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How long a new drug takes to go through clinical trials | Cancer Research UK
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href="https://www.cancerresearchuk.org/get-involved/volunteer/volunteer-in-our-shops" class="level3">Volunteer in our shops</a></li><li><a href="https://www.cancerresearchuk.org/get-involved/volunteer/help-at-an-event" class="level3">Help at an event</a></li><li><a href="https://www.cancerresearchuk.org/get-involved/volunteer/help-us-raise-money" class="level3">Help us raise money</a></li><li><a href="https://www.cancerresearchuk.org/how-to-cancer-campaign" class="level3">Campaign for us</a></li><li><a href="https://www.cancerresearchuk.org/get-involved/volunteer" class="level3">More...</a></li></ul></li><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/get-involved/do-your-own-fundraising" class="level2">Do your own fundraising</a></p><ul><li><a href="https://www.cancerresearchuk.org/get-involved/do-your-own-fundraising/fundraising-ideas" class="level3">Fundraising ideas</a></li><li><a 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href="https://www.cancerresearchuk.org/get-involved/become-a-partner" class="level3">Become a partner</a></li><li><a href="https://www.cancerresearchuk.org/get-involved/donate/kids-and-teens" class="level3">Cancer Research UK for Children & Young People</a></li><li><a href="https://www.cancerresearchuk.org/get-involved/we-are" class="level3">Our We Are campaign</a></li></ul></li></ul> </div> </li><li class="mm-item"><p><a href="https://www.cancerresearchuk.org/our-research" class="mm-item-link">Our research</a><span class="cr-i cr-i--chevron-down"></span></p> <div style="width: 940px"> <ul class="list-content" id="our-research-menu"><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-type" class="level2">By cancer type</a></p><ul><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-type/our-research-on-brain-tumours" class="level3">Brain tumours</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-type/our-research-on-skin-cancer" class="level3">Skin cancer</a></li><li><a href="/our-research/our-research-by-cancer-type/our-research-on-breast-cancer" class="level3">Breast cancer</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-type" class="level3">All cancer types</a></li></ul></li><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-subject" class="level2">By cancer topic</a></p><ul><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-subject/our-research-on-clinical-trials" class="level3">New treatments</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-subject/our-research-on-cancer-biology" class="level3">Cancer biology</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-subject/our-research-on-cancer-drugs" class="level3">Cancer drugs</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-by-cancer-subject" class="level3">All cancer subjects</a></li></ul></li><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/our-research/our-research-near-you" class="level2">Near you</a></p><ul><li><a href="https://www.cancerresearchuk.org/our-research/our-research-near-you/our-research-in-belfast" class="level3">Belfast</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-near-you/our-research-in-cardiff" class="level3">Cardiff</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-near-you/our-research-in-edinburgh" class="level3">Edinburgh</a></li><li><a href="https://www.cancerresearchuk.org/our-research/our-research-near-you" class="level3">All locations</a></li></ul></li><li class="toplevel"><p>More...</p><ul><li><a href="https://www.cancerresearchuk.org/our-progress" class="level3">Our achievements timeline</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-research-strategy" class="level3">Our research strategy</a></li><li><a href="https://www.cancerresearchuk.org/our-research/involving-animals-in-research" class="level3">Involving animals in research</a></li></ul></li></ul> </div> </li><li class="mm-item"><p><a href="https://www.cancerresearchuk.org/funding-for-researchers" class="mm-item-link">Funding for researchers</a><span class="cr-i cr-i--chevron-down"></span></p> <div style="width: 940px"> <ul class="list-content" id="funding-for-researchers-menu"><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/funding-for-researchers" class="level2">Research opportunities</a></p><ul><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/research-opportunities-in-basic-science-and-discovery-research" class="level3">For discovery researchers</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/clinical-research" class="level3">For clinical researchers</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/research-opportunities-in-population-and-behavioural-research" class="level3">For population researchers</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/drug-discovery-and-development" class="level3">In drug discovery & development</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/research-opportunities-in-early-detection-and-diagnosis" class="level3">In early detection & diagnosis</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/opportunities-for-phd-students-and-postdoc-researchers" class="level3">For students & postdocs</a></li></ul></li><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-funding-schemes?items_per_page=40" class="level2">Our funding schemes</a></p><ul><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-funding-schemes/career-development-fellowship" class="level3">Career Development Fellowship</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-funding-schemes/discovery-programme-awards" class="level3">Discovery Programme Awards</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-funding-schemes/clinical-trial-award-0" class="level3">Clinical Trial Award</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-funding-schemes/biology-to-prevention-award" class="level3">Biology to Prevention Award</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-funding-schemes" class="level3">View all schemes and deadlines</a></li></ul></li><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/funding-for-researchers/applying-for-funding" class="level2">Applying for funding</a></p><ul><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/applying-for-funding/start-your-funding-application-online" class="level3">Start your application online</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/applying-for-funding/how-to-make-a-successful-application" class="level3">How to make a successful application</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/applying-for-funding/funding-committees" class="level3">Funding committees</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/applying-for-funding/how-to-make-a-successful-application/successful-applicant-case-studies" class="level3">Successful applicant case studies</a></li></ul></li><li class="toplevel"><p><a href="https://www.cancerresearchuk.org/funding-for-researchers/how-we-deliver-research" class="level2">How we deliver research</a></p><ul><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-research-strategy" class="level3">Our research strategy</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/our-research-infrastructure" class="level3">Our research infrastructure</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/research-events-and-conferences" class="level3">Events and conferences</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/how-we-deliver-research/our-research-partnerships" class="level3">Our research partnerships</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/facts-and-figures-about-our-research-funding" class="level3">Facts & figures about our funding</a></li></ul></li><li class="toplevel"><p>More...</p><ul><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/patient-involvement-toolkit-for-researchers" class="level3">Patient involvement toolkit for researchers</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/research-career-development-opportunities" class="level3">Develop your research career</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/how-we-deliver-research/recently-funded-awards" class="level3">Recently funded awards</a></li><li><a href="https://www.cancerresearchuk.org/funding-for-researchers/manage-your-research-grant" class="level3">Manage your research grant</a></li><li><a href="https://www.cancerresearchuk.org/home/funding-for-researchers/manage-your-research-grant/tell-us-about-new-publications" class="level3">Notify us of new publications</a></li></ul></li></ul> </div> </li><li class="mm-item"><p><a href="https://www.cancerresearchuk.org/get-involved/ways-to-shop" class="mm-item-link">Shop</a><span class="cr-i cr-i--chevron-down"></span></p> <div style="width: 940px"> <ul class="list-content" id="shop-menu"><li class="toplevel"><p><a 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class="breadcrumb"><a href="/">Home</a><img src="/sites/all/themes/custom/cruk/images/breadcrumb-arrow.png" alt="" /><a href="/about-cancer">About Cancer</a><img src="/sites/all/themes/custom/cruk/images/breadcrumb-arrow.png" alt="" /><a href="/about-cancer/find-a-clinical-trial" class="menu-node-unpublished menu-node-unpublished menu-node-unpublished">Find a clinical trial</a><img src="/sites/all/themes/custom/cruk/images/breadcrumb-arrow.png" alt="" /><a href="/about-cancer/find-a-clinical-trial/how-clinical-trials-are-planned-and-organised" class="menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished menu-node-unpublished">How clinical trials are planned and organised</a><img src="/sites/all/themes/custom/cruk/images/breadcrumb-arrow.png" alt="" />How long a new drug takes to go through clinical trials</div> </div> </div> </header> <div class="page"> <div class="wrapper no-gutter container"> <main role="main" id="main-content" tabindex="-1"> <!-- start of main content --> <h1>How long a new drug takes to go through clinical trials</h1> <div class="cancerinfo_stand_20_60_20" > <div class="column-middle-right no-gutter row-10-col col-md-10 col-md-push-2 col-sm-12 col-xs-12"> <div class="column-middle col-md-7 col-sm-7 col-xs-10"> <div class="hero-section-narrow"> </div> </div> <div class="column-right col-md-3 col-sm-3 col-xs-10"> </div> <div class="column-middle col-md-7 col-sm-7 col-xs-10"> <div id="panel-3" class="panel-box ln-landing-body"> <div class="panel-pane pane-entity-field pane-node-body" > <div class="pane-content"> <div class="field field-type-text-with-summary"> <div class="field-item" property="schema:mainContentOfPage content:encoded"> <p>This page is about the things that can affect how long it takes for a new drug to go through clinical trials. There is information about</p> <p><a href="#testing">Drug testing and licensing</a><br /> <a href="#factors">Factors that affect how long trials take</a><br /> </p> <h2> <a id="testing" name="testing"></a>Drug testing and licensing</h2> <p>All new drugs and treatments have to be thoroughly tested before they are licensed and available for patients.