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Search results for: Riccardo Amadeo

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text-center" style="font-size:1.6rem;">Search results for: Riccardo Amadeo</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">29</span> A New Categorization of Image Quality Metrics Based on a Model of Human Quality Perception</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maria%20Grazia%20Albanesi">Maria Grazia Albanesi</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Amadeo"> Riccardo Amadeo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study presents a new model of the human image quality assessment process: the aim is to highlight the foundations of the image quality metrics proposed in literature, by identifying the cognitive/physiological or mathematical principles of their development and the relation with the actual human quality assessment process. The model allows to create a novel categorization of objective and subjective image quality metrics. Our work includes an overview of the most used or effective objective metrics in literature, and, for each of them, we underline its main characteristics, with reference to the rationale of the proposed model and categorization. From the results of this operation, we underline a problem that affects all the presented metrics: the fact that many aspects of human biases are not taken in account at all. We then propose a possible methodology to address this issue. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=eye-tracking" title="eye-tracking">eye-tracking</a>, <a href="https://publications.waset.org/abstracts/search?q=image%20quality%20assessment%20metric" title=" image quality assessment metric"> image quality assessment metric</a>, <a href="https://publications.waset.org/abstracts/search?q=MOS" title=" MOS"> MOS</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20of%20user%20experience" title=" quality of user experience"> quality of user experience</a>, <a href="https://publications.waset.org/abstracts/search?q=visual%20perception" title=" visual perception"> visual perception</a> </p> <a href="https://publications.waset.org/abstracts/8906/a-new-categorization-of-image-quality-metrics-based-on-a-model-of-human-quality-perception" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8906.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">411</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28</span> Cognitive Footprints: Analytical and Predictive Paradigm for Digital Learning</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marina%20Vicario">Marina Vicario</a>, <a href="https://publications.waset.org/abstracts/search?q=Amadeo%20Arg%C3%BCelles"> Amadeo Argüelles</a>, <a href="https://publications.waset.org/abstracts/search?q=Pilar%20G%C3%B3mez"> Pilar Gómez</a>, <a href="https://publications.waset.org/abstracts/search?q=Carlos%20Hern%C3%A1ndez"> Carlos Hernández</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, the Computer Research Network of the National Polytechnic Institute of Mexico proposes a paradigmatic model for the inference of cognitive patterns in digital learning systems. This model leads to metadata architecture useful for analysis and prediction in online learning systems; especially on MOOc's architectures. The model is in the design phase and expects to be tested through an institutional of courses project which is going to develop for the MOOc. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cognitive%20footprints" title="cognitive footprints">cognitive footprints</a>, <a href="https://publications.waset.org/abstracts/search?q=learning%20analytics" title=" learning analytics"> learning analytics</a>, <a href="https://publications.waset.org/abstracts/search?q=predictive%20learning" title=" predictive learning"> predictive learning</a>, <a href="https://publications.waset.org/abstracts/search?q=digital%20learning" title=" digital learning"> digital learning</a>, <a href="https://publications.waset.org/abstracts/search?q=educational%20computing" title=" educational computing"> educational computing</a>, <a href="https://publications.waset.org/abstracts/search?q=educational%20informatics" title=" educational informatics"> educational informatics</a> </p> <a href="https://publications.waset.org/abstracts/29913/cognitive-footprints-analytical-and-predictive-paradigm-for-digital-learning" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29913.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">477</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">27</span> An Approach to Physical Performance Analysis for Judo</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Stefano%20Frassinelli">Stefano Frassinelli</a>, <a href="https://publications.waset.org/abstracts/search?q=Alessandro%20Niccolai"> Alessandro Niccolai</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20E.%20Zich"> Riccardo E. Zich</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sport performance analysis is a technique that is becoming every year more important for athletes of every level. Many techniques have been developed to measure and analyse efficiently the performance of athletes in some sports, but in combat sports these techniques found in many times their limits, due to the high interaction between the two opponents during the competition. In this paper the problem will be framed. Moreover the physical performance measurement problem will be analysed and three different techniques to manage it will be presented. All the techniques have been used to analyse the performance of 22 high level Judo athletes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sport%20performance" title="sport performance">sport performance</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20performance" title=" physical performance"> physical performance</a>, <a href="https://publications.waset.org/abstracts/search?q=judo" title=" judo"> judo</a>, <a href="https://publications.waset.org/abstracts/search?q=performance%20coefficients" title=" performance coefficients"> performance coefficients</a> </p> <a href="https://publications.waset.org/abstracts/61556/an-approach-to-physical-performance-analysis-for-judo" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61556.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">413</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">26</span> The Buccal Fat Pad for Closure of Oroantral Communication</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Stefano%20A.%20Denes">Stefano A. Denes</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Tieghi"> Riccardo Tieghi</a>, <a href="https://publications.waset.org/abstracts/search?q=Giovanni%20Elia"> Giovanni Elia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The buccal fat pad is a well-established tool in oral and maxillofacial surgery and its use has proved of value for the closure of oroantral communications. Oroantral communication may be a common complication after sequestrectomy in "Bisphosphonate-related osteonecrosis of the jaws". We report a clinical case of a 70-year-old female patient in bisphosphonate therapy presented with right maxillary sinusitis and oroantral communication after implants insertion. The buccal fat pad was used to close the defect. The case had an uneventful postoperative healing without dehiscence, infection and necrosis. We postulate that the primary closure of the site with buccal fat pad may ensure a sufficient blood supply and adequate protection for an effective bone-healing response to occur. