CINXE.COM

Recombinant Human/Mouse FGF-8b Protein (423-F8): Novus Biologicals

<!DOCTYPE html> <html> <head> <meta charset="UTF-8"><script type="text/javascript">(window.NREUM||(NREUM={})).init={privacy:{cookies_enabled:true},ajax:{deny_list:[]},session_replay:{sampling_rate:10.0,mask_text_selector:"",block_selector:"",mask_input_options:{date:true,text_area:true,week:true,select:true,color:true,range:true,textarea:true,url:true,number:true,search:true,month:true,datetime_local:true,tel:true,text:true,time:true,email:true},enabled:true,error_sampling_rate:100.0}};(window.NREUM||(NREUM={})).loader_config={xpid:"UA8FUVBADwsIV1VaAgQD",licenseKey:"76fb58fb05",applicationID:"788348554"};;/*! For license information please see nr-loader-full-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>d});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function d(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>p,xN:()=>g});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const d="[data-nr-mask]",u=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(d):""===t||null===t?e.mask_selector=d:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function g(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,u());const r=(0,s.nY)(e);r&&(r.init=l[e])}function p(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},d={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},u={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!u[e])throw new Error("Runtime for ".concat(e," was never set"));return u[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");u[e]={...(0,n.a)(t,d),...c},Object.hasOwnProperty.call(u[e],"harvestCount")||Object.defineProperty(u[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=u[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.274.0",i="PROD",o="CDN",a="^2.0.0-alpha.17"},6154:(e,t,r)=>{"use strict";r.d(t,{OF:()=>d,RI:()=>i,WN:()=>f,bv:()=>o,gm:()=>a,lR:()=>l,m:()=>c,mw:()=>s,sb:()=>u});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s=Boolean("hidden"===a?.document?.visibilityState),c=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),u=d&&"undefined"==typeof SharedWorker,l=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),f=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>d});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};u(e),s[e].get(t)||s[e].set(t,r)}function d(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function u(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(u(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)g(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function g(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>d});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),d=function e(t,r){var n={},s={},u={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:g,addEventListener:g,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(d.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=p(e),u=c.length,l=0;l<u;l++)c[l].apply(a,r);var g=v()[s[e]];g&&g.push([f,e,r,a]);return a},get:m,listeners:p,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function g(e,t){n[e]=p(e).concat(t)}function p(e){return n[e]||[]}function m(t){return u[t]=u[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),u=(0,n.Zm)();u.ee||(u.ee=d)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>d});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function d(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>d,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},d={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>u,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>d,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function d(e){let t=a();return t.initializedAgents?.[e]}function u(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,d="addEventListener",u="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[d,u],"-",g)}function g(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(d+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(u+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,d);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],d=e[c];u(d)||(e[c]=r(d,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return u(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){d([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,u,l;try{a=this,o=[...arguments],u="function"==typeof n?n(o,a):n||{}}catch(t){d([t,"",[o,a,s],u],e)}i(r+"start",[o,a,s],u,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],u,c),e}finally{i(r+"end",[o,a,l],u,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){d([t,r,n,i],e)}s=a}}}function d(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function u(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>d});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function d(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>u,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>d,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},d={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},u=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>d,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function d(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>d,Rz:()=>u,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,d="fn"+s,u="pushState",l=1e3},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>P});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),d=r(5289),u=r(6154),l=r(944),f=r(3969),h=r(384),g=r(6344);const p=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",g.G4.RECORD,g.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),R=r(3785),x=r(2646),w=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,w.YM)(i),a=new x.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();p.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),_=r(5603),O=r(5284);const N=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function P(e,t={},p,x){let{init:w,info:P,loader_config:j,runtime:C={},exposed:k=!0}=t;C.loaderType=p;const H=(0,h.pV)();P||(w=H.init,P=H.info,j=H.loader_config),(0,S.xN)(e.agentIdentifier,w||{}),(0,_.a)(e.agentIdentifier,j||{}),P.jsAttributes??={},u.bv&&(P.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,P);const D=(0,S.D0)(e.agentIdentifier),L=[P.beacon,P.errorBeacon];I||(D.proxy.assets&&(N(D.proxy.assets),L.push(D.proxy.assets)),D.proxy.beacon&&L.push(D.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===D.soft_navigations.enabled&&D.feature_flags.includes("soft_nav")),C.denyList=[...D.ajax.deny_list||[],...D.ajax.block_internal?L:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const p={};var x=s.ee.get(e),w=x.get("tracer");E[e]=b.g.OFF,x.on(g.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function _(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}p.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,x),(0,R.R)(x,e,t,r)},p.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,x),T(x,e,t,{customAttributes:r,level:i})},m.forEach((e=>{p[e]=I(A,e,!0,"api")})),p.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),p.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},p.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return _(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},p.setUserId=function(e){if("string"==typeof e||null===e)return _("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},p.setApplicationVersion=function(e){if("string"==typeof e||null===e)return _("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},p.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,x),x.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},p[g.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,x),(0,a.p)(g.G4.RECORD,[],void 0,n.K7.sessionReplay,x)},p[g.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,x),(0,a.p)(g.G4.PAUSE,[],void 0,n.K7.sessionReplay,x)},p.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const N=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,x),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,x),function(){if(w.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw w.emit("fn-err",[arguments,this,t],r),t}finally{w.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,x),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,x),r?void 0:this}}function P(){r.e(891).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),x.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{N[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),p.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),p.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,x),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,x)},u.RI?(0,d.GG)((()=>P()),!0):P(),p}(e.agentIdentifier,x,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({95:"nr-full-compressor",222:"nr-full-recorder",891:"nr-full"}[e]+"-1.274.0.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var d=document.getElementsByTagName("script"),u=0;u<d.length;u++){var l=d[u];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={891:"sha512-Sx2xJQrHp2m/Ngn/ZcfBCUwNr2Xy/C5urYtWpfm3bWpil4spXOQGTtNwIfF5HvPGioGASn9QTyE4Z+zC7r7wcg==",222:"sha512-hMte3OWgwwYeisSiD7WCIx/6tT16zLaPjag9uF4tIZp7ybOvrJKbeyzhe4fz1tDbkdcdOMm8dvgPPLBatSAGeA==",95:"sha512-MPaT9dkHv16XzwEUVZPyqpN1do/Er1XFAZoIAPYWylmv+iGIThqN+GwQq27pUyAX7sNXVJQVZezH96p53Ks3Pg=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(g);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},g=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={959:0,85:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,d=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);d<a.length;d++)o=a[d],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function d(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var u=i(425);var l=i(1687),f=i(4234),h=i(5289),g=i(6154),p=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(891).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(891).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(891).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};g.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,p.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class R extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var x=i(384);var w=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class _ extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),g.RI&&((0,T.u)((()=>(0,w.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,w.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class N extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),P=i(3304);class j{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,P.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return D(e)?e:new j(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(D(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function H(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new j(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return D(e.error)?e.error:C(e)}function D(e){return e instanceof Error&&!!e.stack}class L extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,w.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),g.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,w.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),g.gm.addEventListener("error",(e=>{this.abortHandler&&(0,w.p)("err",[H(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var K=i(8990);let M=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===g.gm?0:(0,K.I)(e,U,(function(){return M++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,P.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=g.gm.XMLHttpRequest,a=g.gm.MutationObserver,s=g.gm.Promise,c=g.gm.setInterval,d="readystatechange",u=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=g.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(d,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,u,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(p?p.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var p=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===d||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",Q=["arrayBuffer","blob","json","text","formData"],J=g.gm.Request,ee=g.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(J&&ee&&g.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,Q.forEach((e=>{r(J[te],e,X),r(ee[te],e,X)})),r(g.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),d={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(d.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),d.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(d.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),d}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof g.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,P.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),de=["load","error","abort","timeout"],ue=de.length,le=(0,x.dV)().o.REQ,fe=(0,x.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,w.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};g.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};ge(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=x,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),g.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},ge(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<ue;s++)r.addEventListener(de[s],this.listener,(0,A.jT)(!1))}function d(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function u(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function p(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&g.RI&&(t=""+g.gm.location.href):e[0]&&e[0].url?t=e[0].url:g.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:g.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),ge(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function R(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function x(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<ue;t++)e.removeEventListener(de[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,w.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",d),t.on("xhr-load-added",u),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",p),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",R)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function ge(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const pe={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!g.RI||pe[t.debugId]++||(pe[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:Re,d3:xe,Kp:we,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class _e extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,w.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+xe,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+we,(function(e){(0,w.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,w.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:Re,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class Ne extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,p.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,w.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,p.Aw)(this.agentIdentifier)}#d=!1;async#c(e){if(!this.#d){this.#d=!0;try{const{Recorder:t}=await Promise.all([i.e(891),i.e(222)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3333);class Pe extends b{static featureName=Ie.TZ;constructor(e,t=!0){super(e,Ie.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];g.RI&&e.init.user_actions.enabled&&(Ie.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,w.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),Ie.qN.forEach((e=>(0,A.sp)(e,(e=>(0,w.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var je=i(993),Ce=i(3785);class ke extends b{static featureName=je.TZ;constructor(e,t=!0){super(e,je.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,Ce.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),g.gm?(this.features={},(0,x.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(R),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,u.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=d(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,x.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[R,_,_e,Ne,he,N,L,Pe,ke],loaderType:"pro"})})()})();</script> <meta charset="UTF-8" /> <meta name="keywords" content="FGF-8, FGF-8 (423-F8), Novus Biologicals, 423-F8" /> <link rel="canonical" href="https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8" /> <title>Recombinant Human/Mouse FGF-8b Protein (423-F8): Novus Biologicals</title> <meta name="description" content="Recombinant Human/Mouse FGF-8b Protein. Backed by our 100% Guarantee." /> <meta property="og:description" content="Recombinant Human/Mouse FGF-8b Protein. Backed by our 100% Guarantee." /> <meta property="og:image" content="//images.novusbio.com/thumbnails2/FGF8_423F8_1438.jpg" /> <meta refresh_date="11/27/2024 2:28:32 AM" /> <meta name="baidu-site-verification" content="xQr2vSIwwB" /> <script id="json-ld" type="application/ld+json">[{"@context":"http://schema.org","@type":"Product","description":"Recombinant Human/Mouse FGF-8b Protein. Backed by our 100% Guarantee.","aggregateRating":{"@type":"AggregateRating","ratingValue":5,"reviewCount":1},"offers":[],"url":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","name":"Recombinant Human/Mouse FGF-8b Protein","productID":"423-F8","mpn":"423-F8","sku":"423-F8","brand":{"@type":"Brand","name":"Novus Biologicals"},"itemcondition":"new","image":[{"@type":"ImageObject","url":"//images.novusbio.com/fullsize2/FGF8_423F8_1438.jpg","caption":"Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R\u20113T3 mouse fibroblast cell line. The ED50 for this effect is 6.5-40 ng/mL in the presence of 1 \u03bcg/mL heparin.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize2/FGF-8_423-F8_332.jpg","caption":"1 \u03bcg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/423-f8_recombinant-human-mouse-fgf-8b-protein-cell-culture-1052024145159..jpg","caption":"Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively) to select and enrich for neural stem cell populations, and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Cells were stained with a Mouse Anti-Human/Mouse Tyrosine Hydroxylase Monoclonal Antibody (MAB7566) followed by a NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green), and a Mouse Neuron-specific beta III Tubulin Tuj1 Monoclonal Antibody (MAB1195) followed by a NorthernLights 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red) and counterstained with DAPI (5748; blue). ","width":400,"height":400},{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/423-f8_recombinant-human-mouse-fgf-8b-protein-cell-culture-1052024145958..jpg","caption":"Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively), and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Tyrosine Hydroxylase was detected using a Mouse Anti-Human Tyrosine Hydroxylase Monoclonal Antibody (MAB7566). The cells were stained with the NorthernLights&#8482; 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red). Neuron-specific beta-III Tubulin was detected using a Mouse Anti-Neuron-specific beta-III Tubulin (Clone Tuj-1) Monoclonal Antibody (MAB1195) followed by the NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green). Cells were counterstained with DAPI (5748; blue). ","width":400,"height":400}],"review":[{"@type":"Review","author":"Anonymous","datePublished":"Sep 11 2019 3:30PM","name":"Recombinant Human/Mouse FGF-8b Protein","reviewRating":{"@type":"Rating","bestRating":"5","ratingValue":5,"worstRating":"1"}}],"isRelatedTo":[{"@type":"Product","name":"FGF-8 Antibodies","url":"https://www.novusbio.com/primary-antibodies/fgf-8"},{"@type":"Product","name":"FGF-8 ELISA Kits","url":"https://www.novusbio.com/elisa-kits/fgf-8"},{"@type":"Product","name":"FGF-8 Lysate","url":"https://www.novusbio.com/lysates/fgf-8"},{"@type":"Product","name":"FGF-8 Protein","url":"https://www.novusbio.com/proteins/fgf-8"},{"@type":"Product","name":"FGF-8 Proteins and Enzymes","url":"https://www.novusbio.com/proteins-and-enzymes/fgf-8"}]},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Ligand bias underlies differential signaling of multiple FGFs via FGFR1 ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2024-04-03","publisher":{"@type":"Organization","name":"eLife"},"author":{"@type":"person","name":"Karl, K;Del Piccolo, N;Light, T;Roy, T;Deduja, P;Ursachi, VC;Fafilek, B;Krejci, P;Hristova, K;"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Simplified drug efficacy evaluation system for vasopressin neurodegenerative disease using mouse disease-specific induced pluripotent stem cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2024-01-10","publisher":{"@type":"Organization","name":"Peptides"},"author":{"@type":"person","name":"Miwata, T;Suga, H;Mitsumoto, K;Zhang, J;Hamada, Y;Sakakibara, M;Soen, M;Ozaki, H;Asano, T;Miyata, T;Kawaguchi, Y;Yasuda, Y;Kobayashi, T;Sugiyama, M;Onoue, T;Hagiwara, D;Iwama, S;Oyadomari, S;Arima, H;"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2024-04-01","publisher":{"@type":"Organization","name":"Neural regeneration research"},"author":{"@type":"person","name":"Chen, Y;Kuang, J;Niu, Y;Zhu, H;Chen, X;So, KF;Xu, A;Shi, L;"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Unconventional secretion of alpha-synuclein mediated by palmitoylated DNAJC5 oligomers ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2023-01-10","publisher":{"@type":"Organization","name":"Elife, 2023-01-10;12(0):."},"author":{"@type":"person","name":"S Wu, NC Hernandez, DW Sirkis, I Thomas-Wri, R Wade-Marti, R Schekman"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" A reference human induced pluripotent stem cell line for large-scale collaborative studies ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2022-12-01","publisher":{"@type":"Organization","name":"Cell Stem Cell, 2022-12-01;29(12):1685-1702.e22."},"author":{"@type":"person","name":"CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendra, L Peng, H Oguro, J Kanaujiya, J Zou, D Sebesta, G Pratt, E Cross, J Blockwick, P Buxton, L Kinner-Bib, C Medura, C Tompkins, S Hughes, M Santiana, F Faghri, MA Nalls, D Vitale, S Ballard, YA Qi, DM Ramos, KM Anderson, J Stadler, P Narayan, J Papademetr, L Reilly, MP Nelson, S Aggarwal, LU Rosen, P Kirwan, V Pisupati, SL Coon, SW Scholz, T Priebe, M \u00d6ttl, J Dong, M Meijer, LJM Janssen, VS Lourenco, R van der Ka, D Crusius, D Paquet, AC Raulin, G Bu, A Held, BJ Wainger, RMC Gabriele, JM Casey, S Wray, D Abu-Bonsra, CL Parish, MS Beccari, DW Cleveland, E Li, IVL Rose, M Kampmann, C Calatayud, P Verstreken, L Heinrich, MY Chen, B Sch\u00fcle, D Dou, ELF Holzbaur, MC Zanellati, R Basundra, M Deshmukh, S Cohen, R Khanna, M Raman, ZS Nevin, M Matia, J Van Lent, V Timmerman, BR Conklin, K Johnson Ch, K Zhang, S Funes, DA Bosco, L Erlebach, M Welzer, D Kronenberg, G Lyu, E Arenas, E Coccia, L Sarrafha, T Ahfeldt, JC Marioni, WC Skarnes, MR Cookson, ME Ward, FT Merkle"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2022-10-25","publisher":{"@type":"Organization","name":"Cell Reports, 2022-10-25;41(4):111545."},"author":{"@type":"person","name":"JS Park, J Choi, L Cao, J Mohanty, Y Suzuki, A Park, D Baker, J Schlessing, S Lee"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2022-10-17","publisher":{"@type":"Organization","name":"Scientific Reports, 2022-10-17;12(1):17381."},"author":{"@type":"person","name":"H Ozaki, H Suga, M Sakakibara, M Soen, N Miyake, T Miwata, S Taga, T Nagai, M Kano, K Mitsumoto, T Miyata, T Kobayashi, M Sugiyama, T Onoue, H Takagi, D Hagiwara, S Iwama, R Banno, G Iguchi, Y Takahashi, K Muguruma, H Inoue, H Arima"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2022-09-27","publisher":{"@type":"Organization","name":"Stem Cells International, 2022-09-27;2022(0):1092184."},"author":{"@type":"person","name":"DS Lee, YJ Song, HR Gug, JH Lee, HS Bae, JC Park"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2022-01-07","publisher":{"@type":"Organization","name":"Cancers, 2022-01-07;14(2):."},"author":{"@type":"person","name":"L Yu, M Toriseva, S Afshan, M Cangiano, V Fey, A Erickson, H Seikkula, K Alanen, P Taimen, O Ettala, M Nurmi, PJ Bostr\u00f6m, M Kallajoki, J Tuomela, T Mirtti, IJ Beumer, M Nees, P H\u00e4rk\u00f6nen"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Induction of gammadeltaT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2021-10-23","publisher":{"@type":"Organization","name":"Journal of Cellular and Molecular Medicine, 2021-10-23;0(0):."},"author":{"@type":"person","name":"N Hosaka, S Kanda, T Shimono, T Nishiyama"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" 3D Bioprinting Mesenchymal Stem Cell-Derived Neural Tissues Using a Fibrin-Based Bioink ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2021-08-21","publisher":{"@type":"Organization","name":"Biomolecules, 2021-08-21;11(8):."},"author":{"@type":"person","name":"M Restan Per, R Sharma, NZ Masri, SM Willerth"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2021-02-13","publisher":{"@type":"Organization","name":"Journal of Cellular and Molecular Medicine, 2021-02-13;0(0):."},"author":{"@type":"person","name":"C Zhou, D Chen, J Ren, D Huang, R Li, H Luo, C Guan, Y Cao, W Wang"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2021-02-04","publisher":{"@type":"Organization","name":"Cell Stem Cell, 2021-02-04;28(2):343-355.e5."