CINXE.COM

medRxiv.org - the preprint server for Health Sciences

<!DOCTYPE html> <html lang="en" dir="ltr" xmlns="http://www.w3.org/1999/xhtml" xmlns:mml="http://www.w3.org/1998/Math/MathML"> <head prefix="og: http://ogp.me/ns# article: http://ogp.me/ns/article# book: http://ogp.me/ns/book#" > <!--[if IE]><![endif]--> <link rel="dns-prefetch" href="//d33xdlntwy0kbs.cloudfront.net" /> <link rel="dns-prefetch" href="//www.googletagmanager.com" /> <link rel="dns-prefetch" href="//rum-static.pingdom.net" /> <meta http-equiv="Content-Type" content="text/html; charset=utf-8" /> <meta name="twitter:card" content="summary" /> <meta name="twitter:site" content="@medrxivpreprint" /> <meta name="twitter:title" content="medRxiv" /> <meta name="twitter:description" content="the preprint service for Health Sciences" /> <link rel="shortcut icon" href="https://www.medrxiv.org/sites/default/files/images/favicon.ico" type="image/vnd.microsoft.icon" /> <meta name="viewport" content="width=device-width, initial-scale=1" /> <meta name="description" content="medRxiv - the preprint server for Health Sciences, operated by Cold Spring Harbor Laboratory, a research and educational institution" /> <meta name="generator" content="Drupal 7 (http://drupal.org)" /> <link rel="canonical" href="https://www.medrxiv.org/" /> <link rel="shortlink" href="https://www.medrxiv.org/" /> <title>medRxiv.org - the preprint server for Health Sciences</title> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__HZ-qMUtEfy3t2_CcrU8XBY06UykWM66UEaEJRxHJjoU__4bGJOYuuLPg6dlMcUBcYq4I8srDQ1Z7xIIlZlm12QIM__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <style type="text/css" media="all"> /* <![CDATA[ */ #sliding-popup.sliding-popup-bottom,#sliding-popup.sliding-popup-bottom .eu-cookie-withdraw-banner,.eu-cookie-withdraw-tab{background:gray}#sliding-popup.sliding-popup-bottom.eu-cookie-withdraw-wrapper{background:transparent}#sliding-popup .popup-content #popup-text h1,#sliding-popup .popup-content #popup-text h2,#sliding-popup .popup-content #popup-text h3,#sliding-popup .popup-content #popup-text p,.eu-cookie-compliance-secondary-button,.eu-cookie-withdraw-tab{color:#fff !important}.eu-cookie-withdraw-tab{border-color:#fff}.eu-cookie-compliance-more-button{color:#fff !important} /* ]]> */ </style> <!--[if lte IE 7]> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__ElJr3PIJEvw3qLXc1cnYiLj2G4KgDPSXFOfm6Phf8hw__JdWGm15cDWjsK6KrFlQVXQix9YgNeYysf22XZHj-Y-c__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <![endif]--> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__vP96nkAt3EeLU62QRdHXKZuS9tqQ1EMDJC_PSKd7hEk__lHjEjA8vesYocDHspzRjJD6B-seMDbxqo3imDh_XOlQ__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__fJyisBi_ctgWY7y5bbj1egD8NxwVot2RMlIsh8ycrEw__1DRWXQzAoLHKAicR_9AnF1-uoid-Dmi1-kB07HSe-7k__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <!--[if (lt IE 9)&(!IEMobile)]> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__XH6bpcI0f2dImc-p674DLCZtWBGb-QwxJK1YexVGtno__vUceGprdo5nIhV6DH93X7fI3r8RcTJbChbas9TQXeW4__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <![endif]--> <!--[if gte IE 9]><!--> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__2WBMox6sOrN42ss5lCnH7WWVRdFdJCxtTKnQJYRwTE4__yqNvNYLvMpjy3ffuJrjjm9uW2i-Me1c23KLYuWHaqio__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <!--<![endif]--> <link type="text/css" rel="stylesheet" href="https://www.medrxiv.org/sites/default/files/advagg_css/css__PnF_iSeOWgAJzGkPaUEVDxgWPcaChjxMdhV1Uy9wkic__rtQnXv8GOc-AsynbhzSlQBD_2lVxAkB6XEFUCK72qXc__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://d33xdlntwy0kbs.cloudfront.net/cshl_custom_medrxiv.css" media="all" /> <script type="text/javascript" src="https://www.medrxiv.org/sites/default/files/advagg_js/js__pLr-NK78ay59QifmKNmtslpYXxsCjzX3lUbvd1UscTE__E_rl9MaGSdu14D5lIJ_TM-BN_CCHKwiBu3XHi1GwR3E__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.js"></script> <script type="text/javascript" async="async" src="https://www.googletagmanager.com/gtag/js?id=G-0K57TCX5BY"></script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- /*! * yepnope1.5.4 * (c) WTFPL, GPLv2 */ (function(a,b,c){function d(a){return"[object Function]"==o.call(a)}function e(a){return"string"==typeof a}function f(){}function g(a){return!a||"loaded"==a||"complete"==a||"uninitialized"==a}function h(){var a=p.shift();q=1,a?a.t?m(function(){("c"==a.t?B.injectCss:B.injectJs)(a.s,0,a.a,a.x,a.e,1)},0):(a(),h()):q=0}function i(a,c,d,e,f,i,j){function k(b){if(!o&&g(l.readyState)&&(u.r=o=1,!q&&h(),l.onload=l.onreadystatechange=null,b)){"img"!