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Inspiring Target:Interleukin 4 Receptor - ACROBiosystems

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<div class="pane_box_link"> <h2>Cell Activation</h2> <ul> <li><a href="/P5481-GMP-Monoclonal-Anti-Human-CD3-Antibody-%28OKT3%29-DMF-Filed.html" >Activation Antibodies</a></li> <li><a href="/A1595-ActiveMax®-Cytokines.html" >ActiveMax - Target Specific Beads</a></li> <li><a href="/P4836-ActiveMax%C2%AE-Human-T-cell-ActivationExpansion-CD3CD28-Beads-Premium-grade(Pre-GMP) (Pre-GMP)-DMF-Filed.html" >Activation CD3/CD28 Beads</a></li> <li><a href="/A2107-Solutions-for-T-Cell-Activation-and-Culture.html" >Solutions for T Cell Activation and Culture</a></li> <li><a href="/A2107-Solutions-for-T-Cell-Activation-and-Culture.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Cell Media Additives</h2> <ul> <li><a href="/A2560-ECMproteins.html" >Extracellular Matrix (ECM) Proteins</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix Basement Membrane Extracts</a></li> <li><a href="/A2612-Laminin.html" >Laminin Proteins</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cell Culture Medium</h2> <ul> <li><a href="/A2660-T-cell-culture-media.html" >CelThera™ GMP T Cell Expansion Medium</a></li> </ul> </div> <div class="pane_box_link"> <h2>Others</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> <li><a href="/A1888-Custom-GMP-Services.html" >Custom GMP Protein Services</a></li> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >More >></a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Kits & Assay Reagents <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box4 pane_boxB"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/Product_hand05.jpg" alt="Kits & Assay Reagents"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>ELISA</h2> <ul> <li><a 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href="/A2146-Nuclease-Detection-Kits.html" >RNase / DNase Detection Kits</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" >Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="/search-keywords-elispot.html" >ELISpot Assay Kits</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title">Viral Antigens&Antibodies&Kits <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box5 pane_boxB"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/Product_hand02.jpg" alt="Viral Antigens"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>SARS-CoV-2</h2> <ul> <li><a href="/A1226-SARS-CoV-2_spike_mutants.html" >Variants of SARS-CoV-2 SARS-CoV-2 Related Products</a></li> <li><a href="/A1111-SARS-CoV-2-Related-Products.html" >SARS-CoV-2 Related Products</a></li> <li><a href="/A1167-Solutions-for-COVID-19-vaccine-safety-and-immunogenicity-evaluation.html" >Workflow for Vaccine R&D</a></li> </ul> </div> <div class="pane_box_link"> <h2>Varicella Zoster Virus</h2> <ul> <li><a href="/search-keywords-Glycoprotein E (VZV).html" >Glycoprotein E (VZV Antigen)</a></li> <li><a href="/search-keywords-VZV-nature-1-w-na1.html" >Anti-Glycoprotein E Antibody</a></li> <li><a href="/A2374-VZV-vaccine.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Influenza Virus</h2> <ul> <li><a href="/L-141-Hemagglutinin%20(HA).html" >Natural HA Trimer</a></li> <li><a href="/L-332-Neuraminidase%20(NA).html" >Natural NA Tetramer</a></li> <li><a href="/A2523-Flu.html" >HA & NA Antibody</a></li> <li><a href="/A2502-Influenza-Vaccine-Research-Customized-Services.html" >Customized Service</a></li> <li><a href="/A2523-Flu.html" >More >></a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Respiratory Syncytial Virus</h2> <ul> <li><a href="/search-nature-6-molecule-1484-keywords-RSV-w-na6_mo1484.html" >Pre-fusion Glycoprotein</a></li> <li><a href="/search-nature-6-keywords-RSV-molecule-1530-w-na6_mo1530.html" >Post-fusion Glycoprotein</a></li> <li><a href="/search-nature-1-molecule-1627-keywords-RSV-w-mo1627_na1.html" >Anti-RSV Pre-Fusion Antibody</a></li> <li><a href="/search-nature-1-molecule-1724-keywords-RSV-w-na1_mo1724.html" >Anti-RSV Post-fusion Antibody</a></li> <li><a href="/A2222-RSV.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Rabies Virus</h2> <ul> <li><a href="/L-1235-Glycoprotein%20(RABV).html" >Glycoprotein</a></li> <li><a href="/L-1739-Nucleoprotein.html" >Nucleoprotein</a></li> <li><a href="/P7526-Mouse-Anti-RABV-Nucleoprotein-Antibody-IgG-Titer-Serologic-Assay-Kit-%28ELISA%29.html" >Anti-RABV Nucleoprotein Antibody Kit </a></li> <li><a href="/P6055-Mouse-Anti-RABV-Glycoprotein-Antibody-IgG-Titer-Serologic-Assay-Kit-%28ELISA%29.html" >Anti-RABV Glycoprotein Antibody Kit </a></li> <li><a href="/A2438-RABV.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Herpes Virus</h2> <ul> <li><a href="/A2374-VZV-vaccine.html" >VZV</a></li> <li><a href="/A1658-virustop.html#module=ViruStop7" >HSV</a></li> <li><a href="/A1658-virustop.html#module=ViruStop13" >EBV</a></li> <li><a href="/A1658-virustop.html#module=ViruStop19" >HCMV</a></li> <li><a href="/A2642-Herpesviruses.html" >More >></a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Other Viruses</h2> <ul> <li><a href="/A1658-virustop.html#module=ViruStop2" >Influenza virus</a></li> <li><a href="/A1658-virustop.html#module=ViruStop4" >MPXV</a></li> <li><a href="/A1658-virustop.html#module=ViruStop5" >HIV</a></li> <li><a href="/A2438-RABV.html" >RABV</a></li> <li><a href="/A1658-virustop.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>ViruStop Services</h2> <ul> <li><a 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>Deep Array Probes</a></li> <li><a href="/A2183-DBC.html" >More >></a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2> Experimental Instruments and Equipments</h2> <ul> <li><a href="/P7052-Automatic-Nucleic-Acid-Extraction-System.html" >Automatic Nucleic Acid Extraction System</a></li> <li><a href="/P7052-Automatic-Nucleic-Acid-Extraction-System.html" >More >></a></li> </ul> </div> </div> </div> </li> <div class="layui-menu-body-titleA"> Search by Modality </div> <li class="layui-menu-item-parent" > <div class="layui-menu-body-title upA"> <a href="/A2471-Cell-_Therapy-_Solutions.html">Cell Therapy </a><i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_1" > <div class="layui-menu-body-title layui-menu-body-title2"> Cell Therapy </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow" > <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_a.jpg" alt="Discovery &amp; Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>CAR Targets</h2> <ul> <li><a href="/A1088-CD19%EF%BC%9Aa-validated-therapeutic-target-for-B-cell-malignancies.html" >CD19 Protein</a></li> <li><a href="/search-keywords-BCMA-molecule-36-w-mo36.html" >BCMA Protein</a></li> <li><a href="/search-keywords-MSLN.html" >MSLN Protein</a></li> <li><a href="/A1971-Hematological-Malignancies.html" >Hematologica Malignancies CAR Targets</a></li> <li><a href="/A1861-Solid-Tumor-CAR-Targets.html" >Solid Tumor CAR Targets</a></li> <li><a href="/A1041-Targets-of-CAR-T-Cell-Therapy.html" >More Targets >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Universal CAR Detection Tool</h2> <ul> <li><a href="/search-keywords-G4S%20Linker.html" >Anti-G4S linker Antibody</a></li> <li><a href="/L-422-Protein%20L.html" >Protein L</a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Target Proteins</h2> <ul> <li><a href="/A1656-MHC-Class-I-Complex-Custom-Service.html" >MHC-peptide Complexes</a></li> <li><a href="/A1536-Proteins-for-Neuroscience.html" >Aneuro - Proteins for Neuroscience</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>General Proteins</h2> <ul> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA Series Products</a></li> </ul> </div> <div class="pane_box_link"> <h2>Drug Screening Service</h2> <ul> <li><a href="/A1151-SPR-BLI-analytical-service.html" >SPR /BLI analytical service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics Development</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cell Culture Products</h2> <ul> <li><a href="/A1798-cell-culture-cytokines.html" >Cell Culture Growth Factors & Antibodies</a></li> <li><a href="/A2660-T-cell-culture-media.html" >CelThera™ GMP T Cell Expansion Medium</a></li> <li><a href="/A1595-ActiveMax®-Cytokines.html" >ActiveMax Cell Activation Beads</a></li> <li><a href="/A2560-ECMproteins.html" >Extracellular Matrix (ECM) Proteins</a></li> <li><a href="/A2097-iPSC-Culturing.html" >CMC Production Process of iPSC-based Cell Therapy</a></li> <li><a href="/A2612-Laminin.html" >Laminin Proteins for Clinical iPSC Banking</a></li> <li><a href="/A1904-Organoid-Culture.html" >Cytokines for Organoid Culture</a></li> <li><a href="/A1813-Neural-Factors.html" >Aneuro - Neural Factors</a></li> <li><a href="/A2495-TcellCMC.html" >CMC Production Process of Adoptive T Cell Therapies</a></li> </ul> </div> <div class="pane_box_link"> <h2>Premium(Pre-GMP) grade Raw Materials</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >Premium(Pre-GMP) Growth Factors</a></li> <li><a href="/P5481-GMP-Monoclonal-Anti-Human-CD3-Antibody-%28OKT3%29-DMF-Filed.html" >GMP Grade Antibodies</a></li> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP Grade GENIUS™Nuclease </a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> <li><a href="/A1595-ActiveMax®-Cytokines.html" >ActiveMax Cell Activation Beads</a></li> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >Key Raw Materials for CGT</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal Products</h2> <ul> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP Grade GENIUS™Nuclease </a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> <div class="pane_box_link"> <h2>Gene Editing Products</h2> <ul> <li><a href="/A1657-CRISPR-Cas-technology.html" >GENPower - Cas Enzymes</a></li> <li><a href="/A1301-enzyme-products.html#mRNA_enzymeA" >mRNA Synthesis Enzymes</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Large-Scale Manufacturing</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >GMP-grade Raw Materials</a></li> <li><a href="/A1888-Custom-GMP-Services.html" >GMP Protein Services</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_c.jpg" alt="CMC-Quality Control"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" target="_blank" >Residual Host Cell DNA / RNA Detection Kits</a></li> <li><a href="/search-keywords-Activity.html" target="_blank" >RNase / DNase Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" target="_blank" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/P7814-resDetect%E2%84%A2-BSA-ELISA-Kit.html" target="_blank" >Residual BSA ELISA Kit</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html#pro" target="_blank" >Residual Cell Culture Materials Detection Kits</a></li> <li><a href="/P6991-resDetect%E2%84%A2-Kanamycin-ELISA-Kit.html" target="_blank" >Residual Antibiotics Detection Kits</a></li> <li><a href="/P7281-resDetect%E2%84%A2-HIV-1-p24-ELISA-Kit-%28Residue-Testing%29.html" target="_blank" >Residual HIV-1 p24 ELISA Kit</a></li> <li><a href="/search-keywords-Mycoplasma.html" target="_blank">Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" target="_blank">Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="/A2504-resDetect-CGT.html" target="_blank" >CGT CMC Manufacturing Process Residue Detection Solutions</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>CAR Detection Tools</h2> <ul> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/L-1788-G4S%C2%A0linker.html" >Anti-G4s Linker Antibody</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >ComboX Isotype Controls</a></li> </ul> </div> <div class="pane_box_link"> <h2>Potency Assays</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line - CellInsight</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Pre-clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_d.jpg" alt="Preclinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/L-1788-G4S%C2%A0linker.html" >Anti-G4s Linker Antibody</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Pharmacodynamics Studies</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li><li><a href="/A1904-Organoid-Culture.html" >Organoid Culture Cytokines</a></li> <li><a href="/A1718-Pre-formed-Fibrils-(PFFs).html" >Pre-formed Fibrils (Aneuro)</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2183-DBC.html" >Diagnostic Biochips</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/P5420-Anti-CD19-%28FMC63%29-CAR-Immunogenicity-ELISA-Kit.html" >Immunogenicity Anti-FMC63 ELISA kit</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Audit & Documentation support</h2> <ul> <li><a href="/A1148-FDA-DMF-Filed-Proteins.html" >FDA DMF Filed Proteins</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html" >GMP Regulatory Support Files</a></li> </ul> </div> <div class="pane_box_link"> <h2>Companion Diagnostics Tools</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_5 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_e.jpg" alt="Clinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/L-1788-G4S%C2%A0linker.html" >Anti-G4s Linker Antibody</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/P5420-Anti-CD19-%28FMC63%29-CAR-Immunogenicity-ELISA-Kit.html" >Immunogenicity Anti-FMC63 ELISA kit</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> </ul> </div> </div> </div> </li> </ul> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title upA"> Gene Therapy <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_2"> <div class="layui-menu-body-title layui-menu-body-title2"> Gene Therapy </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_a.jpg" alt="Discovery &amp; Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Gene Editing</h2> <ul> <li><a href="/A1657-CRISPR-Cas-technology.html" >GENPower - Cas Enzymes</a></li> </ul> </div> <div class="pane_box_link"> <h2>AAV Titer Quantitation</h2> <ul> <li><a href="/P7031-AAV5-Titration-ELISA-Kit-%28Fast%29.html" >AAV5 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7157-AAV5-Titration-ELISA-Kit.html" >AAV5 Titration ELISA Kit </a></li> <li><a href="/P7823-AAV3-Titration-ELISA-Kit-%28Fast%29.html" >AAV3 Titration ELISA Kit (Fast) </a></li> <li><a href="/P7100-AAV3-Titration-ELISA-Kit.html" >AAV3 Titration ELISA Kit</a></li> <li><a href="/P7735-AAV8-Titration-ELISA-Kit-%28Fast%29.html" >AAV8 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7736-AAV8-Titration-ELISA-Kit.html" >AAV8 Titration ELISA Kit</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Premium(Pre-GMP) grade Raw Materials</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >Premium(Pre-GMP) Growth Factors</a></li> </ul> </div> <div class="pane_box_link"> <h2>Gene Editing Products</h2> <ul> <li><a href="/A1657-CRISPR-Cas-technology.html" >GENPower - Cas Enzymes</a></li> <li><a href="/A1301-enzyme-products.html#mRNA_enzymeA" >mRNA Synthesis Enzymes</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal Products</h2> <ul> <li><a href="/L-1211-Nuclease.html" >Nucleic Acid Removal</a> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> <div class="pane_box_link"> <h2>AAV Titer Quantitation</h2> <ul> <li><a href="/P7031-AAV5-Titration-ELISA-Kit-%28Fast%29.html" >AAV5 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7157-AAV5-Titration-ELISA-Kit.html" >AAV5 