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=buccal%20fat%20pad" title="buccal fat pad">buccal fat pad</a>, <a href="https://publications.waset.org/abstracts/search?q=oroantral%20communication" title=" oroantral communication"> oroantral communication</a>, <a href="https://publications.waset.org/abstracts/search?q=oral%20surgery" title=" oral surgery"> oral surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=dehiscence" title=" dehiscence"> dehiscence</a> </p> <a href="https://publications.waset.org/abstracts/42870/the-buccal-fat-pad-for-closure-of-oroantral-communication" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42870.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">351</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">25</span> Electric Vehicles Charging Stations: Strategies and Algorithms Integrated in a Power-Sharing Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Loggia">Riccardo Loggia</a>, <a href="https://publications.waset.org/abstracts/search?q=Francesca%20Pizzimenti"> Francesca Pizzimenti</a>, <a href="https://publications.waset.org/abstracts/search?q=Francesco%20Lelli"> Francesco Lelli</a>, <a href="https://publications.waset.org/abstracts/search?q=Luigi%20Martirano"> Luigi Martirano</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Recent air emission regulations point toward the complete electrification of road vehicles. An increasing number of users are beginning to prefer full electric or hybrid, plug-in vehicle solutions, incentivized by government subsidies and the lower cost of electricity compared to gasoline or diesel. However, it is necessary to optimize charging stations so that they can simultaneously satisfy as many users as possible. The purpose of this paper is to present optimization algorithms that enable simultaneous charging of multiple electric vehicles while ensuring maximum performance in relation to the type of charging station. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electric%20vehicles" title="electric vehicles">electric vehicles</a>, <a href="https://publications.waset.org/abstracts/search?q=charging%20stations" title=" charging stations"> charging stations</a>, <a href="https://publications.waset.org/abstracts/search?q=sharing%20model" title=" sharing model"> sharing model</a>, <a href="https://publications.waset.org/abstracts/search?q=fast%20charging" title=" fast charging"> fast charging</a>, <a href="https://publications.waset.org/abstracts/search?q=car%20park" title=" car park"> car park</a>, <a href="https://publications.waset.org/abstracts/search?q=power%20profiles" title=" power profiles"> power profiles</a> </p> <a href="https://publications.waset.org/abstracts/151373/electric-vehicles-charging-stations-strategies-and-algorithms-integrated-in-a-power-sharing-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151373.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">154</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">24</span> Vibrations of Springboards: Mode Shape and Time Domain Analysis </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Stefano%20Frassinelli">Stefano Frassinelli</a>, <a href="https://publications.waset.org/abstracts/search?q=Alessandro%20Niccolai"> Alessandro Niccolai</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20E.%20Zich"> Riccardo E. Zich</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diving is an important Olympic sport. In this sport, the effective performance of the athlete is related to his capability to interact correctly with the springboard. In fact, the elevation of the jump and the correctness of the dive are influenced by the vibrations of the board. In this paper, the vibrations of the springboard will be analyzed by means of typical tools for vibration analysis: Firstly, a modal analysis will be done on two different models of the springboard, then, these two model and another one will be analyzed with a time analysis, done integrating the equations of motion od deformable bodies. All these analyses will be compared with experimental data measured on a real springboard by means of a 6-axis accelerometer; these measurements are aimed to assess the models proposed. The acquired data will be analyzed both in frequency domain and in time domain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=springboard%20analysis" title="springboard analysis">springboard analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=modal%20analysis" title=" modal analysis"> modal analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=time%20domain%20analysis" title=" time domain analysis"> time domain analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=vibrations" title=" vibrations"> vibrations</a> </p> <a href="https://publications.waset.org/abstracts/61559/vibrations-of-springboards-mode-shape-and-time-domain-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61559.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">460</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">23</span> Experimental Chip/Tool Temperature FEM Model Calibration by Infrared Thermography: A Case Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Angiuli">Riccardo Angiuli</a>, <a href="https://publications.waset.org/abstracts/search?q=Michele%20Giannuzzi"> Michele Giannuzzi</a>, <a href="https://publications.waset.org/abstracts/search?q=Rodolfo%20Franchi"> Rodolfo Franchi</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabriele%20Papadia"> Gabriele Papadia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Temperature knowledge in machining is fundamental to improve the numerical and FEM models used for the study of some critical process aspects, such as the behavior of the worked material and tool. The extreme conditions in which they operate make it impossible to use traditional measuring instruments; infrared thermography can be used as a valid measuring instrument for temperature measurement during metal cutting. In the study, a large experimental program on superduplex steel (ASTM A995 gr. 5A) cutting was carried out, the relevant cutting temperatures were measured by infrared thermography when certain cutting parameters changed, from traditional values to extreme ones. The values identified were used to calibrate a FEM model for the prediction of residual life of the tools. During the study, the problems related to the detection of cutting temperatures by infrared thermography were analyzed, and a dedicated procedure was developed that could be used during similar processing. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=machining" title="machining">machining</a>, <a href="https://publications.waset.org/abstracts/search?q=infrared%20thermography" title=" infrared thermography"> infrared thermography</a>, <a href="https://publications.waset.org/abstracts/search?q=FEM" title=" FEM"> FEM</a>, <a href="https://publications.waset.org/abstracts/search?q=temperature%20measurement" title=" temperature measurement"> temperature measurement</a> </p> <a href="https://publications.waset.org/abstracts/92363/experimental-chiptool-temperature-fem-model-calibration-by-infrared-thermography-a-case-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/92363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> Networked Radar System to Increase Safety of Urban Railroad Crossing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sergio%20Saponara">Sergio Saponara</a>, <a href="https://publications.waset.org/abstracts/search?q=Luca%20Fanucci"> Luca Fanucci</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Cassettari"> Riccardo Cassettari</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruggero%20Piernicola"> Ruggero Piernicola</a>, <a href="https://publications.waset.org/abstracts/search?q=Marco%20Righetto"> Marco Righetto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper presents an innovative networked radar system for detection of obstacles in a railway level crossing scenario. This Monitoring System (MS) is able to detect moving or still obstacles within the railway level crossing area automatically, avoiding the need of human presence for surveillance. The MS is also connected to the National Railway Information and Signaling System to communicate in real-time the level crossing status. The architecture is compliant with the highest Safety Integrity Level (SIL4) of the CENELEC standard. The number of radar sensors used is configurable at set-up time and depends on how large the level crossing area can be. At least two sensors are expected and up four can be used for larger areas. The whole processing chain that elaborates the output sensor signals, as well as the communication interface, is fully-digital, was designed in VHDL code and implemented onto a Xilinx Virtex 6. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=radar%20for%20safe%20mobility" title="radar for safe mobility">radar for safe mobility</a>, <a href="https://publications.waset.org/abstracts/search?q=railroad%20crossing" title=" railroad crossing"> railroad crossing</a>, <a href="https://publications.waset.org/abstracts/search?q=railway" title=" railway"> railway</a>, <a href="https://publications.waset.org/abstracts/search?q=transport%20safety" title=" transport safety"> transport safety</a> </p> <a href="https://publications.waset.org/abstracts/31337/networked-radar-system-to-increase-safety-of-urban-railroad-crossing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31337.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">480</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> Business-to-Business Deals Based on a Co-Utile Collaboration Mechanism: Designing Trust Company of the Future</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Bonazzi">Riccardo Bonazzi</a>, <a href="https://publications.waset.org/abstracts/search?q=Micha%C3%ABl%20Poli"> Michaël Poli</a>, <a href="https://publications.waset.org/abstracts/search?q=Abeba%20Nigussie%20Turi"> Abeba Nigussie Turi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents an applied research of a new module for the financial administration and management industry, Personalizable and Automated Checklists Integrator, Overseeing Legal Investigations (PACIOLI). It aims at designing the business model of the trust company of the future. By identifying the key stakeholders, we draw a general business process design of the industry. The business model focuses on disintermediating the traditional form of business through the new technological solutions of a software company based in Switzerland and hence creating a new interactive platform. The key stakeholders of this interactive platform are identified as IT experts, legal experts, and the New Edge Trust Company (NATC). The mechanism we design and propose has a great importance in improving the efficiency of the financial business administration and management industry, and it also helps to foster the provision of high value added services in the sector. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=new%20edge%20trust%20company" title="new edge trust company">new edge trust company</a>, <a href="https://publications.waset.org/abstracts/search?q=business%20model%20design" title=" business model design"> business model design</a>, <a href="https://publications.waset.org/abstracts/search?q=automated%20checklists" title=" automated checklists"> automated checklists</a>, <a href="https://publications.waset.org/abstracts/search?q=financial%20technology" title=" financial technology"> financial technology</a> </p> <a href="https://publications.waset.org/abstracts/71678/business-to-business-deals-based-on-a-co-utile-collaboration-mechanism-designing-trust-company-of-the-future" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/71678.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">372</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Naturally Occurring Chemicals in Biopesticides&#039; Resistance Control through Molecular Topology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Zanni">Riccardo Zanni</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Galvez-Llompart"> Maria Galvez-Llompart</a>, <a href="https://publications.waset.org/abstracts/search?q=Ramon%20Garcia-Domenech"> Ramon Garcia-Domenech</a>, <a href="https://publications.waset.org/abstracts/search?q=Jorge%20Galvez"> Jorge Galvez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biopesticides, such as naturally occurring chemicals, pheromones, fungi, bacteria and insect predators are often a winning choice in crop protection because of their environmental friendly profile. They are considered to have lower toxicity than traditional pesticides. After almost a century of pesticides use, resistances to traditional insecticides are wide spread, while those to bioinsecticides have raised less attention, and resistance management is frequently neglected. This seems to be a crucial mistake since resistances have already occurred for many marketed biopesticides. With an eye to the future, we present here a selection of new natural occurring chemicals as potential bioinsecticides. The molecules were selected using a consolidated mathematical paradigm called molecular topology. Several QSAR equations were depicted and subsequently applied for the virtual screening of hundred thousands molecules of natural origin, which resulted in the selection of new potential bioinsecticides. The most innovative aspect of this work does not only reside in the importance of the identification of new molecules overcoming biopesticides’ resistances, but on the possibility to promote shared knowledge in the field of green chemistry through this unique in silico discipline named molecular topology. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=green%20chemistry" title="green chemistry">green chemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=QSAR" title=" QSAR"> QSAR</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20topology" title=" molecular topology"> molecular topology</a>, <a href="https://publications.waset.org/abstracts/search?q=biopesticide" title=" biopesticide"> biopesticide</a> </p> <a href="https://publications.waset.org/abstracts/60275/naturally-occurring-chemicals-in-biopesticides-resistance-control-through-molecular-topology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60275.