=a&&m(function(){t.removeChild(l)},50);for(var d in y[c])y[c].hasOwnProperty(d)&&y[c][d].onload()}}var j=j||B.errorTimeout,l=b.createElement(a),o=0,r=0,u={t:d,s:c,e:f,a:i,x:j};1===y[c]&&(r=1,y[c]=[]),"object"==a?l.data=c:(l.src=c,l.type=a),l.width=l.height="0",l.onerror=l.onload=l.onreadystatechange=function(){k.call(this,r)},p.splice(e,0,u),"img"!=a&&(r||2===y[c]?(t.insertBefore(l,s?null:n),m(k,j)):y[c].push(l))}function j(a,b,c,d,f){return q=0,b=b||"j",e(a)?i("c"==b?v:u,a,b,this.i++,c,d,f):(p.splice(this.i++,0,a),1==p.length&&h()),this}function k(){var a=B;return a.loader={load:j,i:0},a}var l=b.documentElement,m=a.setTimeout,n=b.getElementsByTagName("script")[0],o={}.toString,p=[],q=0,r="MozAppearance"in l.style,s=r&&!!b.createRange().compareNode,t=s?l:n.parentNode,l=a.opera&&"[object Opera]"==o.call(a.opera),l=!!b.attachEvent&&!l,u=r?"object":l?"script":"img",v=l?"script":u,w=Array.isArray||function(a){return"[object Array]"==o.call(a)},x=[],y={},z={timeout:function(a,b){return b.length&&(a.timeout=b[0]),a}},A,B;B=function(a){function b(a){var a=a.split("!"),b=x.length,c=a.pop(),d=a.length,c={url:c,origUrl:c,prefixes:a},e,f,g;for(f=0;f<d;f++)g=a[f].split("="),(e=z[g.shift()])&&(c=e(c,g));for(f=0;f<b;f++)c=x[f](c);return c}function g(a,e,f,g,h){var i=b(a),j=i.autoCallback;i.url.split(".").pop().split("?").shift(),i.bypass||(e&&(e=d(e)?e:e[a]||e[g]||e[a.split("/").pop().split("?")[0]]),i.instead?i.instead(a,e,f,g,h):(y[i.url]?i.noexec=!0:y[i.url]=1,f.load(i.url,i.forceCSS||!i.forceJS&&"css"==i.url.split(".").pop().split("?").shift()?"c":c,i.noexec,i.attrs,i.timeout),(d(e)||d(j))&&f.load(function(){k(),e&&e(i.origUrl,h,g),j&&j(i.origUrl,h,g),y[i.url]=2})))}function h(a,b){function c(a,c){if(a){if(e(a))c||(j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}),g(a,j,b,0,h);else if(Object(a)===a)for(n in m=function(){var b=0,c;for(c in a)a.hasOwnProperty(c)&&b++;return b}(),a)a.hasOwnProperty(n)&&(!c&&!--m&&(d(j)?j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}:j[n]=function(a){return function(){var b=[].slice.call(arguments);a&&a.apply(this,b),l()}}(k[n])),g(a[n],j,b,n,h))}else!c&&l()}var h=!!a.test,i=a.load||a.both,j=a.callback||f,k=j,l=a.complete||f,m,n;c(h?a.yep:a.nope,!!i),i&&c(i)}var i,j,l=this.yepnope.loader;if(e(a))g(a,0,l,0);else if(w(a))for(i=0;i<a.length;i++)j=a[i],e(j)?g(j,0,l,0):w(j)?B(j):Object(j)===j&&h(j,l);else Object(a)===a&&h(a,l)},B.addPrefix=function(a,b){z[a]=b},B.addFilter=function(a){x.push(a)},B.errorTimeout=1e4,null==b.readyState&&b.addEventListener&&(b.readyState="loading",b.addEventListener("DOMContentLoaded",A=function(){b.removeEventListener("DOMContentLoaded",A,0),b.readyState="complete"},0)),a.yepnope=k(),a.yepnope.executeStack=h,a.yepnope.injectJs=function(a,c,d,e,i,j){var k=b.createElement("script"),l,o,e=e||B.errorTimeout;k.src=a;for(o in d)k.setAttribute(o,d[o]);c=j?h:c||f,k.onreadystatechange=k.onload=function(){!l&&g(k.readyState)&&(l=1,c(),k.onload=k.onreadystatechange=null)},m(function(){l||(l=1,c(1))},e),i?k.onload():n.parentNode.insertBefore(k,n)},a.yepnope.injectCss=function(a,c,d,e,g,i){var e=b.createElement("link"),j,c=i?h:c||f;e.href=a,e.rel="stylesheet",e.type="text/css";for(j in d)e.setAttribute(j,d[j]);g||(n.parentNode.insertBefore(e,n),m(c,0))}})(this,document); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- yepnope({ test: Modernizr.matchmedia, nope: '/sites/all/libraries/media-match/media.match.min.js' }); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- var _prum=[['id', '52e95df3abe53d2e33000000'], ['mark', 'firstbyte', (new