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Conesina - Wikipedia, la enciclopedia libre
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<li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_es.wikipedia.org&uselang=es" class=""><span>Donaciones</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Especial:Crear_una_cuenta&returnto=Conesina" title="Te recomendamos crear una cuenta e iniciar sesión; sin embargo, no es obligatorio" class=""><span>Crear una cuenta</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Especial:Entrar&returnto=Conesina" title="Te recomendamos iniciar sesión, aunque no es obligatorio [o]" accesskey="o" class=""><span>Acceder</span></a> </li> </ul> </div> </div> </div> <div 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id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Páginas para editores desconectados <a href="/wiki/Ayuda:Introducci%C3%B3n" aria-label="Obtenga más información sobre editar"><span>más información</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Especial:MisContribuciones" title="Una lista de modificaciones hechas desde esta dirección IP [y]" accesskey="y"><span>Contribuciones</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Especial:MiDiscusi%C3%B3n" title="Discusión sobre ediciones hechas desde esta dirección IP [n]" accesskey="n"><span>Discusión</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"><!-- CentralNotice --></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Sitio"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Contenidos" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Contenidos</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">ocultar</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Inicio</div> </a> </li> <li id="toc-Referencias" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Referencias"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Referencias</span> </div> </a> <ul id="toc-Referencias-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Enlaces_externos" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Enlaces_externos"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Enlaces externos</span> </div> </a> <ul id="toc-Enlaces_externos-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contenidos" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Cambiar a la tabla de contenidos" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Cambiar a la tabla de contenidos</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Conesina</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ir a un artículo en otro idioma. Disponible en 6 idiomas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-6" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">6 idiomas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%83%D9%88%D9%86%D9%8A%D8%B3%D9%8A%D9%86" title="كونيسين (árabe)" lang="ar" hreflang="ar" data-title="كونيسين" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Konesin" title="Konesin (checo)" lang="cs" hreflang="cs" data-title="Konesin" data-language-autonym="Čeština" data-language-local-name="checo" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Conessine" title="Conessine (inglés)" lang="en" hreflang="en" data-title="Conessine" data-language-autonym="English" data-language-local-name="inglés" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Conessine" title="Conessine (francés)" lang="fr" hreflang="fr" data-title="Conessine" data-language-autonym="Français" data-language-local-name="francés" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Konesin" title="Konesin (serbocroata)" lang="sh" hreflang="sh" data-title="Konesin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbocroata" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Konesin" title="Konesin (serbio)" lang="sr" hreflang="sr" data-title="Konesin" data-language-autonym="Српски / srpski" data-language-local-name="serbio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q5159518#sitelinks-wikipedia" title="Editar enlaces interlingüísticos" class="wbc-editpage">Editar enlaces</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espacios de 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title="Editar esta página [e]" accesskey="e"><span>Editar</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Conesina&action=history" title="Versiones anteriores de esta página [h]" accesskey="h"><span>Ver historial</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Página de herramientas"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Herramientas" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Herramientas</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Herramientas</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">ocultar</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Más opciones" > <div class="vector-menu-heading"> Acciones </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Conesina"><span>Leer</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Conesina&action=edit" title="Editar esta página [e]" accesskey="e"><span>Editar</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Conesina&action=history"><span>Ver historial</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> General </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Especial:LoQueEnlazaAqu%C3%AD/Conesina" title="Lista de todas las páginas de la wiki que enlazan aquí [j]" accesskey="j"><span>Lo que enlaza aquí</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Especial:CambiosEnEnlazadas/Conesina" rel="nofollow" title="Cambios recientes en las páginas que enlazan con esta [k]" accesskey="k"><span>Cambios en enlazadas</span></a></li><li id="t-upload" class="mw-list-item"><a href="//commons.wikimedia.org/wiki/Special:UploadWizard?uselang=es" title="Subir archivos [u]" accesskey="u"><span>Subir archivo</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Especial:P%C3%A1ginasEspeciales" title="Lista de todas las páginas especiales [q]" accesskey="q"><span>Páginas especiales</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Conesina&oldid=151339260" title="Enlace permanente a esta versión de la página"><span>Enlace permanente</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Conesina&action=info" title="Más información sobre esta página"><span>Información de la página</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Especial:Citar&page=Conesina&id=151339260&wpFormIdentifier=titleform" title="Información sobre cómo citar esta página"><span>Citar esta página</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Especial:Acortador_de_URL&url=https%3A%2F%2Fes.wikipedia.org%2Fwiki%2FConesina"><span>Obtener URL acortado</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Especial:QrCode&url=https%3A%2F%2Fes.wikipedia.org%2Fwiki%2FConesina"><span>Descargar código QR</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Imprimir/exportar </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Especial:Libro&bookcmd=book_creator&referer=Conesina"><span>Crear un libro</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Especial:DownloadAsPdf&page=Conesina&action=show-download-screen"><span>Descargar como PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Conesina&printable=yes" title="Versión imprimible de esta página [p]" accesskey="p"><span>Versión para imprimir</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> En otros proyectos </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Conessine" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q5159518" title="Enlace al elemento conectado del repositorio de datos [g]" accesskey="g"><span>Elemento de Wikidata</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Página de herramientas"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Apariencia"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Apariencia</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">ocultar</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">De Wikipedia, la enciclopedia libre</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="es" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r157776694">.mw-parser-output .infobox .imagen{max-width:100%;margin:0 auto}.mw-parser-output .infobox .imagen img{max-width:100%;height:auto}.mw-parser-output .infobox .mw-kartographer-container .thumbinner,.mw-parser-output .infobox .mw-kartographer-map{box-sizing:border-box;width:100%!important}body.skin-timeless .mw-parser-output .infobox .imagen a.image>img{max-width:100%!important;height:auto!important}</style><table class="infobox" style="width:22.7em; line-height: 1.4em; text-align:left; padding:.23em;"><tbody><tr><th colspan="3" class="cabecera química" style="text-align:center;background-color:#F3E5AB;color:inherit;"><div style="float:right; padding:.1em;" class="noprint"></div><div style="float:left; padding-left:1em" class="noprint"> </div>Conesina</th></tr><tr><td colspan="3" class="imagen" style="text-align:center;"> <span typeof="mw:File"><a href="/wiki/Archivo:Conessine.