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">314</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> Skin Substitutes for Wound Healing: An Advanced Formulation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20Stefania">Pennisi Stefania</a>, <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20Graziella"> Giuffrida Graziella</a>, <a href="https://publications.waset.org/abstracts/search?q=Coppa%20Federica"> Coppa Federica</a>, <a href="https://publications.waset.org/abstracts/search?q=Iannello%20Giulia"> Iannello Giulia</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20Simone"> Cartelli Simone</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20Riccardo"> Lo Faro Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20Greta"> Ferruggia Greta</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20Maria%20Violetta"> Brundo Maria Violetta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Tissue engineering aims to develop advanced medical devices to restore normal functions of damaged tissue. These devices, even more effective than conventional methods, are called skin substitutes and are configured as drugs to be applied to the damaged area, to heal extensive and deep wounds which could otherwise lead to chronic wounds lasting over time. Among the variety of commercially available skin substitutes, those that have proven to be most effective are those consisting of a bilayer scaffold. The aim of our research was to design a skin substitute which can promote cell proliferation, cell migration and angiogenesis, and which can guarantee timely closure of the wound with satisfactory aesthetic results, in order to avoid the patient excessive pain, risk of contracting infections and long-term hospitalization. The product was tested in vitro using the Scratch Assay. The assay was carried out both on the matrix modified with hyaluronic acid and on the matrix based only on collagen. In both cases, after 48 hours of exposure the wound scratch was almost completely closed in treated cells compared to untreated control. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=collagen" title="collagen">collagen</a>, <a href="https://publications.waset.org/abstracts/search?q=hyaluronic%20acid" title=" hyaluronic acid"> hyaluronic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=scratch-%20wound-healing%20assay" title=" scratch- wound-healing assay"> scratch- wound-healing assay</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20regeneration" title=" tissue regeneration"> tissue regeneration</a> </p> <a href="https://publications.waset.org/abstracts/187381/skin-substitutes-for-wound-healing-an-advanced-formulation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187381.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">25</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> A Virtual Set-Up to Evaluate Augmented Reality Effect on Simulated Driving</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alicia%20Yanadira%20Nava%20Fuentes">Alicia Yanadira Nava Fuentes</a>, <a href="https://publications.waset.org/abstracts/search?q=Ilse%20Cervantes%20Camacho"> Ilse Cervantes Camacho</a>, <a href="https://publications.waset.org/abstracts/search?q=Amadeo%20Jos%C3%A9%20Arg%C3%BCelles%20Cruz"> Amadeo José Argüelles Cruz</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Mar%C3%ADa%20Balboa%20Verduzco"> Ana María Balboa Verduzco</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Augmented reality promises being present in future driving, with its immersive technology let to show directions and maps to identify important places indicating with graphic elements when the car driver requires the information. On the other side, driving is considered a multitasking activity and, for some people, a complex activity where different situations commonly occur that require the immediate attention of the car driver to make decisions that contribute to avoid accidents; therefore, the main aim of the project is the instrumentation of a platform with biometric sensors that allows evaluating the performance in driving vehicles with the influence of augmented reality devices to detect the level of attention in drivers, since it is important to know the effect that it produces. In this study, the physiological sensors EPOC X (EEG), ECG06 PRO and EMG Myoware are joined in the driving test platform with a Logitech G29 steering wheel and the simulation software City Car Driving in which the level of traffic can be controlled, as well as the number of pedestrians that exist within the simulation obtaining a driver interaction in real mode and through a MSP430 microcontroller achieves the acquisition of data for storage. The sensors bring a continuous analog signal in time that needs signal conditioning, at this point, a signal amplifier is incorporated due to the acquired signals having a sensitive range of 1.25 mm/mV, also filtering that consists in eliminating the frequency bands of the signal in order to be interpretative and without noise to convert it from an analog signal into a digital signal to analyze the physiological signals of the drivers, these values are stored in a database. Based on this compilation, we work on the extraction of signal features and implement K-NN (k-nearest neighbor) classification methods and decision trees (unsupervised learning) that enable the study of data for the identification of patterns and determine by classification methods different effects of augmented reality on drivers. The expected results of this project include are a test platform instrumented with biometric sensors for data acquisition during driving and a database with the required variables to determine the effect caused by augmented reality on people in simulated driving. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=augmented%20reality" title="augmented reality">augmented reality</a>, <a href="https://publications.waset.org/abstracts/search?q=driving" title=" driving"> driving</a>, <a href="https://publications.waset.org/abstracts/search?q=physiological%20signals" title=" physiological signals"> physiological signals</a>, <a href="https://publications.waset.org/abstracts/search?q=test%20platform" title=" test platform"> test platform</a> </p> <a href="https://publications.waset.org/abstracts/145037/a-virtual-set-up-to-evaluate-augmented-reality-effect-on-simulated-driving" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/145037.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">141</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Effectiveness of Opuntia ficus indica Cladodes Extract for Wound-Healing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20Graziella">Giuffrida Graziella</a>, <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20Stefania"> Pennisi Stefania</a>, <a href="https://publications.waset.org/abstracts/search?q=Coppa%20Federica"> Coppa Federica</a>, <a href="https://publications.waset.org/abstracts/search?q=Iannello%20Giulia"> Iannello Giulia</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20Simone"> Cartelli Simone</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20Riccardo"> Lo Faro Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20Greta"> Ferruggia Greta</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20Maria%20Violetta"> Brundo Maria Violetta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cladode chemical composition may vary according to soil factors, cultivation season, and plant age. The primary metabolites of cladodes are water, carbohydrates, and proteins. The carbohydrates in cladodes are divided into two types: structural and storage. Polysaccharides from Opuntia ficus‐indica (L.) Mill plants build molecular networks with the capacity to retain