Date()).getTime()]]; (function() { var s=document.getElementsByTagName('script')[0], p=document.createElement('script'); p.async='async'; p.src='//rum-static.pingdom.net/prum.min.js';s.parentNode.insertBefore(p,s);})(); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag("js", new Date());gtag("set", "developer_id.dMDhkMT", true);gtag("config", "G-0K57TCX5BY", {"groups":"default","anonymize_ip":true}); //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- jQuery.extend(Drupal.settings,{"basePath":"\/","pathPrefix":"","ajaxPageState":{"theme":"jcore_1","theme_token":"kJ88_r3vie665uZnNy7-aCEiILUbuUxl0iO6UQfCjrU"},"colorbox":{"opacity":"0.85","current":"{current} of {total}","previous":"\u00ab Prev","next":"Next \u00bb","close":"Close","maxWidth":"98%","maxHeight":"98%","fixed":true,"mobiledetect":true,"mobiledevicewidth":"480px"},"jcarousel":{"ajaxPath":"\/jcarousel\/ajax\/views"},"urlIsAjaxTrusted":{"\/":true},"highwireResponsive":{"enquire_enabled":1,"breakpoints_configured":1,"breakpoints":{"zero":"all and (min-width: 0px)","xsmall":"all and (min-width: 380px)","narrow":"all and (min-width: 768px) and (min-device-width: 768px), (max-device-width: 800px) and (min-width: 768px) and (orientation:landscape)","normal":"all and (min-width: 980px) and (min-device-width: 980px), all and (max-device-width: 1024px) and (min-width: 1024px) and (orientation:landscape)","wide":"all and (min-width: 1220px)"}},"eu_cookie_compliance":{"popup_enabled":1,"popup_agreed_enabled":0,"popup_hide_agreed":0,"popup_clicking_confirmation":1,"popup_scrolling_confirmation":false,"popup_html_info":"\u003Cdiv\u003E\n \u003Cdiv class=\u0022popup-content info\u0022\u003E\n \u003Cdiv id=\u0022popup-text\u0022\u003E\n \u003Cp\u003EWe use cookies on this site to enhance your user experience. By clicking any link on this page you are giving your consent for us to set cookies.\u003C\/p\u003E\n \u003C\/div\u003E\n \u003Cdiv id=\u0022popup-buttons\u0022\u003E\n \u003Cbutton type=\u0022button\u0022 role=\u0022dialog\u0022 aria-labelledby=\u0022Continue\u0022\n class=\u0022agree-button eu-cookie-compliance-default-button\u0022\u003EContinue\u003C\/button\u003E\n \u003Cbutton type=\u0022button\u0022 role=\u0022dialog\u0022 aria-labelledby=\u0022Find out more\u0022\n class=\u0022find-more-button eu-cookie-compliance-more-button\u0022\u003EFind out more\u003C\/button\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n\u003C\/div\u003E","use_mobile_message":false,"mobile_popup_html_info":"\u003Cdiv\u003E\n \u003Cdiv class=\u0022popup-content info\u0022\u003E\n \u003Cdiv id=\u0022popup-text\u0022\u003E\n \u003C\/div\u003E\n \u003Cdiv id=\u0022popup-buttons\u0022\u003E\n \u003Cbutton type=\u0022button\u0022 role=\u0022dialog\u0022 aria-labelledby=\u0022Continue\u0022\n class=\u0022agree-button eu-cookie-compliance-default-button\u0022\u003EContinue\u003C\/button\u003E\n \u003Cbutton type=\u0022button\u0022 role=\u0022dialog\u0022 aria-labelledby=\u0022Find out more\u0022\n class=\u0022find-more-button eu-cookie-compliance-more-button\u0022\u003EFind out more\u003C\/button\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n\u003C\/div\u003E","mobile_breakpoint":"768","popup_html_agreed":"\u003Cdiv\u003E\n \u003Cdiv class=\u0022popup-content agreed\u0022\u003E\n \u003Cdiv id=\u0022popup-text\u0022\u003E\n \u003Ch2\u003EThank you for accepting cookies\u003C\/h2\u003E\u003Cp\u003EYou can now hide this message or find out more about cookies.