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IAJPS publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation.Topics covered are: Pharmaceutics, Bio Pharmaceutics and Pharmacokinetics, Novel Drug Delivery System, Pharmaceutical chemistry including medicinal and analytical chemistry<br /><b>Address: </b>Hyderabad, Andhra Pradesh, India<br /><div class="js-profile-less-about u-linkUnstyled u-tcGrayDarker u-textDecorationUnderline u-displayNone">less</div></div></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span><a class="ri-more-link js-profile-ri-list-card" data-click-track="profile-user-info-primary-research-interest" data-has-card-for-ri-list="15402473">View All (7)</a></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="15402473" href="https://www.academia.edu/Documents/in/Pharmacy"><div 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class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96868605/Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC">Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://cvr.academia.edu/RaviPulla">Ravi Pulla</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://nagajunauniversity.academia.edu/Editoriajps">Editor iajps</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron Hydrochloride (AST) in tablet dosage forms. Waters Spherisorb ® 5μm CN, 250x4.6 mm, column with 5 μm particle size and the Mobile Phase consisting of 0.01M Ammonium Acetate in water adjusting the pH-3.2 with Methanol & Tetra Hydro Furan in ratio of 700:240:60 v/v & mobile phase used as a diluent in the gradient mode. The flow rate was 1.0 ml/min and the effluents were monitored at 295 nm. The retention time was 11.570 min and the detector response was linear in the concentration range of 56.1673.2 μg/mL for AST successively. The respective linear regression equation being Y= 27228.755x + 221036.4041 for AST. The Limit of Detection (LOD) & The Limit of Quantification (LOQ) was found to be 0.1 & 0.3 μg/mL for AST. The percentage assay of AST was 99.93%. The method was validated by determining its accuracy, precision and system suitability. The results of the study showed that the proposed...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96868605"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96868605"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96868605; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96868605]").text(description); $(".js-view-count[data-work-id=96868605]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96868605; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96868605']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96868605, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=96868605]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96868605,"title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC","translated_title":"","metadata":{"abstract":"A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron Hydrochloride (AST) in tablet dosage forms. Waters Spherisorb ® 5μm CN, 250x4.6 mm, column with 5 μm particle size and the Mobile Phase consisting of 0.01M Ammonium Acetate in water adjusting the pH-3.2 with Methanol \u0026 Tetra Hydro Furan in ratio of 700:240:60 v/v \u0026 mobile phase used as a diluent in the gradient mode. The flow rate was 1.0 ml/min and the effluents were monitored at 295 nm. The retention time was 11.570 min and the detector response was linear in the concentration range of 56.1673.2 μg/mL for AST successively. The respective linear regression equation being Y= 27228.755x + 221036.4041 for AST. The Limit of Detection (LOD) \u0026 The Limit of Quantification (LOQ) was found to be 0.1 \u0026 0.3 μg/mL for AST. The percentage assay of AST was 99.93%. The method was validated by determining its accuracy, precision and system suitability. The results of the study showed that the proposed...","publication_date":{"day":null,"month":null,"year":2014,"errors":{}}},"translated_abstract":"A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron Hydrochloride (AST) in tablet dosage forms. Waters Spherisorb ® 5μm CN, 250x4.6 mm, column with 5 μm particle size and the Mobile Phase consisting of 0.01M Ammonium Acetate in water adjusting the pH-3.2 with Methanol \u0026 Tetra Hydro Furan in ratio of 700:240:60 v/v \u0026 mobile phase used as a diluent in the gradient mode. The flow rate was 1.0 ml/min and the effluents were monitored at 295 nm. The retention time was 11.570 min and the detector response was linear in the concentration range of 56.1673.2 μg/mL for AST successively. The respective linear regression equation being Y= 27228.755x + 221036.4041 for AST. The Limit of Detection (LOD) \u0026 The Limit of Quantification (LOQ) was found to be 0.1 \u0026 0.3 μg/mL for AST. The percentage assay of AST was 99.93%. The method was validated by determining its accuracy, precision and system suitability. The results of the study showed that the proposed...","internal_url":"https://www.academia.edu/96868605/Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC","translated_internal_url":"","created_at":"2023-02-13T23:08:56.338-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":48709433,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":40970087,"work_id":96868605,"tagging_user_id":48709433,"tagged_user_id":289144415,"co_author_invite_id":null,"email":"a***n@gmail.com","display_order":0,"name":"asadulla khan","title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC"},{"id":40970088,"work_id":96868605,"tagging_user_id":48709433,"tagged_user_id":33192926,"co_author_invite_id":null,"email":"s***4@gmail.com","display_order":1073741824,"name":"Sorabh Agrawal","title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC"},{"id":40970089,"work_id":96868605,"tagging_user_id":48709433,"tagged_user_id":15402473,"co_author_invite_id":null,"email":"i***r@gmail.com","affiliation":"ANU-NARGANAJUNA","display_order":1610612736,"name":"Editor iajps","title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC"}],"downloadable_attachments":[],"slug":"Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":48709433,"first_name":"Ravi","middle_initials":null,"last_name":"Pulla","page_name":"RaviPulla","domain_name":"cvr","created_at":"2016-05-14T06:13:18.288-07:00","display_name":"Ravi Pulla","url":"https://cvr.academia.edu/RaviPulla","email":"eEE3UXZjQ25OQ040Q0xIV0krMHZROTVkd3FBdzZCcGdUdUptVDJ5dGtPb0NSaFhWT1JSVzVtb2VPRmtxd3IyNy0taFVuVk9JdldlcnZOa1J3eGpPL0srZz09--d7e3fca9c2997c6436929093b60f33019927beea"},"attachments":[],"research_interests":[{"id":36149,"name":"Pharmaceutical Analysis","url":"https://www.academia.edu/Documents/in/Pharmaceutical_Analysis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="106479377"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/106479377/A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review"><img alt="Research paper thumbnail of A Study Of The Factors Affecting The Growing Presence Of Girls In Iranian Universities For Continuing Their Higher Education: A Review" class="work-thumbnail" src="https://attachments.academia-assets.com/105665679/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/106479377/A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review">A Study Of The Factors Affecting The Growing Presence Of Girls In Iranian Universities For Continuing Their Higher Education: A Review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: Since during the few past decades we have been witness to the unprecedented increas...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: Since during the few past decades we have been witness to the unprecedented increase in the presence of girls in Iranian universities for continuing their higher education, the current study seeks to study this issue through literature review. Materials and Methods: This study has been conducted in the form of a simple literature review. Research data are collected via searching the published papers in trusted Iranian and Foreign websites based on the following key words &quot;girls, continuing education, university and Iran&quot;. Findings: Generally speaking, the factors affecting the increase of the presence of girls in Iranian universities for continuing their education can be sought for in the following elements: economic motives (getting a job, acquiring financial independence, skill and economic vision acquisition), political motives (further participation in political affairs, having the ability to comment upon political affairs, acquiring vital and sensitive p...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b4a939da69b1ae64b5b1e031dd79038f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105665679,"asset_id":106479377,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105665679/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="106479377"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="106479377"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 106479377; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=106479377]").text(description); $(".js-view-count[data-work-id=106479377]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 106479377; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='106479377']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 106479377, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b4a939da69b1ae64b5b1e031dd79038f" } } $('.js-work-strip[data-work-id=106479377]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":106479377,"title":"A Study Of The Factors Affecting The Growing Presence Of Girls In Iranian Universities For Continuing Their Higher Education: A Review","translated_title":"","metadata":{"abstract":"Introduction: Since during the few past decades we have been witness to the unprecedented increase in the presence of girls in Iranian universities for continuing their higher education, the current study seeks to study this issue through literature review. Materials and Methods: This study has been conducted in the form of a simple literature review. Research data are collected via searching the published papers in trusted Iranian and Foreign websites based on the following key words \u0026quot;girls, continuing education, university and Iran\u0026quot;. Findings: Generally speaking, the factors affecting the increase of the presence of girls in Iranian universities for continuing their education can be sought for in the following elements: economic motives (getting a job, acquiring financial independence, skill and economic vision acquisition), political motives (further participation in political affairs, having the ability to comment upon political affairs, acquiring vital and sensitive p...","publisher":"Zenodo","publication_date":{"day":4,"month":2,"year":2018,"errors":{}}},"translated_abstract":"Introduction: Since during the few past decades we have been witness to the unprecedented increase in the presence of girls in Iranian universities for continuing their higher education, the current study seeks to study this issue through literature review. Materials and Methods: This study has been conducted in the form of a simple literature review. Research data are collected via searching the published papers in trusted Iranian and Foreign websites based on the following key words \u0026quot;girls, continuing education, university and Iran\u0026quot;. Findings: Generally speaking, the factors affecting the increase of the presence of girls in Iranian universities for continuing their education can be sought for in the following elements: economic motives (getting a job, acquiring financial independence, skill and economic vision acquisition), political motives (further participation in political affairs, having the ability to comment upon political affairs, acquiring vital and sensitive p...","internal_url":"https://www.academia.edu/106479377/A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review","translated_internal_url":"","created_at":"2023-09-11T07:14:28.164-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105665679,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665679/thumbnails/1.jpg","file_name":"84.Gilavand_2011_201.pdf","download_url":"https://www.academia.edu/attachments/105665679/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_The_Factors_Affecting_The_Gro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665679/84.Gilavand_2011_201-libre.pdf?1694442726=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_The_Factors_Affecting_The_Gro.pdf\u0026Expires=1732719331\u0026Signature=cu27lsJPNN9tULhS7GILY19gf6ZaAROHFXVSeGSyNiOLpMlHSC1vWZF7E0wb1gVqewt3cmPB~egwp9Vl6WoD9NglOsGzmm82ogdK2E1eXyF9WkPWV~urKgB9VXVCQG02JLVw9vjCtC9dDjJxwQhtMg1bgLCmdJMFFNCZOyaDz6nFIcmGKf7k9USlS2SkFiAcPiCJkxVlFEAJByvYbyfkKjbnYbGPpnrazc9gz-OTpC-srC6FwkyW7sbXAFfxb5qdP7MzYWebzlxHWlGhMW-rkReUvEQEZ96KIhHMKrjXnWIWYKea~GSljPrtND9rxljPHsBYo22xnGJZikZ-6Y2uoQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":105665679,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665679/thumbnails/1.jpg","file_name":"84.Gilavand_2011_201.pdf","download_url":"https://www.academia.edu/attachments/105665679/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_The_Factors_Affecting_The_Gro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665679/84.Gilavand_2011_201-libre.pdf?1694442726=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_The_Factors_Affecting_The_Gro.pdf\u0026Expires=1732719331\u0026Signature=cu27lsJPNN9tULhS7GILY19gf6ZaAROHFXVSeGSyNiOLpMlHSC1vWZF7E0wb1gVqewt3cmPB~egwp9Vl6WoD9NglOsGzmm82ogdK2E1eXyF9WkPWV~urKgB9VXVCQG02JLVw9vjCtC9dDjJxwQhtMg1bgLCmdJMFFNCZOyaDz6nFIcmGKf7k9USlS2SkFiAcPiCJkxVlFEAJByvYbyfkKjbnYbGPpnrazc9gz-OTpC-srC6FwkyW7sbXAFfxb5qdP7MzYWebzlxHWlGhMW-rkReUvEQEZ96KIhHMKrjXnWIWYKea~GSljPrtND9rxljPHsBYo22xnGJZikZ-6Y2uoQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2621,"name":"Higher Education","url":"https://www.academia.edu/Documents/in/Higher_Education"}],"urls":[{"id":33883885,"url":"https://zenodo.org/record/1165235/files/84.Gilavand%2011%20(1).pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="106479371"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/106479371/A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information"><img alt="Research paper thumbnail of A Study Of Ahvaz Jundishapur University Of Medical Sciences Dental Students' Interest To Pursuing A Specialty According To Their Demographic Information" class="work-thumbnail" src="https://attachments.academia-assets.com/105665700/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/106479371/A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information">A Study Of Ahvaz Jundishapur University Of Medical Sciences Dental Students' Interest To Pursuing A Specialty According To Their Demographic Information</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Today, the changes in the expectations of the society from the dentists and the need for higher q...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Today, the changes in the expectations of the society from the dentists and the need for higher quality dental services have renewed the interests of people to pursue their education in the field of dental sciences. This study has tried to examine the degree of the students&#39; interest at Jundishapur University of Medical Sciences (AJUMS) to Pursuing a Specialty in the field of dental sciences according to their demographic data. This study is descriptive-analytical and has used a cross-sectional method of analysis during March 2015. The research population includes 484 of Professional Doctorate| (General) of dentistry students in the field of dental sciences at the university. Sampling was done by survey and questionnaire. Among all the students, 118 from the Faculty of Dental Sciences (tuition-free) and 58 from the Campus Unit (tuition-based) completed the questionnaire. To analyze the data descriptive statistics, frequency, frequency percentage, Kolmogorov–Smirnov test, and non...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4b8c95b08c6609f2cd755889e15fac68" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105665700,"asset_id":106479371,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105665700/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="106479371"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="106479371"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 106479371; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=106479371]").text(description); $(".js-view-count[data-work-id=106479371]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 106479371; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='106479371']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 106479371, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4b8c95b08c6609f2cd755889e15fac68" } } $('.js-work-strip[data-work-id=106479371]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":106479371,"title":"A Study Of Ahvaz Jundishapur University Of Medical Sciences Dental Students' Interest To Pursuing A Specialty According To Their Demographic Information","translated_title":"","metadata":{"abstract":"Today, the changes in the expectations of the society from the dentists and the need for higher quality dental services have renewed the interests of people to pursue their education in the field of dental sciences. 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To analyze the data descriptive statistics, frequency, frequency percentage, Kolmogorov–Smirnov test, and non...","publisher":"Zenodo","publication_date":{"day":27,"month":6,"year":2017,"errors":{}}},"translated_abstract":"Today, the changes in the expectations of the society from the dentists and the need for higher quality dental services have renewed the interests of people to pursue their education in the field of dental sciences. This study has tried to examine the degree of the students\u0026#39; interest at Jundishapur University of Medical Sciences (AJUMS) to Pursuing a Specialty in the field of dental sciences according to their demographic data. This study is descriptive-analytical and has used a cross-sectional method of analysis during March 2015. The research population includes 484 of Professional Doctorate| (General) of dentistry students in the field of dental sciences at the university. Sampling was done by survey and questionnaire. Among all the students, 118 from the Faculty of Dental Sciences (tuition-free) and 58 from the Campus Unit (tuition-based) completed the questionnaire. To analyze the data descriptive statistics, frequency, frequency percentage, Kolmogorov–Smirnov test, and non...","internal_url":"https://www.academia.edu/106479371/A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information","translated_internal_url":"","created_at":"2023-09-11T07:14:10.882-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105665700,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665700/thumbnails/1.jpg","file_name":"26.IAJPS26062017.pdf","download_url":"https://www.academia.edu/attachments/105665700/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_Ahvaz_Jundishapur_University.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665700/26.IAJPS26062017-libre.pdf?1694442724=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_Ahvaz_Jundishapur_University.pdf\u0026Expires=1732784475\u0026Signature=hA9zXLBj90ubvsKJ8qfFYp9jUCgBIZNVApwfceSqI-X4Kv3cmFQk4gHEkwkd1vupo-9k9IwvgUxVUO8GF1ze0F8UKindpm1uSWbtqIEPF2L9BoN00nEoEYP6SjKQAig~OzFQwMkguWK0WC6iAFDZCAEcWIUpPwiwZO1vnNVhfh6gf8mF50bfb3JNsJ42H8iDCX4Yew2gpjcHaNlAYtzEASPUh4s~QeK6fHyUTHg871SQJJKj0L4l41nUpCEP~~CyjPiAX-mifFVJe0G1EwOlgDvClbsf~ECp8N1V4mxEF9f8fPo44SL0c7o37jY3sO8~oq5S42ZdKK5QImHwPfflyw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":105665700,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665700/thumbnails/1.jpg","file_name":"26.IAJPS26062017.pdf","download_url":"https://www.academia.edu/attachments/105665700/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_Ahvaz_Jundishapur_University.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665700/26.IAJPS26062017-libre.pdf?1694442724=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_Ahvaz_Jundishapur_University.pdf\u0026Expires=1732784475\u0026Signature=hA9zXLBj90ubvsKJ8qfFYp9jUCgBIZNVApwfceSqI-X4Kv3cmFQk4gHEkwkd1vupo-9k9IwvgUxVUO8GF1ze0F8UKindpm1uSWbtqIEPF2L9BoN00nEoEYP6SjKQAig~OzFQwMkguWK0WC6iAFDZCAEcWIUpPwiwZO1vnNVhfh6gf8mF50bfb3JNsJ42H8iDCX4Yew2gpjcHaNlAYtzEASPUh4s~QeK6fHyUTHg871SQJJKj0L4l41nUpCEP~~CyjPiAX-mifFVJe0G1EwOlgDvClbsf~ECp8N1V4mxEF9f8fPo44SL0c7o37jY3sO8~oq5S42ZdKK5QImHwPfflyw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":595,"name":"Medical Sciences","url":"https://www.academia.edu/Documents/in/Medical_Sciences"},{"id":4455,"name":"Medical Education","url":"https://www.academia.edu/Documents/in/Medical_Education"},{"id":85362,"name":"Descriptive Statistics","url":"https://www.academia.edu/Documents/in/Descriptive_Statistics"},{"id":2587767,"name":"Specialty","url":"https://www.academia.edu/Documents/in/Specialty"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85675791"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85675791/FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN" class="work-thumbnail" src="https://attachments.academia-assets.com/90301611/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85675791/FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN">FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. The clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter-and intra-subject variation in bioavailability from different commercial products. Moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. In the proposed research work, we are wanting to get ready transdermal patches of an antifungal drug Griseofulvin with the accompanying goal. Transdermal patches stacked with Griseofulvin will be arranged involving polymers in changing focus by dissolvable vanishing strategy.The prearranged transdermal patches will be assessed for different boundaries like weight variety, thickness, collapsing perseverance, drug content, level of dampness content, in-vitro drug release study</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2c821d1bc138ea0b0d47e89461bf0889" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90301611,"asset_id":85675791,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90301611/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85675791"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85675791"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85675791; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85675791]").text(description); $(".js-view-count[data-work-id=85675791]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85675791; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85675791']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85675791, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2c821d1bc138ea0b0d47e89461bf0889" } } $('.js-work-strip[data-work-id=85675791]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85675791,"title":"FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN","translated_title":"","metadata":{"doi":"10.5281/zenodo.7026047","abstract":"Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. The clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter-and intra-subject variation in bioavailability from different commercial products. Moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. In the proposed research work, we are wanting to get ready transdermal patches of an antifungal drug Griseofulvin with the accompanying goal. Transdermal patches stacked with Griseofulvin will be arranged involving polymers in changing focus by dissolvable vanishing strategy.The prearranged transdermal patches will be assessed for different boundaries like weight variety, thickness, collapsing perseverance, drug content, level of dampness content, in-vitro drug release study"},"translated_abstract":"Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. The clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter-and intra-subject variation in bioavailability from different commercial products. Moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. In the proposed research work, we are wanting to get ready transdermal patches of an antifungal drug Griseofulvin with the accompanying goal. Transdermal patches stacked with Griseofulvin will be arranged involving polymers in changing focus by dissolvable vanishing strategy.The prearranged transdermal patches will be assessed for different boundaries like weight variety, thickness, collapsing perseverance, drug content, level of dampness content, in-vitro drug release study","internal_url":"https://www.academia.edu/85675791/FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN","translated_internal_url":"","created_at":"2022-08-26T10:30:41.969-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":38726710,"work_id":85675791,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":1651572,"email":"d***i@gmail.com","display_order":1,"name":"Singh Dangi","title":"FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN"},{"id":38726711,"work_id":85675791,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":6574262,"email":"p***5@gmail.com","display_order":2,"name":"Satkar Prasad","title":"FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN"}],"downloadable_attachments":[{"id":90301611,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301611/thumbnails/1.jpg","file_name":"31.IAJPS31082022.pdf","download_url":"https://www.academia.edu/attachments/90301611/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301611/31.IAJPS31082022-libre.pdf?1661536965=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf\u0026Expires=1732719332\u0026Signature=UCvrvf5pqb72DuxtyHElupqmSjZMtZaaGC9Ag-QL~XZaUVHMRycZ29aeO-RjMknLfOMTBrLC15YaDPmLstS5HXpj7OY-jhOfrkC2YfRUq~NuRFYG3-SDng5kyi7DQ7TawklyleGmKQem-fQ1Hd-pERrWgFYeaskR4JjND6HIj7twgtKdRoaFptWEvqKcgfXW5uhR-eChQ3Cb7dKS48JBQeiHcLcWlnnJFUg3~t-SCkUEI7mx9YII5ZV37XQKnzx0l2Xz79JnkBfbevLgYgF4pEMVzekeb~mfbfgTDRSxSBsgPDh3X7hr1~wMjaN-~dIfU3TCQz4niNQ-opFMZemw2g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90301611,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301611/thumbnails/1.jpg","file_name":"31.IAJPS31082022.pdf","download_url":"https://www.academia.edu/attachments/90301611/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301611/31.IAJPS31082022-libre.pdf?1661536965=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf\u0026Expires=1732719332\u0026Signature=UCvrvf5pqb72DuxtyHElupqmSjZMtZaaGC9Ag-QL~XZaUVHMRycZ29aeO-RjMknLfOMTBrLC15YaDPmLstS5HXpj7OY-jhOfrkC2YfRUq~NuRFYG3-SDng5kyi7DQ7TawklyleGmKQem-fQ1Hd-pERrWgFYeaskR4JjND6HIj7twgtKdRoaFptWEvqKcgfXW5uhR-eChQ3Cb7dKS48JBQeiHcLcWlnnJFUg3~t-SCkUEI7mx9YII5ZV37XQKnzx0l2Xz79JnkBfbevLgYgF4pEMVzekeb~mfbfgTDRSxSBsgPDh3X7hr1~wMjaN-~dIfU3TCQz4niNQ-opFMZemw2g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85675638"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85675638/EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES"><img alt="Research paper thumbnail of EVALUATION OF INVITRO ANTI-OXIDANT, TOTAL FLAVONOID CONTENT AND ANTI-MICROBIAL ACTIVITY OF SOLANUM SURATTENSE (WILD EGG PLANT) BURN LEAVES" class="work-thumbnail" src="https://attachments.academia-assets.com/90301401/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85675638/EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES">EVALUATION OF INVITRO ANTI-OXIDANT, TOTAL FLAVONOID CONTENT AND ANTI-MICROBIAL ACTIVITY OF SOLANUM SURATTENSE (WILD EGG PLANT) BURN LEAVES</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present research work relates to the preparation of ethanoic extraction of solanum surattense...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present research work relates to the preparation of ethanoic extraction of solanum surattense leaves and evaluation of extract for  the anti-oxidant and anti-microbial activity The phytochemical analysis of ethanolic extract solanum surattense has revealed the presence of various phytochemical constituents such as Alkaloids, Flavonoids, Saponins, sterols, carbohydrates, glycosides. The Antioxidant activity was analysed using hydrogen peroxide assay method  for the ethanolic  extracts of solanum  in concentrations of 10 - 50µg/Ml. The results revelaed that the ethanolic extract of solanum had showed the 60%  activity The prepared extract was evaluated for Antimicrobial  activity by using Agar well diffusion by Zone Inhibition method The antimicrobial of ethanolic exract of Solanum surattense leaves against two bacterial species at various concentrations were (20, 40,60,80,and 100µg/mL concentrations were evaluated. The results revealed that the Solanum surattense leaves showed good and better results for Antioxidant and Anti microbial activity. Thus it serves as an encouragement towards development of new drugs for the benefit of mankind.<br />Key words: solanum surattense, Leaves, Ethanolic extract, Anti-oxidant, Anti- microbial activity.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bcaf028e01904c487af3b1d20953dfef" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90301401,"asset_id":85675638,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90301401/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85675638"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85675638"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85675638; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85675638]").text(description); $(".js-view-count[data-work-id=85675638]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85675638; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85675638']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85675638, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bcaf028e01904c487af3b1d20953dfef" } } $('.js-work-strip[data-work-id=85675638]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85675638,"title":"EVALUATION OF INVITRO ANTI-OXIDANT, TOTAL FLAVONOID CONTENT AND ANTI-MICROBIAL ACTIVITY OF SOLANUM SURATTENSE (WILD EGG PLANT) BURN LEAVES","translated_title":"","metadata":{"doi":"10.5281/zenodo.7026040","abstract":"The present research work relates to the preparation of ethanoic extraction of solanum surattense leaves and evaluation of extract for the anti-oxidant and anti-microbial activity The phytochemical analysis of ethanolic extract solanum surattense has revealed the presence of various phytochemical constituents such as Alkaloids, Flavonoids, Saponins, sterols, carbohydrates, glycosides. The Antioxidant activity was analysed using hydrogen peroxide assay method for the ethanolic extracts of solanum in concentrations of 10 - 50µg/Ml. The results revelaed that the ethanolic extract of solanum had showed the 60% activity The prepared extract was evaluated for Antimicrobial activity by using Agar well diffusion by Zone Inhibition method The antimicrobial of ethanolic exract of Solanum surattense leaves against two bacterial species at various concentrations were (20, 40,60,80,and 100µg/mL concentrations were evaluated. The results revealed that the Solanum surattense leaves showed good and better results for Antioxidant and Anti microbial activity. Thus it serves as an encouragement towards development of new drugs for the benefit of mankind.\nKey words: solanum surattense, Leaves, Ethanolic extract, Anti-oxidant, Anti- microbial activity.\n"},"translated_abstract":"The present research work relates to the preparation of ethanoic extraction of solanum surattense leaves and evaluation of extract for the anti-oxidant and anti-microbial activity The phytochemical analysis of ethanolic extract solanum surattense has revealed the presence of various phytochemical constituents such as Alkaloids, Flavonoids, Saponins, sterols, carbohydrates, glycosides. The Antioxidant activity was analysed using hydrogen peroxide assay method for the ethanolic extracts of solanum in concentrations of 10 - 50µg/Ml. The results revelaed that the ethanolic extract of solanum had showed the 60% activity The prepared extract was evaluated for Antimicrobial activity by using Agar well diffusion by Zone Inhibition method The antimicrobial of ethanolic exract of Solanum surattense leaves against two bacterial species at various concentrations were (20, 40,60,80,and 100µg/mL concentrations were evaluated. The results revealed that the Solanum surattense leaves showed good and better results for Antioxidant and Anti microbial activity. Thus it serves as an encouragement towards development of new drugs for the benefit of mankind.\nKey words: solanum surattense, Leaves, Ethanolic extract, Anti-oxidant, Anti- microbial activity.\n","internal_url":"https://www.academia.edu/85675638/EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES","translated_internal_url":"","created_at":"2022-08-26T10:27:21.047-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90301401,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301401/thumbnails/1.jpg","file_name":"30.IAJPS30082022.pdf","download_url":"https://www.academia.edu/attachments/90301401/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301401/30.IAJPS30082022-libre.pdf?1661535903=\u0026response-content-disposition=attachment%3B+filename%3DEVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf\u0026Expires=1732784475\u0026Signature=UCrRpUkdR8WJ9s4TkFWCcQPs5eD99PNkbdQH4wE7EM834w5iBnQonmQRQAXBmpTeJ1anUsrzNRY1WxIUGaPSt422AKqgpmvWMIHky1UkH-5NWgo4COb21Uaz~QKhO3XxV97gWIkpF2GbeXpjSwFBpINPoeMxwxjC6S6aCwztOz2uFmy0yrCI614~3UCcOezrWj0ywwMkpaRkoSKiLdgjLmtktJJfOaN5AbzE~e2I11wuNVEdp7YxQETcWIkyILERu4TNCFgsVfw2t6iEZzjC9f5i9~QOYU~JYy03C5oH4JrYCxPJowX24RXE61LV6CxXO4MzAPBFg4TEel0MgZ1J7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90301401,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301401/thumbnails/1.jpg","file_name":"30.IAJPS30082022.pdf","download_url":"https://www.academia.edu/attachments/90301401/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301401/30.IAJPS30082022-libre.pdf?1661535903=\u0026response-content-disposition=attachment%3B+filename%3DEVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf\u0026Expires=1732784475\u0026Signature=UCrRpUkdR8WJ9s4TkFWCcQPs5eD99PNkbdQH4wE7EM834w5iBnQonmQRQAXBmpTeJ1anUsrzNRY1WxIUGaPSt422AKqgpmvWMIHky1UkH-5NWgo4COb21Uaz~QKhO3XxV97gWIkpF2GbeXpjSwFBpINPoeMxwxjC6S6aCwztOz2uFmy0yrCI614~3UCcOezrWj0ywwMkpaRkoSKiLdgjLmtktJJfOaN5AbzE~e2I11wuNVEdp7YxQETcWIkyILERu4TNCFgsVfw2t6iEZzjC9f5i9~QOYU~JYy03C5oH4JrYCxPJowX24RXE61LV6CxXO4MzAPBFg4TEel0MgZ1J7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85586533"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85586533/STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES"><img alt="Research paper thumbnail of STANDARDIZATION AND MICROSCOPICAL EVALUATION STUDIES OF CENTELLA ASIATICA LINN. (BRAHMI) LEAVES" class="work-thumbnail" src="https://attachments.academia-assets.com/90238522/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85586533/STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES">STANDARDIZATION AND MICROSCOPICAL EVALUATION STUDIES OF CENTELLA ASIATICA LINN. (BRAHMI) LEAVES</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Based on trial-and-error experience and folk remedies continue to draw wide attention for their r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Based on trial-and-error experience and folk remedies continue to draw wide attention for their role in the treatment of mild and chronic diseases. We focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional systems of medicine. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in India. Triterpenoids, Saponins, the primary constituents of Centella asiatica are mainly believed to be responsible for its wide therapeutic actions. The herb is recommended for the treatment of various diseases like leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhea, fever, amenorrhea and Alzheimer's. The present work employs the standardization and microscopical evaluation of leaf drug to authenticate by methodological parameters ranges of Stomatal number, Vein islet number and Stomatal index of the crud drug. Respective practical and morphological parameters of the drug of Centella asiatica. Various microsopical parameters to evaluate the characteristics are reported, which is imperative for the safe utilization of the herb, are discussed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="652e51428cdca04e6e7c75947a084140" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90238522,"asset_id":85586533,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90238522/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85586533"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85586533"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85586533; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85586533]").text(description); $(".js-view-count[data-work-id=85586533]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85586533; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85586533']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85586533, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "652e51428cdca04e6e7c75947a084140" } } $('.js-work-strip[data-work-id=85586533]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85586533,"title":"STANDARDIZATION AND MICROSCOPICAL EVALUATION STUDIES OF CENTELLA ASIATICA LINN. (BRAHMI) LEAVES","translated_title":"","metadata":{"doi":"10.5281/zenodo.7022696","abstract":"Based on trial-and-error experience and folk remedies continue to draw wide attention for their role in the treatment of mild and chronic diseases. We focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional systems of medicine. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in India. Triterpenoids, Saponins, the primary constituents of Centella asiatica are mainly believed to be responsible for its wide therapeutic actions. The herb is recommended for the treatment of various diseases like leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhea, fever, amenorrhea and Alzheimer's. The present work employs the standardization and microscopical evaluation of leaf drug to authenticate by methodological parameters ranges of Stomatal number, Vein islet number and Stomatal index of the crud drug. Respective practical and morphological parameters of the drug of Centella asiatica. Various microsopical parameters to evaluate the characteristics are reported, which is imperative for the safe utilization of the herb, are discussed."},"translated_abstract":"Based on trial-and-error experience and folk remedies continue to draw wide attention for their role in the treatment of mild and chronic diseases. We focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional systems of medicine. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in India. Triterpenoids, Saponins, the primary constituents of Centella asiatica are mainly believed to be responsible for its wide therapeutic actions. The herb is recommended for the treatment of various diseases like leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhea, fever, amenorrhea and Alzheimer's. The present work employs the standardization and microscopical evaluation of leaf drug to authenticate by methodological parameters ranges of Stomatal number, Vein islet number and Stomatal index of the crud drug. Respective practical and morphological parameters of the drug of Centella asiatica. Various microsopical parameters to evaluate the characteristics are reported, which is imperative for the safe utilization of the herb, are discussed.","internal_url":"https://www.academia.edu/85586533/STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES","translated_internal_url":"","created_at":"2022-08-25T03:47:59.000-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90238522,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238522/thumbnails/1.jpg","file_name":"25.IAJPS25082022.pdf","download_url":"https://www.academia.edu/attachments/90238522/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"STANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238522/25.IAJPS25082022-libre.pdf?1661437749=\u0026response-content-disposition=attachment%3B+filename%3DSTANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf\u0026Expires=1732784475\u0026Signature=cQvzFDTl37~sdWaw8KkSKMvpAPVms98KW315YzpHzV0Z7uvYe9UYZB8F8l~2GQNFGP5WonWxAm8b29ZliZKhbkGOn1pvt9BY9ioeJRmtQfwZ7cSrwx8cs5HtTkao7Yfk9OyRD7vh7jdaJieXShs~kbRfAlqKYUacE2YAR5NwBCDt6FPWBzkLudTxnR9YbYD2bvwqk~Kr-aWTDHllstV-7x-wsGl0Tma21uXPjTXr8Rf1r-u0KfeGKAFAe4LXJ4OjiVUTB94fxCSgZDBRJ92x82QZvCAxd~k9z7ngLOTU8kGs5VAR~f85GEAbj~oqoCL4vqgys-WKIMNIVxYz5AHB5A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90238522,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238522/thumbnails/1.jpg","file_name":"25.IAJPS25082022.pdf","download_url":"https://www.academia.edu/attachments/90238522/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"STANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238522/25.IAJPS25082022-libre.pdf?1661437749=\u0026response-content-disposition=attachment%3B+filename%3DSTANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf\u0026Expires=1732784475\u0026Signature=cQvzFDTl37~sdWaw8KkSKMvpAPVms98KW315YzpHzV0Z7uvYe9UYZB8F8l~2GQNFGP5WonWxAm8b29ZliZKhbkGOn1pvt9BY9ioeJRmtQfwZ7cSrwx8cs5HtTkao7Yfk9OyRD7vh7jdaJieXShs~kbRfAlqKYUacE2YAR5NwBCDt6FPWBzkLudTxnR9YbYD2bvwqk~Kr-aWTDHllstV-7x-wsGl0Tma21uXPjTXr8Rf1r-u0KfeGKAFAe4LXJ4OjiVUTB94fxCSgZDBRJ92x82QZvCAxd~k9z7ngLOTU8kGs5VAR~f85GEAbj~oqoCL4vqgys-WKIMNIVxYz5AHB5A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85586353"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85586353/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TERBUTALIINE SULFATE" class="work-thumbnail" src="https://attachments.academia-assets.com/90238323/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85586353/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE">FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TERBUTALIINE SULFATE</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The outcome of present work provides a concrete basis for development of fast dissolving tablets ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The outcome of present work provides a concrete basis for development of fast dissolving tablets of Terbutaline sulphate. Various approaches explored in the present work can be applied to achieve quick disintegration, good mouth feel and adequate mechanical strength, which improve patient compliance. Further work can be focused on co processing of various diluents with superdisintegrant. Some herbal superdisintegrant in freeze dried form can be investigated to determine their effect on disintegration time and hardness. To evaluate the effects of fast dissolving tablets in stress conditions, pharmacokinetic study can be performed in diseased state, and to compare with the results obtained in non- diseased state. All the researchers working on Terbutaline sulphate concentrates their research on the disintegration behavior of the tablets using super disintegrants which does not full fill the basic requirements of the mouth dissolving tablets i.e. patient compliance. Industries who want to make a Terbutaline sulphate blindly incorporating insoluble taste masking resins, superdisintegrants for disintegration and trading as mouth dissolving tablet. Due to lots of limitations like hardness, mechanical strength, no ease of manufacturing and most important cost of manufacturing, that’s why, industries concentrate whole emphasis on the use of superdisintegrants and make researchers not to work on mouth dissolving tablets instead moves on to mouth disintegrating tablets. Thus we concentrate on formulating mouth dissolving tablets giving complete dissolution of the formulation with minimum residue. <br />KEYWORDS- Terbutaline sulphate, Migraine, Mouth Dissolving Tablet, Croscarmellose Sodium, Crospovidone, Superdisintegrants.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4f21d661b13beaaea9c73a5a4b8f7dc7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90238323,"asset_id":85586353,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90238323/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85586353"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85586353"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85586353; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85586353]").text(description); $(".js-view-count[data-work-id=85586353]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85586353; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85586353']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85586353, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4f21d661b13beaaea9c73a5a4b8f7dc7" } } $('.js-work-strip[data-work-id=85586353]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85586353,"title":"FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TERBUTALIINE SULFATE","translated_title":"","metadata":{"doi":"10.5281/zenodo.7022693","abstract":"The outcome of present work provides a concrete basis for development of fast dissolving tablets of Terbutaline sulphate. Various approaches explored in the present work can be applied to achieve quick disintegration, good mouth feel and adequate mechanical strength, which improve patient compliance. Further work can be focused on co processing of various diluents with superdisintegrant. Some herbal superdisintegrant in freeze dried form can be investigated to determine their effect on disintegration time and hardness. To evaluate the effects of fast dissolving tablets in stress conditions, pharmacokinetic study can be performed in diseased state, and to compare with the results obtained in non- diseased state. All the researchers working on Terbutaline sulphate concentrates their research on the disintegration behavior of the tablets using super disintegrants which does not full fill the basic requirements of the mouth dissolving tablets i.e. patient compliance. Industries who want to make a Terbutaline sulphate blindly incorporating insoluble taste masking resins, superdisintegrants for disintegration and trading as mouth dissolving tablet. Due to lots of limitations like hardness, mechanical strength, no ease of manufacturing and most important cost of manufacturing, that’s why, industries concentrate whole emphasis on the use of superdisintegrants and make researchers not to work on mouth dissolving tablets instead moves on to mouth disintegrating tablets. Thus we concentrate on formulating mouth dissolving tablets giving complete dissolution of the formulation with minimum residue. \nKEYWORDS- Terbutaline sulphate, Migraine, Mouth Dissolving Tablet, Croscarmellose Sodium, Crospovidone, Superdisintegrants.\n","ai_title_tag":"Mouth Dissolving Tablets of Terbutaline Sulfate: Formulation \u0026 Evaluation"},"translated_abstract":"The outcome of present work provides a concrete basis for development of fast dissolving tablets of Terbutaline sulphate. Various approaches explored in the present work can be applied to achieve quick disintegration, good mouth feel and adequate mechanical strength, which improve patient compliance. Further work can be focused on co processing of various diluents with superdisintegrant. Some herbal superdisintegrant in freeze dried form can be investigated to determine their effect on disintegration time and hardness. To evaluate the effects of fast dissolving tablets in stress conditions, pharmacokinetic study can be performed in diseased state, and to compare with the results obtained in non- diseased state. All the researchers working on Terbutaline sulphate concentrates their research on the disintegration behavior of the tablets using super disintegrants which does not full fill the basic requirements of the mouth dissolving tablets i.e. patient compliance. Industries who want to make a Terbutaline sulphate blindly incorporating insoluble taste masking resins, superdisintegrants for disintegration and trading as mouth dissolving tablet. Due to lots of limitations like hardness, mechanical strength, no ease of manufacturing and most important cost of manufacturing, that’s why, industries concentrate whole emphasis on the use of superdisintegrants and make researchers not to work on mouth dissolving tablets instead moves on to mouth disintegrating tablets. Thus we concentrate on formulating mouth dissolving tablets giving complete dissolution of the formulation with minimum residue. \nKEYWORDS- Terbutaline sulphate, Migraine, Mouth Dissolving Tablet, Croscarmellose Sodium, Crospovidone, Superdisintegrants.\n","internal_url":"https://www.academia.edu/85586353/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE","translated_internal_url":"","created_at":"2022-08-25T03:44:45.752-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90238323,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238323/thumbnails/1.jpg","file_name":"24.IAJPS24082022.pdf","download_url":"https://www.academia.edu/attachments/90238323/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238323/24.IAJPS24082022-libre.pdf?1661429042=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf\u0026Expires=1732784475\u0026Signature=fC0OOsDU7wvSc-JSnLlwKWbQ2-76WDg6x9e2OLQJb~awGIemWT5G7eg3iySiAbLoZ68RhHT2drhcOFHdMaLc3J3zTxNF-QJ4f~S2WS3zOTlc6V0GIwPlRMJgkbcTtPdseCpl12FJFY1m9DNDuIOKRCKloeI67f9ddxmqhSHz9LrJr2szM4MDp7ReAkgL-EsNZH~-CIzV3G0mhfHfuv4I5IuoEacyGx9u2S~azRZcMo9wcCE8hfp4ggcrVbGYuLTDAbtNB01YKGX6gUz08h8bQcffPRuo~X1z3otitvgt-VR~pjZH2L0Z-LbTjdJPybi7qhuw5yJniMG9UiO6lO3Low__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90238323,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238323/thumbnails/1.jpg","file_name":"24.IAJPS24082022.pdf","download_url":"https://www.academia.edu/attachments/90238323/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238323/24.IAJPS24082022-libre.pdf?1661429042=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf\u0026Expires=1732784475\u0026Signature=fC0OOsDU7wvSc-JSnLlwKWbQ2-76WDg6x9e2OLQJb~awGIemWT5G7eg3iySiAbLoZ68RhHT2drhcOFHdMaLc3J3zTxNF-QJ4f~S2WS3zOTlc6V0GIwPlRMJgkbcTtPdseCpl12FJFY1m9DNDuIOKRCKloeI67f9ddxmqhSHz9LrJr2szM4MDp7ReAkgL-EsNZH~-CIzV3G0mhfHfuv4I5IuoEacyGx9u2S~azRZcMo9wcCE8hfp4ggcrVbGYuLTDAbtNB01YKGX6gUz08h8bQcffPRuo~X1z3otitvgt-VR~pjZH2L0Z-LbTjdJPybi7qhuw5yJniMG9UiO6lO3Low__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85540898"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85540898/MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW"><img alt="Research paper thumbnail of MASTECTOMY VS LUMPECTOMY RECURRENCE AND SURVIVAL RATES, A SYSTEMATIC REVIEW" class="work-thumbnail" src="https://attachments.academia-assets.com/90209461/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85540898/MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW">MASTECTOMY VS LUMPECTOMY RECURRENCE AND SURVIVAL RATES, A SYSTEMATIC REVIEW</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Respect to patient preference, a lumpectomy is one of the operations that has been pr...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Respect to patient preference, a lumpectomy is one of the operations that has been practised up to this point. In terms of mortality survival rate, it has both benefits and drawbacks. However, some breast cancer patients may experience a tumour recurrence following a lumpectomy, whether or not radiation was used to treat it.<br />Objectives: This study aims to assess and current evidences regarding overall survival (OS) and oncological outcomes of breast conservative treatment (lumpectomy) versus mastectomy.<br />Methods: For article selection, the PubMed database Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.<br />Conclusion: Half included studies reported equivalent results for both BCT and mastectomy. Yet, 6 studies against 3 were supporting BCT over mastectomy respectively in respect to patient diagnostic status and associated adjuvant treatment. However, BCT is the standard surgical technique for primary breast cancer and meets the preferences of the majority of breast cancer patients in terms of oncological safety and aesthetic outcome.<br />Keywords: breast cancer, lumpectomy, breast conservative treatment, mastectomy, overall survival, recurrence</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f8cef897f759dfc116e93f4970aefc7f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90209461,"asset_id":85540898,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90209461/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85540898"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85540898"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85540898; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85540898]").text(description); $(".js-view-count[data-work-id=85540898]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85540898; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85540898']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85540898, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f8cef897f759dfc116e93f4970aefc7f" } } $('.js-work-strip[data-work-id=85540898]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85540898,"title":"MASTECTOMY VS LUMPECTOMY RECURRENCE AND SURVIVAL RATES, A SYSTEMATIC REVIEW","translated_title":"","metadata":{"doi":"10.5281/zenodo.7020147","abstract":"Background: Respect to patient preference, a lumpectomy is one of the operations that has been practised up to this point. In terms of mortality survival rate, it has both benefits and drawbacks. However, some breast cancer patients may experience a tumour recurrence following a lumpectomy, whether or not radiation was used to treat it.\nObjectives: This study aims to assess and current evidences regarding overall survival (OS) and oncological outcomes of breast conservative treatment (lumpectomy) versus mastectomy.\nMethods: For article selection, the PubMed database Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.\nConclusion: Half included studies reported equivalent results for both BCT and mastectomy. Yet, 6 studies against 3 were supporting BCT over mastectomy respectively in respect to patient diagnostic status and associated adjuvant treatment. However, BCT is the standard surgical technique for primary breast cancer and meets the preferences of the majority of breast cancer patients in terms of oncological safety and aesthetic outcome.\nKeywords: breast cancer, lumpectomy, breast conservative treatment, mastectomy, overall survival, recurrence\n"},"translated_abstract":"Background: Respect to patient preference, a lumpectomy is one of the operations that has been practised up to this point. In terms of mortality survival rate, it has both benefits and drawbacks. However, some breast cancer patients may experience a tumour recurrence following a lumpectomy, whether or not radiation was used to treat it.\nObjectives: This study aims to assess and current evidences regarding overall survival (OS) and oncological outcomes of breast conservative treatment (lumpectomy) versus mastectomy.\nMethods: For article selection, the PubMed database Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.\nConclusion: Half included studies reported equivalent results for both BCT and mastectomy. Yet, 6 studies against 3 were supporting BCT over mastectomy respectively in respect to patient diagnostic status and associated adjuvant treatment. However, BCT is the standard surgical technique for primary breast cancer and meets the preferences of the majority of breast cancer patients in terms of oncological safety and aesthetic outcome.\nKeywords: breast cancer, lumpectomy, breast conservative treatment, mastectomy, overall survival, recurrence\n","internal_url":"https://www.academia.edu/85540898/MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW","translated_internal_url":"","created_at":"2022-08-24T11:17:31.520-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90209461,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90209461/thumbnails/1.jpg","file_name":"23.IAJPS23082022.pdf","download_url":"https://www.academia.edu/attachments/90209461/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90209461/23.IAJPS23082022-libre.pdf?1661368001=\u0026response-content-disposition=attachment%3B+filename%3DMASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf\u0026Expires=1732784475\u0026Signature=SdIyreji6qZK0l4wyghm6MHE-WEHOLraOokB-vtBer1no0D1EflvjdIOx6uUB~wyMJE8G1ONfS5Qysiqhm5Wfv07efbGJKrkkKa-7-nRee4~Ca-flrzVr4JjwgF0aUAf6voAOBV7IYUlfB5o-jgNS~-2BmnsJDXbyIxWXRk5qk8Iqss1wV42naAKjU5IEGLLDkDIzavcW9~-uofkYE1RGV1hCIFgkU5~keQYO8DzXdjqKV4tdZs7uLdXn5451wIyKsl3jDHf5WjEfExuIgsBMBL3S4S1p0MQL7gCjP49f23A4THMZ1Eh16YkP-9H0FpRbWJzwAj2qElTZ3~tkgoubA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90209461,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90209461/thumbnails/1.jpg","file_name":"23.IAJPS23082022.pdf","download_url":"https://www.academia.edu/attachments/90209461/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90209461/23.IAJPS23082022-libre.pdf?1661368001=\u0026response-content-disposition=attachment%3B+filename%3DMASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf\u0026Expires=1732784475\u0026Signature=SdIyreji6qZK0l4wyghm6MHE-WEHOLraOokB-vtBer1no0D1EflvjdIOx6uUB~wyMJE8G1ONfS5Qysiqhm5Wfv07efbGJKrkkKa-7-nRee4~Ca-flrzVr4JjwgF0aUAf6voAOBV7IYUlfB5o-jgNS~-2BmnsJDXbyIxWXRk5qk8Iqss1wV42naAKjU5IEGLLDkDIzavcW9~-uofkYE1RGV1hCIFgkU5~keQYO8DzXdjqKV4tdZs7uLdXn5451wIyKsl3jDHf5WjEfExuIgsBMBL3S4S1p0MQL7gCjP49f23A4THMZ1Eh16YkP-9H0FpRbWJzwAj2qElTZ3~tkgoubA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2495116,"name":"Health \u0026 Medical Sciences","url":"https://www.academia.edu/Documents/in/Health_and_Medical_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85489632"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85489632/FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF HERBAL SCRUB" class="work-thumbnail" src="https://attachments.academia-assets.com/90173333/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85489632/FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB">FORMULATION AND EVALUATION OF HERBAL SCRUB</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, s...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, sebum other secretion Extends the skin and their appendix by chemical topical application. This is useful for making skin charming and beautiful. Cosmetic plays very important role in everyone’s life to make joyful skin. Nowadays herbal cosmeceuticals are in demand due to less or no side effect. Hebal cosmeceutical usually contain plant part which posses antimicrobial, antiaging, antiacne, antioxidant property. The number of research has studied rice benefit namely good nutritional value, resistance to high blood pressure. The problem like blackhead, whiteheads, acne might irritate nowadays here scrubbing become useful. For the healthy skin there is need of cleansing, removing dirt and debris. The current work is based on the formulation and evaluation of herbal facial scrub by using herbal drugs and evaluation is done by using various parameters. Thus prepared formulation use effectively to show the cleansing and glowing action. Using rice flour, lemon juice,Multani mitti, Neem Powder, Haldi, Tulsi, Mint, Carbopol 940, Gram flour, Sodium Benzoate, Sodium Lauryl Sulphate and Water, we Created four different formulation F1, F2, F3 and F4 for scrubbing and whitening. These formulation were then tested for various parameter, including Physical appearance, Homogeneity, Extrudability, Spreadability, Irritability, Washability, Grittiness, Foamability, Viscosity, Stability, Consistency.<br />KEYWORD: Scrubbing, cleansing, herbal, Antiacne, Whitening.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="438bc47df3cd4f67a618b08012c161cd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90173333,"asset_id":85489632,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90173333/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85489632"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85489632"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85489632; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85489632]").text(description); $(".js-view-count[data-work-id=85489632]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85489632; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85489632']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85489632, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "438bc47df3cd4f67a618b08012c161cd" } } $('.js-work-strip[data-work-id=85489632]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85489632,"title":"FORMULATION AND EVALUATION OF HERBAL SCRUB","translated_title":"","metadata":{"doi":"10.5281/zenodo.7018144","abstract":"For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, sebum other secretion Extends the skin and their appendix by chemical topical application. This is useful for making skin charming and beautiful. Cosmetic plays very important role in everyone’s life to make joyful skin. Nowadays herbal cosmeceuticals are in demand due to less or no side effect. Hebal cosmeceutical usually contain plant part which posses antimicrobial, antiaging, antiacne, antioxidant property. The number of research has studied rice benefit namely good nutritional value, resistance to high blood pressure. The problem like blackhead, whiteheads, acne might irritate nowadays here scrubbing become useful. For the healthy skin there is need of cleansing, removing dirt and debris. The current work is based on the formulation and evaluation of herbal facial scrub by using herbal drugs and evaluation is done by using various parameters. Thus prepared formulation use effectively to show the cleansing and glowing action. Using rice flour, lemon juice,Multani mitti, Neem Powder, Haldi, Tulsi, Mint, Carbopol 940, Gram flour, Sodium Benzoate, Sodium Lauryl Sulphate and Water, we Created four different formulation F1, F2, F3 and F4 for scrubbing and whitening. These formulation were then tested for various parameter, including Physical appearance, Homogeneity, Extrudability, Spreadability, Irritability, Washability, Grittiness, Foamability, Viscosity, Stability, Consistency.\nKEYWORD: Scrubbing, cleansing, herbal, Antiacne, Whitening. \n"},"translated_abstract":"For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, sebum other secretion Extends the skin and their appendix by chemical topical application. This is useful for making skin charming and beautiful. Cosmetic plays very important role in everyone’s life to make joyful skin. Nowadays herbal cosmeceuticals are in demand due to less or no side effect. Hebal cosmeceutical usually contain plant part which posses antimicrobial, antiaging, antiacne, antioxidant property. The number of research has studied rice benefit namely good nutritional value, resistance to high blood pressure. The problem like blackhead, whiteheads, acne might irritate nowadays here scrubbing become useful. For the healthy skin there is need of cleansing, removing dirt and debris. The current work is based on the formulation and evaluation of herbal facial scrub by using herbal drugs and evaluation is done by using various parameters. Thus prepared formulation use effectively to show the cleansing and glowing action. Using rice flour, lemon juice,Multani mitti, Neem Powder, Haldi, Tulsi, Mint, Carbopol 940, Gram flour, Sodium Benzoate, Sodium Lauryl Sulphate and Water, we Created four different formulation F1, F2, F3 and F4 for scrubbing and whitening. These formulation were then tested for various parameter, including Physical appearance, Homogeneity, Extrudability, Spreadability, Irritability, Washability, Grittiness, Foamability, Viscosity, Stability, Consistency.\nKEYWORD: Scrubbing, cleansing, herbal, Antiacne, Whitening. \n","internal_url":"https://www.academia.edu/85489632/FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB","translated_internal_url":"","created_at":"2022-08-23T22:37:47.737-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90173333,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90173333/thumbnails/1.jpg","file_name":"22.IAJPS22082022.pdf","download_url":"https://www.academia.edu/attachments/90173333/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90173333/22.IAJPS22082022-libre.pdf?1661322957=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf\u0026Expires=1732784475\u0026Signature=b64BNuQRVvgJumvUpOnFR4O7fVPMhBo5ggtCS8U8rEuBhVdfl3jPZavF0CJhvGiMNX~tf0OYIj33Z8-~MQ8ZTdE74Gk6eL9GMkmUr6aGlfQo0TNUqH-uvtLucPwTplZw~lHidybmyLSV4Y55Wqrdf38DeY8WRvVYAUiXSVQsgLqkYS073L3ZTP2~5m6xH2vNn5~ZSYDNjC2L0-qV0PsO6FSFOwd5M964T~GQ0no0bk8oUdbt9G96iFF9DknrUAHlm8QWyPbeK5bHKyRdIPi3TT2qXpv4w1yJkw7xsuff1N472nIrykkwn2OO3SHZNfGi3wdb17zNuK5g8NO3ipndbg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90173333,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90173333/thumbnails/1.jpg","file_name":"22.IAJPS22082022.pdf","download_url":"https://www.academia.edu/attachments/90173333/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90173333/22.IAJPS22082022-libre.pdf?1661322957=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf\u0026Expires=1732784475\u0026Signature=b64BNuQRVvgJumvUpOnFR4O7fVPMhBo5ggtCS8U8rEuBhVdfl3jPZavF0CJhvGiMNX~tf0OYIj33Z8-~MQ8ZTdE74Gk6eL9GMkmUr6aGlfQo0TNUqH-uvtLucPwTplZw~lHidybmyLSV4Y55Wqrdf38DeY8WRvVYAUiXSVQsgLqkYS073L3ZTP2~5m6xH2vNn5~ZSYDNjC2L0-qV0PsO6FSFOwd5M964T~GQ0no0bk8oUdbt9G96iFF9DknrUAHlm8QWyPbeK5bHKyRdIPi3TT2qXpv4w1yJkw7xsuff1N472nIrykkwn2OO3SHZNfGi3wdb17zNuK5g8NO3ipndbg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85431600"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85431600/FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM" class="work-thumbnail" src="https://attachments.academia-assets.com/90131192/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85431600/FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM">FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and HPMC K4M by direct compression method.The IR spectra revealed that, there was no interaction between polymers and drug. All polymers used were compatible with drug.All the prepared tablets were in acceptable range of weight variation, hardness, thickness, friability and drug content as per pharmacopoeial specification.The surface pH of prepared Buccal Patches was in the range of salivary pH, suggested that prepared tablets could be used without risk of mucosal irritation.All the Buccal Patches showed good residence time of 7.2 H to >10 h, indicated good adhesive capacity of polymers used.The CCD was used to find out the effect of independent varibles on the dependable variables. The result of CCD revealed that the locustbean gum and HPMC K4M have significant effect on the mucoadhesion strenth, swelling index, the drug release at 1 h and drug release at 8 h. The observed independent variables were found to be very close to predicted values of optimized formulation which demonstrates the feasibility of the optimization procedure in successful development of buccal tablet containing losartan potassium by using locustbean gum and HPMC K4M. The drug release form the optimized formula was found to be following the zero order kinetics and n value range of the Peppas equation is 0.521, which indicates fickian diffusion mechanism. Thus the release of drug from the dosage form was found to be time dependent.The stability studies revealed that there was no significant change in buccal tablet properties with aging at different storage conditions.Hence, the mucoadhesive Buccal Patches of losartan potassium can be prepared with enhanced bioavailability and prolonged therapeutic effect for the better management of hyper tension.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="dcff74c6b081a0d8f23ffef6576391fb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90131192,"asset_id":85431600,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90131192/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85431600"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85431600"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85431600; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85431600]").text(description); $(".js-view-count[data-work-id=85431600]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85431600; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85431600']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85431600, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "dcff74c6b081a0d8f23ffef6576391fb" } } $('.js-work-strip[data-work-id=85431600]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85431600,"title":"FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM","translated_title":"","metadata":{"doi":"10.5281/zenodo.7016528","abstract":"The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and HPMC K4M by direct compression method.The IR spectra revealed that, there was no interaction between polymers and drug. All polymers used were compatible with drug.All the prepared tablets were in acceptable range of weight variation, hardness, thickness, friability and drug content as per pharmacopoeial specification.The surface pH of prepared Buccal Patches was in the range of salivary pH, suggested that prepared tablets could be used without risk of mucosal irritation.All the Buccal Patches showed good residence time of 7.2 H to \u003e10 h, indicated good adhesive capacity of polymers used.The CCD was used to find out the effect of independent varibles on the dependable variables. The result of CCD revealed that the locustbean gum and HPMC K4M have significant effect on the mucoadhesion strenth, swelling index, the drug release at 1 h and drug release at 8 h. The observed independent variables were found to be very close to predicted values of optimized formulation which demonstrates the feasibility of the optimization procedure in successful development of buccal tablet containing losartan potassium by using locustbean gum and HPMC K4M. The drug release form the optimized formula was found to be following the zero order kinetics and n value range of the Peppas equation is 0.521, which indicates fickian diffusion mechanism. Thus the release of drug from the dosage form was found to be time dependent.The stability studies revealed that there was no significant change in buccal tablet properties with aging at different storage conditions.Hence, the mucoadhesive Buccal Patches of losartan potassium can be prepared with enhanced bioavailability and prolonged therapeutic effect for the better management of hyper tension."},"translated_abstract":"The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and HPMC K4M by direct compression method.The IR spectra revealed that, there was no interaction between polymers and drug. All polymers used were compatible with drug.All the prepared tablets were in acceptable range of weight variation, hardness, thickness, friability and drug content as per pharmacopoeial specification.The surface pH of prepared Buccal Patches was in the range of salivary pH, suggested that prepared tablets could be used without risk of mucosal irritation.All the Buccal Patches showed good residence time of 7.2 H to \u003e10 h, indicated good adhesive capacity of polymers used.The CCD was used to find out the effect of independent varibles on the dependable variables. The result of CCD revealed that the locustbean gum and HPMC K4M have significant effect on the mucoadhesion strenth, swelling index, the drug release at 1 h and drug release at 8 h. The observed independent variables were found to be very close to predicted values of optimized formulation which demonstrates the feasibility of the optimization procedure in successful development of buccal tablet containing losartan potassium by using locustbean gum and HPMC K4M. The drug release form the optimized formula was found to be following the zero order kinetics and n value range of the Peppas equation is 0.521, which indicates fickian diffusion mechanism. Thus the release of drug from the dosage form was found to be time dependent.The stability studies revealed that there was no significant change in buccal tablet properties with aging at different storage conditions.Hence, the mucoadhesive Buccal Patches of losartan potassium can be prepared with enhanced bioavailability and prolonged therapeutic effect for the better management of hyper tension.","internal_url":"https://www.academia.edu/85431600/FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM","translated_internal_url":"","created_at":"2022-08-23T03:19:11.399-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":38709673,"work_id":85431600,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":2760873,"email":"n***a@gmail.com","display_order":1,"name":"Nansri Saha","title":"FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM"},{"id":38709674,"work_id":85431600,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":7263053,"email":"r***9@gmail.com","display_order":2,"name":"Kummari Raju","title":"FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM"}],"downloadable_attachments":[{"id":90131192,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131192/thumbnails/1.jpg","file_name":"21.IAJPS21082022.pdf","download_url":"https://www.academia.edu/attachments/90131192/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131192/21.IAJPS21082022-libre.pdf?1661251264=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf\u0026Expires=1732810433\u0026Signature=WzfuR~tY02k32zlB1L7qyYyGeb9o9pMjJmC0TpDAT~gtXqud8jZgmycDnly3UagX7FEtlocUEEXfOzwj8GhWvtBD9paodqDFfHgrfNdJy22HPROLSmA9LTIfg7hZBUGk8dWpFOswS8GotG-ylY4NcuVHMhlJdQXscioFZGXQubRSx2efyLKk-sUTwBHP-S-P9zuYCVatTrytta6uEUoUaJ3WpXxOkcmbqmD3~JhNjs5YyJvVtwci1NzS6YFMEluXde3ZUDuk18KJ7OKyKvZNXR7hosKAla0Sec1xmDrmhmfVn52n4OoqpsHkss9CXfR5zLSCJeMXchkhtPIDT85u1Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM","translated_slug":"","page_count":22,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"NERLa0ZVemo3b2V2ZnhvclJSV1hLVkIySmZoWHhUTGdkM0RrRkZzclVQUHBsQnlCZkE1dVlTdU5PNzdNb0hmSy0tWFl5NXlHVmV4c2ZHRk5mbW45TFFpZz09--55aa7bd5a34b9da9e36f7e4857b57c514dec1744"},"attachments":[{"id":90131192,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131192/thumbnails/1.jpg","file_name":"21.IAJPS21082022.pdf","download_url":"https://www.academia.edu/attachments/90131192/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131192/21.IAJPS21082022-libre.pdf?1661251264=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf\u0026Expires=1732810433\u0026Signature=WzfuR~tY02k32zlB1L7qyYyGeb9o9pMjJmC0TpDAT~gtXqud8jZgmycDnly3UagX7FEtlocUEEXfOzwj8GhWvtBD9paodqDFfHgrfNdJy22HPROLSmA9LTIfg7hZBUGk8dWpFOswS8GotG-ylY4NcuVHMhlJdQXscioFZGXQubRSx2efyLKk-sUTwBHP-S-P9zuYCVatTrytta6uEUoUaJ3WpXxOkcmbqmD3~JhNjs5YyJvVtwci1NzS6YFMEluXde3ZUDuk18KJ7OKyKvZNXR7hosKAla0Sec1xmDrmhmfVn52n4OoqpsHkss9CXfR5zLSCJeMXchkhtPIDT85u1Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85431427"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85431427/POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE"><img alt="Research paper thumbnail of POST COVID DEPRESSION: A REVIEW OF LITERATURE" class="work-thumbnail" src="https://attachments.academia-assets.com/90131073/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85431427/POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE">POST COVID DEPRESSION: A REVIEW OF LITERATURE</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pai...