Titration ELISA Kit </a></li> <li><a href="/P7823-AAV3-Titration-ELISA-Kit-%28Fast%29.html" >AAV3 Titration ELISA Kit (Fast) </a></li> <li><a href="/P7100-AAV3-Titration-ELISA-Kit.html" >AAV3 Titration ELISA Kit</a></li> <li><a href="/P7735-AAV8-Titration-ELISA-Kit-%28Fast%29.html" >AAV8 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7736-AAV8-Titration-ELISA-Kit.html" >AAV8 Titration ELISA Kit</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Large-Scale Manufacturing</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >GMP-grade Raw Materials</a></li> <li><a href="/A1888-Custom-GMP-Services.html" >GMP Protein Services</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_c.jpg" alt="CMC-Quality Control" width="100%"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" target="_blank" >Residual Host Cell DNA / RNA Detection Kits</a></li> <li><a href="/search-keywords-Activity.html" target="_blank" >RNase / DNase Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" target="_blank" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/P7814-resDetect%E2%84%A2-BSA-ELISA-Kit.html" target="_blank" >Residual BSA ELISA Kit</a></li> <li><a href="/P6991-resDetect%E2%84%A2-Kanamycin-ELISA-Kit.html" target="_blank" >Residual Antibiotics Detection Kits</a></li> <li><a href="/A2504-resDetect-CGT.html" target="_blank" >CGT CMC Manufacturing Process Residue Detection Solutions</a></li> <li><a href="/search-keywords-Mycoplasma.html" target="_blank">Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" target="_blank">Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Potency Assays</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> </ul> </div> <div class="pane_box_link"> <h2>AAV Titer Quantitation</h2> <ul> <li><a href="/P7031-AAV5-Titration-ELISA-Kit-%28Fast%29.html" >AAV5 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7157-AAV5-Titration-ELISA-Kit.html" >AAV5 Titration ELISA Kit </a></li> <li><a href="/P7823-AAV3-Titration-ELISA-Kit-%28Fast%29.html" >AAV3 Titration ELISA Kit (Fast) </a></li> <li><a href="/P7100-AAV3-Titration-ELISA-Kit.html" >AAV3 Titration ELISA Kit</a></li> <li><a href="/P7735-AAV8-Titration-ELISA-Kit-%28Fast%29.html" >AAV8 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7736-AAV8-Titration-ELISA-Kit.html" >AAV8 Titration ELISA Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Pre-clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_d.jpg" alt="Preclinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacodynamics Studies</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li><li><a href="/A1904-Organoid-Culture.html" >Organoid Culture Cytokines</a></li> <li><a href="/A1718-Pre-formed-Fibrils-(PFFs).html" >Pre-formed Fibrils (Aneuro)</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2183-DBC.html" >Diagnostic Biochips</a></li> </ul> </div> <div class="pane_box_link"> <h2>Security Studies</h2> <ul> <li><a href="/search-keywords-AAV%20antibody%20kit.html" >Anti-AAV Antibody ELISA Kit</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> <div class="pane_box_link"> <h2>Audit & Documentation support</h2> <ul> <li><a href="/A1148-FDA-DMF-Filed-Proteins.html" >FDA DMF Filed Proteins</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html" >GMP Regulatory Support Files</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics Tools</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_5 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_e.jpg" alt="Clinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> <div class="pane_box_link"> <h2>Security Studies</h2> <ul> <li><a href="/search-keywords-AAV%20antibody%20kit.html" >Anti-AAV Antibody ELISA Kit</a></li> </ul> </div> </div> </div> </li> </ul> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title upA"> <a href="/A2356-Therapeutic-Antibody-Page.html" >Therapeutic Antibodies </a><i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_3"> <div class="layui-menu-body-title layui-menu-body-title2"> Therapeutic Antibodies </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_a.jpg" alt="Discovery &amp; Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Target Proteins</h2> <ul> <li><a href="/A1288-Cytokine.html" >Cytokine Targets</a></li> <li><a href="/A974-Immune-Checkpoint-Proteins.html" >Checkpoint Proteins</a></li> <li><a href="/A2117-Agonist-Target-Proteins.html" >Agonist</a></li> <li><a href="/A1290-Transmembrane-Proteins-Platform.html" >FLAG</a></li> <li><a href="/A1536-Proteins-for-Neuroscience.html" >Aneuro</a></li> <li><a href="/A1265-Tumor-microenvironment.html" >Tumor Microenvironment</a></li> <li><a href="/A1222-Bispecific-antibody-targets-and-more.html" >Bispecifc Antibody Targets</a></li> <li><a href="/A1656-MHC-Class-I-Complex-Custom-Service.html" >MHC Complexes</a></li> </ul> </div> <div class="pane_box_link"> <h2>Antibody Screening</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1096-Inhibitor-Screening-Kits.html" >Inhibitor Screening Kits</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining Fluorescent Labeled Proteins</a></li> <li><a href="/A1128-Pre-Coupling-Magnetic-Beads.html" >Pre-coupled Magnetic Beads</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1969-Recombinant-Antibody-Services.html" >Recombinant Antibody Expression Services</a></li> <li><a href="/A1151-SPR-BLI-analytical-service.html" >SPR /BLI analytical service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Fc Proteins</h2> <ul> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Fc Proteins</a></li> <li><a href="/A712-Fc-Receptor-Proteins.html" >Fc Receptor</a></li> <li><a href="/A1394-FcRn%EF%BC%88Neonatal-Fc-Receptor%EF%BC%89.html" >Neonatal Fc Receptor</a></li> <li><a href="/P7366-Human-FcRn-binding-Kit-%28TR-FRET%29.html" >FcRn Binding Kit</a></li> </ul> </div> <div class="pane_box_link"> <h2>Cell Line (CellInsight)</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal</h2> <ul> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP GENIUS Nuclease</a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_c.jpg" alt="CMC-Quality Control"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" >Host DNA/Protein Quantitative Kits</a></li> <li><a href="/P7433-resDetect%E2%84%A2-Universal-Protein-A-Quick-ELISA-Kit-%28Boiling-free%29.html" >Residual Affinity Ligands Detection Kits</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html#pro" >Residual Cell Culture Materials Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/P6991-resDetect%E2%84%A2-Kanamycin-ELISA-Kit.html" >Residual Antibiotics Detection Kits</a></li> <li><a href="/A2543-resDetect-Antibody.html" >Therapeutic antibodies CMC Manufacturing Process Residue Detection Solutions</a></li> <li><a href="/search-keywords-Mycoplasma.html" >Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" >Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Quality Control Products</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Isotype Control</a></li> <li><a href="/A2154-Tool-enzymes.html" >Enzymes for Antibody Characterization Analysis</a></li> <li><a href="/A1794-MALS-UNcle-Platform.html" >Quality Characterization Analytical Services</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cytokine Release Detection</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine ELISA Kits</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Preclinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_d.jpg" alt="Preclinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1089-Anti-idiotypic-Antibodies.html" >Anti-idiotypic Antibodies</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1078-ELISA-Assay-Kits-for-Therapeutic-Antibodies.html" >PK