\u003C\/p\u003E \u003C\/div\u003E\n \u003Cdiv id=\u0022popup-buttons\u0022\u003E\n \u003Cbutton type=\u0022button\u0022 class=\u0022hide-popup-button eu-cookie-compliance-hide-button\u0022\u003EHide\u003C\/button\u003E\n \u003Cbutton type=\u0022button\u0022 class=\u0022find-more-button eu-cookie-compliance-more-button-thank-you\u0022 \u003EMore info\u003C\/button\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n\u003C\/div\u003E","popup_use_bare_css":false,"popup_height":"auto","popup_width":"100%","popup_delay":1000,"popup_link":"\/help\/cookie-policy","popup_link_new_window":1,"popup_position":null,"popup_language":"en","store_consent":false,"better_support_for_screen_readers":0,"reload_page":0,"domain":"","popup_eu_only_js":0,"cookie_lifetime":"365","cookie_session":false,"disagree_do_not_show_popup":0,"method":"default","whitelisted_cookies":"","withdraw_markup":"\u003Cbutton type=\u0022button\u0022 class=\u0022eu-cookie-withdraw-tab\u0022\u003EPrivacy settings\u003C\/button\u003E\n\u003Cdiv class=\u0022eu-cookie-withdraw-banner\u0022\u003E\n \u003Cdiv class=\u0022popup-content info\u0022\u003E\n \u003Cdiv id=\u0022popup-text\u0022\u003E\n \u003Cp\u003E\u0026lt;h2\u0026gt;We use cookies on this site to enhance your user experience\u0026lt;\/h2\u0026gt;\u0026lt;p\u0026gt;You have given your consent for us to set cookies.\u0026lt;\/p\u0026gt;\u003C\/p\u003E\n \u003C\/div\u003E\n \u003Cdiv id=\u0022popup-buttons\u0022\u003E\n \u003Cbutton type=\u0022button\u0022 class=\u0022eu-cookie-withdraw-button\u0022\u003EWithdraw consent\u003C\/button\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n\u003C\/div\u003E\n","withdraw_enabled":false},"googleanalytics":{"account":["G-0K57TCX5BY"],"trackOutbound":1,"trackMailto":1,"trackDownload":1,"trackDownloadExtensions":"7z|aac|arc|arj|asf|asx|avi|bin|csv|doc(x|m)?|dot(x|m)?|exe|flv|gif|gz|gzip|hqx|jar|jpe?g|js|mp(2|3|4|e?g)|mov(ie)?|msi|msp|pdf|phps|png|ppt(x|m)?|pot(x|m)?|pps(x|m)?|ppam|sld(x|m)?|thmx|qtm?|ra(m|r)?|sea|sit|tar|tgz|torrent|txt|wav|wma|wmv|wpd|xls(x|m|b)?|xlt(x|m)|xlam|xml|z|zip","trackColorbox":1},"jnl_biorxiv_styles":{"defaultJCode":"medrxiv"},"omega":{"layouts":{"primary":"normal","order":["narrow","normal","wide"],"queries":{"narrow":"all and (min-width: 768px) and (min-device-width: 768px), (max-device-width: 800px) and (min-width: 768px) and (orientation:landscape)","normal":"all and (min-width: 980px) and (min-device-width: 980px), all and (max-device-width: 1024px) and (min-width: 1024px) and (orientation:landscape)","wide":"all and (min-width: 1220px)"}}}}); //--><!]]> </script> <!--[if lt IE 9]><script src="http://html5shiv.googlecode.com/svn/trunk/html5.js"></script><![endif]--> </head> <body class="html front not-logged-in page-front3 hw-default-jcode-medrxiv"> <!-- Google Tag Manager --> <noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-P4HH5NV" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <script type="text/javascript">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0];var j=d.createElement(s);var dl=l!='dataLayer'?'&l='+l:'';j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;j.type='text/javascript';j.async=true;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-P4HH5NV');</script> <!-- End Google Tag Manager --> <div id="skip-link"> <a href="#main-content" class="element-invisible element-focusable">Skip to main content</a> </div> <div class="page clearfix page-box-shadows footer-borders panels-page panels-layout-onecol" id="page"> <header id="section-header" class="section section-header"> <div id="zone-branding" class="zone zone-branding clearfix print-display-block container-30"> <div class="grid-15 prefix-1 region region-branding print-display-block" id="region-branding"> <div class="region-inner region-branding-inner"> <div class="branding-data clearfix"> <div class="logo-img"> <h1 class="site-name"><a href="/" rel="home" class="active" data-icon-position="" data-hide-link-title="0"><img alt="medRxiv" src="https://www.medrxiv.org/sites/default/files/medrxiv_internal_logo.png" /></a></h1> </div> </div> <div class="block block-block block-1 block-block-1 odd block-without-title" id="block-block-1"> <div class="block-inner clearfix"> <div class="content clearfix"> <div class="cshl_logo"><a href="http://www.cshl.edu" target="_blank"><img src="/sites/default/files/medrxiv_pub_logos_2019.png" /></a></div> </div> </div> </div> </div> </div><div class="grid-11 suffix-1 region region-branding-second print-hidden" id="region-branding-second"> <div class="region-inner region-branding-second-inner"> <div class="block block-system block-menu block-main-menu block-system-main-menu