},"author":{"@type":"person","name":"TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel, ND Socci, SJ Choi, S Zabierowsk, BN Dubose, EJ Hill, EV Mosharov, S Irion, MJ Tomishima, V Tabar, L Studer"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Control of mesenchymal cell fate via application of FGF-8b in vitro ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2021-01-07","publisher":{"@type":"Organization","name":"Stem Cell Research, 2021-01-07;51(0):102155."},"author":{"@type":"person","name":"T Otsuka, PY Mengsteab, CT Laurencin"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2020-08-25","publisher":{"@type":"Organization","name":"EMBO Mol Med, 2020-08-25;0(0):e12146."},"author":{"@type":"person","name":"KX Liang, CK Kristianse, S Mostafavi, GH Vatne, GA Zantingh, A Kianian, C Tzoulis, LE H\u00f8yland, M Ziegler, RM Perez, J Furriol, Z Zhang, N Balafkan, Y Hong, R Siller, GJ Sullivan, LA Bindoff"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson&#039;s disease ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2020-08-08","publisher":{"@type":"Organization","name":"Stem Cell Res Ther, 2020-08-08;11(1):347."},"author":{"@type":"person","name":"JL Goggi, L Qiu, MC Liao, S Khanapur, L Jiang, R Boominatha, SV Hartimath, P Cheng, FF Yong, V Soh, X Deng, YM Lin, A Haslop, PW Tan, X Zeng, JWL Lee, Z Zhang, P Sadasivam, EK Tan, SK Luthra, WD Shingleton, SKW Oh, L Zeng, EG Robins"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Combined Dendritic and Axonal Deterioration Are Responsible for Motoneuronopathy in Patient-Derived Neuronal Cell Models of Chorea-Acanthocytosis ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2020-03-05","publisher":{"@type":"Organization","name":"Int J Mol Sci, 2020-03-05;21(5):."},"author":{"@type":"person","name":"H Gla beta , P Neumann, A Pal, P Reinhardt, A Storch, J Sternecker, A Hermann"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2019-11-27","publisher":{"@type":"Organization","name":"Cell Death Dis, 2019-11-27;10(12):898."},"author":{"@type":"person","name":"S Mahajani, A Raina, C Fokken, S K\u00fcgler, M B\u00e4hr"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2019-06-11","publisher":{"@type":"Organization","name":"Sci Rep, 2019-06-11;9(1):8470."},"author":{"@type":"person","name":"S Westphal, T Gantert, C Kless, K H\u00fcttinger, M Klingenspo, T Fromme"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Modeling Motor Neuron Resilience in ALS Using Stem Cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2019-05-09","publisher":{"@type":"Organization","name":"Stem Cell Reports, 2019-05-09;0(0):."},"author":{"@type":"person","name":"I Allodi, J Nijssen, JA Benitez, C Schweingru, A Fuchs, G Bonvicini, M Cao, O Kiehn, E Hedlund"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson&#039;s Disease Patients ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2019-02-22","publisher":{"@type":"Organization","name":"Front Cell Neurosci, 2019-02-22;13(0):58."},"author":{"@type":"person","name":"M Elkouris, G Kouroupi, A Vourvoukel, N Papagianna, V Kaltezioti, R Matsas, L Stefanis, M Xilouri, PK Politis"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2018-06-01","publisher":{"@type":"Organization","name":"Front Pharmacol, 2018-06-01;9(0):572."},"author":{"@type":"person","name":"G Collo, L Cavalleri, M Zoli, U Maskos, E Ratti, E Merlo Pich"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2018-06-13","publisher":{"@type":"Organization","name":"Cell Transplant, 2018-06-13;0(0):9636897187803."},"author":{"@type":"person","name":"J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Efficient induction of functional ameloblasts from human keratinocyte stem cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2018-05-02","publisher":{"@type":"Organization","name":"Stem Cell Res Ther, 2018-05-02;9(1):126."},"author":{"@type":"person","name":"X Hu, JW Lee, X Zheng, J Zhang, X Lin, Y Song, B Wang, X Hu, HH Chang, Y Chen, CP Lin, Y Zhang"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2018-02-04","publisher":{"@type":"Organization","name":"Neural Plast., 2018-02-04;2018(0):4196961."},"author":{"@type":"person","name":"G Collo, L Cavalleri, F Bono, C Mora, S Fedele, RW Invernizzi, M Gennarelli, G Piovani, T Kunath, MJ Millan, E Merlo Pich, P Spano"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Effects of Passage Number and Differentiation Protocol on the Generation of Dopaminergic Neurons from Rat Bone Marrow-Derived Mesenchymal Stem Cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2018-03-02","publisher":{"@type":"Organization","name":"Int J Mol Sci, 2018-03-02;19(3):."},"author":{"@type":"person","name":"G Shall, M Menosky, S Decker, P Nethala, R Welchko, X Leveque, M Lu, M Sandstrom, U Hochgeschw, J Rossignol, G Dunbar"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Chromosomal instability during neurogenesis in Huntington&#039;s disease ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2018-01-29","publisher":{"@type":"Organization","name":"Development, 2018-01-29;145(2):."},"author":{"@type":"person","name":"A Ruzo, GF Croft, JJ Metzger, S Galgoczi, LJ Gerber, C Pellegrini, H Wang, M Fenner, S Tse, A Marks, C Nchako, AH Brivanlou"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2017-10-22","publisher":{"@type":"Organization","name":"Stem Cells Int, 2017-10-22;2017(0):9605432."},"author":{"@type":"person","name":"T Johansen, C Krabbe, SI Schmidt, AM Serrano, M Meyer"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2017-03-07","publisher":{"@type":"Organization","name":"Proc. Natl. Acad. Sci. U.S.A, 2017-03-07;0(0):."},"author":{"@type":"person","name":"AR Rodrigues, N Yakushiji-, Y Atsuta, G Andrey, P Schorderet, D Duboule, CJ Tabin"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Neurotoxic reactive astrocytes are induced by activated microglia ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2017-01-18","publisher":{"@type":"Organization","name":"Nature, 2017-01-18;541(7638):481-487."},"author":{"@type":"person","name":"SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE M\u0081nch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2016-11-23","publisher":{"@type":"Organization","name":"J. Neurosci., 2016-11-23;36(47):12027-12043."},"author":{"@type":"person","name":"Florian Wegner"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: Effects on Embryo Survival ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2016-07-08","publisher":{"@type":"Organization","name":"J Biol Chem, 2016-07-08;0(0):."},"author":{"@type":"person","name":""}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson&#039;s Disease: Preliminary Clinical and Cell Line Data ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2016-06-16","publisher":{"@type":"Organization","name":"PLoS ONE, 2016-06-16;11(6):e0157602."},"author":{"@type":"person","name":"Daniel A Monti"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2016-06-01","publisher":{"@type":"Organization","name":"Sci Rep, 2016-06-01;6(0):26448."},"author":{"@type":"person","name":"Eva Hedlund"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2015-06-15","publisher":{"@type":"Organization","name":"PLoS ONE, 2015-06-15;10(6):e0130147."},"author":{"@type":"person","name":"Chan W, Howe K, Clegg J, Guimond S, Price D, Turnbull J, Pratt T"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Susceptibility of human embryonic stem cell-derived neural cells to Japanese encephalitis virus infection. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2014-12-17","publisher":{"@type":"Organization","name":"PLoS ONE, 2014-12-17;9(12):e114990."},"author":{"@type":"person","name":"Shen , Shih-Che, Shen , Ching-I, Lin , Ho, Chen , Chun-Jun, Chang , Chia-Yu, Chen , Sheng-Me, Lee , Hsiu-Chi, Lai , Ping-Sha, Su , Hong-Lin"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Collective cell migration of the nephric duct requires FGF signaling. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2014-12-30","publisher":{"@type":"Organization","name":"Dev Dyn, 2014-12-30;244(2):157-67."},"author":{"@type":"person","name":"Attia L, Schneider J, Yelin R, Schultheiss T"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Etv1 and Ewsr1 cooperatively regulate limb mesenchymal Fgf10 expression in response to apical ectodermal ridge-derived fibroblast growth factor signal. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2014-08-07","publisher":{"@type":"Organization","name":"Dev Biol, 2014-08-07;394(1):181-90."},"author":{"@type":"person","name":"Yamamoto-Shiraishi Y, Higuchi H, Yamamoto S, Hirano M, Kuroiwa A"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Manipulating gene expression and signaling activity in cultured mouse limb bud cells. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2014-04-17","publisher":{"@type":"Organization","name":"Dev Dyn, 2014-04-17;243(7):928-36."},"author":{"@type":"person","name":"Lewandowski J, Pursell T, Rabinowitz A, Vokes S"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Transcription factor-induced lineage programming of noradrenaline and motor neurons from embryonic stem cells. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2014-03-01","publisher":{"@type":"Organization","name":"Stem Cells, 2014-03-01;32(3):609-22."},"author":{"@type":"person","name":"Mong J, Panman L, Alekseenko Z, Kee N, Stanton L, Ericson J, Perlmann T"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2013-12-20","publisher":{"@type":"Organization","name":"PLoS ONE, 2013-12-20;8(12):e84504."},"author":{"@type":"person","name":"Ni , Na, Hu , Yaohua, Ren , Huixia, Luo , Chuanmin, Li , Peng, Wan , Jian-Bo, Su , Huanxing"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2013-12-17","publisher":{"@type":"Organization","name":"PLoS ONE, 2013-12-17;8(12):e85087."},"author":{"@type":"person","name":"McCarroll , Matthew, Nechiporuk , Alex V"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" MicroRNA-based promotion of human neuronal differentiation and subtype specification. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2013-03-18","publisher":{"@type":"Organization","name":"PLoS ONE, 2013-03-18;8(3):e59011."},"author":{"@type":"person","name":"Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2010-10-01","publisher":{"@type":"Organization","name":"Am. J. Pathol., 2010-10-01;177(5):2379-86."},"author":{"@type":"person","name":"Tomlinson DC, Knowles MA"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2010-08-11","publisher":{"@type":"Organization","name":"PLoS ONE, 2010-08-11;5(8):e12101."},"author":{"@type":"person","name":"Roelandt P, Pauwelyn KA, Sancho-Bru P"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" FGFs, Wnts and BMPs mediate induction of VEGFR-2 (Quek-1) expression during avian somite development. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2007-03-01","publisher":{"@type":"Organization","name":"Dev. Biol., 2007-03-01;305(2):421-9."},"author":{"@type":"person","name":"Nimmagadda S, Geetha-Loganathan P, Scaal M, Christ B, Huang R"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Differentiation of ES cells into cerebellar neurons. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2007-02-09","publisher":{"@type":"Organization","name":"Proc. Natl. Acad. Sci. U.S.A., 2007-02-09;104(8):2997-3002."},"author":{"@type":"person","name":"Salero E, Hatten ME"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Cdx-Hox code controls competence for responding to Fgfs and retinoic acid in zebrafish neural tissue. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2006-11-01","publisher":{"@type":"Organization","name":"Development, 2006-11-01;133(23):4709-19."},"author":{"@type":"person","name":"Shimizu T, Bae YK, Hibi M"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2006-08-30","publisher":{"@type":"Organization","name":"Development, 2006-08-30;133(19):3787-96."},"author":{"@type":"person","name":"Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Expression of the short stature homeobox gene Shox is restricted by proximal and distal signals in chick limb buds and affects the length of skeletal elements. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2006-07-12","publisher":{"@type":"Organization","name":"Dev. Biol., 2006-07-12;298(2):585-96."},"author":{"@type":"person","name":"Tiecke E, Bangs F, Blaschke R, Farrell ER, Rappold G, Tickle C"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Embryonic stem cell-derived neuron models of Parkinson&apos;s disease exhibit delayed neuronal death. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2006-07-01","publisher":{"@type":"Organization","name":"J. Neurochem., 2006-07-01;98(1):45-56."},"author":{"@type":"person","name":"Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2006-06-12","publisher":{"@type":"Organization","name":"Dev. Biol., 2006-06-12;295(2):486-97."},"author":{"@type":"person","name":"Hutson MR, Zhang P, Stadt HA, Sato AK, Li YX, Burch J, Creazzo TL, Kirby ML"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2005-10-21","publisher":{"@type":"Organization","name":"Mol. Cell. Neurosci., 2005-10-21;31(2):251-62."},"author":{"@type":"person","name":"Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2005-07-29","publisher":{"@type":"Organization","name":"Proc. Natl. Acad. Sci. U.S.A., 2005-07-29;102(32):11343-8."},"author":{"@type":"person","name":"Delfini MC, Dubrulle J, Malapert P, Chal J, Pourquie O"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2005-06-23","publisher":{"@type":"Organization","name":"Development, 2005-06-23;132(15):3381-92."},"author":{"@type":"person","name":"Reversade B, Kuroda H, Lee H, Mays A, De Robertis EM"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Derivation of midbrain dopamine neurons from human embryonic stem cells. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2004-08-13","publisher":{"@type":"Organization","name":"Proc. Natl. Acad. Sci. U.S.A., 2004-08-13;101(34):12543-8."},"author":{"@type":"person","name":"Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2003-08-01","publisher":{"@type":"Organization","name":"Development, 2003-08-01;130(16):3821-9."},"author":{"@type":"person","name":"Wiellette EL, Sive H"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Specification of dorsal telencephalic character by sequential Wnt and FGF signaling. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2003-07-01","publisher":{"@type":"Organization","name":"Nat. Neurosci., 2003-07-01;6(7):701-7."},"author":{"@type":"person","name":"Gunhaga L, Marklund M, Sjodal M, Hsieh JC, Jessell TM, Edlund T"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2003-02-01","publisher":{"@type":"Organization","name":"Int. J. Dev. Biol., 2003-02-01;47(1):15-29."},"author":{"@type":"person","name":"Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2002-10-29","publisher":{"@type":"Organization","name":"Curr. Biol., 2002-10-29;12(21):1807-16."},"author":{"@type":"person","name":"Fischer A, Viebahn C, Blum M"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2002-10-01","publisher":{"@type":"Organization","name":"Development, 2002-10-01;129(19):4613-25."},"author":{"@type":"person","name":"Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN"}},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Regulation of avian cardiogenesis by Fgf8 signaling. ","isBasedOnUrl":"https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8","datePublished":"2002-04-01","publisher":{"@type":"Organization","name":"e0007247, 2002-04-01;129(8):1935-43."},"author":{"@type":"person","name":"Alsan BH, 2019, Schultheiss TM"}},{"@context":"http://schema.org","@type":"SiteNavigationElement","about":[{"@type":"Thing","url":"/support/sars-cov-research-resources","name":"COVID-19 Research Tools"},{"@type":"Thing","url":"/productsearch/novus","name":"Antibodies"},{"@type":"Thing","url":"/products/primary-antibodies","name":"Primary Antibodies"},{"@type":"Thing","url":"/conjugatedantibodies.html","name":"Conjugated Antibodies"},{"@type":"Thing","url":"/samplesize","name":"Sample Size Antibodies"},{"@type":"Thing","url":"/products/crispr-cas9-genetic-knockout-antibody-validation-reproducibility","name":"KO Validated Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/recombinant-monoclonals","name":"Recombinant Antibodies"},{"@type":"Thing","url":"/product-type/antibody-packs","name":"Antibody Sampler Packs"},{"@type":"Thing","url":"/product-type/antibody-pairs","name":"Antibody Pairs"},{"@type":"Thing","url":"/support/GeneralSecondaryAntibodies","name":"Secondary Antibodies"},{"@type":"Thing","url":"/products/isotype-controls","name":"Isotype Control Antibodies"},{"@type":"Thing","url":"/product-type/peptides-and-proteins","name":"Proteins and Peptides"},{"@type":"Thing","url":"/products/peptides-and-proteins","name":"Peptides & Proteins"},{"@type":"Thing","url":"/support/blocking-with-immunizing-peptide","name":"Blocking Peptides"},{"@type":"Thing","url":"/product-type/peptides-and-proteins%3Fapplications%3DBioactivity","name":"Biologically Active Proteins"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/lysates","name":"Lysates and Cell Lines"},{"@type":"Thing","url":"/product-type/lysates","name":"Lysates"},{"@type":"Thing","url":"/research-areas/stem-cells/stem-cell-lines.html","name":"Stem Cell Lines"},{"@type":"Thing","url":"/product-type/kits","name":"Kits"},{"@type":"Thing","url":"/Lightning-Link%20Antibody%20Labeling%20Kits","name":"Antibody Labeling Kits"},{"@type":"Thing","url":"/product-type/kits%3Fcategory%3DKits%26kit_type%3DChIP%2520Kit","name":"ChIP Kits"},{"@type":"Thing","url":"/products/elisa-kits","name":"ELISA Kits"},{"@type":"Thing","url":"/product-type/kits%3Fcategory%3DKits%26kit_type%3DFlow%2520Cytometry%2520Kit","name":"Flow Cytometry Kits"},{"@type":"Thing","url":"/product-type/support-products%3Fcategory%3DSupport%2520Products%26applications%3DLigand%2520Activation","name":"Activators and Inhibitors"},{"@type":"Thing","url":"/product-type/inhibitors","name":"Inhibitors"},{"@type":"Thing","url":"/product-type/support-products%3Fcategory%3DSupport%2520Products%26applications%3DLigand%2520Activation","name":"Activators"},{"@type":"Thing","url":"/product-type/support-products","name":"Support Products"},{"@type":"Thing","url":"/research-topics/cell-biology/exosome-isolation-and-detection","name":"Exosome Isolation"},{"@type":"Thing","url":"/products/flow-cytometry-quality-control-beads","name":"Flow Cytometry Beads"},{"@type":"Thing","url":"/control-slides","name":"IHC Tissue Slides"},{"@type":"Thing","url":"/tissue-microarrays","name":"IHC Microarrays"},{"@type":"Thing","url":"/search%3Fkeywords%3Drunblue","name":"Western Blot Gels & Buffers"},{"@type":"Thing","url":"/product-type/wb-membranes","name":"Western Blot Membranes"},{"@type":"Thing","url":"/product-type/support-products","name":"All Support Products"},{"@type":"Thing","url":"/support/bulk-and-custom.html","name":"Bulk and Custom"},{"@type":"Thing","url":"/support.html","name":"Resources"},{"@type":"Thing","url":"/support/support-by-application.html","name":"Protocols"},{"@type":"Thing","url":"/support/video-protocols","name":"Video Protocols"},{"@type":"Thing","url":"/support/troubleshooting","name":"Troubleshooting Guides"},{"@type":"Thing","url":"/mailing-list","name":"Posters and Literature"},{"@type":"Thing","url":"/support/handbooks-and-guides","name":"Handbooks and Guides"},{"@type":"Thing","url":"/resources/calculators","name":"Calculators"},{"@type":"Thing","url":"/support/faqs.html","name":"FAQs"},{"@type":"Thing","url":"/antibody-news","name":"Blogs"},{"@type":"Thing","url":"/all-diseases.html","name":"Diseases"},{"@type":"Thing","url":"/whitepapers.html","name":"Whitepapers"},{"@type":"Thing","url":"/webform/help-finding-antibodies","name":"Antibody Concierge"},{"@type":"Thing","url":"/webinar","name":"Webinars"},{"@type":"Thing","url":"/research-tools.html","name":"Tools"},{"@type":"Thing","url":"/spectraviewer","name":"Spectra Viewer"},{"@type":"Thing","url":"/novusknowsflow.html","name":"Flow Cytometry Panel Builder"},{"@type":"Thing","url":"/application","name":"Application"},{"@type":"Thing","url":"/application/elisa","name":"ELISA"},{"@type":"Thing","url":"/application/flow-cytometry","name":"Flow Cytometry"},{"@type":"Thing","url":"https://www.novusbio.com/products/antibodies-cytof","name":"Mass Cytometry (CyTOF)"},{"@type":"Thing","url":"/application/icc","name":"ICC"},{"@type":"Thing","url":"/application/ihc","name":"IHC"},{"@type":"Thing","url":"/application/western-blotting","name":"Western Blotting"},{"@type":"Thing","url":"/interviews","name":"Interviews"},{"@type":"Thing","url":"/faculty/faculty-interviews","name":"Faculty"},{"@type":"Thing","url":"/postdoc/postdoc-interviews","name":"Postdoc"},{"@type":"Thing","url":"/research-areas.html","name":"By Research Area"},{"@type":"Thing","url":"/apoptosis-pathway","name":"Apoptosis"},{"@type":"Thing","url":"/autophagy-pathway","name":"Autophagy"},{"@type":"Thing","url":"/research-areas/cancer","name":"Cancer"},{"@type":"Thing","url":"/research-areas/cell-biology","name":"Cell Biology"},{"@type":"Thing","url":"/research-areas/cellular-markers","name":"Cellular Markers"},{"@type":"Thing","url":"/research-areas/epigenetics","name":"Epigenetics"},{"@type":"Thing","url":"/research-areas/epitope-tags","name":"Epitope Tags"},{"@type":"Thing","url":"/research-areas/cell-biology/Exosome-research-tools","name":"Exosomes Research"},{"@type":"Thing","url":"/research-areas/hypoxia","name":"Hypoxia"},{"@type":"Thing","url":"/research-areas/immunology","name":"Immunology"},{"@type":"Thing","url":"/research-areas/microbiology","name":"Microbiology"},{"@type":"Thing","url":"/research-areas/neuroscience","name":"Neuroscience"},{"@type":"Thing","url":"/research-areas/stem-cells","name":"Stem Cells"},{"@type":"Thing","url":"/pathwaypages.html","name":"By Pathway"},{"@type":"Thing","url":"/akt-signaling-pathway","name":"AKT "},{"@type":"Thing","url":"/mapkerkpathway.html","name":"ERK1/2/5 Pathway"},{"@type":"Thing","url":"/hedgehogpathway.html","name":"Hedgehog"},{"@type":"Thing","url":"/hippo-pathway.html","name":"Hippo"},{"@type":"Thing","url":"/jnk-signaling-pathway","name":"JNK Pathway"},{"@type":"Thing","url":"/mtor-pathway","name":"mTOR"},{"@type":"Thing","url":"/necroptosis-pathway","name":"Necroptosis"},{"@type":"Thing","url":"/nfkbpathway","name":"NFKB Signaling"},{"@type":"Thing","url":"/p38mapkpathway.html","name":"p38 Signaling"},{"@type":"Thing","url":"/tgfbetapathway","name":"TGF Beta"},{"@type":"Thing","url":"/toll-like-receptors","name":"TLR"},{"@type":"Thing","url":"/programs.html","name":"Customer Care"},{"@type":"Thing","url":"/guarantee","name":"100% Guarantee"},{"@type":"Thing","url":"/support/innovators-reward.html","name":"Risk Free Testing"},{"@type":"Thing","url":"/about/rewards.html","name":"Novus Rewards Program"},{"@type":"Thing","url":"/publications","name":"Publication Rewards Program"},{"@type":"Thing","url":"/newlab.html","name":"New Lab Discount"},{"@type":"Thing","url":"/scholarship-program.html","name":"Scholarship"},{"@type":"Thing","url":"/travelgrant.html","name":"Travel Grants"},{"@type":"Thing","url":"/products/promotions","name":"Promotions"},{"@type":"Thing","url":"/about.html","name":"About us"},{"@type":"Thing","url":"https://www.bio-techne.com/about/careers","name":"Careers"},{"@type":"Thing","url":"/about/collaborations.html","name":"Collaborations"},{"@type":"Thing","url":"/about/events","name":"Events"},{"@type":"Thing","url":"/about/novus-story.html","name":"Novus Story"},{"@type":"Thing","url":"/about/novus-team.html","name":"Our Team"},{"@type":"Thing","url":"/about/novus-philanthropy.html","name":"Philanthropy"},{"@type":"Thing","url":"/about/press-release.html","name":"Press Releases"},{"@type":"Thing","url":"/why-choose-novus.html","name":"Why choose Novus"},{"@type":"Thing","url":"/about/contact-us.html","name":"Contact Us"},{"@type":"Thing","url":"/about/contact-us.html","name":"Customer Service"},{"@type":"Thing","url":"/novus-distributors/list","name":"Distributors"},{"@type":"Thing","url":"/support/technical-support.html","name":"Technical Support"}]},{"@context":"http://schema.org","@type":"WPFooter","about":[{"@type":"Thing","url":"https://www.novusbio.com/productsearch/novus","name":"Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/secondary-antibodies","name":"Secondary Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/isotype-controls","name":"Isotype Controls"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/peptides-and-proteins","name":"Proteins and Peptides"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/elisa-kits","name":"ELISA Kits"},{"@type":"Thing","url":"https://www.novusbio.com/samplesize","name":"Sample Size"},{"@type":"Thing","url":"https://www.novusbio.comhttps://www.novusbio.com/new-product-information-page.html","name":"New Products"},{"@type":"Thing","url":"https://www.novusbio.com/about.html","name":"About Us"},{"@type":"Thing","url":"https://www.novusbio.comhttps://www.bio-techne.com/about/careers","name":"Careers"},{"@type":"Thing","url":"https://www.novusbio.com/guarantee","name":"Novus Guarantee"},{"@type":"Thing","url":"https://www.novusbio.com/about/contact-us.html","name":"Contact Us"},{"@type":"Thing","url":"https://www.novusbio.com/about/novus-team.html","name":"Our Team"},{"@type":"Thing","url":"https://www.novusbio.com/support/customer-service/privacy-policy.html","name":"Privacy Policy"},{"@type":"Thing","url":"https://www.novusbio.com/novus-bio-sitemap.html","name":"Sitemap"},{"@type":"Thing","url":"https://www.novusbio.com/about/contact-us.html","name":"Contact Us"},{"@type":"Thing","url":"https://www.novusbio.com/support/customer-service/terms.html","name":"Terms & Conditions"},{"@type":"Thing","url":"https://www.novusbio.com/support/technical-support.html","name":"Technical Support"},{"@type":"Thing","url":"https://www.novusbio.com/support/faqs.html","name":"FAQs"},{"@type":"Thing","url":"https://www.novusbio.com/webform/help-finding-antibodies","name":"Help Finding Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/support/support-by-application.html","name":"Protocols"}]},{"@context":"http://schema.org","@type":"WebPage","breadcrumb":{"@context":"http://schema.org","@type":"BreadcrumbList","itemListElement":[{"@context":"http://schema.org","@type":"ListItem","position":1,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.novusbio.com/","name":"Home"}},{"@context":"http://schema.org","@type":"ListItem","position":2,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.novusbio.com/common-name/fgf-8","name":"FGF-8"}},{"@context":"http://schema.org","@type":"ListItem","position":3,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.novusbio.com/proteins/fgf-8","name":"FGF-8 Proteins"}}]},"potentialaction":{"query":""}}]</script> <meta name="generator" content="Drupal 7 (https://www.drupal.org)" /> <link rel="shortlink" href="https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8" /> <meta property="og:site_name" content="Novus Biologicals" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.novusbio.com/products/recombinant-human-mouse-fgf-8b-protein_423-f8" /> <meta property="og:title" content="Recombinant Human/Mouse FGF-8b Protein" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_LyQQziAp-Ie-zmhrx1RDdqrlziy3o8gvzDqRXCb00hg.