Drug Overdose Deaths: Facts and Figures | National Institute on Drug Abuse (NIDA)

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class="breadcrumb-list-item"> Drug Overdose Deaths: Facts and Figures </li> </ol> </nav> </div> <div data-drupal-messages-fallback class="hidden"></div> </div> </div> <div class="content"> <div class="content-inner"> <main role="main" class="main inner"> <a id="main-content" tabindex="-1"></a> <div class="above-content relative"> <div> <div id="block-nidapagetitle"> <h1 class="h1 l-inner-b"> <span>Drug Overdose Deaths: Facts and Figures </span> </h1> </div> <div class="language-switcher-language-url formats-list-block title-area font-secondary" id="block-languageswitcher-2" role="navigation"> <ul class="links formats-list no-bullets"><li hreflang="es" data-drupal-link-system-path="node/52718" class="formats-list-item language"> <span lang="es"><a href="/es/areas-de-investigacion/las-tendencias-y-estadisticas/indices-de-muertes-por-sobredosis" class="language-link" hreflang="es" data-drupal-link-system-path="node/52718">En espa帽ol</a></span> </li></ul> </div> </div> </div> <div class="main-wrapper"> <div class="layout-center-content "> <div> <div class="content-river"> <div id="block-nida-vic-adaptive-system-main"> <article data-history-node-id="52718"> <div> <div class="topic-intro-wrapper topic-intro-wrapper--research-topic full-width-wrapper l-section--accent-rt pb-1-2 mb-2-4"> <div class="topic-intro full-width-contents l-inner-sides row-no-wrap-d"> <div class="col-desktop-8 col-12"> <div class="l-card height-100 rt-highlights--wrapper"> <div><h2>Highlights</h2><div class="align-right image-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <img loading="lazy" src="/sites/default/files/styles/content_image_medium/public/images/graphiccoloredribbons.jpg?itok=l0hrm89g" width="426" height="284" alt="Visual colored bars"> </div> </div> </div> </div> <ul><li>The <a href="https://www.cdc.gov/nchs/nvss/drug-overdose-deaths.htm">National Center for Health Statistics</a> (NCHS) at the U.S. Centers for Disease Control and Prevention (CDC) reports data on fatalities involving drugs commonly associated with fatal overdose. <a href="#FAQs">NIDA analyzes NCHS data</a> to create the figures and descriptions on this page. For more information or to contact CDC, please visit the <a href="https://www.cdc.gov/nchs/nvss/drug-overdose-deaths.htm">CDC鈥檚 Drug Overdose Deaths</a> web page.</li><li>Timely data related to unintentional and undetermined intent drug overdose deaths by participating jurisdiction is also available from the CDC鈥檚 <a href="https://www.cdc.gov/overdose-prevention/data-research/facts-stats/sudors-dashboard-fatal-overdose-data.html?CDC_AAref_Val=https://www.cdc.gov/drugoverdose/fatal/dashboard/index.html">State Unintentional Drug Overdose Reporting System</a> (SUDORS) system.</li><li>Data related to nonfatal drug overdoses are reported through the <a href="https://www.cdc.gov/overdose-prevention/data-research/facts-stats/dose-dashboard-nonfatal-surveillance-data.html">CDC鈥檚 Drug Overdose Surveillance and Epidemiology</a> (DOSE) system.</li></ul></div> </div> </div> </div> </div> <div class="content-inner research-topic-inner"> <aside class="layout-sidebar-left" role="complementary"> <h2 class="research-topic-inner--title"><a href="/research-topics/trends-statistics">Trends and Statistics</a></h2> <div class="research-topic-inner--content"> <div> <div class="visually-hidden">Related Topic Pages</div> <div> <div><span>Drug Overdose Deaths: Facts and Figures</span></div> <div><a href="/research-topics/trends-statistics/monitoring-future">Monitoring the Future Survey</a></div> <div><a href="/research-topics/trends-statistics/infographics">Infographics</a></div> <div><a href="/research-topics/trends-statistics/national-drug-early-warning-system-ndews">National Drug Early Warning System (NDEWS)</a></div> </div> </div> </div> </aside> <article class="main"> <div> <div> <div class="paragraph paragraph--type--accordion paragraph--view-mode--default iq-accordion mb-2-4"> <button class="button button-primary button--small expand" aria-label="Expand All">Expand All</button> <div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig1" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths by Sex, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig1-2024.jpg" aria-label="{"alt":"This is a bar chart showing the number of