odd block-without-title" id="block-system-main-menu"> <div class="block-inner clearfix"> <div class="content clearfix"> <nav class="menubar-nav"><ul class="menu" role="menu"><li class="first leaf" role="menuitem"><a href="/" title="" class="active" data-icon-position="" data-hide-link-title="0">Home</a></li> <li class="leaf" role="menuitem"><a href="/content/about-medrxiv" class="" data-icon-position="" data-hide-link-title="0">About</a></li> <li class="leaf" role="menuitem"><a href="/submit-a-manuscript" class="" data-icon-position="" data-hide-link-title="0">Submit</a></li> <li class="last leaf" role="menuitem"><a href="/content/alertsrss" title="" class="" data-icon-position="" data-hide-link-title="0">ALERTS / RSS</a></li> </ul></nav> </div> </div> </div> </div> </div> </div> <div id="zone-header" class="zone zone-header clearfix container-30"> </div> </header> <section id="section-content" class="section section-content"> <div id="zone-content" class="zone zone-content clearfix container-30"> <div class="grid-28 suffix-1 prefix-1 region region-content" id="region-content"> <div class="region-inner region-content-inner"> <a id="main-content"></a> <div class="block block-system block-main block-system-main odd block-without-title" id="block-system-main"> <div class="block-inner clearfix"> <div class="content clearfix"> <div class="panel-display panel-1col clearfix" > <div class="panel-panel panel-col"> <div><div class="panel-pane pane-block pane-block-3 center-me pane-block" > <div class="pane-content"> <div class="blood_logo"><img src="sites/default/files/medRxiv_homepage_logo.png" /></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-highwire-seach-quicksearch center-me" > <div class="pane-content"> <form class="highwire-quicksearch button-style-mini button-style-mini" action="/" method="post" id="highwire-search-quicksearch-form-0" accept-charset="UTF-8"><div><div class="form-item form-item-label-invisible form-type-textfield form-item-keywords"> <label class="element-invisible" for="search_rightsidebar_keywords_462985521">Search for this keyword </label> <input placeholder="Search " type="text" id="search_rightsidebar_keywords_462985521" name="keywords" value="" size="60" maxlength="128" class="form-text" /> </div> <div class="button-wrapper button-mini"><span class="icon-search"></span><input data-icon-only="1" data-font-icon="icon-search" data-icon-position="after" type="submit" id="search_rightsidebar_submit_1563514458" name="op" value="Search" class="form-submit" /></div><input type="hidden" name="form_build_id" value="form-9DtXHm5kDFZZoyH_u-W5AUhXGeRSymH3EE46JuhFq6w" /> <input type="hidden" name="form_id" value="highwire_search_quicksearch_form_0" /> </div></form> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-custom pane-1" > <div class="pane-content"> <p class="homepage-advanced-search" ><a href="/search">Advanced Search</a></p> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-panels-mini pane-biorxiv-subject-areas-table block-style-home" > <div class="pane-content"> <div class="panel-display panel-1col clearfix" id="mini-panel-biorxiv_subject_areas_table"> <div class="panel-panel panel-col"> <div><div class="panel-pane pane-snippet" id="subject-area-title"> <div class="pane-content"> <div class="snippet biorxiv-subject-areas-table-title" id="biorxiv-subject-areas-table-title"> <div class="snippet-content"> <b>Subject Areas</b> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-snippet" id="subject-view-all"> <div class="pane-content"> <div class="snippet biorxiv-subject-areas-view-papers" id="biorxiv-subject-areas-view-papers"> <div class="snippet-content"> <a href="/content/early/recent"><strong>All Articles</strong></a> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views pane-taxonomy-list-homepage-medrxiv" > <div class="pane-content"> <div class="view view-taxonomy-list-homepage-medrxiv view-id-taxonomy_list_homepage_medrxiv view-display-id-block homepage-custom-collections-list view-dom-id-e2ccf64e52f307b7a4bc1feebe8f846c"> <div class="view-content"> <div