ELISA Assays</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic & ADA Assay Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Pharmacodynamics Studies</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li><li><a href="/A1904-Organoid-Culture.html" >Organoid Culture Cytokines</a></li> <li><a href="/A1718-Pre-formed-Fibrils-(PFFs).html" >Pre-formed Fibrils (Aneuro)</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2183-DBC.html" >Diagnostic Biochips</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Audit & Documentation support</h2> <ul> <li><a href="/A1148-FDA-DMF-Filed-Proteins.html" >FDA DMF Filed Proteins</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html" >GMP Regulatory Support Files</a></li> </ul> </div> <div class="pane_box_link"> <h2>Companion Diagnostics Tools</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_5 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_e.jpg" alt="Clinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1089-Anti-idiotypic-Antibodies.html" >Anti-idiotypic Antibodies</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1078-ELISA-Assay-Kits-for-Therapeutic-Antibodies.html" >PK ELISA Assays</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody ADA Development Service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> </div> </div> </li> </ul> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title upA"> Antibody Drug Conjugates <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_4"> <div class="layui-menu-body-title layui-menu-body-title2"> Antibody Drug Conjugates </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightD_a.jpg" alt="Discovery &amp; Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Target Proteins</h2> <ul> <li><a href="/A1210-Targets-for-Antibody-Drug-Conjugates.html#module=kit1" >ADC Drug Targets</a></li> <li><a href="/A1288-Cytokine.html" >Cytokine Targets</a></li> <li><a href="/A974-Immune-Checkpoint-Proteins.html" >Checkpoint Proteins</a></li> <li><a href="/A2117-Agonist-Target-Proteins.html" >Agonist</a></li> <li><a href="/A1290-Transmembrane-Proteins-Platform.html" >FLAG</a></li> <li><a href="/A1536-Proteins-for-Neuroscience.html" >Aneuro</a></li> <li><a href="/A1265-Tumor-microenvironment.html" >Tumor Microenvironment</a></li> <li><a href="/A1222-Bispecific-antibody-targets-and-more.html" >Bispecifc Antibody Targets</a></li> <li><a href="/A1656-MHC-Class-I-Complex-Custom-Service.html" >MHC Complexes</a></li> </ul> </div> <div class="pane_box_link"> <h2>Antibody Screening</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1096-Inhibitor-Screening-Kits.html" >Inhibitor Screening Kits</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining Fluorescent Labeled Proteins</a></li> <li><a href="/A1128-Pre-Coupling-Magnetic-Beads.html" >Pre-coupled Magnetic Beads</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1969-Recombinant-Antibody-Services.html" >Recombinant Antibody Expression Services</a></li> <li><a href="/A1151-SPR-BLI-analytical-service.html" >SPR /BLI analytical service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Fc Proteins</h2> <ul> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Fc Proteins</a></li> <li><a href="/A712-Fc-Receptor-Proteins.html" >Fc Receptor</a></li> <li><a href="/A1394-FcRn%EF%BC%88Neonatal-Fc-Receptor%EF%BC%89.html" >Neonatal Fc Receptor</a></li> <li><a href="/P7366-Human-FcRn-binding-Kit-%28TR-FRET%29.html" >FcRn Binding Kit</a></li> </ul> </div> <div class="pane_box_link"> <h2>ADC Reagents</h2> <ul> <li><a href="/A2584-ADC-Conjugation-Kit.html" >AGLink Conjugation Kit</a></li> <li><a href="/A1210-Targets-for-Antibody-Drug-Conjugates.html" >Proteases for Peptide Linker</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cell Line (CellInsight)</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> <div class="pane_box_link"> <h2>Companion Diagnostics</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightD_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal</h2> <ul> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP GENIUS Nuclease</a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> <div class="pane_box_link"> <h2>Conjugation Kits</h2> <ul> <li><a href="/A2584-ADC-Conjugation-Kit.html" >AGLink Conjugation Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightD_c.jpg" alt="CMC-Quality Control"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" >Host DNA/Protein Quantitative Kits</a></li> <li><a href="/P7433-resDetect%E2%84%A2-Universal-Protein-A-Quick-ELISA-Kit-%28Boiling-free%29.html" >Residual Affinity Ligands Detection Kits</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html#pro" >Residual Cell Culture Materials Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/search-keywords-Mycoplasma.html" >Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" >Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Quality Control Products</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Isotype Control</a></li> <li><a href="/A2154-Tool-enzymes.html" >Enzymes for Antibody Characterization Analysis</a></li> <li><a href="/A1794-MALS-UNcle-Platform.html" >Quality Characterization Analytical Services</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>ADC Payload Evaluation</h2> <ul> <li><a href="/A2226-Anti-payload-antibodies.html" >Anti-payload Antibodies</a></li> </ul> </div> <div class="pane_box_link"> <h2>Antibody Enzymes</h2> <ul> <li><a href="/A1301-enzyme-products.html" >Antibody Characterization</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cytokine Release Detection</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine ELISA Kits</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Pre-clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" 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font-style:italic; text-align:center !important;">Fig 1. Schematic diagram of IL-4/IL-4R signaling pathway. </em> </div> <div class="layui-col-md8"> <p class="public_text_dec" style="margin-top:35px; text-align: justify;">Interleukin-4Rα (<a style="color:#cc3500;text-decoration: underline;" target="_blank" href="/search-keywords-IL_4%20R%20alpha.html?">IL-4Rα</a>), the key receptor of IL-4, has emerged as an ‘inspiring’ target for innovative therapies aimed at treating various inflammatory and oncological diseases. IL-4Rα is a type I transmembrane protein that plays a key role in the molecular pathway that drives a specific immune pattern called type II inflammations. </p> <p class="public_text_dec" id="Platform" style="margin-top:35px; text-align: justify;">This pathway is driven by two cytokines: interleukin-4 (<a style="color:#cc3500;text-decoration: underline;" target="_blank" href="/L-323-IL-4.html">IL-4</a>) and interleukin-13 (<a style="color:#cc3500;text-decoration: underline;" target="_blank" href="/L-537-IL-13.html">IL-13</a>). Both cytokines have diverse biological and immunological effects on lymphocytes, dendritic cells and fibroblasts adjustment function. Specifically, these cytokines bind to IL-4Rα to initiate the type II inflammation pathway that includes differentiation of Th2 cells, airway inflammation and mucus production. </p> </div> </div> </div> <div class="clear"></div> <!