U.S. overdose deaths involving select illicit or prescription drugs from 1999 through 2022. The bars are overlaid by lines representing sex or concurrent opioid involvement. There were 107,941 drug-involved overdose deaths reported in the U.S. in 2022"}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-XpLgEInZ6J0" data-cbox-img-attrs="{"alt":"This is a bar chart showing the number of U.S. overdose deaths involving select illicit or prescription drugs from 1999 through 2022. The bars are overlaid by lines representing sex or concurrent opioid involvement. There were 107,941 drug-involved overdose deaths reported in the U.S. in 2022"}"><img id="colorbox-XpLgEInZ6J0" src="/sites/default/files/styles/content_image_medium/public/images/fig1-2024.jpg?itok=Til9cUvx" width="426" height="320" alt="This is a bar chart showing the number of U.S. overdose deaths involving select illicit or prescription drugs from 1999 through 2022. The bars are overlaid by lines representing sex or concurrent opioid involvement. There were 107,941 drug-involved overdose deaths reported in the U.S. in 2022" loading="lazy"> </a> </div> </div> </div> </div> <p>Nearly 108,000 persons in the U.S. died from drug-involved overdose in 2022, including from illicit or prescription drugs (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig2" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths, Select Drugs or Drug Categories, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig2-2024.jpg" aria-label="{"alt":"Synthetic opioids other than methadone (primarily fentanyl) were the main driver of drug overdose deaths with a over 7.5-fold increase from 2015 to 2022"}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-UJ3HclW9kec" data-cbox-img-attrs="{"alt":"Synthetic opioids other than methadone (primarily fentanyl) were the main driver of drug overdose deaths with a over 7.5-fold increase from 2015 to 2022"}"><img id="colorbox-UJ3HclW9kec" src="/sites/default/files/styles/content_image_medium/public/images/fig2-2024.jpg?itok=Vm67LCN6" width="426" height="320" alt="Synthetic opioids other than methadone (primarily fentanyl) were the main driver of drug overdose deaths with a over 7.5-fold increase from 2015 to 2022" loading="lazy"> </a> </div> </div> </div> </div> <p>Overall, drug overdose deaths rose from 2019 to 2022 with 107,941 drug overdose deaths reported in 2022. Deaths involving <a href="#Fig3">synthetic opioids</a> other than methadone (primarily illicitly manufactured <a href="/research-topics/fentanyl" data-entity-type="node" data-entity-uuid="b754d032-76e9-4a4e-947f-7f5adfd15a9e" data-entity-substitution="canonical">fentanyl</a>) continued to rise with 73,838 overdose deaths reported in 2022. Those involving <a href="#Fig6">stimulants</a>, including <a href="#Fig6">cocaine</a> or psychostimulants with abuse potential (primarily <a href="#Fig7">methamphetamine</a>), also continued to increase with 27,569 and 34,022 respective deaths in 2022 (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig3" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Any Opioid by Sex, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig3-2024.jpg" aria-label="{"alt":"Drug overdose deaths involving any opioid鈥昿rescription opioids (including natural and semi-synthetic opioids and methadone), other synthetic opioids other than methadone (primarily fentanyl), and heroin鈥昪ontinued to rise through 2022 with 81,806 deaths. More than 71% of deaths occurred among males"}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-1HODQ8TmJro" data-cbox-img-attrs="{"alt":"Drug overdose deaths involving any opioid鈥昿rescription opioids (including natural and semi-synthetic opioids and methadone), other synthetic opioids other than methadone (primarily fentanyl), and heroin鈥昪ontinued to rise through 2022 with 81,806 deaths. More than 71% of deaths occurred among males"}"><img id="colorbox-1HODQ8TmJro" src="/sites/default/files/styles/content_image_medium/public/images/fig3-2024.jpg?itok=KmUttbNb" width="426" height="320" alt="Drug overdose deaths involving any opioid鈥昿rescription opioids (including natural and semi-synthetic opioids and methadone), other synthetic opioids other than methadone (primarily fentanyl), and heroin鈥昪ontinued to rise through 2022 with 81,806 deaths. More than 71% of deaths occurred among males" loading="lazy"> </a> </div> </div> </div> </div> <p>Any opioid includes prescription opioids (natural and semi-synthetic opioids and methadone), heroin, and synthetic opioids other than methadone (primarily illicitly manufactured <a href="/research-topics/fentanyl" data-entity-type="node" data-entity-uuid="b754d032-76e9-4a4e-947f-7f5adfd15a9e" data-entity-substitution="canonical">fentanyl</a>). Opioid-involved overdose deaths rose from 49,860 in 2019 to 81,806 in 2022 (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig4" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Prescription Opioids, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig4-2024.jpg" aria-label="{"alt":"From 2021 to 2022, the number of deaths involving prescription opioids declined to 14,716"}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-sM7y1D8rl7o" data-cbox-img-attrs="{"alt":"From 2021 to 2022, the number of deaths involving prescription opioids declined to 14,716"}"><img id="colorbox-sM7y1D8rl7o" src="/sites/default/files/styles/content_image_medium/public/images/fig4-2024.jpg?itok=lC0Fz1s2" width="426" height="320" alt="From 2021 to 2022, the number of deaths involving prescription opioids declined to 14,716" loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving prescription opioids rose from 3,442 in 1999 to 17,029 in 2017. From 2017 to 2019, the number of deaths declined to 14,139. This was followed by a slight increase in 2020, with 16,416 reported deaths. In 2022, the number of deaths declined to 14,716. Fentanyl involvement in fatalities that also involved prescription opioid drugs has steadily increased since 2014. This data shows that commonly prescribed opioids are no longer driving the overdose epidemic (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig5" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Heroin, by Other Opioid Involvement, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig5-2024.jpg" aria-label="{"alt":"Overdose deaths involving heroin has trended down since 2016 with 5,871 deaths reported in 2022. Nearly 80 % of overdose deaths in 2022 involving heroin also involved synthetic opioids other than methadone (primarily fentanyl)."}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-3eaizHrGauk" data-cbox-img-attrs="{"alt":"Overdose deaths involving heroin has trended down since 2016 with 5,871 deaths reported in 2022. Nearly 80 % of overdose deaths in 2022 involving heroin also involved synthetic opioids other than methadone (primarily fentanyl)."}"><img id="colorbox-3eaizHrGauk" src="/sites/default/files/styles/content_image_medium/public/images/fig5-2024.jpg?itok=yO7wfObK" width="426" height="320" alt="Overdose deaths involving heroin has trended down since 2016 with 5,871 deaths reported in 2022. Nearly 80 % of overdose deaths in 2022 involving heroin also involved synthetic opioids other than methadone (primarily fentanyl)." loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving heroin rose from 3,036 in 2010 to 15,469 in 2016. Since 2016, the number of deaths has trended down with 13,165 deaths reported in 2020, 9,173 reported deaths in 2021, and 5,871 reported deaths in 2022. While the overall number of heroin involved overdose deaths decreased, the proportion of these deaths co-involving heroin and <a href="/research-topics/fentanyl" data-entity-type="node" data-entity-uuid="b754d032-76e9-4a4e-947f-7f5adfd15a9e" data-entity-substitution="canonical">fentanyl</a> precipitously increased to nearly 80% in 2022 (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig6" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Stimulants (cocaine and psychostimulants with abuse potential), by Opioid Involvement, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig6-2024.jpg" aria-label="{"alt":"Drug overdose deaths involving stimulants, cocaine or psychostimulants with abuse potential 鈥損rimarily methamphetamine鈥攈ave significantly increased since 2015 from 12,122 to 57,497 in 2022 "}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox--i_JDHJnysQ" data-cbox-img-attrs="{"alt":"Drug overdose deaths involving stimulants, cocaine or psychostimulants with abuse potential 鈥損rimarily methamphetamine鈥攈ave significantly increased since 2015 from 12,122 to 57,497 in 2022 "}"><img id="colorbox--i_JDHJnysQ" src="/sites/default/files/styles/content_image_medium/public/images/fig6-2024.jpg?itok=gJc_pIsw" width="426" height="320" alt="Drug overdose deaths involving stimulants, cocaine or psychostimulants with abuse