class="item-list highwire-views-col-list highwire-views-cols-3 clearfix"> <ul class=" highwire-views-col highwire-views-col-1 col-first"> <li class="views-row views-row-1 views-row-odd views-row-first"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/addiction-medicine" class="" data-icon-position="" data-hide-link-title="0">Addiction Medicine</a></span> </div></li> <li class="views-row views-row-2 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/allergy-and-immunology" class="" data-icon-position="" data-hide-link-title="0">Allergy and Immunology</a></span> </div></li> <li class="views-row views-row-3 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/anesthesia" class="" data-icon-position="" data-hide-link-title="0">Anesthesia</a></span> </div></li> <li class="views-row views-row-4 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/cardiovascular-medicine" class="" data-icon-position="" data-hide-link-title="0">Cardiovascular Medicine</a></span> </div></li> <li class="views-row views-row-5 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/dentistry-and-oral-medicine" class="" data-icon-position="" data-hide-link-title="0">Dentistry and Oral Medicine</a></span> </div></li> <li class="views-row views-row-6 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/dermatology" class="" data-icon-position="" data-hide-link-title="0">Dermatology</a></span> </div></li> <li class="views-row views-row-7 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/emergency-medicine" class="" data-icon-position="" data-hide-link-title="0">Emergency Medicine</a></span> </div></li> <li class="views-row views-row-8 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/endocrinology-including-diabetes-mellitus-and-metabolic-disease" class="" data-icon-position="" data-hide-link-title="0">Endocrinology (including Diabetes Mellitus and Metabolic Disease)</a></span> </div></li> <li class="views-row views-row-9 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/epidemiology" class="" data-icon-position="" data-hide-link-title="0">Epidemiology</a></span> </div></li> <li class="views-row views-row-10 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/forensic-medicine" class="" data-icon-position="" data-hide-link-title="0">Forensic Medicine</a></span> </div></li> <li class="views-row views-row-11 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/gastroenterology" class="" data-icon-position="" data-hide-link-title="0">Gastroenterology</a></span> </div></li> <li class="views-row views-row-12 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/genetic-and-genomic-medicine" class="" data-icon-position="" data-hide-link-title="0">Genetic and Genomic Medicine</a></span> </div></li> <li class="views-row views-row-13 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/geriatric-medicine" class="" data-icon-position="" data-hide-link-title="0">Geriatric Medicine</a></span> </div></li> <li class="views-row views-row-14 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/health-economics" class="" data-icon-position="" data-hide-link-title="0">Health Economics</a></span> </div></li> <li class="views-row views-row-15 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/health-informatics" class="" data-icon-position="" data-hide-link-title="0">Health Informatics</a></span> </div></li> <li class="views-row views-row-16 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/health-policy" class="" data-icon-position="" data-hide-link-title="0">Health Policy</a></span> </div></li> <li class="views-row views-row-17 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/health-systems-and-quality-improvement" class="" data-icon-position="" data-hide-link-title="0">Health Systems and Quality Improvement</a></span> </div></li> </ul> <ul class=" highwire-views-col highwire-views-col-2"> <li class="views-row views-row-18 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/hematology" class="" data-icon-position="" data-hide-link-title="0">Hematology</a></span> </div></li> <li class="views-row