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fluid</title> <meta name="description" content="Search results for: synovial fluid"> <meta name="keywords" content="synovial fluid"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="synovial fluid"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 2185</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: synovial fluid</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2185</span> Evaluation of Osteoprotegrin (OPG) and Tumor Necrosis Factor A (TNF-A) Changes in Synovial Fluid and Serum in Dogs with Osteoarthritis; An Experimental Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Behrooz%20Nikahval">Behrooz Nikahval</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Saeed%20Ahrari-Khafi"> Mohammad Saeed Ahrari-Khafi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sakineh%20Behroozpoor"> Sakineh Behroozpoor</a>, <a href="https://publications.waset.org/abstracts/search?q=Saeed%20Nazifi"> Saeed Nazifi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoarthritis (OA) is a progressive and degenerative condition of the articular cartilage and other joints’ structures. It is essential to diagnose this condition as early as possible. The present research was performed to measure the Osteoprotegrin (OPG) and Tumor Necrosis Factor α (TNF-α) in synovial fluid and blood serum of dogs with surgically transected cruciate ligament as a model of OA, to evaluate if measuring of these parameters can be used as a way of early diagnosis of OA. In the present study, four mature, clinically healthy dogs were selected to investigate the effect of experimental OA, on OPG and TNF-α as a way of early detection of OA. OPG and TNF-α were measured in synovial fluid and blood serum on days 0, 14, 28, 90 and 180 after surgical transaction of cranial cruciate ligament in one stifle joint. Statistical analysis of the results showed that there was a significant increase in TNF-α in both synovial fluid and blood serum. OPG showed a decrease two weeks after OA induction. However, it fluctuated afterward. In conclusion, TNF-α could be used in both synovial fluid and blood serum as a way of early detection of OA; however, further research still needs to be conducted on OPG values in OA detection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=osteoarthritis" title="osteoarthritis">osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoprotegrin" title=" osteoprotegrin"> osteoprotegrin</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20necrosis%20factor%20%CE%B1" title=" tumor necrosis factor α"> tumor necrosis factor α</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20fluid" title=" synovial fluid"> synovial fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=serum" title=" serum"> serum</a>, <a href="https://publications.waset.org/abstracts/search?q=dog" title=" dog"> dog</a> </p> <a href="https://publications.waset.org/abstracts/61004/evaluation-of-osteoprotegrin-opg-and-tumor-necrosis-factor-a-tnf-a-changes-in-synovial-fluid-and-serum-in-dogs-with-osteoarthritis-an-experimental-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61004.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">318</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2184</span> Clinical and Structural Differences in Knee Osteoarthritis with/without Synovial Hypertrophy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gi-Young%20Park">Gi-Young Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Dong%20Rak%20Kwon"> Dong Rak Kwon</a>, <a href="https://publications.waset.org/abstracts/search?q=Sung%20Cheol%20Cho"> Sung Cheol Cho</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: The synovium is known to be involved in many pathological characteristic processes. Also, synovitis is common in advanced osteoarthritis. We aimed to evaluate the clinical, radiographic, and ultrasound findings in patients with knee osteoarthritis and to compare the clinical and imaging findings between knee osteoarthritis with and without synovial hypertrophy confirmed by ultrasound. Methods: One hundred knees (54 left, 46 right) in 95 patients (64 women, 31 men; mean age, 65.9 years; range, 43-85 years) with knee osteoarthritis were recruited. The Visual Analogue Scale (VAS) was used to assess the intensity of knee pain. The severity of knee osteoarthritis was classified according to Kellgren and Lawrence's (K-L) grade on a radiograph. Ultrasound examination was performed by a physiatrist who had 24 years of experience in musculoskeletal ultrasound. Ultrasound findings, including the thickness of joint effusion in the suprapatellar pouch, synovial hypertrophy, infrapatellar tendinosis, meniscal tear or extrusion, and Baker cyst, were measured and detected. The thickness of knee joint effusion was measured at the maximal anterior-posterior diameter of fluid collection in the suprapatellar pouch. Synovial hypertrophy was identified as the soft tissue of variable echogenicity, which is poorly compressible and nondisplaceable by compression of an ultrasound transducer. The knees were divided into two groups according to the presence of synovial hypertrophy. The differences in clinical and imaging findings between the two groups were evaluated by independent t-test and chi-square test. Results: Synovial hypertrophy was detected in 48 knees of 100 knees on ultrasound. There were no significant differences in demographic parameters and VAS score except in sex between the two groups (P<0.05). Medial meniscal extrusion and tear were significantly more frequent in knees with synovial hypertrophy than those in knees without synovial hypertrophy. K-L grade and joint effusion thickness were greater in patients with synovial hypertrophy than those in patients without synovial hypertrophy (P<0.05). Conclusion: Synovial hypertrophy in knee osteoarthritis was associated with greater suprapatellar joint effusion and higher K-L grade and maybe a characteristic ultrasound feature of late knee osteoarthritis. These results suggest that synovial hypertrophy on ultrasound can be regarded as a predictor of rapid progression in patients with knee osteoarthritis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=knee%20osteoarthritis" title="knee osteoarthritis">knee osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20hypertrophy" title=" synovial hypertrophy"> synovial hypertrophy</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrasound" title=" ultrasound"> ultrasound</a>, <a href="https://publications.waset.org/abstracts/search?q=K-L%20grade" title=" K-L grade"> K-L grade</a> </p> <a href="https://publications.waset.org/abstracts/165477/clinical-and-structural-differences-in-knee-osteoarthritis-withwithout-synovial-hypertrophy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/165477.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2183</span> Potential Role of IL-1β in Synovial Fluid in Modulating Multiple Joint Tissue Pathologies Leading to Inflammation and Accelerating Cartilage Degeneration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Priya%20Kulkarni">Priya Kulkarni</a>, <a href="https://publications.waset.org/abstracts/search?q=Soumya%20Koppikar"> Soumya Koppikar</a>, <a href="https://publications.waset.org/abstracts/search?q=Datta%20Shinde"> Datta Shinde</a>, <a href="https://publications.waset.org/abstracts/search?q=Shantanu%20Deshpande"> Shantanu Deshpande</a>, <a href="https://publications.waset.org/abstracts/search?q=Narendrakumar%20Wagh"> Narendrakumar Wagh</a>, <a href="https://publications.waset.org/abstracts/search?q=Abhay%20Harsulkar"> Abhay Harsulkar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoarthritis (OA) is associated with multiple and overlapping aetiologies. IL-1β is produced by stressed tissue and known to aggravate disease pathologies. We selected 10 patients with elevated IL-1β in their synovial fluids (SF). We hypothesized IL-1β as nodal-point connecting different pathologies. IL-1β was higher in all meniscal tear (MT) patients perhaps as the earliest response to injury. Since MT above age of 30 leads to OA in less than 5 years, it is attributed that IL-1β modulates OA pathology. Among all bilateral OA patients, an interesting case operated for Total-Knee-Replacement revealed differential cartilage degeneration demonstrating strong association with higher IL-1β. Symptoms like acute-pain, effusion and redness were correlated with higher IL-1β and NO (Nitric-oxide). However, higher IL-1β was also found without typical-inflammation characterized by infiltration of neutrophils and macrophages. Cultured synoviocytes responded to IL-1β by releasing NO. In conclusion, IL-1β in SF acquires central position influencing different OA pathologies and aetiologies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IL-1%CE%B2" title="IL-1β">IL-1β</a>, <a href="https://publications.waset.org/abstracts/search?q=meniscal%20tear" title=" meniscal tear"> meniscal tear</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoarthritis" title=" osteoarthritis"> osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20fluid" title=" synovial fluid"> synovial fluid</a> </p> <a href="https://publications.waset.org/abstracts/6228/potential-role-of-il-1v-in-synovial-fluid-in-modulating-multiple-joint-tissue-pathologies-leading-to-inflammation-and-accelerating-cartilage-degeneration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6228.