="grid_3 last"> <p><a class="rnd_image_popup" href="//resources.rndsystems.com/images/site/ford-dilution-comp2.jpg" title="Linearity of Dilution."><img alt="ford dilution competitor 2" src="//resources.rndsystems.com/images/site/ford-dilution-comp2-tn.png?v=2" width="200" /><br /> View Larger</a></p> </div> <p><strong>Linearity of Dilution.</strong> A known concentration of recombinant human TNF-alpha was spiked into serum or plasma and assayed by two-fold serial dilutions for each Luminex Assay. Sample values were back-calculated based on the standard curve, normalized to the initial sample dilution, and represented as % recovery vs. sample dilution.</p> <p><a class="orange_button" href="/luminex/analytes" style="padding: 8px 12px; font-size:17px; display:inline-block;">Luminex Assay Customization Tool</a><br /> <a href="/products/luminex-assays" style="margin:0 5px;">Learn about Luminex Assays</a></p> <div style="clear:both"> </div>  <p><span style="font-size:10px;"><span style="color: rgb(51, 51, 51); font-family: arial, sans-serif;"> Luminex<sup>庐</sup> is a trademark of Luminex Corporation.</span></span></p> </div></div></div> </div> </div> </div> </div> <div id="block-et-relatedcontent-menu-et-relatedcontent-menu-block" class="block block-et-relatedcontent-menu"> <div class="content"> <div class="relatedcontent_links"><h3>Related Information</h3></div> <div class="row evenheight"><div class="col-md-6 col-xs-12"><a href="https://www.rndsystems.com/target/multiplex-cytokine-assay-kits" class="btn btn-senary btn-relatedinfo" itemprop="relatedLink">Multiplex Cytokine Assay Kits</a></div></div> </div> </div> <div id="block-block-26" class="block block-block"> <div class="content">  <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true" style="display: none;"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" aria-describedby="snapins_bodytext" style="height: 48px;"> <img id="embeddedServiceAvatar" /> <span class="embeddedServiceTitleText" id="snapins_titletext">Need help?</span> <button type="button" id="closeInvite" class="embeddedServiceCloseIcon" aria-label="Exit invitation">×</button> </div> <div class="embeddedServiceInvitationBody"> <p id="snapins_bodytext">How can we help you?</p> </div> <div class="embeddedServiceInvitationFooter" aria-describedby="snapins_bodytext"> <button type="button" class="embeddedServiceActionButton" id="rejectInvite">Close</button> <button type="button" class="embeddedServiceActionButton" id="acceptInvite">Start Chat</button> </div> </div> </div> </div> </div> </div> <div class="grid_3"> <div class="column_menu"> <a href="/resources/literature" class="parent">Literature</a><div class="right_menu_contents hide"><ul class="menu"><li class="first leaf"><a href="/resources/articles" title="" id="menu-literature-29336">Articles</a></li> <li class="leaf"><a href="/resources/literature" title="" id="menu-literature-29341">Literature</a></li> <li class="last leaf"><a href="/resources/posters" title="" id="menu-literature-29346">Posters</a></li> </ul></div><a href="/Products" class="parent">Product Categories</a><div class="right_menu_contents"><ul class="menu"><li class="first collapsed"><a href="/products/proteins" id="menu-products-12696">Recombinant Proteins</a></li> <li class="leaf"><a href="/products/good-manufacturing-practices-gmp-grade-proteins" id="menu-products-112931">GMP Proteins</a></li> <li class="leaf"><a href="/products/enzymes" id="menu-products-121111">Enzymes</a></li> <li class="leaf"><a href="/products/small-molecules-peptides" id="menu-products-112711">Small Molecules & Peptides</a></li> <li class="leaf"><a href="/products/immunotherapy" id="menu-products-121081">Immunotherapy</a></li> <li class="leaf"><a href="/products/elispot-kits-fluorospot-kits" id="menu-products-12681">ELISpots</a></li> <li class="leaf"><a href="/products/cdna-clones" title="R&D Systems offers large selections of cDNA Clones and expression-ready vectors. 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