views-row-19 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/hiv-aids" class="" data-icon-position="" data-hide-link-title="0">HIV/AIDS</a></span> </div></li> <li class="views-row views-row-20 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/infectious_diseases" class="" data-icon-position="" data-hide-link-title="0">Infectious Diseases (except HIV/AIDS)</a></span> </div></li> <li class="views-row views-row-21 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/intensive-care-and-critical-care-medicine" class="" data-icon-position="" data-hide-link-title="0">Intensive Care and Critical Care Medicine</a></span> </div></li> <li class="views-row views-row-22 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/medical-education" class="" data-icon-position="" data-hide-link-title="0">Medical Education</a></span> </div></li> <li class="views-row views-row-23 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/medical-ethics" class="" data-icon-position="" data-hide-link-title="0">Medical Ethics</a></span> </div></li> <li class="views-row views-row-24 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/nephrology" class="" data-icon-position="" data-hide-link-title="0">Nephrology</a></span> </div></li> <li class="views-row views-row-25 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/neurology" class="" data-icon-position="" data-hide-link-title="0">Neurology</a></span> </div></li> <li class="views-row views-row-26 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/nursing" class="" data-icon-position="" data-hide-link-title="0">Nursing</a></span> </div></li> <li class="views-row views-row-27 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/nutrition" class="" data-icon-position="" data-hide-link-title="0">Nutrition</a></span> </div></li> <li class="views-row views-row-28 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/obstetrics-and-gynecology" class="" data-icon-position="" data-hide-link-title="0">Obstetrics and Gynecology</a></span> </div></li> <li class="views-row views-row-29 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/occupational-and-environmental-health" class="" data-icon-position="" data-hide-link-title="0">Occupational and Environmental Health</a></span> </div></li> <li class="views-row views-row-30 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/oncology" class="" data-icon-position="" data-hide-link-title="0">Oncology</a></span> </div></li> <li class="views-row views-row-31 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/ophthalmology" class="" data-icon-position="" data-hide-link-title="0">Ophthalmology</a></span> </div></li> <li class="views-row views-row-32 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/orthopedics" class="" data-icon-position="" data-hide-link-title="0">Orthopedics</a></span> </div></li> <li class="views-row views-row-33 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/otolaryngology" class="" data-icon-position="" data-hide-link-title="0">Otolaryngology</a></span> </div></li> <li class="views-row views-row-34 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/pain-medicine" class="" data-icon-position="" data-hide-link-title="0">Pain Medicine</a></span> </div></li> </ul> <ul class=" highwire-views-col highwire-views-col-3 col-last"> <li class="views-row views-row-35 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/palliative-medicine" class="" data-icon-position="" data-hide-link-title="0">Palliative Medicine</a></span> </div></li> <li class="views-row views-row-36 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/pathology" class="" data-icon-position="" data-hide-link-title="0">Pathology</a></span> </div></li> <li class="views-row views-row-37 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/pediatrics" class="" data-icon-position="" data-hide-link-title="0">Pediatrics</a></span> </div></li> <li class="views-row views-row-38 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/pharmacology-and-therapeutics" class="" data-icon-position="" data-hide-link-title="0">Pharmacology