potential 鈥損rimarily methamphetamine鈥攈ave significantly increased since 2015 from 12,122 to 57,497 in 2022 " loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving stimulants rose from 12,122 in 2015 to 57,497 in 2022. Nearly 70% of stimulant involved overdose deaths in 2022 also involved <a href="/research-topics/fentanyl" data-entity-type="node" data-entity-uuid="b754d032-76e9-4a4e-947f-7f5adfd15a9e" data-entity-substitution="canonical">fentanyl</a> (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>). </p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig7" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Psychostimulants with Abuse Potential (Primarily Methamphetamine), by Opioid Involvement, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig7-2024.jpg" aria-label="{"alt":"Since 2015, the number of deaths involving psychostimulants (primarily methamphetamine, have risen significantly each year, with 34,022 deaths in 2022."}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-MlL6JIa7ozY" data-cbox-img-attrs="{"alt":"Since 2015, the number of deaths involving psychostimulants (primarily methamphetamine, have risen significantly each year, with 34,022 deaths in 2022."}"><img id="colorbox-MlL6JIa7ozY" src="/sites/default/files/styles/content_image_medium/public/images/fig7-2024.jpg?itok=o4NPVGfb" width="426" height="320" alt="Since 2015, the number of deaths involving psychostimulants (primarily methamphetamine, have risen significantly each year, with 34,022 deaths in 2022." loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving psychostimulants with abuse potential (primarily methamphetamine) rose from 5,716 in 2015 to 34,022 deaths in 2022. The number of deaths involving psychostimulants has increased steadily since 2014 regardless of opioid involvement (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig8" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Cocaine, by Opioid Involvement, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig8-2024.jpg" aria-label="{"alt":"The number of deaths involving cocaine have also increased steadily since 2015 with 27,569 deaths reported in 2022 "}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-vYAf7t8wpBY" data-cbox-img-attrs="{"alt":"The number of deaths involving cocaine have also increased steadily since 2015 with 27,569 deaths reported in 2022 "}"><img id="colorbox-vYAf7t8wpBY" src="/sites/default/files/styles/content_image_medium/public/images/fig8-2024.jpg?itok=dUrsH1m5" width="426" height="320" alt="The number of deaths involving cocaine have also increased steadily since 2015 with 27,569 deaths reported in 2022 " loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving <a href="/research-topics/cocaine" data-entity-type="node" data-entity-uuid="39aca104-0936-4e64-9e8f-c9e537de28d4" data-entity-substitution="canonical">cocaine</a> rose steadily from 6,784 in 2015 to 15,883 in 2019; and again from 2019 to 2022, with a 73.5% increase to 27,569 deaths. The number of deaths in combination with fentanyl has increased significantly since 2015 and is the main driver of cocaine-involved overdose deaths (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig9" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Benzodiazepines, by Opioid Involvement, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig9-2024.jpg" aria-label="{"alt":"This figure shows the number of overdose deaths involving benzodiazepines. Benzodiazepines were involved in 10,964 deaths in 2022鈥攁 decrease from 2021. The proportion of fatalities involving synthetic opioids other than methadone (fentanyl) has increased significantly since 2015"}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-j1HuqfDpYeE" data-cbox-img-attrs="{"alt":"This figure shows the number of overdose deaths involving benzodiazepines. Benzodiazepines were involved in 10,964 deaths in 2022鈥攁 decrease from 2021. The proportion of fatalities involving synthetic opioids other than methadone (fentanyl) has increased significantly since 2015"}"><img id="colorbox-j1HuqfDpYeE" src="/sites/default/files/styles/content_image_medium/public/images/fig9-2024.jpg?itok=NtCmyTof" width="426" height="320" alt="This figure shows the number of overdose deaths involving benzodiazepines. Benzodiazepines were involved in 10,964 deaths in 2022鈥攁 decrease from 2021. The proportion of fatalities involving synthetic opioids other than methadone (fentanyl) has increased significantly since 2015" loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving benzodiazepines steadily increased from 1,135 in 1999 to 11,537 in 2017 followed by a decline to 9,711 deaths in 2019. Between 2019 and 2021, deaths rose again to 12,499. In 2022, the number of drug overdose deaths involving benzodiazepines declined to 10,964 (Source: <a href="http://wonder.cdc.gov/">CDC WONDER</a>).