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_PKXTPBTTuSBPF7NSrNT2twmpZB05BY2cuOTz_4_8ORI.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_epQTvxkLlfWLGSq94lW04RlDEK26840QgzyS2d_R_fw.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_9eZvvH8xiAz18sT-zmuTZfYzHdV0O-FbSNe_tS771K4.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_8-zvMULc0G5JczOUIWkZin0svexCP7R5pWo6msP_YwM.css" media="all" /> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_VUlliwzd-_is1_ryJskaiFlvPtaBpYuWsDxU6fMyUEk.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_c8LbWbHV1txem3q8oAzuadnL-HiBShaQH_WRviNqT_g.js"></script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- jQuery.migrateMute=true;jQuery.migrateTrace=false; //--><!]]> </script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_4newT8cBOK9auTS1LAR6RL1VYq1INsyOKwxSb1E2BPI.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_L-CbsMNxXdHxvTeHTLjdXGdqfQk0RETDYk8CikUPuJI.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_4Vv8GAuPg4M6GWetVxgFDPNPYfVcP37nnmzoZnsPOj8.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_V5Fwoup1DkxxL-Rm-7is5QWj_MZhigWTY27_fmKn7S4.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_2jDjItK5kn1HYGdOJItscmD-MBTGKiaxNmzYli64GOs.js"></script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- var dataLayer = dataLayer || []; dataLayer.push({"email": ""}); dataLayer.push({'PageType': 'ProductPage', 'ProductID': '423-F8'}); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- var dataLayer = dataLayer || [] dataLayer.push({"event":"userRole","userRole":"anonymous user"}); dataLayer.push({"event":"productDetail","ecommerce":{"currencyCode":"USD","detail":{"actionField":{"list":""},"products":[{"id":"423-F8","name":"Recombinant Human\/Mouse FGF-8b Protein","category":"Peptides and Proteins","brand":"rnd","price":318,"variant":null,"dimension28":null,"dimension29":null}]}}}); dataLayer.push({"event":"productImpressions","ecommerce":{"currencyCode":"USD","impressions":[{"id":"464-SH","name":"Sonic Hedgehog\/Shh [Unconjugated]","position":1,"list":""},{"id":"314-BP","name":"BMP-4 [Unconjugated]","position":2,"list":""},{"id":"235-F4","name":"FGF-4 [Unconjugated]","position":3,"list":""},{"id":"233-FB","name":"FGF basic\/FGF2\/bFGF [Unconjugated]","position":4,"list":""},{"id":"345-FG","name":"FGF-10 [Unconjugated]","position":5,"list":""},{"id":"NB600-1287","name":"FGFR1 Antibody (M19B2) - BSA Free","position":6,"list":""},{"id":"H00002263-M01","name":"FGFR2 Antibody (1G3)","position":7,"list":""},{"id":"1206-F3","name":"FGF-3 [Unconjugated]","position":8,"list":""},{"id":"AF1979","name":"Otx2 Antibody [Unconjugated]","position":9,"list":""},{"id":"AF3364","name":"Pax2 Antibody [Unconjugated]","position":10,"list":""},{"id":"355-BM","name":"BMP-2 [Unconjugated]","position":11,"list":""},{"id":"NBP1-51575","name":"Wnt-1 Antibody (10C8) - BSA Free","position":12,"list":""},{"id":"AF5045","name":"MSX1 Antibody [Unconjugated]","position":13,"list":""},{"id":"AF232","name":"FGF acidic\/FGF1 Antibody [Unconjugated]","position":14,"list":""},{"id":"NB100-55393","name":"GBX2 Antibody","position":15,"list":""},{"id":"NBP2-20486","name":"SS18L1 Antibody","position":16,"list":""},{"id":"MAB319","name":"FGF-17 Antibody (121630)","position":17,"list":""},{"id":"NB300-109","name":"Tyrosine Hydroxylase Antibody","position":18,"list":""},{"id":"H00002019-M04","name":"EN1\/Engrailed 1 Antibody (3H2)","position":19,"list":""},{"id":"423-F8","name":"Recombinant Human\/Mouse FGF-8b Protein","position":20,"list":""},{"id":"NB300-109","name":"Tyrosine Hydroxylase Antibody","position":21,"list":""}]}}); //--><!]]> </script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_MrgubHtdOA1nVcjDTR4s-m0ya_aIvugR02VlGxCGGDw.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_sNIdssRhxhJxJxAR2Pduc4_PqOXIKZf2m8g4hyLSJ8s.js"></script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- jQuery.extend(Drupal.settings, {"basePath":"\/","pathPrefix":"","setHasJsCookie":0,"ajaxPageState":{"theme":"novus","theme_token":"04r-qFJKtAD_UTiaWsvv1grA0JvCV7peQVsoM8azJb4","js":{"0":1,"public:\/\/google_tag\/google_tag.script.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/jquery\/3.5\/jquery.min.js":1,"1":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/jquery-migrate\/3\/jquery-migrate.min.js":1,"misc\/jquery-extend-3.4.0.js":1,"misc\/jquery-html-prefilter-3.5.0-backport.js":1,"misc\/jquery.once.js":1,"misc\/drupal.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_cookie.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jQuery_cycle2.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/colorbox.1.5.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/shockwave_flash.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_datatables.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_tablesorter.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_hoverintent.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_lazyload.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/modernizr.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/underscore.js":1,"sites\/novusbio.com\/themes\/novus\/js\/fix_script.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.core.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.widget.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.effect.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.effect-highlight.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.button.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.mouse.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.draggable.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.position.min.js":1,"misc\/ui\/jquery.ui.position-1.13.0-backport.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.resizable.min.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.dialog.min.js":1,"misc\/ui\/jquery.ui.dialog-1.13.0-backport.js":1,"sites\/novusbio.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.tooltip.min.js":1,"sites\/all\/modules\/enterprise-tech\/et_onecall\/js\/et_onecall.js":1,"sites\/all\/modules\/contrib\/fields\/entityreference\/js\/entityreference.js":1,"sites\/all\/modules\/et_commerce\/et_commerce_extras\/modules\/et_cartdropdown\/et_cartdropdown.js":1,"sites\/all\/modules\/enterprise-tech\/et_internationalization\/js\/et_internationalization.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jQuery_et.js":1,"sites\/all\/modules\/et_commerce\/et_quickorder\/et_quickorder.js":1,"sites\/all\/modules\/contrib\/marketo_ma\/js\/marketo_ma.js":1,"sites\/novusbio.com\/modules\/custom\/novus_shipping\/js\/novus_shipping.js":1,"sites\/all\/libraries\/DOMPurify\/purify.min.js":1,"sites\/all\/modules\/contrib\/colorbox\/js\/colorbox.js":1,"sites\/all\/modules\/contrib\/colorbox\/styles\/stockholmsyndrome\/colorbox_style.js":1,"sites\/all\/modules\/enterprise-tech\/et_cookie_policy\/js\/et_cookie_policy.js":1,"sites\/all\/modules\/enterprise-tech\/et_internationalization\/js\/novus_distributors.js":1,"sites\/all\/modules\/enterprise-tech\/et_search\/json_viewer\/js\/jsonviewer.js":1,"sites\/all\/modules\/enterprise-tech\/et_searchbar_autocomplete\/js\/et_searchbar_autocomplete.js":1,"sites\/all\/modules\/enterprise-tech\/et_datasheets\/js\/novus_datasheets.js":1,"misc\/tableheader.js":1,"sites\/all\/modules\/enterprise-tech\/et_calculator\/js\/et_calculator.js":1,"sites\/all\/modules\/enterprise-tech\/et_main_menu\/js\/main_menu.js":1,"sites\/all\/modules\/enterprise-tech\/et_searchbar\/js\/et_searchbar.js":1,"sites\/all\/modules\/enterprise-tech\/et_combined_seo\/js\/et_combined_seo.js":1,"2":1,"3":1,"sites\/all\/modules\/enterprise-tech\/et_messages\/et_messages.js":1,"sites\/novusbio.com\/themes\/novus\/js\/novus.js":1,"sites\/novusbio.com\/themes\/novus\/css\/colorbox\/colorbox_style.js":1},"css":{"modules\/system\/system.base.css":1,"modules\/system\/system.menus.css":1,"modules\/system\/system.messages.css":1,"modules\/system\/system.theme.css":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/css\/datatables.css":1,"misc\/ui\/jquery.ui.core.css":1,"misc\/ui\/jquery.ui.theme.css":1,"misc\/ui\/jquery.ui.button.css":1,"misc\/ui\/jquery.ui.resizable.css":1,"misc\/ui\/jquery.ui.dialog.css":1,"misc\/ui\/jquery.ui.tooltip.css":1,"modules\/comment\/comment.css":1,"sites\/all\/modules\/enterprise-tech\/et_internationalization\/css\/et_internationalization.css":1,"sites\/all\/modules\/enterprise-tech\/et_product_page_promo\/css\/et_product_page_promo.css":1,"sites\/all\/modules\/et_commerce\/et_quickorder\/css\/et_quickorder.css":1,"sites\/all\/modules\/enterprise-tech\/et_searchbar_autocomplete\/css\/et_searchbar_autocomplete.css":1,"modules\/field\/theme\/field.css":1,"modules\/node\/node.css":1,"sites\/novusbio.com\/modules\/custom\/novus_catalogrequest\/css\/novus_catalogrequest.css":1,"sites\/novusbio.com\/modules\/custom\/novus_shipping\/css\/novus_shipping.css":1,"sites\/novusbio.com\/modules\/custom\/novus_user_profile\/css\/novus_user_profile.css":1,"modules\/user\/user.css":1,"sites\/all\/modules\/contrib\/views\/css\/views.css":1,"sites\/all\/modules\/contrib\/userInterface\/ckeditor\/css\/ckeditor.css":1,"sites\/all\/modules\/contrib\/colorbox\/styles\/stockholmsyndrome\/colorbox_style.css":1,"sites\/all\/modules\/contrib\/ctools\/css\/ctools.css":1,"sites\/all\/modules\/enterprise-tech\/et_messages\/et_messages_admin.css":1,"sites\/all\/modules\/enterprise-tech\/et_messages\/css\/novus-transfer-cart.css":1,"sites\/all\/modules\/enterprise-tech\/et_datasheets\/css\/novus_datasheets.css":1,"sites\/all\/modules\/enterprise-tech\/et_datasheet_adzones\/css\/et_datasheet_adzones.css":1,"sites\/all\/modules\/enterprise-tech\/bt_brands_bar\/css\/bt_brands_bar.css":1,"sites\/all\/modules\/et_commerce\/et_commerce_extras\/modules\/et_cartdropdown\/css\/et_cartdropdown.css":1,"sites\/all\/modules\/enterprise-tech\/et_messages\/skins\/default\/et_messages.css":1,"sites\/all\/modules\/enterprise-tech\/et_cookie_policy\/css\/default_policy.css":1,"sites\/novusbio.com\/themes\/novus\/css\/novus.css":1,"sites\/novusbio.com\/themes\/novus\/css\/960_16_col.css":1,"sites\/novusbio.com\/themes\/novus\/css\/960_12_col.css":1,"sites\/novusbio.com\/themes\/novus\/css\/better_messages.css":1,"sites\/novusbio.com\/themes\/novus\/css\/colorbox\/colorbox_style.css":1}},"colorbox":{"opacity":"0.85","current":"{current} of {total}","previous":"\u00ab Prev","next":"Next \u00bb","close":"Close","maxWidth":"98%","maxHeight":"98%","fixed":true,"mobiledetect":true,"mobiledevicewidth":"480px","file_public_path":"\/sites\/novusbio.com\/files","specificPagesDefaultValue":"admin*\nimagebrowser*\nimg_assist*\nimce*\nnode\/add\/*\nnode\/*\/edit\nprint\/*\nprintpdf\/*\nsystem\/ajax\nsystem\/ajax\/*"},"country_name":"United States","et_internationalization":{"social":" \u003Ctable\u003E\n \u003Ctr\u003E\n \u003Ctd colspan=\u00222\u0022\u003E\n \u003Cp\u003E\n \u003Ca href=\u0022\/newsletter-signup\u0022 id=\u0022footer_newsletter_button\u0022 title=\u0022Newsletter Signup\u0022\u003E\n Newsletter Signup\n \u003C\/a\u003E\n \u003C\/p\u003E\n \u003C\/td\u003E\n \u003C\/tr\u003E\n \u003Ctr\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.facebook.com\/NovusBiologicals\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022fp_social_facebook\u0022\u003E\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.facebook.com\/NovusBiologicals\u0022 target=\u0022_blank\u0022\u003EFind us on Facebook\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003C\/tr\u003E\n \u003Ctr\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/twitter.com\/novusbio\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022fp_social_twitter social\u0022\u003E\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/twitter.com\/novusbio\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022social_text\u0022\u003EFollow us on Twitter\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003C\/tr\u003E\n \u003Ctr\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.youtube.com\/user\/NovusBiologicals\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022fp_social_youtube social\u0022\u003E\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.youtube.com\/user\/NovusBiologicals\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022social_text\u0022\u003EWatch us on YouTube\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003C\/tr\u003E\n \u003Ctr\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.linkedin.com\/company\/novus-biologicals-llc\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022fp_social_linkedin social\u0022\u003E\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.linkedin.com\/company\/novus-biologicals-llc\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022social_text\u0022\u003EConnect with us on LinkedIn\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003C\/tr\u003E\n \u003Ctr\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.instagram.com\/novusbiologicals\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022fp_social_instagram social\u0022\u003E\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003Ctd\u003E\u003Ca href=\u0022\/\/www.instagram.com\/novusbiologicals\u0022 target=\u0022_blank\u0022\u003E\u003Cdiv class=\u0022social_text\u0022\u003EConnect with us on Instagram\u003C\/div\u003E\u003C\/a\u003E\u003C\/td\u003E\n \u003C\/tr\u003E\n \u003C\/table\u003E","distphone":""},"et_onecall":{"active":"true"},"et_searchbar":{"min_chars":3},"urlIsAjaxTrusted":{"\/products\/recombinant-human-mouse-fgf-8b-protein_423-f8":true},"etMessages":{"position":"center","vertical":0,"horizontal":10,"fixed":1,"width":"400px","autoclose":0,"opendelay":0.29999999999999999,"disable_autoclose":0,"show_countdown":1,"hover_autoclose":1,"popin":{"effect":"fadeIn","duration":"slow"},"popout":{"effect":"fadeOut","duration":"slow"},"0":"enable_novus_cart_transfer","1":"obt_transfer_cart_endpoint","enable_novus_cart_transfer":0,"obt_transfer_cart_endpoint":"https:\/\/www.bio-techne.com\/commerce\/novuscart"}}); //--><!]]> </script> <link rel="shortcut icon" type="image/ico" href="//images.novusbio.com/design/faviconNew.ico"/> <meta name="yandex-verification" content="e7c24419f013b549"/> </head> <body class="html not-front not-logged-in no-sidebars page-products page-products-recombinant-human-mouse-fgf-8b-protein-423-f8" > <!-- Google Tag Manager (noscript) --> <noscript> <iframe src="https://www.googletagmanager.com/ns.html?id=GTM-52KXLL" height="0" width="0" style="display:none;visibility:hidden"></iframe> </noscript> <!-- End Google Tag Manager (noscript) --> <div id="skip-link"> <a href="#main-content" class="element-invisible element-focusable">Skip to main content</a> </div> <noscript aria-hidden="true"><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-52KXLL" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript><!--Pricing notice container--> <!--Pricing notice container end--> <div class="region region-bt-brands-bar"> <div id="block-bt-brands-bar-bt-brands-bar" class="block block-bt-brands-bar"> <div class="content"> <div id="bt_brands_bar"> <div class="container_16"> <div style="margin-left: 0px; margin-right: 0px; width:960px;zoom:1;word-wrap:break-word;"> <ul> <li><a href="https://www.bio-techne.com" rel="noopener noreferrer" target="_blank" aria-label="Bio-Techne"><div class="brandsSprite_biotechne"></div></a></li><li><a href="https://www.rndsystems.com" rel="noopener noreferrer" target="_blank" aria-label="R&D Systems"><div class="brandsSprite_rndsystems"></div></a></li><li class="active"><div class="brandsSprite_novusbio_color"></div></li><li><a href="https://www.tocris.com" rel="noopener noreferrer" target="_blank" aria-label="Tocris Bioscience"><div class="brandsSprite_tocris"></div></a></li><li><a href="https://www.bio-techne.com/brands/proteinsimple" rel="noopener noreferrer" target="_blank" aria-label="ProteinSimple"><div class="brandsSprite_proteinsimple"></div></a></li><li><a href="https://www.biospacific.com" rel="noopener noreferrer" target="_blank" aria-label="BiosPacific"><div class="brandsSprite_biospacific"></div></a></li><li><a href="https://www.cliniqa.com" rel="noopener noreferrer" target="_blank" aria-label="Cliniqa"><div class="brandsSprite_cliniqa"></div></a></li><li><a href="https://acdbio.com/ " rel="noopener noreferrer" target="_blank" aria-label="ACD"><div class="brandsSprite_acd"></div></a></li><li><a href="https://www.rndheme.com" rel="noopener noreferrer" target="_blank" aria-label="R&D Heme"><div class="brandsSprite_rndheme"></div></a></li> </ul> </div> </div> </div> </div> </div> <div id="block-et-cookie-policy-cookie-policy" class="block block-et-cookie-policy"> <div class="content"> <div></div> </div> </div> </div> <div class="overlay"></div> <div id="header"> <div class="bluewide_wrapper"> <div class="container_16"> <div class="grid_16"> <div id="top_bar"> <div class="region region-top-left-bar"> <div id="block-et-internationalization-novus-dist-short" class="block block-et-internationalization"> <div class="content"> <div id="top_bar_support_info"><noscript>Support: 1-888-506-6887</noscript></div> </div> </div> </div> <div id="top_bar_novus"> <div class="region region-top-right-bar"> <div id="block-et-quickorder-et-quickorder" class="block block-et-quickorder"> <div class="content"> <div id="quickOrder_topbar">Quick Order &nbsp;<div class="fp_quickorder_arrow"></div> <div id="quickOrder_dropdown"> <p class="quickOrder_disabled">Quick order is disabled in your country. Please contact Customer Service if you have questions.</p></div> </div> </div> </div> <div id="block-et-internationalization-country-dropdown" class="block block-et-internationalization"> <div class="content"> <div id="internationalization_country_select"> <div class="internationalization_drop"></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="content-wrapper" class="container_16"> <div class="grid_4"> <div id="logo"> <a href="/"><img src="//images.novusbio.com/design/novus_color_RGB_small.png" alt="Novus Biologicals Logo"></a> </div> </div> <div class="grid_12"> <div class="region region-login-area"> <div id="block-et-internationalization-sign-in" class="block block-et-internationalization"> <div class="content"> <div id="sign_in"><a href="/user/login" rel="nofollow"><noscript>Account</noscript></a></div> </div> </div> </div> <div class="search_form_container"> <div class="region region-search-bar"> <div id="block-et-searchbar-et-searchbar-bar" class="block block-et-searchbar"> <div class="content"> <div class="et_searchbar_wrapper"> <form name="et_searchbar" method="GET" action="/search" class="search_form"><div class="et_searchbar"> <input autocomplete="off" name="keywords" type="text" class="et_searchbar_wide et_searchbar_default" value="" placeholder="Enter Catalog #, Protein, or Keywords." data-default="" /><input type="submit" value="search" class="fp_mag_glass_wideSearch"></div></form><div class="et_spinner_small et_searchbar_spinner"></div> </div> </div> </div> </div> <!--<form id="search-form" method="get" action="/search" onsubmit="return setClearSearchText('submit');" > <input name="keywords" id="search-string" type="text" placeholder="Enter Catalog #, Protein, or Keywords." class="hide_spinner" /> <input type="submit" value="search" class="search_button" /> </form>--> </div> </div> <div class="clear"></div> </div> </div> <div class="bluewide_wrapper"> <div class="container_16"> <div class="grid_16" id="main_menu"> <div class="region region-header"> <div id="block-et-main-menu-et-main-menu-block" class="block block-et-main-menu"> <div class="content"> <div id="main_menu_wrapper"> <ul id="small_menu"> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_products" class="menu_drop"> <div class="mm_menu"><ul class="menu"><li class="first expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first leaf"><a href="/support/sars-cov-research-resources" title="">COVID-19 Research Tools</a></li> <li class="expanded"><a href="/productsearch/novus" title="">Antibodies</a><ul class="menu"><li class="first expanded"><a href="/products/primary-antibodies" title="">Primary Antibodies</a><ul class="menu"><li class="first leaf"><a href="/conjugatedantibodies.html" title="">Conjugated Antibodies</a></li> <li class="leaf"><a href="/samplesize" title="">Sample Size Antibodies</a></li> <li class="leaf"><a href="/products/crispr-cas9-genetic-knockout-antibody-validation-reproducibility" title="">KO Validated Antibodies</a></li> <li class="leaf"><a href="https://www.novusbio.com/recombinant-monoclonals" title="">Recombinant Antibodies</a></li> <li class="leaf"><a href="/product-type/antibody-packs" title="">Antibody Sampler Packs</a></li> <li class="last leaf"><a href="/product-type/antibody-pairs" title="">Antibody Pairs</a></li> </ul></li> <li class="leaf"><a href="/support/GeneralSecondaryAntibodies" title="">Secondary Antibodies</a></li> <li class="last leaf"><a href="/products/isotype-controls" title="">Isotype Control Antibodies</a></li> </ul></li> <li class="expanded"><a href="/product-type/peptides-and-proteins" title="">Proteins and Peptides</a><ul class="menu"><li class="first leaf"><a href="/products/peptides-and-proteins" title="">Peptides &amp; Proteins</a></li> <li class="leaf"><a href="/support/blocking-with-immunizing-peptide" title="">Blocking Peptides</a></li> <li class="last leaf"><a href="/product-type/peptides-and-proteins?applications=Bioactivity" title="">Biologically Active Proteins</a></li> </ul></li> <li class="last expanded"><a href="https://www.novusbio.com/product-type/lysates" title="">Lysates and Cell Lines</a><ul class="menu"><li class="first leaf"><a href="/product-type/lysates" title="">Lysates</a></li> <li class="last leaf"><a href="/research-areas/stem-cells/stem-cell-lines.html" title="">Stem Cell Lines</a></li> </ul></li> </ul></li> <li class="last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first expanded"><a href="/product-type/kits" title="">Kits</a><ul class="menu"><li class="first leaf"><a href="/Lightning-Link%20Antibody%20Labeling%20Kits" title="">Antibody Labeling Kits</a></li> <li class="leaf"><a href="/product-type/kits?category=Kits&amp;kit_type=ChIP%20Kit" title="">ChIP Kits</a></li> <li class="leaf"><a href="/products/elisa-kits" title="">ELISA Kits</a></li> <li class="last leaf"><a href="/product-type/kits?category=Kits&amp;kit_type=Flow%20Cytometry%20Kit" title="">Flow Cytometry Kits</a></li> </ul></li> <li class="expanded"><a href="/product-type/support-products?category=Support%20Products&amp;applications=Ligand%20Activation" title="">Activators and Inhibitors</a><ul class="menu"><li class="first leaf"><a href="/product-type/inhibitors" title="">Inhibitors</a></li> <li class="last leaf"><a href="/product-type/support-products?category=Support%20Products&amp;applications=Ligand%20Activation" title="">Activators</a></li> </ul></li> <li class="expanded"><a href="/product-type/support-products" title="">Support Products</a><ul class="menu"><li class="first leaf"><a href="/research-topics/cell-biology/exosome-isolation-and-detection" title="Exosome Isolation and Detection Tools">Exosome Isolation</a></li> <li class="leaf"><a href="/products/flow-cytometry-quality-control-beads" title="Flow Cytometry Calibration, Compensation and Cell Counting Beads">Flow Cytometry Beads</a></li> <li class="leaf"><a href="/control-slides" title="">IHC