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pain, headache, diarrhea, rhinorrhea, loss of smell and taste. In addition, there are more and more reports of mental health problems in people who have survived SARS-CoV-2 infection. The most frequently described mental disorders are major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorders (OCD) and insomnia. MDD is hypothesized to be an active inflammatory process with elevated pro- and anti-inflammatory cytokines and oxidative stress. Depression is a leading cause of disability globally. Accordingly, depressive symptoms and clinically-significant depression in post-COVID-19 syndrome may have severe implications as it relates to quality-of-life outcomes. There is also a lack of comprehensive studies directly linking MDD and its biomarkers to COVID-19. Furthermore, it remains to be determined whether the high frequency of depression among individuals with post-COVID-19 syndrome is a long-term consequence of the viral infection or a result of the social and/or economic outcomes of the pandemic. <br />Keywords: Corona virus; Depression; Post Covid; Major Depressive Episode.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2b05bc5697eadccd3b6f11963e94ed22" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90131073,"asset_id":85431427,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90131073/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85431427"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85431427"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85431427; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85431427]").text(description); $(".js-view-count[data-work-id=85431427]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85431427; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85431427']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85431427, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2b05bc5697eadccd3b6f11963e94ed22" } } $('.js-work-strip[data-work-id=85431427]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85431427,"title":"POST COVID DEPRESSION: A REVIEW OF LITERATURE","translated_title":"","metadata":{"doi":"10.5281/zenodo.7016526","abstract":"The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pain, headache, diarrhea, rhinorrhea, loss of smell and taste. In addition, there are more and more reports of mental health problems in people who have survived SARS-CoV-2 infection. The most frequently described mental disorders are major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorders (OCD) and insomnia. MDD is hypothesized to be an active inflammatory process with elevated pro- and anti-inflammatory cytokines and oxidative stress. Depression is a leading cause of disability globally. Accordingly, depressive symptoms and clinically-significant depression in post-COVID-19 syndrome may have severe implications as it relates to quality-of-life outcomes. There is also a lack of comprehensive studies directly linking MDD and its biomarkers to COVID-19. Furthermore, it remains to be determined whether the high frequency of depression among individuals with post-COVID-19 syndrome is a long-term consequence of the viral infection or a result of the social and/or economic outcomes of the pandemic. \nKeywords: Corona virus; Depression; Post Covid; Major Depressive Episode.\n"},"translated_abstract":"The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pain, headache, diarrhea, rhinorrhea, loss of smell and taste. In addition, there are more and more reports of mental health problems in people who have survived SARS-CoV-2 infection. The most frequently described mental disorders are major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorders (OCD) and insomnia. MDD is hypothesized to be an active inflammatory process with elevated pro- and anti-inflammatory cytokines and oxidative stress. Depression is a leading cause of disability globally. Accordingly, depressive symptoms and clinically-significant depression in post-COVID-19 syndrome may have severe implications as it relates to quality-of-life outcomes. There is also a lack of comprehensive studies directly linking MDD and its biomarkers to COVID-19. Furthermore, it remains to be determined whether the high frequency of depression among individuals with post-COVID-19 syndrome is a long-term consequence of the viral infection or a result of the social and/or economic outcomes of the pandemic. \nKeywords: Corona virus; Depression; Post Covid; Major Depressive Episode.\n","internal_url":"https://www.academia.edu/85431427/POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE","translated_internal_url":"","created_at":"2022-08-23T03:16:53.796-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90131073,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131073/thumbnails/1.jpg","file_name":"20.IAJPS20082022.pdf","download_url":"https://www.academia.edu/attachments/90131073/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"POST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131073/20.IAJPS20082022-libre.pdf?1661251258=\u0026response-content-disposition=attachment%3B+filename%3DPOST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf\u0026Expires=1732810433\u0026Signature=T9s3JJc7~jGRRMMHL-C0CwIRy6kZs74naLQelzsI8vrz0QkQY6kIX1PKJSKL-hx3r06lt~KaYzcJIKUi3-mSt4Aa3rGbkVZ4qlm-Q~kEuG2Zzq-hxPnJTjHDxCt8ReP~KxCIHk3MqxAwi9pG8rArf6OV0Bv36opswppV8BDWSsv6L4LuytQGToEo2fh~K1MDQUKLKzTvGEgyM8T9BF4YYcXDvN7Ww5~jsDs4SPNN7~qqmUDcIUojPINBL58cTRUmJb9rqM9jTb7~L6k~vQRJm1kvBaGwrjM8Qr6uoZX7HriJyC9~BC0J92RKdOtQ7j0nejX2BdM9Vx8886m3dKJFpw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE","translated_slug":"","page_count":3,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"RlNQMDhBTityY0JWc3pLVHhvcGlnTFliaXk2bTFtV3JmWTBJYlR3QU1ZMnpFdDk2Rm1XZ3A2bXppWXJKTFJQZC0tcndSTXZRaWVZK0lDZzl6THFwNldUUT09--808f1c5c14933cd472fa67fc26628bd2e0b040f6"},"attachments":[{"id":90131073,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131073/thumbnails/1.jpg","file_name":"20.IAJPS20082022.pdf","download_url":"https://www.academia.edu/attachments/90131073/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"POST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131073/20.IAJPS20082022-libre.pdf?1661251258=\u0026response-content-disposition=attachment%3B+filename%3DPOST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf\u0026Expires=1732810433\u0026Signature=T9s3JJc7~jGRRMMHL-C0CwIRy6kZs74naLQelzsI8vrz0QkQY6kIX1PKJSKL-hx3r06lt~KaYzcJIKUi3-mSt4Aa3rGbkVZ4qlm-Q~kEuG2Zzq-hxPnJTjHDxCt8ReP~KxCIHk3MqxAwi9pG8rArf6OV0Bv36opswppV8BDWSsv6L4LuytQGToEo2fh~K1MDQUKLKzTvGEgyM8T9BF4YYcXDvN7Ww5~jsDs4SPNN7~qqmUDcIUojPINBL58cTRUmJb9rqM9jTb7~L6k~vQRJm1kvBaGwrjM8Qr6uoZX7HriJyC9~BC0J92RKdOtQ7j0nejX2BdM9Vx8886m3dKJFpw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85431255"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85431255/EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA"><img alt="Research paper thumbnail of EFFECT OF MARIJUANA USE FOR PAIN RELIEF IN PATIENTS WITH FIBROMYALGIA" class="work-thumbnail" src="https://attachments.academia-assets.com/90130946/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85431255/EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA">EFFECT OF MARIJUANA USE FOR PAIN RELIEF IN PATIENTS WITH FIBROMYALGIA</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. H...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. Herbal cannabis or marijuana has been used for the treatment of pain for centuries. This is noteworthy that in recent times its use has been mostly outside traditional medicine. In this study, we audit and conducted a review of the studies and patients with confirmed history of fibromyalgia and the effects of marijuana (Medical Cannabis-MC) for the pain relief, was documented and discussed. Despite lingering controversy, the use of botanical cannabis for medicinal purposes represents the revival of a plant with historical significance reemerging in present day health care. MC appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.<br />Keywords: Fibromyalgia; Marijuana; Medical Cannabis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b8c9479f9b243ef74d0197be7bdf772e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90130946,"asset_id":85431255,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90130946/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85431255"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85431255"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85431255; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85431255]").text(description); $(".js-view-count[data-work-id=85431255]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85431255; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85431255']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85431255, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b8c9479f9b243ef74d0197be7bdf772e" } } $('.js-work-strip[data-work-id=85431255]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85431255,"title":"EFFECT OF MARIJUANA USE FOR PAIN RELIEF IN PATIENTS WITH FIBROMYALGIA","translated_title":"","metadata":{"doi":"10.5281/zenodo.7016509","abstract":"There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. Herbal cannabis or marijuana has been used for the treatment of pain for centuries. This is noteworthy that in recent times its use has been mostly outside traditional medicine. In this study, we audit and conducted a review of the studies and patients with confirmed history of fibromyalgia and the effects of marijuana (Medical Cannabis-MC) for the pain relief, was documented and discussed. Despite lingering controversy, the use of botanical cannabis for medicinal purposes represents the revival of a plant with historical significance reemerging in present day health care. MC appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.\nKeywords: Fibromyalgia; Marijuana; Medical Cannabis.\n"},"translated_abstract":"There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. Herbal cannabis or marijuana has been used for the treatment of pain for centuries. This is noteworthy that in recent times its use has been mostly outside traditional medicine. In this study, we audit and conducted a review of the studies and patients with confirmed history of fibromyalgia and the effects of marijuana (Medical Cannabis-MC) for the pain relief, was documented and discussed. Despite lingering controversy, the use of botanical cannabis for medicinal purposes represents the revival of a plant with historical significance reemerging in present day health care. MC appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.\nKeywords: Fibromyalgia; Marijuana; Medical Cannabis.\n","internal_url":"https://www.academia.edu/85431255/EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA","translated_internal_url":"","created_at":"2022-08-23T03:14:01.339-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90130946,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90130946/thumbnails/1.jpg","file_name":"19.IAJPS19082022.pdf","download_url":"https://www.academia.edu/attachments/90130946/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90130946/19.IAJPS19082022-libre.pdf?1661251276=\u0026response-content-disposition=attachment%3B+filename%3DEFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf\u0026Expires=1732810433\u0026Signature=XSdo0Vy~xJ0ycHtd7kLKr6n18iCjy7Yu4knRlql~5c~mnzwS~wyiwRCBlh4G2lmHN~LaJoHv6rzLMyKQOKlFdyn~hZwDFx5LYJkexinbT9VV30f3S0c-0AJJhf7aL6VVZ2szPn8UkcG7F7BdHEEcwi0C4xHF5lxSzryOq-8F0J7WXy27QPfG6R1RFUolJyUUYFY5jJWmQguOmob502E7F-SjJP-dcMiqbRXaj29~-w7qnQnZ8gDHy42cb~y3~kxHiDjxKu-mplTRxpOeNFaUVlPHQST5W8ReByarOKzZ8X57InhkLYFYCo~vDFd1n6dp6ojGFuxvuO3jPOULSbbdKQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA","translated_slug":"","page_count":4,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"aytzVXlDYlI4R3dMY2RkaHA3VmZjY2N3TnN1THZHVWZ1RjN0anB6MUdTSGVicmNadnYwaWhwdTJkY2pUZ0k2ai0tYWZZWW9QN2xaOEd4a08yUnlhcWkzUT09--fc68acc4d8337b44d05761503b19c98d0ae4a450"},"attachments":[{"id":90130946,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90130946/thumbnails/1.jpg","file_name":"19.IAJPS19082022.pdf","download_url":"https://www.academia.edu/attachments/90130946/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90130946/19.IAJPS19082022-libre.pdf?1661251276=\u0026response-content-disposition=attachment%3B+filename%3DEFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf\u0026Expires=1732810433\u0026Signature=XSdo0Vy~xJ0ycHtd7kLKr6n18iCjy7Yu4knRlql~5c~mnzwS~wyiwRCBlh4G2lmHN~LaJoHv6rzLMyKQOKlFdyn~hZwDFx5LYJkexinbT9VV30f3S0c-0AJJhf7aL6VVZ2szPn8UkcG7F7BdHEEcwi0C4xHF5lxSzryOq-8F0J7WXy27QPfG6R1RFUolJyUUYFY5jJWmQguOmob502E7F-SjJP-dcMiqbRXaj29~-w7qnQnZ8gDHy42cb~y3~kxHiDjxKu-mplTRxpOeNFaUVlPHQST5W8ReByarOKzZ8X57InhkLYFYCo~vDFd1n6dp6ojGFuxvuO3jPOULSbbdKQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85132256"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85132256/A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL"><img alt="Research paper thumbnail of A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG- DRUG INTERACTIONS IN CARDIAC PATIENTS AT A TERTIARY CARE HOSPITAL" class="work-thumbnail" src="https://attachments.academia-assets.com/89926329/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85132256/A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL">A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG- DRUG INTERACTIONS IN CARDIAC PATIENTS AT A TERTIARY CARE HOSPITAL</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in card...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in cardiac patients. Method: This study was carried out for duration of 6 months at the inpatient department of General medicine in Osmania general hospital, Afzalgunj, Hyderabad. The data of 75 patients was collected and the frequently occurring drug-drug interactions among the selected patients were noted. <br />Results: The study identified various drug-drug interactions in cardiac patients with minor drug interactions being more common (52%). The subjects were distributed on the basis of age, gender, diagnosis and number of drugs used. The cardiovascular drugs prescribed were Anticoagulants (25.7%), Anti hyper lipidemics (21.3%), Diuretics (16.9%) and Calcium channel blockers (13.2%), ACE-inhibitors (9.5%), Vasodilators (6.6%) and Angiotensin receptor blockers (6.6%). <br />Conclusion: The present study shows that DDI’s are frequent among hospitalized cardiac patients and highlights the need to screen prescriptions of cardiovascular patients for DDI’s, as this helps in detection and prevention of possible adverse drug interactions.Thus, this study assists in understanding the factors associated with DDI’s that can help in safe and effective use of drugs in future. <br />Key words: Drug-drug interactions, cardiovascular, patients, adverse drug.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="21039455981591ed20e0e27ccf4caa6f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89926329,"asset_id":85132256,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89926329/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85132256"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85132256"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85132256; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85132256]").text(description); $(".js-view-count[data-work-id=85132256]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85132256; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85132256']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85132256, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "21039455981591ed20e0e27ccf4caa6f" } } $('.js-work-strip[data-work-id=85132256]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85132256,"title":"A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG- DRUG INTERACTIONS IN CARDIAC PATIENTS AT A TERTIARY CARE HOSPITAL","translated_title":"","metadata":{"doi":"10.5281/zenodo.7009588","abstract":"Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in cardiac patients. Method: This study was carried out for duration of 6 months at the inpatient department of General medicine in Osmania general hospital, Afzalgunj, Hyderabad. The data of 75 patients was collected and the frequently occurring drug-drug interactions among the selected patients were noted. \nResults: The study identified various drug-drug interactions in cardiac patients with minor drug interactions being more common (52%). The subjects were distributed on the basis of age, gender, diagnosis and number of drugs used. The cardiovascular drugs prescribed were Anticoagulants (25.7%), Anti hyper lipidemics (21.3%), Diuretics (16.9%) and Calcium channel blockers (13.2%), ACE-inhibitors (9.5%), Vasodilators (6.6%) and Angiotensin receptor blockers (6.6%). \nConclusion: The present study shows that DDI’s are frequent among hospitalized cardiac patients and highlights the need to screen prescriptions of cardiovascular patients for DDI’s, as this helps in detection and prevention of possible adverse drug interactions.Thus, this study assists in understanding the factors associated with DDI’s that can help in safe and effective use of drugs in future. \nKey words: Drug-drug interactions, cardiovascular, patients, adverse drug. \n"},"translated_abstract":"Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in cardiac patients. Method: This study was carried out for duration of 6 months at the inpatient department of General medicine in Osmania general hospital, Afzalgunj, Hyderabad. The data of 75 patients was collected and the frequently occurring drug-drug interactions among the selected patients were noted. \nResults: The study identified various drug-drug interactions in cardiac patients with minor drug interactions being more common (52%). The subjects were distributed on the basis of age, gender, diagnosis and number of drugs used. The cardiovascular drugs prescribed were Anticoagulants (25.7%), Anti hyper lipidemics (21.3%), Diuretics (16.9%) and Calcium channel blockers (13.2%), ACE-inhibitors (9.5%), Vasodilators (6.6%) and Angiotensin receptor blockers (6.6%). \nConclusion: The present study shows that DDI’s are frequent among hospitalized cardiac patients and highlights the need to screen prescriptions of cardiovascular patients for DDI’s, as this helps in detection and prevention of possible adverse drug interactions.Thus, this study assists in understanding the factors associated with DDI’s that can help in safe and effective use of drugs in future. \nKey words: Drug-drug interactions, cardiovascular, patients, adverse drug. \n","internal_url":"https://www.academia.edu/85132256/A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL","translated_internal_url":"","created_at":"2022-08-19T05:00:28.079-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89926329,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89926329/thumbnails/1.jpg","file_name":"18.IAJPS18082022.pdf","download_url":"https://www.academia.edu/attachments/89926329/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89926329/18.IAJPS18082022-libre.pdf?1660910729=\u0026response-content-disposition=attachment%3B+filename%3DA_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf\u0026Expires=1732784475\u0026Signature=Zs2ngrlsFHt2YGh6lTs5iFW0RfTrYjusi9C8HocTOkPB7E301p2D67f1-K8uMAcOiwVIuiP91mieLKFnM0Tp4I0xFO3rdFWardlq1Mnyix3Alo4LZ8Q0zTGa2Ob9W2~0GkjF1I-95PjOyiBo8l8q2zOSd7qHAXdAG8pjRpYQaLKhL-r6NYZ0GdRm8Nizelxc2ir3hmNG7~hXY0iCRHJV~HJmJfBLvv36CDiDcUqNkLVRI7xCCGL2JFuDYDnN1XjXsAYAGR4QX-fwzDZvtJ42wAtlkTOvGF8daCuvhXntfRQ61YzhkJhC2Mu997QV1Gbb443mkyMXi-T2fDaDJu1~gw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89926329,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89926329/thumbnails/1.jpg","file_name":"18.IAJPS18082022.pdf","download_url":"https://www.academia.edu/attachments/89926329/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89926329/18.IAJPS18082022-libre.pdf?1660910729=\u0026response-content-disposition=attachment%3B+filename%3DA_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf\u0026Expires=1732784475\u0026Signature=Zs2ngrlsFHt2YGh6lTs5iFW0RfTrYjusi9C8HocTOkPB7E301p2D67f1-K8uMAcOiwVIuiP91mieLKFnM0Tp4I0xFO3rdFWardlq1Mnyix3Alo4LZ8Q0zTGa2Ob9W2~0GkjF1I-95PjOyiBo8l8q2zOSd7qHAXdAG8pjRpYQaLKhL-r6NYZ0GdRm8Nizelxc2ir3hmNG7~hXY0iCRHJV~HJmJfBLvv36CDiDcUqNkLVRI7xCCGL2JFuDYDnN1XjXsAYAGR4QX-fwzDZvtJ42wAtlkTOvGF8daCuvhXntfRQ61YzhkJhC2Mu997QV1Gbb443mkyMXi-T2fDaDJu1~gw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85132056"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85132056/COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_"><img alt="Research paper thumbnail of COMPETITIVE REPLACEMENT OF OBNOXIOUS WEEDS PARTHENIUM HYSTEROPHORUS THROUGH SOME INDIGENOUS, TRADITIONAL & MEDICINAL WILD WEEDS, IN ITS NATURAL HABITAT OF MALWA REGION, MADHYA PRADESH (INDIA)." class="work-thumbnail" src="https://attachments.academia-assets.com/90011439/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85132056/COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_">COMPETITIVE REPLACEMENT OF OBNOXIOUS WEEDS PARTHENIUM HYSTEROPHORUS THROUGH SOME INDIGENOUS, TRADITIONAL & MEDICINAL WILD WEEDS, IN ITS NATURAL HABITAT OF MALWA REGION, MADHYA PRADESH (INDIA).</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A field experiment has been conducted to assess the potential of some medicinally important weed ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A field experiment has been conducted to assess the potential of some medicinally important weed plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera on the removal of Congress grass. Parthenium necessary grass evil in herbs; it can cause toxic effects and serious diseases on human and animal health. Parthenium hysterophorous is a strong intraspecific competitor for native natural weeds and all herbaceous plants. It is a worldwide problem because native herbaceous plants reduce day by day through intraspecific competitive activity. The authors have traced and surveyed this problem and selected local native plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera, and conducted experiments for three consecutive years (2009, 2010, and 2011) in the Malwa region of Madhya Pradesh India. During the three years of the study period, observed (20) significant reduction in the density of obnoxious Parthenium weed by producing fast competition through selected all three native weeds and respectively by increasing the density of C. occidentalis (5.84) < C. tora (5.1) < A. aspera (3.3). <br />Keywords: Achyranthus aspera, Cassia tora, Cassia occidentalis, Congress grass, Parthenium, and Obnoxious weeds.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9569e79b32c2135bbdad27f692d9bd3b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90011439,"asset_id":85132056,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90011439/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85132056"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85132056"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85132056; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85132056]").text(description); $(".js-view-count[data-work-id=85132056]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85132056; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85132056']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85132056, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9569e79b32c2135bbdad27f692d9bd3b" } } $('.js-work-strip[data-work-id=85132056]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85132056,"title":"COMPETITIVE REPLACEMENT OF OBNOXIOUS WEEDS PARTHENIUM HYSTEROPHORUS THROUGH SOME INDIGENOUS, TRADITIONAL \u0026 MEDICINAL WILD WEEDS, IN ITS NATURAL HABITAT OF MALWA REGION, MADHYA PRADESH (INDIA).","translated_title":"","metadata":{"doi":"10.5281/zenodo.7009368","abstract":"A field experiment has been conducted to assess the potential of some medicinally important weed plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera on the removal of Congress grass. Parthenium necessary grass evil in herbs; it can cause toxic effects and serious diseases on human and animal health. Parthenium hysterophorous is a strong intraspecific competitor for native natural weeds and all herbaceous plants. It is a worldwide problem because native herbaceous plants reduce day by day through intraspecific competitive activity. The authors have traced and surveyed this problem and selected local native plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera, and conducted experiments for three consecutive years (2009, 2010, and 2011) in the Malwa region of Madhya Pradesh India. During the three years of the study period, observed (20) significant reduction in the density of obnoxious Parthenium weed by producing fast competition through selected all three native weeds and respectively by increasing the density of C. occidentalis (5.84) \u003c C. tora (5.1) \u003c A. aspera (3.3). \nKeywords: Achyranthus aspera, Cassia tora, Cassia occidentalis, Congress grass, Parthenium, and Obnoxious weeds.\n"},"translated_abstract":"A field experiment has been conducted to assess the potential of some medicinally important weed plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera on the removal of Congress grass. Parthenium necessary grass evil in herbs; it can cause toxic effects and serious diseases on human and animal health. Parthenium hysterophorous is a strong intraspecific competitor for native natural weeds and all herbaceous plants. It is a worldwide problem because native herbaceous plants reduce day by day through intraspecific competitive activity. The authors have traced and surveyed this problem and selected local native plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera, and conducted experiments for three consecutive years (2009, 2010, and 2011) in the Malwa region of Madhya Pradesh India. During the three years of the study period, observed (20) significant reduction in the density of obnoxious Parthenium weed by producing fast competition through selected all three native weeds and respectively by increasing the density of C. occidentalis (5.84) \u003c C. tora (5.1) \u003c A. aspera (3.3). \nKeywords: Achyranthus aspera, Cassia tora, Cassia occidentalis, Congress grass, Parthenium, and Obnoxious weeds.\n","internal_url":"https://www.academia.edu/85132056/COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_","translated_internal_url":"","created_at":"2022-08-19T04:57:28.515-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90011439,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90011439/thumbnails/1.jpg","file_name":"17.IAJPS17082022.pdf","download_url":"https://www.academia.edu/attachments/90011439/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90011439/17.IAJPS17082022-libre.pdf?1661068504=\u0026response-content-disposition=attachment%3B+filename%3DCOMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf\u0026Expires=1732784476\u0026Signature=SB8KowC9GDnVABR1TiKgiOE0azvt~a1i2DrPNGiRKMHUc7C3lBLdceefol3AjJ3OA0frt8daaQyzaeA7BLwHRHUyZZYmttTGAg76mFn1C2ynRGXUyD4zFiS3ztPl2xhI3OzcNeidTVKef2HO3VKwkW2ycMxgccMieyL9jfKQ6WTdEA5dAYH6TgaZPl46LmMCmsKl3uI0s8HoRz3kA-EdlFVRZ~9~lp0bXzO8Us0B2K1Vlrfnnhu~1pvmE6ZIbE5eMIky1hq8C-mX~KD1BnIUI34W3krdZhnf0FFuX8qAk0Bx6moGr1bPVFpH0EcBvADuHdqEvayk32KdTPqnxwx~Bw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90011439,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90011439/thumbnails/1.jpg","file_name":"17.IAJPS17082022.pdf","download_url":"https://www.academia.edu/attachments/90011439/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90011439/17.IAJPS17082022-libre.pdf?1661068504=\u0026response-content-disposition=attachment%3B+filename%3DCOMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf\u0026Expires=1732784476\u0026Signature=SB8KowC9GDnVABR1TiKgiOE0azvt~a1i2DrPNGiRKMHUc7C3lBLdceefol3AjJ3OA0frt8daaQyzaeA7BLwHRHUyZZYmttTGAg76mFn1C2ynRGXUyD4zFiS3ztPl2xhI3OzcNeidTVKef2HO3VKwkW2ycMxgccMieyL9jfKQ6WTdEA5dAYH6TgaZPl46LmMCmsKl3uI0s8HoRz3kA-EdlFVRZ~9~lp0bXzO8Us0B2K1Vlrfnnhu~1pvmE6ZIbE5eMIky1hq8C-mX~KD1BnIUI34W3krdZhnf0FFuX8qAk0Bx6moGr1bPVFpH0EcBvADuHdqEvayk32KdTPqnxwx~Bw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84990395"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84990395/FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION"><img alt="Research paper thumbnail of FLOATING MICROSPHERES ENCAPSULATING CARVEDILOL FOR EFFECTIVE MANAGEMENT OF HYPERTENSION" class="work-thumbnail" src="https://attachments.academia-assets.com/89829516/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84990395/FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION">FLOATING MICROSPHERES ENCAPSULATING CARVEDILOL FOR EFFECTIVE MANAGEMENT OF HYPERTENSION</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The objective of the present study was to formulate and evaluate floating microspheres of carvedi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The objective of the present study was to formulate and evaluate floating microspheres of carvedilol. Carvedilol has a terminal half-life of 7-10 hr, but most of the drug is eliminated with a half-life of about 2hr.Besidesbeingabeneficialdrugcomparedtoother drugs of the same class, it has narrow absorption window in upper part of the gastro intestinal tract, hence a floating drug delivery system is preferred, such that the formulation will be available for a longer duration than usual for absorption. Floating microspheres were prepared by emulsion solvent diffusion method using ethanol and dichloromethane as solvents. Ethyl cellulose and Hydroxy propyl methyl cellulose, HPMC K 4 M, were used to prolong the release of the drug from microspheres. The prepared microspheres were subjected to various evaluatory studies. All the microspheres were found to have a size in the range of 20-40 μ and were nearly spherical in shape. For optimization of Formulation F1 (EudragitRS100), F2 (Acrycoat S 100) and F3 (Cellulose Acetate) was selected.  The formulation F1 prepared using EudragitRS100 showed 82.5±2.76 percentage drug release AFTER 24 Hrs. as compare to other formulations.<br />Key words: Carvedilol, Floating microspheres, Hypertension</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f0db93f6adf85f8535de59ab5f4a1efb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89829516,"asset_id":84990395,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89829516/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84990395"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84990395"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84990395; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84990395]").text(description); $(".js-view-count[data-work-id=84990395]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84990395; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84990395']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84990395, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f0db93f6adf85f8535de59ab5f4a1efb" } } $('.js-work-strip[data-work-id=84990395]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84990395,"title":"FLOATING MICROSPHERES ENCAPSULATING CARVEDILOL FOR EFFECTIVE MANAGEMENT OF HYPERTENSION","translated_title":"","metadata":{"doi":"10.5281/zenodo.7004318","abstract":"The objective of the present study was to formulate and evaluate floating microspheres of carvedilol. Carvedilol has a terminal half-life of 7-10 hr, but most of the drug is eliminated with a half-life of about 2hr.Besidesbeingabeneficialdrugcomparedtoother drugs of the same class, it has narrow absorption window in upper part of the gastro intestinal tract, hence a floating drug delivery system is preferred, such that the formulation will be available for a longer duration than usual for absorption. Floating microspheres were prepared by emulsion solvent diffusion method using ethanol and dichloromethane as solvents. Ethyl cellulose and Hydroxy propyl methyl cellulose, HPMC K 4 M, were used to prolong the release of the drug from microspheres. The prepared microspheres were subjected to various evaluatory studies. All the microspheres were found to have a size in the range of 20-40 μ and were nearly spherical in shape. For optimization of Formulation F1 (EudragitRS100), F2 (Acrycoat S 100) and F3 (Cellulose Acetate) was selected. The formulation F1 prepared using EudragitRS100 showed 82.5±2.76 percentage drug release AFTER 24 Hrs. as compare to other formulations.\nKey words: Carvedilol, Floating microspheres, Hypertension\n"},"translated_abstract":"The objective of the present study was to formulate and evaluate floating microspheres of carvedilol. Carvedilol has a terminal half-life of 7-10 hr, but most of the drug is eliminated with a half-life of about 2hr.Besidesbeingabeneficialdrugcomparedtoother drugs of the same class, it has narrow absorption window in upper part of the gastro intestinal tract, hence a floating drug delivery system is preferred, such that the formulation will be available for a longer duration than usual for absorption. Floating microspheres were prepared by emulsion solvent diffusion method using ethanol and dichloromethane as solvents. Ethyl cellulose and Hydroxy propyl methyl cellulose, HPMC K 4 M, were used to prolong the release of the drug from microspheres. The prepared microspheres were subjected to various evaluatory studies. All the microspheres were found to have a size in the range of 20-40 μ and were nearly spherical in shape. For optimization of Formulation F1 (EudragitRS100), F2 (Acrycoat S 100) and F3 (Cellulose Acetate) was selected. The formulation F1 prepared using EudragitRS100 showed 82.5±2.76 percentage drug release AFTER 24 Hrs. as compare to other formulations.\nKey words: Carvedilol, Floating microspheres, Hypertension\n","internal_url":"https://www.academia.edu/84990395/FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION","translated_internal_url":"","created_at":"2022-08-17T09:10:16.853-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89829516,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829516/thumbnails/1.jpg","file_name":"16.IAJPS16082022.pdf","download_url":"https://www.academia.edu/attachments/89829516/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829516/16.IAJPS16082022-libre.pdf?1660754686=\u0026response-content-disposition=attachment%3B+filename%3DFLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf\u0026Expires=1732784476\u0026Signature=CbFVJ5fq6DDvjidAxZWQSLhwfe4s0PEXRdX-2CiCZmxr5iCpnbvPWspXvw5yuI5uHTvkvx3W8nJQ217FTw40J35p6f5BxAaKogtQ8eGkr1hTdeZyJ~9I1O1kHtc2oFmPPQp~NiWxSAzI6Swm2lKy0K~za0mKI8IsJhfll-LFElkUGWbNYrpydE29Y1-85WSLqba-b0Twkq6LQP9sufI2Ma6GC0UnwF9saqTlY3HFjIHiR30ZcU60pUy2PrxMaWroxeJCdWunT~eGqKPlPmEvNVAVl4XxDY7j-d0btOROUg~BctDhIt~oyCmBpcptyIEJ5DOLkTBs7jXJQPyAQ~iUEw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION","translated_slug":"","page_count":4,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89829516,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829516/thumbnails/1.jpg","file_name":"16.IAJPS16082022.pdf","download_url":"https://www.academia.edu/attachments/89829516/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829516/16.IAJPS16082022-libre.pdf?1660754686=\u0026response-content-disposition=attachment%3B+filename%3DFLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf\u0026Expires=1732784476\u0026Signature=CbFVJ5fq6DDvjidAxZWQSLhwfe4s0PEXRdX-2CiCZmxr5iCpnbvPWspXvw5yuI5uHTvkvx3W8nJQ217FTw40J35p6f5BxAaKogtQ8eGkr1hTdeZyJ~9I1O1kHtc2oFmPPQp~NiWxSAzI6Swm2lKy0K~za0mKI8IsJhfll-LFElkUGWbNYrpydE29Y1-85WSLqba-b0Twkq6LQP9sufI2Ma6GC0UnwF9saqTlY3HFjIHiR30ZcU60pUy2PrxMaWroxeJCdWunT~eGqKPlPmEvNVAVl4XxDY7j-d0btOROUg~BctDhIt~oyCmBpcptyIEJ5DOLkTBs7jXJQPyAQ~iUEw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84990215"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84990215/PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA"><img alt="Research paper thumbnail of PHYTOCHEMICAL SCREENING AND IN-VIVO ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF MORINGA OLEIFERA" class="work-thumbnail" src="https://attachments.academia-assets.com/89829350/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84990215/PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA">PHYTOCHEMICAL SCREENING AND IN-VIVO ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF MORINGA OLEIFERA</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarmi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. Moringa oleifera (M. oleifera) popularly known as miracle tree belongs to the family Moringaceae.  It  is  a  medicinal  plant  in  which  the  leaves  are  the  most  nutritious  part,  being  a  significant  source  of  vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. This study investigated the protective and ameliorative potential of ethanol extract of M. oleifera leaf (50-200mg/kg) on alloxan-induced diabetes in Wistar rats. Qualitative analysis of various phytochemical constituents was determined by the well-known test protocol available in the literature. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats. Glucose concentrations in extract, glibenclamide or metformin post-alloxan administered rats were decreased compared to diabetic rats. But they were higher than control, except by day 14 wherein glucose level was normal or lower. When compared with glibenclamide or metformin, glucose levels of extract treated animals were higher on the 7th day, but lower at the end of treatment. In addition, extract treatment caused hypoglycemia after fourteen days of treatment in normal rats. The results demonstrate that M. oleifera leaf possesses protective and ameliorative antidiabetic potential in rats.<br />Keywords: Diabetes mellitus, Moringa oleifera, Phytochemical screening, Alloxan monohydrate.