</p> <p>A new drug is first studied in the laboratory. If it looks promising, it is carefully studied in people. It may be then licensed if the trial shows that it works well and doesn’t cause too many side effects. You may hear this process called ‘from bench to bedside’. </p> <p>There is no typical length of time it takes for a drug to be tested and approved. It might take 10 to 15 years or more to complete all <a href="/about-cancer/find-a-clinical-trial/what-clinical-trials-are/phases-of-clinical-trials">3 phases of clinical trials</a> before the licensing stage. But this time span varies a lot.</p> <p>There are many factors that affect how long it takes for a drug to be licensed.<br /> </p> <h2><a id="factors" name="factors"></a>Factors that affect how long trials take<br /> </h2> <h2>The type of cancer</h2> <p>Clinical trials for rarer cancers often take longer because there are fewer patients available to take part. Research teams from several different countries may need to work together so there are enough patients. This can mean the trial takes longer to organise and set up. International trials can often recruit people more quickly and so might be quicker in the long run.</p> <p>Researchers running clinical trials for more common cancers are generally able to find enough people to take part more easily.</p> <h2>The type of treatment</h2> <p>Trials that use new methods of giving treatment, such as a new way to give radiotherapy for example, may take longer to set up and run. This is because the research teams need specialist equipment and extra training. These trials may only be able to run in a small number of hospitals compared to trials using standard ways of giving treatment. </p> <p>How long treatment takes can also affect the results. It is likely to be quicker to get results for a trial looking at a single dose or short course of treatment. This is in comparison to a treatment that lasts for months or even years.</p> <h2>The type of trial</h2> <p>Some trials look at treatments to prevent cancer or ways of screening for cancer. Screening means testing for cancer in people who don’t have any signs or symptoms.</p> <p>People who join screening or prevention trials haven’t been diagnosed with cancer. The research team will often want to follow them for many years to see who develops cancer and who doesn’t.</p> <p>In people who have a high risk of developing cancer, they may then compare the different trial groups to see if a particular treatment can help prevent cancer. Or whether a test can help to diagnose it early.</p> <p>These trials often take a long time to get results compared to treatment trials. It can take years to see a clear difference in the number of people in the different groups who go on to develop cancer.</p> <h2>The number of patients needed</h2> <p>Experts in statistics look at what the research team want to find out and the design of the trial. They then work out how many patients need to take part in the trial. If there aren’t enough patients taking part, the results may not be reliable. </p> <h2>The follow up period</h2> <p>As part of a trial, research teams look at how well people are doing for some time after they have treatment. This is to see how well the treatment works over a longer period of time. And to find out more about long term side effects.</p> <p>Follow up periods can range from a few months to more than 10 years. This depends on the type of treatment and the group of patients. Follow up might be longer for a trial looking at screening or prevention.</p> <h2>Any problems with the new treatment</h2> <p>There may be problems with new drugs or treatments that the researchers don't know about until they run the trials. There could be unexpected side effects or reactions to treatment. Or there may be difficulties in giving the treatment to patients.</p> <p>Problems with the new treatment may mean the trial takes longer to complete.</p> <h2>Related information</h2> <p>We have information about </p> <p><a href="/about-cancer/find-a-clinical-trial">Find a clinical trial</a></p> <p><a href="/about-cancer/find-a-clinical-trial/clinical-trial-results/how-clinical-trial-results-are-used">Clinical trial results</a></p> <p><a href="/about-cancer/what-is-cancer/understanding-statistics-in-cancer-research">Understanding statistics in cancer research</a></p> <p> </p> </div> </div> </div> </div> </div> <div id="panel-5"> <div class="panel-pane pane-entity-field pane-node-field-section-reviewed section-review-date" > <h2 class="pane-title">Last reviewed</h2> <div class="pane-content"> <div class="field field-type-datetime"> <div class="field-item" property="schema:lastReviewed"><time property="schema:lastReviewed" datatype="xsd:dateTime" content="2022-02-01T00:00:00+00:00" 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