water; thus, they act as mucoprotective agents. Mucilage is the main polysaccharide of cladodes; it contains polymers of β‐d‐galacturonic acid bound in positions (1–4) and traces of R‐linked l‐rhamnose (1-2). Mucilage regulates both the cell water content during prolonged drought and the calcium flux in the plant cells. The in vitro analysis of keratinocytes in monolayer, through the scratch-wound-healing assay, provided promising results. After 48 hours of exposure, the wound scratch was almost completely closed in cells treated with cladode extract. After 72 hours, the treated cells reached complete confluence, while in the untreated cells (negative control) the confluence was reached after 96 hours. We also added a positive control group of cells treated with colchicine, which inhibited wound closure for a more comprehensive analysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cladodes" title="cladodes">cladodes</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolites" title=" metabolites"> metabolites</a>, <a href="https://publications.waset.org/abstracts/search?q=polysaccharide" title=" polysaccharide"> polysaccharide</a>, <a href="https://publications.waset.org/abstracts/search?q=scratch-wound-healing%20assay" title=" scratch-wound-healing assay"> scratch-wound-healing assay</a> </p> <a href="https://publications.waset.org/abstracts/187380/effectiveness-of-opuntia-ficus-indica-cladodes-extract-for-wound-healing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187380.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">53</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> A Spatial Repetitive Controller Applied to an Aeroelastic Model for Wind Turbines</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Fratini">Riccardo Fratini</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Santini"> Riccardo Santini</a>, <a href="https://publications.waset.org/abstracts/search?q=Jacopo%20Serafini"> Jacopo Serafini</a>, <a href="https://publications.waset.org/abstracts/search?q=Massimo%20Gennaretti"> Massimo Gennaretti</a>, <a href="https://publications.waset.org/abstracts/search?q=Stefano%20Panzieri"> Stefano Panzieri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents a nonlinear differential model, for a three-bladed horizontal axis wind turbine (HAWT) suited for control applications. It is based on a 8-dofs, lumped parameters structural dynamics coupled with a quasi-steady sectional aerodynamics. In particular, using the Euler-Lagrange Equation (Energetic Variation approach), the authors derive, and successively validate, such model. For the derivation of the aerodynamic model, the Greenbergs theory, an extension of the theory proposed by Theodorsen to the case of thin airfoils undergoing pulsating flows, is used. Specifically, in this work, the authors restricted that theory under the hypothesis of low perturbation reduced frequency k, which causes the lift deficiency function C(k) to be real and equal to 1. Furthermore, the expressions of the aerodynamic loads are obtained using the quasi-steady strip theory (Hodges and Ormiston), as a function of the chordwise and normal components of relative velocity between flow and airfoil Ut, Up, their derivatives, and section angular velocity ε˙. For the validation of the proposed model, the authors carried out open and closed-loop simulations of a 5 MW HAWT, characterized by radius R =61.5 m and by mean chord c = 3 m, with a nominal angular velocity Ωn = 1.266rad/sec. The first analysis performed is the steady state solution, where a uniform wind Vw = 11.4 m/s is considered and a collective pitch angle θ = 0.88◦ is imposed. During this step, the authors noticed that the proposed model is intrinsically periodic due to the effect of the wind and of the gravitational force. In order to reject this periodic trend in the model dynamics, the authors propose a collective repetitive control algorithm coupled with a PD controller. In particular, when the reference command to be tracked and/or the disturbance to be rejected are periodic signals with a fixed period, the repetitive control strategies can be applied due to their high precision, simple implementation and little performance dependency on system parameters. The functional scheme of a repetitive controller is quite simple and, given a periodic reference command, is composed of a control block Crc(s) usually added to an existing feedback control system. The control block contains and a free time-delay system eτs in a positive feedback loop, and a low-pass filter q(s). It should be noticed that, while the time delay term reduces the stability margin, on the other hand the low pass filter is added to ensure stability. It is worth noting that, in this work, the authors propose a phase shifting for the controller and the delay system has been modified as e^(−(T−γk)), where T is the period of the signal and γk is a phase shifting of k samples of the same periodic signal. It should be noticed that, the phase shifting technique is particularly useful in non-minimum phase systems, such as flexible structures. In fact, using the phase shifting, the iterative algorithm could reach the convergence also at high frequencies. Notice that, in our case study, the shifting of k samples depends both on the rotor angular velocity Ω and on the rotor azimuth angle Ψ: we refer to this controller as a spatial repetitive controller. The collective repetitive controller has also been coupled with a C(s) = PD(s), in order to dampen oscillations of the blades. The performance of the spatial repetitive controller is compared with an industrial PI controller. In particular, starting from wind speed velocity Vw = 11.4 m/s the controller is asked to maintain the nominal angular velocity Ωn = 1.266rad/s after an instantaneous increase of wind speed (Vw = 15 m/s). Then, a purely periodic external disturbance is introduced in order to stress the capabilities of the repetitive controller. The results of the simulations show that, contrary to a simple PI controller, the spatial repetitive-PD controller has the capability to reject both external disturbances and periodic trend in the model dynamics. Finally, the nominal value of the angular velocity is reached, in accordance with results obtained with commercial software for a turbine of the same type. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=wind%20turbines" title="wind turbines">wind turbines</a>, <a href="https://publications.waset.org/abstracts/search?q=aeroelasticity" title=" aeroelasticity"> aeroelasticity</a>, <a href="https://publications.waset.org/abstracts/search?q=repetitive%20control" title=" repetitive control"> repetitive control</a>, <a href="https://publications.waset.org/abstracts/search?q=periodic%20systems" title=" periodic systems"> periodic systems</a> </p> <a href="https://publications.waset.org/abstracts/55810/a-spatial-repetitive-controller-applied-to-an-aeroelastic-model-for-wind-turbines" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55810.