and Therapeutics</a></span> </div></li> <li class="views-row views-row-39 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/primary-care-research" class="" data-icon-position="" data-hide-link-title="0">Primary Care Research</a></span> </div></li> <li class="views-row views-row-40 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/psychiatry-and-clinical-psychology" class="" data-icon-position="" data-hide-link-title="0">Psychiatry and Clinical Psychology</a></span> </div></li> <li class="views-row views-row-41 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/public-and-global-health" class="" data-icon-position="" data-hide-link-title="0">Public and Global Health</a></span> </div></li> <li class="views-row views-row-42 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/radiology-and-imaging" class="" data-icon-position="" data-hide-link-title="0">Radiology and Imaging</a></span> </div></li> <li class="views-row views-row-43 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/rehabilitation-medicine-and-physical-therapy" class="" data-icon-position="" data-hide-link-title="0">Rehabilitation Medicine and Physical Therapy</a></span> </div></li> <li class="views-row views-row-44 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/respiratory-medicine" class="" data-icon-position="" data-hide-link-title="0">Respiratory Medicine</a></span> </div></li> <li class="views-row views-row-45 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/rheumatology" class="" data-icon-position="" data-hide-link-title="0">Rheumatology</a></span> </div></li> <li class="views-row views-row-46 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/sexual-and-reproductive-health" class="" data-icon-position="" data-hide-link-title="0">Sexual and Reproductive Health</a></span> </div></li> <li class="views-row views-row-47 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/sports-medicine" class="" data-icon-position="" data-hide-link-title="0">Sports Medicine</a></span> </div></li> <li class="views-row views-row-48 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/surgery" class="" data-icon-position="" data-hide-link-title="0">Surgery</a></span> </div></li> <li class="views-row views-row-49 views-row-odd"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/toxicology" class="" data-icon-position="" data-hide-link-title="0">Toxicology</a></span> </div></li> <li class="views-row views-row-50 views-row-even"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/transplantation" class="" data-icon-position="" data-hide-link-title="0">Transplantation</a></span> </div></li> <li class="views-row views-row-51 views-row-odd views-row-last"> <div class="views-field views-field-name"> <span class="field-content"><a href="/collection/urology" class="" data-icon-position="" data-hide-link-title="0">Urology</a></span> </div></li> </ul> </div> </div> <div class="view-footer"> <a href="/archive" class="view-by-month-link">View by Month</a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> <div class="region region-page-bottom" id="region-page-bottom"> <div class="region-inner region-page-bottom-inner"> </div> </div><script type="text/javascript" src="https://www.medrxiv.org/sites/default/files/advagg_js/js__bnwyEQSuZLC-kZnFqCi5iE02nOCzM7DjY7zYxcN9nsQ__VBiBT_qq_eHMMO2Q1rXK1u-hHff31XLUkmi9dgjuPeY__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.js"></script> <script type="text/javascript" src="https://d33xdlntwy0kbs.cloudfront.net/cshl_custom_medrxiv.js"></script> <script type="text/javascript" src="https://www.medrxiv.org/sites/default/files/advagg_js/js__BmqjBnkz3MgYCAoc25s1lDRMEjLhC3mEPVonUFIHi08__Unwv5-ZIuHBfFwytsjEx1niBVJ7n1T4lPws7VrkHXM4__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.js"></script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- function euCookieComplianceLoadScripts() {} //--><!]]> </script> <script type="text/javascript"> <!--//--><![CDATA[//><!-- var eu_cookie_compliance_cookie_name = ""; //--><!]]> </script> </body> </html>

Pages: 1 2 3 4 5 6 7 8 9 10