Tissue Slides</a></li> <li class="leaf"><a href="/tissue-microarrays" title="">IHC Microarrays</a></li> <li class="leaf"><a href="/search?keywords=runblue" title="">Western Blot Gels &amp; Buffers</a></li> <li class="leaf"><a href="/product-type/wb-membranes" title="">Western Blot Membranes</a></li> <li class="last leaf"><a href="/product-type/support-products" title="">All Support Products</a></li> </ul></li> <li class="last leaf"><a href="/support/bulk-and-custom.html" title="">Bulk and Custom</a></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/search?keywords=novus" class="main_menu_parent_link">Products</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_support" class="menu_drop"> <div class="mm_menu"><a href="/support/support-by-application.html"><div class="link_button link_protocols_button">Our Protocols</div></a><ul class="menu"><li class="first expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/support.html" title="">Resources</a><ul class="menu"><li class="first leaf"><a href="/support/support-by-application.html" title="">Protocols</a></li> <li class="leaf"><a href="/support/video-protocols" title="">Video Protocols</a></li> <li class="leaf"><a href="/support/troubleshooting" title="">Troubleshooting Guides</a></li> <li class="leaf"><a href="/mailing-list" title="">Posters and Literature</a></li> <li class="leaf"><a href="/support/handbooks-and-guides" title="">Handbooks and Guides</a></li> <li class="leaf"><a href="/resources/calculators" title="">Calculators</a></li> <li class="leaf"><a href="/support/faqs.html" title="">FAQs</a></li> <li class="leaf"><a href="/antibody-news" title="">Blogs</a></li> <li class="leaf"><a href="/all-diseases.html" title="">Diseases</a></li> <li class="leaf"><a href="/whitepapers.html" title="">Whitepapers</a></li> <li class="leaf"><a href="/webform/help-finding-antibodies" title="">Antibody Concierge</a></li> <li class="last leaf"><a href="/webinar" title="">Webinars</a></li> </ul></li> </ul></li> <li class="last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first expanded"><a href="/research-tools.html" title="">Tools</a><ul class="menu"><li class="first leaf"><a href="/spectraviewer" title="">Spectra Viewer</a></li> <li class="last leaf"><a href="/novusknowsflow.html" title="">Flow Cytometry Panel Builder</a></li> </ul></li> <li class="expanded"><a href="/application" title="">Application</a><ul class="menu"><li class="first leaf"><a href="/application/elisa" title="">ELISA</a></li> <li class="leaf"><a href="/application/flow-cytometry" title="">Flow Cytometry</a></li> <li class="leaf"><a href="https://www.novusbio.com/products/antibodies-cytof" title="">Mass Cytometry (CyTOF)</a></li> <li class="leaf"><a href="/application/icc" title="">ICC</a></li> <li class="leaf"><a href="/application/ihc" title="">IHC</a></li> <li class="last leaf"><a href="/application/western-blotting" title="">Western Blotting</a></li> </ul></li> <li class="last expanded"><a href="/interviews" title="">Interviews</a><ul class="menu"><li class="first leaf"><a href="/faculty/faculty-interviews" title="">Faculty</a></li> <li class="last leaf"><a href="/postdoc/postdoc-interviews" title="">Postdoc</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/support.html" class="main_menu_parent_link">Resources</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_ra" class="menu_drop"> <div class="mm_menu"><a href="/pathwaypages.html"><div class="link_button">View Pathways</div></a><ul class="menu"><li class="first expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/research-areas.html" title="">By Research Area</a><ul class="menu"><li class="first leaf"><a href="/research-areas/apoptosis" title="">Apoptosis</a></li> <li class="leaf"><a href="/research-areas/autophagy" title="">Autophagy</a></li> <li class="leaf"><a href="/research-areas/cancer" title="">Cancer</a></li> <li class="leaf"><a href="/research-areas/cell-biology" title="">Cell Biology</a></li> <li class="leaf"><a href="/research-areas/cellular-markers" title="">Cellular Markers</a></li> <li class="leaf"><a href="/research-areas/epigenetics" title="">Epigenetics</a></li> <li class="leaf"><a href="/research-areas/epitope-tags" title="">Epitope Tags</a></li> <li class="leaf"><a href="/research-areas/cell-biology/Exosome-research-tools" title="Exosome Research Tools">Exosomes Research</a></li> <li class="leaf"><a href="/research-areas/hypoxia" title="">Hypoxia</a></li> <li class="leaf"><a href="/research-areas/immunology" title="">Immunology</a></li> <li class="leaf"><a href="/research-areas/microbiology" title="">Microbiology</a></li> <li class="leaf"><a href="/research-areas/neuroscience" title="">Neuroscience</a></li> <li class="last leaf"><a href="/research-areas/stem-cells" title="">Stem Cells</a></li> </ul></li> </ul></li> <li class="last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/pathwaypages.html" title="">By Pathway</a><ul class="menu"><li class="first leaf"><a href="/akt-signaling-pathway" title="">AKT </a></li> <li class="leaf"><a href="/apoptosis-pathway" title="">Apoptosis</a></li> <li class="leaf"><a href="/autophagy-pathway" title="">Autophagy</a></li> <li class="leaf"><a href="/mapkerkpathway.html" title="">ERK1/2/5 Pathway</a></li> <li class="leaf"><a href="/hedgehogpathway.html" title="">Hedgehog</a></li> <li class="leaf"><a href="/hippo-pathway.html" title="">Hippo</a></li> <li class="leaf"><a href="/jnk-signaling-pathway" title="">JNK Pathway</a></li> <li class="leaf"><a href="/mtor-pathway" title="">mTOR</a></li> <li class="leaf"><a href="/necroptosis-pathway" title="">Necroptosis</a></li> <li class="leaf"><a href="/nfkbpathway" title="">NFKB Signaling</a></li> <li class="leaf"><a href="/p38mapkpathway.html" title="">p38 Signaling</a></li> <li class="leaf"><a href="/tgfbetapathway" title="">TGF Beta</a></li> <li class="last leaf"><a href="/toll-like-receptors" title="">TLR</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/research-areas.html" class="main_menu_parent_link">Research Areas</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_promotions" class="menu_drop"> <div class="mm_menu"><a href="/about/rewards.html"><div class="link_button">Get Rewards</div></a><ul class="menu"><li class="first last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/programs.html" title="">Customer Care</a><ul class="menu"><li class="first leaf"><a href="/guarantee" title="">100% Guarantee</a></li> <li class="leaf"><a href="/support/innovators-reward.html" title="">Risk Free Testing</a></li> <li class="leaf"><a href="/about/rewards.html" title="">Novus Rewards Program</a></li> <li class="leaf"><a href="/publications" title="">Publication Rewards Program</a></li> <li class="leaf"><a href="/newlab.html" title="">New Lab Discount</a></li> <li class="leaf"><a href="/scholarship-program.html" title="">Scholarship</a></li> <li class="leaf"><a href="/travelgrant.html" title="">Travel Grants</a></li> <li class="last leaf"><a href="/products/promotions" title="">Promotions</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/programs.html" class="main_menu_parent_link">Customer Care</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_about" class="menu_drop"> <div class="mm_menu"><a href="/about/careers-at-novus.html"><div class="link_button">Novus Careers</div></a><ul class="menu"><li class="first last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/about.html" title="">About us</a><ul class="menu"><li class="first leaf"><a href="https://www.bio-techne.com/about/careers" title="">Careers</a></li> <li class="leaf"><a href="/about/collaborations.html" title="">Collaborations</a></li> <li class="leaf"><a href="/about/events" title="Events">Events</a></li> <li class="leaf"><a href="/about/novus-story.html" title="">Novus Story</a></li> <li class="leaf"><a href="/about/novus-team.html" title="">Our Team</a></li> <li class="leaf"><a href="/about/novus-philanthropy.html" title="">Philanthropy</a></li> <li class="leaf"><a href="/about/press-release.html" title="">Press Releases</a></li> <li class="last leaf"><a href="/why-choose-novus.html" title="">Why choose Novus</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/about.html" class="main_menu_parent_link">About Us</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_contact" class="menu_drop"> <div class="mm_menu"><ul class="menu"><li class="first last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/about/contact-us.html" title="">Contact Us</a><ul class="menu"><li class="first leaf"><a href="/about/contact-us.html" title="">Customer Service</a></li> <li class="leaf"><a href="/novus-distributors/list" title="">Distributors</a></li> <li class="last leaf"><a href="/support/technical-support.html" title="">Technical Support</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/about/contact-us.html" class="main_menu_parent_link">Contact</a> </div> </li> </ul> </div> </div> </div> </div> </div> </div> </div> <div id="caspertesting"> <div class="container_16"> <div id="page-breadcrumb" class="grid_16"> <div class="breadcrumb"><a href="/">Home</a> &#187; <a href="/common-name/fgf-8">FGF-8</a> &#187; <a href="/proteins/fgf-8">FGF-8 Proteins</a> &#187; Recombinant Human/Mouse FGF-8b Protein</div> </div> <div class="main grid_16"> <!--&& !empty($title) to be added still--> <div class="region region-banners"> <div id="block-block-26" class="block block-block"> <div class="content"> <div class="container_12"><a href="https://www.bio-techne.com/account/novus-bio-techne/login?_ga=2.17257593.151271452&lt;br /&gt;&#10;5.1724696046-473375462.1712005244" style="margin: 0 10px;" target="_blank"><img alt="Novus Biologicals products are now on bio-techne.com" src="https://images.novusbio.com/design/ready-to-buy-novus-products-login.png" style="height:120px; width:940px" /></a></div> </div> </div> </div> <h1>Recombinant Human/Mouse FGF-8b Protein</h1> </div> <div class="clear"></div> <div> <div class="region region-content"> <div id="block-et-messages-et-messages-block" class="block block-et-messages"> <div class="content"> <span></span> </div> </div> <div id="block-system-main" class="block block-system"> <div class="content"> <div class="grid_16"><div class="ds_info float_left"><a href="#PublicationSection"><div class="sprite_pubBook_large"></div></a> <a href="#PublicationSection" class="bottom2"><span class="ctr">(62 Publications)</span></a></div><div class="ds_info float_left"><a href="#ReviewsSection"><div class="dsSprite_stars5"></div></a> <a href="#ReviewsSection" class="bottom0"><span class="ctr">(1 Review)</span></a></div><div class="ds_info float_left"> <a href="/common-name/fgf-8"><div class="sprite_allRelated"></div></a> <a href="/common-name/fgf-8" class="bottom4"><span class="ctr">See All Related</span></a> </div><div class="ds_info float_left"><a href="/reviews/423-F8"><div class="dsSprite_submitreview"></div></a> <a href="/reviews/423-F8" class="bottom4"><span class="ctr">Submit a Review</span></a></div></div></div><div class="modalWrapper" style="display:none;"> <h2>Species Glossary</h2> <hr class="customhr"/> <img src="//images.novusbio.com/design/bunny.gif" alt="Species Glossary Rabbit" style="float: right;"> <table class="modalTable"> <tr> <td>At</td> <td>=</td> <td>A. thaliana</td> <td>SyHa</td> <td>=</td> <td>Golden Syrian Hamster</td> </tr> <tr> <td>All</td> <td>=</td> <td>All Species</td> <td>Ha</td> <td>=</td> <td>Hamster</td> </tr> <tr> <td>An</td> <td>=</td> <td>Animal</td> <td>Hu</td> <td>=</td> <td>Human</td> </tr> <tr> <td>ArHa</td> <td>=</td> <td>Armenian Hamster</td> <td>I</td> <td>=</td> <td>Insect</td> </tr> <tr> <td>Av</td> <td>=</td> <td>Avian</td> <td>Ll</td> <td>=</td> <td>Llama</td> </tr> <tr> <td>Bb</td> <td>=</td> <td>Baboon</td> <td>Ma</td> <td>=</td> <td>Mammal</td> </tr> <tr> <td>Ba</td> <td>=</td> <td>Bacteria</td> <td>Mk</td> <td>=</td> <td>Monkey</td> </tr> <tr> <td>Bv</td> <td>=</td> <td>Bovine</td> <td>Mu</td> <td>=</td> <td>Mouse</td> </tr> <tr> <td>Ca</td> <td>=</td> <td>Canine</td> <td>Multi</td> <td>=</td> <td>Multi-species</td> </tr> <tr> <td>Ce</td> <td>=</td> <td>C. Elegans</td> <td>NA</td> <td>=</td> <td>Non-species specific</td> </tr> <tr> <td>Ch</td> <td>=</td> <td>Chicken</td> <td>Or</td> <td>=</td> <td>Orangutan</td> </tr> <tr> <td>ChHa</td> <td>=</td> <td>Chinese Hamster</td> <td>Pl</td> <td>=</td> <td>Plant</td> </tr> <tr> <td>Cm</td> <td>=</td> <td>Cynomolgus Monkey</td> <td>Pm</td> <td>=</td> <td>Primate</td> </tr> <tr> <td>Do</td> <td>=</td> <td>Donkey</td> <td>Po</td> <td>=</td> <td>Porcine</td> </tr> <tr> <td>Dr</td> <td>=</td> <td>Drosophilia</td> <td>Rb</td> <td>=</td> <td>Rabbit</td> </tr> <tr> <td>Ec</td> <td>=</td> <td>E. Coli</td> <td>Rt</td> <td>=</td> <td>Rat</td> </tr> <tr> <td>Eq</td> <td>=</td> <td>Equine</td> <td>RM</td> <td>=</td> <td>Rhesus Macaque</td> </tr> <tr> <td>Fe</td> <td>=</td> <td>Feline</td> <td>Sh</td> <td>=</td> <td>Sheep</td> </tr> <tr> <td>Ft</td> <td>=</td> <td>Ferret</td> <td>Vb</td> <td>=</td> <td>Vertebrate</td> </tr> <tr> <td>Fi</td> <td>=</td> <td>Fish</td> <td>Vi</td> <td>=</td> <td>Virus</td> </tr> <tr> <td>Fu</td> <td>=</td> <td>Fungi</td> <td>Xp</td> <td>=</td> <td>Xenopus</td> </tr> <tr> <td>Ge</td> <td>=</td> <td>Gerbil</td> <td>Ye</td> <td>=</td> <td>Yeast</td> </tr> <tr> <td>GP</td> <td>=</td> <td>Guinea Pig</td> <td>Ze</td> <td>=</td> <td>Zebrafish</td> </tr> <tr> <td>Gt</td> <td>=</td> <td>Goat</td> </tr> </table> <div style="text-align: center;margin-left:25px;margin-right:25px;"> <p>Note: Mouseover a species abbreviation on the product page to display the fullname.</p> </div> </div> </div><div class="clear"></div><div class="grid_10 pos_relative"><div class="ds_blue_border equaltop"><div class="imagesleft equaltop"><h2 class="blueHead">Images</h2> <div class="midBlue">&nbsp;</div><div class="images"><div id="ss_prev_top" class="cycle-pager"><div class="pager_left_on"></div></div><div class="cycle-slideshow slideshows" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-top" data-cycle-prev="#ss_prev_top" data-cycle-next="#ss_next_top" data-cycle-caption="#image-caption" data-cycle-caption-template="Image {{slideNum}} of {{slideCount}}" data-cycle-slides=".big_thumb_container" data-cycle-carousel-visible="4" id="images_cycle" > <div class="sub_image_wrapper"><div id="cycle-circle-pager-top" class="cycle-circle-pager"></div><div id="image-caption"></div> <a class="enlargeTop">(<div class="dsSprite_magGlass"></div> Enlarge)</a></div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize2/FGF8_423F8_1438.jpg" class="top_images" rel="gallery" title="Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin." > <img src="//images.novusbio.com/images2/FGF8_423F8_1438.jpg" class="big_thumb" alt="Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin." title="Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin." /> </a> </div> <div class="alt-caption padding_left5" >Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.</div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize2/FGF-8_423-F8_332.jpg" class="top_images" rel="gallery" title="1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa." > <img src="//images.novusbio.com/images2/FGF-8_423-F8_332.jpg" loading="lazy" style="display:none;" class="big_thumb" alt="1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa." title="1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa." /> </a> </div> <div class="alt-caption padding_left5" >1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.</div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/423-f8_recombinant-human-mouse-fgf-8b-protein-cell-culture-1052024145159..jpg" class="top_images" rel="gallery" title="Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively) to select and enrich for neural stem cell populations, and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Cells were stained with a Mouse Anti-Human/Mouse Tyrosine Hydroxylase Monoclonal Antibody (MAB7566) followed by a NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green), and a Mouse Neuron-specific beta III Tubulin Tuj1 Monoclonal Antibody (MAB1195) followed by a NorthernLights 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red) and counterstained with DAPI (5748; blue). " > <img src="//images.novusbio.com/images/423-f8_recombinant-human-mouse-fgf-8b-protein-cell-culture-1052024145159..jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively) to select and enrich for neural stem cell populations, and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Cells were stained with a Mouse Anti-Human/Mouse Tyrosine Hydroxylase Monoclonal Antibody (MAB7566) followed by a NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green), and a Mouse Neuron-specific beta III Tubulin Tuj1 Monoclonal Antibody (MAB1195) followed by a NorthernLights 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red) and counterstained with DAPI (5748; blue). " title="Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively) to select and enrich for neural stem cell populations, and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Cells were stained with a Mouse Anti-Human/Mouse Tyrosine Hydroxylase Monoclonal Antibody (MAB7566) followed by a NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green), and a Mouse Neuron-specific beta III Tubulin Tuj1 Monoclonal Antibody (MAB1195) followed by a NorthernLights 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red) and counterstained with DAPI (5748; blue). " /> </a> </div> <div class="alt-caption padding_left5" >Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013<a class="openGallery" href="#" data-picnum="2"> ...read more</a></div> </div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/423-f8_recombinant-human-mouse-fgf-8b-protein-cell-culture-1052024145958..jpg" class="top_images" rel="gallery" title="Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively), and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Tyrosine Hydroxylase was detected using a Mouse Anti-Human Tyrosine Hydroxylase Monoclonal Antibody (MAB7566). The cells were stained with the NorthernLights&#8482; 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red). Neuron-specific beta-III Tubulin was detected using a Mouse Anti-Neuron-specific beta-III Tubulin (Clone Tuj-1) Monoclonal Antibody (MAB1195) followed by the NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green). Cells were counterstained with DAPI (5748; blue). " > <img src="//images.novusbio.com/images/423-f8_recombinant-human-mouse-fgf-8b-protein-cell-culture-1052024145958..jpg" loading="lazy" style="display:none;" class="big_thumb" alt="Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively), and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Tyrosine Hydroxylase was detected using a Mouse Anti-Human Tyrosine Hydroxylase Monoclonal Antibody (MAB7566). The cells were stained with the NorthernLights&#8482; 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red). Neuron-specific beta-III Tubulin was detected using a Mouse Anti-Neuron-specific beta-III Tubulin (Clone Tuj-1) Monoclonal Antibody (MAB1195) followed by the NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green). Cells were counterstained with DAPI (5748; blue). " title="Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013 and AR003, respectively), and a panel of growth factors for effective dopaminergic differentiation, including Recombinant Human FGF-basic, Recombinant Mouse FGF-8b (Catalog # 423-F8), and Recombinant Mouse Shh-N (464-SH). Tyrosine Hydroxylase was detected using a Mouse Anti-Human Tyrosine Hydroxylase Monoclonal Antibody (MAB7566). The cells were stained with the NorthernLights&#8482; 557-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL007; red). Neuron-specific beta-III Tubulin was detected using a Mouse Anti-Neuron-specific beta-III Tubulin (Clone Tuj-1) Monoclonal Antibody (MAB1195) followed by the NorthernLights&#8482; 493-conjugated Donkey Anti-Mouse IgG Antigen Affinity-purified Secondary Antibody (NL009; green). Cells were counterstained with DAPI (5748; blue). " /> </a> </div> <div class="alt-caption padding_left5" >Dopaminergic neurons were generated from human pluripotent stem cells in media that included Bovine Fibronectin Protein (1030-FN) to support cell attachment and spreading, the ITS and N-2 Plus Media Supplements (AR013<a class="openGallery" href="#" data-picnum="3"> ...read more</a></div> </div></div><div id="ss_next_top" class="cycle-pager"><div class="pager_right_on"></div></div></div></div><div class="productsright pos_relative equaltop"><h2 class="blueHead">Product Details</h2> <div class="midBlue">Summary</div><table class="ds_list"><tr class="lined"> <td><strong>Reactivity</strong></td> <td><span title='Human'>Hu</span>, <span title='Mouse'>Mu</span><span class="myModal">Species Glossary</span></td> </tr><tr class="lined"> <td><strong>Applications</strong></td> <td><span title='Bioactivity'>Bioactivity</span></td> </tr></table></div> </div></div><div class="grid_6"><div></div> <div class="ds_blue_border equaltop"> <h2 class="blueHead_nopadding">Order Details</h2><ul class="ds_details"><li class="add-to-cart" data-type="full" data-prodname="Recombinant Human/Mouse FGF-8b Protein" data-catnum="423-F8" data-catnums="423-F8-025,423-F8-01M" data-disabled=''><noscript><form autocomplete="off" action="/products/recombinant-human-mouse-fgf-8b-protein_423-f8" method="post" id="et-add-multiple-to-cart-form" accept-charset="UTF-8"><div><table class="sticky-enabled"> <thead><tr><th>Size</th><th>Price</th> </tr></thead> <tbody> <tr class="odd"><td><div class="atc_size" title="catalog # 423-F8-025">25 ug</div><div data-msg='' class="atc_catnum">423-F8-025</div></td><td><div style="font-size:11px;"><a class="jump_distributor" href="#jump_distributor">Contact Your<br />Distributor</a></div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">4-6 Business Days</td> </tr> <tr class="odd"><td><div class="atc_size" title="catalog # 423-F8-01M">1 mg</div><div data-msg='' class="atc_catnum">423-F8-01M</div></td><td><div style="font-size:11px;"><a class="jump_distributor" href="#jump_distributor">Contact Your<br />Distributor</a></div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">4-6 Business Days</td> </tr> </tbody> </table> <input type="hidden" name="form_build_id" value="form-g84-VThO0ZqcLZpgH_of53bmKTqKvrZrwGdtnD-Xs48" /> <input type="hidden" name="form_id" value="et_add_multiple_to_cart_form" /> </div></form></noscript></li></ul><div id="shipping" class="hidden"></td></tr></div><div class="conj_form_buttons"><div class="list_expand options_closed" data-name="Formulations" data-wrapper-type=".formulations_wrapper"><div class="options_text">View Available Formulations</div> <div class="expander option_closed"></div></div><div class="formulations_wrapper" data-title="Recombinant Human/Mouse FGF-8b Protein" data-catnum="423-F8"><table class="scf_table"> <thead> <tr> <th>Catalog# &amp; Formulation</th> <th>Size</th> <th class="col_price">Price</th> <th class="col_cart"></th> </tr> </thead> <tbody><tr class="popup_sku" data-sku="423-F8-025/CF"> <td> <a href="/products/recombinant-human-mouse-fgf-8b-protein-cf_423-f8-cf" class="conj_link">Carrier Free</a><br /> <a href="/products/recombinant-human-mouse-fgf-8b-protein-cf_423-f8-cf" class="cat_link">423-F8-025/CF</a> </td> <td><div class="popup_size"></div></td> <td class="col_price"><div class="popup_price"></div></td> <td class="col_cart"><a href="/commerce/add-to-cart/446681"><div class="purchase_cart"></div></a></td> </tr> <tr> <td colspan="4" class="row_stock"><div class="popup_stock"></div></td> </tr> <tr class="scf_footer"> <td colspan="4"><div class="expander option_opened"></div></td> </tr> </tbody> </table> <div class="popup_skus" data-skus='["423-F8-025\/CF"]' data-rendered="false"></div></div></div><div id="shipping_statement"><span id="shipping_rate"></span></div><div class="shipping_obt_transfer"><span>Novus Biologicals is part of Bio-Techne</span><br><br><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-mouse-fgf-8b-protein_423-f8" rel="follow" class="btn btn-primary">Shop this product on bio-techne.com</a></div><br><div class="learn_more"> <a href="/guarantee"> <div class="sprite_noImage" title="Novus Biologicals, part of Bio-Techne, offers 100% Guarantee"></div> <div class="learn_more_text">Novus Biologicals, part of Bio-Techne, offers 100% Guarantee</div></a> </div><span id="conj_form" class="hidden"><tr><td colspan="4"></td></tr></span> </div> </div><div class="clear"></div><div class="grid_10"><div><div id="ds_tabs" style="display:none;"> <div class="ds_tab_active" id="dsTabs_datasheet" data-anchor_desc="datasheet">Datasheet</div> <div class="ds_tab" id="dsTabs_reviews-publications" data-anchor_desc="reviews-publications">Reviews &amp; Publications</div> <div class="ds_tab" id="dsTabs_protocols-faqs" data-anchor_desc="protocols-faqs">Protocols &amp; FAQs</div> <div class="ds_tab" id="dsTabs_supportresearch" data-anchor_desc="supportresearch">Support &amp; Research</div> </div><div class="ds_tab_content equalbottom" id="content_datasheet" > <a id="datasheet"></a><h2 class=greyHead2>Recombinant Human/Mouse FGF-8b Protein Summary</h2> <div class="ds_info"> <a id="tab1details"></a> <table class="ds_list wide" style="table-layout:fixed;"> <tr class="lined"> <td><strong>Details of Functionality</strong></td> <td><div>Measured in a cell proliferation assay using NR6R&#x2011;3T3 mouse fibroblast cells. Raines, E.W. <EM>et al</EM>. (1985) Methods Enzymol. <STRONG>109</STRONG>:749. The ED<sub>50</sub> for this effect is typically&nbsp;6.5-40 ng/mL in the presence of 1 µg/mL heparin.