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">249</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Mapping Thermal Properties Using Resistivity, Lithology and Thermal Conductivity Measurements</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Pasquali">Riccardo Pasquali</a>, <a href="https://publications.waset.org/abstracts/search?q=Keith%20Harlin"> Keith Harlin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mark%20Muller"> Mark Muller</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ShallowTherm project is focussed on developing and applying a methodology for extrapolating relatively sparsely sampled thermal conductivity measurements across Ireland using mapped Litho-Electrical (LE) units. The primary data used consist of electrical resistivities derived from the Geological Survey Ireland Tellus airborne electromagnetic dataset, GIS-based maps of Irish geology, and rock thermal conductivities derived from both the current Irish Ground Thermal Properties (IGTP) database and a new programme of sampling and laboratory measurement. The workflow has been developed across three case-study areas that sample a range of different calcareous, arenaceous, argillaceous, and volcanic lithologies. Statistical analysis of resistivity data from individual geological formations has been assessed and integrated with detailed lithological descriptions to define distinct LE units. Thermal conductivity measurements from core and hand samples have been acquired for every geological formation within each study area. The variability and consistency of thermal conductivity measurements within each LE unit is examined with the aim of defining a characteristic thermal conductivity (or range of thermal conductivities) for each LE unit. Mapping of LE units, coupled with characteristic thermal conductivities, provides a method of defining thermal conductivity properties at a regional scale and facilitating the design of ground source heat pump closed-loop collectors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=thermal%20conductivity" title="thermal conductivity">thermal conductivity</a>, <a href="https://publications.waset.org/abstracts/search?q=ground%20source%20heat%20pumps" title=" ground source heat pumps"> ground source heat pumps</a>, <a href="https://publications.waset.org/abstracts/search?q=resistivity" title=" resistivity"> resistivity</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20exchange" title=" heat exchange"> heat exchange</a>, <a href="https://publications.waset.org/abstracts/search?q=shallow%20geothermal" title=" shallow geothermal"> shallow geothermal</a>, <a href="https://publications.waset.org/abstracts/search?q=Ireland" title=" Ireland"> Ireland</a> </p> <a href="https://publications.waset.org/abstracts/130116/mapping-thermal-properties-using-resistivity-lithology-and-thermal-conductivity-measurements" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/130116.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">181</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Theatrical Architecture in Bologna at the Beginning of the Twentieth Century: The Renaissance of Modernissimo Cinema</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Giorgia%20Predari">Giorgia Predari</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Gulli"> Riccardo Gulli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper describes the history and the stylistic choices adopted in the construction of Palazzo Ronzani in Bologna, which was the first building to rise after the heavy demolitions carried out in the historical center of the city at the beginning of the twentieth century. In 1910, the local administration adopted a detailed plan to change the aspect of the city, as it was already happening in the main European capitals. In this context, starting from 1911, the architect and scenographer Gualtiero Pontoni designed for Alessandro Ronzani -the owner of a well-known Bolognese beer company- his Palazzo, which is listed among the first multifunctional buildings in Bologna, containing offices, commercial activities, and entertainment spaces. In an area of about 2000 m², the architect was able to propose a theatre with a capacity of 2000 seats at the basement, shops, a cafè-chantant and a restaurant on the ground floor, clubs, studios and commercial stores on the mezzanine and the first plan, and a hotel on the upper floors. The whole core of the building, at the underground levels, consisted of a reinforced concrete frame (one of the first examples of this type of construction in the city), which allowed the hall to have a free span of 11 x 12 meters, and a height of about 9 meters. Used until 2007 as a cinema, the hall has remained then in disuse for almost 10 years, but now an important functional restoration project with a strong architectural and scenographic value is taking place. It will bring the spaces back to the original geometries, in a historical and artistic condition inspired by the styles of the early Twentieth century. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Modernissimo" title="Modernissimo">Modernissimo</a>, <a href="https://publications.waset.org/abstracts/search?q=Palazzo%20Ronzani" title=" Palazzo Ronzani"> Palazzo Ronzani</a>, <a href="https://publications.waset.org/abstracts/search?q=liberty" title=" liberty"> liberty</a>, <a href="https://publications.waset.org/abstracts/search?q=Bologna" title=" Bologna"> Bologna</a> </p> <a href="https://publications.waset.org/abstracts/109407/theatrical-architecture-in-bologna-at-the-beginning-of-the-twentieth-century-the-renaissance-of-modernissimo-cinema" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/109407.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Food Supplements and Natural Products to Slow Down Biological Aging</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Coppa%20Federica">Coppa Federica</a>, <a href="https://publications.waset.org/abstracts/search?q=Iannello%20Giulia"> Iannello Giulia</a>, <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20Stefania"> Pennisi Stefania</a>, <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20Graziella"> Giuffrida Graziella</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20Riccardo"> Lo Faro Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20Simone"> Cartelli Simone</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20Greta"> Ferruggia Greta</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20Maria%20Violetta"> Brundo Maria Violetta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, a new field of basic research has emerged: the biology and physiology of extracellular vesicles and their application in diagnostics and therapy. In particular, exosomes attract the scientific community as nanovesicles of endosomal origin, which can be secreted by a variety of cells and are found in all biological fluids. Exosomes have recently gained attention also in the cosmetic field: in fact, they are used in creams, serums and masks for topical use, proving to have a series of therapeutic and anti-aging benefits. To date, the oral administration of exosomes is the subject of attention because it represents a non-invasive and efficient method for delivering bioactive molecules into the intestine. We decided to focus our research on the creation of a food supplement that contains various bioactive factors, vitamins, and a new technology called AMPLEX PLUS, containing a mixture of 20 different biologically active factors (GF20) and exosomes isolated and purified from bovine colostrum. We have demonstrated in vitro that this new supplement acts on telomerase, slowing down cell aging. Amplex plus increased the proliferation rate of cells and the addition of it reduced the rate of telomere shortening. Under oxidative stress conditions (H2O2 – induced), the TSR increased; however, treatment with colostrum appeared to attenuate this increase. In particular, after 2 weeks of treatment, AMPLEX plus increased the proliferation rate of cells and exerted a protective effect on telomere length erosion, reducing the rate of its shortening. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AMPLEX%20PLUS" title="AMPLEX PLUS">AMPLEX PLUS</a>, <a href="https://publications.waset.org/abstracts/search?q=colostrum" title=" colostrum"> colostrum</a>, <a href="https://publications.waset.org/abstracts/search?q=exosomes" title=" exosomes"> exosomes</a>, <a href="https://publications.waset.org/abstracts/search?q=telomerase" title=" telomerase"> telomerase</a> </p> <a href="https://publications.waset.org/abstracts/187383/food-supplements-and-natural-products-to-slow-down-biological-aging" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187383.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">52</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Evaluation of Short-Term Load Forecasting Techniques Applied for Smart Micro-Grids</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Xiaolei%20Hu">Xiaolei Hu</a>, <a href="https://publications.waset.org/abstracts/search?q=Enrico%20Ferrera"> Enrico Ferrera</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Tomasi"> Riccardo Tomasi</a>, <a href="https://publications.waset.org/abstracts/search?q=Claudio%20Pastrone"> Claudio Pastrone</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Load Forecasting plays a key role in making today's and future's Smart Energy Grids sustainable and reliable. Accurate power consumption prediction allows utilities to organize in advance their resources or to execute Demand Response strategies more effectively, which enables several features such as higher sustainability, better quality of service, and affordable electricity tariffs. It is easy yet effective to apply Load Forecasting at larger geographic scale, i.e. Smart Micro Grids, wherein the lower available grid flexibility makes accurate prediction more critical in Demand Response applications. This paper analyses the application of short-term load forecasting in a concrete scenario, proposed within the EU-funded GreenCom project, which collect load data from single loads and households belonging to a Smart Micro Grid. Three short-term load forecasting techniques, i.e. linear regression, artificial neural networks, and radial basis function network, are considered, compared, and evaluated through absolute forecast errors and training time. The influence of weather conditions in Load Forecasting is also evaluated. A new definition of Gain is introduced in this paper, which innovatively serves as an indicator of short-term prediction capabilities of time spam consistency. Two models, 24- and 1-hour-ahead forecasting, are built to comprehensively compare these three techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=short-term%20load%20forecasting" title="short-term load forecasting">short-term load forecasting</a>, <a href="https://publications.waset.org/abstracts/search?q=smart%20micro%20grid" title=" smart micro grid"> smart micro grid</a>, <a href="https://publications.waset.org/abstracts/search?q=linear%20regression" title=" linear regression"> linear regression</a>, <a href="https://publications.waset.org/abstracts/search?q=artificial%20neural%20networks" title=" artificial neural networks"> artificial neural networks</a>, <a href="https://publications.waset.org/abstracts/search?q=radial%20basis%20function%20network" title=" radial basis function network"> radial basis function network</a>, <a href="https://publications.waset.org/abstracts/search?q=gain" title=" gain"> gain</a> </p> <a href="https://publications.waset.org/abstracts/19621/evaluation-of-short-term-load-forecasting-techniques-applied-for-smart-micro-grids" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19621.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">468</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Electrochemotherapy of Portal Vein Tumor Thrombus as Dowstaging to Liver Transplantation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Luciano%20Tarantino">Luciano Tarantino</a>, <a href="https://publications.waset.org/abstracts/search?q=Emanuele%20Balzano"> Emanuele Balzano</a>, <a href="https://publications.waset.org/abstracts/search?q=Paolo%20Tarantino"> Paolo Tarantino</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Aurelio%20Nasto"> Riccardo Aurelio Nasto</a>, <a href="https://publications.waset.org/abstracts/search?q=Aurelio%20Nasto"> Aurelio Nasto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Liver transplantation (OLT) is contraindicate in Portal Vein tumor Thrombosis (PVTT) from Hepatocellular Carcinoma at hepatic hilum(pH-HCC) Surgery,Thermal ablation and chemotherapy show poorer outcomes Electrochemotherapy (ECT) has been successfully used in patients with pH-HCC with PVTT. We report the results of ECT as downstaging aimed to definitive cure by OLT. F.P. 53 years HBV related Cirrhosis Child-Pugh B7 class; EGDS F2 aesophageal Varices. Diabetes. April 2016 : Enhanced Computed Tomography (CT) detected HCC(n.3 nodules in VII-VIII-VI;diameter range=25 cm) and PVTT of right portal vein. The patient was considered ineligible for OLT. May 2016: first ablation session with percutaneous Radiofrequency-ablation(RFA) of 3 HCC-nodules . August 2016: second ablation session with ECT of PVTT. CT october 2016: disappearance of PVTT and patent right portal vein. No intraparenchymal recurrence. CT march 2017: No recurrence in portal vein and in the left lobe. local recurrence in the VII-VIII segments. May 2017 : transarterial chemoembolization (TACE) of right lobe recurrences. CT October 2017: patent right portal vein. No recurrence. The patient was reconsidered for OLT. He underwent OLT in April 2018. At 36-months follow-up , no intrahepatic recurrence of HCC occurred. March 2021: enhanced CT and PET/CT detected a single small nodule (1.5 cm) uptaking tracer in the left upper pulmonary lobe, no hepatic recurrence . CT-guided FNB showed metastasis from HCC . June 2021: left lung upper lobectomy . At the current time the patient is alive and recurrence-free at 64 months follow-up. ECT Could be aneffective technique as pre-OLT dowstaging in HCC with PVTT. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=liver%20tumor%20ablation" title="liver tumor ablation">liver tumor ablation</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20ultrasound" title=" interventional ultrasound"> interventional ultrasound</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemotherapy" title=" electrochemotherapy"> electrochemotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20transplantation" title=" liver transplantation"> liver transplantation</a> </p> <a href="https://publications.waset.org/abstracts/172793/electrochemotherapy-of-portal-vein-tumor-thrombus-as-dowstaging-to-liver-transplantation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172793.