--CLINICAL APPLICATION --> <div class="productSection"> <div class="productTit" style="margin-top: -25px;"> Clinical Application </div> <p class="public_text_dec">IL-4R and cytokines IL-4 and IL-13 are key regulators in humoral and adaptive immunity. This means that an imbalance in either receptor expression or circulating signaling cytokines can be clinically observed. The resultant immune overreaction is initiated by an initial imbalance of TH1 and TH2 differentiation that drives an abnormal secretion of cytokines. Activated Th2 cells release cytokines including IL-4, 13, and 31, which activate downstream B cells to transform and produce immunoglobulin E (IgE) antibodies. In turn, mast cells and basophils are recruited to degranulate and produce inflammatory factors. Simultaneously, the secreted IL-4 and 13 continue to bind to its respective receptors (e. g. IL-4R) that repeatedly promotes TH2 differentiation and subsequent inflammation. This effect is observed through several autoimmune diseases including asthma, eczema, and hay fever, as well as in metastatic tumors. </p> <div class="topExplain"> <div class="layui-row layui-col-space30"> <div class="layui-col-md3"> <div class="topPic"> <div class="picTitle center"> Asthma</div> <div class="picImg imgOpen center"> <img src="/static/main/images/Product-IL_4/IL-4_2.jpg" height="200px" data-category="Asthma" alt="Asthma"> </div> <div class="public_text_dec">Asthma is a complex, persistent, and lifelong inflammatory disease. Dupilumab is a human monoclonal antibody targeting IL-4Rα. Its mechanism of action is to specifically block the type II IL-4R/IL-13R signaling pathway while inhibiting the intracellular activity of IL-4 and IL-13 with STAT6. By preventing cytokine signaling at the source, the Th2 inflammatory response is minimized. </div> </div> </div> <div class="layui-col-md3"> <div class="topPic"> <div class="picTitle center">Eczema</div> <div class="picImg imgOpen center"> <img src="/static/main/images/Product-IL_4/IL-4_3.jpg" height="200px" data-category="Eczema" alt="Eczema"> </div> <div class="public_text_dec">Eczema, otherwise known as atopic dermatitis, is a disease characterized by skin inflammation, dry skin, rashes, and blisters. Recent studies have begun to emphasize that eczema may stem from overexpression of IL-13/IL-4 signaling in specific individuals. Thus, development of therapies targeting the IL-13/IL-4 /IL-4R and its intracellular signaling pathway is a promising innovative strategy. </div> </div> </div> <div class="layui-col-md3"> <div class="topPic"> <div class="picTitle center">Hay Fever</div> <div class="picImg imgOpen center"> <img src="/static/main/images/Product-IL_4/IL-4_4.jpg" height="200px" data-category="Hay Fever" alt="Hay Fever"> </div> <div class="public_text_dec">Hay fever, also known as allergic rhinitis, is a common chronic disease that is driven by an IgE mediated inflammatory response in the nasal mucosa and cause a variety of complications. In a recent study, inhibition of the IL-4/STAT6/GATA3 signaling pathway can reduce IL-4 secretion, serum IgE and airway mucus production, effectively improving symptoms due to hay fever. </div> </div> </div> <div class="layui-col-md3"> <div class="topPic"> <div class="picTitle center">Metastatic Tumors</div> <div class="picImg imgOpen center"> <img src="/static/main/images/Product-IL_4/IL-4_5.jpg" width="95%" height="200px" data-category="Metastatic Tumors" alt="Metastatic Tumors"> </div> <div class="public_text_dec">Beyond autoimmune diseases, IL-4R is also overexpressed in many epithelial cancers. Whereas the intracellular signaling of IL-4/ IL-4R in lymphocytes drives the type II inflammation pathway. As such, overexpression of IL-4R drives metastasis and tumor growth, revealing IL-4R inhibitory drugs as a potential therapeutic tool for metastatic tumors. </div> </div> </div> </div> </div> </div> <div class="clear"></div> <div class="productSection"> <div class="productTit"> Product Features </div> <div class="s-con cf"> <div class="layui-col-space10 " style="float: left;width: 100%;"> <div class="layui-col-md6"> <p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20" /><strong>Native conformation, free protocol shared</strong></p> <p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20" /><strong>High biological activity verified by ELISA/SPR/ BLI</strong></p> <p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20" /><strong>Authentic structure verified by SEC-MALS</strong></p> </div> <div class="layui-col-md6"> <p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20" /><strong>Comprehensive products with various tags and species</strong></p> <p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20" /><strong>High purity verified by SDS-PAGE</strong></p> </div> </div> </div> </div> <div class="clear"></div> <!-- PRODUCT LIST --> <div class="productSection" id="pro"> <div class="productTit"> Product List </div> <table class="public_table layui-table pro_table pro_table_box"> <thead> <tr> <th>Molecule</th> <th>Cat. No.</th> <th>Species</th> <th>Product Description</th> <th>Preorder/Order</th> </tr> </thead> <tbody id="auto_il4"></tbody> </table> </div> <div class="clear"></div> <!-- SEARCH ALL RELATED TARGET PROTEINS --> <div class="productSection"> <div class="productTit"> Search All Related Target Proteins </div> <div class="productList"> <a href="/L-323-IL-4.html" target="_blank">IL-4</a> <a href="/L-537-IL-13.html" target="_blank">IL-13</a> <a href="/search-keywords-IL_13%20R%20alpha.html?" target="_blank">IL-13 R alpha</a> </div> </div> <div class="clear"></div> <div class="productSection"> <div class="productTit"> Verification Data </div> <div class="public_img_text_box public_img_l_r layui-col-space12 "> <div class="layui-col-md6" style="padding:20px;"> <div class="h3-title"> High purity (>95%) verified by SDS-PAGE </div> <div class="imgBox imgOpen"> <img style="height:210px;" src="/static/main/images/Product-IL_4/IL_4_1.jpg" class="facs_img" data-category="ILR-H5253" alt="ILR-H5253"> </div> <p class="imgText"> <em>HumanI IL-4 R alpha, Fc Tag (Cat. No. <a target="_blank" href="/P2728-Human-IL-4-R-alpha--CD124-Protein-Fc-Tag-%28MALS-verified%29.html">ILR-H5253</a>)on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than <span style="color: #cc3536;">95%</span></em></p> </div> <div class="layui-col-md6" style="padding:20px;"> <div class="h3-title"> High structural homogeneity (>90%) verified by SEC-MALS </div> <div class="imgBox imgOpen"> <img style="height:210px;" src="/static/main/images/Product-IL_4/IL_4_2.jpg" class="facs_img" data-category="IL4-C5259" alt="IL4-C5259"> </div> <p class="imgText"> <em>The purity of Cynomolgus IL-4, Fc Tag (Cat. No.<a target="_blank" href="/P4770-Cynomolgus-IL-4-Protein-Fc-Tag-%28MALS-verified%29.html"> IL4-C5259</a>) is more than<span style="color: #cc3536;">90%</span>and the molecular weight of this protein is around<span style="color: #cc3536;">85-115 kDa</span>verified by SEC-MALS.</em></p> </div> </div> <div class="clear"></div> <h3 class="h3-title"> High biological activity verified by ELISA</h3> <div class="clear"></div> <div class="public_img_text_box public_img_l_r layui-col-space12 "> <div class="layui-col-md6" style="padding:20px;"> <div class="imgBox imgOpen"> <img style="height:310px;" src="/static/main/images/Product-IL_4/IL_4_3.jpg" class="facs_img" data-category="IL4-H4218" alt="IL4-H4218"> </div> <p class="imgText"> <em>Immobilized ActiveMax® Human IL-4, Tag Free (Cat. No. <a target="_blank" href="/P297-ActiveMax%AE-Human-IL-4-Protein-Tag-Free.html">IL4-H4218</a>)at 5 μL/mL (100 μL/well) can bind Biotinylated Human IL-4 R alpha, Avitag,His Tag (Cat. No.<a target="_blank" href="/P2222-Biotinylated-Human-IL-4-R-alpha--CD124-Protein-Avitag%E2%84%A2His-Tag-%28MALS-verified%29.html"> ILR-H82E9</a>) with a linear range of 2-78 ng/mL.