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">596</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2182</span> Antioxidant Status in Synovial Fluid from Osteoarthritis Patients: A Pilot Study in Indian Demography</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Koppikar">S. Koppikar</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Kulkarni"> P. Kulkarni</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Ingale"> D. Ingale </a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Wagh"> N. Wagh</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Deshpande"> S. Deshpande</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Mahajan"> A. Mahajan</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Harsulkar"> A. Harsulkar </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Crucial role of reactive oxygen species (ROS) in the progression Osteoarthritis (OA) pathogenesis has been endorsed several times though its exact mechanism remains unclear. Oxidative stress is known to instigate classical stress factors such as cytokines, chemokines and ROS, which hampers cartilage remodelling process and ultimately results in worsening the disease. Synovial fluid (SF) is a biological communicator between cartilage and synovium that accumulates redox and biochemical signalling mediators. The present work attempts to measure several oxidative stress markers in the synovial fluid obtained from knee OA patients with varying degree of disease severity. Thirty OA and five Meniscal-tear (MT) patients were graded using Kellgren-Lawrence scale and assessed for Nitric oxide (NO), Nitrate-Nitrite (NN), 2,2-diphenyl-1-picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Potential (FRAP), Catalase (CAT), Superoxide dismutase (SOD) and Malondialdehyde (MDA) levels for comparison. Out of various oxidative markers studied, NO and SOD showed significant difference between moderate and severe OA (p= 0.007 and p= 0.08, respectively), whereas CAT demonstrated significant difference between MT and mild group (p= 0.07). Interestingly, NN revealed statistically positive correlation with OA severity (p= 0.001 and p= 0.003). MDA, a lipid peroxidation by-product was estimated maximum in early OA when compared to MT (p= 0.06). However, FRAP did not show any correlation with OA severity or MT control. NO is an essential bio-regulatory molecule essential for several physiological processes, and inflammatory conditions. However, due to its short life, exact estimation of NO becomes difficult. NO and its measurable stable products are still it is considered as one of the important biomarker of oxidative damage. Levels of NO and nitrite-nitrate in SF of patients with OA indicated its involvement in the disease progression. When SF groups were compared, a significant correlation among moderate, mild and MT groups was established. To summarize, present data illustrated higher levels of NO, SOD, CAT, DPPH and MDA in early OA in comparison with MT, as a control group. NN had emerged as a prognostic bio marker in knee OA patients, which may act as futuristic targets in OA treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title="antioxidant">antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=knee%20osteoarthritis" title=" knee osteoarthritis"> knee osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20stress" title=" oxidative stress"> oxidative stress</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20fluid" title=" synovial fluid"> synovial fluid</a> </p> <a href="https://publications.waset.org/abstracts/21280/antioxidant-status-in-synovial-fluid-from-osteoarthritis-patients-a-pilot-study-in-indian-demography" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21280.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">477</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2181</span> Isolation, Characterization and Myogenic Differentiation of Synovial Mesenchymal Stem Cells</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatma%20Y.%20Meligy">Fatma Y. Meligy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: The objectives of this study aimed to isolate and characterize mesenchymal stem cells (MSCs) derived from synovial membrane. Then to assess the potentiality of myogenic differentiation of these isolated MSCs. Methods: The MSCs were isolated from synovial membrane by digestion method. Three adult rats were used. The 5 -azacytidine was added to the cultured cells for one day. The isolated cells and treated cells are assessed using immunoflouresence, flowcytometry, PCR and real time PCR. Results: The isolated stem cells showed morphological aspect of stem cells they showed strong positivity to CD44 and CD90 in immunoflouresence while in CD34 and CD45 showed negative reaction. The treated cells with 5-azacytidine was shown to have positive reaction for desmin. Flowcytometric analysis showed that synovial MSCs had strong positive percentage for CD44(%98)and CD90 (%97) and low percentage for CD34 & CD45 while the treated cells showed positive percentage for myogenic marker myogenin (85%). As regard the PCR and Real time PCR, the treated cells showed positive reaction to the desmin primer. Conclusion: The adult MSCs were isolated successfully from synovial membrane and characterized with stem cell markers. The isolated cells could be differentiated in vitro into myogenic cells. These differentiated cells could be used in auto-replacement of diseased or traumatized muscle cells as a regenerative therapy for muscle disorders and trauma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mesenchymal%20stem%20cells" title="mesenchymal stem cells">mesenchymal stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20membrane" title=" synovial membrane"> synovial membrane</a>, <a href="https://publications.waset.org/abstracts/search?q=myogenic%20differentiation" title=" myogenic differentiation "> myogenic differentiation </a> </p> <a href="https://publications.waset.org/abstracts/29107/isolation-characterization-and-myogenic-differentiation-of-synovial-mesenchymal-stem-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29107.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">306</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2180</span> Glycosaminoglycan, a Cartilage Erosion Marker in Synovial Fluid of Osteoarthritis Patients Strongly Correlates with WOMAC Function Subscale</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Priya%20Kulkarni">Priya Kulkarni</a>, <a href="https://publications.waset.org/abstracts/search?q=Soumya%20Koppikar"> Soumya Koppikar</a>, <a href="https://publications.waset.org/abstracts/search?q=Narendrakumar%20Wagh"> Narendrakumar Wagh</a>, <a href="https://publications.waset.org/abstracts/search?q=Dhanshri%20Ingle"> Dhanshri Ingle</a>, <a href="https://publications.waset.org/abstracts/search?q=Onkar%20Lande"> Onkar Lande</a>, <a href="https://publications.waset.org/abstracts/search?q=Abhay%20Harsulkar">Abhay Harsulkar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cartilage is an extracellular matrix composed of aggrecan, which imparts it with a great tensile strength, stiffness and resilience. Disruption in cartilage metabolism leading to progressive degeneration is a characteristic feature of Osteoarthritis (OA). The process involves enzymatic depolymerisation of cartilage specific proteoglycan, releasing free glycosaminoglycan (GAG). This released GAG in synovial fluid (SF) of knee joint serves as a direct measure of cartilage loss, however, limited due to its invasive nature. Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used for assessing pain, stiffness and physical-functions in OA patients. The scale is comprised of three subscales namely, pain, stiffness and physical-function, intends to measure patient’s perspective of disease severity as well as efficacy of prescribed treatment. Twenty SF samples obtained from OA patients were analysed for their GAG values in SF using DMMB based assay. LK 1.0 vernacular version was used to attain WOMAC scale. The results were evaluated using SAS University software (Edition 1.0) for statistical significance. All OA patients revealed higher GAG values compared to the control value of 78.4±30.1µg/ml (obtained from our non-OA patients). Average WOMAC calculated was 51.3 while pain, stiffness and function estimated were 9.7, 3.9 and 37.7, respectively. Interestingly, a strong statistical correlation was established between WOMAC function subscale and GAG (p = 0.0102). This subscale is based on day-to-day activities like stair-use, bending, walking, getting in/out of car, rising from bed. However, pain and stiffness subscale did not show correlation with any of the studied markers and endorsed the atypical inflammation in OA pathology. On one side, where knee pain showed poor correlation with GAG, it is often noted that radiography is insensitive to cartilage degenerative changes; thus OA remains undiagnosed for long. Moreover, active cartilage degradation phase remains elusive to both, patient and clinician. Through analysis of large number of OA patients we have established a close association of Kellgren-Lawrence grades and increased cartilage loss. A direct attempt to correlate WOMAC and radiographic progression of OA with various biomarkers has not been attempted so far. We found a good correlation in GAG levels in SF and the function subscale. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cartilage" title="cartilage">cartilage</a>, <a href="https://publications.waset.org/abstracts/search?q=Glycosaminoglycan" title=" Glycosaminoglycan"> Glycosaminoglycan</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20fluid" title=" synovial fluid"> synovial fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=western%20ontario%20and%20McMaster%20Universities%20Arthritis%20Index" title=" western ontario and McMaster Universities Arthritis Index"> western ontario and McMaster Universities Arthritis Index</a> </p> <a href="https://publications.waset.org/abstracts/21197/glycosaminoglycan-a-cartilage-erosion-marker-in-synovial-fluid-of-osteoarthritis-patients-strongly-correlates-with-womac-function-subscale" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21197.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">446</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2179</span> Traumatic Osteoarthritis Induces Mechanical Hyperalgesia through IL-1β/TNF-α-Mediated Upregulation of the Sema4D Gene Expression</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hsiao-Chien%20Tsai">Hsiao-Chien Tsai</a>, <a href="https://publications.waset.org/abstracts/search?q=Yu-Pin%20Chen"> Yu-Pin Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruei-Ming%20Chen"> Ruei-Ming Chen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Osteoarthritis (OA) is characterized by joint destruction and causes chronic disability. One of the prominent symptoms is pain. Alleviating the pain is necessary and urgent for the therapy of OA patients. However, currently, understanding the mechanisms that drive OA-induced pain remains challenging, which hampers the optimistic management of pain in OA patients. Semaphorin 4D (Sema4D) participates in axon guidance pathway and bone remodeling, thus, may play a role in the regulation of pain in OA. In this study, we have established a rat model of OA to find out the mechanisms of OA-induced pain and to deliberate the roles of Sema4D. Methods: Behavioral changes and the pro-inflammatory cytokines (IL-1β, TNF-α, and IL-17) associated with pain were measured during the development of OA. Sema4D expression in cartilage and synovial membrane at 1, 4, and 12 weeks after inducing OA was analyzed. To assess if Sema4D is related to the neurogenesis in OA as an axon repellant, we analyzed the expression of PGP9.5 as well. Results: Synovitis and cartilage degradation were evident histologically during the development of OA. Mechanical hyperalgesia was most severe at week 1, then persisted thereafter. It was associated with stress coping strategies. Similar to the pain behavioral results, levels of IL-1β and TNF-α in synovial lavage fluid were significantly elevated in the OA group at weeks 1 and 4, respectively. Sema4D expression in cartilage and the synovial membrane was also enhanced in the OA group and was correlated with pain and pro-inflammatory cytokines. The marker of neurogenesis, PGP9.5, was also enhanced during the development of OA. Discussion: OA induced mechanical hyperalgesia, which might be through upregulating IL-1β/TNF-α-mediated Sema4D expressions. If anti-Sema4D treatment could reduce OA-induced mechanical hyperalgesia and prevent the subsequent progression of OA needs to be further investigated. Significance: OA can induce mechanical hyperalgesia through upregulation of IL-1β/TNF-α-mediated Sema4D and PGP9.5 expressions. And the upregulation of Sema4D may indicate the severity or active status of OA and OA-induced pain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=traumatic%20osteoarthritis" title="traumatic osteoarthritis">traumatic osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20hyperalgesia" title=" mechanical hyperalgesia"> mechanical hyperalgesia</a>, <a href="https://publications.waset.org/abstracts/search?q=Sema4D" title=" Sema4D"> Sema4D</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammatory%20cytokines" title=" inflammatory cytokines"> inflammatory cytokines</a> </p> <a href="https://publications.waset.org/abstracts/161254/traumatic-osteoarthritis-induces-mechanical-hyperalgesia-through-il-1vtnf-a-mediated-upregulation-of-the-sema4d-gene-expression" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161254.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2178</span> Localisation of Fluorescently Labelled Drug-Free Phospholipid Vesicles to the Cartilage Surface of Rat Synovial Joints</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sam%20Yurdakul">Sam Yurdakul</a>, <a href="https://publications.waset.org/abstracts/search?q=Nick%20Baverstock"> Nick Baverstock</a>, <a href="https://publications.waset.org/abstracts/search?q=Jim%20Mills"> Jim Mills</a> </p> <p class="card-text"><strong>Abstract:</strong></p> TDT 064 (FLEXISEQ®) is a drug-free gel used to treat osteoarthritis (OA)-associated pain and joint stiffness. It contains ultra-deformable phospholipid Sequessome™ vesicles, which can pass through the skin barrier intact. In six randomized OA studies, topical TDT 064 was well tolerated and improved joint pain, physical function and stiffness. In the largest study, these TDT 064-mediated effects were statistically significantly greater than oral placebo and equivalent to celecoxib. To understand the therapeutic effects of TDT 064, we investigated the localisation of the drug-free vesicles within rat synovial joints. TDT 064 containing DiO-labelled Sequessome™ vesicles was applied to the knees of four 6-week-old CD® hairless rats (10 mg/kg/ joint), 2–3 times/day, for 3 days (representing the recommended clinical dose). Eighteen hours later, the animals and one untreated control were sacrificed, and the knee joints isolated, flash frozen and embedded in Acrytol Mounting Media™. Approximately 15 sections (10 µm) from each joint were analysed by fluorescence microscopy. To investigate whether the localisation of DiO fluorescence was associated with intact vesicles, an anti-PEG monoclonal antibody (mAb) was used to detect Tween, a constituent of Sequessome™ vesicles. Sections were visualized at 484 nm (DiO) and 647 nm (anti-PEG mAb) and analysed using inForm 1.4 (Perkin Elmer, Inc.). Significant fluorescence was observed at 484 nm in sections from TDT 064-treated animals. No non-specific fluorescence was observed in control sections. Fluorescence was detected as discrete vesicles on the cartilage surfaces, inside the cartilaginous matrix and within the synovial space. The number of DiO-labelled vesicles in multiple fields of view was consistent and >100 in sections from four different treated knees. DiO and anti-PEG mAb co-localised within the collagenous tissues in four different joint sections. Under higher magnification (40x), vesicles were seen in the intercellular spaces of the synovial joint tissue, but no fluorescence was seen inside cells. These data suggest that the phospholipid vesicles in TDT 064 localize at the surface of the joint cartilage; these vesicles may therefore be supplementing the phospholipid deficiency reported in OA and acting as a biolubricant within the synovial joint. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=joint%20pain" title="joint pain">joint pain</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoarthritis" title=" osteoarthritis"> osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=phospholipid%20vesicles" title=" phospholipid vesicles"> phospholipid vesicles</a>, <a href="https://publications.waset.org/abstracts/search?q=TDT%20064" title=" TDT 064"> TDT 064</a> </p> <a href="https://publications.waset.org/abstracts/22741/localisation-of-fluorescently-labelled-drug-free-phospholipid-vesicles-to-the-cartilage-surface-of-rat-synovial-joints" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22741.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">443</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2177</span> Microfluidic Lab on Chip Platform for the Detection of Arthritis Markers from Synovial Organ on Chip by Miniaturizing Enzyme-Linked ImmunoSorbent Assay Protocols</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Laura%20Boschis">Laura Boschis</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20D.%20Ozzello"> Elena D. Ozzello</a>, <a href="https://publications.waset.org/abstracts/search?q=Enzo%20Mastromatteo"> Enzo Mastromatteo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Point of care diagnostic finds growing interest in medicine and agri-food because of faster intervention and prevention. EliChip is a microfluidic platform to perform Point of Care immunoenzymatic assay based on ready-to-use kits and a portable instrument to manage fluidics and read reliable quantitative results. Thanks to miniaturization, analyses are faster and more sensible than conventional ELISA. EliChip is one of the crucial assets of the Europen-founded Flamingo project for in-line measuring inflammatory markers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lab%20on%20chip" title="lab on chip">lab on chip</a>, <a href="https://publications.waset.org/abstracts/search?q=point%20of%20care" title=" point of care"> point of care</a>, <a href="https://publications.waset.org/abstracts/search?q=immunoenzymatic%20analysis" title=" immunoenzymatic analysis"> immunoenzymatic analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=synovial%20arthritis" title=" synovial arthritis"> synovial arthritis</a> </p> <a href="https://publications.waset.org/abstracts/148406/microfluidic-lab-on-chip-platform-for-the-detection-of-arthritis-markers-from-synovial-organ-on-chip-by-miniaturizing-enzyme-linked-immunosorbent-assay-protocols" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/148406.