</div></td> </tr><tr class="lined"> <td><strong>Source</strong></td> <td><div><EM>E. coli</EM>-derived FGF-8 protein<br />Gln23-Arg215, with an N-terminal Met</div></td> </tr><tr class="lined"> <td><strong>Accession #</strong></td> <td><div><a href="http://www.ncbi.nlm.nih.gov/protein/NP_006110 (human), NP_001159834 (mouse)" target="_blank" >NP_006110 (human), NP_001159834 (mouse)</a></div></td> </tr><tr class="lined"> <td><strong>N-terminal Sequence</strong></td> <td><div>Met</div></td> </tr><tr class="lined"> <td><strong> Protein/Peptide Type</strong></td> <td><div>Recombinant Proteins</div></td> </tr><tr class="lined"> <td><strong>Gene</strong></td> <td><div>FGF8</div></td> </tr><tr class="lined"> <td><strong>Purity</strong></td> <td><div>>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.</div></td> </tr><tr class="lined"> <td><strong>Endotoxin Note</strong></td> <td><div><0.01 EU per 1 μg of the protein by the LAL method.</div></td> </tr> </table> </div> <h2 class="greyHead2">Applications/Dilutions</h2> <div class="ds_info"> <a id="tab1appsdiluts"></a> <table class="ds_list wide"> <tr class="lined"> <td><strong>Dilutions</strong></td> <td> <ul class="ds_noDotList"><li>Bioactivity </li> </ul> </td> </tr><tr class="lined"> <td><strong>Theoretical MW</strong></td> <td><div>22.5 kDa.<br> Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.</div></td> </tr><tr class="lined"> <td><strong>SDS-PAGE</strong></td> <td><div>23 kDa, reducing conditions</div></td> </tr><tr class="lined"> <td><strong>Reviewed Applications</strong></td> <td> <table class="wide"> <tr> <td> Read <a href="#ReviewsSection">1 Review</a> rated 5<div class="dsSprite_stars5"></div> using <br/>423-F8 in the following application:<br /><br /> <ul class="information-list"><li> <div class="information-subject"><a href="#ReviewsSection" class="filter_link" data-destination="review" data-type="application" data-filter="Stem/Immune cell maintenance or differentiation ">Stem/Immune cell maintenance or differentiation </a></div> <div class="information-data"></div> </li> </ul> </td> </tr> </table> </td> </tr><tr class="lined"> <td><strong>Publications</strong></td> <td> <table> <tr> <td>Read <a href="#PublicationSection"> Publications</a> using<br/> 423-F8 in the following applications:<br /><br /> <ul class="information-list"><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Bioassay">Bioassay</a> </div><div class="information-data">45 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Cell Culture">Cell Culture</a> </div><div class="information-data">6 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="Differentiation">Differentiation</a> </div><div class="information-data">4 publications</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="In Ovo">In Ovo</a> </div><div class="information-data">1 publication</div></li><li class="noIndent"><div class="information-subject"> <a href="#PublicationSection" class="filter_link" data-destination="publication" data-type="application" data-filter="In Vivo">In Vivo</a> </div><div class="information-data">8 publications</div></li></ul></td> </tr> </table> </td> </tr> </table> </div> <h2 class="greyHead2">Packaging, Storage & Formulations</h2><div class="ds_info"><table class="ds_list"><tr class="lined"> <td><strong>Storage</strong></td> <td><div><b>Use a manual defrost freezer and avoid repeated freeze-thaw cycles.</b><UL><LI>12 months from date of receipt, -20 to -70 °C as supplied.</LI><LI>3 months, 2 to 8 °C under sterile conditions after reconstitution.</LI></UL></div></td> </tr><tr class="lined"> <td><strong>Buffer</strong></td> <td><div>Lyophilized from a 0.2 μm filtered solution in MOPS, Na<SUB>2</SUB>SO<SUB>4</SUB> and Brij-35 with BSA as a carrier protein.</div></td> </tr><tr class="lined"> <td><strong>Purity</strong></td> <td><div>>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.</div></td> </tr><tr class="lined"> <td><strong>Reconstitution Instructions</strong></td> <td><div>Reconstitute at 25 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.</div></td> </tr></table></div> <h2 class="greyHead2">Notes</h2><div class="ds_info"> <a id="tab1notes"></a> <div>This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.</div> </div><h2 class="greyHead2">Alternate Names for Recombinant Human/Mouse FGF-8b Protein</h2> <div class="ds_info"> <a id="tab1altnames"></a> <div class="information-list"> <ul><li>AIGF</li><li>AIGFKAL6</li><li>Androgen-induced growth factor</li><li>FGF8</li><li>FGF-8</li><li>fibroblast growth factor 8 (androgen-induced)</li><li>fibroblast growth factor 8</li><li>HBGF-8</li><li>Heparin-binding growth factor 8</li><li>MGC149376</li></ul></div> </div> <h2 class="greyHead2">Background</h2> <div class="ds_info"> <a id="tab1background"></a> <div><P>FGF-8 is a member of the fibroblast growth factor family that was originally discovered as a growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells (1-3). Alternate splicing of mouse FGF-8 mRNA generates eight secreted isoforms, designated a-h, but only FGF-8a, b, e and f exist in humans (4). FGF-8 contains a 22 amino acid (aa) signal sequence, an N‑terminal domain that varies according to the isoform (30 aa for FGF-8b; 20 aa for the shortest, FGF-8a), a 125&nbsp;aa FGF domain and a 37 aa proline‑rich C‑terminal sequence. The FGF domain of FGF-8 shares the most aa identity with FGF17 (75%)&nbsp;and FGF-18 (67%), and the three form an FGF subfamily (2). Mouse FGF-8b shares 100% aa identity with human FGF-8b<EM>.</EM> FGF-8 is widely expressed during embryogenesis, and mediates epithelial-mesenchymal transitions. It plays an organizing and inducing role during gastrulation, and regulates patterning of the midbrain/hindbrain, eye, ear, limbs and heart in the embryo (2,&nbsp;5&nbsp;-&nbsp;8). The isoforms may play different roles in development. FGF-8b shows the strongest receptor affinity and oncogenic transforming capacity although FGF-8a and&nbsp;FGF-8e are also transforming and have been found in human prostate, breast or ovarian tumors (1,&nbsp;5,&nbsp;9-12). FGF-8 shows limited expression in the normal adult, but low levels are found in the reproductive and genitourinary tract, peripheral leukocytes and bone marrow hematopoietic cells (3,&nbsp;9,&nbsp;13).</P><div class="backref"><OL> <LI>Mattila, M.M.&nbsp;and P.L. Harkonen (2007) Cytokine Growth Factor Rev. <STRONG>18</STRONG>:257.</LI> <LI>Reuss, B.&nbsp;and O. von Bohlen und Halbach (2003) Cell Tiss. Res. <STRONG>313</STRONG>:139.</LI> <LI>Tanaka, A. <EM>et al.</EM> (1992) Proc. Natl. Acad. Sci. USA <STRONG>89</STRONG>:8928.</LI> <LI>Gemel, J. <EM>et al.</EM> (1996) Genomics <STRONG>35</STRONG>:253.</LI> <LI>Olsen, S.K. <EM>et al.</EM> (2006) Genes Dev. <STRONG>20</STRONG>:185.</LI> <LI>Crossley, P.H. <EM>et al</EM>. (1996) Cell, <STRONG>84</STRONG>:127.</LI> <LI>Heikinheimo, M. <EM>et al.</EM> (1994) Mech. Dev. <STRONG>48</STRONG>:129.</LI> <LI>Sun, X. <EM>et al.</EM> (1999) Genes Dev. <STRONG>13</STRONG>:1834. </LI> <LI>Ghosh, A.K. <EM>et al</EM>. (1996) Cell Growth Differ. <STRONG>7</STRONG>:1425.</LI> <LI>Mattila, M.M. <EM>et al.</EM> (2001) Oncogene <STRONG>20</STRONG>:2791.</LI> <LI>Valve, E. <EM>et al.</EM> (2000) Int. J. Cancer <STRONG>88</STRONG>:718.</LI> <LI>Valve, E.M. <EM>et al.</EM> (2001) Lab. Invest. <STRONG>81</STRONG>:815.</LI> <LI>Nezu, M. <EM>et al.</EM> (2005) Biochem. Biophys. Res. Commun. <STRONG>335</STRONG>:843.</LI></OL></div></div> </div><h2 class="greyHead2">Customers Who Viewed This Item Also Viewed...</h2> <a id="custalsoviewed"></a><div id="cav_prev"><div class="sprite_leftArrow"></div></div> <div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout=0 data-cycle-prev="#cav_prev" data-cycle-next="#cav_next" data-cycle-slides="div.ds_cav_group" id="ds_customer_also_viewed"><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="464-SH"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-mouse-sonic-hedgehog-shh-c25ii-n-terminus_464-sh" style="overflow: hidden; width: 280px;" title="Sonic Hedgehog/Shh [Unconjugated]">Sonic Hedgehog/Shh<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="464-SH" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="464-SH" data-baseurl="https://www.novusbio.com" data-productid="445073"></div>--> <!-- <a href="/commerce/add-to-cart/445073"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">464-SH</div> <div class="images_customers"><div id="ss_prev_cav0" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-0" data-cycle-prev="#ss_prev_cav0" data-cycle-next="#ss_next_cav0" data-cycle-slides="div.big_thumb_cust_container" data-index=0 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-mouse-sonic-hedgehog-shh-c25ii-n-terminus_464-sh" title="Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus (Catalog # 464-SH) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The activity is more than 30-fold greater than the top competitor's Sonic Hedgehog." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images2/Sonic_Hedgehog_464SH_2840.jpg" alt="Bioactivity Sonic Hedgehog/Shh [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-mouse-sonic-hedgehog-shh-c25ii-n-terminus_464-sh" title="1&amp;amp;nbsp;μg/lane of Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 22 kDa." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images2/Sonic_Hedgehog_464-SH_341.jpg" alt="SDS-PAGE Sonic Hedgehog/Shh [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-mouse-sonic-hedgehog-shh-c25ii-n-terminus_464-sh" title="Recombinant Mouse Sonic Hedgehog/Shh (C25II), N-Terminus (Catalog # 464-SH) has a molecular weight (MW) of 20.7 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation)." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/464-sh_recombinant-mouse-sonic-hedgehog-shh-c25ii-n-terminus-sec-mals-642023224324.jpg" alt="SEC-MALS Sonic Hedgehog/Shh [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav0" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-0" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-mouse-sonic-hedgehog-shh-c25ii-n-terminus_464-sh#PublicationSection"> <div class="sprite_pubBook"></div> (69 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Mu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="314-BP"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-bmp-4-protein_314-bp" style="overflow: hidden; width: 280px;" title="BMP-4 [Unconjugated]">BMP-4<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="314-BP" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="314-BP" data-baseurl="https://www.novusbio.com" data-productid="447418"></div>--> <!-- <a href="/commerce/add-to-cart/447418"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">314-BP</div> <div class="images_customers"><div id="ss_prev_cav1" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-1" data-cycle-prev="#ss_prev_cav1" data-cycle-next="#ss_next_cav1" data-cycle-slides="div.big_thumb_cust_container" data-index=1 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-bmp-4-protein_314-bp" title="1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.&amp;amp;nbsp;" class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images2/BMP-4_314-BP_100.jpg" alt="SDS-PAGE BMP-4 [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-bmp-4-protein_314-bp" title="Recombinant Human BMP‑4 (Catalog # 314-BP) induces BMP responsive SEAP reporter activity in HEK293 human embryonic kidney cells. The ED50 for this effect is 0.70-7.00 ng/mL." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images2/314-bp_recombinant-human-bmp-4-protein-1882021123744.jpg" alt="Bioactivity BMP-4 [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav1" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-1" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-bmp-4-protein_314-bp#PublicationSection"> <div class="sprite_pubBook"></div> (519 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA, BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="235-F4"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-fgf-4-protein_235-f4" style="overflow: hidden; width: 280px;" title="FGF-4 [Unconjugated]">FGF-4<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="235-F4" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="235-F4" data-baseurl="https://www.novusbio.com" data-productid="447464"></div>--> <!-- <a href="/commerce/add-to-cart/447464"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">235-F4</div> <div class="images_customers"><div id="ss_prev_cav2" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-2" data-cycle-prev="#ss_prev_cav2" data-cycle-next="#ss_next_cav2" data-cycle-slides="div.big_thumb_cust_container" data-index=2 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-4-protein_235-f4" title="1 μg/lane of Recombinant Human FGF-4 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 16 kDa." class="cust_viewed_2" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF-4_235-F4_472.jpg" alt="SDS-PAGE FGF-4 [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-4-protein_235-f4" title="Recombinant Human FGF-4 (Catalog # 235&amp;amp;#8209;F4) stimulates cell proliferation of the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 0.25&amp;amp;#8209;1.25&amp;amp;nbsp;ng/mL." class="cust_viewed_2" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF-4_235-F4_483.jpg" alt="Bioactivity FGF-4 [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav2" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-2" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-fgf-4-protein_235-f4#PublicationSection"> <div class="sprite_pubBook"></div> (75 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="233-FB"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb" style="overflow: hidden; width: 280px;" title="FGF basic/FGF2/bFGF [Unconjugated]">FGF<br> basic/FGF2/bFGF [Unco</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="233-FB" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="233-FB" data-baseurl="https://www.novusbio.com" data-productid="447504"></div>--> <!-- <a href="/commerce/add-to-cart/447504"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">233-FB</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-3" data-cycle-prev="#ss_prev_cav3" data-cycle-next="#ss_next_cav3" data-cycle-slides="div.big_thumb_cust_container" data-index=3 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb" title="FGF basic/FGF2/bFGF [Unconjugated]" class="cust_viewed_3"> <img loading="lazy" src="/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png" alt="FGF basic/FGF2/bFGF [Unconjugated]" title="FGF basic/FGF2/bFGF [Unconjugated]" class=" big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb#PublicationSection"> <div class="sprite_pubBook"></div> (548 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="345-FG"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-fgf-10-protein_345-fg" style="overflow: hidden; width: 280px;" title="FGF-10 [Unconjugated]">FGF-10<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="345-FG" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="345-FG" data-baseurl="https://www.novusbio.com" data-productid="446959"></div>--> <!-- <a href="/commerce/add-to-cart/446959"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">345-FG</div> <div class="images_customers"><div id="ss_prev_cav4" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-4" data-cycle-prev="#ss_prev_cav4" data-cycle-next="#ss_next_cav4" data-cycle-slides="div.big_thumb_cust_container" data-index=4 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-10-protein_345-fg" title="1&amp;amp;nbsp;μg/lane of Recombinant Human FGF-10 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at&amp;amp;nbsp;21&amp;amp;nbsp;kDa." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF-10_345-FG_557.jpg" alt="SDS-PAGE FGF-10 [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-10-protein_345-fg" title="Recombinant Human FGF-10 (Catalog # 345-FG) stimulates cell proliferation of the 4MBr‑5 rhesus monkey epithelial cell line. The ED50 for this effect is 20&amp;amp;#8209;100&amp;amp;nbsp;ng/mL. " class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF-10_345-FG_559.jpg" alt="Bioactivity FGF-10 [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-10-protein_345-fg" title="Adult stem cells isolated from human lung biopsy tissue were embedded in Cultrex UltiMatrix RGF Basement Membrane Extract (BME001-05) and cultured for 20-60 days in lung organoid expansion medium, which includes Recombinant Human FGF-10 (Catalog # 345-FG), Recombinant Human KGF/FGF-7 (251-KG), Recombinant Human Noggin (6057-NG), and Recombinant Human R-Spondin 1 (4645-RS), along with the other reagents listed in the lung organoid expansion medium recipe in the lung organoid culture protocol. Lung organoids were able to differentiate and exhibit markers for various cell types of the lung. Lung organoids were stained with (A) a Rabbit Anti-Human Cytokeratin 5 (KRT5) Monoclonal Antibody (Novus Biologicals, Catalog # NB110-56916; green) and a Goat Anti-Human p63/TP73L Polyclonal Antibody (AF1916; red) to visualize basal cells, (B) a Hamster Anti-Mouse Podoplanin (PDPN) Monoclonal Antibody (Novus Biologicals, Catalog # NB600-1015; green) to visualize alveolar type I cells and a Goat Anti-Human p63/TP73L Polyclonal Antibody (AF1916; red) to visualize basal cells, and (C, D) a Mouse Anti-MUC5AC Monoclonal Antibody (Novus Biologicals, Catalog # NBP2-15196; green) to visualize Goblet cells and a Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (MAB2018; red). All samples were counterstained with DAPI (5748; blue). " class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images/345-fg_recombinant-human-fgf-10-protein-bioactivity-2520239220..jpg" alt="Bioactivity FGF-10 [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav4" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-4" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-fgf-10-protein_345-fg#PublicationSection"> <div class="sprite_pubBook"></div> (103 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB600-1287"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/fgfr1-antibody-m19b2_nb600-1287" style="overflow: hidden; width: 280px;" title="FGFR1 Antibody (M19B2) - BSA Free">FGFR1 Antibody<br> (M19B2) - BSA Free</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="NB600-1287" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="NB600-1287" data-baseurl="https://www.novusbio.com" data-productid="78341"></div>--> <!-- <a href="/commerce/add-to-cart/78341"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">NB600-1287</div> <div class="images_customers"><div id="ss_prev_cav5" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-5" data-cycle-prev="#ss_prev_cav5" data-cycle-next="#ss_next_cav5" data-cycle-slides="div.big_thumb_cust_container" data-index=5 ><div class="big_thumb_cust_container"> <a href="/products/fgfr1-antibody-m19b2_nb600-1287" title="Flow Cytometry: FGF R1 Antibody (M19B2) [NB600-1287] - Analysis using the Alexa Fluor 488 (R) conjugate of NB600-1287. Staining of FGF R1 in HEK293 and HEK293 FGFR transfected cells using anti-FGF R1 antibody. (Red) Positive cells, (Green) Negative cells, (Blue) Negative cells + antibody, (Pink) Positive cells + antibody. Image from verified customer review." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/FGF-R1-Antibody-M19B2-Flow-Cytometry-NB600-1287-img0009.jpg" alt="Flow Cytometry FGFR1 Antibody (M19B2) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/fgfr1-antibody-m19b2_nb600-1287" title="Flow Cytometry: FGF R1 Antibody (M19B2) [NB600-1287] - Intracellular flow cytometric staining of 1 x 10^6 HEK-293 cells using FGF R1 antibody (Dark Blue) and Isotype control (Orange). An antibody concentration of 1 ug/1x10^6 cells was used." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/FGF-R1-Antibody-M19B2-Flow-Cytometry-NB600-1287-img0005.jpg" alt="Flow Cytometry FGFR1 Antibody (M19B2) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/fgfr1-antibody-m19b2_nb600-1287" title="Western Blot: FGF R1 Antibody (M19B2) [NB600-1287] - Analysis of MCF7 (A), HepG2 (B), NIH3T3 (C), and PC-12 (D) cell lysate using FGF R1 antibody at 2 ug/ml." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/FGF-R1-Antibody-M19B2-Western-Blot-NB600-1287-img0007.jpg" alt="Western Blot FGFR1 Antibody (M19B2) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav5" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-5" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/fgfr1-antibody-m19b2_nb600-1287#ReviewsSection"> <div class="sprite_5Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/fgfr1-antibody-m19b2_nb600-1287#PublicationSection"> <div class="sprite_pubBook"></div> (7 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Ca, Hu, Mu, Rb, Rt</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, Flow, ICC/IF, IHC, IHC-P, IP, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="H00002263-M01"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/fgfr2-antibody-1g3_h00002263-m01" style="overflow: hidden; width: 280px;" title="FGFR2 Antibody (1G3)">FGFR2 Antibody<br> (1G3)</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="H00002263-M01" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="H00002263-M01" data-baseurl="https://www.novusbio.com" data-productid="84633"></div>--> <!-- <a href="/commerce/add-to-cart/84633"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">H00002263-M01</div> <div class="images_customers"><div id="ss_prev_cav6" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-6" data-cycle-prev="#ss_prev_cav6" data-cycle-next="#ss_next_cav6" data-cycle-slides="div.big_thumb_cust_container" data-index=6 ><div class="big_thumb_cust_container"> <a href="/products/fgfr2-antibody-1g3_h00002263-m01" title="Immunohistochemistry-Paraffin: FGFR2 Antibody (1G3) [H00002263-M01] - Analysis of monoclonal antibody to FGFR2 on formalin-fixed paraffin-embedded human stomach carcinoma tissue. Antibody concentration 5 ug/ml." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images/FGFR2-Antibody-1G3-Immunohistochemistry-Paraffin-H00002263-M01-img0006.jpg" alt="Immunohistochemistry-Paraffin FGFR2 Antibody (1G3)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/fgfr2-antibody-1g3_h00002263-m01" title="Western Blot: FGFR2 Antibody (1G3) [H00002263-M01] - Analysis of FGFR2 expression in transfected 293T cell line by FGFR2 monoclonal antibody (M01), clone 1G3.Lane 1: FGFR2 transfected lysate (Predicted MW: 92 KDa).Lane 2: Non-transfected lysate." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images/FGFR2-Antibody-1G3-Western-Blot-H00002263-M01-img0008.jpg" alt="Western Blot FGFR2 Antibody (1G3)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/fgfr2-antibody-1g3_h00002263-m01" title="Sandwich ELISA: FGFR2 Antibody (1G3) [H00002263-M01] - Detection limit for recombinant GST tagged FGFR2 is approximately 0.03ng/ml as a capture antibody." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images/FGFR2-Antibody-1G3-Sandwich-ELISA-H00002263-M01-img0007.jpg" alt="Sandwich ELISA FGFR2 Antibody (1G3)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav6" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-6" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/fgfr2-antibody-1g3_h00002263-m01#PublicationSection"> <div class="sprite_pubBook"></div> (13 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Bv, Hu</div><div class="tiny"><strong>Applications:</strong> ELISA, ICC/IF, IHC, IHC-P, S-ELISA, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="1206-F3"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-fgf-3-protein_1206-f3" style="overflow: hidden; width: 280px;" title="FGF-3 [Unconjugated]">FGF-3<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="1206-F3" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="1206-F3" data-baseurl="https://www.novusbio.com" data-productid="447850"></div>--> <!-- <a href="/commerce/add-to-cart/447850"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">1206-F3</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-7" data-cycle-prev="#ss_prev_cav7" data-cycle-next="#ss_next_cav7" data-cycle-slides="div.big_thumb_cust_container" data-index=7 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-fgf-3-protein_1206-f3" title="FGF-3 [Unconjugated]" class="cust_viewed_7"> <img loading="lazy" src="/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png" alt="FGF-3 [Unconjugated]" title="FGF-3 [Unconjugated]" class=" big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-fgf-3-protein_1206-f3#PublicationSection"> <div class="sprite_pubBook"></div> (14 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF1979"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/otx2-antibody_af1979" style="overflow: hidden; width: 280px;" title="Otx2 Antibody [Unconjugated]">Otx2 Antibody<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="AF1979" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="AF1979" data-baseurl="https://www.novusbio.com" data-productid="413358"></div>--> <!