</em></p> <center> <label class="btn_protocol tab_btn_protocol des_protocol"><a data-sign="IL4-H4218" style="color:#FFFFFF">Protocol</a> </center> </div> <div class="layui-col-md6" style="padding:20px;"> <div class="imgBox imgOpen"> <img style="height:310px;" src="/static/main/images/Product-IL_4/IL_4_4.jpg" class="facs_img" data-category="IL4-H4218" alt="IL4-H4218"> </div> <p class="imgText"> <em>Immobilized ActiveMax® Human IL-4, Tag Free(Cat. No. <a target="_blank" href="/P297-ActiveMax%AE-Human-IL-4-Protein-Tag-Free.html"> IL4-H4218</a>)at 5 μg/mL (100 μL/well) can bind Human IL-4 R alpha, Fc Tag (Cat. No.<a target="_blank" href="/P2728-Human-IL-4-R-alpha--CD124-Protein-Fc-Tag-%28MALS-verified%29.html"> ILR-H5253</a>) with a linear range of 1-20 ng/mL.</em></p> <center> <label class="btn_protocol tab_btn_protocol des_protocol"><a data-sign=" IL4-H4218" style="color:#FFFFFF">Protocol</a> </center> </div> </div> <div class="clear"></div> <h3 class="h3-title">Affinity verified by SPR and BLI</h3> <div class="clear"></div> <div class="public_img_text_box public_img_l_r layui-col-space12 "> <div class="layui-col-md6" style="padding:20px;"> <div class="imgBox imgOpen"> <img style="height:310px;" src="/static/main/images/Product-IL_4/IL_4_5.jpg" class="facs_img" data-category="IL1-H82E8" alt="IL1-H82E8"> </div> <p class="imgText"> <em>Biotinylated Human IL-13 R alpha 1 Protein, His,Avitag (Cat. No. <a target="_blank" href="/P4720-Biotinylated-Human-IL-13-R-alpha-1-Protein-HisAvitag%E2%84%A2-%28MALS-verified%29.html">IL1-H82E8</a>) captured on Biotin CAP-Series S Sensor Chip can bind Human IL-13, His Tag (Cat. No.<a target="_blank" href="/P2895-Human-IL-13-Protein-His-Tag.html">IL3-H52H4</a>) with an affinity constant of 34.4 nM as determined in a SPR assay (Biacore 8K)</em></p> <center> <label class="btn_protocol tab_btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="IL1-H82E8">Protocol</a> </center> </div> <div class="layui-col-md6" style="padding:20px;"> <div class="imgBox imgOpen"> <img style="height:310px;" src="/static/main/images/Product-IL_4/IL_4_6.jpg" class="facs_img" data-category="IL3-H82E5" alt="IL3-H82E5"> </div> <p class="imgText"> <em>Loaded Biotinylated Human IL-13, His,Avitag (Cat. No. <a target="_blank" href="/P3034-Biotinylated-Human-IL-13-Protein-HisAvitag%E2%84%A2.html">IL3-H82E5</a>) on SA Biosensor, can bind Human IL-13 R alpha 2, His Tag (Cat. No.<a target="_blank" href="/P2896-Human-IL-13-R-alpha-2-Protein-His-Tag-%28MALS-verified%29.html">IL2-H52H5</a>) with an affinity constant of 6.31 nM as determined in BLI assay (ForteBio Octet Red96e).</em></p> <center> <label class="btn_protocol tab_btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="IL3-H82E5">Protocol</a> </center> </div> </div> </div> <div class="clear"></div> <!-- INFORMATION --> <div class="productSection"> <h3 class="h3-title"> Related Information </h3> <p style="color: #cc3536; margin-bottom: 10px;font-weight: bold">>>> <a href="/A1746-IL-4R-Alpha-a-Potential-Drug-Target.html" target="_blank" style="font-weight: bold;color: #cc3536; text-decoration: underline;font-size: 14px;">[Inspiring Target] IL-4R Alpha, a Potential Drug Target Worth over $10 Billion</a></p> </div> <div class="clear"></div> <!-- REFERENCE --> <div class="productSection" id="literature"> <div class="h3-title" style="margin-top:10px;"> Reference </div> <div class="referList"> <ul> <li>[1] Weng, S. Y., Wang, X., Vijayan, S., Tang, Y., Kim, Y. O., Padberg, K., ... & Schuppan, D. (2018). IL-4 receptor alpha signaling through macrophages differentially regulates liver fibrosis progression and reversal. EBioMedicine, 29, 92-103.https://doi.org/10.1016/j.ebiom.2018.01.028.</li> <li>[2] Husna, S. M. N., Shukri, N. M., Ashari, N. S. M., & Wong, K. K. (2022). IL-4/IL-13 axis as therapeutic targets in allergic rhinitis and asthma. PeerJ, https://doi.org/10, e13444.10.7717/peerj.13444.</li> <li>[3] Liang, K. L., Yu, S. J., Huang, W. C., & Yen, H. R. (2020). Luteolin attenuates allergic nasal inflammation via inhibition of interleukin-4 in an allergic rhinitis mouse model and peripheral blood from human subjects with allergic rhinitis. Frontiers in pharmacology, 11, 291.https://doi.org/10.3389/fphar.2020.00291.</li> <li>[4] Bankaitis, K. V., & Fingleton, B. (2015). Targeting IL4/IL4R for the treatment of epithelial cancer metastasis. Clinical & experimental metastasis, 32(8), 847-856.https://doi.org/10.1007/s10585-015-9747-9. </li> <li>[5] Moran, A., & Pavord, I. D. (2020). Anti-IL-4/IL-13 for the treatment of asthma: The story so far. Expert Opinion on Biological Therapy, 20(3), 283-294.</li> <li>https://doi.org/10.1080/14712598.2020.1714027.</li> <li>[6] Furue, M. (2020). Regulation of skin barrier function via competition between AHR axis versus IL-13/IL-4‒JAK‒STAT6/STAT3 axis: pathogenic and therapeutic implications in atopic dermatitis. Journal of Clinical Medicine, 9(11), 3741.https://doi.org/10.3390/jcm9113741.</li> <li>[7] Pelaia, C., Pelaia, G., Crimi, C., Maglio, A., Armentaro, G., Calabrese, C., ... & Vatrella, A. (2022). Biological Therapy of Severe Asthma with Dupilumab, a Dual Receptor Antagonist of Interleukins 4 and 13. Vaccines, 10(6), 974.https://doi.org/10.3390/vaccines10060974.</li> </ul> </div> </div> </div> <style> .btn_protocol { width: 130px !important; background-color: #cc3536; line-height: 25px; text-align: center; height: 25px; color: #fff; border-radius: 6px; margin-top: 4px; display: inline-block; } .fd_left_box { width: 200px; font-size: 1.7em; font-weight: bold; color: #cc3536 !important; line-height: 28px; margin: 36px 12px; display: block; text-align: center; } .fd_left { width: 240px; height: 196px; margin: 20px auto; background: url(https://www.acrobiosystems.com/static/main/images/Neural_target/neuralbg.png) no-repeat; background-size: auto; background-size: cover; position: fixed; left: 0; bottom: 5%; } </style> <style> .center { text-align: center; } .show_report { width: 130px !important; } .productLink .box a { line-height: 60px !important; height: 60px; } .tab_btn_protocol { width: 100px; background-color: #cc3536; line-height: 25px; height: 25px; color: #fff; border-radius: 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height:auto !important;} .contEurope a{display:inline; color:#a1a1a1; line-height:24px;} /*.embeddedServiceHelpButton .helpButton .uiButton { font-family: Verdana, Geneva, sans-serif; font-size: 12px; max-width:28em; height:32px; }*/ /*初始化按钮样式 start */ .embeddedServiceHelpButton .helpButton .uiButton { /*去掉按钮边框*/ background-color: transparent; box-shadow:none; min-width:100px;; max-width:100px; height:100px; background: url(https://www.acrobiosystems.com/static/main/images/ce_icon.png); background-size: 100px; border: 1px solid transparent; } .embeddedServiceHelpButton .helpButton .uiButton:hover { border:0 !important; outline:none !important; -webkit-appearance: none !important; background-color: none !important; box-shadow: none !important; /*图片放大 数字是多少倍。