Obesity's Impact on Metabolic Health and Effective Intervent

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This review examines the pathophysiological mechanisms of obesity, including genetic predisposition, hormonal imbalances, inflammation, and gut microbiota changes, and their role in metabolic dysfunction. It also addresses the concepts of "Metabolically Healthy Obesity" (MHO) and "metabolically unhealthy normal weight" (MUHW), highlighting obesity's complexity beyond BMI. Key risk factors such as sedentary lifestyles, poor diets, psychosocial issues, and socioeconomic status are explored. Effective prevention and management strategies include lifestyle changes, pharmacotherapy, bariatric surgery, and public health initiatives. Future research should focus on personalized medicine, novel treatments, and understanding the gut microbiome and epigenetics."> <meta name="citation_abstract_html_url" content="https://japanese.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html"> </head> <body> <header>  <div class="bg-1"> <div class="container-fluid py-1"> <div class="row justify-content-between align-items-center"> <div class="col-sm-auto"> <a href="https://japanese.iomcworld.com/" title="IOMC"><img src="/assets/img/IOMC-logo-white.svg" alt="jdm" height="50" alt="IOMC"></a> </div> <div class="col-sm-auto"> <nav class="nav"> <a class="nav-link white"><i class="fa fa-whatsapp"></i> +32(800) 709-48 </a> <a href="mailto:submissions@iomcworld.com" class="nav-link white"><i class="fas fa-envelope-square"></i> submissions@iomcworld.com</a> <a href="https://longdom.org/submissions/diabetes-metabolism.html" title="" class="btn bg-yellow-100">原稿を提出する</a>  <div class="nav-item dropdown multi_lang j_multi_lang"> <a class="nav-link dropdown-toggle" href="#" id="multi_lang" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">Language</a> <div class="dropdown-menu" aria-labelledby=""> <a class="dropdown-item" href="https://www.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="English"> <img src="https://www.longdom.org/admin/flags/usa.png">English </a> <a class="dropdown-item" href="https://spanish.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Spanish"> <img src="https://www.longdom.org/admin/flags/spain.png">Spanish </a> <a class="dropdown-item" href="https://chinese.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Chinese"> <img src="https://www.longdom.org/admin/flags/china.png">Chinese </a> <a class="dropdown-item" href="https://russian.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Russian"> <img src="https://www.longdom.org/admin/flags/russia.png">Russian </a> <a class="dropdown-item" href="https://german.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="German"> <img src="https://www.longdom.org/admin/flags/germany.png">German </a> <a class="dropdown-item" href="https://french.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="French"> <img src="https://www.longdom.org/admin/flags/france.png">French </a> <a class="dropdown-item" href="https://portuguese.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Portuguese"> <img src="https://www.longdom.org/admin/flags/portugal.png">Portuguese </a> <a class="dropdown-item" href="https://hindi.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Hindi"> <img src="https://www.longdom.org/admin/flags/india.png">Hindi </a> <a class="dropdown-item" href="https://telugu.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Telugu"> <img src="https://www.longdom.org/admin/flags/india.png">Telugu </a> <a class="dropdown-item" href="https://tamil.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html" title="Tamil"> <img src="https://www.longdom.org/admin/flags/india.png">Tamil </a> </div> </div>  </nav> </div> </div> </div> </div>  <div class="py-3"> <div class="container-fluid"> <div class="row align-items-center justify-content-between"> <div class="col-12 col-sm-auto"> <h1 class="rockwell fweight-600 mb-0">糖尿病と代謝のジャーナル</h1> <span class="float-right">ISSN - 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This review examines the pathophysiological mechanisms of obesity, including genetic predisposition, hormonal imbalances, inflammation, and gut microbiota changes, and their role in metabolic dysfunction. It also addresses the concepts of "Metabolically Healthy Obesity" (MHO) and "metabolically unhealthy normal weight" (MUHW), highlighting obesity's complexity beyond BMI. Key risk factors such as sedentary lifestyles, poor diets, psychosocial issues, and socioeconomic status are explored. Effective prevention and management strategies include lifestyle changes, pharmacotherapy, bariatric surgery, and public health initiatives. Future research should focus on personalized medicine, novel treatments, and understanding the gut microbiome and epigenetics.</p> </p> <div class="alert alert-info text-left"><b>免責事項:</b> この要約は人工知能ツールを使用して翻訳されており、まだレビューまたは確認されていません</div> <div class="nav social-icons"> <a class="nav-link w-auto">この記事をシェアする</a> <a title="" target="_blank" href="https://www.facebook.com/sharer.php?u=https://japanese.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="" target="_blank" href="https://twitter.com/share?url=https://japanese.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://japanese.iomcworld.com/abstract/obesitys-impact-on-metabolic-health-and-effective-interventions-130983.html"><i 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Obesity's Impact on Metabolic Health and Effective Intervent | 130983