-- <a href="/commerce/add-to-cart/413358"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">AF1979</div> <div class="images_customers"><div id="ss_prev_cav8" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-8" data-cycle-prev="#ss_prev_cav8" data-cycle-next="#ss_next_cav8" data-cycle-slides="div.big_thumb_cust_container" data-index=8 ><div class="big_thumb_cust_container"> <a href="/products/otx2-antibody_af1979" title="Otx2 was detected in immersion fixed NTera-2 human testicular embryonic carcinoma cell line using Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1979) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights&amp;amp;#8482; 557-conjugated Anti-Goat IgG Secondary Antibody (yellow, upper panel; Catalog # NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/Otx2_AF1979_Immunocytochemistry_11033.jpg" alt="Immunocytochemistry Otx2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/otx2-antibody_af1979" title=" Otx2 was detected in immersion fixed paraffin-embedded sections of mouse embryo (14 d.p.c.) using Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1979) at 1&amp;amp;nbsp;µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte&amp;amp;#8482; HRP Polymer Antibody (Catalog&amp;amp;nbsp;# VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to developing nervous system. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents. " class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/Otx2_AF1979_Immunohistochemistry_22974.jpg" alt="Immunohistochemistry Otx2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/otx2-antibody_af1979" title=" Simple Western lane view shows lysates of IMR‑32 human neuroblastoma cell line, loaded at 0.2&amp;amp;nbsp;mg/mL. A specific band was detected for Otx2 at approximately 48&amp;amp;nbsp;kDa (as indicated) using 10&amp;amp;nbsp;µg/mL of Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1979) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog&amp;amp;nbsp;# HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. " class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images2/Otx2_AF1979_Simple_Western_20223.jpg" alt="Simple Western Otx2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav8" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-8" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/otx2-antibody_af1979#ReviewsSection"> <div class="sprite_5Stars"></div> (2 Reviews</a>) </div> <div class="tiny"> <a href="/products/otx2-antibody_af1979#PublicationSection"> <div class="sprite_pubBook"></div> (175 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC, IHC, Simple Western, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF3364"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/pax2-antibody_af3364" style="overflow: hidden; width: 280px;" title="Pax2 Antibody [Unconjugated]">Pax2 Antibody<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="AF3364" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="AF3364" data-baseurl="https://www.novusbio.com" data-productid="413562"></div>--> <!-- <a href="/commerce/add-to-cart/413562"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">AF3364</div> <div class="images_customers"><div id="ss_prev_cav9" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-9" data-cycle-prev="#ss_prev_cav9" data-cycle-next="#ss_next_cav9" data-cycle-slides="div.big_thumb_cust_container" data-index=9 ><div class="big_thumb_cust_container"> <a href="/products/pax2-antibody_af3364" title="Pax2 was detected in immersion fixed BG01V human embryonic stem cells differentiated into the early otic lineage using Goat Anti-Human Pax2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3364) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights&amp;amp;#8482; 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images2/Pax2_AF3364_Immunocytochemistry_14405.jpg" alt="Immunocytochemistry Pax2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/pax2-antibody_af3364" title="Western blot shows lysates of mouse fetal kidney. PVDF Membrane was probed with 1&amp;amp;nbsp;µg/mL of Goat Anti-Human Pax2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3364) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for Pax2 at approximately 47&amp;amp;nbsp;kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images2/af3364_human-pax2-affinity-purified-polyclonal-ab-western-blot-145202183852.jpg" alt="Western Blot Pax2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/pax2-antibody_af3364" title="Pax2 was detected in immersion fixed paraffin-embedded sections of human kidney using Goat Anti-Human Pax2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3364) at 1&amp;amp;#160;&amp;amp;micro;g/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte&amp;amp;trade; HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei in convoluted tubules. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images2/af3364_human-pax2-affinity-purified-polyclonal-ab-immunohistochemistry-192021142455.jpg" alt="Immunohistochemistry Pax2 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav9" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-9" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/pax2-antibody_af3364#PublicationSection"> <div class="sprite_pubBook"></div> (28 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC, IHC, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="355-BM"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-mouse-rat-bmp-2-protein_355-bm" style="overflow: hidden; width: 280px;" title="BMP-2 [Unconjugated]">BMP-2<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="355-BM" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="355-BM" data-baseurl="https://www.novusbio.com" data-productid="446807"></div>--> <!-- <a href="/commerce/add-to-cart/446807"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">355-BM</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-10" data-cycle-prev="#ss_prev_cav10" data-cycle-next="#ss_next_cav10" data-cycle-slides="div.big_thumb_cust_container" data-index=10 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-mouse-rat-bmp-2-protein_355-bm" title="Recombinant human/mouse/rat BMP-2 (355-BM) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for this effect is 40-200 ng/mL." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/protein/355-bm_recombinant-human-mouse-rat-bmp-2-protein-bioactivity-181120209742.jpg" alt="Bioactivity BMP-2 [Unconjugated]" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-mouse-rat-bmp-2-protein_355-bm#PublicationSection"> <div class="sprite_pubBook"></div> (190 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP1-51575"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/wnt-1-antibody-10c8_nbp1-51575" style="overflow: hidden; width: 280px;" title="Wnt-1 Antibody (10C8) - BSA Free">Wnt-1 Antibody<br> (10C8) - BSA Free</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="NBP1-51575" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="NBP1-51575" data-baseurl="https://www.novusbio.com" data-productid="221662"></div>--> <!-- <a href="/commerce/add-to-cart/221662"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">NBP1-51575</div> <div class="images_customers"><div id="ss_prev_cav11" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-11" data-cycle-prev="#ss_prev_cav11" data-cycle-next="#ss_next_cav11" data-cycle-slides="div.big_thumb_cust_container" data-index=11 ><div class="big_thumb_cust_container"> <a href="/products/wnt-1-antibody-10c8_nbp1-51575" title="Immunocytochemistry/Immunofluorescence: Wnt-1 Antibody (10C8) [NBP1-51575] - Confocal immunofluorescence analysis of Hela (left) and 3T3-L1 (right) cells using WNT1 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye." class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images/Wnt-1-Antibody-10C8-Immunocytochemistry-Immunofluorescence-NBP1-51575-img0006.jpg" alt="Immunocytochemistry/ Immunofluorescence Wnt-1 Antibody (10C8) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/wnt-1-antibody-10c8_nbp1-51575" title="Immunohistochemistry-Paraffin: Wnt-1 Antibody (10C8) [NBP1-51575] - Analysis of human LAdrenal tissues using WNT1 mouse mAb." class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images/Wnt-1-Antibody-10C8-Immunohistochemistry-Paraffin-NBP1-51575-img0007.jpg" alt="Immunohistochemistry-Paraffin Wnt-1 Antibody (10C8) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/wnt-1-antibody-10c8_nbp1-51575" title="Western Blot: Wnt-1 Antibody (10C8) [NBP1-51575] - Analysis using WNT1 mouse mAb against NIH/3T3 (1), 3T3L1 (2) and Hela (3) cell lysate." class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images/Wnt-1-Antibody-10C8-Western-Blot-NBP1-51575-img0008.jpg" alt="Western Blot Wnt-1 Antibody (10C8) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav11" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-11" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/wnt-1-antibody-10c8_nbp1-51575#PublicationSection"> <div class="sprite_pubBook"></div> (2 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> ELISA, Flow, ICC/IF, IHC, IHC-P, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF5045"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/msx1-antibody_af5045" style="overflow: hidden; width: 280px;" title="MSX1 Antibody [Unconjugated]">MSX1 Antibody<br> [Unconjugated]</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="AF5045" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="AF5045" data-baseurl="https://www.novusbio.com" data-productid="413869"></div>--> <!-- <a href="/commerce/add-to-cart/413869"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">AF5045</div> <div class="images_customers"><div id="ss_prev_cav12" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-12" data-cycle-prev="#ss_prev_cav12" data-cycle-next="#ss_next_cav12" data-cycle-slides="div.big_thumb_cust_container" data-index=12 ><div class="big_thumb_cust_container"> <a href="/products/msx1-antibody_af5045" title="Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. Gels were loaded with 30 µg of whole cell lysate (WCL), 20 µg of cytoplasmic (Cyto), and 10 µg of nuclear extracts (Nuc). PVDF membrane was probed with 0.1 µg/mL Goat Anti-Human/Mouse MSX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5045) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band for MSX1 was detected at approximately 40 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images2/MSX1_AF5045_Western_Blot_5607.jpg" alt="Western Blot MSX1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/msx1-antibody_af5045" title="MSX1 was detected in immersion fixed paraffin-embedded sections of human ovarian cancer tissue using Goat Anti-Human/Mouse MSX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5045) at 0.3, 1.0 and 3.0 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell &amp;amp; Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images2/MSX1_AF5045_Immunohistochemistry_15258.jpg" alt="Immunohistochemistry MSX1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/msx1-antibody_af5045" title="Regulation of MSX1 expression is mediated by pSMAD1/5/8 in the human cap-stage tooth germs. (A–C) Immunostaining shows that MSX1 expression is abundant in dimethyl sulfoxide (DMSO)-treated human cap-stage tooth germs, dramatically reduced in dorsomorphin treated human cap-stage tooth germ, and unaltered in U0126 + SB203580 + SP600125 treated human cap-stage tooth germs. (D) A Western blot assay confirms the dramatically reduced expression of MSX1 in dorsomorphin treated human cap-stage tooth germs. Actin was used as the internal control. (E) Quantitative analysis of the Western blot assay. de, the dental epithelium; dm, the dental mesenchyme. Error bars represent SD. ***p &amp;lt; 0.001. Bar = 50 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/35211032), licensed under a CC-BY license. Not internally tested by R&amp;amp;D Systems." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images/af5045_human-mouse-msx1-affinity-purified-polyclonal-ab-41202412402511.jpg" alt="Western Blot MSX1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav12" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-12" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/msx1-antibody_af5045#PublicationSection"> <div class="sprite_pubBook"></div> (11 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> IHC, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF232"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/fgf-acidic-fgf1-antibody_af232" style="overflow: hidden; width: 280px;" title="FGF acidic/FGF1 Antibody [Unconjugated]">FGF acidic/FGF1<br> Antibody [Unconjugate</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="AF232" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="AF232" data-baseurl="https://www.novusbio.com" data-productid="413411"></div>--> <!-- <a href="/commerce/add-to-cart/413411"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">AF232</div> <div class="images_customers"><div id="ss_prev_cav13" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-13" data-cycle-prev="#ss_prev_cav13" data-cycle-next="#ss_next_cav13" data-cycle-slides="div.big_thumb_cust_container" data-index=13 ><div class="big_thumb_cust_container"> <a href="/products/fgf-acidic-fgf1-antibody_af232" title="FGF acidic/FGF1 was detected in immersion fixed paraffin-embedded sections of human breast using Goat Anti-Human FGF acidic/FGF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF232) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell &amp;amp; Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF_acidic_AF232_Immunohistochemistry_17183.jpg" alt="Immunohistochemistry FGF acidic/FGF1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/fgf-acidic-fgf1-antibody_af232" title="Simple Western lane view shows lysates of human brain (hypothalamus) tissue, loaded at 0.2&amp;amp;nbsp;mg/mL. A specific band was detected for FGF&amp;amp;nbsp;acidic/FGF1 at approximately 25&amp;amp;nbsp;kDa (as indicated) using&amp;amp;nbsp;2.5&amp;amp;nbsp;µg/mL of Goat Anti-Human FGF&amp;amp;nbsp;acidic/FGF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF232) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog&amp;amp;nbsp;# HAF109). This experiment was conducted under reducing&amp;amp;nbsp;conditions and using the 12-230 kDa separation system." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF_acidic_AF232_Simple_Western_17471.jpg" alt="Simple Western FGF acidic/FGF1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/fgf-acidic-fgf1-antibody_af232" title="Western blot shows lysates of human brain (hypothalamas) tissue and human heart tissue. PVDF membrane was probed with 0.25 µg/mL of Goat Anti-Human FGF acidic/FGF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF232) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for FGF acidic/FGF1 at approximately 16-17 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF_acidic_AF232_Western_Blot_18640.jpg" alt="Western Blot FGF acidic/FGF1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav13" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-13" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/fgf-acidic-fgf1-antibody_af232#PublicationSection"> <div class="sprite_pubBook"></div> (13 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> IHC, Neut, Simple Western, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB100-55393"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/gbx2-antibody_nb100-55393" style="overflow: hidden; width: 280px;" title="GBX2 Antibody">GBX2 Antibody</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="NB100-55393" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="NB100-55393" data-baseurl="https://www.novusbio.com" data-productid="65952"></div>--> <!-- <a href="/commerce/add-to-cart/65952"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">NB100-55393</div> <div class="images_customers"><div id="ss_prev_cav14" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-14" data-cycle-prev="#ss_prev_cav14" data-cycle-next="#ss_next_cav14" data-cycle-slides="div.big_thumb_cust_container" data-index=14 ><div class="big_thumb_cust_container"> <a href="/products/gbx2-antibody_nb100-55393" title="Immunohistochemistry-Paraffin: GBX2 Antibody [NB100-55393] - Staining of paraffin embedded Human Placenta at dilution of 5ug/ml. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images/GBX2-Antibody-Immunohistochemistry-Paraffin-NB100-55393-img0007.jpg" alt="Immunohistochemistry-Paraffin GBX2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/gbx2-antibody_nb100-55393" title="Immunohistochemistry-Paraffin: GBX2 Antibody [NB100-55393] - Negative Control showing staining of paraffin embedded Human Placenta, with no primary antibody." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images/GBX2-Antibody-Immunohistochemistry-Paraffin-NB100-55393-img0008.jpg" alt="Immunohistochemistry-Paraffin GBX2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/gbx2-antibody_nb100-55393" title="Immunocytochemistry/Immunofluorescence: GBX2 Antibody [NB100-55393] - Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml)." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images/GBX2-Antibody-Immunocytochemistry-Immunofluorescence-NB100-55393-img0009.jpg" alt="Immunocytochemistry/ Immunofluorescence GBX2 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav14" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-14" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/gbx2-antibody_nb100-55393#PublicationSection"> <div class="sprite_pubBook"></div> (3 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, PEP-ELISA, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-20486"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/ss18l1-antibody_nbp2-20486" style="overflow: hidden; width: 280px;" title="SS18L1 Antibody">SS18L1 Antibody</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="NBP2-20486" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="NBP2-20486" data-baseurl="https://www.novusbio.com" data-productid="330752"></div>--> <!-- <a href="/commerce/add-to-cart/330752"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">NBP2-20486</div> <div class="images_customers"><div id="ss_prev_cav15" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-15" data-cycle-prev="#ss_prev_cav15" data-cycle-next="#ss_next_cav15" data-cycle-slides="div.big_thumb_cust_container" data-index=15 ><div class="big_thumb_cust_container"> <a href="/products/ss18l1-antibody_nbp2-20486" title="Immunoprecipitation: SS18L1 Antibody [NBP2-20486] - Immunoprecipitation of CREST protein from MCF-7 whole cell extracts using 5 ug of CREST antibody [N1C2] . Western blot analysis was performed using CREST antibody [N1C2]. EasyBlot anti-Rabbit IgG was used as a secondary reagent." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/SS18L1-Antibody-Immunoprecipitation-NBP2-20486-img0007.jpg" alt="Immunoprecipitation SS18L1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/ss18l1-antibody_nbp2-20486" title="Immunohistochemistry-Paraffin: SS18L1 Antibody [NBP2-20486] - Immunohistochemical analysis of paraffin-embedded Huh-7 xenograft, using antibody at 1:500 dilution." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/SS18L1-Antibody-Immunohistochemistry-Paraffin-NBP2-20486-img0003.jpg" alt="Immunohistochemistry-Paraffin SS18L1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/ss18l1-antibody_nbp2-20486" title="Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/SS18L1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-20486-img0004.jpg" alt="Immunocytochemistry/ Immunofluorescence SS18L1 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav15" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-15" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, IP, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="MAB319"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/fgf-17-antibody-121630_mab319" style="overflow: hidden; width: 280px;" title="FGF-17 Antibody (121630)">FGF-17 Antibody<br> (121630)</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="MAB319" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="MAB319" data-baseurl="https://www.novusbio.com" data-productid="422850"></div>--> <!-- <a href="/commerce/add-to-cart/422850"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">MAB319</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-16" data-cycle-prev="#ss_prev_cav16" data-cycle-next="#ss_next_cav16" data-cycle-slides="div.big_thumb_cust_container" data-index=16 ><div class="big_thumb_cust_container"> <a href="/products/fgf-17-antibody-121630_mab319" title="FGF&amp;amp;#x2011;17 was detected in immersion fixed paraffin-embedded sections of human kidney using Human FGF&amp;amp;#x2011;17 Monoclonal Antibody (Catalog # MAB319) at 8 &amp;amp;micro;g/mL overnight at 4 &amp;amp;deg;C. Tissue was stained using the Anti-Mouse HRP-DAB Cell &amp;amp; Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific labeling was localized to the basement membrane supporting epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images2/FGF-17_MAB319_Immunohistochemistry_7365.jpg" alt="Immunohistochemistry FGF-17 Antibody (121630)" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/fgf-17-antibody-121630_mab319#PublicationSection"> <div class="sprite_pubBook"></div> (2 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> IHC, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB300-109"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109" style="overflow: hidden; width: 280px;" title="Tyrosine Hydroxylase Antibody">Tyrosine<br> Hydroxylase Antibody</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="NB300-109" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="NB300-109" data-baseurl="https://www.novusbio.com" data-productid="33373"></div>--> <!-- <a href="/commerce/add-to-cart/33373"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">NB300-109</div> <div class="images_customers"><div id="ss_prev_cav17" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-17" data-cycle-prev="#ss_prev_cav17" data-cycle-next="#ss_next_cav17" data-cycle-slides="div.big_thumb_cust_container" data-index=17 ><div class="big_thumb_cust_container"> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109" title="10x Magnification cryo-sections mouse: primary antibody: anti-rb TH: 1:500; o.n. secondary antibody: 1:500 dk-anti-rb DyLight488. IHC-Fr image submitted by a verified customer review." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/Tyrosine-Hydroxylase-Antibody-Immunohistochemistry-Frozen-NB300-109-img0023.jpg" alt="Immunohistochemistry-Frozen Tyrosine Hydroxylase Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109" title="Tyrosine hydroxylase immunoreactivity in the mushroom body. All panels show a right brain hemisphere (dorsal to the top, medial to the right), except panels M-O (posterior to the top). Tyrosine hydroxylase (TH) immunoreactivity is shown in magenta (A, D, G, J, M) and synapsin immunoreactivity in green (B, E, H, K, N). Corresponding merged images in C, F, I, L, O. Scale bars = 100 um. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0160531), licensed under a CC-BY license." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/Tyrosine-Hydroxylase-Antibody-Immunohistochemistry-NB300-109-img0028.jpg" alt="Immunohistochemistry Tyrosine Hydroxylase Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109" title="Tyrosine hydroxylase immunoreactivity in the central complex and the lateral accessory lobe. A-D: Frontal sections (immunoperoxidase preparations, dorsal to the top). E: Horizontal section (immunofluorescent preparation, posterior to the top). Scale bars = 100 um. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0160531), licensed under a CC-BY license." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/Tyrosine-Hydroxylase-Antibody-Immunohistochemistry-NB300-109-img0029.jpg" alt="Immunohistochemistry Tyrosine Hydroxylase Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav17" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-17" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109#ReviewsSection"> <div class="sprite_5Stars"></div> (7 Reviews</a>) </div> <div class="tiny"> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109#PublicationSection"> <div class="sprite_pubBook"></div> (230 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Ch, Dr, Hu, I, Ma, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> Dual ISH-IHC, ICC/IF, IHC-FrFl, IHC-WhMt, IHC, IHC-Fr, IHC-P, KO, Simple Western, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="H00002019-M04"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/en1-engrailed-1-antibody-3h2_h00002019-m04" style="overflow: hidden; width: 280px;" title="EN1/Engrailed 1 Antibody (3H2)">EN1/Engrailed 1<br> Antibody (3H2)</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="H00002019-M04" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="H00002019-M04" data-baseurl="https://www.novusbio.com" data-productid="47242"></div>--> <!