默认是1*/ transform: scale(1.2) !important; } .embeddedServiceHelpButton .helpButton .uiButton .helpButtonLabel { display: none; } .embeddedServiceHelpButton .embeddedServiceIcon::before { content: none; } /* 去除鼠标悬停按钮时背景图片的阴影 */ .embeddedServiceHelpButton .helpButton .helpButtonEnabled:hover::before, .embeddedServiceHelpButton .helpButton .helpButtonEnabled:focus::before { background-color: transparent !important; box-shadow: none !important; } .embeddedServiceHelpButton .helpButton { height:100px; } /*初始化按钮样式 End */ .embeddedServiceSidebarMinimizedDefaultUI { min-width:180px; max-width:180px; height:40px; } .embeddedServiceSidebarButton { border-radius: 20px; background-color: #C43334; width:80%; height:40px; } .message{ background-color:#C43334; border-style:none; color:#fff; } .embeddedServiceSidebarFormField .uiInput .uiLabel-left{ font-family: Verdana, Geneva, sans-serif; font-weight: bold; color:#666; line-height:2.25; } .embeddedServiceSidebarFormField .uiInput .required { left: -10px; top: -4px; } [embeddedService-chatHeader_chatHeader-host] { height:45px; min-height:45px; } .embeddedServiceSidebarFormField .slds-style-inputtext, .embeddedServiceSidebarFormField .slds-style-select { height:31px; font-family: Verdana, Geneva, sans-serif; } </style> <script src="https://service.force.com/embeddedservice/5.0/esw.min.js" type="text/javascript"> </script> <script type="text/javascript"> var initESW = function(gslbBaseURL, onlineChatuserInfo) { embedded_svc.settings.autoOpenPostChat = true; embedded_svc.settings.displayHelpButton = true; embedded_svc.settings.language = 'en'; embedded_svc.settings.defaultMinimizedText = 'Online - Welcome to ACROBiosystems'; embedded_svc.settings.disabledMinimizedText = 'Offline - Leave a message'; embedded_svc.settings.loadingText = 'Online - Welcome to ACROBiosystems'; embedded_svc.settings.prepopulatedPrechatFields = { FirstName: onlineChatuserInfo.firstName, LastName: onlineChatuserInfo.lastName, Email: onlineChatuserInfo.email, Company_Name__c: onlineChatuserInfo.company, Question_Type__c:'', Phone: onlineChatuserInfo.phone, }; // 将联系人字段赋值给会话 embedded_svc.settings.extraPrechatFormDetails = [ {"label":"Question Type", "transcriptFields": ["Question_Type__c"]}, {"label":"Company Name", "transcriptFields": ["Contact_Company_Name__c"]}, {"label":"Phone", "transcriptFields": ["Contact_Phone__c"]}, {"label": "Source URL","value": window.location.href,"displayToAgent": true,"transcriptFields" : ["RequstURL__c"]} ]; embedded_svc.settings.widgetWidth = "320px"; embedded_svc.settings.widgetHeight = "498px"; embedded_svc.settings.directToButtonRouting = function(prechatFormData) { if (prechatFormData[4].value === "Technical") return "573A9000000002L"; if (prechatFormData[4].value === "Service") return "573A9000000002L"; if (prechatFormData[4].value === "Non-technical") return "573A9000000002Q"; } embedded_svc.settings.enabledFeatures = ['LiveAgent']; embedded_svc.settings.entryFeature = 'LiveAgent'; embedded_svc.init( 'https://d7f000005vpftua0.my.salesforce.com', 'https://d7f000005vpftua0.my.salesforce-sites.com/acrobiosystems', gslbBaseURL, '00D7F000005VpFT', 'Acrolive', { baseLiveAgentContentURL: 'https://c.la1-core1.sfdc-mchho0.salesforceliveagent.com/content', deploymentId: '572A9000000001X', buttonId: '573A9000000002Q', baseLiveAgentURL: 'https://d.la1-core1.sfdc-mchho0.salesforceliveagent.com/chat', eswLiveAgentDevName: 'EmbeddedServiceLiveAgent_Parent04IA9000000000pMAA_18792d6e3fc', isOfflineSupportEnabled: false } ); }; const onlineChatuserInfo = {firstName:'', lastName: '', email: document.getElementById("auto_user_email").value, company:document.getElementById("auto_user_company").value, phone: document.getElementById("auto_user_mobile").value}; if (!window.embedded_svc) { var s = document.createElement('script'); s.setAttribute('src', 'https://d7f000005vpftua0.my.salesforce.com/embeddedservice/5.0/esw.min.js'); s.onload = function() { initESW(null, onlineChatuserInfo); }; document.body.appendChild(s); } else { initESW('https://service.force.com', onlineChatuserInfo); } </script> <script type="text/javascript"> var loadInit = self.setInterval("loadInput()", 300); var loadInit2 = self.setInterval("loadInput2()", 300); function loadInput2() { var comdiv = document.getElementsByClassName("showDockableContainer")[0]; var sidebar = document.getElementsByClassName("sidebarBody")[0]; if (comdiv != undefined) { // 弹窗 Header var buttonElement = document.querySelector( "[c-preChatHeaderLWC_preChatHeaderLWC-host]" ); // 鼠标形状是小手 if(buttonElement != undefined){ buttonElement.style.cursor ='pointer'; } if(comdiv.style.width == "320px"){ sidebar.style.width = "318px" } var dismaxbuttonId = ''; var minbuttonId = ''; if( dismaxbuttonId == '' || minbuttonId == ''){ for(var i = 0;i < 100;i++){ var indexNo = i == 0?'1':i+'1'; 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var minbutton ; var disminbutton; var minbutton2; var closebutton; if(buttonElement != undefined){ //最大化按钮 maxbutton = buttonElement.shadowRoot.querySelector( 'lightning-icon[class="slds-icon-utility-expand-alt slds-icon_container"]' ); // 隐藏 最大化按钮 dismaxbutton = buttonElement.shadowRoot.querySelector( dismaxbuttonId ); //还原按钮 minbutton = buttonElement.shadowRoot.querySelector( 'lightning-icon[class="slds-icon-utility-contract-alt slds-icon_container"]' ); // 隐藏 还原按钮 disminbutton = buttonElement.shadowRoot.querySelector( minbuttonId ); // 最小化按钮 minbutton2 = buttonElement.shadowRoot.querySelector( 'lightning-icon[class="slds-icon-utility-minimize-window slds-icon_container"]' ); // 关闭按钮 closebutton = buttonElement.shadowRoot.querySelector( 'lightning-icon[class="slds-icon-utility-close slds-icon_container"]' ); } //最大化 if (maxbutton != undefined) { // 隐藏 最大化图标 if(comdiv.style.height != "100vh" ){ disminbutton.style.display= 'none'; dismaxbutton.style.display= 'block'; } // 保留最大化前弹窗位置 var popupLeft = comdiv.style.left; 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comdiv.style.height = "498px"; sidebar.style.width = "318px"; sidebar.style.height = "498px"; clearInterval(loadInit2); }; } else { clearInterval(loadInit2); } }; } if(minbutton2 != undefined){ minbutton2.onclick = function () { dismaxbutton.style.display= 'block'; disminbutton.style.display= 'none'; } } if(closebutton != undefined){ closebutton.onclick = function () { dismaxbutton.style.display= 'block'; disminbutton.style.display= 'none'; } } loadInput(); // 弹窗移动 if(buttonElement != undefined){ buttonElement.onmousedown = function (e) { //spaceX鼠标在登录弹窗中,距离左边框的左偏移量 var spaceX = e.clientX - comdiv.offsetLeft; //spaceY鼠标在登录弹窗中,距离上边框的上偏移量 var spaceY = e.clientY - comdiv.offsetTop; //按下login_title区域,为整个网页文档注册鼠标移动事件 document.onmousemove = function (e) { if(comdiv.style.width == "320px"){ sidebar.style.width = "318px" } var clientHeight = document.documentElement.clientHeight || document.body.clientHeight; var clientwidth = document.documentElement.clientWidth || document.body.clientWidth; var x = e.clientX - spaceX; // 移动弹窗时 左右限制 if(x <0){ x=0; } else if(x > clientwidth - comdiv.offsetWidth){ x = clientwidth - comdiv.offsetWidth; } // 移动弹窗时 上下限制 var y = e.clientY - spaceY; if(y <0){ y=0; } else if(y >clientHeight -comdiv.offsetHeight){ y = clientHeight -comdiv.offsetHeight; } comdiv.style.left = x + "px"; comdiv.style.top = y + "px"; }; e.preventDefault(); }; //松开下login_title区域,为整个网页文档解绑鼠标移动事件 buttonElement.onmouseup = function (evn) { evn.preventDefault(); buttonElement.onmousemove = null; document.onmousemove = null; }; } } if(comdiv != undefined){ // 定义4个变量 var disX = 0;//鼠标按下时光标的X值 var disY = 0;//鼠标按下时光标的Y值 var disW = 0; //拖拽前div的宽 var disH = 0; // 拖拽前div的高 //3. 