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6e1be523c003786fd6262e3aefb732d6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89829350,"asset_id":84990215,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89829350/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84990215"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84990215"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84990215; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84990215]").text(description); $(".js-view-count[data-work-id=84990215]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84990215; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84990215']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84990215, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6e1be523c003786fd6262e3aefb732d6" } } $('.js-work-strip[data-work-id=84990215]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84990215,"title":"PHYTOCHEMICAL SCREENING AND IN-VIVO ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF MORINGA OLEIFERA","translated_title":"","metadata":{"doi":"10.5281/zenodo.7004288","abstract":"Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. Moringa oleifera (M. oleifera) popularly known as miracle tree belongs to the family Moringaceae. It is a medicinal plant in which the leaves are the most nutritious part, being a significant source of vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. This study investigated the protective and ameliorative potential of ethanol extract of M. oleifera leaf (50-200mg/kg) on alloxan-induced diabetes in Wistar rats. Qualitative analysis of various phytochemical constituents was determined by the well-known test protocol available in the literature. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats. Glucose concentrations in extract, glibenclamide or metformin post-alloxan administered rats were decreased compared to diabetic rats. But they were higher than control, except by day 14 wherein glucose level was normal or lower. When compared with glibenclamide or metformin, glucose levels of extract treated animals were higher on the 7th day, but lower at the end of treatment. In addition, extract treatment caused hypoglycemia after fourteen days of treatment in normal rats. The results demonstrate that M. oleifera leaf possesses protective and ameliorative antidiabetic potential in rats.\nKeywords: Diabetes mellitus, Moringa oleifera, Phytochemical screening, Alloxan monohydrate.\n"},"translated_abstract":"Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. Moringa oleifera (M. oleifera) popularly known as miracle tree belongs to the family Moringaceae. It is a medicinal plant in which the leaves are the most nutritious part, being a significant source of vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. This study investigated the protective and ameliorative potential of ethanol extract of M. oleifera leaf (50-200mg/kg) on alloxan-induced diabetes in Wistar rats. Qualitative analysis of various phytochemical constituents was determined by the well-known test protocol available in the literature. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats. Glucose concentrations in extract, glibenclamide or metformin post-alloxan administered rats were decreased compared to diabetic rats. But they were higher than control, except by day 14 wherein glucose level was normal or lower. When compared with glibenclamide or metformin, glucose levels of extract treated animals were higher on the 7th day, but lower at the end of treatment. In addition, extract treatment caused hypoglycemia after fourteen days of treatment in normal rats. The results demonstrate that M. oleifera leaf possesses protective and ameliorative antidiabetic potential in rats.\nKeywords: Diabetes mellitus, Moringa oleifera, Phytochemical screening, Alloxan monohydrate.\n","internal_url":"https://www.academia.edu/84990215/PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA","translated_internal_url":"","created_at":"2022-08-17T09:07:38.611-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89829350,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829350/thumbnails/1.jpg","file_name":"15.IAJPS15082022.pdf","download_url":"https://www.academia.edu/attachments/89829350/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829350/15.IAJPS15082022-libre.pdf?1660754687=\u0026response-content-disposition=attachment%3B+filename%3DPHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf\u0026Expires=1732810433\u0026Signature=IkauyKrUmDN1~3~zTm8HCdhoI1TzpCCEhWvQ6K2L5M6rLVm-iDugeKm-ooYCi~TPFtd9hcjc-6b36T5X4qEh5yscPYyNGcUcqjoPouwXzQStivHmTzcbXK6qm0oMt-K5UoE9uGFpYPwV59q0oHG1voWddHDjcc1ZvriHZAI6qyJ9QhhTfmSOTL7~nU8Vbr1ufiF8AZACoQPqV2JZGLaelqS4ecGMbPN~r6rRsg6M-AXbbazhb7jaIPvDy1nMgYyybDnkP6R~KYotAeesAx9Cha3Y8rT23Fo0Sh9T5FwAl-RrswfAWDb35NQz5ufXzWlCimq90zx9Rznc4Y9ZoyLjHQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"ZmtnM0d0L3IvaTFvVDhMb2JEYUZsYWZoWjVSMEl3OHh2dWRvdGlGaWFQN05maHdlb20vK0tib0owYlk0L2FRMC0tdHJPQVIvK1dmNnJvR2RvUytGN0VyUT09--0d85adcbbaf572910cfa71275da26fda1f66fee0"},"attachments":[{"id":89829350,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829350/thumbnails/1.jpg","file_name":"15.IAJPS15082022.pdf","download_url":"https://www.academia.edu/attachments/89829350/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829350/15.IAJPS15082022-libre.pdf?1660754687=\u0026response-content-disposition=attachment%3B+filename%3DPHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf\u0026Expires=1732810433\u0026Signature=IkauyKrUmDN1~3~zTm8HCdhoI1TzpCCEhWvQ6K2L5M6rLVm-iDugeKm-ooYCi~TPFtd9hcjc-6b36T5X4qEh5yscPYyNGcUcqjoPouwXzQStivHmTzcbXK6qm0oMt-K5UoE9uGFpYPwV59q0oHG1voWddHDjcc1ZvriHZAI6qyJ9QhhTfmSOTL7~nU8Vbr1ufiF8AZACoQPqV2JZGLaelqS4ecGMbPN~r6rRsg6M-AXbbazhb7jaIPvDy1nMgYyybDnkP6R~KYotAeesAx9Cha3Y8rT23Fo0Sh9T5FwAl-RrswfAWDb35NQz5ufXzWlCimq90zx9Rznc4Y9ZoyLjHQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84888529"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84888529/DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC"><img alt="Research paper thumbnail of DEVELOPMENT AND EVALUATION OF OSMOTIC PUMP TABLETS OF ACECLOFENAC" class="work-thumbnail" src="https://attachments.academia-assets.com/89760828/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84888529/DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC">DEVELOPMENT AND EVALUATION OF OSMOTIC PUMP TABLETS OF ACECLOFENAC</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The aim of the work is to develop & evaluate bilayer-core osmotic pump tablet by wet granulation ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The aim of the work is to develop & evaluate bilayer-core osmotic pump tablet by wet granulation method, using Aceclofenac as model drug. The prepared bilayer- core osmotic pump tablet will be evaluated for influence of sodium chloride, PEO (WSR Coagulant) and PEG level on drug release profile, etc. The granules of drug layer and push layer were prepared separately by wet granulation method using isopropyl alcohol. The prepared osmotic tablet of Aceclofenac was coated using ethyl cellulose as semi permeable membrane and PEG 400 as pore forming agent, the prepared tablets were evaluated for bulk density, tapped density, compressibility index, angle of repose, weight variation test, hardness, friability, content uniformity and In vitro drug release studied using USP XXIX Paddle method; formulated tablets were also evaluated for effect of pH, effect of agitation, FTIR, the results of IR study showed that there is no interaction between osmo agent, and pure drug. <br />Results showed that as the concentration of the sodium chloride and PEO (WSR Coagulant) increases it affects the in vitro drug release. Formulation F6 prepared with sodium chloride 65mg, PEO (WSR Coagulant) 37.5mg which exhibited excellent micro meritic properties, percentage yield, and percentage drug release 84.089 % for a period of 12 hrs.Osmotic tablets of Aceclofenac may be an effective alternative to conventional dosage form, which can be effectively used in the treatment of Rheumatoid arthritis. <br />Keywords:  Osmogent, Osmotic pump tablets, Aceclofenac, disintegration time.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ee4afcfdaa1f093b39a0cb556b7379f5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89760828,"asset_id":84888529,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89760828/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84888529"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84888529"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84888529; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84888529]").text(description); $(".js-view-count[data-work-id=84888529]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84888529; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84888529']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84888529, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ee4afcfdaa1f093b39a0cb556b7379f5" } } $('.js-work-strip[data-work-id=84888529]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84888529,"title":"DEVELOPMENT AND EVALUATION OF OSMOTIC PUMP TABLETS OF ACECLOFENAC","translated_title":"","metadata":{"doi":"10.5281/zenodo.6998101","abstract":"The aim of the work is to develop \u0026 evaluate bilayer-core osmotic pump tablet by wet granulation method, using Aceclofenac as model drug. The prepared bilayer- core osmotic pump tablet will be evaluated for influence of sodium chloride, PEO (WSR Coagulant) and PEG level on drug release profile, etc. The granules of drug layer and push layer were prepared separately by wet granulation method using isopropyl alcohol. The prepared osmotic tablet of Aceclofenac was coated using ethyl cellulose as semi permeable membrane and PEG 400 as pore forming agent, the prepared tablets were evaluated for bulk density, tapped density, compressibility index, angle of repose, weight variation test, hardness, friability, content uniformity and In vitro drug release studied using USP XXIX Paddle method; formulated tablets were also evaluated for effect of pH, effect of agitation, FTIR, the results of IR study showed that there is no interaction between osmo agent, and pure drug. \nResults showed that as the concentration of the sodium chloride and PEO (WSR Coagulant) increases it affects the in vitro drug release. Formulation F6 prepared with sodium chloride 65mg, PEO (WSR Coagulant) 37.5mg which exhibited excellent micro meritic properties, percentage yield, and percentage drug release 84.089 % for a period of 12 hrs.Osmotic tablets of Aceclofenac may be an effective alternative to conventional dosage form, which can be effectively used in the treatment of Rheumatoid arthritis. \nKeywords: Osmogent, Osmotic pump tablets, Aceclofenac, disintegration time.\n"},"translated_abstract":"The aim of the work is to develop \u0026 evaluate bilayer-core osmotic pump tablet by wet granulation method, using Aceclofenac as model drug. The prepared bilayer- core osmotic pump tablet will be evaluated for influence of sodium chloride, PEO (WSR Coagulant) and PEG level on drug release profile, etc. The granules of drug layer and push layer were prepared separately by wet granulation method using isopropyl alcohol. The prepared osmotic tablet of Aceclofenac was coated using ethyl cellulose as semi permeable membrane and PEG 400 as pore forming agent, the prepared tablets were evaluated for bulk density, tapped density, compressibility index, angle of repose, weight variation test, hardness, friability, content uniformity and In vitro drug release studied using USP XXIX Paddle method; formulated tablets were also evaluated for effect of pH, effect of agitation, FTIR, the results of IR study showed that there is no interaction between osmo agent, and pure drug. \nResults showed that as the concentration of the sodium chloride and PEO (WSR Coagulant) increases it affects the in vitro drug release. Formulation F6 prepared with sodium chloride 65mg, PEO (WSR Coagulant) 37.5mg which exhibited excellent micro meritic properties, percentage yield, and percentage drug release 84.089 % for a period of 12 hrs.Osmotic tablets of Aceclofenac may be an effective alternative to conventional dosage form, which can be effectively used in the treatment of Rheumatoid arthritis. \nKeywords: Osmogent, Osmotic pump tablets, Aceclofenac, disintegration time.\n","internal_url":"https://www.academia.edu/84888529/DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC","translated_internal_url":"","created_at":"2022-08-16T06:40:17.014-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89760828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89760828/thumbnails/1.jpg","file_name":"14.IAJPS14082022.pdf","download_url":"https://www.academia.edu/attachments/89760828/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89760828/14.IAJPS14082022-libre.pdf?1660658204=\u0026response-content-disposition=attachment%3B+filename%3DDEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf\u0026Expires=1732632476\u0026Signature=WMkGeacUCnyrsFWkA9Vqxd2VLJ0wi5j6PNYWrtCfKR4COEvTkP1HW6L5Zj1rQhxK-zBuxSYDf0PFJfxB1iWZft0P9e7g8kPm5uM9FTsTZhB5kQIWuyM5N-cQRjNjWEIeqFvqYQ~ikqUjWxAL7h9jG~M1csPITTy30RcobbtQyuk-T-2wxkgdu0C3JtWgcN-Dgo-SxXMixiRlHFRyViDvh5uTDPXogxwSTtJwgFl9Ki8O16pTNNiT3N2VKntWZAdVIxa4zGvVD1lvmy7QveVZuR5jdZGz0pwDKl39i2KquHlA7l-hCzD3oJNw7FOgcZzlWg9gnfJVSAy7Wc0Qn4xA5Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC","translated_slug":"","page_count":19,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89760828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89760828/thumbnails/1.jpg","file_name":"14.IAJPS14082022.pdf","download_url":"https://www.academia.edu/attachments/89760828/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89760828/14.IAJPS14082022-libre.pdf?1660658204=\u0026response-content-disposition=attachment%3B+filename%3DDEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf\u0026Expires=1732632476\u0026Signature=WMkGeacUCnyrsFWkA9Vqxd2VLJ0wi5j6PNYWrtCfKR4COEvTkP1HW6L5Zj1rQhxK-zBuxSYDf0PFJfxB1iWZft0P9e7g8kPm5uM9FTsTZhB5kQIWuyM5N-cQRjNjWEIeqFvqYQ~ikqUjWxAL7h9jG~M1csPITTy30RcobbtQyuk-T-2wxkgdu0C3JtWgcN-Dgo-SxXMixiRlHFRyViDvh5uTDPXogxwSTtJwgFl9Ki8O16pTNNiT3N2VKntWZAdVIxa4zGvVD1lvmy7QveVZuR5jdZGz0pwDKl39i2KquHlA7l-hCzD3oJNw7FOgcZzlWg9gnfJVSAy7Wc0Qn4xA5Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84557260"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84557260/ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER"><img alt="Research paper thumbnail of ANTI-TUMOR ACTIVITY OF MERCAPTOPURINE IN COMBINATION WITH PEPPER" class="work-thumbnail" src="https://attachments.academia-assets.com/89538157/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84557260/ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER">ANTI-TUMOR ACTIVITY OF MERCAPTOPURINE IN COMBINATION WITH PEPPER</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Cancer is one of the most life-threatening diseases and serious health problem in both developing...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Cancer is one of the most life-threatening diseases and serious health problem in both developing and developed countries. Many synthetic and chemotherapeutic agents used in cancer therapy are having low bioavailability and involve the risk of life-threatening host toxicity. Modern researchers are increasingly showing interest toward the improvement of bioavailability of a large number of drugs by addition of various herbs with bioenhancing properties. In oral drug delivery system, the co-administration of therapeutic agents with natural compounds possessing absorption improving activities, has also garnered great interest. Hence the present study was conducted to evaluate the anti-tumor activity of Mercaptopurine in combination with pepper extract. 20- Methylcholanthrene a Polycyclic aromatic hydrocarbons was used to induce tumor in albino mice. Haematological and endogenous antioxidant parameters were evaluated in the study. Treatment with Mercaptopurine and in combination with pepper extract significantly restored the altered haematological and antioxidant parameters to normal values. <br />Key words: cancer, bioenhancer, pepper, tumor, Haemoglobin, Lipid peroxidation.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d7f66e3cf0348076e8cf1b9d9fc4969e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89538157,"asset_id":84557260,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89538157/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84557260"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84557260"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84557260; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84557260]").text(description); $(".js-view-count[data-work-id=84557260]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84557260; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84557260']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84557260, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "d7f66e3cf0348076e8cf1b9d9fc4969e" } } $('.js-work-strip[data-work-id=84557260]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84557260,"title":"ANTI-TUMOR ACTIVITY OF MERCAPTOPURINE IN COMBINATION WITH PEPPER","translated_title":"","metadata":{"doi":"10.5281/zenodo.6985560","abstract":"Cancer is one of the most life-threatening diseases and serious health problem in both developing and developed countries. Many synthetic and chemotherapeutic agents used in cancer therapy are having low bioavailability and involve the risk of life-threatening host toxicity. Modern researchers are increasingly showing interest toward the improvement of bioavailability of a large number of drugs by addition of various herbs with bioenhancing properties. In oral drug delivery system, the co-administration of therapeutic agents with natural compounds possessing absorption improving activities, has also garnered great interest. Hence the present study was conducted to evaluate the anti-tumor activity of Mercaptopurine in combination with pepper extract. 20- Methylcholanthrene a Polycyclic aromatic hydrocarbons was used to induce tumor in albino mice. Haematological and endogenous antioxidant parameters were evaluated in the study. Treatment with Mercaptopurine and in combination with pepper extract significantly restored the altered haematological and antioxidant parameters to normal values. \nKey words: cancer, bioenhancer, pepper, tumor, Haemoglobin, Lipid peroxidation.\n"},"translated_abstract":"Cancer is one of the most life-threatening diseases and serious health problem in both developing and developed countries. Many synthetic and chemotherapeutic agents used in cancer therapy are having low bioavailability and involve the risk of life-threatening host toxicity. Modern researchers are increasingly showing interest toward the improvement of bioavailability of a large number of drugs by addition of various herbs with bioenhancing properties. In oral drug delivery system, the co-administration of therapeutic agents with natural compounds possessing absorption improving activities, has also garnered great interest. Hence the present study was conducted to evaluate the anti-tumor activity of Mercaptopurine in combination with pepper extract. 20- Methylcholanthrene a Polycyclic aromatic hydrocarbons was used to induce tumor in albino mice. Haematological and endogenous antioxidant parameters were evaluated in the study. Treatment with Mercaptopurine and in combination with pepper extract significantly restored the altered haematological and antioxidant parameters to normal values. \nKey words: cancer, bioenhancer, pepper, tumor, Haemoglobin, Lipid peroxidation.\n","internal_url":"https://www.academia.edu/84557260/ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER","translated_internal_url":"","created_at":"2022-08-12T08:55:30.319-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89538157,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89538157/thumbnails/1.jpg","file_name":"13.IAJPS13082022.pdf","download_url":"https://www.academia.edu/attachments/89538157/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89538157/13.IAJPS13082022-libre.pdf?1660322008=\u0026response-content-disposition=attachment%3B+filename%3DANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf\u0026Expires=1732719333\u0026Signature=IU~XpADY-zxuc6cuO2Ez22vgwlCWNcmoSFLQfsK9ORmwQtmfo2PoS5P43ZCTZXnWczfh3iuE7waEky-0Jogez7mRgFyRuD27HJWO0u7zoTNPmEgFFR62~rUloY2otWBgvnxrgEl0oDVMkozZmIYnqJSVYRz4wTFMNl19w4UNgSRThjVpP2svpb6Pgwy~ZyzXW7fZUpNTNJ7gV0d1B0sI5hQlPrTObpBejbo4MHBmw7zlSMH95M-VN673EXUDzWBEpArsqRnASIUzE5OI9~uOOB4w0KTzI3tn6yIGwuyET5tGJOo90r8RXInXeEMQNZeQmM9RgqYqphsZFhFUhaLrKw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89538157,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89538157/thumbnails/1.jpg","file_name":"13.IAJPS13082022.pdf","download_url":"https://www.academia.edu/attachments/89538157/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89538157/13.IAJPS13082022-libre.pdf?1660322008=\u0026response-content-disposition=attachment%3B+filename%3DANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf\u0026Expires=1732719333\u0026Signature=IU~XpADY-zxuc6cuO2Ez22vgwlCWNcmoSFLQfsK9ORmwQtmfo2PoS5P43ZCTZXnWczfh3iuE7waEky-0Jogez7mRgFyRuD27HJWO0u7zoTNPmEgFFR62~rUloY2otWBgvnxrgEl0oDVMkozZmIYnqJSVYRz4wTFMNl19w4UNgSRThjVpP2svpb6Pgwy~ZyzXW7fZUpNTNJ7gV0d1B0sI5hQlPrTObpBejbo4MHBmw7zlSMH95M-VN673EXUDzWBEpArsqRnASIUzE5OI9~uOOB4w0KTzI3tn6yIGwuyET5tGJOo90r8RXInXeEMQNZeQmM9RgqYqphsZFhFUhaLrKw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84491430"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84491430/QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER"><img alt="Research paper thumbnail of QUANTITATIVE EVALUATION OF N-NITROSAMINE IMPURITIES IN TELMISARTAN TABLETS USP 20MG, 40MG AND 80MG BY GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETER" class="work-thumbnail" src="https://attachments.academia-assets.com/89496395/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84491430/QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER">QUANTITATIVE EVALUATION OF N-NITROSAMINE IMPURITIES IN TELMISARTAN TABLETS USP 20MG, 40MG AND 80MG BY GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETER</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitroso...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitrosodiisopropylamine, N-Nitrosoisopropylethylamine, N-Nitrosodibutylamine) in Telmisartan Tablets USP 20 mg, 40 mg and 80 mg by GC-MS/MS. Using column Rtx-5 Amine fused silica capillary column with Base deactivated guard column. The validation of optimized method was carried out in accordance with relevant validation principles. The authenticated procedure was noticed to be specific, precise, linear, accurate and rugged with concentration ranging from limit of quantification (LOQ) to 200% specification level for Nitrosamine Impurities. As per daily dose of Telmisartan Tablets, the specification limits of N-Nitrosodimethylamine is 1.2mcg/gm and other Nitrosamine Impurities is 0.33mcg/gm. In this method the limit of detection for N-Nitrosodimethylamine is 0.12mcg/gm and other Nitrosamine Impurities is 0.033mcg/gm. The established method was productively useful to determine the N-Nitrosamine Impurities in Telmisartan Tablets.<br />Keywords: Gas chromatography coupled with mass spectrometry (GC-MS/MS), Telmisartan tablets USP, Nitrosamine impurities, ICH guideline.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="cac53d0408077fb3a8938823c3a2c880" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89496395,"asset_id":84491430,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89496395/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84491430"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84491430"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84491430; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84491430]").text(description); $(".js-view-count[data-work-id=84491430]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84491430; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84491430']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84491430, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "cac53d0408077fb3a8938823c3a2c880" } } $('.js-work-strip[data-work-id=84491430]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84491430,"title":"QUANTITATIVE EVALUATION OF N-NITROSAMINE IMPURITIES IN TELMISARTAN TABLETS USP 20MG, 40MG AND 80MG BY GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETER","translated_title":"","metadata":{"doi":"10.5281/zenodo.6983632","abstract":"Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitrosodiisopropylamine, N-Nitrosoisopropylethylamine, N-Nitrosodibutylamine) in Telmisartan Tablets USP 20 mg, 40 mg and 80 mg by GC-MS/MS. Using column Rtx-5 Amine fused silica capillary column with Base deactivated guard column. The validation of optimized method was carried out in accordance with relevant validation principles. The authenticated procedure was noticed to be specific, precise, linear, accurate and rugged with concentration ranging from limit of quantification (LOQ) to 200% specification level for Nitrosamine Impurities. As per daily dose of Telmisartan Tablets, the specification limits of N-Nitrosodimethylamine is 1.2mcg/gm and other Nitrosamine Impurities is 0.33mcg/gm. In this method the limit of detection for N-Nitrosodimethylamine is 0.12mcg/gm and other Nitrosamine Impurities is 0.033mcg/gm. The established method was productively useful to determine the N-Nitrosamine Impurities in Telmisartan Tablets.\nKeywords: Gas chromatography coupled with mass spectrometry (GC-MS/MS), Telmisartan tablets USP, Nitrosamine impurities, ICH guideline.\n"},"translated_abstract":"Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitrosodiisopropylamine, N-Nitrosoisopropylethylamine, N-Nitrosodibutylamine) in Telmisartan Tablets USP 20 mg, 40 mg and 80 mg by GC-MS/MS. Using column Rtx-5 Amine fused silica capillary column with Base deactivated guard column. The validation of optimized method was carried out in accordance with relevant validation principles. The authenticated procedure was noticed to be specific, precise, linear, accurate and rugged with concentration ranging from limit of quantification (LOQ) to 200% specification level for Nitrosamine Impurities. As per daily dose of Telmisartan Tablets, the specification limits of N-Nitrosodimethylamine is 1.2mcg/gm and other Nitrosamine Impurities is 0.33mcg/gm. In this method the limit of detection for N-Nitrosodimethylamine is 0.12mcg/gm and other Nitrosamine Impurities is 0.033mcg/gm. The established method was productively useful to determine the N-Nitrosamine Impurities in Telmisartan Tablets.\nKeywords: Gas chromatography coupled with mass spectrometry (GC-MS/MS), Telmisartan tablets USP, Nitrosamine impurities, ICH guideline.\n","internal_url":"https://www.academia.edu/84491430/QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER","translated_internal_url":"","created_at":"2022-08-11T11:43:35.249-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89496395,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496395/thumbnails/1.jpg","file_name":"12.IAJPS12082022.pdf","download_url":"https://www.academia.edu/attachments/89496395/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496395/12.IAJPS12082022-libre.pdf?1660254587=\u0026response-content-disposition=attachment%3B+filename%3DQUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf\u0026Expires=1732810433\u0026Signature=OJxKSsmaOausOFT3so8yaFRscsPWn3zqWks2n2C5znY8XkqjdPRwsxHVwXT8TRunAaMyWtFO~w8v7CMkjYtrXW~PmedGrqC7TKMguzWmNB9KIuR-hw9B9wBDZOXnk5vK~qM7oQZ1pl2nDNc2kqL79DOcmyX8Jdba3AUGV251EnEiF9QeR9kSvS2Dc4QkKy8p7Ph3Qz4vDTo3IK9MBFQ87rFBP7EqrYA37vE6XnvT7wUpIJOnAUa9Uq-dXgV00ng-3sBuH0hJTY6n-Kk-iSwVrk06gHt6jWbgLygQb7rT93-g4MZsiAr2w4LXvFygi6BMaTRj6NzoZv68Y4FtfsqIHg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER","translated_slug":"","page_count":17,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"Ui9sMjQ3QkNjOVJOZlpVRmRkQWtnMXZneWZuKytHb3UvYTZ4cVlZTGd0MjFLSXpUZEN6MzVnWHN5bjBZMWtDNC0tWXFUZ2VJZkVsRFJyUE5idTlrYndXUT09--c936f20b4ea3b7da38d39058f4fbbcd44511d9ef"},"attachments":[{"id":89496395,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496395/thumbnails/1.jpg","file_name":"12.IAJPS12082022.pdf","download_url":"https://www.academia.edu/attachments/89496395/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496395/12.IAJPS12082022-libre.pdf?1660254587=\u0026response-content-disposition=attachment%3B+filename%3DQUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf\u0026Expires=1732810433\u0026Signature=OJxKSsmaOausOFT3so8yaFRscsPWn3zqWks2n2C5znY8XkqjdPRwsxHVwXT8TRunAaMyWtFO~w8v7CMkjYtrXW~PmedGrqC7TKMguzWmNB9KIuR-hw9B9wBDZOXnk5vK~qM7oQZ1pl2nDNc2kqL79DOcmyX8Jdba3AUGV251EnEiF9QeR9kSvS2Dc4QkKy8p7Ph3Qz4vDTo3IK9MBFQ87rFBP7EqrYA37vE6XnvT7wUpIJOnAUa9Uq-dXgV00ng-3sBuH0hJTY6n-Kk-iSwVrk06gHt6jWbgLygQb7rT93-g4MZsiAr2w4LXvFygi6BMaTRj6NzoZv68Y4FtfsqIHg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84491285"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84491285/FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS"><img alt="Research paper thumbnail of FRAILTY IS A GOOD INDICATOR OF LENGTH OF HOSPITAL STAY IN PATIENTS SUFFERING FROM BACTERIAL MENINGITIS" class="work-thumbnail" src="https://attachments.academia-assets.com/89496343/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84491285/FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS">FRAILTY IS A GOOD INDICATOR OF LENGTH OF HOSPITAL STAY IN PATIENTS SUFFERING FROM BACTERIAL MENINGITIS</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Purpose: The purpose of the study is to analyze the effect of frailty index on the length of hos...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Purpose:  The purpose of the study is to analyze the effect of frailty index on the length of hospital stay.<br />Method:  After approval from Hospital Ethical committee data was taken from the previous records (hospital database) of patients who were admitted to Leady Reading Hospital, Peshawar for bacterial meningitis. The data was extracted from 2018 to 2021. SPSS 20 version was used for the data analysis.<br />Results:  Among 204 (62.2%) less frail patients, 188 patients (92.15%) had a hospital stay of 0-7 days and 16 patients (7.84%) had a hospital stay of 8-14 days. While in 124 severely frail patients(37.8%), 11 patients (8.9%) had a hospital stay of 0-7 days, 106 patients (85.5%) had a hospital stay of 8-14 days and 7 patients (5.6%) had a stay of greater than 14 days.<br />Conclusion:  We found that severely frail patients (mFI ≥3) had longer hospital stay compared to less frail patient (mFI≤2). This study demonstrated that frailty, not the age, is the independent indicator of poor clinical outcomes and length of hospital stay.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bcd2fcbc1d230c8faeb2a6158f249d14" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89496343,"asset_id":84491285,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89496343/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84491285"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84491285"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84491285; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84491285]").text(description); $(".js-view-count[data-work-id=84491285]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84491285; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84491285']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84491285, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bcd2fcbc1d230c8faeb2a6158f249d14" } } $('.js-work-strip[data-work-id=84491285]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84491285,"title":"FRAILTY IS A GOOD INDICATOR OF LENGTH OF HOSPITAL STAY IN PATIENTS SUFFERING FROM BACTERIAL MENINGITIS","translated_title":"","metadata":{"doi":"10.5281/zenodo.6983618","abstract":"Purpose: The purpose of the study is to analyze the effect of frailty index on the length of hospital stay.\nMethod: After approval from Hospital Ethical committee data was taken from the previous records (hospital database) of patients who were admitted to Leady Reading Hospital, Peshawar for bacterial meningitis. The data was extracted from 2018 to 2021. SPSS 20 version was used for the data analysis.\nResults: Among 204 (62.2%) less frail patients, 188 patients (92.15%) had a hospital stay of 0-7 days and 16 patients (7.84%) had a hospital stay of 8-14 days. While in 124 severely frail patients(37.8%), 11 patients (8.9%) had a hospital stay of 0-7 days, 106 patients (85.5%) had a hospital stay of 8-14 days and 7 patients (5.6%) had a stay of greater than 14 days.\nConclusion: We found that severely frail patients (mFI ≥3) had longer hospital stay compared to less frail patient (mFI≤2). This study demonstrated that frailty, not the age, is the independent indicator of poor clinical outcomes and length of hospital stay.\n"},"translated_abstract":"Purpose: The purpose of the study is to analyze the effect of frailty index on the length of hospital stay.\nMethod: After approval from Hospital Ethical committee data was taken from the previous records (hospital database) of patients who were admitted to Leady Reading Hospital, Peshawar for bacterial meningitis. The data was extracted from 2018 to 2021. SPSS 20 version was used for the data analysis.\nResults: Among 204 (62.2%) less frail patients, 188 patients (92.15%) had a hospital stay of 0-7 days and 16 patients (7.84%) had a hospital stay of 8-14 days. While in 124 severely frail patients(37.8%), 11 patients (8.9%) had a hospital stay of 0-7 days, 106 patients (85.5%) had a hospital stay of 8-14 days and 7 patients (5.6%) had a stay of greater than 14 days.\nConclusion: We found that severely frail patients (mFI ≥3) had longer hospital stay compared to less frail patient (mFI≤2). This study demonstrated that frailty, not the age, is the independent indicator of poor clinical outcomes and length of hospital stay.\n","internal_url":"https://www.academia.edu/84491285/FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS","translated_internal_url":"","created_at":"2022-08-11T11:41:20.043-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89496343,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496343/thumbnails/1.jpg","file_name":"11.IAJPS11082022.pdf","download_url":"https://www.academia.edu/attachments/89496343/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496343/11.IAJPS11082022-libre.pdf?1660254582=\u0026response-content-disposition=attachment%3B+filename%3DFRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf\u0026Expires=1732719333\u0026Signature=IveaHWrUp2l9TyJfwO9WnTM3s0HYULqvzjr5PI3RyxXb~l~pixqf6~Xfa9vgXFxgTEfhUBTTlIHXpUN2gGzwpu1UsIRMF2FZ9ZWIWQjpLpGuZRup52holKLxDyB9h94rEnbBxNcMq-x5u~QnoVf1jBpixDNLzRA4O3LLE1GeM7GCNNKGHJGAXqDI9ZQp2J40oNv~dP~01JDSRSmKj02WWWb1nfnFCnr8z0JR9BWK8cMmDxFQ5xMk5yTebabaLUq~9Rjqxo-40P2P~HFfLk7uXuaTGBJOxbxjBBlf--jXJ3I2P2~omVaAxdszgbY8Ty53ra6EJFON~xSGUOwcXNfiLA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89496343,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496343/thumbnails/1.jpg","file_name":"11.IAJPS11082022.pdf","download_url":"https://www.academia.edu/attachments/89496343/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496343/11.IAJPS11082022-libre.pdf?1660254582=\u0026response-content-disposition=attachment%3B+filename%3DFRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf\u0026Expires=1732719333\u0026Signature=IveaHWrUp2l9TyJfwO9WnTM3s0HYULqvzjr5PI3RyxXb~l~pixqf6~Xfa9vgXFxgTEfhUBTTlIHXpUN2gGzwpu1UsIRMF2FZ9ZWIWQjpLpGuZRup52holKLxDyB9h94rEnbBxNcMq-x5u~QnoVf1jBpixDNLzRA4O3LLE1GeM7GCNNKGHJGAXqDI9ZQp2J40oNv~dP~01JDSRSmKj02WWWb1nfnFCnr8z0JR9BWK8cMmDxFQ5xMk5yTebabaLUq~9Rjqxo-40P2P~HFfLk7uXuaTGBJOxbxjBBlf--jXJ3I2P2~omVaAxdszgbY8Ty53ra6EJFON~xSGUOwcXNfiLA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="1723210" id="papers"><div class="js-work-strip profile--work_container" data-work-id="96868605"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96868605/Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC"><img alt="Research paper thumbnail of Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96868605/Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC">Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://cvr.academia.edu/RaviPulla">Ravi Pulla</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://nagajunauniversity.academia.edu/Editoriajps">Editor iajps</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron Hydrochloride (AST) in tablet dosage forms. Waters Spherisorb ® 5μm CN, 250x4.6 mm, column with 5 μm particle size and the Mobile Phase consisting of 0.01M Ammonium Acetate in water adjusting the pH-3.2 with Methanol & Tetra Hydro Furan in ratio of 700:240:60 v/v & mobile phase used as a diluent in the gradient mode. The flow rate was 1.0 ml/min and the effluents were monitored at 295 nm. The retention time was 11.570 min and the detector response was linear in the concentration range of 56.1673.2 μg/mL for AST successively. The respective linear regression equation being Y= 27228.755x + 221036.4041 for AST. The Limit of Detection (LOD) & The Limit of Quantification (LOQ) was found to be 0.1 & 0.3 μg/mL for AST. The percentage assay of AST was 99.93%. The method was validated by determining its accuracy, precision and system suitability. The results of the study showed that the proposed...