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Conessine.svg/320px-Conessine.svg.png" decoding="async" width="320" height="261" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Conessine.svg/480px-Conessine.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/39/Conessine.svg/640px-Conessine.svg.png 2x" data-file-width="512" data-file-height="418" /></a></span></td></tr><tr><th colspan="3" style="text-align:center;background-color: #F3E5AB;;"><a href="/wiki/Uni%C3%B3n_Internacional_de_Qu%C3%ADmica_Pura_y_Aplicada" title="Unión Internacional de Química Pura y Aplicada">Nombre IUPAC</a></th></tr><tr><td colspan="3" style="text-align:center;"> (3<i>S</i>,3a<i>S</i>,5a<i>S</i>,5b<i>R</i>,9<i>S</i>,11a<i>R</i>,11b<i>S</i>,13a<i>R</i>)-<i>N</i>,<i>N</i>,2,3,11a-Pentametil-2,3,3a,4,5,5a,5b,6,8,9,10,11,11a,11b,12,13-hexadecahidro-1<i>H</i>-nafto[2′,1′:4,5]indeno[1,7a-<i>c</i>]pirrol-9-amina</td></tr><tr><th colspan="3" style="text-align:center;background-color: #F3E5AB;;">General</th></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;">Otros nombres</th><td colspan="2"> Neriina; Roquesina; Wrightina; Conesinum; (3β)-<i>N</i>,<i>N</i>-Dimetil-con-5-enin-3-amina</td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/F%C3%B3rmula_estructural" title="Fórmula estructural">Fórmula estructural</a></th><td colspan="2"> <span typeof="mw:File"><a href="/wiki/Archivo:Conessine.png" class="mw-file-description" title="Imagen de la estructura"><img alt="Imagen de la estructura" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/Conessine.png/110px-Conessine.png" decoding="async" width="110" height="91" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/Conessine.png/165px-Conessine.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/61/Conessine.png/220px-Conessine.png 2x" data-file-width="480" data-file-height="396" /></a></span></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/F%C3%B3rmula_molecular" title="Fórmula molecular">Fórmula molecular</a></th><td colspan="2"> <a href="/wiki/Carbono" title="Carbono"><span style="color: rgb(000,000,000); font-weight: bold;">C</span></a><sub>24</sub><a href="/wiki/Hidr%C3%B3geno" title="Hidrógeno"><span style="color: rgb(154,154,154); font-weight: bold;">H</span></a><sub>40</sub><a href="/wiki/Nitr%C3%B3geno" title="Nitrógeno"><span style="color: rgb(000,000,255); font-weight: bold;">N</span></a><sub>2</sub><sup> </sup></td></tr><tr><th colspan="3" style="text-align:center;background-color: #F3E5AB;;">Identificadores</th></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/N%C3%BAmero_CAS" class="mw-redirect" title="Número CAS">Número CAS</a></th><td colspan="2"> 546-06-5<sup id="cite_ref-1" class="reference separada"><a href="#cite_note-1"><span class="corchete-llamada">[</span>1<span class="corchete-llamada">]</span></a></sup>​</td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td colspan="2"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/chebi/searchId.do?chebiId=27965">27965</a></span></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td colspan="2"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/191703">191703</a></span></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td colspan="2"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.chemspider.com/389885">389885</a></span></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/PubChem" title="PubChem">PubChem</a></th><td colspan="2"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=441082">441082</a></span></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/UNII" class="mw-redirect" title="UNII">UNII</a></th><td colspan="2"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=EZ38J9BBDF">EZ38J9BBDF</a></span></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td