</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Fig10" class="iq-accordion--heading" aria-expanded="false"><h2>U.S. Overdose Deaths Involving Antidepressants, by Opioid Involvement, 1999-2022</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><div class="align-right colorbox-medium"> <div class="media-image"> <div> <div class="visually-hidden">Image</div> <div> <a href="https://nida.nih.gov/sites/default/files/images/fig10-2024.jpg" aria-label="{"alt":"This chart shows the number of overdose deaths involving antidepressants. The proportion of fatalities involving synthetic opioids other than methadone (fentanyl) has increased significantly since 2015. Of the 8,791 deaths in 2015, 20% also involved fentanyl. Antidepressant involved deaths have"}" role="button" title data-colorbox-gallery="gallery-all-D0u_XTm41q4" class="colorbox" aria-controls="colorbox-8ckGiz2RmdY" data-cbox-img-attrs="{"alt":"This chart shows the number of overdose deaths involving antidepressants. The proportion of fatalities involving synthetic opioids other than methadone (fentanyl) has increased significantly since 2015. Of the 8,791 deaths in 2015, 20% also involved fentanyl. Antidepressant involved deaths have"}"><img id="colorbox-8ckGiz2RmdY" src="/sites/default/files/styles/content_image_medium/public/images/fig10-2024.jpg?itok=5Dn67heI" width="426" height="320" alt="This chart shows the number of overdose deaths involving antidepressants. The proportion of fatalities involving synthetic opioids other than methadone (fentanyl) has increased significantly since 2015. Of the 8,791 deaths in 2015, 20% also involved fentanyl. Antidepressant involved deaths have" loading="lazy"> </a> </div> </div> </div> </div> <p>Drug overdose deaths involving antidepressants have steadily risen from 1,749 in 1999 to 5,863 in 2022 (Source: <a href=" http://wonder.cdc.gov/">CDC WONDER)</a>.</p></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="Download" class="iq-accordion--heading" aria-expanded="false"><h2>Download Links</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><ul><li>Download graphs in PowerPoint - <a class="ppt" href="/sites/default/files/drug-involved-overdose-deaths-1999-2022.pptx">National Drug Involved Overdose Deaths 1999-2022.pptx</a></li><li>Download the data used to create these figures - <a class="xls" href="/sites/default/files/overdose_data_1999-2022_5.2.2024.xlsx">Overdose_data_1999-2022 5.7.24.xlsx</a></li></ul></div> </div> </div> <div> <div class="paragraph paragraph--type--accordion-row iq-accordion--row paragraph--view-mode--default clear-both mt-0-0"> <button id="FAQs" class="iq-accordion--heading" aria-expanded="false"><h2>Frequently Asked Questions</h2><span class="iq-accordion--toggle closed h3"></span></button> <div class="iq-accordion--content" aria-hidden="true"><h3>Does NIDA collect and release the data on this webpage?</h3><p>No. The <a href="https://www.cdc.gov/nchs/nvss/drug-overdose-deaths.htm">National Center for Health Statistics</a> (NCHS) at the Centers for Disease Control and Prevention collects and reports these data, which are available to the public and can be accessed from an ad-hoc query system called <a href="http://wonder.cdc.gov/">CDC WONDER鈥擶ide-ranging Online Data for Epidemiologic Research</a>. NIDA does not fund or assist in the collection of these data but does analyze NCHS data to create the figures and descriptions on this page. </p><h3>Why are the statistics displayed not more recent? Where can I find more recent estimates of overdose death rates?</h3><p>This webpage is regularly updated to display the most recent final drug overdose death data published annually by NCHS. NCHS systems receive and analyze data from death certificates, including cause-of-death information reported by state and local medical examiners and coroners. Because drug overdose deaths often require lengthy investigations, data are updated as new information is received.