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96868605"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96868605"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96868605; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96868605]").text(description); $(".js-view-count[data-work-id=96868605]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96868605; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96868605']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96868605, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=96868605]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96868605,"title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC","translated_title":"","metadata":{"abstract":"A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron Hydrochloride (AST) in tablet dosage forms. Waters Spherisorb ® 5μm CN, 250x4.6 mm, column with 5 μm particle size and the Mobile Phase consisting of 0.01M Ammonium Acetate in water adjusting the pH-3.2 with Methanol \u0026 Tetra Hydro Furan in ratio of 700:240:60 v/v \u0026 mobile phase used as a diluent in the gradient mode. The flow rate was 1.0 ml/min and the effluents were monitored at 295 nm. The retention time was 11.570 min and the detector response was linear in the concentration range of 56.1673.2 μg/mL for AST successively. The respective linear regression equation being Y= 27228.755x + 221036.4041 for AST. The Limit of Detection (LOD) \u0026 The Limit of Quantification (LOQ) was found to be 0.1 \u0026 0.3 μg/mL for AST. The percentage assay of AST was 99.93%. The method was validated by determining its accuracy, precision and system suitability. The results of the study showed that the proposed...","publication_date":{"day":null,"month":null,"year":2014,"errors":{}}},"translated_abstract":"A simple, precise, rapid and accurate RPHPLC method was developed for the estimation of Alosetron Hydrochloride (AST) in tablet dosage forms. Waters Spherisorb ® 5μm CN, 250x4.6 mm, column with 5 μm particle size and the Mobile Phase consisting of 0.01M Ammonium Acetate in water adjusting the pH-3.2 with Methanol \u0026 Tetra Hydro Furan in ratio of 700:240:60 v/v \u0026 mobile phase used as a diluent in the gradient mode. The flow rate was 1.0 ml/min and the effluents were monitored at 295 nm. The retention time was 11.570 min and the detector response was linear in the concentration range of 56.1673.2 μg/mL for AST successively. The respective linear regression equation being Y= 27228.755x + 221036.4041 for AST. The Limit of Detection (LOD) \u0026 The Limit of Quantification (LOQ) was found to be 0.1 \u0026 0.3 μg/mL for AST. The percentage assay of AST was 99.93%. The method was validated by determining its accuracy, precision and system suitability. The results of the study showed that the proposed...","internal_url":"https://www.academia.edu/96868605/Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC","translated_internal_url":"","created_at":"2023-02-13T23:08:56.338-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":48709433,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":40970087,"work_id":96868605,"tagging_user_id":48709433,"tagged_user_id":289144415,"co_author_invite_id":null,"email":"a***n@gmail.com","display_order":0,"name":"asadulla khan","title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC"},{"id":40970088,"work_id":96868605,"tagging_user_id":48709433,"tagged_user_id":33192926,"co_author_invite_id":null,"email":"s***4@gmail.com","display_order":1073741824,"name":"Sorabh Agrawal","title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC"},{"id":40970089,"work_id":96868605,"tagging_user_id":48709433,"tagged_user_id":15402473,"co_author_invite_id":null,"email":"i***r@gmail.com","affiliation":"ANU-NARGANAJUNA","display_order":1610612736,"name":"Editor iajps","title":"Estimation of Alosetron Hydrochloride in Tablet Dosage Form by RP-HPLC"}],"downloadable_attachments":[],"slug":"Estimation_of_Alosetron_Hydrochloride_in_Tablet_Dosage_Form_by_RP_HPLC","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":48709433,"first_name":"Ravi","middle_initials":null,"last_name":"Pulla","page_name":"RaviPulla","domain_name":"cvr","created_at":"2016-05-14T06:13:18.288-07:00","display_name":"Ravi Pulla","url":"https://cvr.academia.edu/RaviPulla","email":"eEE3UXZjQ25OQ040Q0xIV0krMHZROTVkd3FBdzZCcGdUdUptVDJ5dGtPb0NSaFhWT1JSVzVtb2VPRmtxd3IyNy0taFVuVk9JdldlcnZOa1J3eGpPL0srZz09--d7e3fca9c2997c6436929093b60f33019927beea"},"attachments":[],"research_interests":[{"id":36149,"name":"Pharmaceutical Analysis","url":"https://www.academia.edu/Documents/in/Pharmaceutical_Analysis"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="106479377"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/106479377/A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review"><img alt="Research paper thumbnail of A Study Of The Factors Affecting The Growing Presence Of Girls In Iranian Universities For Continuing Their Higher Education: A Review" class="work-thumbnail" src="https://attachments.academia-assets.com/105665679/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/106479377/A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review">A Study Of The Factors Affecting The Growing Presence Of Girls In Iranian Universities For Continuing Their Higher Education: A Review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: Since during the few past decades we have been witness to the unprecedented increas...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: Since during the few past decades we have been witness to the unprecedented increase in the presence of girls in Iranian universities for continuing their higher education, the current study seeks to study this issue through literature review. Materials and Methods: This study has been conducted in the form of a simple literature review. Research data are collected via searching the published papers in trusted Iranian and Foreign websites based on the following key words &quot;girls, continuing education, university and Iran&quot;. Findings: Generally speaking, the factors affecting the increase of the presence of girls in Iranian universities for continuing their education can be sought for in the following elements: economic motives (getting a job, acquiring financial independence, skill and economic vision acquisition), political motives (further participation in political affairs, having the ability to comment upon political affairs, acquiring vital and sensitive p...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b4a939da69b1ae64b5b1e031dd79038f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105665679,"asset_id":106479377,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105665679/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="106479377"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="106479377"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 106479377; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=106479377]").text(description); $(".js-view-count[data-work-id=106479377]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 106479377; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='106479377']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 106479377, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b4a939da69b1ae64b5b1e031dd79038f" } } $('.js-work-strip[data-work-id=106479377]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":106479377,"title":"A Study Of The Factors Affecting The Growing Presence Of Girls In Iranian Universities For Continuing Their Higher Education: A Review","translated_title":"","metadata":{"abstract":"Introduction: Since during the few past decades we have been witness to the unprecedented increase in the presence of girls in Iranian universities for continuing their higher education, the current study seeks to study this issue through literature review. Materials and Methods: This study has been conducted in the form of a simple literature review. Research data are collected via searching the published papers in trusted Iranian and Foreign websites based on the following key words \u0026quot;girls, continuing education, university and Iran\u0026quot;. Findings: Generally speaking, the factors affecting the increase of the presence of girls in Iranian universities for continuing their education can be sought for in the following elements: economic motives (getting a job, acquiring financial independence, skill and economic vision acquisition), political motives (further participation in political affairs, having the ability to comment upon political affairs, acquiring vital and sensitive p...","publisher":"Zenodo","publication_date":{"day":4,"month":2,"year":2018,"errors":{}}},"translated_abstract":"Introduction: Since during the few past decades we have been witness to the unprecedented increase in the presence of girls in Iranian universities for continuing their higher education, the current study seeks to study this issue through literature review. Materials and Methods: This study has been conducted in the form of a simple literature review. Research data are collected via searching the published papers in trusted Iranian and Foreign websites based on the following key words \u0026quot;girls, continuing education, university and Iran\u0026quot;. Findings: Generally speaking, the factors affecting the increase of the presence of girls in Iranian universities for continuing their education can be sought for in the following elements: economic motives (getting a job, acquiring financial independence, skill and economic vision acquisition), political motives (further participation in political affairs, having the ability to comment upon political affairs, acquiring vital and sensitive p...","internal_url":"https://www.academia.edu/106479377/A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review","translated_internal_url":"","created_at":"2023-09-11T07:14:28.164-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105665679,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665679/thumbnails/1.jpg","file_name":"84.Gilavand_2011_201.pdf","download_url":"https://www.academia.edu/attachments/105665679/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_The_Factors_Affecting_The_Gro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665679/84.Gilavand_2011_201-libre.pdf?1694442726=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_The_Factors_Affecting_The_Gro.pdf\u0026Expires=1732719331\u0026Signature=cu27lsJPNN9tULhS7GILY19gf6ZaAROHFXVSeGSyNiOLpMlHSC1vWZF7E0wb1gVqewt3cmPB~egwp9Vl6WoD9NglOsGzmm82ogdK2E1eXyF9WkPWV~urKgB9VXVCQG02JLVw9vjCtC9dDjJxwQhtMg1bgLCmdJMFFNCZOyaDz6nFIcmGKf7k9USlS2SkFiAcPiCJkxVlFEAJByvYbyfkKjbnYbGPpnrazc9gz-OTpC-srC6FwkyW7sbXAFfxb5qdP7MzYWebzlxHWlGhMW-rkReUvEQEZ96KIhHMKrjXnWIWYKea~GSljPrtND9rxljPHsBYo22xnGJZikZ-6Y2uoQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_Study_Of_The_Factors_Affecting_The_Growing_Presence_Of_Girls_In_Iranian_Universities_For_Continuing_Their_Higher_Education_A_Review","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":105665679,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665679/thumbnails/1.jpg","file_name":"84.Gilavand_2011_201.pdf","download_url":"https://www.academia.edu/attachments/105665679/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_The_Factors_Affecting_The_Gro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665679/84.Gilavand_2011_201-libre.pdf?1694442726=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_The_Factors_Affecting_The_Gro.pdf\u0026Expires=1732719331\u0026Signature=cu27lsJPNN9tULhS7GILY19gf6ZaAROHFXVSeGSyNiOLpMlHSC1vWZF7E0wb1gVqewt3cmPB~egwp9Vl6WoD9NglOsGzmm82ogdK2E1eXyF9WkPWV~urKgB9VXVCQG02JLVw9vjCtC9dDjJxwQhtMg1bgLCmdJMFFNCZOyaDz6nFIcmGKf7k9USlS2SkFiAcPiCJkxVlFEAJByvYbyfkKjbnYbGPpnrazc9gz-OTpC-srC6FwkyW7sbXAFfxb5qdP7MzYWebzlxHWlGhMW-rkReUvEQEZ96KIhHMKrjXnWIWYKea~GSljPrtND9rxljPHsBYo22xnGJZikZ-6Y2uoQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2621,"name":"Higher Education","url":"https://www.academia.edu/Documents/in/Higher_Education"}],"urls":[{"id":33883885,"url":"https://zenodo.org/record/1165235/files/84.Gilavand%2011%20(1).pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="106479371"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/106479371/A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information"><img alt="Research paper thumbnail of A Study Of Ahvaz Jundishapur University Of Medical Sciences Dental Students' Interest To Pursuing A Specialty According To Their Demographic Information" class="work-thumbnail" src="https://attachments.academia-assets.com/105665700/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/106479371/A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information">A Study Of Ahvaz Jundishapur University Of Medical Sciences Dental Students' Interest To Pursuing A Specialty According To Their Demographic Information</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Today, the changes in the expectations of the society from the dentists and the need for higher q...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Today, the changes in the expectations of the society from the dentists and the need for higher quality dental services have renewed the interests of people to pursue their education in the field of dental sciences. This study has tried to examine the degree of the students&#39; interest at Jundishapur University of Medical Sciences (AJUMS) to Pursuing a Specialty in the field of dental sciences according to their demographic data. This study is descriptive-analytical and has used a cross-sectional method of analysis during March 2015. The research population includes 484 of Professional Doctorate| (General) of dentistry students in the field of dental sciences at the university. Sampling was done by survey and questionnaire. Among all the students, 118 from the Faculty of Dental Sciences (tuition-free) and 58 from the Campus Unit (tuition-based) completed the questionnaire. To analyze the data descriptive statistics, frequency, frequency percentage, Kolmogorov–Smirnov test, and non...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4b8c95b08c6609f2cd755889e15fac68" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105665700,"asset_id":106479371,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105665700/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="106479371"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="106479371"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 106479371; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=106479371]").text(description); $(".js-view-count[data-work-id=106479371]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 106479371; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='106479371']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 106479371, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4b8c95b08c6609f2cd755889e15fac68" } } $('.js-work-strip[data-work-id=106479371]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":106479371,"title":"A Study Of Ahvaz Jundishapur University Of Medical Sciences Dental Students' Interest To Pursuing A Specialty According To Their Demographic Information","translated_title":"","metadata":{"abstract":"Today, the changes in the expectations of the society from the dentists and the need for higher quality dental services have renewed the interests of people to pursue their education in the field of dental sciences. 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To analyze the data descriptive statistics, frequency, frequency percentage, Kolmogorov–Smirnov test, and non...","publisher":"Zenodo","publication_date":{"day":27,"month":6,"year":2017,"errors":{}}},"translated_abstract":"Today, the changes in the expectations of the society from the dentists and the need for higher quality dental services have renewed the interests of people to pursue their education in the field of dental sciences. This study has tried to examine the degree of the students\u0026#39; interest at Jundishapur University of Medical Sciences (AJUMS) to Pursuing a Specialty in the field of dental sciences according to their demographic data. This study is descriptive-analytical and has used a cross-sectional method of analysis during March 2015. The research population includes 484 of Professional Doctorate| (General) of dentistry students in the field of dental sciences at the university. Sampling was done by survey and questionnaire. Among all the students, 118 from the Faculty of Dental Sciences (tuition-free) and 58 from the Campus Unit (tuition-based) completed the questionnaire. To analyze the data descriptive statistics, frequency, frequency percentage, Kolmogorov–Smirnov test, and non...","internal_url":"https://www.academia.edu/106479371/A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information","translated_internal_url":"","created_at":"2023-09-11T07:14:10.882-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105665700,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665700/thumbnails/1.jpg","file_name":"26.IAJPS26062017.pdf","download_url":"https://www.academia.edu/attachments/105665700/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_Ahvaz_Jundishapur_University.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665700/26.IAJPS26062017-libre.pdf?1694442724=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_Ahvaz_Jundishapur_University.pdf\u0026Expires=1732784475\u0026Signature=hA9zXLBj90ubvsKJ8qfFYp9jUCgBIZNVApwfceSqI-X4Kv3cmFQk4gHEkwkd1vupo-9k9IwvgUxVUO8GF1ze0F8UKindpm1uSWbtqIEPF2L9BoN00nEoEYP6SjKQAig~OzFQwMkguWK0WC6iAFDZCAEcWIUpPwiwZO1vnNVhfh6gf8mF50bfb3JNsJ42H8iDCX4Yew2gpjcHaNlAYtzEASPUh4s~QeK6fHyUTHg871SQJJKj0L4l41nUpCEP~~CyjPiAX-mifFVJe0G1EwOlgDvClbsf~ECp8N1V4mxEF9f8fPo44SL0c7o37jY3sO8~oq5S42ZdKK5QImHwPfflyw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_Study_Of_Ahvaz_Jundishapur_University_Of_Medical_Sciences_Dental_Students_Interest_To_Pursuing_A_Specialty_According_To_Their_Demographic_Information","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":105665700,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105665700/thumbnails/1.jpg","file_name":"26.IAJPS26062017.pdf","download_url":"https://www.academia.edu/attachments/105665700/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_Study_Of_Ahvaz_Jundishapur_University.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105665700/26.IAJPS26062017-libre.pdf?1694442724=\u0026response-content-disposition=attachment%3B+filename%3DA_Study_Of_Ahvaz_Jundishapur_University.pdf\u0026Expires=1732784475\u0026Signature=hA9zXLBj90ubvsKJ8qfFYp9jUCgBIZNVApwfceSqI-X4Kv3cmFQk4gHEkwkd1vupo-9k9IwvgUxVUO8GF1ze0F8UKindpm1uSWbtqIEPF2L9BoN00nEoEYP6SjKQAig~OzFQwMkguWK0WC6iAFDZCAEcWIUpPwiwZO1vnNVhfh6gf8mF50bfb3JNsJ42H8iDCX4Yew2gpjcHaNlAYtzEASPUh4s~QeK6fHyUTHg871SQJJKj0L4l41nUpCEP~~CyjPiAX-mifFVJe0G1EwOlgDvClbsf~ECp8N1V4mxEF9f8fPo44SL0c7o37jY3sO8~oq5S42ZdKK5QImHwPfflyw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":595,"name":"Medical Sciences","url":"https://www.academia.edu/Documents/in/Medical_Sciences"},{"id":4455,"name":"Medical Education","url":"https://www.academia.edu/Documents/in/Medical_Education"},{"id":85362,"name":"Descriptive Statistics","url":"https://www.academia.edu/Documents/in/Descriptive_Statistics"},{"id":2587767,"name":"Specialty","url":"https://www.academia.edu/Documents/in/Specialty"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85675791"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85675791/FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN" class="work-thumbnail" src="https://attachments.academia-assets.com/90301611/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85675791/FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN">FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. The clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter-and intra-subject variation in bioavailability from different commercial products. Moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. In the proposed research work, we are wanting to get ready transdermal patches of an antifungal drug Griseofulvin with the accompanying goal. Transdermal patches stacked with Griseofulvin will be arranged involving polymers in changing focus by dissolvable vanishing strategy.The prearranged transdermal patches will be assessed for different boundaries like weight variety, thickness, collapsing perseverance, drug content, level of dampness content, in-vitro drug release study</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2c821d1bc138ea0b0d47e89461bf0889" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90301611,"asset_id":85675791,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90301611/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85675791"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85675791"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85675791; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85675791]").text(description); $(".js-view-count[data-work-id=85675791]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85675791; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85675791']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85675791, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2c821d1bc138ea0b0d47e89461bf0889" } } $('.js-work-strip[data-work-id=85675791]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85675791,"title":"FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN","translated_title":"","metadata":{"doi":"10.5281/zenodo.7026047","abstract":"Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. The clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter-and intra-subject variation in bioavailability from different commercial products. Moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. In the proposed research work, we are wanting to get ready transdermal patches of an antifungal drug Griseofulvin with the accompanying goal. Transdermal patches stacked with Griseofulvin will be arranged involving polymers in changing focus by dissolvable vanishing strategy.The prearranged transdermal patches will be assessed for different boundaries like weight variety, thickness, collapsing perseverance, drug content, level of dampness content, in-vitro drug release study"},"translated_abstract":"Griseofulvin, an antifungal agent, is a BCS class II drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. The clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter-and intra-subject variation in bioavailability from different commercial products. Moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. In the proposed research work, we are wanting to get ready transdermal patches of an antifungal drug Griseofulvin with the accompanying goal. Transdermal patches stacked with Griseofulvin will be arranged involving polymers in changing focus by dissolvable vanishing strategy.The prearranged transdermal patches will be assessed for different boundaries like weight variety, thickness, collapsing perseverance, drug content, level of dampness content, in-vitro drug release study","internal_url":"https://www.academia.edu/85675791/FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN","translated_internal_url":"","created_at":"2022-08-26T10:30:41.969-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":38726710,"work_id":85675791,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":1651572,"email":"d***i@gmail.com","display_order":1,"name":"Singh Dangi","title":"FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN"},{"id":38726711,"work_id":85675791,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":6574262,"email":"p***5@gmail.com","display_order":2,"name":"Satkar Prasad","title":"FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES CONTAINING GRISEOFULVIN"}],"downloadable_attachments":[{"id":90301611,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301611/thumbnails/1.jpg","file_name":"31.IAJPS31082022.pdf","download_url":"https://www.academia.edu/attachments/90301611/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301611/31.IAJPS31082022-libre.pdf?1661536965=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf\u0026Expires=1732719332\u0026Signature=UCvrvf5pqb72DuxtyHElupqmSjZMtZaaGC9Ag-QL~XZaUVHMRycZ29aeO-RjMknLfOMTBrLC15YaDPmLstS5HXpj7OY-jhOfrkC2YfRUq~NuRFYG3-SDng5kyi7DQ7TawklyleGmKQem-fQ1Hd-pERrWgFYeaskR4JjND6HIj7twgtKdRoaFptWEvqKcgfXW5uhR-eChQ3Cb7dKS48JBQeiHcLcWlnnJFUg3~t-SCkUEI7mx9YII5ZV37XQKnzx0l2Xz79JnkBfbevLgYgF4pEMVzekeb~mfbfgTDRSxSBsgPDh3X7hr1~wMjaN-~dIfU3TCQz4niNQ-opFMZemw2g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_TRANSDERMAL_PATCHES_CONTAINING_GRISEOFULVIN","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90301611,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301611/thumbnails/1.jpg","file_name":"31.IAJPS31082022.pdf","download_url":"https://www.academia.edu/attachments/90301611/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301611/31.IAJPS31082022-libre.pdf?1661536965=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_TRANSDERMA.pdf\u0026Expires=1732719332\u0026Signature=UCvrvf5pqb72DuxtyHElupqmSjZMtZaaGC9Ag-QL~XZaUVHMRycZ29aeO-RjMknLfOMTBrLC15YaDPmLstS5HXpj7OY-jhOfrkC2YfRUq~NuRFYG3-SDng5kyi7DQ7TawklyleGmKQem-fQ1Hd-pERrWgFYeaskR4JjND6HIj7twgtKdRoaFptWEvqKcgfXW5uhR-eChQ3Cb7dKS48JBQeiHcLcWlnnJFUg3~t-SCkUEI7mx9YII5ZV37XQKnzx0l2Xz79JnkBfbevLgYgF4pEMVzekeb~mfbfgTDRSxSBsgPDh3X7hr1~wMjaN-~dIfU3TCQz4niNQ-opFMZemw2g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85675638"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85675638/EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES"><img alt="Research paper thumbnail of EVALUATION OF INVITRO ANTI-OXIDANT, TOTAL FLAVONOID CONTENT AND ANTI-MICROBIAL ACTIVITY OF SOLANUM SURATTENSE (WILD EGG PLANT) BURN LEAVES" class="work-thumbnail" src="https://attachments.academia-assets.com/90301401/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85675638/EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES">EVALUATION OF INVITRO ANTI-OXIDANT, TOTAL FLAVONOID CONTENT AND ANTI-MICROBIAL ACTIVITY OF SOLANUM SURATTENSE (WILD EGG PLANT) BURN LEAVES</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present research work relates to the preparation of ethanoic extraction of solanum surattense...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present research work relates to the preparation of ethanoic extraction of solanum surattense leaves and evaluation of extract for  the anti-oxidant and anti-microbial activity The phytochemical analysis of ethanolic extract solanum surattense has revealed the presence of various phytochemical constituents such as Alkaloids, Flavonoids, Saponins, sterols, carbohydrates, glycosides. The Antioxidant activity was analysed using hydrogen peroxide assay method  for the ethanolic  extracts of solanum  in concentrations of 10 - 50µg/Ml. The results revelaed that the ethanolic extract of solanum had showed the 60%  activity The prepared extract was evaluated for Antimicrobial  activity by using Agar well diffusion by Zone Inhibition method The antimicrobial of ethanolic exract of Solanum surattense leaves against two bacterial species at various concentrations were (20, 40,60,80,and 100µg/mL concentrations were evaluated. The results revealed that the Solanum surattense leaves showed good and better results for Antioxidant and Anti microbial activity. Thus it serves as an encouragement towards development of new drugs for the benefit of mankind.<br />Key words: solanum surattense, Leaves, Ethanolic extract, Anti-oxidant, Anti- microbial activity.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bcaf028e01904c487af3b1d20953dfef" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90301401,"asset_id":85675638,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90301401/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85675638"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85675638"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85675638; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85675638]").text(description); $(".js-view-count[data-work-id=85675638]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85675638; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85675638']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85675638, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bcaf028e01904c487af3b1d20953dfef" } } $('.js-work-strip[data-work-id=85675638]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85675638,"title":"EVALUATION OF INVITRO ANTI-OXIDANT, TOTAL FLAVONOID CONTENT AND ANTI-MICROBIAL ACTIVITY OF SOLANUM SURATTENSE (WILD EGG PLANT) BURN LEAVES","translated_title":"","metadata":{"doi":"10.5281/zenodo.7026040","abstract":"The present research work relates to the preparation of ethanoic extraction of solanum surattense leaves and evaluation of extract for the anti-oxidant and anti-microbial activity The phytochemical analysis of ethanolic extract solanum surattense has revealed the presence of various phytochemical constituents such as Alkaloids, Flavonoids, Saponins, sterols, carbohydrates, glycosides. The Antioxidant activity was analysed using hydrogen peroxide assay method for the ethanolic extracts of solanum in concentrations of 10 - 50µg/Ml. The results revelaed that the ethanolic extract of solanum had showed the 60% activity The prepared extract was evaluated for Antimicrobial activity by using Agar well diffusion by Zone Inhibition method The antimicrobial of ethanolic exract of Solanum surattense leaves against two bacterial species at various concentrations were (20, 40,60,80,and 100µg/mL concentrations were evaluated. The results revealed that the Solanum surattense leaves showed good and better results for Antioxidant and Anti microbial activity. Thus it serves as an encouragement towards development of new drugs for the benefit of mankind.\nKey words: solanum surattense, Leaves, Ethanolic extract, Anti-oxidant, Anti- microbial activity.\n"},"translated_abstract":"The present research work relates to the preparation of ethanoic extraction of solanum surattense leaves and evaluation of extract for the anti-oxidant and anti-microbial activity The phytochemical analysis of ethanolic extract solanum surattense has revealed the presence of various phytochemical constituents such as Alkaloids, Flavonoids, Saponins, sterols, carbohydrates, glycosides. The Antioxidant activity was analysed using hydrogen peroxide assay method for the ethanolic extracts of solanum in concentrations of 10 - 50µg/Ml. The results revelaed that the ethanolic extract of solanum had showed the 60% activity The prepared extract was evaluated for Antimicrobial activity by using Agar well diffusion by Zone Inhibition method The antimicrobial of ethanolic exract of Solanum surattense leaves against two bacterial species at various concentrations were (20, 40,60,80,and 100µg/mL concentrations were evaluated. The results revealed that the Solanum surattense leaves showed good and better results for Antioxidant and Anti microbial activity. Thus it serves as an encouragement towards development of new drugs for the benefit of mankind.\nKey words: solanum surattense, Leaves, Ethanolic extract, Anti-oxidant, Anti- microbial activity.\n","internal_url":"https://www.academia.edu/85675638/EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES","translated_internal_url":"","created_at":"2022-08-26T10:27:21.047-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90301401,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301401/thumbnails/1.jpg","file_name":"30.IAJPS30082022.pdf","download_url":"https://www.academia.edu/attachments/90301401/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301401/30.IAJPS30082022-libre.pdf?1661535903=\u0026response-content-disposition=attachment%3B+filename%3DEVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf\u0026Expires=1732784475\u0026Signature=UCrRpUkdR8WJ9s4TkFWCcQPs5eD99PNkbdQH4wE7EM834w5iBnQonmQRQAXBmpTeJ1anUsrzNRY1WxIUGaPSt422AKqgpmvWMIHky1UkH-5NWgo4COb21Uaz~QKhO3XxV97gWIkpF2GbeXpjSwFBpINPoeMxwxjC6S6aCwztOz2uFmy0yrCI614~3UCcOezrWj0ywwMkpaRkoSKiLdgjLmtktJJfOaN5AbzE~e2I11wuNVEdp7YxQETcWIkyILERu4TNCFgsVfw2t6iEZzjC9f5i9~QOYU~JYy03C5oH4JrYCxPJowX24RXE61LV6CxXO4MzAPBFg4TEel0MgZ1J7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL_FLAVONOID_CONTENT_AND_ANTI_MICROBIAL_ACTIVITY_OF_SOLANUM_SURATTENSE_WILD_EGG_PLANT_BURN_LEAVES","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90301401,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90301401/thumbnails/1.jpg","file_name":"30.IAJPS30082022.pdf","download_url":"https://www.academia.edu/attachments/90301401/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90301401/30.IAJPS30082022-libre.pdf?1661535903=\u0026response-content-disposition=attachment%3B+filename%3DEVALUATION_OF_INVITRO_ANTI_OXIDANT_TOTAL.pdf\u0026Expires=1732784475\u0026Signature=UCrRpUkdR8WJ9s4TkFWCcQPs5eD99PNkbdQH4wE7EM834w5iBnQonmQRQAXBmpTeJ1anUsrzNRY1WxIUGaPSt422AKqgpmvWMIHky1UkH-5NWgo4COb21Uaz~QKhO3XxV97gWIkpF2GbeXpjSwFBpINPoeMxwxjC6S6aCwztOz2uFmy0yrCI614~3UCcOezrWj0ywwMkpaRkoSKiLdgjLmtktJJfOaN5AbzE~e2I11wuNVEdp7YxQETcWIkyILERu4TNCFgsVfw2t6iEZzjC9f5i9~QOYU~JYy03C5oH4JrYCxPJowX24RXE61LV6CxXO4MzAPBFg4TEel0MgZ1J7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85586533"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85586533/STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES"><img alt="Research paper thumbnail of STANDARDIZATION AND MICROSCOPICAL EVALUATION STUDIES OF CENTELLA ASIATICA LINN. (BRAHMI) LEAVES" class="work-thumbnail" src="https://attachments.academia-assets.com/90238522/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85586533/STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES">STANDARDIZATION AND MICROSCOPICAL EVALUATION STUDIES OF CENTELLA ASIATICA LINN. (BRAHMI) LEAVES</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Based on trial-and-error experience and folk remedies continue to draw wide attention for their r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Based on trial-and-error experience and folk remedies continue to draw wide attention for their role in the treatment of mild and chronic diseases. We focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional systems of medicine. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in India. Triterpenoids, Saponins, the primary constituents of Centella asiatica are mainly believed to be responsible for its wide therapeutic actions. The herb is recommended for the treatment of various diseases like leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhea, fever, amenorrhea and Alzheimer's. The present work employs the standardization and microscopical evaluation of leaf drug to authenticate by methodological parameters ranges of Stomatal number, Vein islet number and Stomatal index of the crud drug. Respective practical and morphological parameters of the drug of Centella asiatica. Various microsopical parameters to evaluate the characteristics are reported, which is imperative for the safe utilization of the herb, are discussed.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="652e51428cdca04e6e7c75947a084140" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90238522,"asset_id":85586533,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90238522/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85586533"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85586533"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85586533; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85586533]").text(description); $(".js-view-count[data-work-id=85586533]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85586533; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85586533']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85586533, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "652e51428cdca04e6e7c75947a084140" } } $('.js-work-strip[data-work-id=85586533]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85586533,"title":"STANDARDIZATION AND MICROSCOPICAL EVALUATION STUDIES OF CENTELLA ASIATICA LINN. (BRAHMI) LEAVES","translated_title":"","metadata":{"doi":"10.5281/zenodo.7022696","abstract":"Based on trial-and-error experience and folk remedies continue to draw wide attention for their role in the treatment of mild and chronic diseases. We focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional systems of medicine. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in India. Triterpenoids, Saponins, the primary constituents of Centella asiatica are mainly believed to be responsible for its wide therapeutic actions. The herb is recommended for the treatment of various diseases like leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhea, fever, amenorrhea and Alzheimer's. The present work employs the standardization and microscopical evaluation of leaf drug to authenticate by methodological parameters ranges of Stomatal number, Vein islet number and Stomatal index of the crud drug. Respective practical and morphological parameters of the drug of Centella asiatica. Various microsopical parameters to evaluate the characteristics are reported, which is imperative for the safe utilization of the herb, are discussed."},"translated_abstract":"Based on trial-and-error experience and folk remedies continue to draw wide attention for their role in the treatment of mild and chronic diseases. We focus on plant research has increased all over the world and a large body of evidence has been accumulated to highlight the immense potential of medicinal plants used in various traditional systems of medicine. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in India. Triterpenoids, Saponins, the primary constituents of Centella asiatica are mainly believed to be responsible for its wide therapeutic actions. The herb is recommended for the treatment of various diseases like leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhea, fever, amenorrhea and Alzheimer's. The present work employs the standardization and microscopical evaluation of leaf drug to authenticate by methodological parameters ranges of Stomatal number, Vein islet number and Stomatal index of the crud drug. Respective practical and morphological parameters of the drug of Centella asiatica. Various microsopical parameters to evaluate the characteristics are reported, which is imperative for the safe utilization of the herb, are discussed.","internal_url":"https://www.academia.edu/85586533/STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES","translated_internal_url":"","created_at":"2022-08-25T03:47:59.000-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90238522,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238522/thumbnails/1.jpg","file_name":"25.IAJPS25082022.pdf","download_url":"https://www.academia.edu/attachments/90238522/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"STANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238522/25.IAJPS25082022-libre.pdf?1661437749=\u0026response-content-disposition=attachment%3B+filename%3DSTANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf\u0026Expires=1732784475\u0026Signature=cQvzFDTl37~sdWaw8KkSKMvpAPVms98KW315YzpHzV0Z7uvYe9UYZB8F8l~2GQNFGP5WonWxAm8b29ZliZKhbkGOn1pvt9BY9ioeJRmtQfwZ7cSrwx8cs5HtTkao7Yfk9OyRD7vh7jdaJieXShs~kbRfAlqKYUacE2YAR5NwBCDt6FPWBzkLudTxnR9YbYD2bvwqk~Kr-aWTDHllstV-7x-wsGl0Tma21uXPjTXr8Rf1r-u0KfeGKAFAe4LXJ4OjiVUTB94fxCSgZDBRJ92x82QZvCAxd~k9z7ngLOTU8kGs5VAR~f85GEAbj~oqoCL4vqgys-WKIMNIVxYz5AHB5A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"STANDARDIZATION_AND_MICROSCOPICAL_EVALUATION_STUDIES_OF_CENTELLA_ASIATICA_LINN_BRAHMI_LEAVES","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90238522,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238522/thumbnails/1.jpg","file_name":"25.IAJPS25082022.pdf","download_url":"https://www.academia.edu/attachments/90238522/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"STANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238522/25.IAJPS25082022-libre.pdf?1661437749=\u0026response-content-disposition=attachment%3B+filename%3DSTANDARDIZATION_AND_MICROSCOPICAL_EVALUA.pdf\u0026Expires=1732784475\u0026Signature=cQvzFDTl37~sdWaw8KkSKMvpAPVms98KW315YzpHzV0Z7uvYe9UYZB8F8l~2GQNFGP5WonWxAm8b29ZliZKhbkGOn1pvt9BY9ioeJRmtQfwZ7cSrwx8cs5HtTkao7Yfk9OyRD7vh7jdaJieXShs~kbRfAlqKYUacE2YAR5NwBCDt6FPWBzkLudTxnR9YbYD2bvwqk~Kr-aWTDHllstV-7x-wsGl0Tma21uXPjTXr8Rf1r-u0KfeGKAFAe4LXJ4OjiVUTB94fxCSgZDBRJ92x82QZvCAxd~k9z7ngLOTU8kGs5VAR~f85GEAbj~oqoCL4vqgys-WKIMNIVxYz5AHB5A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85586353"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85586353/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TERBUTALIINE SULFATE" class="work-thumbnail" src="https://attachments.academia-assets.com/90238323/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85586353/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE">FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TERBUTALIINE SULFATE</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The outcome of present work provides a concrete basis for development of fast dissolving tablets ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The outcome of present work provides a concrete basis for development of fast dissolving tablets of Terbutaline sulphate. Various approaches explored in the present work can be applied to achieve quick disintegration, good mouth feel and adequate mechanical strength, which improve patient compliance. Further work can be focused on co processing of various diluents with superdisintegrant. Some herbal superdisintegrant in freeze dried form can be investigated to determine their effect on disintegration time and hardness. To evaluate the effects of fast dissolving tablets in stress conditions, pharmacokinetic study can be performed in diseased state, and to compare with the results obtained in non- diseased state. All the researchers working on Terbutaline sulphate concentrates their research on the disintegration behavior of the tablets using super disintegrants which does not full fill the basic requirements of the mouth dissolving tablets i.e. patient compliance. Industries who want to make a Terbutaline sulphate blindly incorporating insoluble taste masking resins, superdisintegrants for disintegration and trading as mouth dissolving tablet. Due to lots of limitations like hardness, mechanical strength, no ease of manufacturing and most important cost of manufacturing, that’s why, industries concentrate whole emphasis on the use of superdisintegrants and make researchers not to work on mouth dissolving tablets instead moves on to mouth disintegrating tablets. Thus we concentrate on formulating mouth dissolving tablets giving complete dissolution of the formulation with minimum residue. <br />KEYWORDS- Terbutaline sulphate, Migraine, Mouth Dissolving Tablet, Croscarmellose Sodium, Crospovidone, Superdisintegrants.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="4f21d661b13beaaea9c73a5a4b8f7dc7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90238323,"asset_id":85586353,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90238323/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85586353"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85586353"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85586353; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85586353]").text(description); $(".js-view-count[data-work-id=85586353]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85586353; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85586353']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85586353, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "4f21d661b13beaaea9c73a5a4b8f7dc7" } } $('.js-work-strip[data-work-id=85586353]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85586353,"title":"FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TERBUTALIINE SULFATE","translated_title":"","metadata":{"doi":"10.5281/zenodo.7022693","abstract":"The outcome of present work provides a concrete basis for development of fast dissolving tablets of Terbutaline sulphate. Various approaches explored in the present work can be applied to achieve quick disintegration, good mouth feel and adequate mechanical strength, which improve patient compliance. Further work can be focused on co processing of various diluents with superdisintegrant. Some herbal superdisintegrant in freeze dried form can be investigated to determine their effect on disintegration time and hardness. To evaluate the effects of fast dissolving tablets in stress conditions, pharmacokinetic study can be performed in diseased state, and to compare with the results obtained in non- diseased state. All the researchers working on Terbutaline sulphate concentrates their research on the disintegration behavior of the tablets using super disintegrants which does not full fill the basic requirements of the mouth dissolving tablets i.e. patient compliance. Industries who want to make a Terbutaline sulphate blindly incorporating insoluble taste masking resins, superdisintegrants for disintegration and trading as mouth dissolving tablet. Due to lots of limitations like hardness, mechanical strength, no ease of manufacturing and most important cost of manufacturing, that’s why, industries concentrate whole emphasis on the use of superdisintegrants and make researchers not to work on mouth dissolving tablets instead moves on to mouth disintegrating tablets. Thus we concentrate on formulating mouth dissolving tablets giving complete dissolution of the formulation with minimum residue. \nKEYWORDS- Terbutaline sulphate, Migraine, Mouth Dissolving Tablet, Croscarmellose Sodium, Crospovidone, Superdisintegrants.\n","ai_title_tag":"Mouth Dissolving Tablets of Terbutaline Sulfate: Formulation \u0026 Evaluation"},"translated_abstract":"The outcome of present work provides a concrete basis for development of fast dissolving tablets of Terbutaline sulphate. Various approaches explored in the present work can be applied to achieve quick disintegration, good mouth feel and adequate mechanical strength, which improve patient compliance. Further work can be focused on co processing of various diluents with superdisintegrant. Some herbal superdisintegrant in freeze dried form can be investigated to determine their effect on disintegration time and hardness. To evaluate the effects of fast dissolving tablets in stress conditions, pharmacokinetic study can be performed in diseased state, and to compare with the results obtained in non- diseased state. All the researchers working on Terbutaline sulphate concentrates their research on the disintegration behavior of the tablets using super disintegrants which does not full fill the basic requirements of the mouth dissolving tablets i.e. patient compliance. Industries who want to make a Terbutaline sulphate blindly incorporating insoluble taste masking resins, superdisintegrants for disintegration and trading as mouth dissolving tablet. Due to lots of limitations like hardness, mechanical strength, no ease of manufacturing and most important cost of manufacturing, that’s why, industries concentrate whole emphasis on the use of superdisintegrants and make researchers not to work on mouth dissolving tablets instead moves on to mouth disintegrating tablets. Thus we concentrate on formulating mouth dissolving tablets giving complete dissolution of the formulation with minimum residue. \nKEYWORDS- Terbutaline sulphate, Migraine, Mouth Dissolving Tablet, Croscarmellose Sodium, Crospovidone, Superdisintegrants.\n","internal_url":"https://www.academia.edu/85586353/FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE","translated_internal_url":"","created_at":"2022-08-25T03:44:45.752-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90238323,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238323/thumbnails/1.jpg","file_name":"24.IAJPS24082022.pdf","download_url":"https://www.academia.edu/attachments/90238323/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238323/24.IAJPS24082022-libre.pdf?1661429042=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf\u0026Expires=1732784475\u0026Signature=fC0OOsDU7wvSc-JSnLlwKWbQ2-76WDg6x9e2OLQJb~awGIemWT5G7eg3iySiAbLoZ68RhHT2drhcOFHdMaLc3J3zTxNF-QJ4f~S2WS3zOTlc6V0GIwPlRMJgkbcTtPdseCpl12FJFY1m9DNDuIOKRCKloeI67f9ddxmqhSHz9LrJr2szM4MDp7ReAkgL-EsNZH~-CIzV3G0mhfHfuv4I5IuoEacyGx9u2S~azRZcMo9wcCE8hfp4ggcrVbGYuLTDAbtNB01YKGX6gUz08h8bQcffPRuo~X1z3otitvgt-VR~pjZH2L0Z-LbTjdJPybi7qhuw5yJniMG9UiO6lO3Low__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_MOUTH_DISSOLVING_TABLETS_OF_TERBUTALIINE_SULFATE","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90238323,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90238323/thumbnails/1.jpg","file_name":"24.IAJPS24082022.pdf","download_url":"https://www.academia.edu/attachments/90238323/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90238323/24.IAJPS24082022-libre.pdf?1661429042=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MOUTH_DISS.pdf\u0026Expires=1732784475\u0026Signature=fC0OOsDU7wvSc-JSnLlwKWbQ2-76WDg6x9e2OLQJb~awGIemWT5G7eg3iySiAbLoZ68RhHT2drhcOFHdMaLc3J3zTxNF-QJ4f~S2WS3zOTlc6V0GIwPlRMJgkbcTtPdseCpl12FJFY1m9DNDuIOKRCKloeI67f9ddxmqhSHz9LrJr2szM4MDp7ReAkgL-EsNZH~-CIzV3G0mhfHfuv4I5IuoEacyGx9u2S~azRZcMo9wcCE8hfp4ggcrVbGYuLTDAbtNB01YKGX6gUz08h8bQcffPRuo~X1z3otitvgt-VR~pjZH2L0Z-LbTjdJPybi7qhuw5yJniMG9UiO6lO3Low__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85540898"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85540898/MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW"><img alt="Research paper thumbnail of MASTECTOMY VS LUMPECTOMY RECURRENCE AND SURVIVAL RATES, A SYSTEMATIC REVIEW" class="work-thumbnail" src="https://attachments.academia-assets.com/90209461/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85540898/MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW">MASTECTOMY VS LUMPECTOMY RECURRENCE AND SURVIVAL RATES, A SYSTEMATIC REVIEW</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Respect to patient preference, a lumpectomy is one of the operations that has been pr...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Respect to patient preference, a lumpectomy is one of the operations that has been practised up to this point. In terms of mortality survival rate, it has both benefits and drawbacks. However, some breast cancer patients may experience a tumour recurrence following a lumpectomy, whether or not radiation was used to treat it.<br />Objectives: This study aims to assess and current evidences regarding overall survival (OS) and oncological outcomes of breast conservative treatment (lumpectomy) versus mastectomy.<br />Methods: For article selection, the PubMed database Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.<br />Conclusion: Half included studies reported equivalent results for both BCT and mastectomy. Yet, 6 studies against 3 were supporting BCT over mastectomy respectively in respect to patient diagnostic status and associated adjuvant treatment. However, BCT is the standard surgical technique for primary breast cancer and meets the preferences of the majority of breast cancer patients in terms of oncological safety and aesthetic outcome.<br />Keywords: breast cancer, lumpectomy, breast conservative treatment, mastectomy, overall survival, recurrence</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f8cef897f759dfc116e93f4970aefc7f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90209461,"asset_id":85540898,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90209461/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85540898"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85540898"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85540898; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85540898]").text(description); $(".js-view-count[data-work-id=85540898]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85540898; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85540898']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85540898, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f8cef897f759dfc116e93f4970aefc7f" } } $('.js-work-strip[data-work-id=85540898]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85540898,"title":"MASTECTOMY VS LUMPECTOMY RECURRENCE AND SURVIVAL RATES, A SYSTEMATIC REVIEW","translated_title":"","metadata":{"doi":"10.5281/zenodo.7020147","abstract":"Background: Respect to patient preference, a lumpectomy is one of the operations that has been practised up to this point. In terms of mortality survival rate, it has both benefits and drawbacks. However, some breast cancer patients may experience a tumour recurrence following a lumpectomy, whether or not radiation was used to treat it.\nObjectives: This study aims to assess and current evidences regarding overall survival (OS) and oncological outcomes of breast conservative treatment (lumpectomy) versus mastectomy.\nMethods: For article selection, the PubMed database Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.\nConclusion: Half included studies reported equivalent results for both BCT and mastectomy. Yet, 6 studies against 3 were supporting BCT over mastectomy respectively in respect to patient diagnostic status and associated adjuvant treatment. However, BCT is the standard surgical technique for primary breast cancer and meets the preferences of the majority of breast cancer patients in terms of oncological safety and aesthetic outcome.\nKeywords: breast cancer, lumpectomy, breast conservative treatment, mastectomy, overall survival, recurrence\n"},"translated_abstract":"Background: Respect to patient preference, a lumpectomy is one of the operations that has been practised up to this point. In terms of mortality survival rate, it has both benefits and drawbacks. However, some breast cancer patients may experience a tumour recurrence following a lumpectomy, whether or not radiation was used to treat it.\nObjectives: This study aims to assess and current evidences regarding overall survival (OS) and oncological outcomes of breast conservative treatment (lumpectomy) versus mastectomy.\nMethods: For article selection, the PubMed database Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.\nConclusion: Half included studies reported equivalent results for both BCT and mastectomy. Yet, 6 studies against 3 were supporting BCT over mastectomy respectively in respect to patient diagnostic status and associated adjuvant treatment. However, BCT is the standard surgical technique for primary breast cancer and meets the preferences of the majority of breast cancer patients in terms of oncological safety and aesthetic outcome.\nKeywords: breast cancer, lumpectomy, breast conservative treatment, mastectomy, overall survival, recurrence\n","internal_url":"https://www.academia.edu/85540898/MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW","translated_internal_url":"","created_at":"2022-08-24T11:17:31.520-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90209461,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90209461/thumbnails/1.jpg","file_name":"23.IAJPS23082022.pdf","download_url":"https://www.academia.edu/attachments/90209461/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90209461/23.IAJPS23082022-libre.pdf?1661368001=\u0026response-content-disposition=attachment%3B+filename%3DMASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf\u0026Expires=1732784475\u0026Signature=SdIyreji6qZK0l4wyghm6MHE-WEHOLraOokB-vtBer1no0D1EflvjdIOx6uUB~wyMJE8G1ONfS5Qysiqhm5Wfv07efbGJKrkkKa-7-nRee4~Ca-flrzVr4JjwgF0aUAf6voAOBV7IYUlfB5o-jgNS~-2BmnsJDXbyIxWXRk5qk8Iqss1wV42naAKjU5IEGLLDkDIzavcW9~-uofkYE1RGV1hCIFgkU5~keQYO8DzXdjqKV4tdZs7uLdXn5451wIyKsl3jDHf5WjEfExuIgsBMBL3S4S1p0MQL7gCjP49f23A4THMZ1Eh16YkP-9H0FpRbWJzwAj2qElTZ3~tkgoubA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND_SURVIVAL_RATES_A_SYSTEMATIC_REVIEW","translated_slug":"","page_count":12,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90209461,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90209461/thumbnails/1.jpg","file_name":"23.IAJPS23082022.pdf","download_url":"https://www.academia.edu/attachments/90209461/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"MASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90209461/23.IAJPS23082022-libre.pdf?1661368001=\u0026response-content-disposition=attachment%3B+filename%3DMASTECTOMY_VS_LUMPECTOMY_RECURRENCE_AND.pdf\u0026Expires=1732784475\u0026Signature=SdIyreji6qZK0l4wyghm6MHE-WEHOLraOokB-vtBer1no0D1EflvjdIOx6uUB~wyMJE8G1ONfS5Qysiqhm5Wfv07efbGJKrkkKa-7-nRee4~Ca-flrzVr4JjwgF0aUAf6voAOBV7IYUlfB5o-jgNS~-2BmnsJDXbyIxWXRk5qk8Iqss1wV42naAKjU5IEGLLDkDIzavcW9~-uofkYE1RGV1hCIFgkU5~keQYO8DzXdjqKV4tdZs7uLdXn5451wIyKsl3jDHf5WjEfExuIgsBMBL3S4S1p0MQL7gCjP49f23A4THMZ1Eh16YkP-9H0FpRbWJzwAj2qElTZ3~tkgoubA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2495116,"name":"Health \u0026 Medical Sciences","url":"https://www.academia.edu/Documents/in/Health_and_Medical_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85489632"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85489632/FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF HERBAL SCRUB" class="work-thumbnail" src="https://attachments.academia-assets.com/90173333/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85489632/FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB">FORMULATION AND EVALUATION OF HERBAL SCRUB</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, s...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, sebum other secretion Extends the skin and their appendix by chemical topical application. This is useful for making skin charming and beautiful. Cosmetic plays very important role in everyone’s life to make joyful skin. Nowadays herbal cosmeceuticals are in demand due to less or no side effect. Hebal cosmeceutical usually contain plant part which posses antimicrobial, antiaging, antiacne, antioxidant property. The number of research has studied rice benefit namely good nutritional value, resistance to high blood pressure. The problem like blackhead, whiteheads, acne might irritate nowadays here scrubbing become useful. For the healthy skin there is need of cleansing, removing dirt and debris. The current work is based on the formulation and evaluation of herbal facial scrub by using herbal drugs and evaluation is done by using various parameters. Thus prepared formulation use effectively to show the cleansing and glowing action. Using rice flour, lemon juice,Multani mitti, Neem Powder, Haldi, Tulsi, Mint, Carbopol 940, Gram flour, Sodium Benzoate, Sodium Lauryl Sulphate and Water, we Created four different formulation F1, F2, F3 and F4 for scrubbing and whitening. These formulation were then tested for various parameter, including Physical appearance, Homogeneity, Extrudability, Spreadability, Irritability, Washability, Grittiness, Foamability, Viscosity, Stability, Consistency.<br />KEYWORD: Scrubbing, cleansing, herbal, Antiacne, Whitening.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="438bc47df3cd4f67a618b08012c161cd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90173333,"asset_id":85489632,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90173333/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85489632"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85489632"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85489632; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85489632]").text(description); $(".js-view-count[data-work-id=85489632]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85489632; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85489632']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85489632, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "438bc47df3cd4f67a618b08012c161cd" } } $('.js-work-strip[data-work-id=85489632]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85489632,"title":"FORMULATION AND EVALUATION OF HERBAL SCRUB","translated_title":"","metadata":{"doi":"10.5281/zenodo.7018144","abstract":"For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, sebum other secretion Extends the skin and their appendix by chemical topical application. This is useful for making skin charming and beautiful. Cosmetic plays very important role in everyone’s life to make joyful skin. Nowadays herbal cosmeceuticals are in demand due to less or no side effect. Hebal cosmeceutical usually contain plant part which posses antimicrobial, antiaging, antiacne, antioxidant property. The number of research has studied rice benefit namely good nutritional value, resistance to high blood pressure. The problem like blackhead, whiteheads, acne might irritate nowadays here scrubbing become useful. For the healthy skin there is need of cleansing, removing dirt and debris. The current work is based on the formulation and evaluation of herbal facial scrub by using herbal drugs and evaluation is done by using various parameters. Thus prepared formulation use effectively to show the cleansing and glowing action. Using rice flour, lemon juice,Multani mitti, Neem Powder, Haldi, Tulsi, Mint, Carbopol 940, Gram flour, Sodium Benzoate, Sodium Lauryl Sulphate and Water, we Created four different formulation F1, F2, F3 and F4 for scrubbing and whitening. These formulation were then tested for various parameter, including Physical appearance, Homogeneity, Extrudability, Spreadability, Irritability, Washability, Grittiness, Foamability, Viscosity, Stability, Consistency.\nKEYWORD: Scrubbing, cleansing, herbal, Antiacne, Whitening. \n"},"translated_abstract":"For the healthy and nourish skin periodic cleansing requires which removes the dirt, dead skin, sebum other secretion Extends the skin and their appendix by chemical topical application. This is useful for making skin charming and beautiful. Cosmetic plays very important role in everyone’s life to make joyful skin. Nowadays herbal cosmeceuticals are in demand due to less or no side effect. Hebal cosmeceutical usually contain plant part which posses antimicrobial, antiaging, antiacne, antioxidant property. The number of research has studied rice benefit namely good nutritional value, resistance to high blood pressure. The problem like blackhead, whiteheads, acne might irritate nowadays here scrubbing become useful. For the healthy skin there is need of cleansing, removing dirt and debris. The current work is based on the formulation and evaluation of herbal facial scrub by using herbal drugs and evaluation is done by using various parameters. Thus prepared formulation use effectively to show the cleansing and glowing action. Using rice flour, lemon juice,Multani mitti, Neem Powder, Haldi, Tulsi, Mint, Carbopol 940, Gram flour, Sodium Benzoate, Sodium Lauryl Sulphate and Water, we Created four different formulation F1, F2, F3 and F4 for scrubbing and whitening. These formulation were then tested for various parameter, including Physical appearance, Homogeneity, Extrudability, Spreadability, Irritability, Washability, Grittiness, Foamability, Viscosity, Stability, Consistency.\nKEYWORD: Scrubbing, cleansing, herbal, Antiacne, Whitening. \n","internal_url":"https://www.academia.edu/85489632/FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB","translated_internal_url":"","created_at":"2022-08-23T22:37:47.737-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90173333,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90173333/thumbnails/1.jpg","file_name":"22.IAJPS22082022.pdf","download_url":"https://www.academia.edu/attachments/90173333/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90173333/22.IAJPS22082022-libre.pdf?1661322957=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf\u0026Expires=1732784475\u0026Signature=b64BNuQRVvgJumvUpOnFR4O7fVPMhBo5ggtCS8U8rEuBhVdfl3jPZavF0CJhvGiMNX~tf0OYIj33Z8-~MQ8ZTdE74Gk6eL9GMkmUr6aGlfQo0TNUqH-uvtLucPwTplZw~lHidybmyLSV4Y55Wqrdf38DeY8WRvVYAUiXSVQsgLqkYS073L3ZTP2~5m6xH2vNn5~ZSYDNjC2L0-qV0PsO6FSFOwd5M964T~GQ0no0bk8oUdbt9G96iFF9DknrUAHlm8QWyPbeK5bHKyRdIPi3TT2qXpv4w1yJkw7xsuff1N472nIrykkwn2OO3SHZNfGi3wdb17zNuK5g8NO3ipndbg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_HERBAL_SCRUB","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90173333,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90173333/thumbnails/1.jpg","file_name":"22.IAJPS22082022.pdf","download_url":"https://www.academia.edu/attachments/90173333/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90173333/22.IAJPS22082022-libre.pdf?1661322957=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_HERBAL_SCR.pdf\u0026Expires=1732784475\u0026Signature=b64BNuQRVvgJumvUpOnFR4O7fVPMhBo5ggtCS8U8rEuBhVdfl3jPZavF0CJhvGiMNX~tf0OYIj33Z8-~MQ8ZTdE74Gk6eL9GMkmUr6aGlfQo0TNUqH-uvtLucPwTplZw~lHidybmyLSV4Y55Wqrdf38DeY8WRvVYAUiXSVQsgLqkYS073L3ZTP2~5m6xH2vNn5~ZSYDNjC2L0-qV0PsO6FSFOwd5M964T~GQ0no0bk8oUdbt9G96iFF9DknrUAHlm8QWyPbeK5bHKyRdIPi3TT2qXpv4w1yJkw7xsuff1N472nIrykkwn2OO3SHZNfGi3wdb17zNuK5g8NO3ipndbg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85431600"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85431600/FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM"><img alt="Research paper thumbnail of FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM" class="work-thumbnail" src="https://attachments.academia-assets.com/90131192/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85431600/FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM">FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and HPMC K4M by direct compression method.The IR spectra revealed that, there was no interaction between polymers and drug. All polymers used were compatible with drug.All the prepared tablets were in acceptable range of weight variation, hardness, thickness, friability and drug content as per pharmacopoeial specification.The surface pH of prepared Buccal Patches was in the range of salivary pH, suggested that prepared tablets could be used without risk of mucosal irritation.All the Buccal Patches showed good residence time of 7.2 H to >10 h, indicated good adhesive capacity of polymers used.The CCD was used to find out the effect of independent varibles on the dependable variables. The result of CCD revealed that the locustbean gum and HPMC K4M have significant effect on the mucoadhesion strenth, swelling index, the drug release at 1 h and drug release at 8 h. The observed independent variables were found to be very close to predicted values of optimized formulation which demonstrates the feasibility of the optimization procedure in successful development of buccal tablet containing losartan potassium by using locustbean gum and HPMC K4M. The drug release form the optimized formula was found to be following the zero order kinetics and n value range of the Peppas equation is 0.521, which indicates fickian diffusion mechanism. Thus the release of drug from the dosage form was found to be time dependent.The stability studies revealed that there was no significant change in buccal tablet properties with aging at different storage conditions.Hence, the mucoadhesive Buccal Patches of losartan potassium can be prepared with enhanced bioavailability and prolonged therapeutic effect for the better management of hyper tension.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="dcff74c6b081a0d8f23ffef6576391fb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90131192,"asset_id":85431600,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90131192/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85431600"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85431600"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85431600; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85431600]").text(description); $(".js-view-count[data-work-id=85431600]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85431600; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85431600']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85431600, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "dcff74c6b081a0d8f23ffef6576391fb" } } $('.js-work-strip[data-work-id=85431600]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85431600,"title":"FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM","translated_title":"","metadata":{"doi":"10.5281/zenodo.7016528","abstract":"The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and HPMC K4M by direct compression method.The IR spectra revealed that, there was no interaction between polymers and drug. All polymers used were compatible with drug.All the prepared tablets were in acceptable range of weight variation, hardness, thickness, friability and drug content as per pharmacopoeial specification.The surface pH of prepared Buccal Patches was in the range of salivary pH, suggested that prepared tablets could be used without risk of mucosal irritation.All the Buccal Patches showed good residence time of 7.2 H to \u003e10 h, indicated good adhesive capacity of polymers used.The CCD was used to find out the effect of independent varibles on the dependable variables. The result of CCD revealed that the locustbean gum and HPMC K4M have significant effect on the mucoadhesion strenth, swelling index, the drug release at 1 h and drug release at 8 h. The observed independent variables were found to be very close to predicted values of optimized formulation which demonstrates the feasibility of the optimization procedure in successful development of buccal tablet containing losartan potassium by using locustbean gum and HPMC K4M. The drug release form the optimized formula was found to be following the zero order kinetics and n value range of the Peppas equation is 0.521, which indicates fickian diffusion mechanism. Thus the release of drug from the dosage form was found to be time dependent.The stability studies revealed that there was no significant change in buccal tablet properties with aging at different storage conditions.Hence, the mucoadhesive Buccal Patches of losartan potassium can be prepared with enhanced bioavailability and prolonged therapeutic effect for the better management of hyper tension."},"translated_abstract":"The mucoadhesive Buccal Patches of losartan potassium could be prepared using locustbean gum and HPMC K4M by direct compression method.The IR spectra revealed that, there was no interaction between polymers and drug. All polymers used were compatible with drug.All the prepared tablets were in acceptable range of weight variation, hardness, thickness, friability and drug content as per pharmacopoeial specification.The surface pH of prepared Buccal Patches was in the range of salivary pH, suggested that prepared tablets could be used without risk of mucosal irritation.All the Buccal Patches showed good residence time of 7.2 H to \u003e10 h, indicated good adhesive capacity of polymers used.The CCD was used to find out the effect of independent varibles on the dependable variables. The result of CCD revealed that the locustbean gum and HPMC K4M have significant effect on the mucoadhesion strenth, swelling index, the drug release at 1 h and drug release at 8 h. The observed independent variables were found to be very close to predicted values of optimized formulation which demonstrates the feasibility of the optimization procedure in successful development of buccal tablet containing losartan potassium by using locustbean gum and HPMC K4M. The drug release form the optimized formula was found to be following the zero order kinetics and n value range of the Peppas equation is 0.521, which indicates fickian diffusion mechanism. Thus the release of drug from the dosage form was found to be time dependent.The stability studies revealed that there was no significant change in buccal tablet properties with aging at different storage conditions.Hence, the mucoadhesive Buccal Patches of losartan potassium can be prepared with enhanced bioavailability and prolonged therapeutic effect for the better management of hyper tension.","internal_url":"https://www.academia.edu/85431600/FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM","translated_internal_url":"","created_at":"2022-08-23T03:19:11.399-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":38709673,"work_id":85431600,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":2760873,"email":"n***a@gmail.com","display_order":1,"name":"Nansri Saha","title":"FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM"},{"id":38709674,"work_id":85431600,"tagging_user_id":15402473,"tagged_user_id":null,"co_author_invite_id":7263053,"email":"r***9@gmail.com","display_order":2,"name":"Kummari Raju","title":"FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL PATCHES OF LOSARTAN POTASSIUM"}],"downloadable_attachments":[{"id":90131192,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131192/thumbnails/1.jpg","file_name":"21.IAJPS21082022.pdf","download_url":"https://www.academia.edu/attachments/90131192/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131192/21.IAJPS21082022-libre.pdf?1661251264=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf\u0026Expires=1732810433\u0026Signature=WzfuR~tY02k32zlB1L7qyYyGeb9o9pMjJmC0TpDAT~gtXqud8jZgmycDnly3UagX7FEtlocUEEXfOzwj8GhWvtBD9paodqDFfHgrfNdJy22HPROLSmA9LTIfg7hZBUGk8dWpFOswS8GotG-ylY4NcuVHMhlJdQXscioFZGXQubRSx2efyLKk-sUTwBHP-S-P9zuYCVatTrytta6uEUoUaJ3WpXxOkcmbqmD3~JhNjs5YyJvVtwci1NzS6YFMEluXde3ZUDuk18KJ7OKyKvZNXR7hosKAla0Sec1xmDrmhmfVn52n4OoqpsHkss9CXfR5zLSCJeMXchkhtPIDT85u1Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FORMULATION_AND_EVALUATION_OF_MUCOADHESIVE_BUCCAL_PATCHES_OF_LOSARTAN_POTASSIUM","translated_slug":"","page_count":22,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"NERLa0ZVemo3b2V2ZnhvclJSV1hLVkIySmZoWHhUTGdkM0RrRkZzclVQUHBsQnlCZkE1dVlTdU5PNzdNb0hmSy0tWFl5NXlHVmV4c2ZHRk5mbW45TFFpZz09--55aa7bd5a34b9da9e36f7e4857b57c514dec1744"},"attachments":[{"id":90131192,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131192/thumbnails/1.jpg","file_name":"21.IAJPS21082022.pdf","download_url":"https://www.academia.edu/attachments/90131192/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131192/21.IAJPS21082022-libre.pdf?1661251264=\u0026response-content-disposition=attachment%3B+filename%3DFORMULATION_AND_EVALUATION_OF_MUCOADHESI.pdf\u0026Expires=1732810433\u0026Signature=WzfuR~tY02k32zlB1L7qyYyGeb9o9pMjJmC0TpDAT~gtXqud8jZgmycDnly3UagX7FEtlocUEEXfOzwj8GhWvtBD9paodqDFfHgrfNdJy22HPROLSmA9LTIfg7hZBUGk8dWpFOswS8GotG-ylY4NcuVHMhlJdQXscioFZGXQubRSx2efyLKk-sUTwBHP-S-P9zuYCVatTrytta6uEUoUaJ3WpXxOkcmbqmD3~JhNjs5YyJvVtwci1NzS6YFMEluXde3ZUDuk18KJ7OKyKvZNXR7hosKAla0Sec1xmDrmhmfVn52n4OoqpsHkss9CXfR5zLSCJeMXchkhtPIDT85u1Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85431427"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85431427/POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE"><img alt="Research paper thumbnail of POST COVID DEPRESSION: A REVIEW OF LITERATURE" class="work-thumbnail" src="https://attachments.academia-assets.com/90131073/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85431427/POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE">POST COVID DEPRESSION: A REVIEW OF LITERATURE</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pai...