colspan="2"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.kegg.jp/entry/C06545">C06545</a></span></td></tr><tr><td colspan="3" style="text-align:center;"> <div class="mw-collapsible mw-collapsed" style="font-size:95%;border:none; padding: 0;"> <div style="width:100%; font-weight:bold" align="left"><a href="/wiki/SMILES" title="SMILES">SMILES</a></div><div class="mw-collapsible-content" style="text-align:left;">C[C@H]1[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)N(C)C)C)CN1C</div> </div></td></tr><tr><td colspan="3" style="text-align:center;"> <div class="mw-collapsible mw-collapsed" style="font-size:95%;border:none; padding: 0;"> <div style="width:100%; font-weight:bold" align="left"><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div><div class="mw-collapsible-content" style="text-align:left;">InChI=<span class="reflink plainlinks nourlexpansion" style="word-wrap:anywhere;"><a rel="nofollow" class="external text" href="http://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1">1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1</a></span><br />Key: <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22GPLGAQQQNWMVMM-MYAJQUOBSA-N%22">GPLGAQQQNWMVMM-MYAJQUOBSA-N</a></span></div> </div></td></tr><tr><th colspan="3" style="text-align:center;background-color: #F3E5AB;;">Propiedades físicas</th></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/Masa_molar" title="Masa molar">Masa molar</a></th><td colspan="2"> 3566 <a href="/wiki/Gramo" title="Gramo">g</a>/<a href="/wiki/Mol" title="Mol">mol</a></td></tr><tr><th scope="row" style="text-align:left;background-color: #FFFFF0;;"><a href="/wiki/Punto_de_fusi%C3%B3n" title="Punto de fusión">Punto de fusión</a></th><td colspan="2"> 125,5 °C (399 K)</td></tr><tr><td colspan="3" style="text-align:center;background-color: #F8EABA;;"><span style="font-size:smaller">Valores en el <a href="/wiki/Sistema_Internacional_de_Unidades" title="Sistema Internacional de Unidades">SI</a> y en <a href="/wiki/Condiciones_est%C3%A1ndar_(qu%C3%ADmica)" class="mw-redirect" title="Condiciones estándar (química)">condiciones estándar</a><br />(25 <a href="/wiki/Grado_Celsius" title="Grado Celsius">℃</a> y 1 <a href="/wiki/Atm%C3%B3sfera_(unidad)" title="Atmósfera (unidad)">atm</a>), salvo que se indique lo contrario.</span></td></tr><tr><td class="noprint" colspan="3" style="text-align:left;"><div class="plainlinks wikidata-link" style="font-size: 0.85em">[<a href="https://www.wikidata.org/wiki/Q5159518" class="extiw" title="d:Q5159518">editar datos en Wikidata</a>]</div></td></tr></tbody></table> <p>La <b>conesina</b> es un <a href="/wiki/Alcaloide" title="Alcaloide">alcaloide</a> <a href="/wiki/Esteroide" title="Esteroide">esteroide</a> que se encuentra en varias especies de plantas de la familia de las <a href="/wiki/Apocynaceae" title="Apocynaceae">apocináceas</a>, incluidas <i><a href="/wiki/Holarrhena" title="Holarrhena">Holarrhena</a> floribunda</i>,<sup id="cite_ref-2" class="reference separada"><a href="#cite_note-2"><span class="corchete-llamada">[</span>2<span class="corchete-llamada">]</span></a></sup>​ <i><a href="/wiki/Holarrhena_antidysenterica" class="mw-redirect" title="Holarrhena antidysenterica">H. antidysenterica</a></i><sup id="cite_ref-3" class="reference separada"><a href="#cite_note-3"><span class="corchete-llamada">[</span>3<span class="corchete-llamada">]</span></a></sup>​ y <i><a href="/wiki/Funtumia" title="Funtumia">Funtumia</a> elastica</i>.<sup id="cite_ref-4" class="reference separada"><a href="#cite_note-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup>​ Actúa como antagonista de la <a href="/wiki/Histamina" title="Histamina">histamina</a>, selectiva para el s<a href="/wiki/Receptor_de_histamina_H3" title="Receptor de histamina H3">ubtipo H3</a> (con una afinidad de pKi = 8,27; Ki = ~5 nM).<sup id="cite_ref-5" class="reference separada"><a href="#cite_note-5"><span class="corchete-llamada">[</span>5<span class="corchete-llamada">]</span></a></sup>​ También se encontró que tiene largos tiempos de eliminación del <a href="/wiki/Sistema_nervioso_central" title="Sistema nervioso central">Sistema nervioso central</a>, alta penetración de la <a href="/wiki/Barrera_hematoencef%C3%A1lica" title="Barrera hematoencefálica">barrera hematoencefálica</a> y alta afinidad por los receptores adrenérgicos.