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">186</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2176</span> The Effect of SIRT1 on NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3) Inflammasome of Osteoarthritis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=So%20Youn%20Park">So Youn Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Yi%20Sle%20Lee"> Yi Sle Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Ki%20Whan%20Hong"> Ki Whan Hong</a>, <a href="https://publications.waset.org/abstracts/search?q=Chi%20Dae%20Kim"> Chi Dae Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The role of metabolism in the pathogenesis of osteoarthritis is an emerging field. Metabolic alterations may be a role in osteoarthritis (OA) pathogenesis, and these changes influence joint destruction via several cytokine. Especially, in OA patients, levels of IL-1β are elevated in the synovial fluid, synovial membrane, subchondral bone, and cartilage. The IL-1β is activated by NLRP3 inflammasomes, and NLRP3 inflammasomes are cytosolic complexes that drive the production of other inflammatory cytokines, including IL-1β. In this study, we examined that SIRT1 suppresses IL-1β through inhibiting NLRP3 inflammasomes and SIRT1 ameliorates osteoarthritis. OA fibroblasts were isolated from synovium of OA patients. IL-1β and NLRP3 were detected in synovium of OA patients by immunohistochemistry. Lipopolysaccharides (LPS) stimulated the expression of active IL-1β mRNA in OA fibroblasts and combination of LPS, and adenosine triphosphate increased more the expression of active IL-1β in OA fibroblasts. The level of IL-1β was measured by western blot and ELISA assay. NLRP3 inflammasomes complex were measured by western blot. SIRT1 did not inhibit expression of NLRP3 inflammasome. So caspase-1, apoptotic speck-like protein containing a caspase recruitment domain (ASC) and NLRP3 protein were expressed in OA fibroblasts. But SIRT1 suppressed activation of IL-1β by inhibiting activity of caspase-1 via NLRP3 inflammasome in OA fibroblasts under LPS plus ATP stimulation. These results suggest that SIRT1 is a modulator of NLRP3 inflammasomes in OA fibroblasts and ameliorate IL-1β, so expression of SIRT1 in OA fibroblast may be a potential strategy for OA inflammation treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=osteoarthritis" title="osteoarthritis">osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammasome" title=" inflammasome"> inflammasome</a>, <a href="https://publications.waset.org/abstracts/search?q=SIRT1" title=" SIRT1"> SIRT1</a>, <a href="https://publications.waset.org/abstracts/search?q=IL-1beta" title=" IL-1beta"> IL-1beta</a> </p> <a href="https://publications.waset.org/abstracts/76630/the-effect-of-sirt1-on-nlrp3-nucleotide-oligomerization-domain-like-receptor-family-pyrin-domain-containing-3-inflammasome-of-osteoarthritis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76630.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">199</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2175</span> Two Years Retrospective Study of Body Fluid Cultures Obtained from Patients in the Intensive Care Unit of General Hospital of Ioannina</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Varsamis">N. Varsamis</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Gerasimou"> M. Gerasimou</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Christodoulou"> P. Christodoulou</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Mantzoukis"> S. Mantzoukis</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Kolliopoulou"> G. Kolliopoulou</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Zotos"> N. Zotos</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: Body fluids (pleural, peritoneal, synovial, pericardial, cerebrospinal) are an important element in the detection of microorganisms. For this reason, it is important to examine them in the Intensive Care Unit (ICU) patients. Material and Method: Body fluids are transported through sterile containers and enriched as soon as possible with Tryptic Soy Broth (TSB). After one day of incubation, the broth is poured into selective media: Blood, Mac Conkey No. 2, Chocolate, Mueller Hinton, Chapman and Saboureaud agar. The above selective media are incubated directly for 2 days. After this period, if any number of microbial colonies are detected, gram staining is performed. After that, the isolated organisms are identified by biochemical techniques in the automated Microscan system (Siemens) and followed by a sensitivity test on the same system using the minimum inhibitory concentration MIC technique. The sensitivity test is verified by Kirby Bauer-based plate test. Results: In 2017 the Laboratory of Microbiology received 60 samples of body fluids from the ICU. More specifically the Microbiology Department received 6 peritoneal fluid specimens, 18 pleural fluid specimens and 36 cerebrospinal fluid specimens. 36 positive cultures were tested. S. epidermidis was identified in 18 specimens, S. haemolyticus in 6, and E. faecium in 12. Conclusions: The results show low detection of microorganisms in body fluid cultures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=body%20fluids" title="body fluids">body fluids</a>, <a href="https://publications.waset.org/abstracts/search?q=culture" title=" culture"> culture</a>, <a href="https://publications.waset.org/abstracts/search?q=intensive%20care%20unit" title=" intensive care unit"> intensive care unit</a>, <a href="https://publications.waset.org/abstracts/search?q=microorganisms" title=" microorganisms"> microorganisms</a> </p> <a href="https://publications.waset.org/abstracts/103213/two-years-retrospective-study-of-body-fluid-cultures-obtained-from-patients-in-the-intensive-care-unit-of-general-hospital-of-ioannina" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/103213.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">202</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2174</span> Numerical Simulation of Fluid Structure Interaction Using Two-Way Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samira%20Laidaoui">Samira Laidaoui</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Djermane"> Mohammed Djermane</a>, <a href="https://publications.waset.org/abstracts/search?q=Nazihe%20Terfaya"> Nazihe Terfaya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The fluid-structure coupling is a natural phenomenon which reflects the effects of two continuums: fluid and structure of different types in the reciprocal action on each other, involving knowledge of elasticity and fluid mechanics. The solution for such problems is based on the relations of continuum mechanics and is mostly solved with numerical methods. It is a computational challenge to solve such problems because of the complex geometries, intricate physics of fluids, and complicated fluid-structure interactions. The way in which the interaction between fluid and solid is described gives the largest opportunity for reducing the computational effort. In this paper, a problem of fluid structure interaction is investigated with two-way coupling method. The formulation Arbitrary Lagrangian-Eulerian (ALE) was used, by considering a dynamic grid, where the solid is described by a Lagrangian formulation and the fluid by a Eulerian formulation. The simulation was made on the ANSYS software. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ALE" title="ALE">ALE</a>, <a href="https://publications.waset.org/abstracts/search?q=coupling" title=" coupling"> coupling</a>, <a href="https://publications.waset.org/abstracts/search?q=FEM" title=" FEM"> FEM</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid-structure" title=" fluid-structure"> fluid-structure</a>, <a href="https://publications.waset.org/abstracts/search?q=interaction" title=" interaction"> interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=one-way%20method" title=" one-way method"> one-way method</a>, <a href="https://publications.waset.org/abstracts/search?q=two-way%20method" title=" two-way method"> two-way method</a> </p> <a href="https://publications.waset.org/abstracts/36752/numerical-simulation-of-fluid-structure-interaction-using-two-way-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/36752.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">678</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2173</span> Herschel-Bulkley Fluid Flow through Narrow Tubes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Santhosh%20Nallapu">Santhosh Nallapu</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Radhakrishnamacharya"> G. Radhakrishnamacharya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A two-fluid model of Herschel-Bulkley fluid flow through tubes of small diameters is studied. It is assumed that the core region consists of Herschel-Bulkley fluid and Newtonian fluid in the peripheral region. The analytical solutions for velocity, flow flux, effective viscosity, core hematocrit and mean hematocrit have been derived and the effects of various relevant parameters on these flow variables have been studied. It has been observed that the effective viscosity and mean hematocrit increase with yield stress, power-law index, hematocrit and tube radius. Further, the core hematocrit decreases with hematocrit and tube radius. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=two-layered%20model" title="two-layered model">two-layered model</a>, <a href="https://publications.waset.org/abstracts/search?q=non-Newtonian%20fluid" title=" non-Newtonian fluid"> non-Newtonian fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=hematocrit" title=" hematocrit"> hematocrit</a>, <a href="https://publications.waset.org/abstracts/search?q=Fahraeus-Lindqvist%20effect" title=" Fahraeus-Lindqvist effect"> Fahraeus-Lindqvist effect</a>, <a href="https://publications.waset.org/abstracts/search?q=plug%20flow" title=" plug flow"> plug flow</a> </p> <a href="https://publications.waset.org/abstracts/18820/herschel-bulkley-fluid-flow-through-narrow-tubes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18820.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">470</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2172</span> Soret-Driven Convection in a Binary Fluid with Coriolis Force</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20H.%20Z.%20Abidin">N. H. Z. Abidin</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20F.%20M.%20Mokhtar"> N. F. M. Mokhtar</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20S.%20A.%20Gani"> S. S. A. Gani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The influence of diffusion of the thermal or known as Soret effect in a heated Binary fluid model with Coriolis force is investigated theoretically. The linear stability analysis is used, and the eigenvalue is obtained using the Galerkin method. The impact of the Soret and Coriolis force on the onset of stationary convection in a system is analysed with respect to various Binary fluid parameters and presented graphically. It is found that an increase of the Soret values, destabilize the Binary fluid layer system. However, elevating the values of the Coriolis force helps to lag the onset of convection in a system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Benard%20convection" title="Benard convection">Benard convection</a>, <a href="https://publications.waset.org/abstracts/search?q=binary%20fluid" title=" binary fluid"> binary fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=Coriolis" title=" Coriolis"> Coriolis</a>, <a href="https://publications.waset.org/abstracts/search?q=Soret" title=" Soret "> Soret </a> </p> <a href="https://publications.waset.org/abstracts/68076/soret-driven-convection-in-a-binary-fluid-with-coriolis-force" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68076.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2171</span> Introduction of the Fluid-Structure Coupling into the Force Analysis Technique</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Oc%C3%A9ane%20Grosset">Océane Grosset</a>, <a href="https://publications.waset.org/abstracts/search?q=Charles%20P%C3%A9zerat"> Charles Pézerat</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Hugh%20Thomas"> Jean-Hugh Thomas</a>, <a href="https://publications.waset.org/abstracts/search?q=Fr%C3%A9d%C3%A9ric%20Ablitzer"> Frédéric Ablitzer</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents a method to take into account the fluid-structure coupling into an inverse method, the Force Analysis Technique (FAT). The FAT method, also called RIFF method (Filtered Windowed Inverse Resolution), allows to identify the force distribution from local vibration field. In order to only identify the external force applied on a structure, it is necessary to quantify the fluid-structure coupling, especially in naval application, where the fluid is heavy. This method can be decomposed in two parts, the first one consists in identifying the fluid-structure coupling and the second one to introduced it in the FAT method to reconstruct the external force. Results of simulations on a plate coupled with a cavity filled with water are presented. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aeroacoustics" title="aeroacoustics">aeroacoustics</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid-structure%20coupling" title=" fluid-structure coupling"> fluid-structure coupling</a>, <a href="https://publications.waset.org/abstracts/search?q=inverse%20methods" title=" inverse methods"> inverse methods</a>, <a href="https://publications.waset.org/abstracts/search?q=naval" title=" naval"> naval</a>, <a href="https://publications.waset.org/abstracts/search?q=turbulent%20flow" title=" turbulent flow"> turbulent flow</a> </p> <a href="https://publications.waset.org/abstracts/58380/introduction-of-the-fluid-structure-coupling-into-the-force-analysis-technique" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58380.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">518</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2170</span> Exploring Unexplored Horizons: Advanced Fluid Mechanics Solutions for Sustainable Energy Technologies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elvira%20S.%20Castillo">Elvira S. Castillo</a>, <a href="https://publications.waset.org/abstracts/search?q=Surupa%20Shaw"> Surupa Shaw</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper explores advanced applications of fluid mechanics in the context of sustainable energy. By examining the integration of fluid dynamics with renewable energy technologies, the research uncovers previously underutilized strategies for improving efficiency. Through theoretical analyses, the study demonstrates how fluid mechanics can be harnessed to optimize renewable energy systems. The findings contribute to expanding knowledge in sustainable energy by offering practical insights and methodologies for future research and technological advancements to address global energy challenges. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fluid%20mechanics" title="fluid mechanics">fluid mechanics</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainable%20energy" title=" sustainable energy"> sustainable energy</a>, <a href="https://publications.waset.org/abstracts/search?q=energy%20efficiency" title=" energy efficiency"> energy efficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=green%20energy" title=" green energy"> green energy</a> </p> <a href="https://publications.waset.org/abstracts/185372/exploring-unexplored-horizons-advanced-fluid-mechanics-solutions-for-sustainable-energy-technologies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185372.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">50</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2169</span> Vibration Analysis of Pendulum in a Viscous Fluid by Analytical Methods</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Arash%20Jafari">Arash Jafari</a>, <a href="https://publications.waset.org/abstracts/search?q=Mehdi%20Taghaddosi"> Mehdi Taghaddosi</a>, <a href="https://publications.waset.org/abstracts/search?q=Azin%20Parvin"> Azin Parvin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, a vibrational differential equation governing on swinging single-degree-of-freedom pendulum in a viscous fluid has been investigated. The damping process is characterized according to two different regimes: at first, damping in stationary viscous fluid, in the second, damping in flowing viscous fluid with constant velocity. Our purpose is to enhance the ability of solving the mentioned nonlinear differential equation with a simple and innovative approach. Comparisons are made between new method and Numerical Method (rkf45). The results show that this method is very effective and simple and can be applied for other nonlinear problems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=oscillating%20systems" title="oscillating systems">oscillating systems</a>, <a href="https://publications.waset.org/abstracts/search?q=angular%20frequency%20and%20damping%20ratio" title=" angular frequency and damping ratio"> angular frequency and damping ratio</a>, <a href="https://publications.waset.org/abstracts/search?q=pendulum%20at%20fluid" title=" pendulum at fluid"> pendulum at fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=locus%20of%20maximum" title=" locus of maximum"> locus of maximum</a> </p> <a href="https://publications.waset.org/abstracts/58354/vibration-analysis-of-pendulum-in-a-viscous-fluid-by-analytical-methods" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58354.