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pain, headache, diarrhea, rhinorrhea, loss of smell and taste. In addition, there are more and more reports of mental health problems in people who have survived SARS-CoV-2 infection. The most frequently described mental disorders are major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorders (OCD) and insomnia. MDD is hypothesized to be an active inflammatory process with elevated pro- and anti-inflammatory cytokines and oxidative stress. Depression is a leading cause of disability globally. Accordingly, depressive symptoms and clinically-significant depression in post-COVID-19 syndrome may have severe implications as it relates to quality-of-life outcomes. There is also a lack of comprehensive studies directly linking MDD and its biomarkers to COVID-19. Furthermore, it remains to be determined whether the high frequency of depression among individuals with post-COVID-19 syndrome is a long-term consequence of the viral infection or a result of the social and/or economic outcomes of the pandemic. <br />Keywords: Corona virus; Depression; Post Covid; Major Depressive Episode.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="2b05bc5697eadccd3b6f11963e94ed22" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90131073,"asset_id":85431427,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90131073/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85431427"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85431427"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85431427; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85431427]").text(description); $(".js-view-count[data-work-id=85431427]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85431427; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85431427']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85431427, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "2b05bc5697eadccd3b6f11963e94ed22" } } $('.js-work-strip[data-work-id=85431427]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85431427,"title":"POST COVID DEPRESSION: A REVIEW OF LITERATURE","translated_title":"","metadata":{"doi":"10.5281/zenodo.7016526","abstract":"The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pain, headache, diarrhea, rhinorrhea, loss of smell and taste. In addition, there are more and more reports of mental health problems in people who have survived SARS-CoV-2 infection. The most frequently described mental disorders are major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorders (OCD) and insomnia. MDD is hypothesized to be an active inflammatory process with elevated pro- and anti-inflammatory cytokines and oxidative stress. Depression is a leading cause of disability globally. Accordingly, depressive symptoms and clinically-significant depression in post-COVID-19 syndrome may have severe implications as it relates to quality-of-life outcomes. There is also a lack of comprehensive studies directly linking MDD and its biomarkers to COVID-19. Furthermore, it remains to be determined whether the high frequency of depression among individuals with post-COVID-19 syndrome is a long-term consequence of the viral infection or a result of the social and/or economic outcomes of the pandemic. \nKeywords: Corona virus; Depression; Post Covid; Major Depressive Episode.\n"},"translated_abstract":"The most common symptoms of coronavirus disease are fever, cough, shortness of breath, muscle pain, headache, diarrhea, rhinorrhea, loss of smell and taste. In addition, there are more and more reports of mental health problems in people who have survived SARS-CoV-2 infection. The most frequently described mental disorders are major depressive disorder (MDD), post-traumatic stress disorder (PTSD), anxiety disorders, obsessive-compulsive disorders (OCD) and insomnia. MDD is hypothesized to be an active inflammatory process with elevated pro- and anti-inflammatory cytokines and oxidative stress. Depression is a leading cause of disability globally. Accordingly, depressive symptoms and clinically-significant depression in post-COVID-19 syndrome may have severe implications as it relates to quality-of-life outcomes. There is also a lack of comprehensive studies directly linking MDD and its biomarkers to COVID-19. Furthermore, it remains to be determined whether the high frequency of depression among individuals with post-COVID-19 syndrome is a long-term consequence of the viral infection or a result of the social and/or economic outcomes of the pandemic. \nKeywords: Corona virus; Depression; Post Covid; Major Depressive Episode.\n","internal_url":"https://www.academia.edu/85431427/POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE","translated_internal_url":"","created_at":"2022-08-23T03:16:53.796-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90131073,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131073/thumbnails/1.jpg","file_name":"20.IAJPS20082022.pdf","download_url":"https://www.academia.edu/attachments/90131073/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"POST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131073/20.IAJPS20082022-libre.pdf?1661251258=\u0026response-content-disposition=attachment%3B+filename%3DPOST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf\u0026Expires=1732810433\u0026Signature=T9s3JJc7~jGRRMMHL-C0CwIRy6kZs74naLQelzsI8vrz0QkQY6kIX1PKJSKL-hx3r06lt~KaYzcJIKUi3-mSt4Aa3rGbkVZ4qlm-Q~kEuG2Zzq-hxPnJTjHDxCt8ReP~KxCIHk3MqxAwi9pG8rArf6OV0Bv36opswppV8BDWSsv6L4LuytQGToEo2fh~K1MDQUKLKzTvGEgyM8T9BF4YYcXDvN7Ww5~jsDs4SPNN7~qqmUDcIUojPINBL58cTRUmJb9rqM9jTb7~L6k~vQRJm1kvBaGwrjM8Qr6uoZX7HriJyC9~BC0J92RKdOtQ7j0nejX2BdM9Vx8886m3dKJFpw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"POST_COVID_DEPRESSION_A_REVIEW_OF_LITERATURE","translated_slug":"","page_count":3,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"RlNQMDhBTityY0JWc3pLVHhvcGlnTFliaXk2bTFtV3JmWTBJYlR3QU1ZMnpFdDk2Rm1XZ3A2bXppWXJKTFJQZC0tcndSTXZRaWVZK0lDZzl6THFwNldUUT09--808f1c5c14933cd472fa67fc26628bd2e0b040f6"},"attachments":[{"id":90131073,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90131073/thumbnails/1.jpg","file_name":"20.IAJPS20082022.pdf","download_url":"https://www.academia.edu/attachments/90131073/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"POST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90131073/20.IAJPS20082022-libre.pdf?1661251258=\u0026response-content-disposition=attachment%3B+filename%3DPOST_COVID_DEPRESSION_A_REVIEW_OF_LITERA.pdf\u0026Expires=1732810433\u0026Signature=T9s3JJc7~jGRRMMHL-C0CwIRy6kZs74naLQelzsI8vrz0QkQY6kIX1PKJSKL-hx3r06lt~KaYzcJIKUi3-mSt4Aa3rGbkVZ4qlm-Q~kEuG2Zzq-hxPnJTjHDxCt8ReP~KxCIHk3MqxAwi9pG8rArf6OV0Bv36opswppV8BDWSsv6L4LuytQGToEo2fh~K1MDQUKLKzTvGEgyM8T9BF4YYcXDvN7Ww5~jsDs4SPNN7~qqmUDcIUojPINBL58cTRUmJb9rqM9jTb7~L6k~vQRJm1kvBaGwrjM8Qr6uoZX7HriJyC9~BC0J92RKdOtQ7j0nejX2BdM9Vx8886m3dKJFpw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85431255"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85431255/EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA"><img alt="Research paper thumbnail of EFFECT OF MARIJUANA USE FOR PAIN RELIEF IN PATIENTS WITH FIBROMYALGIA" class="work-thumbnail" src="https://attachments.academia-assets.com/90130946/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85431255/EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA">EFFECT OF MARIJUANA USE FOR PAIN RELIEF IN PATIENTS WITH FIBROMYALGIA</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. H...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. Herbal cannabis or marijuana has been used for the treatment of pain for centuries. This is noteworthy that in recent times its use has been mostly outside traditional medicine. In this study, we audit and conducted a review of the studies and patients with confirmed history of fibromyalgia and the effects of marijuana (Medical Cannabis-MC) for the pain relief, was documented and discussed. Despite lingering controversy, the use of botanical cannabis for medicinal purposes represents the revival of a plant with historical significance reemerging in present day health care. MC appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.<br />Keywords: Fibromyalgia; Marijuana; Medical Cannabis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b8c9479f9b243ef74d0197be7bdf772e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90130946,"asset_id":85431255,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90130946/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85431255"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85431255"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85431255; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85431255]").text(description); $(".js-view-count[data-work-id=85431255]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85431255; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85431255']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85431255, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b8c9479f9b243ef74d0197be7bdf772e" } } $('.js-work-strip[data-work-id=85431255]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85431255,"title":"EFFECT OF MARIJUANA USE FOR PAIN RELIEF IN PATIENTS WITH FIBROMYALGIA","translated_title":"","metadata":{"doi":"10.5281/zenodo.7016509","abstract":"There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. Herbal cannabis or marijuana has been used for the treatment of pain for centuries. This is noteworthy that in recent times its use has been mostly outside traditional medicine. In this study, we audit and conducted a review of the studies and patients with confirmed history of fibromyalgia and the effects of marijuana (Medical Cannabis-MC) for the pain relief, was documented and discussed. Despite lingering controversy, the use of botanical cannabis for medicinal purposes represents the revival of a plant with historical significance reemerging in present day health care. MC appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.\nKeywords: Fibromyalgia; Marijuana; Medical Cannabis.\n"},"translated_abstract":"There are only a few studies in the literature on the use of cannabis by fibromyalgia patients. Herbal cannabis or marijuana has been used for the treatment of pain for centuries. This is noteworthy that in recent times its use has been mostly outside traditional medicine. In this study, we audit and conducted a review of the studies and patients with confirmed history of fibromyalgia and the effects of marijuana (Medical Cannabis-MC) for the pain relief, was documented and discussed. Despite lingering controversy, the use of botanical cannabis for medicinal purposes represents the revival of a plant with historical significance reemerging in present day health care. MC appears to be a safe and effective alternative for the treatment of fibromyalgia symptoms.\nKeywords: Fibromyalgia; Marijuana; Medical Cannabis.\n","internal_url":"https://www.academia.edu/85431255/EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA","translated_internal_url":"","created_at":"2022-08-23T03:14:01.339-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90130946,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90130946/thumbnails/1.jpg","file_name":"19.IAJPS19082022.pdf","download_url":"https://www.academia.edu/attachments/90130946/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90130946/19.IAJPS19082022-libre.pdf?1661251276=\u0026response-content-disposition=attachment%3B+filename%3DEFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf\u0026Expires=1732810433\u0026Signature=XSdo0Vy~xJ0ycHtd7kLKr6n18iCjy7Yu4knRlql~5c~mnzwS~wyiwRCBlh4G2lmHN~LaJoHv6rzLMyKQOKlFdyn~hZwDFx5LYJkexinbT9VV30f3S0c-0AJJhf7aL6VVZ2szPn8UkcG7F7BdHEEcwi0C4xHF5lxSzryOq-8F0J7WXy27QPfG6R1RFUolJyUUYFY5jJWmQguOmob502E7F-SjJP-dcMiqbRXaj29~-w7qnQnZ8gDHy42cb~y3~kxHiDjxKu-mplTRxpOeNFaUVlPHQST5W8ReByarOKzZ8X57InhkLYFYCo~vDFd1n6dp6ojGFuxvuO3jPOULSbbdKQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF_IN_PATIENTS_WITH_FIBROMYALGIA","translated_slug":"","page_count":4,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"aytzVXlDYlI4R3dMY2RkaHA3VmZjY2N3TnN1THZHVWZ1RjN0anB6MUdTSGVicmNadnYwaWhwdTJkY2pUZ0k2ai0tYWZZWW9QN2xaOEd4a08yUnlhcWkzUT09--fc68acc4d8337b44d05761503b19c98d0ae4a450"},"attachments":[{"id":90130946,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90130946/thumbnails/1.jpg","file_name":"19.IAJPS19082022.pdf","download_url":"https://www.academia.edu/attachments/90130946/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"EFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90130946/19.IAJPS19082022-libre.pdf?1661251276=\u0026response-content-disposition=attachment%3B+filename%3DEFFECT_OF_MARIJUANA_USE_FOR_PAIN_RELIEF.pdf\u0026Expires=1732810433\u0026Signature=XSdo0Vy~xJ0ycHtd7kLKr6n18iCjy7Yu4knRlql~5c~mnzwS~wyiwRCBlh4G2lmHN~LaJoHv6rzLMyKQOKlFdyn~hZwDFx5LYJkexinbT9VV30f3S0c-0AJJhf7aL6VVZ2szPn8UkcG7F7BdHEEcwi0C4xHF5lxSzryOq-8F0J7WXy27QPfG6R1RFUolJyUUYFY5jJWmQguOmob502E7F-SjJP-dcMiqbRXaj29~-w7qnQnZ8gDHy42cb~y3~kxHiDjxKu-mplTRxpOeNFaUVlPHQST5W8ReByarOKzZ8X57InhkLYFYCo~vDFd1n6dp6ojGFuxvuO3jPOULSbbdKQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85132256"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85132256/A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL"><img alt="Research paper thumbnail of A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG- DRUG INTERACTIONS IN CARDIAC PATIENTS AT A TERTIARY CARE HOSPITAL" class="work-thumbnail" src="https://attachments.academia-assets.com/89926329/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85132256/A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL">A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG- DRUG INTERACTIONS IN CARDIAC PATIENTS AT A TERTIARY CARE HOSPITAL</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in card...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in cardiac patients. Method: This study was carried out for duration of 6 months at the inpatient department of General medicine in Osmania general hospital, Afzalgunj, Hyderabad. The data of 75 patients was collected and the frequently occurring drug-drug interactions among the selected patients were noted. <br />Results: The study identified various drug-drug interactions in cardiac patients with minor drug interactions being more common (52%). The subjects were distributed on the basis of age, gender, diagnosis and number of drugs used. The cardiovascular drugs prescribed were Anticoagulants (25.7%), Anti hyper lipidemics (21.3%), Diuretics (16.9%) and Calcium channel blockers (13.2%), ACE-inhibitors (9.5%), Vasodilators (6.6%) and Angiotensin receptor blockers (6.6%). <br />Conclusion: The present study shows that DDI’s are frequent among hospitalized cardiac patients and highlights the need to screen prescriptions of cardiovascular patients for DDI’s, as this helps in detection and prevention of possible adverse drug interactions.Thus, this study assists in understanding the factors associated with DDI’s that can help in safe and effective use of drugs in future. <br />Key words: Drug-drug interactions, cardiovascular, patients, adverse drug.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="21039455981591ed20e0e27ccf4caa6f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89926329,"asset_id":85132256,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89926329/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85132256"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85132256"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85132256; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85132256]").text(description); $(".js-view-count[data-work-id=85132256]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85132256; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85132256']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85132256, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "21039455981591ed20e0e27ccf4caa6f" } } $('.js-work-strip[data-work-id=85132256]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85132256,"title":"A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG- DRUG INTERACTIONS IN CARDIAC PATIENTS AT A TERTIARY CARE HOSPITAL","translated_title":"","metadata":{"doi":"10.5281/zenodo.7009588","abstract":"Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in cardiac patients. Method: This study was carried out for duration of 6 months at the inpatient department of General medicine in Osmania general hospital, Afzalgunj, Hyderabad. The data of 75 patients was collected and the frequently occurring drug-drug interactions among the selected patients were noted. \nResults: The study identified various drug-drug interactions in cardiac patients with minor drug interactions being more common (52%). The subjects were distributed on the basis of age, gender, diagnosis and number of drugs used. The cardiovascular drugs prescribed were Anticoagulants (25.7%), Anti hyper lipidemics (21.3%), Diuretics (16.9%) and Calcium channel blockers (13.2%), ACE-inhibitors (9.5%), Vasodilators (6.6%) and Angiotensin receptor blockers (6.6%). \nConclusion: The present study shows that DDI’s are frequent among hospitalized cardiac patients and highlights the need to screen prescriptions of cardiovascular patients for DDI’s, as this helps in detection and prevention of possible adverse drug interactions.Thus, this study assists in understanding the factors associated with DDI’s that can help in safe and effective use of drugs in future. \nKey words: Drug-drug interactions, cardiovascular, patients, adverse drug. \n"},"translated_abstract":"Aim:To study the occurrence, frequency and severity of significant drug-drug interactions in cardiac patients. Method: This study was carried out for duration of 6 months at the inpatient department of General medicine in Osmania general hospital, Afzalgunj, Hyderabad. The data of 75 patients was collected and the frequently occurring drug-drug interactions among the selected patients were noted. \nResults: The study identified various drug-drug interactions in cardiac patients with minor drug interactions being more common (52%). The subjects were distributed on the basis of age, gender, diagnosis and number of drugs used. The cardiovascular drugs prescribed were Anticoagulants (25.7%), Anti hyper lipidemics (21.3%), Diuretics (16.9%) and Calcium channel blockers (13.2%), ACE-inhibitors (9.5%), Vasodilators (6.6%) and Angiotensin receptor blockers (6.6%). \nConclusion: The present study shows that DDI’s are frequent among hospitalized cardiac patients and highlights the need to screen prescriptions of cardiovascular patients for DDI’s, as this helps in detection and prevention of possible adverse drug interactions.Thus, this study assists in understanding the factors associated with DDI’s that can help in safe and effective use of drugs in future. \nKey words: Drug-drug interactions, cardiovascular, patients, adverse drug. \n","internal_url":"https://www.academia.edu/85132256/A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL","translated_internal_url":"","created_at":"2022-08-19T05:00:28.079-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89926329,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89926329/thumbnails/1.jpg","file_name":"18.IAJPS18082022.pdf","download_url":"https://www.academia.edu/attachments/89926329/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89926329/18.IAJPS18082022-libre.pdf?1660910729=\u0026response-content-disposition=attachment%3B+filename%3DA_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf\u0026Expires=1732784475\u0026Signature=Zs2ngrlsFHt2YGh6lTs5iFW0RfTrYjusi9C8HocTOkPB7E301p2D67f1-K8uMAcOiwVIuiP91mieLKFnM0Tp4I0xFO3rdFWardlq1Mnyix3Alo4LZ8Q0zTGa2Ob9W2~0GkjF1I-95PjOyiBo8l8q2zOSd7qHAXdAG8pjRpYQaLKhL-r6NYZ0GdRm8Nizelxc2ir3hmNG7~hXY0iCRHJV~HJmJfBLvv36CDiDcUqNkLVRI7xCCGL2JFuDYDnN1XjXsAYAGR4QX-fwzDZvtJ42wAtlkTOvGF8daCuvhXntfRQ61YzhkJhC2Mu997QV1Gbb443mkyMXi-T2fDaDJu1~gw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRUG_DRUG_INTERACTIONS_IN_CARDIAC_PATIENTS_AT_A_TERTIARY_CARE_HOSPITAL","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89926329,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89926329/thumbnails/1.jpg","file_name":"18.IAJPS18082022.pdf","download_url":"https://www.academia.edu/attachments/89926329/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"A_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89926329/18.IAJPS18082022-libre.pdf?1660910729=\u0026response-content-disposition=attachment%3B+filename%3DA_PROSPECTIVE_OBSERVATIONAL_STUDY_ON_DRU.pdf\u0026Expires=1732784475\u0026Signature=Zs2ngrlsFHt2YGh6lTs5iFW0RfTrYjusi9C8HocTOkPB7E301p2D67f1-K8uMAcOiwVIuiP91mieLKFnM0Tp4I0xFO3rdFWardlq1Mnyix3Alo4LZ8Q0zTGa2Ob9W2~0GkjF1I-95PjOyiBo8l8q2zOSd7qHAXdAG8pjRpYQaLKhL-r6NYZ0GdRm8Nizelxc2ir3hmNG7~hXY0iCRHJV~HJmJfBLvv36CDiDcUqNkLVRI7xCCGL2JFuDYDnN1XjXsAYAGR4QX-fwzDZvtJ42wAtlkTOvGF8daCuvhXntfRQ61YzhkJhC2Mu997QV1Gbb443mkyMXi-T2fDaDJu1~gw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="85132056"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/85132056/COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_"><img alt="Research paper thumbnail of COMPETITIVE REPLACEMENT OF OBNOXIOUS WEEDS PARTHENIUM HYSTEROPHORUS THROUGH SOME INDIGENOUS, TRADITIONAL & MEDICINAL WILD WEEDS, IN ITS NATURAL HABITAT OF MALWA REGION, MADHYA PRADESH (INDIA)." class="work-thumbnail" src="https://attachments.academia-assets.com/90011439/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/85132056/COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_">COMPETITIVE REPLACEMENT OF OBNOXIOUS WEEDS PARTHENIUM HYSTEROPHORUS THROUGH SOME INDIGENOUS, TRADITIONAL & MEDICINAL WILD WEEDS, IN ITS NATURAL HABITAT OF MALWA REGION, MADHYA PRADESH (INDIA).</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A field experiment has been conducted to assess the potential of some medicinally important weed ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A field experiment has been conducted to assess the potential of some medicinally important weed plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera on the removal of Congress grass. Parthenium necessary grass evil in herbs; it can cause toxic effects and serious diseases on human and animal health. Parthenium hysterophorous is a strong intraspecific competitor for native natural weeds and all herbaceous plants. It is a worldwide problem because native herbaceous plants reduce day by day through intraspecific competitive activity. The authors have traced and surveyed this problem and selected local native plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera, and conducted experiments for three consecutive years (2009, 2010, and 2011) in the Malwa region of Madhya Pradesh India. During the three years of the study period, observed (20) significant reduction in the density of obnoxious Parthenium weed by producing fast competition through selected all three native weeds and respectively by increasing the density of C. occidentalis (5.84) < C. tora (5.1) < A. aspera (3.3). <br />Keywords: Achyranthus aspera, Cassia tora, Cassia occidentalis, Congress grass, Parthenium, and Obnoxious weeds.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9569e79b32c2135bbdad27f692d9bd3b" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":90011439,"asset_id":85132056,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/90011439/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="85132056"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="85132056"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 85132056; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=85132056]").text(description); $(".js-view-count[data-work-id=85132056]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 85132056; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='85132056']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 85132056, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9569e79b32c2135bbdad27f692d9bd3b" } } $('.js-work-strip[data-work-id=85132056]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":85132056,"title":"COMPETITIVE REPLACEMENT OF OBNOXIOUS WEEDS PARTHENIUM HYSTEROPHORUS THROUGH SOME INDIGENOUS, TRADITIONAL \u0026 MEDICINAL WILD WEEDS, IN ITS NATURAL HABITAT OF MALWA REGION, MADHYA PRADESH (INDIA).","translated_title":"","metadata":{"doi":"10.5281/zenodo.7009368","abstract":"A field experiment has been conducted to assess the potential of some medicinally important weed plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera on the removal of Congress grass. Parthenium necessary grass evil in herbs; it can cause toxic effects and serious diseases on human and animal health. Parthenium hysterophorous is a strong intraspecific competitor for native natural weeds and all herbaceous plants. It is a worldwide problem because native herbaceous plants reduce day by day through intraspecific competitive activity. The authors have traced and surveyed this problem and selected local native plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera, and conducted experiments for three consecutive years (2009, 2010, and 2011) in the Malwa region of Madhya Pradesh India. During the three years of the study period, observed (20) significant reduction in the density of obnoxious Parthenium weed by producing fast competition through selected all three native weeds and respectively by increasing the density of C. occidentalis (5.84) \u003c C. tora (5.1) \u003c A. aspera (3.3). \nKeywords: Achyranthus aspera, Cassia tora, Cassia occidentalis, Congress grass, Parthenium, and Obnoxious weeds.\n"},"translated_abstract":"A field experiment has been conducted to assess the potential of some medicinally important weed plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera on the removal of Congress grass. Parthenium necessary grass evil in herbs; it can cause toxic effects and serious diseases on human and animal health. Parthenium hysterophorous is a strong intraspecific competitor for native natural weeds and all herbaceous plants. It is a worldwide problem because native herbaceous plants reduce day by day through intraspecific competitive activity. The authors have traced and surveyed this problem and selected local native plant species viz. Cassia tora, Cassia occidentalis, and Achyranthus aspera, and conducted experiments for three consecutive years (2009, 2010, and 2011) in the Malwa region of Madhya Pradesh India. During the three years of the study period, observed (20) significant reduction in the density of obnoxious Parthenium weed by producing fast competition through selected all three native weeds and respectively by increasing the density of C. occidentalis (5.84) \u003c C. tora (5.1) \u003c A. aspera (3.3). \nKeywords: Achyranthus aspera, Cassia tora, Cassia occidentalis, Congress grass, Parthenium, and Obnoxious weeds.\n","internal_url":"https://www.academia.edu/85132056/COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_","translated_internal_url":"","created_at":"2022-08-19T04:57:28.515-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":90011439,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90011439/thumbnails/1.jpg","file_name":"17.IAJPS17082022.pdf","download_url":"https://www.academia.edu/attachments/90011439/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90011439/17.IAJPS17082022-libre.pdf?1661068504=\u0026response-content-disposition=attachment%3B+filename%3DCOMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf\u0026Expires=1732784476\u0026Signature=SB8KowC9GDnVABR1TiKgiOE0azvt~a1i2DrPNGiRKMHUc7C3lBLdceefol3AjJ3OA0frt8daaQyzaeA7BLwHRHUyZZYmttTGAg76mFn1C2ynRGXUyD4zFiS3ztPl2xhI3OzcNeidTVKef2HO3VKwkW2ycMxgccMieyL9jfKQ6WTdEA5dAYH6TgaZPl46LmMCmsKl3uI0s8HoRz3kA-EdlFVRZ~9~lp0bXzO8Us0B2K1Vlrfnnhu~1pvmE6ZIbE5eMIky1hq8C-mX~KD1BnIUI34W3krdZhnf0FFuX8qAk0Bx6moGr1bPVFpH0EcBvADuHdqEvayk32KdTPqnxwx~Bw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEEDS_PARTHENIUM_HYSTEROPHORUS_THROUGH_SOME_INDIGENOUS_TRADITIONAL_and_MEDICINAL_WILD_WEEDS_IN_ITS_NATURAL_HABITAT_OF_MALWA_REGION_MADHYA_PRADESH_INDIA_","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":90011439,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/90011439/thumbnails/1.jpg","file_name":"17.IAJPS17082022.pdf","download_url":"https://www.academia.edu/attachments/90011439/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"COMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/90011439/17.IAJPS17082022-libre.pdf?1661068504=\u0026response-content-disposition=attachment%3B+filename%3DCOMPETITIVE_REPLACEMENT_OF_OBNOXIOUS_WEE.pdf\u0026Expires=1732784476\u0026Signature=SB8KowC9GDnVABR1TiKgiOE0azvt~a1i2DrPNGiRKMHUc7C3lBLdceefol3AjJ3OA0frt8daaQyzaeA7BLwHRHUyZZYmttTGAg76mFn1C2ynRGXUyD4zFiS3ztPl2xhI3OzcNeidTVKef2HO3VKwkW2ycMxgccMieyL9jfKQ6WTdEA5dAYH6TgaZPl46LmMCmsKl3uI0s8HoRz3kA-EdlFVRZ~9~lp0bXzO8Us0B2K1Vlrfnnhu~1pvmE6ZIbE5eMIky1hq8C-mX~KD1BnIUI34W3krdZhnf0FFuX8qAk0Bx6moGr1bPVFpH0EcBvADuHdqEvayk32KdTPqnxwx~Bw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84990395"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84990395/FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION"><img alt="Research paper thumbnail of FLOATING MICROSPHERES ENCAPSULATING CARVEDILOL FOR EFFECTIVE MANAGEMENT OF HYPERTENSION" class="work-thumbnail" src="https://attachments.academia-assets.com/89829516/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84990395/FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION">FLOATING MICROSPHERES ENCAPSULATING CARVEDILOL FOR EFFECTIVE MANAGEMENT OF HYPERTENSION</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The objective of the present study was to formulate and evaluate floating microspheres of carvedi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The objective of the present study was to formulate and evaluate floating microspheres of carvedilol. Carvedilol has a terminal half-life of 7-10 hr, but most of the drug is eliminated with a half-life of about 2hr.Besidesbeingabeneficialdrugcomparedtoother drugs of the same class, it has narrow absorption window in upper part of the gastro intestinal tract, hence a floating drug delivery system is preferred, such that the formulation will be available for a longer duration than usual for absorption. Floating microspheres were prepared by emulsion solvent diffusion method using ethanol and dichloromethane as solvents. Ethyl cellulose and Hydroxy propyl methyl cellulose, HPMC K 4 M, were used to prolong the release of the drug from microspheres. The prepared microspheres were subjected to various evaluatory studies. All the microspheres were found to have a size in the range of 20-40 μ and were nearly spherical in shape. For optimization of Formulation F1 (EudragitRS100), F2 (Acrycoat S 100) and F3 (Cellulose Acetate) was selected.  The formulation F1 prepared using EudragitRS100 showed 82.5±2.76 percentage drug release AFTER 24 Hrs. as compare to other formulations.<br />Key words: Carvedilol, Floating microspheres, Hypertension</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f0db93f6adf85f8535de59ab5f4a1efb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89829516,"asset_id":84990395,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89829516/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84990395"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84990395"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84990395; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84990395]").text(description); $(".js-view-count[data-work-id=84990395]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84990395; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84990395']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84990395, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f0db93f6adf85f8535de59ab5f4a1efb" } } $('.js-work-strip[data-work-id=84990395]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84990395,"title":"FLOATING MICROSPHERES ENCAPSULATING CARVEDILOL FOR EFFECTIVE MANAGEMENT OF HYPERTENSION","translated_title":"","metadata":{"doi":"10.5281/zenodo.7004318","abstract":"The objective of the present study was to formulate and evaluate floating microspheres of carvedilol. Carvedilol has a terminal half-life of 7-10 hr, but most of the drug is eliminated with a half-life of about 2hr.Besidesbeingabeneficialdrugcomparedtoother drugs of the same class, it has narrow absorption window in upper part of the gastro intestinal tract, hence a floating drug delivery system is preferred, such that the formulation will be available for a longer duration than usual for absorption. Floating microspheres were prepared by emulsion solvent diffusion method using ethanol and dichloromethane as solvents. Ethyl cellulose and Hydroxy propyl methyl cellulose, HPMC K 4 M, were used to prolong the release of the drug from microspheres. The prepared microspheres were subjected to various evaluatory studies. All the microspheres were found to have a size in the range of 20-40 μ and were nearly spherical in shape. For optimization of Formulation F1 (EudragitRS100), F2 (Acrycoat S 100) and F3 (Cellulose Acetate) was selected. The formulation F1 prepared using EudragitRS100 showed 82.5±2.76 percentage drug release AFTER 24 Hrs. as compare to other formulations.\nKey words: Carvedilol, Floating microspheres, Hypertension\n"},"translated_abstract":"The objective of the present study was to formulate and evaluate floating microspheres of carvedilol. Carvedilol has a terminal half-life of 7-10 hr, but most of the drug is eliminated with a half-life of about 2hr.Besidesbeingabeneficialdrugcomparedtoother drugs of the same class, it has narrow absorption window in upper part of the gastro intestinal tract, hence a floating drug delivery system is preferred, such that the formulation will be available for a longer duration than usual for absorption. Floating microspheres were prepared by emulsion solvent diffusion method using ethanol and dichloromethane as solvents. Ethyl cellulose and Hydroxy propyl methyl cellulose, HPMC K 4 M, were used to prolong the release of the drug from microspheres. The prepared microspheres were subjected to various evaluatory studies. All the microspheres were found to have a size in the range of 20-40 μ and were nearly spherical in shape. For optimization of Formulation F1 (EudragitRS100), F2 (Acrycoat S 100) and F3 (Cellulose Acetate) was selected. The formulation F1 prepared using EudragitRS100 showed 82.5±2.76 percentage drug release AFTER 24 Hrs. as compare to other formulations.\nKey words: Carvedilol, Floating microspheres, Hypertension\n","internal_url":"https://www.academia.edu/84990395/FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION","translated_internal_url":"","created_at":"2022-08-17T09:10:16.853-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89829516,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829516/thumbnails/1.jpg","file_name":"16.IAJPS16082022.pdf","download_url":"https://www.academia.edu/attachments/89829516/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829516/16.IAJPS16082022-libre.pdf?1660754686=\u0026response-content-disposition=attachment%3B+filename%3DFLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf\u0026Expires=1732784476\u0026Signature=CbFVJ5fq6DDvjidAxZWQSLhwfe4s0PEXRdX-2CiCZmxr5iCpnbvPWspXvw5yuI5uHTvkvx3W8nJQ217FTw40J35p6f5BxAaKogtQ8eGkr1hTdeZyJ~9I1O1kHtc2oFmPPQp~NiWxSAzI6Swm2lKy0K~za0mKI8IsJhfll-LFElkUGWbNYrpydE29Y1-85WSLqba-b0Twkq6LQP9sufI2Ma6GC0UnwF9saqTlY3HFjIHiR30ZcU60pUy2PrxMaWroxeJCdWunT~eGqKPlPmEvNVAVl4XxDY7j-d0btOROUg~BctDhIt~oyCmBpcptyIEJ5DOLkTBs7jXJQPyAQ~iUEw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FLOATING_MICROSPHERES_ENCAPSULATING_CARVEDILOL_FOR_EFFECTIVE_MANAGEMENT_OF_HYPERTENSION","translated_slug":"","page_count":4,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89829516,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829516/thumbnails/1.jpg","file_name":"16.IAJPS16082022.pdf","download_url":"https://www.academia.edu/attachments/89829516/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829516/16.IAJPS16082022-libre.pdf?1660754686=\u0026response-content-disposition=attachment%3B+filename%3DFLOATING_MICROSPHERES_ENCAPSULATING_CARV.pdf\u0026Expires=1732784476\u0026Signature=CbFVJ5fq6DDvjidAxZWQSLhwfe4s0PEXRdX-2CiCZmxr5iCpnbvPWspXvw5yuI5uHTvkvx3W8nJQ217FTw40J35p6f5BxAaKogtQ8eGkr1hTdeZyJ~9I1O1kHtc2oFmPPQp~NiWxSAzI6Swm2lKy0K~za0mKI8IsJhfll-LFElkUGWbNYrpydE29Y1-85WSLqba-b0Twkq6LQP9sufI2Ma6GC0UnwF9saqTlY3HFjIHiR30ZcU60pUy2PrxMaWroxeJCdWunT~eGqKPlPmEvNVAVl4XxDY7j-d0btOROUg~BctDhIt~oyCmBpcptyIEJ5DOLkTBs7jXJQPyAQ~iUEw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84990215"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84990215/PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA"><img alt="Research paper thumbnail of PHYTOCHEMICAL SCREENING AND IN-VIVO ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF MORINGA OLEIFERA" class="work-thumbnail" src="https://attachments.academia-assets.com/89829350/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84990215/PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA">PHYTOCHEMICAL SCREENING AND IN-VIVO ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF MORINGA OLEIFERA</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarmi...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. Moringa oleifera (M. oleifera) popularly known as miracle tree belongs to the family Moringaceae.  It  is  a  medicinal  plant  in  which  the  leaves  are  the  most  nutritious  part,  being  a  significant  source  of  vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. This study investigated the protective and ameliorative potential of ethanol extract of M. oleifera leaf (50-200mg/kg) on alloxan-induced diabetes in Wistar rats. Qualitative analysis of various phytochemical constituents was determined by the well-known test protocol available in the literature. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats. Glucose concentrations in extract, glibenclamide or metformin post-alloxan administered rats were decreased compared to diabetic rats. But they were higher than control, except by day 14 wherein glucose level was normal or lower. When compared with glibenclamide or metformin, glucose levels of extract treated animals were higher on the 7th day, but lower at the end of treatment. In addition, extract treatment caused hypoglycemia after fourteen days of treatment in normal rats. The results demonstrate that M. oleifera leaf possesses protective and ameliorative antidiabetic potential in rats.