</p><p>For more recent provisional data, please see <a href="https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm">Provisional Drug Overdose Death Counts</a> from NCHS. Timely data related to unintentional and undetermined intent drug overdose deaths by participating jurisdiction is also available from the CDC鈥檚 <a href="https://www.cdc.gov/overdose-prevention/data-research/facts-stats/sudors-dashboard-fatal-overdose-data.html?CDC_AAref_Val=https://www.cdc.gov/drugoverdose/fatal/dashboard/index.html">State Unintentional Drug Overdose Reporting System</a> (SUDORS). Similar data related to nonfatal drug overdoses are reported through <a href="https://www.cdc.gov/overdose-prevention/data-research/facts-stats/dose-dashboard-nonfatal-surveillance-data.html">CDC鈥檚 Drug Overdose Surveillance and Epidemiology</a> (DOSE) system.</p><h3>Where can I find more information about the data displayed on this webpage?</h3><p>For more information or to contact CDC, please visit the <a href="https://www.cdc.gov/nchs/nvss/drug-overdose-deaths.htm">CDC鈥檚 Drug Overdose Deaths webpage</a>.</p></div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--summary-cards-row-of-2 paragraph--view-mode--default l-section"> <div class="l-inner-b card-grid"> </div> </div> </div> <div class="mb-3-6"><div class="views-element-container" id="block-views-block-latest-from-nida-block-16"> <h2>Latest from NIDA</h2> <div><div class="media-list js-view-dom-id-c2b320ba51af979d9b3fda477b390193f2139779aaaed3d64f84bb2cc0d36c39"> <div class="media-list-item 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on the CDC web site.</li><li>Explore the Overdose Prevention and Response Toolkit from the <a href="https://store.samhsa.gov/product/overdose-prevention-response-toolkit/pep23-03-00-001">Substance Abuse and Mental Health Services Administration</a>.</li></ul></div> </div> </div> </div> </article> <aside class="layout-sidebar-right article-aside" role="complementary"> <div class="citation-block" id="block-citation"> <div class="citation"> <button class="citation-header button button-primary-alt button--small" aria-expanded="false" tabindex="0"> <span class="pointer-background"><i class="fas fa-quote-left"></i> Cite this article</span> </button> <div class="citation-content"> <div class="tabs-wrapper"> <button class="tab-button active button button-secondary-alt button--small" data-click="selectme1">APA Style</button> <button class="tab-button button button-secondary-alt button--small" data-click="selectme2">MLA Style</button> <button class="tab-button button button-secondary-alt 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Poison control can be reached at <a href="tel:1-800-222-1222" style="color:#A42629; border-color:#A42629;">1-800-222-1222</a> or <a href="https://www.poison.org" style="color:#A42629; border-color:#A42629;">www.poison.org</a>. </li> <li><strong>Are you or someone you know experiencing a substance use and/or mental health crisis or any other kind of emotional distress?</strong> Please <strong>call or text 988</strong> or chat <a href="https://www.988lifeline.org" style="color:#A42629; border-color:#A42629;">www.988lifeline.org</a> to reach the 988 Suicide & Crisis Lifeline. 988 connects you with a trained crisis counselor who can help.</li> </ul> <h3>FIND TREATMENT:</h3> <ul style="margin-left:1.3rem;"> <li>For referrals to substance use and mental health treatment programs, call the Substance Abuse and Mental Health Administration (SAMHSA) National Helpline at <a href="tel:1-800-6620-4357" style="color:#A42629; border-color:#A42629;">1-800-662-HELP (4357)</a> or visit <a href="https:///www.findtreatment.gov" style="color:#A42629; border-color:#A42629;">www.FindTreatment.gov</a> to find a qualified healthcare provider in your area.</li> <li>For other personal medical advice, please speak to a qualified health professional. Find more health resources on <a href="https://www.usa.gov/health" style="color:#A42629; border-color:#A42629;">USA.gov</a>.</li> </ul> <h3>DISCLAIMER:</h3> <p><em>The emergency and referral resources listed above are available to individuals located in the United States and are not operated by the National Institute on Drug Abuse (NIDA). NIDA is a biomedical research organization and does not provide personalized medical advice, treatment, counseling, or legal consultation. 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Drug Overdose Deaths: Facts and Figures | National Institute on Drug Abuse (NIDA)