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">337</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2168</span> Spillage Prediction Using Fluid-Structure Interaction Simulation with Coupled Eulerian-Lagrangian Technique</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ravi%20Soni">Ravi Soni</a>, <a href="https://publications.waset.org/abstracts/search?q=Irfan%20Pathan"> Irfan Pathan</a>, <a href="https://publications.waset.org/abstracts/search?q=Manish%20Pande"> Manish Pande</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The current product development process needs simultaneous consideration of different physics. The performance of the product needs to be considered under both structural and fluid loads. Examples include ducts and valves where structural behavior affects fluid motion and vice versa. Simulation of fluid-structure interaction involves modeling interaction between moving components and the fluid flow. In these scenarios, it is difficult to calculate the damping provided by fluid flow because of dynamic motions of components and the transient nature of the flow. Abaqus Explicit offers general capabilities for modeling fluid-structure interaction with the Coupled Eulerian-Lagrangian (CEL) method. The Coupled Eulerian-Lagrangian technique has been used to simulate fluid spillage through fuel valves during dynamic closure events. The technique to simulate pressure drops across Eulerian domains has been developed using stagnation pressure. Also, the fluid flow is calculated considering material flow through elements at the outlet section of the valves. The methodology has been verified on Eaton products and shows a good correlation with the test results. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Coupled%20Eulerian-Lagrangian%20Technique" title="Coupled Eulerian-Lagrangian Technique">Coupled Eulerian-Lagrangian Technique</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid%20structure%20interaction" title=" fluid structure interaction"> fluid structure interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=spillage%20prediction" title=" spillage prediction"> spillage prediction</a>, <a href="https://publications.waset.org/abstracts/search?q=stagnation%20pressure" title=" stagnation pressure"> stagnation pressure</a> </p> <a href="https://publications.waset.org/abstracts/56823/spillage-prediction-using-fluid-structure-interaction-simulation-with-coupled-eulerian-lagrangian-technique" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56823.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">379</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2167</span> Magnetohydrodynamic Couette Flow of Fractional Burger’s Fluid in an Annulus</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sani%20Isa">Sani Isa</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20Musa"> Ali Musa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Burgers’ fluid with a fractional derivatives model in an annulus was analyzed. Combining appropriately the basic equations, with the fractionalized fractional Burger’s fluid model allow us to determine the velocity field, temperature and shear stress. The governing partial differential equation was solved using the combine Laplace transformation method and Riemann sum approximation to give velocity field, temperature and shear stress on the fluid flow. The influence of various parameters like fractional parameters, relaxation time and retardation time, are drawn. The results obtained are simulated using Mathcad software and presented graphically. From the graphical results, we observed that the relaxation time and time helps the flow pattern, on the other hand, other material constants resist the fluid flow while fractional parameters effect on fluid flow is opposite to each other. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sani%20isa" title="sani isa">sani isa</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20musaburger%E2%80%99s%20fluid" title=" Ali musaburger’s fluid"> Ali musaburger’s fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=Laplace%20transform" title=" Laplace transform"> Laplace transform</a>, <a href="https://publications.waset.org/abstracts/search?q=fractional%20derivatives" title=" fractional derivatives"> fractional derivatives</a>, <a href="https://publications.waset.org/abstracts/search?q=annulus" title=" annulus"> annulus</a> </p> <a href="https://publications.waset.org/abstracts/190150/magnetohydrodynamic-couette-flow-of-fractional-burgers-fluid-in-an-annulus" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/190150.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">24</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2166</span> Numerical Investigation of Pressure and Velocity Field Contours of Dynamics of Drop Formation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pardeep%20Bishnoi">Pardeep Bishnoi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayank%20Srivastava"> Mayank Srivastava</a>, <a href="https://publications.waset.org/abstracts/search?q=Mrityunjay%20Kumar%20Sinha"> Mrityunjay Kumar Sinha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This article represents the numerical investigation of the pressure and velocity field variation of the dynamics of pendant drop formation through a capillary tube. Numerical simulations are executed using volume of fluid (VOF) method in the computational fluid dynamics (CFD). In this problem, Non Newtonian fluid is considered as dispersed fluid whereas air is considered as a continuous fluid. Pressure contours at various time steps expose that pressure varies nearly hydrostatically at each step of the dynamics of drop formation. A result also shows the pressure variation of the liquid droplet during free fall in the computational domain. The evacuation of the fluid from the necking region is also shown by the contour of the velocity field. The role of surface tension in the Pressure contour of the dynamics of drop formation is also studied. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pressure%20contour" title="pressure contour">pressure contour</a>, <a href="https://publications.waset.org/abstracts/search?q=surface%20tension" title=" surface tension"> surface tension</a>, <a href="https://publications.waset.org/abstracts/search?q=volume%20of%20fluid" title=" volume of fluid"> volume of fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=velocity%20field" title=" velocity field"> velocity field</a> </p> <a href="https://publications.waset.org/abstracts/56670/numerical-investigation-of-pressure-and-velocity-field-contours-of-dynamics-of-drop-formation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56670.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">405</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2165</span> Computational Fluid Dynamics Simulation and Comparison of Flow through Mechanical Heart Valve Using Newtonian and Non-Newtonian Fluid</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=D.%20%C5%A0ediv%C3%BD">D. Šedivý</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Fialov%C3%A1"> S. Fialová</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The main purpose of this study is to show differences between the numerical solution of the flow through the artificial heart valve using Newtonian or non-Newtonian fluid. The simulation was carried out by a commercial computational fluid dynamics (CFD) package based on finite-volume method. An aortic bileaflet heart valve (Sorin Bicarbon) was used as a pattern for model of real heart valve replacement. Computed tomography (CT) was used to gain the accurate parameters of the valve. Data from CT were transferred in the commercial 3D designer, where the model for CFD was made. Carreau rheology model was applied as non-Newtonian fluid. Physiological data of cardiac cycle were used as boundary conditions. Outputs were taken the leaflets excursion from opening to closure and the fluid dynamics through the valve. This study also includes experimental measurement of pressure fields in ambience of valve for verification numerical outputs. Results put in evidence a favorable comparison between the computational solutions of flow through the mechanical heart valve using Newtonian and non-Newtonian fluid. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=computational%20modeling" title="computational modeling">computational modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=dynamic%20mesh" title=" dynamic mesh"> dynamic mesh</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20heart%20valve" title=" mechanical heart valve"> mechanical heart valve</a>, <a href="https://publications.waset.org/abstracts/search?q=non-Newtonian%20fluid" title=" non-Newtonian fluid"> non-Newtonian fluid</a> </p> <a href="https://publications.waset.org/abstracts/70433/computational-fluid-dynamics-simulation-and-comparison-of-flow-through-mechanical-heart-valve-using-newtonian-and-non-newtonian-fluid" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70433.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2164</span> Estimation of Damping Force of Double Ended Shear Mode Magnetorheological Damper Using Computational Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gurubasavaraju%20T.%20M.">Gurubasavaraju T. M.