<br />Keywords: Diabetes mellitus, Moringa oleifera, Phytochemical screening, Alloxan monohydrate.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6e1be523c003786fd6262e3aefb732d6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89829350,"asset_id":84990215,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89829350/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84990215"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84990215"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84990215; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84990215]").text(description); $(".js-view-count[data-work-id=84990215]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84990215; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84990215']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84990215, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6e1be523c003786fd6262e3aefb732d6" } } $('.js-work-strip[data-work-id=84990215]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84990215,"title":"PHYTOCHEMICAL SCREENING AND IN-VIVO ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF MORINGA OLEIFERA","translated_title":"","metadata":{"doi":"10.5281/zenodo.7004288","abstract":"Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. Moringa oleifera (M. oleifera) popularly known as miracle tree belongs to the family Moringaceae. It is a medicinal plant in which the leaves are the most nutritious part, being a significant source of vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. This study investigated the protective and ameliorative potential of ethanol extract of M. oleifera leaf (50-200mg/kg) on alloxan-induced diabetes in Wistar rats. Qualitative analysis of various phytochemical constituents was determined by the well-known test protocol available in the literature. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats. Glucose concentrations in extract, glibenclamide or metformin post-alloxan administered rats were decreased compared to diabetic rats. But they were higher than control, except by day 14 wherein glucose level was normal or lower. When compared with glibenclamide or metformin, glucose levels of extract treated animals were higher on the 7th day, but lower at the end of treatment. In addition, extract treatment caused hypoglycemia after fourteen days of treatment in normal rats. The results demonstrate that M. oleifera leaf possesses protective and ameliorative antidiabetic potential in rats.\nKeywords: Diabetes mellitus, Moringa oleifera, Phytochemical screening, Alloxan monohydrate.\n"},"translated_abstract":"Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. Moringa oleifera (M. oleifera) popularly known as miracle tree belongs to the family Moringaceae. It is a medicinal plant in which the leaves are the most nutritious part, being a significant source of vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. This study investigated the protective and ameliorative potential of ethanol extract of M. oleifera leaf (50-200mg/kg) on alloxan-induced diabetes in Wistar rats. Qualitative analysis of various phytochemical constituents was determined by the well-known test protocol available in the literature. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats. Glucose concentrations in extract, glibenclamide or metformin post-alloxan administered rats were decreased compared to diabetic rats. But they were higher than control, except by day 14 wherein glucose level was normal or lower. When compared with glibenclamide or metformin, glucose levels of extract treated animals were higher on the 7th day, but lower at the end of treatment. In addition, extract treatment caused hypoglycemia after fourteen days of treatment in normal rats. The results demonstrate that M. oleifera leaf possesses protective and ameliorative antidiabetic potential in rats.\nKeywords: Diabetes mellitus, Moringa oleifera, Phytochemical screening, Alloxan monohydrate.\n","internal_url":"https://www.academia.edu/84990215/PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA","translated_internal_url":"","created_at":"2022-08-17T09:07:38.611-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89829350,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829350/thumbnails/1.jpg","file_name":"15.IAJPS15082022.pdf","download_url":"https://www.academia.edu/attachments/89829350/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829350/15.IAJPS15082022-libre.pdf?1660754687=\u0026response-content-disposition=attachment%3B+filename%3DPHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf\u0026Expires=1732810433\u0026Signature=IkauyKrUmDN1~3~zTm8HCdhoI1TzpCCEhWvQ6K2L5M6rLVm-iDugeKm-ooYCi~TPFtd9hcjc-6b36T5X4qEh5yscPYyNGcUcqjoPouwXzQStivHmTzcbXK6qm0oMt-K5UoE9uGFpYPwV59q0oHG1voWddHDjcc1ZvriHZAI6qyJ9QhhTfmSOTL7~nU8Vbr1ufiF8AZACoQPqV2JZGLaelqS4ecGMbPN~r6rRsg6M-AXbbazhb7jaIPvDy1nMgYyybDnkP6R~KYotAeesAx9Cha3Y8rT23Fo0Sh9T5FwAl-RrswfAWDb35NQz5ufXzWlCimq90zx9Rznc4Y9ZoyLjHQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTIDIABETIC_ACTIVITY_OF_ETHANOLIC_EXTRACT_OF_LEAVES_OF_MORINGA_OLEIFERA","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"ZmtnM0d0L3IvaTFvVDhMb2JEYUZsYWZoWjVSMEl3OHh2dWRvdGlGaWFQN05maHdlb20vK0tib0owYlk0L2FRMC0tdHJPQVIvK1dmNnJvR2RvUytGN0VyUT09--0d85adcbbaf572910cfa71275da26fda1f66fee0"},"attachments":[{"id":89829350,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89829350/thumbnails/1.jpg","file_name":"15.IAJPS15082022.pdf","download_url":"https://www.academia.edu/attachments/89829350/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"PHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89829350/15.IAJPS15082022-libre.pdf?1660754687=\u0026response-content-disposition=attachment%3B+filename%3DPHYTOCHEMICAL_SCREENING_AND_IN_VIVO_ANTI.pdf\u0026Expires=1732810433\u0026Signature=IkauyKrUmDN1~3~zTm8HCdhoI1TzpCCEhWvQ6K2L5M6rLVm-iDugeKm-ooYCi~TPFtd9hcjc-6b36T5X4qEh5yscPYyNGcUcqjoPouwXzQStivHmTzcbXK6qm0oMt-K5UoE9uGFpYPwV59q0oHG1voWddHDjcc1ZvriHZAI6qyJ9QhhTfmSOTL7~nU8Vbr1ufiF8AZACoQPqV2JZGLaelqS4ecGMbPN~r6rRsg6M-AXbbazhb7jaIPvDy1nMgYyybDnkP6R~KYotAeesAx9Cha3Y8rT23Fo0Sh9T5FwAl-RrswfAWDb35NQz5ufXzWlCimq90zx9Rznc4Y9ZoyLjHQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84888529"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84888529/DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC"><img alt="Research paper thumbnail of DEVELOPMENT AND EVALUATION OF OSMOTIC PUMP TABLETS OF ACECLOFENAC" class="work-thumbnail" src="https://attachments.academia-assets.com/89760828/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84888529/DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC">DEVELOPMENT AND EVALUATION OF OSMOTIC PUMP TABLETS OF ACECLOFENAC</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The aim of the work is to develop & evaluate bilayer-core osmotic pump tablet by wet granulation ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The aim of the work is to develop & evaluate bilayer-core osmotic pump tablet by wet granulation method, using Aceclofenac as model drug. The prepared bilayer- core osmotic pump tablet will be evaluated for influence of sodium chloride, PEO (WSR Coagulant) and PEG level on drug release profile, etc. The granules of drug layer and push layer were prepared separately by wet granulation method using isopropyl alcohol. The prepared osmotic tablet of Aceclofenac was coated using ethyl cellulose as semi permeable membrane and PEG 400 as pore forming agent, the prepared tablets were evaluated for bulk density, tapped density, compressibility index, angle of repose, weight variation test, hardness, friability, content uniformity and In vitro drug release studied using USP XXIX Paddle method; formulated tablets were also evaluated for effect of pH, effect of agitation, FTIR, the results of IR study showed that there is no interaction between osmo agent, and pure drug. <br />Results showed that as the concentration of the sodium chloride and PEO (WSR Coagulant) increases it affects the in vitro drug release. Formulation F6 prepared with sodium chloride 65mg, PEO (WSR Coagulant) 37.5mg which exhibited excellent micro meritic properties, percentage yield, and percentage drug release 84.089 % for a period of 12 hrs.Osmotic tablets of Aceclofenac may be an effective alternative to conventional dosage form, which can be effectively used in the treatment of Rheumatoid arthritis. <br />Keywords:  Osmogent, Osmotic pump tablets, Aceclofenac, disintegration time.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ee4afcfdaa1f093b39a0cb556b7379f5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89760828,"asset_id":84888529,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89760828/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84888529"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84888529"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84888529; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84888529]").text(description); $(".js-view-count[data-work-id=84888529]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84888529; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84888529']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84888529, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ee4afcfdaa1f093b39a0cb556b7379f5" } } $('.js-work-strip[data-work-id=84888529]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84888529,"title":"DEVELOPMENT AND EVALUATION OF OSMOTIC PUMP TABLETS OF ACECLOFENAC","translated_title":"","metadata":{"doi":"10.5281/zenodo.6998101","abstract":"The aim of the work is to develop \u0026 evaluate bilayer-core osmotic pump tablet by wet granulation method, using Aceclofenac as model drug. The prepared bilayer- core osmotic pump tablet will be evaluated for influence of sodium chloride, PEO (WSR Coagulant) and PEG level on drug release profile, etc. The granules of drug layer and push layer were prepared separately by wet granulation method using isopropyl alcohol. The prepared osmotic tablet of Aceclofenac was coated using ethyl cellulose as semi permeable membrane and PEG 400 as pore forming agent, the prepared tablets were evaluated for bulk density, tapped density, compressibility index, angle of repose, weight variation test, hardness, friability, content uniformity and In vitro drug release studied using USP XXIX Paddle method; formulated tablets were also evaluated for effect of pH, effect of agitation, FTIR, the results of IR study showed that there is no interaction between osmo agent, and pure drug. \nResults showed that as the concentration of the sodium chloride and PEO (WSR Coagulant) increases it affects the in vitro drug release. Formulation F6 prepared with sodium chloride 65mg, PEO (WSR Coagulant) 37.5mg which exhibited excellent micro meritic properties, percentage yield, and percentage drug release 84.089 % for a period of 12 hrs.Osmotic tablets of Aceclofenac may be an effective alternative to conventional dosage form, which can be effectively used in the treatment of Rheumatoid arthritis. \nKeywords: Osmogent, Osmotic pump tablets, Aceclofenac, disintegration time.\n"},"translated_abstract":"The aim of the work is to develop \u0026 evaluate bilayer-core osmotic pump tablet by wet granulation method, using Aceclofenac as model drug. The prepared bilayer- core osmotic pump tablet will be evaluated for influence of sodium chloride, PEO (WSR Coagulant) and PEG level on drug release profile, etc. The granules of drug layer and push layer were prepared separately by wet granulation method using isopropyl alcohol. The prepared osmotic tablet of Aceclofenac was coated using ethyl cellulose as semi permeable membrane and PEG 400 as pore forming agent, the prepared tablets were evaluated for bulk density, tapped density, compressibility index, angle of repose, weight variation test, hardness, friability, content uniformity and In vitro drug release studied using USP XXIX Paddle method; formulated tablets were also evaluated for effect of pH, effect of agitation, FTIR, the results of IR study showed that there is no interaction between osmo agent, and pure drug. \nResults showed that as the concentration of the sodium chloride and PEO (WSR Coagulant) increases it affects the in vitro drug release. Formulation F6 prepared with sodium chloride 65mg, PEO (WSR Coagulant) 37.5mg which exhibited excellent micro meritic properties, percentage yield, and percentage drug release 84.089 % for a period of 12 hrs.Osmotic tablets of Aceclofenac may be an effective alternative to conventional dosage form, which can be effectively used in the treatment of Rheumatoid arthritis. \nKeywords: Osmogent, Osmotic pump tablets, Aceclofenac, disintegration time.\n","internal_url":"https://www.academia.edu/84888529/DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC","translated_internal_url":"","created_at":"2022-08-16T06:40:17.014-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89760828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89760828/thumbnails/1.jpg","file_name":"14.IAJPS14082022.pdf","download_url":"https://www.academia.edu/attachments/89760828/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89760828/14.IAJPS14082022-libre.pdf?1660658204=\u0026response-content-disposition=attachment%3B+filename%3DDEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf\u0026Expires=1732632476\u0026Signature=WMkGeacUCnyrsFWkA9Vqxd2VLJ0wi5j6PNYWrtCfKR4COEvTkP1HW6L5Zj1rQhxK-zBuxSYDf0PFJfxB1iWZft0P9e7g8kPm5uM9FTsTZhB5kQIWuyM5N-cQRjNjWEIeqFvqYQ~ikqUjWxAL7h9jG~M1csPITTy30RcobbtQyuk-T-2wxkgdu0C3JtWgcN-Dgo-SxXMixiRlHFRyViDvh5uTDPXogxwSTtJwgFl9Ki8O16pTNNiT3N2VKntWZAdVIxa4zGvVD1lvmy7QveVZuR5jdZGz0pwDKl39i2KquHlA7l-hCzD3oJNw7FOgcZzlWg9gnfJVSAy7Wc0Qn4xA5Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PUMP_TABLETS_OF_ACECLOFENAC","translated_slug":"","page_count":19,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89760828,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89760828/thumbnails/1.jpg","file_name":"14.IAJPS14082022.pdf","download_url":"https://www.academia.edu/attachments/89760828/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"DEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89760828/14.IAJPS14082022-libre.pdf?1660658204=\u0026response-content-disposition=attachment%3B+filename%3DDEVELOPMENT_AND_EVALUATION_OF_OSMOTIC_PU.pdf\u0026Expires=1732632476\u0026Signature=WMkGeacUCnyrsFWkA9Vqxd2VLJ0wi5j6PNYWrtCfKR4COEvTkP1HW6L5Zj1rQhxK-zBuxSYDf0PFJfxB1iWZft0P9e7g8kPm5uM9FTsTZhB5kQIWuyM5N-cQRjNjWEIeqFvqYQ~ikqUjWxAL7h9jG~M1csPITTy30RcobbtQyuk-T-2wxkgdu0C3JtWgcN-Dgo-SxXMixiRlHFRyViDvh5uTDPXogxwSTtJwgFl9Ki8O16pTNNiT3N2VKntWZAdVIxa4zGvVD1lvmy7QveVZuR5jdZGz0pwDKl39i2KquHlA7l-hCzD3oJNw7FOgcZzlWg9gnfJVSAy7Wc0Qn4xA5Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84557260"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84557260/ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER"><img alt="Research paper thumbnail of ANTI-TUMOR ACTIVITY OF MERCAPTOPURINE IN COMBINATION WITH PEPPER" class="work-thumbnail" src="https://attachments.academia-assets.com/89538157/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84557260/ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER">ANTI-TUMOR ACTIVITY OF MERCAPTOPURINE IN COMBINATION WITH PEPPER</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Cancer is one of the most life-threatening diseases and serious health problem in both developing...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Cancer is one of the most life-threatening diseases and serious health problem in both developing and developed countries. Many synthetic and chemotherapeutic agents used in cancer therapy are having low bioavailability and involve the risk of life-threatening host toxicity. Modern researchers are increasingly showing interest toward the improvement of bioavailability of a large number of drugs by addition of various herbs with bioenhancing properties. In oral drug delivery system, the co-administration of therapeutic agents with natural compounds possessing absorption improving activities, has also garnered great interest. Hence the present study was conducted to evaluate the anti-tumor activity of Mercaptopurine in combination with pepper extract. 20- Methylcholanthrene a Polycyclic aromatic hydrocarbons was used to induce tumor in albino mice. Haematological and endogenous antioxidant parameters were evaluated in the study. Treatment with Mercaptopurine and in combination with pepper extract significantly restored the altered haematological and antioxidant parameters to normal values. <br />Key words: cancer, bioenhancer, pepper, tumor, Haemoglobin, Lipid peroxidation.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="d7f66e3cf0348076e8cf1b9d9fc4969e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89538157,"asset_id":84557260,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89538157/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84557260"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84557260"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84557260; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84557260]").text(description); $(".js-view-count[data-work-id=84557260]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84557260; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84557260']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84557260, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "d7f66e3cf0348076e8cf1b9d9fc4969e" } } $('.js-work-strip[data-work-id=84557260]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84557260,"title":"ANTI-TUMOR ACTIVITY OF MERCAPTOPURINE IN COMBINATION WITH PEPPER","translated_title":"","metadata":{"doi":"10.5281/zenodo.6985560","abstract":"Cancer is one of the most life-threatening diseases and serious health problem in both developing and developed countries. Many synthetic and chemotherapeutic agents used in cancer therapy are having low bioavailability and involve the risk of life-threatening host toxicity. Modern researchers are increasingly showing interest toward the improvement of bioavailability of a large number of drugs by addition of various herbs with bioenhancing properties. In oral drug delivery system, the co-administration of therapeutic agents with natural compounds possessing absorption improving activities, has also garnered great interest. Hence the present study was conducted to evaluate the anti-tumor activity of Mercaptopurine in combination with pepper extract. 20- Methylcholanthrene a Polycyclic aromatic hydrocarbons was used to induce tumor in albino mice. Haematological and endogenous antioxidant parameters were evaluated in the study. Treatment with Mercaptopurine and in combination with pepper extract significantly restored the altered haematological and antioxidant parameters to normal values. \nKey words: cancer, bioenhancer, pepper, tumor, Haemoglobin, Lipid peroxidation.\n"},"translated_abstract":"Cancer is one of the most life-threatening diseases and serious health problem in both developing and developed countries. Many synthetic and chemotherapeutic agents used in cancer therapy are having low bioavailability and involve the risk of life-threatening host toxicity. Modern researchers are increasingly showing interest toward the improvement of bioavailability of a large number of drugs by addition of various herbs with bioenhancing properties. In oral drug delivery system, the co-administration of therapeutic agents with natural compounds possessing absorption improving activities, has also garnered great interest. Hence the present study was conducted to evaluate the anti-tumor activity of Mercaptopurine in combination with pepper extract. 20- Methylcholanthrene a Polycyclic aromatic hydrocarbons was used to induce tumor in albino mice. Haematological and endogenous antioxidant parameters were evaluated in the study. Treatment with Mercaptopurine and in combination with pepper extract significantly restored the altered haematological and antioxidant parameters to normal values. \nKey words: cancer, bioenhancer, pepper, tumor, Haemoglobin, Lipid peroxidation.\n","internal_url":"https://www.academia.edu/84557260/ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER","translated_internal_url":"","created_at":"2022-08-12T08:55:30.319-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89538157,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89538157/thumbnails/1.jpg","file_name":"13.IAJPS13082022.pdf","download_url":"https://www.academia.edu/attachments/89538157/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89538157/13.IAJPS13082022-libre.pdf?1660322008=\u0026response-content-disposition=attachment%3B+filename%3DANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf\u0026Expires=1732719333\u0026Signature=IU~XpADY-zxuc6cuO2Ez22vgwlCWNcmoSFLQfsK9ORmwQtmfo2PoS5P43ZCTZXnWczfh3iuE7waEky-0Jogez7mRgFyRuD27HJWO0u7zoTNPmEgFFR62~rUloY2otWBgvnxrgEl0oDVMkozZmIYnqJSVYRz4wTFMNl19w4UNgSRThjVpP2svpb6Pgwy~ZyzXW7fZUpNTNJ7gV0d1B0sI5hQlPrTObpBejbo4MHBmw7zlSMH95M-VN673EXUDzWBEpArsqRnASIUzE5OI9~uOOB4w0KTzI3tn6yIGwuyET5tGJOo90r8RXInXeEMQNZeQmM9RgqYqphsZFhFUhaLrKw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN_COMBINATION_WITH_PEPPER","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89538157,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89538157/thumbnails/1.jpg","file_name":"13.IAJPS13082022.pdf","download_url":"https://www.academia.edu/attachments/89538157/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"ANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89538157/13.IAJPS13082022-libre.pdf?1660322008=\u0026response-content-disposition=attachment%3B+filename%3DANTI_TUMOR_ACTIVITY_OF_MERCAPTOPURINE_IN.pdf\u0026Expires=1732719333\u0026Signature=IU~XpADY-zxuc6cuO2Ez22vgwlCWNcmoSFLQfsK9ORmwQtmfo2PoS5P43ZCTZXnWczfh3iuE7waEky-0Jogez7mRgFyRuD27HJWO0u7zoTNPmEgFFR62~rUloY2otWBgvnxrgEl0oDVMkozZmIYnqJSVYRz4wTFMNl19w4UNgSRThjVpP2svpb6Pgwy~ZyzXW7fZUpNTNJ7gV0d1B0sI5hQlPrTObpBejbo4MHBmw7zlSMH95M-VN673EXUDzWBEpArsqRnASIUzE5OI9~uOOB4w0KTzI3tn6yIGwuyET5tGJOo90r8RXInXeEMQNZeQmM9RgqYqphsZFhFUhaLrKw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84491430"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84491430/QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER"><img alt="Research paper thumbnail of QUANTITATIVE EVALUATION OF N-NITROSAMINE IMPURITIES IN TELMISARTAN TABLETS USP 20MG, 40MG AND 80MG BY GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETER" class="work-thumbnail" src="https://attachments.academia-assets.com/89496395/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84491430/QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER">QUANTITATIVE EVALUATION OF N-NITROSAMINE IMPURITIES IN TELMISARTAN TABLETS USP 20MG, 40MG AND 80MG BY GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETER</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitroso...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitrosodiisopropylamine, N-Nitrosoisopropylethylamine, N-Nitrosodibutylamine) in Telmisartan Tablets USP 20 mg, 40 mg and 80 mg by GC-MS/MS. Using column Rtx-5 Amine fused silica capillary column with Base deactivated guard column. The validation of optimized method was carried out in accordance with relevant validation principles. The authenticated procedure was noticed to be specific, precise, linear, accurate and rugged with concentration ranging from limit of quantification (LOQ) to 200% specification level for Nitrosamine Impurities. As per daily dose of Telmisartan Tablets, the specification limits of N-Nitrosodimethylamine is 1.2mcg/gm and other Nitrosamine Impurities is 0.33mcg/gm. In this method the limit of detection for N-Nitrosodimethylamine is 0.12mcg/gm and other Nitrosamine Impurities is 0.033mcg/gm. The established method was productively useful to determine the N-Nitrosamine Impurities in Telmisartan Tablets.<br />Keywords: Gas chromatography coupled with mass spectrometry (GC-MS/MS), Telmisartan tablets USP, Nitrosamine impurities, ICH guideline.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="cac53d0408077fb3a8938823c3a2c880" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89496395,"asset_id":84491430,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89496395/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84491430"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84491430"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84491430; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84491430]").text(description); $(".js-view-count[data-work-id=84491430]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84491430; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84491430']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84491430, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "cac53d0408077fb3a8938823c3a2c880" } } $('.js-work-strip[data-work-id=84491430]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84491430,"title":"QUANTITATIVE EVALUATION OF N-NITROSAMINE IMPURITIES IN TELMISARTAN TABLETS USP 20MG, 40MG AND 80MG BY GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETER","translated_title":"","metadata":{"doi":"10.5281/zenodo.6983632","abstract":"Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitrosodiisopropylamine, N-Nitrosoisopropylethylamine, N-Nitrosodibutylamine) in Telmisartan Tablets USP 20 mg, 40 mg and 80 mg by GC-MS/MS. Using column Rtx-5 Amine fused silica capillary column with Base deactivated guard column. The validation of optimized method was carried out in accordance with relevant validation principles. The authenticated procedure was noticed to be specific, precise, linear, accurate and rugged with concentration ranging from limit of quantification (LOQ) to 200% specification level for Nitrosamine Impurities. As per daily dose of Telmisartan Tablets, the specification limits of N-Nitrosodimethylamine is 1.2mcg/gm and other Nitrosamine Impurities is 0.33mcg/gm. In this method the limit of detection for N-Nitrosodimethylamine is 0.12mcg/gm and other Nitrosamine Impurities is 0.033mcg/gm. The established method was productively useful to determine the N-Nitrosamine Impurities in Telmisartan Tablets.\nKeywords: Gas chromatography coupled with mass spectrometry (GC-MS/MS), Telmisartan tablets USP, Nitrosamine impurities, ICH guideline.\n"},"translated_abstract":"Determination of Nitrosamine Impurities (N-Nitrosodimethylamine, N-Nitrosodiethylamine, N-Nitrosodiisopropylamine, N-Nitrosoisopropylethylamine, N-Nitrosodibutylamine) in Telmisartan Tablets USP 20 mg, 40 mg and 80 mg by GC-MS/MS. Using column Rtx-5 Amine fused silica capillary column with Base deactivated guard column. The validation of optimized method was carried out in accordance with relevant validation principles. The authenticated procedure was noticed to be specific, precise, linear, accurate and rugged with concentration ranging from limit of quantification (LOQ) to 200% specification level for Nitrosamine Impurities. As per daily dose of Telmisartan Tablets, the specification limits of N-Nitrosodimethylamine is 1.2mcg/gm and other Nitrosamine Impurities is 0.33mcg/gm. In this method the limit of detection for N-Nitrosodimethylamine is 0.12mcg/gm and other Nitrosamine Impurities is 0.033mcg/gm. The established method was productively useful to determine the N-Nitrosamine Impurities in Telmisartan Tablets.\nKeywords: Gas chromatography coupled with mass spectrometry (GC-MS/MS), Telmisartan tablets USP, Nitrosamine impurities, ICH guideline.\n","internal_url":"https://www.academia.edu/84491430/QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER","translated_internal_url":"","created_at":"2022-08-11T11:43:35.249-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89496395,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496395/thumbnails/1.jpg","file_name":"12.IAJPS12082022.pdf","download_url":"https://www.academia.edu/attachments/89496395/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496395/12.IAJPS12082022-libre.pdf?1660254587=\u0026response-content-disposition=attachment%3B+filename%3DQUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf\u0026Expires=1732810433\u0026Signature=OJxKSsmaOausOFT3so8yaFRscsPWn3zqWks2n2C5znY8XkqjdPRwsxHVwXT8TRunAaMyWtFO~w8v7CMkjYtrXW~PmedGrqC7TKMguzWmNB9KIuR-hw9B9wBDZOXnk5vK~qM7oQZ1pl2nDNc2kqL79DOcmyX8Jdba3AUGV251EnEiF9QeR9kSvS2Dc4QkKy8p7Ph3Qz4vDTo3IK9MBFQ87rFBP7EqrYA37vE6XnvT7wUpIJOnAUa9Uq-dXgV00ng-3sBuH0hJTY6n-Kk-iSwVrk06gHt6jWbgLygQb7rT93-g4MZsiAr2w4LXvFygi6BMaTRj6NzoZv68Y4FtfsqIHg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE_IMPURITIES_IN_TELMISARTAN_TABLETS_USP_20MG_40MG_AND_80MG_BY_GAS_CHROMATOGRAPHY_COUPLED_WITH_MASS_SPECTROMETER","translated_slug":"","page_count":17,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps","email":"Ui9sMjQ3QkNjOVJOZlpVRmRkQWtnMXZneWZuKytHb3UvYTZ4cVlZTGd0MjFLSXpUZEN6MzVnWHN5bjBZMWtDNC0tWXFUZ2VJZkVsRFJyUE5idTlrYndXUT09--c936f20b4ea3b7da38d39058f4fbbcd44511d9ef"},"attachments":[{"id":89496395,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496395/thumbnails/1.jpg","file_name":"12.IAJPS12082022.pdf","download_url":"https://www.academia.edu/attachments/89496395/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"QUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496395/12.IAJPS12082022-libre.pdf?1660254587=\u0026response-content-disposition=attachment%3B+filename%3DQUANTITATIVE_EVALUATION_OF_N_NITROSAMINE.pdf\u0026Expires=1732810433\u0026Signature=OJxKSsmaOausOFT3so8yaFRscsPWn3zqWks2n2C5znY8XkqjdPRwsxHVwXT8TRunAaMyWtFO~w8v7CMkjYtrXW~PmedGrqC7TKMguzWmNB9KIuR-hw9B9wBDZOXnk5vK~qM7oQZ1pl2nDNc2kqL79DOcmyX8Jdba3AUGV251EnEiF9QeR9kSvS2Dc4QkKy8p7Ph3Qz4vDTo3IK9MBFQ87rFBP7EqrYA37vE6XnvT7wUpIJOnAUa9Uq-dXgV00ng-3sBuH0hJTY6n-Kk-iSwVrk06gHt6jWbgLygQb7rT93-g4MZsiAr2w4LXvFygi6BMaTRj6NzoZv68Y4FtfsqIHg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="84491285"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/84491285/FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS"><img alt="Research paper thumbnail of FRAILTY IS A GOOD INDICATOR OF LENGTH OF HOSPITAL STAY IN PATIENTS SUFFERING FROM BACTERIAL MENINGITIS" class="work-thumbnail" src="https://attachments.academia-assets.com/89496343/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/84491285/FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS">FRAILTY IS A GOOD INDICATOR OF LENGTH OF HOSPITAL STAY IN PATIENTS SUFFERING FROM BACTERIAL MENINGITIS</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Purpose: The purpose of the study is to analyze the effect of frailty index on the length of hos...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Purpose:  The purpose of the study is to analyze the effect of frailty index on the length of hospital stay.<br />Method:  After approval from Hospital Ethical committee data was taken from the previous records (hospital database) of patients who were admitted to Leady Reading Hospital, Peshawar for bacterial meningitis. The data was extracted from 2018 to 2021. SPSS 20 version was used for the data analysis.<br />Results:  Among 204 (62.2%) less frail patients, 188 patients (92.15%) had a hospital stay of 0-7 days and 16 patients (7.84%) had a hospital stay of 8-14 days. While in 124 severely frail patients(37.8%), 11 patients (8.9%) had a hospital stay of 0-7 days, 106 patients (85.5%) had a hospital stay of 8-14 days and 7 patients (5.6%) had a stay of greater than 14 days.<br />Conclusion:  We found that severely frail patients (mFI ≥3) had longer hospital stay compared to less frail patient (mFI≤2). This study demonstrated that frailty, not the age, is the independent indicator of poor clinical outcomes and length of hospital stay.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bcd2fcbc1d230c8faeb2a6158f249d14" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":89496343,"asset_id":84491285,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/89496343/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="84491285"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="84491285"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 84491285; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=84491285]").text(description); $(".js-view-count[data-work-id=84491285]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 84491285; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='84491285']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 84491285, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "bcd2fcbc1d230c8faeb2a6158f249d14" } } $('.js-work-strip[data-work-id=84491285]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":84491285,"title":"FRAILTY IS A GOOD INDICATOR OF LENGTH OF HOSPITAL STAY IN PATIENTS SUFFERING FROM BACTERIAL MENINGITIS","translated_title":"","metadata":{"doi":"10.5281/zenodo.6983618","abstract":"Purpose: The purpose of the study is to analyze the effect of frailty index on the length of hospital stay.\nMethod: After approval from Hospital Ethical committee data was taken from the previous records (hospital database) of patients who were admitted to Leady Reading Hospital, Peshawar for bacterial meningitis. The data was extracted from 2018 to 2021. SPSS 20 version was used for the data analysis.\nResults: Among 204 (62.2%) less frail patients, 188 patients (92.15%) had a hospital stay of 0-7 days and 16 patients (7.84%) had a hospital stay of 8-14 days. While in 124 severely frail patients(37.8%), 11 patients (8.9%) had a hospital stay of 0-7 days, 106 patients (85.5%) had a hospital stay of 8-14 days and 7 patients (5.6%) had a stay of greater than 14 days.\nConclusion: We found that severely frail patients (mFI ≥3) had longer hospital stay compared to less frail patient (mFI≤2). This study demonstrated that frailty, not the age, is the independent indicator of poor clinical outcomes and length of hospital stay.\n"},"translated_abstract":"Purpose: The purpose of the study is to analyze the effect of frailty index on the length of hospital stay.\nMethod: After approval from Hospital Ethical committee data was taken from the previous records (hospital database) of patients who were admitted to Leady Reading Hospital, Peshawar for bacterial meningitis. The data was extracted from 2018 to 2021. SPSS 20 version was used for the data analysis.\nResults: Among 204 (62.2%) less frail patients, 188 patients (92.15%) had a hospital stay of 0-7 days and 16 patients (7.84%) had a hospital stay of 8-14 days. While in 124 severely frail patients(37.8%), 11 patients (8.9%) had a hospital stay of 0-7 days, 106 patients (85.5%) had a hospital stay of 8-14 days and 7 patients (5.6%) had a stay of greater than 14 days.\nConclusion: We found that severely frail patients (mFI ≥3) had longer hospital stay compared to less frail patient (mFI≤2). This study demonstrated that frailty, not the age, is the independent indicator of poor clinical outcomes and length of hospital stay.\n","internal_url":"https://www.academia.edu/84491285/FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS","translated_internal_url":"","created_at":"2022-08-11T11:41:20.043-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":15402473,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":89496343,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496343/thumbnails/1.jpg","file_name":"11.IAJPS11082022.pdf","download_url":"https://www.academia.edu/attachments/89496343/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496343/11.IAJPS11082022-libre.pdf?1660254582=\u0026response-content-disposition=attachment%3B+filename%3DFRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf\u0026Expires=1732719333\u0026Signature=IveaHWrUp2l9TyJfwO9WnTM3s0HYULqvzjr5PI3RyxXb~l~pixqf6~Xfa9vgXFxgTEfhUBTTlIHXpUN2gGzwpu1UsIRMF2FZ9ZWIWQjpLpGuZRup52holKLxDyB9h94rEnbBxNcMq-x5u~QnoVf1jBpixDNLzRA4O3LLE1GeM7GCNNKGHJGAXqDI9ZQp2J40oNv~dP~01JDSRSmKj02WWWb1nfnFCnr8z0JR9BWK8cMmDxFQ5xMk5yTebabaLUq~9Rjqxo-40P2P~HFfLk7uXuaTGBJOxbxjBBlf--jXJ3I2P2~omVaAxdszgbY8Ty53ra6EJFON~xSGUOwcXNfiLA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF_HOSPITAL_STAY_IN_PATIENTS_SUFFERING_FROM_BACTERIAL_MENINGITIS","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":15402473,"first_name":"Editor","middle_initials":null,"last_name":"iajps","page_name":"Editoriajps","domain_name":"nagajunauniversity","created_at":"2014-08-19T16:52:49.937-07:00","display_name":"Editor iajps","url":"https://nagajunauniversity.academia.edu/Editoriajps"},"attachments":[{"id":89496343,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/89496343/thumbnails/1.jpg","file_name":"11.IAJPS11082022.pdf","download_url":"https://www.academia.edu/attachments/89496343/download_file?st=MTczMjgwOTE3NSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"FRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/89496343/11.IAJPS11082022-libre.pdf?1660254582=\u0026response-content-disposition=attachment%3B+filename%3DFRAILTY_IS_A_GOOD_INDICATOR_OF_LENGTH_OF.pdf\u0026Expires=1732719333\u0026Signature=IveaHWrUp2l9TyJfwO9WnTM3s0HYULqvzjr5PI3RyxXb~l~pixqf6~Xfa9vgXFxgTEfhUBTTlIHXpUN2gGzwpu1UsIRMF2FZ9ZWIWQjpLpGuZRup52holKLxDyB9h94rEnbBxNcMq-x5u~QnoVf1jBpixDNLzRA4O3LLE1GeM7GCNNKGHJGAXqDI9ZQp2J40oNv~dP~01JDSRSmKj02WWWb1nfnFCnr8z0JR9BWK8cMmDxFQ5xMk5yTebabaLUq~9Rjqxo-40P2P~HFfLk7uXuaTGBJOxbxjBBlf--jXJ3I2P2~omVaAxdszgbY8Ty53ra6EJFON~xSGUOwcXNfiLA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":586,"name":"Health Sciences","url":"https://www.academia.edu/Documents/in/Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); 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