-- <a href="/commerce/add-to-cart/47242"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">H00002019-M04</div> <div class="images_customers"><div id="ss_prev_cav18" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-18" data-cycle-prev="#ss_prev_cav18" data-cycle-next="#ss_next_cav18" data-cycle-slides="div.big_thumb_cust_container" data-index=18 ><div class="big_thumb_cust_container"> <a href="/products/en1-engrailed-1-antibody-3h2_h00002019-m04" title="ELISA: EN1/Engrailed 1 Antibody (3H2) [H00002019-M04] - Detection limit for recombinant GST tagged EN1 is approximately 1ng/ml as a capture antibody." class="cust_viewed_18" > <img loading="lazy" src="https://images.novusbio.com/images/EN1-Engrailed-1-Antibody-3H2-ELISA-H00002019-M04-img0002.jpg" alt="ELISA EN1/Engrailed 1 Antibody (3H2)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/en1-engrailed-1-antibody-3h2_h00002019-m04" title="Immunohistochemistry-Paraffin: EN1/Engrailed 1 Antibody (3H2) [H00002019-M04] - Analysis of monoclonal antibody to EN1 on formalin-fixed paraffin-embedded human cerebellum. Antibody concentration 3 ug/ml" class="cust_viewed_18" > <img loading="lazy" src="https://images.novusbio.com/images/EN1-Engrailed-1-Antibody-3H2-Immunohistochemistry-Paraffin-H00002019-M04-img0003.jpg" alt="Immunohistochemistry-Paraffin EN1/Engrailed 1 Antibody (3H2)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav18" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-18" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/en1-engrailed-1-antibody-3h2_h00002019-m04#PublicationSection"> <div class="sprite_pubBook"></div> (1 Publication</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> ELISA, IHC, IHC-P, IP, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="423-F8"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-mouse-fgf-8b-protein_423-f8" style="overflow: hidden; width: 280px;" title="Recombinant Human/Mouse FGF-8b Protein">Recombinant<br> Human/Mouse FGF-8b Pr</a> <!--<div class="purchase_cart_wrapper"> <div class="purchase_cart btnAdd" data-type="anc_btnonly" data-catbase="423-F8" data-return="recombinant-human-mouse-fgf-8b-protein_423-f8#datasheet" data-produrl="recombinant-human-mouse-fgf-8b-protein_423-f8" data-catnums="423-F8" data-baseurl="https://www.novusbio.com" data-productid="446692"></div>--> <!-- <a href="/commerce/add-to-cart/446692"><div class="purchase_cart"></div></a> --> <!--</div>--> </div><div class="sub-header">423-F8</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-19" data-cycle-prev="#ss_prev_cav19" data-cycle-next="#ss_next_cav19" data-cycle-slides="div.big_thumb_cust_container" data-index=19 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-mouse-fgf-8b-protein_423-f8" title="Recombinant Human/Mouse FGF-8b Protein" class="cust_viewed_19"> <img loading="lazy" src="/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png" alt="Recombinant Human/Mouse FGF-8b Protein" title="Recombinant Human/Mouse FGF-8b Protein" class=" big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> Bioactivity</div> </div> </div> </div></div> </div><div id="cav_next"><div class="sprite_rightArrow"></div></div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_reviews-publications"> <a id="reviews-publications"></a><a id="PublicationSection"></a><h2 class="greyHead2">Publications for FGF-8 (423-F8)(62)</h2><div class="ds_info"> <div>We have publications tested in 9 confirmed species: Human, Mouse, Rat, Avian - Quail, Chicken, Primate - Macaca mulatta (Rhesus Macaque), Rabbit, Xenopus, Zebrafish.<br /><br />We have publications tested in 5 applications: Bioassay, Cell Culture, Differentiation, In Ovo, In Vivo.<br /><br /><div class="align-right"> <button class="greybutton btn_width" name="novusreview" onclick="window.location='/publications'"; >Submit a Publication</button><br /> </div> </div><div> <div class="filterParent"> <div class="publications_filterList" id="pubapp"> <div class="blueHead">Filter By Application</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Bioassay"> <div style="display:inline;">Bioassay</div> (45)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Cell Culture"> <div style="display:inline;">Cell Culture</div> (6)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="Differentiation"> <div style="display:inline;">Differentiation</div> (4)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="In Ovo"> <div style="display:inline;">In Ovo</div> (1)</div><div class="filter_line"> <input type="checkbox" value="application" class="publication_filterCheckbox" data-filter="In Vivo"> <div style="display:inline;">In Vivo</div> (8)</div><div class="filter_clear" data-type="publication" data-filter="application">All Applications</div></div> <div class="publications_filterList" id="pubspec"> <div class="blueHead">Filter By Species</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Human"> <div style="display:inline;">Human</div> (28)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Mouse"> <div style="display:inline;">Mouse</div> (16)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Rat"> <div style="display:inline;">Rat</div> (4)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Avian - Quail"> <div style="display:inline;">Avian - Quail</div> (1)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Chicken"> <div style="display:inline;">Chicken</div> (8)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Primate - Macaca mulatta (Rhesus Macaque)"> <div style="display:inline;">Primate - Macaca mulatta (Rhesus Macaque)</div> (1)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Rabbit"> <div style="display:inline;">Rabbit</div> (1)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Xenopus"> <div style="display:inline;">Xenopus</div> (2)</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Zebrafish"> <div style="display:inline;">Zebrafish</div> (3)</div><div class="filter_clear" data-type="publication" data-filter="species">All Species</div></div> </div></div> <div class="clear"></div> <div id="publications_list">Showing Publications 1 - <span id="appcnt">10</span> of 62. <a class="pubs_showall">Show All 62 Publications.</a> <a class="pubs_collapse" style="display:none;">Collapse Publications.</a><table class="wide lightPad tablesorter" id="publications_list_table"> <thead> <tr> <th>Publications using 423-F8</th> <th>Applications</th> <th>Species</th> </tr> </thead> <tbody><tr class="lined revfil firstten" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38568193" target="_blank" rel="nofollow"> Karl, K;Del Piccolo, N;Light, T;Roy, T;Deduja, P;Ursachi, VC;Fafilek, B;Krejci, P;Hristova, K; Ligand bias underlies differential signaling of multiple FGFs via FGFR1 eLife 2024-04-03 [PMID: 38568193] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/38215943" target="_blank" rel="nofollow"> Miwata, T;Suga, H;Mitsumoto, K;Zhang, J;Hamada, Y;Sakakibara, M;Soen, M;Ozaki, H;Asano, T;Miyata, T;Kawaguchi, Y;Yasuda, Y;Kobayashi, T;Sugiyama, M;Onoue, T;Hagiwara, D;Iwama, S;Oyadomari, S;Arima, H; Simplified drug efficacy evaluation system for vasopressin neurodegenerative disease using mouse disease-specific induced pluripotent stem cells Peptides 2024-01-10 [PMID: 38215943] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/37843228" target="_blank" rel="nofollow"> Chen, Y;Kuang, J;Niu, Y;Zhu, H;Chen, X;So, KF;Xu, A;Shi, L; Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons Neural regeneration research 2024-04-01 [PMID: 37843228] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36626307" target="_blank" rel="nofollow"> S Wu, NC Hernandez, DW Sirkis, I Thomas-Wri, R Wade-Marti, R Schekman Unconventional secretion of alpha-synuclein mediated by palmitoylated DNAJC5 oligomers Elife, 2023-01-10;12(0):. 2023-01-10 [PMID: 36626307] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36459969" target="_blank" rel="nofollow"> CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendra, L Peng, H Oguro, J Kanaujiya, J Zou, D Sebesta, G Pratt, E Cross, J Blockwick, P Buxton, L Kinner-Bib, C Medura, C Tompkins, S Hughes, M Santiana, F Faghri, MA Nalls, D Vitale, S Ballard, YA Qi, DM Ramos, KM Anderson, J Stadler, P Narayan, J Papademetr, L Reilly, MP Nelson, S Aggarwal, LU Rosen, P Kirwan, V Pisupati, SL Coon, SW Scholz, T Priebe, M Öttl, J Dong, M Meijer, LJM Janssen, VS Lourenco, R van der Ka, D Crusius, D Paquet, AC Raulin, G Bu, A Held, BJ Wainger, RMC Gabriele, JM Casey, S Wray, D Abu-Bonsra, CL Parish, MS Beccari, DW Cleveland, E Li, IVL Rose, M Kampmann, C Calatayud, P Verstreken, L Heinrich, MY Chen, B Schüle, D Dou, ELF Holzbaur, MC Zanellati, R Basundra, M Deshmukh, S Cohen, R Khanna, M Raman, ZS Nevin, M Matia, J Van Lent, V Timmerman, BR Conklin, K Johnson Ch, K Zhang, S Funes, DA Bosco, L Erlebach, M Welzer, D Kronenberg, G Lyu, E Arenas, E Coccia, L Sarrafha, T Ahfeldt, JC Marioni, WC Skarnes, MR Cookson, ME Ward, FT Merkle A reference human induced pluripotent stem cell line for large-scale collaborative studies Cell Stem Cell, 2022-12-01;29(12):1685-1702.e22. 2022-12-01 [PMID: 36459969] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36288716" target="_blank" rel="nofollow"> JS Park, J Choi, L Cao, J Mohanty, Y Suzuki, A Park, D Baker, J Schlessing, S Lee Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein Cell Reports, 2022-10-25;41(4):111545. 2022-10-25 [PMID: 36288716] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Cell Culture" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36253431" target="_blank" rel="nofollow"> H Ozaki, H Suga, M Sakakibara, M Soen, N Miyake, T Miwata, S Taga, T Nagai, M Kano, K Mitsumoto, T Miyata, T Kobayashi, M Sugiyama, T Onoue, H Takagi, D Hagiwara, S Iwama, R Banno, G Iguchi, Y Takahashi, K Muguruma, H Inoue, H Arima Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state Scientific Reports, 2022-10-17;12(1):17381. 2022-10-17 [PMID: 36253431] (Cell Culture, Human) </a></td> <td valign="top">Cell Culture</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Cell Culture" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/36213683" target="_blank" rel="nofollow"> DS Lee, YJ Song, HR Gug, JH Lee, HS Bae, JC Park Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cells Stem Cells International, 2022-09-27;2022(0):1092184. 2022-09-27 [PMID: 36213683] (Cell Culture, Mouse) </a></td> <td valign="top">Cell Culture</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil firstten" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/35053442" target="_blank" rel="nofollow"> L Yu, M Toriseva, S Afshan, M Cangiano, V Fey, A Erickson, H Seikkula, K Alanen, P Taimen, O Ettala, M Nurmi, PJ Boström, M Kallajoki, J Tuomela, T Mirtti, IJ Beumer, M Nees, P Härkönen Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression Cancers, 2022-01-07;14(2):. 2022-01-07 [PMID: 35053442] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil firstten" data-application="Cell Culture" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/34687276" target="_blank" rel="nofollow"> N Hosaka, S Kanda, T Shimono, T Nishiyama Induction of gammadeltaT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cells Journal of Cellular and Molecular Medicine, 2021-10-23;0(0):. 2021-10-23 [PMID: 34687276] (Cell Culture, Mouse) </a></td> <td valign="top">Cell Culture</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/34439916" target="_blank" rel="nofollow"> M Restan Per, R Sharma, NZ Masri, SM Willerth 3D Bioprinting Mesenchymal Stem Cell-Derived Neural Tissues Using a Fibrin-Based Bioink Biomolecules, 2021-08-21;11(8):. 2021-08-21 [PMID: 34439916] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human, Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/33580754" target="_blank" rel="nofollow"> C Zhou, D Chen, J Ren, D Huang, R Li, H Luo, C Guan, Y Cao, W Wang FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex Journal of Cellular and Molecular Medicine, 2021-02-13;0(0):. 2021-02-13 [PMID: 33580754] (Bioassay, Human, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human, Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/33545081" target="_blank" rel="nofollow"> TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel, ND Socci, SJ Choi, S Zabierowsk, BN Dubose, EJ Hill, EV Mosharov, S Irion, MJ Tomishima, V Tabar, L Studer Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use Cell Stem Cell, 2021-02-04;28(2):343-355.e5. 2021-02-04 [PMID: 33545081] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Rat"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/33445073" target="_blank" rel="nofollow"> T Otsuka, PY Mengsteab, CT Laurencin Control of mesenchymal cell fate via application of FGF-8b in vitro Stem Cell Research, 2021-01-07;51(0):102155. 2021-01-07 [PMID: 33445073] (Bioassay, Rat) </a></td> <td valign="top">Bioassay</td> <td valign="top">Rat</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/32840960" target="_blank" rel="nofollow"> KX Liang, CK Kristianse, S Mostafavi, GH Vatne, GA Zantingh, A Kianian, C Tzoulis, LE Høyland, M Ziegler, RM Perez, J Furriol, Z Zhang, N Balafkan, Y Hong, R Siller, GJ Sullivan, LA Bindoff Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations EMBO Mol Med, 2020-08-25;0(0):e12146. 2020-08-25 [PMID: 32840960] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/32771055" target="_blank" rel="nofollow"> JL Goggi, L Qiu, MC Liao, S Khanapur, L Jiang, R Boominatha, SV Hartimath, P Cheng, FF Yong, V Soh, X Deng, YM Lin, A Haslop, PW Tan, X Zeng, JWL Lee, Z Zhang, P Sadasivam, EK Tan, SK Luthra, WD Shingleton, SKW Oh, L Zeng, EG Robins Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson&amp;#039;s disease Stem Cell Res Ther, 2020-08-08;11(1):347. 2020-08-08 [PMID: 32771055] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Cell Culture" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/32151030" target="_blank" rel="nofollow"> H Gla beta , P Neumann, A Pal, P Reinhardt, A Storch, J Sternecker, A Hermann Combined Dendritic and Axonal Deterioration Are Responsible for Motoneuronopathy in Patient-Derived Neuronal Cell Models of Chorea-Acanthocytosis Int J Mol Sci, 2020-03-05;21(5):. 2020-03-05 [PMID: 32151030] (Cell Culture, Human) </a></td> <td valign="top">Cell Culture</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Cell Culture" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/31776327" target="_blank" rel="nofollow"> S Mahajani, A Raina, C Fokken, S Kügler, M Bähr Homogenous generation of dopaminergic neurons from multiple hiPSC lines by transient expression of transcription factors Cell Death Dis, 2019-11-27;10(12):898. 2019-11-27 [PMID: 31776327] (Cell Culture, Human) </a></td> <td valign="top">Cell Culture</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/31186471" target="_blank" rel="nofollow"> S Westphal, T Gantert, C Kless, K Hüttinger, M Klingenspo, T Fromme Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes Sci Rep, 2019-06-11;9(1):8470. 2019-06-11 [PMID: 31186471] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/31080111" target="_blank" rel="nofollow"> I Allodi, J Nijssen, JA Benitez, C Schweingru, A Fuchs, G Bonvicini, M Cao, O Kiehn, E Hedlund Modeling Motor Neuron Resilience in ALS Using Stem Cells Stem Cell Reports, 2019-05-09;0(0):. 2019-05-09 [PMID: 31080111] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/30853899" target="_blank" rel="nofollow"> M Elkouris, G Kouroupi, A Vourvoukel, N Papagianna, V Kaltezioti, R Matsas, L Stefanis, M Xilouri, PK Politis Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson&amp;#039;s Disease Patients Front Cell Neurosci, 2019-02-22;13(0):58. 2019-02-22 [PMID: 30853899] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29910731" target="_blank" rel="nofollow"> G Collo, L Cavalleri, M Zoli, U Maskos, E Ratti, E Merlo Pich Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons Front Pharmacol, 2018-06-01;9(0):572. 2018-06-01 [PMID: 29910731] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29895168" target="_blank" rel="nofollow"> J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages Cell Transplant, 2018-06-13;0(0):9636897187803. 2018-06-13 [PMID: 29895168] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29720250" target="_blank" rel="nofollow"> X Hu, JW Lee, X Zheng, J Zhang, X Lin, Y Song, B Wang, X Hu, HH Chang, Y Chen, CP Lin, Y Zhang Efficient induction of functional ameloblasts from human keratinocyte stem cells Stem Cell Res Ther, 2018-05-02;9(1):126. 2018-05-02 [PMID: 29720250] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Differentiation, Differentiation" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29531524" target="_blank" rel="nofollow"> G Collo, L Cavalleri, F Bono, C Mora, S Fedele, RW Invernizzi, M Gennarelli, G Piovani, T Kunath, MJ Millan, E Merlo Pich, P Spano Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling Neural Plast., 2018-02-04;2018(0):4196961. 2018-02-04 [PMID: 29531524] (Differentiation, Differentiation, Human) </a></td> <td valign="top">Differentiation, Differentiation</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Rat"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29498713" target="_blank" rel="nofollow"> G Shall, M Menosky, S Decker, P Nethala, R Welchko, X Leveque, M Lu, M Sandstrom, U Hochgeschw, J Rossignol, G Dunbar Effects of Passage Number and Differentiation Protocol on the Generation of Dopaminergic Neurons from Rat Bone Marrow-Derived Mesenchymal Stem Cells Int J Mol Sci, 2018-03-02;19(3):. 2018-03-02 [PMID: 29498713] (Bioassay, Rat) </a></td> <td valign="top">Bioassay</td> <td valign="top">Rat</td> </tr><tr class="lined revfil hidden" data-application="Differentiation, Differentiation" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29378824" target="_blank" rel="nofollow"> A Ruzo, GF Croft, JJ Metzger, S Galgoczi, LJ Gerber, C Pellegrini, H Wang, M Fenner, S Tse, A Marks, C Nchako, AH Brivanlou Chromosomal instability during neurogenesis in Huntington&amp;#039;s disease Development, 2018-01-29;145(2):. 2018-01-29 [PMID: 29378824] (Differentiation, Differentiation, Human) </a></td> <td valign="top">Differentiation, Differentiation</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/29201062" target="_blank" rel="nofollow"> T Johansen, C Krabbe, SI Schmidt, AM Serrano, M Meyer Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells Stem Cells Int, 2017-10-22;2017(0):9605432. 2017-10-22 [PMID: 29201062] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/28270602" target="_blank" rel="nofollow"> AR Rodrigues, N Yakushiji-, Y Atsuta, G Andrey, P Schorderet, D Duboule, CJ Tabin Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells Proc. Natl. Acad. Sci. U.S.A, 2017-03-07;0(0):. 2017-03-07 [PMID: 28270602] (Bioassay, Chicken) </a></td> <td valign="top">Bioassay</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/28099414" target="_blank" rel="nofollow"> SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE Mnch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres Neurotoxic reactive astrocytes are induced by activated microglia Nature, 2017-01-18;541(7638):481-487. 2017-01-18 [PMID: 28099414] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/27881786" target="_blank" rel="nofollow"> Florian Wegner Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization J. Neurosci., 2016-11-23;36(47):12027-12043. 2016-11-23 [PMID: 27881786] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/27402846" target="_blank" rel="nofollow"> Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: Effects on Embryo Survival J Biol Chem, 2016-07-08;0(0):. 2016-07-08 [PMID: 27402846] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/27309537" target="_blank" rel="nofollow"> Daniel A Monti N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson&amp;#039;s Disease: Preliminary Clinical and Cell Line Data PLoS ONE, 2016-06-16;11(6):e0157602. 2016-06-16 [PMID: 27309537] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/27246266" target="_blank" rel="nofollow"> Eva Hedlund Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors Sci Rep, 2016-06-01;6(0):26448. 2016-06-01 [PMID: 27246266] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/26075383" target="_blank" rel="nofollow"> Chan W, Howe K, Clegg J, Guimond S, Price D, Turnbull J, Pratt T 2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline. PLoS ONE, 2015-06-15;10(6):e0130147. 2015-06-15 [PMID: 26075383] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/25517725" target="_blank" rel="nofollow"> Shen , Shih-Che, Shen , Ching-I, Lin , Ho, Chen , Chun-Jun, Chang , Chia-Yu, Chen , Sheng-Me, Lee , Hsiu-Chi, Lai , Ping-Sha, Su , Hong-Lin Susceptibility of human embryonic stem cell-derived neural cells to Japanese encephalitis virus infection. PLoS ONE, 2014-12-17;9(12):e114990. 2014-12-17 [PMID: 25517725] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/25516335" target="_blank" rel="nofollow"> Attia L, Schneider J, Yelin R, Schultheiss T Collective cell migration of the nephric duct requires FGF signaling. Dev Dyn, 2014-12-30;244(2):157-67. 2014-12-30 [PMID: 25516335] (Bioassay, Chicken) </a></td> <td valign="top">Bioassay</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/25109552" target="_blank" rel="nofollow"> Yamamoto-Shiraishi Y, Higuchi H, Yamamoto S, Hirano M, Kuroiwa A Etv1 and Ewsr1 cooperatively regulate limb mesenchymal Fgf10 expression in response to apical ectodermal ridge-derived fibroblast growth factor signal. Dev Biol, 2014-08-07;394(1):181-90. 2014-08-07 [PMID: 25109552] (Bioassay, Chicken) </a></td> <td valign="top">Bioassay</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/24633820" target="_blank" rel="nofollow"> Lewandowski J, Pursell T, Rabinowitz A, Vokes S Manipulating gene expression and signaling activity in cultured mouse limb bud cells. Dev Dyn, 2014-04-17;243(7):928-36. 2014-04-17 [PMID: 24633820] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/24549637" target="_blank" rel="nofollow"> Mong J, Panman L, Alekseenko Z, Kee N, Stanton L, Ericson J, Perlmann T Transcription factor-induced lineage programming of noradrenaline and motor neurons from embryonic stem cells. Stem Cells, 2014-03-01;32(3):609-22. 2014-03-01 [PMID: 24549637] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/24376815" target="_blank" rel="nofollow"> Ni , Na, Hu , Yaohua, Ren , Huixia, Luo , Chuanmin, Li , Peng, Wan , Jian-Bo, Su , Huanxing Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. PLoS ONE, 2013-12-20;8(12):e84504. 2013-12-20 [PMID: 24376815] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Zebrafish"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/24358375" target="_blank" rel="nofollow"> McCarroll , Matthew, Nechiporuk , Alex V Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish. PLoS ONE, 2013-12-17;8(12):e85087. 2013-12-17 [PMID: 24358375] (In Vivo, Zebrafish) </a></td> <td valign="top">In Vivo</td> <td valign="top">Zebrafish</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/23527072" target="_blank" rel="nofollow"> Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O MicroRNA-based promotion of human neuronal differentiation and subtype specification. PLoS ONE, 2013-03-18;8(3):e59011. 2013-03-18 [PMID: 23527072] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/20889570" target="_blank" rel="nofollow"> Tomlinson DC, Knowles MA Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am. J. Pathol., 2010-10-01;177(5):2379-86. 2010-10-01 [PMID: 20889570] (Bioassay, Human) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human</td> </tr><tr class="lined revfil hidden" data-application="Cell Culture" data-species="Rat"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/20711405" target="_blank" rel="nofollow"> Roelandt P, Pauwelyn KA, Sancho-Bru P Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells. PLoS ONE, 2010-08-11;5(8):e12101. 2010-08-11 [PMID: 20711405] (Cell Culture, Rat) </a></td> <td valign="top">Cell Culture</td> <td valign="top">Rat</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Avian - Quail"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17425953" target="_blank" rel="nofollow"> Nimmagadda S, Geetha-Loganathan P, Scaal M, Christ B, Huang R FGFs, Wnts and BMPs mediate induction of VEGFR-2 (Quek-1) expression during avian somite development. Dev. Biol., 2007-03-01;305(2):421-9. 2007-03-01 [PMID: 17425953] (In Vivo, Avian - Quail) </a></td> <td valign="top">In Vivo</td> <td valign="top">Avian - Quail</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17293457" target="_blank" rel="nofollow"> Salero E, Hatten ME Differentiation of ES cells into cerebellar neurons. Proc. Natl. Acad. Sci. U.S.A., 2007-02-09;104(8):2997-3002. 2007-02-09 [PMID: 17293457] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Zebrafish"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/17079270" target="_blank" rel="nofollow"> Shimizu T, Bae YK, Hibi M Cdx-Hox code controls competence for responding to Fgfs and retinoic acid in zebrafish neural tissue. Development, 2006-11-01;133(23):4709-19. 2006-11-01 [PMID: 17079270] (Bioassay, Zebrafish) </a></td> <td valign="top">Bioassay</td> <td valign="top">Zebrafish</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16943279" target="_blank" rel="nofollow"> Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development, 2006-08-30;133(19):3787-96. 2006-08-30 [PMID: 16943279] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16904661" target="_blank" rel="nofollow"> Tiecke E, Bangs F, Blaschke R, Farrell ER, Rappold G, Tickle C Expression of the short stature homeobox gene Shox is restricted by proximal and distal signals in chick limb buds and affects the length of skeletal elements. Dev. Biol., 2006-07-12;298(2):585-96. 