<sup id="cite_ref-6" class="reference separada"><a href="#cite_note-6"><span class="corchete-llamada">[</span>6<span class="corchete-llamada">]</span></a></sup>​ </p> <div class="mw-heading mw-heading2"><h2 id="Referencias">Referencias</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Conesina&action=edit&section=1" title="Editar sección: Referencias"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="listaref" style="list-style-type: decimal;"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://webbook.nist.gov/cgi/cbook.cgi?ID=546-06-5">Número CAS</a></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text"><span id="CITAREFDuezChamartLejolyHanocq1987" class="citation publicación">Duez, P; Chamart, S; Lejoly, J; Hanocq, M; Zeba, B; Sawadogo, M; Guissou, P; Molle, L (1987). «Changes in conessine in stem bark of Holarrhena floribunda in Burkina Faso». <i>Annales pharmaceutiques françaises</i> <b>45</b> (4): 307-13. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/3445993">3445993</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AConesina&rft.atitle=Changes+in+conessine+in+stem+bark+of+Holarrhena+floribunda+in+Burkina+Faso&rft.au=Chamart%2C+S&rft.au=Duez%2C+P&rft.au=Guissou%2C+P&rft.au=Hanocq%2C+M&rft.au=Lejoly%2C+J&rft.au=Molle%2C+L&rft.au=Sawadogo%2C+M&rft.au=Zeba%2C+B&rft.aufirst=P&rft.aulast=Duez&rft.date=1987&rft.genre=article&rft.issue=4&rft.jtitle=Annales+pharmaceutiques+fran%C3%A7aises&rft.pages=307-13&rft.volume=45&rft_id=info%3Apmid%2F3445993&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><span id="CITAREFKumarSinghBhandariGupta2007" class="citation publicación">Kumar, N; Singh, B; Bhandari, P; Gupta, A. P.; Kaul, V. K. (2007). «Steroidal alkaloids from Holarrhena antidysenterica (L.) WALL». <i>Chemical & Pharmaceutical Bulletin</i> <b>55</b> (6): 912-4. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17541193">17541193</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1248%2Fcpb.55.912">10.1248/cpb.55.912</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AConesina&rft.atitle=Steroidal+alkaloids+from+Holarrhena+antidysenterica+%28L.%29+WALL&rft.au=Bhandari%2C+P&rft.au=Gupta%2C+A.+P.&rft.au=Kaul%2C+V.+K.&rft.au=Kumar%2C+N&rft.au=Singh%2C+B&rft.aufirst=N&rft.aulast=Kumar&rft.date=2007&rft.genre=article&rft.issue=6&rft.jtitle=Chemical+%26+Pharmaceutical+Bulletin&rft.pages=912-4&rft.volume=55&rft_id=info%3Adoi%2F10.1248%2Fcpb.55.912&rft_id=info%3Apmid%2F17541193&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><span id="CITAREFZirihiGrellierGuédé-GuinaBodo2005" class="citation publicación">Zirihi, G. N.; Grellier, P; Guédé-Guina, F; Bodo, B; Mambu, L (2005). «Isolation, characterization and antiplasmodial activity of steroidal alkaloids from Funtumia elastica (Preuss) Stapf». <i>Bioorganic & Medicinal Chemistry Letters</i> <b>15</b> (10): 2637-40. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15863333">15863333</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.bmcl.2005.03.021">10.1016/j.bmcl.2005.03.021</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AConesina&rft.atitle=Isolation%2C+characterization+and+antiplasmodial+activity+of+steroidal+alkaloids+from+Funtumia+elastica+%28Preuss%29+Stapf&rft.au=Bodo%2C+B&rft.au=Grellier%2C+P&rft.au=Gu%C3%A9d%C3%A9-Guina%2C+F&rft.au=Mambu%2C+L&rft.au=Zirihi%2C+G.+N.&rft.aufirst=G.+N.&rft.aulast=Zirihi&rft.date=2005&rft.genre=article&rft.issue=10&rft.jtitle=Bioorganic+%26+Medicinal+Chemistry+Letters&rft.pages=2637-40&rft.volume=15&rft_id=info%3Adoi%2F10.1016%2Fj.bmcl.2005.03.021&rft_id=info%3Apmid%2F15863333&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><span id="CITAREFSantoraCovelHayashiHofilena2008" class="citation publicación">Santora, V. J.; Covel, J. A.; Hayashi, R; Hofilena, B. J.; Ibarra, J. B.; Pulley, M. D.; Weinhouse, M. I.; Sengupta, D; Duffield, J. J.; Semple, G; Webb, R. R.; Sage, C; Ren, A; Pereira, G; Knudsen, J; Edwards, J. E.; Suarez, M; Frazer, J; Thomsen, W; Hauser, E; Whelan, K; Grottick, A. J. (2008). «A new family of H3 receptor antagonists based on the natural product Conessine». <i>Bioorganic & Medicinal Chemistry Letters</i> <b>18</b> (4): 1490-4. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18194865">18194865</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.bmcl.2007.12.059">10.1016/j.bmcl.2007.12.059</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AConesina&rft.atitle=A+new+family+of+H3+receptor+antagonists+based+on+the+natural+product+Conessine&rft.au=Covel%2C+J.+A.&rft.au=Duffield%2C+J.+J.&rft.au=Edwards%2C+J.+E.&rft.au=Frazer%2C+J&rft.au=Grottick%2C+A.+J.&rft.au=Hauser%2C+E&rft.au=Hayashi%2C+R&rft.au=Hofilena%2C+B.+J.&rft.au=Ibarra%2C+J.+B.&rft.au=Knudsen%2C+J&rft.au=Pereira%2C+G&rft.au=Pulley%2C+M.+D.&rft.au=Ren%2C+A&rft.au=Sage%2C+C&rft.au=Santora%2C+V.+J.&rft.au=Semple%2C+G&rft.au=Sengupta%2C+D&rft.au=Suarez%2C+M&rft.au=Thomsen%2C+W&rft.au=Webb%2C+R.+R.&rft.au=Weinhouse%2C+M.+I.&rft.au=Whelan%2C+K&rft.aufirst=V.+J.&rft.aulast=Santora&rft.date=2008&rft.genre=article&rft.issue=4&rft.jtitle=Bioorganic+%26+Medicinal+Chemistry+Letters&rft.pages=1490-4&rft.volume=18&rft_id=info%3Adoi%2F10.1016%2Fj.bmcl.2007.12.059&rft_id=info%3Apmid%2F18194865&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><span id="CITAREFZhaoSunBennaniGopalakrishnan2008" class="citation publicación">Zhao, Chen; Sun, Minghua; Bennani, Youssef L.; Gopalakrishnan, Sujatha M.; Witte, David G.; Miller, Thomas R.; Krueger, Kathleen M.; Browman, Kaitlin E.; Thiffault, Christine; Wetter, Jill; Marsh, Kennan C.; Hancock, Arthur A.; Esbenshade, Timothy A.; Cowart, Marlon D. (2008). «The Alkaloid Conessine and Analogues as Potent Histamine H3Receptor Antagonists». <i>Journal of Medicinal Chemistry</i> <b>51</b> (17): 5423-30. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18683917">18683917</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1021%2Fjm8003625">10.1021/jm8003625</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AConesina&rft.atitle=The+Alkaloid+Conessine+and+Analogues+as+Potent+Histamine+H3Receptor+Antagonists&rft.au=Bennani%2C+Youssef+L.&rft.au=Browman%2C+Kaitlin+E.&rft.au=Cowart%2C+Marlon+D.&rft.au=Esbenshade%2C+Timothy+A.&rft.au=Gopalakrishnan%2C+Sujatha+M.&rft.au=Hancock%2C+Arthur+A.&rft.au=Krueger%2C+Kathleen+M.&rft.au=Marsh%2C+Kennan+C.&rft.au=Miller%2C+Thomas+R.&rft.au=Sun%2C+Minghua&rft.au=Thiffault%2C+Christine&rft.au=Wetter%2C+Jill&rft.au=Witte%2C+David+G.&rft.au=Zhao%2C+Chen&rft.aufirst=Chen&rft.aulast=Zhao&rft.date=2008&rft.genre=article&rft.issue=17&rft.jtitle=Journal+of+Medicinal+Chemistry&rft.pages=5423-30&rft.volume=51&rft_id=info%3Adoi%2F10.1021%2Fjm8003625&rft_id=info%3Apmid%2F18683917&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Enlaces_externos">Enlaces externos</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Conesina&action=edit&section=2" title="Editar sección: Enlaces externos"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><span typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span> <a href="/wiki/Wikimedia_Commons" title="Wikimedia Commons">Wikimedia Commons</a> alberga una categoría multimedia sobre <b><a href="https://commons.wikimedia.org/wiki/Category:Conessine" class="extiw" title="commons:Category:Conessine">la conesina</a></b>.</li></ul> <!-- NewPP limit report Parsed by mw‐api‐ext.codfw.main‐7556f8b5dd‐4sfbx Cached time: 20241122225236 Cache expiry: 2592000 Reduced expiry: false Complications: [] CPU time usage: 0.222 seconds Real time usage: 0.448 seconds Preprocessor visited node count: 3172/1000000 Post‐expand include size: 37664/2097152 bytes Template argument size: 3555/2097152 bytes Highest expansion depth: 14/100 Expensive parser function count: 0/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 10414/5000000 bytes Lua time usage: 0.088/10.000 seconds Lua memory usage: 3219227/52428800 bytes Number of Wikibase entities loaded: 1/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 316.522 1 -total 80.84% 255.869 1 Plantilla:Ficha_de_compuesto_químico 79.24% 250.798 1 Plantilla:Ficha 41.04% 129.905 4 Plantilla:Propiedad 16.56% 52.431 1 Plantilla:Listaref 13.95% 44.167 5 Plantilla:Cite_journal 7.15% 22.629 1 Plantilla:Convertir 4.49% 14.222 2 Plantilla:Lista_desplegable 2.47% 7.803 1 Plantilla:Formatnum 1.89% 5.973 1 Plantilla:Reemplazar --> <!-- Saved in parser cache with key eswiki:pcache:9540867:|#|:idhash:canonical and timestamp 20241122225236 and revision id 151339260. 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