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The magnetorheological (MR) damper could provide variable damping force with respect to the different input magnetic field. The damping force could be estimated through computational analysis using finite element and computational fluid dynamics analysis. The double-ended damper operates without changing the total volume of fluid. In this paper, damping force of double ended damper under different magnetic field is computed. Initially, the magneto-statics analysis carried out to evaluate the magnetic flux density across the fluid flow gap. The respective change in the rheology of the MR fluid is computed by using the experimentally fitted polynomial equation of shear stress versus magnetic field plot of MR fluid. The obtained values are substituted in the Herschel Buckley model to express the non-Newtonian behavior of MR fluid. Later, using computational fluid dynamic (CFD) analysis damping characteristics in terms of force versus velocity and force versus displacement for the respective magnetic field is estimated. The purpose of the present approach is to characterize the preliminary designed MR damper before fabricating. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MR%20fluid" title="MR fluid">MR fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=double%20ended%20MR%20damper" title=" double ended MR damper"> double ended MR damper</a>, <a href="https://publications.waset.org/abstracts/search?q=CFD" title=" CFD"> CFD</a>, <a href="https://publications.waset.org/abstracts/search?q=FEA" title=" FEA "> FEA </a> </p> <a href="https://publications.waset.org/abstracts/98450/estimation-of-damping-force-of-double-ended-shear-mode-magnetorheological-damper-using-computational-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98450.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2163</span> Comparison Analysis of CFD Turbulence Fluid Numerical Study for Quick Coupling</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=JoonHo%20Lee">JoonHo Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=KyoJin%20An"> KyoJin An</a>, <a href="https://publications.waset.org/abstracts/search?q=JunSu%20Kim"> JunSu Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Young-Chul%20Park"> Young-Chul Park</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the fluid flow characteristics and performance numerical study through CFD model of the Non-split quick coupling for flow control in hydraulic system equipment for the aerospace business group focused to predict. In this study, we considered turbulence models for the application of Computational Fluid Dynamics for the CFD model of the Non-split Quick Coupling for aerospace business. In addition to this, the adequacy of the CFD model were verified by comparing with standard value. Based on this analysis, accurate the fluid flow characteristics can be predicted. It is, therefore, the design of the fluid flow characteristic contribute the reliability for the Quick Coupling which is required in industries on the basis of research results. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CFD" title="CFD">CFD</a>, <a href="https://publications.waset.org/abstracts/search?q=FEM" title=" FEM"> FEM</a>, <a href="https://publications.waset.org/abstracts/search?q=quick%20coupling" title=" quick coupling"> quick coupling</a>, <a href="https://publications.waset.org/abstracts/search?q=turbulence" title=" turbulence"> turbulence</a> </p> <a href="https://publications.waset.org/abstracts/31538/comparison-analysis-of-cfd-turbulence-fluid-numerical-study-for-quick-coupling" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31538.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">384</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2162</span> Coupling Concept of Two Parallel Research Codes for Two and Three Dimensional Fluid Structure Interaction Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Luciano%20Garelli">Luciano Garelli</a>, <a href="https://publications.waset.org/abstracts/search?q=Marco%20Schauer"> Marco Schauer</a>, <a href="https://publications.waset.org/abstracts/search?q=Jorge%20D%E2%80%99Elia"> Jorge D’Elia</a>, <a href="https://publications.waset.org/abstracts/search?q=Mario%20A.%20Storti"> Mario A. Storti</a>, <a href="https://publications.waset.org/abstracts/search?q=Sabine%20C.%20Langer"> Sabine C. Langer </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper discuss a coupling strategy of two different software packages to provide fluid structure interaction (FSI) analysis. The basic idea is to combine the advantages of the two codes to create a powerful FSI solver for two and three dimensional analysis. The fluid part is computed by a program called PETSc-FEM, a software developed at Centro de Investigación de Métodos Computacionales (CIMEC). The structural part of the coupled process is computed by the research code elementary Parallel Solver (elPaSo) of the Technische Universität Braunschweig, Institut für Konstruktionstechnik (IK). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=computational%20fluid%20dynamics%20%28CFD%29" title="computational fluid dynamics (CFD)">computational fluid dynamics (CFD)</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid%20structure%20interaction%20%28FSI%29" title=" fluid structure interaction (FSI)"> fluid structure interaction (FSI)</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20method%20%28FEM%29" title=" finite element method (FEM)"> finite element method (FEM)</a>, <a href="https://publications.waset.org/abstracts/search?q=software" title=" software"> software</a> </p> <a href="https://publications.waset.org/abstracts/8546/coupling-concept-of-two-parallel-research-codes-for-two-and-three-dimensional-fluid-structure-interaction-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8546.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">552</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2161</span> Seasonal Heat Stress Effect on Cholesterol, Estradiol and Progesterone during Follicular Development in Egyptian Buffalo</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Heba%20F.%20Hozyen">Heba F. Hozyen</a>, <a href="https://publications.waset.org/abstracts/search?q=Hodallah%20H.%20Ahmed"> Hodallah H. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20I.%20A.%20Shalaby"> S. I. A. Shalaby</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20E.%20S.%20Essawy"> G. E. S. Essawy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biochemical and hormonal changes that occur in both follicular fluid and blood are involved in the control of ovarian physiology. The present study was conducted on follicular fluid and serum samples obtained from 708 buffaloes. Samples were examined for estradiol, progesterone, and cholesterol concentrations in relation to seasonal changes, ovarian follicular size, and stage of estrous cycle. The obtained results revealed that follicular fluid and serum levels of estradiol, progesterone, and cholesterol were significantly lower during summer and autumn when compared to winter and spring seasons. With the increase in follicular size, the follicular fluid levels of progesterone and cholesterol were significantly decreased, while estradiol levels were significantly increased. Estradiol and progesterone levels were significantly higher in follicular fluid than blood, while cholesterol was significantly lower in follicular fluid than serum. In conclusion, the current study threw a light on the hormonal changes in the follicular fluid and blood under the effect of heat stress which could be related to the low fertility of buffalo in the summer. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=buffalo" title="buffalo">buffalo</a>, <a href="https://publications.waset.org/abstracts/search?q=follicular%20fluid" title=" follicular fluid"> follicular fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=folliculogenesis" title=" folliculogenesis"> folliculogenesis</a>, <a href="https://publications.waset.org/abstracts/search?q=seasonal%20changes" title=" seasonal changes"> seasonal changes</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a> </p> <a href="https://publications.waset.org/abstracts/37224/seasonal-heat-stress-effect-on-cholesterol-estradiol-and-progesterone-during-follicular-development-in-egyptian-buffalo" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37224.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">510</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2160</span> Hydrodynamic Analysis with Heat Transfer in Solid Gas Fluidized Bed Reactor for Solar Thermal Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sam%20Rasoulzadeh">Sam Rasoulzadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Atefeh%20Mousavi"> Atefeh Mousavi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Fluidized bed reactors are known as highly exothermic and endothermic according to uniformity in temperature as a safe and effective mean for catalytic reactors. In these reactors, a wide range of catalyst particles can be used and by using a continuous operation proceed to produce in succession. Providing optimal conditions for the operation of these types of reactors will prevent the exorbitant costs necessary to carry out laboratory work. In this regard, a hydrodynamic analysis was carried out with heat transfer in the solid-gas fluidized bed reactor for solar thermal applications. The results showed that in the fluid flow the input of the reactor has a lower temperature than the outlet, and when the fluid is passing from the reactor, the heat transfer happens between cylinder and solar panel and fluid. It increases the fluid temperature in the outlet pump and also the kinetic energy of the fluid has been raised in the outlet areas. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=heat%20transfer" title="heat transfer">heat transfer</a>, <a href="https://publications.waset.org/abstracts/search?q=solar%20reactor" title=" solar reactor"> solar reactor</a>, <a href="https://publications.waset.org/abstracts/search?q=fluidized%20bed%20reactor" title=" fluidized bed reactor"> fluidized bed reactor</a>, <a href="https://publications.waset.org/abstracts/search?q=CFD" title=" CFD"> CFD</a>, <a href="https://publications.waset.org/abstracts/search?q=computational%20fluid%20dynamics" title=" computational fluid dynamics"> computational fluid dynamics</a> </p> <a href="https://publications.waset.org/abstracts/100498/hydrodynamic-analysis-with-heat-transfer-in-solid-gas-fluidized-bed-reactor-for-solar-thermal-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/100498.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">179</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2159</span> Effect of Channel Variation of Two-Dimensional Water Tunnel to Study Fluid Dynamics Phenomenon</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rizka%20Yunita">Rizka Yunita</a>, <a href="https://publications.waset.org/abstracts/search?q=Mas%20Aji%20Rizki%20Wijayanto"> Mas Aji Rizki Wijayanto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Computational fluid dynamics (CFD) is the solution to explain how fluid dynamics behavior. In this work, we obtain the effect of channel width of two-dimensional fluid visualization. Using a horizontal water tunnel and flowing soap film, we got a visualization of continuous film that can be observe a graphical overview of the flow that occurs on a space or field in which the fluid flow. The horizontal water tunnel we used, divided into three parts, expansion area, parallel area that used to test the data, and contraction area. The width of channel is the boundary of parallel area with the originally width of 7.2 cm, and the variation of channel width we observed is about 1 cm and its times. To compute the velocity, vortex shedding, and other physical parameters of fluid, we used the cyclinder circular as an obstacle to create a von Karman vortex in fluid and analyzed that phenomenon by using Particle Imaging Velocimetry (PIV) method and comparing Reynolds number and Strouhal number from the visualization we got. More than width the channel, the film is more turbulent and have a separation zones that occurs of uncontinuous flowing fluid. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=flow%20visualization" title="flow visualization">flow visualization</a>, <a href="https://publications.waset.org/abstracts/search?q=width%20of%20channel" title=" width of channel"> width of channel</a>, <a href="https://publications.waset.org/abstracts/search?q=vortex" title=" vortex"> vortex</a>, <a href="https://publications.waset.org/abstracts/search?q=Reynolds%20number" title=" Reynolds number"> Reynolds number</a>, <a href="https://publications.waset.org/abstracts/search?q=Strouhal%20number" title=" Strouhal number"> Strouhal number</a> </p> <a href="https://publications.waset.org/abstracts/22435/effect-of-channel-variation-of-two-dimensional-water-tunnel-to-study-fluid-dynamics-phenomenon" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22435.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">379</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2158</span> On the Strong Solutions of the Nonlinear Viscous Rotating Stratified Fluid</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Giniatoulline">A. Giniatoulline</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A nonlinear model of the mathematical fluid dynamics which describes the motion of an incompressible viscous rotating fluid in a homogeneous gravitational field is considered. The model is a generalization of the known Navier-Stokes system with the addition of the Coriolis parameter and the equations for changeable density. An explicit algorithm for the solution is constructed, and the proof of the existence and uniqueness theorems for the strong solution of the nonlinear problem is given. For the linear case, the localization and the structure of the spectrum of inner waves are also investigated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Galerkin%20method" title="Galerkin method">Galerkin method</a>, <a href="https://publications.waset.org/abstracts/search?q=Navier-Stokes%20equations" title=" Navier-Stokes equations"> Navier-Stokes equations</a>, <a href="https://publications.waset.org/abstracts/search?q=nonlinear%20partial%20differential%20equations" title=" nonlinear partial differential equations"> nonlinear partial differential equations</a>, <a href="https://publications.waset.org/abstracts/search?q=Sobolev%20spaces" title=" Sobolev spaces"> Sobolev spaces</a>, <a href="https://publications.waset.org/abstracts/search?q=stratified%20fluid" title=" stratified fluid"> stratified fluid</a> </p> <a href="https://publications.waset.org/abstracts/52024/on-the-strong-solutions-of-the-nonlinear-viscous-rotating-stratified-fluid" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52024.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">309</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2157</span> Mathematical Properties of the Viscous Rotating Stratified Fluid Counting with Salinity and Heat Transfer in a Layer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Giniatoulline">A. Giniatoulline</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A model of the mathematical fluid dynamics which describes the motion of a three-dimensional viscous rotating fluid in a homogeneous gravitational field with the consideration of the salinity and heat transfer is considered in a vertical finite layer. The model is a generalization of the linearized Navier-Stokes system with the addition of the Coriolis parameter and the equations for changeable density, salinity, and heat transfer. An explicit solution is constructed and the proof of the existence and uniqueness theorems is given. The localization and the structure of the spectrum of inner waves is also investigated. The results may be used, in particular, for constructing stable numerical algorithms for solutions of the considered models of fluid dynamics of the Atmosphere and the Ocean. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fourier%20transform" title="Fourier transform">Fourier transform</a>, <a href="https://publications.waset.org/abstracts/search?q=generalized%20solutions" title=" generalized solutions"> generalized solutions</a>, <a href="https://publications.waset.org/abstracts/search?q=Navier-Stokes%20equations" title=" Navier-Stokes equations"> Navier-Stokes equations</a>, <a href="https://publications.waset.org/abstracts/search?q=stratified%20fluid" title=" stratified fluid"> stratified fluid</a> </p> <a href="https://publications.waset.org/abstracts/75712/mathematical-properties-of-the-viscous-rotating-stratified-fluid-counting-with-salinity-and-heat-transfer-in-a-layer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/75712.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">255</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2156</span> Entropy Generation of Unsteady Reactive Hydromagnetic Generalized Couette Fluid Flow of a Two-Step Exothermic Chemical Reaction Through a Channel</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rasaq%20Kareem">Rasaq Kareem</a>, <a href="https://publications.waset.org/abstracts/search?q=Jacob%20Gbadeyan"> Jacob Gbadeyan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, analysis of the entropy generation of an unsteady reactive hydromagnetic generalized couette fluid flow of a two-step exothermic chemical reaction through a channel with isothermal wall temperature under the influence of different chemical kinetics namely: Sensitized, Arrhenius and Bimolecular kinetics was investigated. The modelled nonlinear dimensionless equations governing the fluid flow were simplified and solved using the combined Laplace Differential Transform Method (LDTM). The effects of fluid parameters associated with the problem on the fluid temperature, entropy generation rate and Bejan number were discussed and presented through graphs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=couette" title="couette">couette</a>, <a href="https://publications.waset.org/abstracts/search?q=entropy" title=" entropy"> entropy</a>, <a href="https://publications.waset.org/abstracts/search?q=exothermic" title=" exothermic"> exothermic</a>, <a href="https://publications.waset.org/abstracts/search?q=unsteady" title=" unsteady"> unsteady</a> </p> <a href="https://publications.waset.org/abstracts/26394/entropy-generation-of-unsteady-reactive-hydromagnetic-generalized-couette-fluid-flow-of-a-two-step-exothermic-chemical-reaction-through-a-channel" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26394.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">515</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=synovial%20fluid&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=synovial%20fluid&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=synovial%20fluid&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=synovial%20fluid&page=5">5</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=synovial%20fluid&page=6">6</a></li> <li class="page-item"><a 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