2006-07-12 [PMID: 16904661] (In Vivo, Chicken) </a></td> <td valign="top">In Vivo</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16805795" target="_blank" rel="nofollow"> Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M Embryonic stem cell-derived neuron models of Parkinson&amp;apos;s disease exhibit delayed neuronal death. J. Neurochem., 2006-07-01;98(1):45-56. 2006-07-01 [PMID: 16805795] (Bioassay, Mouse) </a></td> <td valign="top">Bioassay</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16765936" target="_blank" rel="nofollow"> Hutson MR, Zhang P, Stadt HA, Sato AK, Li YX, Burch J, Creazzo TL, Kirby ML Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx. Dev. Biol., 2006-06-12;295(2):486-97. 2006-06-12 [PMID: 16765936] (Bioassay, Chicken) </a></td> <td valign="top">Bioassay</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Rat"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16243537" target="_blank" rel="nofollow"> Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol. Cell. Neurosci., 2005-10-21;31(2):251-62. 2005-10-21 [PMID: 16243537] (Bioassay, Rat) </a></td> <td valign="top">Bioassay</td> <td valign="top">Rat</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/16055560" target="_blank" rel="nofollow"> Delfini MC, Dubrulle J, Malapert P, Chal J, Pourquie O Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. Proc. Natl. Acad. Sci. U.S.A., 2005-07-29;102(32):11343-8. 2005-07-29 [PMID: 16055560] (In Vivo, Chicken) </a></td> <td valign="top">In Vivo</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Xenopus"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15975940" target="_blank" rel="nofollow"> Reversade B, Kuroda H, Lee H, Mays A, De Robertis EM Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development, 2005-06-23;132(15):3381-92. 2005-06-23 [PMID: 15975940] (In Vivo, Xenopus) </a></td> <td valign="top">In Vivo</td> <td valign="top">Xenopus</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Human, Primate - Macaca mulatta (Rhesus Macaque)"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/15310843" target="_blank" rel="nofollow"> Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A., 2004-08-13;101(34):12543-8. 2004-08-13 [PMID: 15310843] (Bioassay, Human, Primate - Macaca mulatta (Rhesus Macaque)) </a></td> <td valign="top">Bioassay</td> <td valign="top">Human, Primate - Macaca mulatta (Rhesus Macaque)</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Zebrafish"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12835397" target="_blank" rel="nofollow"> Wiellette EL, Sive H vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain. Development, 2003-08-01;130(16):3821-9. 2003-08-01 [PMID: 12835397] (In Vivo, Zebrafish) </a></td> <td valign="top">In Vivo</td> <td valign="top">Zebrafish</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12766771" target="_blank" rel="nofollow"> Gunhaga L, Marklund M, Sjodal M, Hsieh JC, Jessell TM, Edlund T Specification of dorsal telencephalic character by sequential Wnt and FGF signaling. Nat. Neurosci., 2003-07-01;6(7):701-7. 2003-07-01 [PMID: 12766771] (Bioassay, Chicken) </a></td> <td valign="top">Bioassay</td> <td valign="top">Chicken</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Xenopus"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12653248" target="_blank" rel="nofollow"> Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. Int. J. Dev. Biol., 2003-02-01;47(1):15-29. 2003-02-01 [PMID: 12653248] (In Vivo, Xenopus) </a></td> <td valign="top">In Vivo</td> <td valign="top">Xenopus</td> </tr><tr class="lined revfil hidden" data-application="Bioassay" data-species="Rabbit"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12419180" target="_blank" rel="nofollow"> Fischer A, Viebahn C, Blum M FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit. Curr. Biol., 2002-10-29;12(21):1807-16. 2002-10-29 [PMID: 12419180] (Bioassay, Rabbit) </a></td> <td valign="top">Bioassay</td> <td valign="top">Rabbit</td> </tr><tr class="lined revfil hidden" data-application="In Vivo" data-species="Mouse"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/12223417" target="_blank" rel="nofollow"> Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development, 2002-10-01;129(19):4613-25. 2002-10-01 [PMID: 12223417] (In Vivo, Mouse) </a></td> <td valign="top">In Vivo</td> <td valign="top">Mouse</td> </tr><tr class="lined revfil hidden" data-application="In Ovo" data-species="Chicken"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/11934859" target="_blank" rel="nofollow"> Alsan BH, 2019, Schultheiss TM Regulation of avian cardiogenesis by Fgf8 signaling. e0007247, 2002-04-01;129(8):1935-43. 2002-04-01 [PMID: 11934859] (In Ovo, Chicken) </a></td> <td valign="top">In Ovo</td> <td valign="top">Chicken</td> </tr><tr><td colspan="3" align="center"> <a class="pubs_showall">Show All 62 Publications.</a> <a class="pubs_collapse" style="display:none;">Collapse Publications.</a> </td></tr></tbody> </table> </div> </div><a id="ReviewsSection"></a> <h2 class="greyHead2">Review for <span>FGF-8 (423-F8)</span> (1) <span style="display:none;">5</span><span style="display:none;">1</span></h2> <div class="ds_info"> <div class="bottom15"> <strong>Average Rating: 5</strong> <div class="dsSprite_stars5"></div> (Based on 1 review) </div> <div> <div class="align-right"> <button class="greybutton btn_width" id="novusreview" name="novusreview" onclick="window.location='/reviews/423-F8'"; >Submit a Review</button><br /> </div> </div> <div class="blueHead"><strong>Reviews using 423-F8:</strong></div> <div class="filterParent"><div class="reviews_filterList"> <div class="blueHead">Filter by Applications</div><div class="filter_line"> <input type="checkbox" value="application" class="review_filterCheckbox" data-filter="Stem/Immune cell maintenance or differentiation "> <div style="display:inline;">Stem/Immune cell maintenance or differentiation </div> (1)</div><div class="filter_clear" data-type="review" data-filter="application">All Applications</div></div> <div class="reviews_filterList"> <div class="blueHead">Filter by Species</div><div class="filter_clear" data-type="review" data-filter="species">All Species</div></div></div><div id="reviews_list"> <table class="wide lightPad tablesorter" id="reviews_list_table"> <thead> <tr> <th>Images</th> <th>Ratings</th> <th>Applications</th> <th>Species</th> <th>Date</th> <th>Details</th> </tr> </thead> <tbody><tr class="top-lined revfil" data-rating="Excellent" data-application="Stem/Immune cell maintenance or differentiation " data-species=""> <td><a href="https://www.novusbio.com/sites/novusbio.com/files/reviews/review_423-f8_49486_0_0_0.jpg" title=" Picture shows some other cell differentiation, however it's difficult to say that was caused by the FGF-8 as there were other media factors used in the differentiation process." class="colorbox" title="Stem/Immune cell maintenance or differentiation " > <img loading="lazy" src="https://www.novusbio.com/sites/novusbio.com/files/reviews/review_423-f8_49486_0_0_0.jpg" class="reviews_imageBorder" width="75" alt="Stem/Immune cell maintenance or differentiation FGF-8 423-F8" /> <br/><span class="enlarge" href="#"><div class="dsSprite_magGlass"></div> Enlarge</span></a><meta content="09/11/2019" /> </td> <td> <span style="display:none;">5</span> <div class="dsSprite_stars5" content="5"></div> <div class="revby">reviewed by:<br />Verified Customer</div> </td> <td title="Stem/Immune cell maintenance or differentiation ">Stem/Immune cell maintenance or differentiation </td> <td></td> <td>09/11/2019</td> <td align="left"> <div class="dsSprite_expandReviews"><div class="expandReviewData">View</div></div> <div class="reviews_showMoreContent"> <div class="reviews_showMoreContentInner"><h2 class="greyHead">Summary</h2> <table class="even wide top"><tr><td class="text_bold">Application</td><td>Stem/Immune cell maintenance or differentiation </td></tr><tr><td class="text_bold">Lot</td><td>AFK2714121</td></tr><tr><td class="text_bold">Comments</td><td>Used for differentiation of human iPSC to dopaminergic neurons. easy to reconstitute and wasn't toxic to cells.</td></tr></table> </div> </div> </td> </tr></tbody> </table> </div><br /> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_protocols-faqs"> <a id="protocols-faqs"></a><h2 class="greyHead2">FAQs for FGF-8 (423-F8) (0)</h2> <a id="faqs"></a> <div class="ds_info">There are no specific FAQs related to this product. Read our general <a href="/support/faqs.html">customer & technical service FAQs.</a> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_supportresearch"> <a id="supportresearch"></a><table cellpadding="0" cellspacing="0"><tr></td></tr></table><h2 class="greyHead2">Additional FGF-8 Products</h2> <a id="addtlalphaprods"></a> <div class="ds_info"> <div> <span style="display:none;">Array 423-F8</span> <ul class="ds_noDotList"><li> <a href="/primary-antibodies/fgf-8">FGF-8 Antibodies</a></li><li> <a href="/elisa-kits/fgf-8">FGF-8 ELISA Kits</a></li><li> <a href="/lysates/fgf-8">FGF-8 Lysate</a></li><li> <a href="/proteins/fgf-8">FGF-8 Protein</a></li><li> <a href="/proteins-and-enzymes/fgf-8">FGF-8 Proteins and Enzymes</a></li></ul> </div> </div><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><h2 class="greyHead2">Blogs on FGF-8</h2> <a id="blogsect"></a> <div>There are no specific blogs for FGF-8, but you can <a href="/antibody-news/">read our latest blog posts.</div> <div class="clear"></div></div> </div></div><div class="grid_6"><div class="ds_blue_border marTop26 equalbottom"><div class="datasheet-ads-container" ><a href="https://www.bio-techne.com/resources/blogs/citation-widget-find-products-used-in-literature" target="_blank"><img loading="lazy" src="https://images.novusbio.com/design/citation-app-banner-349x119-v3.jpg" alt="Read our latest blog and use the new citation tool on bio-techne.com" title="new citation tool" class="datasheet-adzone" loading="lazy"></a></div><a id="jump_recommended"></a> <h2 class="greyHead2">Customers Who Bought This Also Bought</h2> <div class="text_center"><div class="images2"><div class="cycle-slideshow" data-cycle-fx="scrollHorz" data-cycle-timeout="0" data-cycle-prev="#ss_prev_sidebar" data-cycle-next="#ss_next_sidebar" data-cycle-slides="div.big_thumb_container" id="ds_customer_who_bought" ><div class="big_thumb_container" data-catnums="NB300-109"> <div class="img_container"> <a href="/products/tyrosine-hydroxylase-antibody_nb300-109" title="10x Magnification cryo-sections mouse: primary antibody: anti-rb TH: 1:500; o.n. secondary antibody: 1:500 dk-anti-rb DyLight488. IHC-Fr image submitted by a verified customer review." class="cust_bought" > <img loading="lazy" src="https://images.novusbio.com/images/Tyrosine-Hydroxylase-Antibody-Immunohistochemistry-Frozen-NB300-109-img0023.jpg" title="10x Magnification cryo-sections mouse: primary antibody: anti-rb TH: 1:500; o.n. secondary antibody: 1:500 dk-anti-rb DyLight488. IHC-Fr image submitted by a verified customer review." alt="10x Magnification cryo-sections mouse: primary antibody: anti-rb TH: 1:500; o.n. secondary antibody: 1:500 dk-anti-rb DyLight488. IHC-Fr image submitted by a verified customer review." class="big_thumb" /> </a> </div> <div class="caption_container"><a href="/products/tyrosine-hydroxylase-antibody_nb300-109">Tyrosine Hydroxylase Antibody</a> <br />NB300-109</div> <div style="text-align: right"><button class="greybutton" id="novusviewdatasheet" name="novusviewdatasheet" onclick="window.location='/products/tyrosine-hydroxylase-antibody_nb300-109';" >View Datasheet</button> </div> </div></div></div></div><div class="clear"></div><a id="jump_distributor"></a> <h2 class="greyHead2">Contact Information</h2> <div class="ds_info"> <div id="distributors"></div> </div> <div id="et_reload_trigger" style="display:none;">reload</div><h2 class="greyHead2">Product PDFs</h2><div class="silverHeadShort"> <span class="file"><a href="//aero.bio-techne.com/sds/pdf/423-f8" target="_blank" class="sprite_dsPDF"><span class="pdfSmaller">&nbsp;</span></a></span> <span class="download-file-text" ><a href="//aero.bio-techne.com/sds/pdf/423-f8" target="_blank" class="datasheet-download sdsFile">PDF SDS</a></span> </div><div class="silverHeadShort"> <span class="file"><a href="//resources.rndsystems.com/pdfs/datasheets/423-f8.pdf" target="_blank" class="sprite_dsPDF"><span class="pdfSmaller">&nbsp;</span></a></span> <span class="download-file-text" ><a href="//resources.rndsystems.com/pdfs/datasheets/423-f8.pdf" target="_blank" class="datasheet-download">PDF Datasheet</a></span> </div><div class="silverHeadShort"> <span class="file"><a href="mailto:novus@novusbio.com?subject=Request%20CofA%20for%20423-F8" class="sprite_newDocument"><span class="downloadBlank">&nbsp;</span></a></span> <span class="download-file-text"><a href="mailto:nb-technical@bio-techne.com?subject=Request%20CofA%20for%20423-F8&body=Specific%20catalog%20number(if multiple sizes):%0ALot%20Number:%0AAny%20additional%20products:">Request CofA</a></span> </div><h2 class="greyHead2">Calculators</h2> <div class="calc_wrapper"> <div class="dsSprite_calc"></div> <div class="fake_link" id="calc_reconstitution_link">Concentration Calculator</div> <div id="calc_reconstitution_wrapper" class="calc_function_wrapper"> <div class="calc_popup"> <div class="calc_close"> <div class="dsSprite_calc_close"></div> </div> <div class="calc_header">Concentration Calculator</div> <div id="reconstitution_calculator" class="calculator"> <div class="reconstitution_calculator_text" id="reconstitution_calculator_instructions"> <p>The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.</p> </div> <div class="calc_section"> <label for="reconstitution_calculator_volume" class="calculator_label">Volume</label> <input id="reconstitution_calculator_volume" name="reconstitution_calculator_volume" type="text" maxlength="16" placeholder="volume" class="calculator_input calculator_text"/> <select id="reconstitution_calculator_volume_unit" class="calculator_input calculator_select"> <option value="ml">ml</option> <option value="ul" selected="selected">ul</option> </select> </div> <span class="calculator_equals calculator_operator">=</span> <div class="calc_section"> <label for="reconstitution_calculator_mass" class="calculator_label">Mass</label> <input id="reconstitution_calculator_mass" name="reconstitution_calculator_mass" type="text" maxlength="16" placeholder="mass" class="calculator_input calculator_text"/> <select id="reconstitution_calculator_mass_unit" class="calculator_input calculator_select"> <option value="mg">mg</option> <option value="ug" selected="selected">ug</option> <option value="ng">ng</option> </select> </div> <span class="calculator_divide calculator_operator">&divide;</span> <div class="calc_section"> <label for="reconstitution_calculator_concentration" class="calculator_label">Concentration</label> <input id="reconstitution_calculator_concentration" name="reconstitution_calculator_concentration" type="text" maxlength="16" placeholder="concentration" class="calculator_input calculator_text"/> <select id="reconstitution_calculator_concentration_unit" class="calculator_input calculator_select"> <option value="mg/ml">mg/ml</option> <option value="ug/ml" selected="selected">ug/ml</option> <option value="ng/ml">ng/ml</option> </select> </div> <div id="reconstitution_foot" class="calc_section"> <input type="submit" value="Calculate" id="button_reconstitution_calculator_calculate" class="calculator_button"/> </div> </div> </div> </div> </div> <h2 class="greyHead2">Recent Reviews</h2><div class="review_summary"> <div class="review_summary_left"> <div class="review_large_number">5</div> <div class="dsSprite_stars5"></div> </div> <div class="review_summary_right"> <table> <tbody><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">5</div></td><td style="position:relative;width:155px;"><div class="review_bar star5" style="width:100%;"></div><div class="review_bar_value">1</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">4</div></td><td style="position:relative;width:155px;"><div class="review_bar star4" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">3</div></td><td style="position:relative;width:155px;"><div class="review_bar star3" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">2</div></td><td style="position:relative;width:155px;"><div class="review_bar star2" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr><tr><td><div class="dsSprite_emptyStar"></div><div class="review_summary_star_number">1</div></td><td style="position:relative;width:155px;"><div class="review_bar star1" style="width:0%;"></div><div class="review_bar_value">0</div></td></tr> </tbody> </table> </div> <hr /><div class="single_review"><div class="review_summary_image"><a href="//www.novusbio.com/sites/novusbio.com/files/reviews/review_423-f8_49486_0_0_0.jpg" title=" Picture shows some other cell differentiation, however it's difficult to say that was caused by the FGF-8 as there were other media factors used in the differentiation process." class="colorbox" title="Stem/Immune cell maintenance or differentiation " > <img loading="lazy" src="//www.novusbio.com/sites/novusbio.com/files/reviews/review_423-f8_49486_0_0_0.jpg" class="reviews_imageBorder" width="75" alt="Stem/Immune cell maintenance or differentiation FGF-8 423-F8" /> <br/><span class="enlarge" href="#"><div class="dsSprite_magGlass"></div> Enlarge</span></a></div> <div class="review_summary_right"><table> <tbody> <tr> <td><div class="dsSprite_stars5" content="5"></div></td> <td>Verified Customer<br />09/11/2019</td> </tr> <tr> <td class="review_summary_title">Application: </td> <td>Stem/Immune cell maintenance or differentiation <td> </tr> <tr> <td class="review_summary_title">Species: </td> <td></td> </tr> </tbody> </table> <div class="text_right" style="margin-bottom:-8px;"><a href="#ReviewsSection">read this review</a></div></div></div> <hr /><div class="align-right" style="margin-right:10px;"> <a href="#ReviewsSection"> <button class="greybutton btn_width">read all the reviews</button> </a> </div> </div><h2 class="greyHead2">Bioinformatics</h2> <div class="ds_info"> <a id="tab1bioinformatics"></a> <div> <table class="ds_list_right wide top"> <tr class="lined"> <td><strong>Gene Symbol</strong></td> <td><a href="/gene-name/FGF8">FGF8</a></td> </tr><tr class="grey-line-top"> <td><strong>Uniprot</strong></td> <td> <ul class="bioinf-list"><li><a target="_blank" href="http://www.uniprot.org/uniprot/?query=NP_006110%20%28human%29,%20NP_001159834%20%28mouse%29" rel="nofollow"><div class="sprite_newWindow">&nbsp;</div> NP_006110 (human), NP_001159834 (mouse)</a><span class="inline ">()</span></li> </ul> </td> </tr></table> </div> </div> </div> </div><div class="clear"></div> </div> </div> <div id="block-block-21" class="block block-block"> <div class="content"> <!-- Start of Invitations --> <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true" style="display: none;"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" aria-describedby="snapins_bodytext"> <img id="embeddedServiceAvatar" /> <span class="embeddedServiceTitleText" id="snapins_titletext">Need help?</span> <button type="button" id="closeInvite" class="embeddedServiceCloseIcon" aria-label="Exit invitation">&times;</button> </div> <div class="embeddedServiceInvitationBody"> <p id="snapins_bodytext">How can we help you?</p> </div> <div class="embeddedServiceInvitationFooter" aria-describedby="snapins_bodytext"> <button type="button" class="embeddedServiceActionButton" id="rejectInvite">Close</button> <button type="button" class="embeddedServiceActionButton" id="acceptInvite">Start Chat</button> </div> </div> </div> </div> </div> </div> </div> <div id="novus_footer_line"></div> <!-- </div> <div class="container_16" id="novus_footer"> <div id="novus_footer_social" class="grid_16 text_center"> <a href="//www.facebook.com/NovusBiologicals" target="_blank"><span class="sprite_facebook"></span></a> <a href="//twitter.com/novusbio" target="_blank"><span class="sprite_twitter"></span></a> <a href="//plus.google.com/b/114457663504514235763/114457663504514235763/posts" target="_blank"><span class="sprite_gplus"></span></a> <a href="//www.youtube.com/user/NovusBiologicals" target="_blank"><span class="sprite_youtube"></span></a> <a href="//www.linkedin.com/company/novus-biologicals-llc" target="_blank"><span class="sprite_linkedin"></span></a> <a href="//pinterest.com/novusbio/" target="_blank"><span class="sprite_pinterest"></span></a> </div> <div class="grid_16 text_center tableBlue_bar" id="novus_footer_register"> <span>Register with us - submit reviews and earn reward points for product discounts</span> <form action="/user/register" method="POST"> <input type="text" id="novus_footer_register_input" name="novus_footer_register_input"> <button id="novus_footer_register_submit">Submit</button> </form> </div> <div class="grid_11"><a href="/support/customer-service/terms.html">Terms &amp; Conditions</a> &nbsp; | &nbsp;<a href="/support/customer-service/privacy-policy.html">Privacy Policy</a> &nbsp; | &nbsp; <a href="/about/contact-us.html">Contact Us</a> &nbsp; | &nbsp; <a href="/novus-bio-sitemap.html">Sitemap</a></div> <div class="grid_5 text_right" id="novus_footer_end">&copy; Novus Biologicals, All Rights Reserved.</div> </div>--> </div> <div class="container_16"> <div id="footer"> <div class="grid_16 text_center"> <div class="fp_horzline"></div> </div> <div class="clear"></div> <div class="grid_16"> <table class="footer_boxes"> <tr> <th>Popular Products</th> <th>Company Information</th> <th>Support</th> <th>Stay Connected</th> </tr> <tr> <td> <ul class='links'><li><a href="/productsearch/novus">Antibodies</a></li><li><a href="/product-type/secondary-antibodies">Secondary Antibodies</a></li><li><a href="/product-type/isotype-controls">Isotype Controls</a></li><li><a href="/product-type/peptides-and-proteins">Proteins and Peptides</a></li><li><a href="/product-type/elisa-kits">ELISA Kits</a></li><li><a href="/samplesize">Sample Size</a></li><li><a href="https://www.novusbio.com/new-product-information-page.html">New Products</a></li> </ul> </td> <td> <ul class='links'><li><a href="/about.html">About Us</a></li><li><a href="https://www.bio-techne.com/about/careers">Careers</a></li><li><a href="/guarantee">Novus Guarantee</a></li><li><a href="/about/contact-us.html">Contact Us</a></li><li><a href="/about/novus-team.html">Our Team</a></li> </ul> </td> <td> <ul class='links'><li><a href="/support/technical-support.html">Technical Support</a></li><li><a href="/support/faqs.html">FAQs</a></li><li><a href="/webform/help-finding-antibodies">Help Finding Antibodies</a></li><li><a href="/support/support-by-application.html">Protocols</a></li> </ul> </td> <td id="footer_social_links"> </td> </tr> </table> </div> <div class="clear"></div> <div class="grid_16"> <div id="GTS_CONTAINER" style="float: right;margin-top: 10px;"></div> <div id="footer_officeinfo"> </div> <div class="fp_horzline"></div> <div class="footer_othersites"> <p>Visit our other sites</p> <a href="https://www.bio-techne.com/" target="_blank"><div class="fp_biotechne"></div></a> <a href="https://www.rndsystems.com/"><div class="fp_rnd"></div></a> <a href="https://www.novusbio.com/" target="_blank"><div class="fp_novus"></div></a> <a href="https://www.tocris.com/" target="_blank"><div class="fp_tocris"></div></a> <a href="https://www.bio-techne.com/brands/proteinsimple" target="_blank"><div class="fp_proteinSimple"></div></a> <a href="http://www.biospacific.com/" target="_blank"><div class="fp_biospacific"></div></a> <!--<a href="http://www.rnamedical.com/" target="_blank"><div class="fp_rna"></div></a>--> <a href="http://www.acdbio.com/" target="_blank"><div class="fp_acd"></div></a> <a href="https://www.rndheme.com/" target="_blank"><div class="fp_rndcc"></div></a> </div> <div class="text_center"> <div class="fp_horzline"></div> </div> <div class="copyright">&copy;2024 Novus Biologicals, All Rights Reserved.</div> <div class="footer_legal"> <ul class="links"><li class="menu-47946 first"><a href="/support/customer-service/privacy-policy.html" title="">Privacy Policy</a></li> <li class="menu-47956"><a href="/novus-bio-sitemap.html" title="">Sitemap</a></li> <li class="menu-47951"><a href="/about/contact-us.html" title="">Contact Us</a></li> <li class="menu-47941 last"><a href="/support/customer-service/terms.html" title="">Terms &amp; Conditions</a></li> </ul> </div> <div class="clear"></div> </div> </div> </div> <script type="text/javascript"> <!--//--><![CDATA[//><!-- var _hmt = _hmt || []; (function() { var hm = document.createElement("script"); hm.async = true; hm.defer = true; hm.src = "//hm.baidu.com/hm.js?35811d88f61196befe2e1f070a5036df"; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(hm, s); })(); //--><!]]> </script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"76fb58fb05","applicationID":"788348554,30870807","transactionName":"YFdbZBFZXxdWAhAMVlkdeFMXUV4KGAYBC1xFU01VPFxQEFYSDABcQw==","queueTime":23,"applicationTime":1237,"atts":"TBBYEllDTBk=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>

Pages： 1 2 3 4 5 6 7 8 9 10