给小div加点击事件 comdiv.onmouseover = function (evs) { var evs = evs || window.event; var offsetLeft = comdiv.offsetLeft; var getfoc = Math.abs(evs.clientX - (parseInt(offsetLeft)+comdiv.offsetWidth)); console.log('getfoc====>'+getfoc); if( getfoc == 1 || getfoc == 2 ){ comdiv.style.cursor ='col-resize'; document.onmousedown = function (ev) { var ev = ev || window.event; disX = ev.clientX; // 获取鼠标按下时光标x的值 disY = ev.clientY; // 获取鼠标按下时光标Y的值 if(sidebar != undefined){ disW = sidebar.offsetWidth; // 获取拖拽前div的宽 disH = sidebar.offsetHeight; // 获取拖拽前div的高 } document.onmousemove = function (evm) { var clientHeight = document.documentElement.clientHeight || document.body.clientHeight; var clientwidth = document.documentElement.clientWidth || document.body.clientWidth; console.log('clientwidth===>'+clientwidth); var evm = evm || window.event; //拖拽时为了对宽和高 限制一下范围,定义两个变量 var W = evm.clientX - disX + disW; var H = evm.clientY - disY + disH; if (W < 320) { W = 320; } else if (W > clientwidth-40 ){ W = clientwidth-40 ; } if (H < 498) { H = 498; } else if (H > clientHeight ){ H = clientHeight ; } if(sidebar != undefined){ sidebar.style.width = (W-2) + 'px';// 拖拽后物体的宽 sidebar.style.height = H + 'px';// 拖拽后物体的高 } if(comdiv != undefined){ comdiv.style.width = W + 'px';// 拖拽后物体的宽 comdiv.style.height = H + 'px';// 拖拽后物体的高 } evm.preventDefault(); } document.onmouseup = function (evn) { var evn = evn || window.event; 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} }else{ layer.msg('Submission failure!'); layer.close(loading); } } },'json') return false; }); $('#logout').click(function(){ layer.confirm('Are you sure to logout?', { btn: ['Yes','Cancel'] //按钮 }, function(){ layer.load(); $.post('/user.php?act=logout','',function(data){ window.location.reload() },'json') } ) return false; }); </script> <script type="text/javascript" src="/static/main/js/form_controller.js?v=20241125"></script> <script type="text/javascript" src="/static/main/js/history.js?v=20211009"></script> <script src="https://material.weiling.cn/h5/willing-third-party-js/v1/form-custom-ms-v1.min.js"></script> <script type="text/javascript" > // AutoComplete 自动完成 initialize(); function initialize(){ elemCSS={ focus:{'color':'#cc3536','background':'#f5f5f5'}, blur:{'color':'#333','background':'#fff'} }; inputUse=document.getElementById("inputUser"); showUse=document.getElementById("showUser"); var bodyDiv=document.getElementById("bodyDiv"); showUse.style.display="none"; inputUse.style.width=bodyDiv.style.width; 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td=document.createElement('td'); td.innerHTML = '<a href="javascript:void(null);">'+source[i]+'</a>'; tr.appendChild(td); table.appendChild(tr); showUse.appendChild(table); nn++ } } if(showUse.getElementsByTagName('a').length){ showUse.style.display=""; }else{ showUse.style.display="none"; } } function forbid(){ $(document).keydown(function(event){ if (event.keyCode == 40 || event.keyCode == 38) event.preventDefault(); }) } forbid(); function inputKeydown(event){ event = event || window.event; if(event.keyCode==40){ if(showUse.style.display==""){ showUse.getElementsByTagName('a')[0].focus(); }else{ inputUse.focus(); } } else if(event.keyCode==38){ if(showUse.style.display==""){ showUse.getElementsByTagName('a')[showUse.getElementsByTagName('a').length-1].focus(); }else{ inputUse.focus(); } } else if(event.keyCode==9){ showUse.innerHTML=''; showUse.style.display="none"; } } function inputBlur(){ clearInterval(this.timer); var current=0; var aArray=showUse.getElementsByTagName('a'); var len=aArray.length-1; var select=document.getElementById("selector"); var aClick = function(){ inputUse.value=this.childNodes[0].data; inputValue=inputUse.value; showUse.innerHTML=''; showUse.style.display='none'; inputUse.focus(); $("#search-history").click(); }; var aFocus = function(){ for(var i=len; i>=0; i--){ if(this.parentNode===select.childNodes[i].childNodes[0]){ current = i; break; } } for(var k in elemCSS.focus){ this.style[k] = elemCSS.focus[k]; } }; var aBlur= function(){ for(var k in elemCSS.blur) this.style[k] = elemCSS.blur[k]; }; var aKeydown = function(event){ event = event || window.event; if(event.keyCode===9){ showUse.innerHTML=''; showUse.style.display = 'none'; inputUse.focus(); } else if(event.keyCode==40){ current++; if(current>len){ current=-1; inputUse.focus(); }else{ select.getElementsByTagName('a')[current].focus(); } } else if(event.keyCode==38){ current--; if(current<0){ inputUse.focus(); }else{ select.getElementsByTagName('a')[current].focus(); } } }; for(var i=0; i<aArray.length; i++){ aArray[i].onclick = aClick; aArray[i].onfocus = aFocus; aArray[i].onblur = aBlur; aArray[i].onkeydown = aKeydown; } } </script> <script> function getCookie(name) { var nameEQ = name + "="; var ca = document.cookie.split(';'); for(var i=0;i < ca.length;i++) { var c = ca[i]; while (c.charAt(0)==' ') { c = c.substring(1,c.length); } if (c.indexOf(nameEQ) == 0) { return unescape(c.substring(nameEQ.length,c.length)); } } return ''; } function clearCookie(name) { setCookie(name, "", -1); } function setCookie(name, value, seconds) { seconds = seconds || 0; var expires = ""; if (seconds != 0 ) { var date = new Date(); date.setTime(date.getTime()+(seconds*1000)); expires = "; expires="+date.toGMTString(); } document.cookie = name+"="+escape(value)+expires+"; path=/"; } </script> <script type="text/javascript" src="/static/main/js/referrer_source.js"></script> <script> setCookie('user_from_region', '亚太区'); setCookie('user_from_country', 'Singapore'); </script> <script> $(function () { //存储进入网站的上一页链接 if(document.cookie.indexOf("zfx_referrer=") == -1){ setCookie("zfx_referrer",decodeURI(document.referrer),1800); } //存储进入网站的上一页链接 END //google $(".newLoginSubmit").click(function () { var email = $(this).parents('form').find("#email").val(); var label = email == "" ? 'login' : email; gtag('event', 'click', { 'event_category': 'userLogin', 'event_label': label }); }) $(".newRegSubmit").click(function () { var email = $(this).parents('form').find("#email").val(); var label = email == "" ? 'register' : email; gtag('event', 'click', { 'event_category': 'userRegister', 'event_label': label }); }) //导航条点击 $(".nav a").click(function () { var label = $(this).html(); gtag('event', 'click', { 'event_category': 'webNav', 'event_label': label }); }) //底部图标点击 $(".google_icon a").click(function () { var label = $(this).attr('href'); gtag('event', 'click', { 'event_category': 'commonFooterIcon', 'event_label': label }); }) //google }) </script> <script src="//cbe.huiju.cool/cbe/collect?tid=105249838&at=0&h=web"></script> <script> huiju_tag = typeof(huiju_tag) == 'undefined' || huiju_tag == "" ? 'other' : huiju_tag; var url = window.location.pathname; var url_arr = url.match(/\/([A|L][0-9]{1,10})-/); huiju_tag = url_arr != null ? url_arr[1] : huiju_tag; try{ clab_tracker.ready(function(){ const s = { source: getCookie("zfx_utm_source"), source1: getCookie('zfx_utm_medium'), source8: getCookie('zfx_utm_term'), contentName: getCookie('zfx_utm_content'), source7: getCookie('zfx_utm_campaign') }; this.push(s); if(Request.cid) this.push({customerId: Request.cid}); this.push({"pageType":"web"}); this.track("open_page", { tag: huiju_tag, identityType: 'email', identityValue: $("#auto_user_email").val() }); }); } catch (e) { var clab_tracker = {push: function() {}, track: function() {}} } function getFormatDate(){ var nowDate = new Date(); var year = nowDate.getFullYear(); var month = nowDate.getMonth() + 1 < 10 ? "0" + (nowDate.getMonth() + 1) : nowDate.getMonth() + 1; var date = nowDate.getDate() < 10 ? "0" + nowDate.getDate() : nowDate.getDate(); var hour = nowDate.getHours()< 10 ? "0" + nowDate.getHours() : nowDate.getHours(); var minute = nowDate.getMinutes()< 10 ? "0" + nowDate.getMinutes() : nowDate.getMinutes(); var second = nowDate.getSeconds()< 10 ? "0" + nowDate.getSeconds() : nowDate.getSeconds(); return year + "-" + month + "-" + date+" "+hour+":"+minute+":"+second; } </script> <script type="text/javascript" src="//s7.addthis.com/js/300/addthis_widget.js#pubid=ra-5e4c92a56435a9d4"></script> </body> </html>

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