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">118</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> A Benchtop Experiment to Study Changes in Tracer Distribution in the Subarachnoid Space</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Smruti%20Mahapatra">Smruti Mahapatra</a>, <a href="https://publications.waset.org/abstracts/search?q=Dipankar%20Biswas"> Dipankar Biswas</a>, <a href="https://publications.waset.org/abstracts/search?q=Richard%20Um"> Richard Um</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Meggyesy"> Michael Meggyesy</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Serra"> Riccardo Serra</a>, <a href="https://publications.waset.org/abstracts/search?q=Noah%20Gorelick"> Noah Gorelick</a>, <a href="https://publications.waset.org/abstracts/search?q=Steven%20Marra"> Steven Marra</a>, <a href="https://publications.waset.org/abstracts/search?q=Amir%20Manbachi"> Amir Manbachi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mark%20G.%20Luciano"> Mark G. Luciano</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Intracranial pressure (ICP) is profoundly regulated by the effects of cardiac pulsation and the volume of the incoming blood. Furthermore, these effects on ICP are incremented by the presence of a rigid skull that does not allow for changes in total volume during the cardiac cycle. These factors play a pivotal role in cerebrospinal fluid (CSF) dynamics and distribution, with consequences that are not well understood to this date and that may have a deep effect on the Central Nervous System (CNS) functioning. We designed this study with two specific aims: (a) To study how pulsatility influences local CSF flow, and (b) To study how modulating intracranial pressure affects drug distribution throughout the SAS globally. In order to achieve these aims, we built an elaborate in-vitro model of the SAS closely mimicking the dimensions and flow rates of physiological systems. To modulate intracranial pressure, we used an intracranially implanted, cardiac-gated, volume-oscillating balloon (CADENCE device). Commercially available dye was used to visualize changes in CSF flow. We first implemented two control cases, seeing how the tracer behaves in the presence of pulsations from the brain phantom and the balloon individually. After establishing the controls, we tested 2 cases, having the brain and the balloon pulsate together in sync and out of sync. We then analyzed the distribution area using image processing software. The in-sync case produced a significant increase, 5x times, in the tracer distribution area relative to the out-of-sync case. Assuming that the tracer fluid would mimic blood flow movement, a drug introduced in the SAS with such a system in place would enhance drug distribution and increase the bioavailability of therapeutic drugs to a wider spectrum of brain tissue. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blood-brain%20barrier" title="blood-brain barrier">blood-brain barrier</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac-gated" title=" cardiac-gated"> cardiac-gated</a>, <a href="https://publications.waset.org/abstracts/search?q=cerebrospinal%20fluid" title=" cerebrospinal fluid"> cerebrospinal fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery" title=" drug delivery"> drug delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=neurosurgery" title=" neurosurgery"> neurosurgery</a> </p> <a href="https://publications.waset.org/abstracts/139079/a-benchtop-experiment-to-study-changes-in-tracer-distribution-in-the-subarachnoid-space" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/139079.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">183</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> An Inventory Management Model to Manage the Stock Level for Irregular Demand Items</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Patriarca">Riccardo Patriarca</a>, <a href="https://publications.waset.org/abstracts/search?q=Giulio%20Di%20Gravio"> Giulio Di Gravio</a>, <a href="https://publications.waset.org/abstracts/search?q=Francesco%20Costantino"> Francesco Costantino</a>, <a href="https://publications.waset.org/abstracts/search?q=Massimo%20Tronci"> Massimo Tronci</a> </p> <p class="card-text"><strong>Abstract:</strong></p> An accurate inventory management policy acquires a crucial role in the several high-availability sectors. In these sectors, due to the high-cost of spares and backorders, an (S-1, S) replenishment policy is necessary for high-availability items. The policy enables the shipment of a substitute efficient item anytime the inventory size decreases by one. This policy can be modelled following the Multi-Echelon Technique for Recoverable Item Control (METRIC). The METRIC is a system-based technique that allows defining the optimum stock level in a multi-echelon network, adopting measures in line with the decision-maker’s perspective. The METRIC defines an availability-cost function with inventory costs and required service levels, using as inputs data about the demand trend, the supplying and maintenance characteristics of the network and the budget/availability constraints. The traditional METRIC relies on the hypothesis that a Poisson distribution well represents the demand distribution in case of items with a low failure rate. However, in this research, we will explore the effects of using a Poisson distribution to model the demand of low failure rate items characterized by an irregular demand trend. This characteristic of a demand is not included in the traditional METRIC formulation leading to the need of revising its traditional formulation. Using the CV (Coefficient of Variation) and ADI (Average inter-Demand Interval) classification, we will define the inherent flaws of Poisson-based METRIC for irregular demand items, defining an innovative ad hoc distribution which can better fit the irregular demands. This distribution will allow defining proper stock levels to reduce stocking and backorder costs due to the high irregularities in the demand trend. A case study in the aviation domain will clarify the benefits of this innovative METRIC approach. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=METRIC" title="METRIC">METRIC</a>, <a href="https://publications.waset.org/abstracts/search?q=inventory%20management" title=" inventory management"> inventory management</a>, <a href="https://publications.waset.org/abstracts/search?q=irregular%20demand" title=" irregular demand"> irregular demand</a>, <a href="https://publications.waset.org/abstracts/search?q=spare%20parts" title=" spare parts"> spare parts</a> </p> <a href="https://publications.waset.org/abstracts/73000/an-inventory-management-model-to-manage-the-stock-level-for-irregular-demand-items" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/73000.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">347</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Evidence of Microplastics Ingestion in Two Commercial Cephalopod Species: Octopus Vulgaris and Sepia Officinalis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Federica%20Laface">Federica Laface</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristina%20Ped%C3%A0"> Cristina Pedà</a>, <a href="https://publications.waset.org/abstracts/search?q=Francesco%20Longo"> Francesco Longo</a>, <a href="https://publications.waset.org/abstracts/search?q=Francesca%20de%20Domenico"> Francesca de Domenico</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Minichino"> Riccardo Minichino</a>, <a href="https://publications.waset.org/abstracts/search?q=Pierpaolo%20Consoli"> Pierpaolo Consoli</a>, <a href="https://publications.waset.org/abstracts/search?q=Pietro%20Battaglia"> Pietro Battaglia</a>, <a href="https://publications.waset.org/abstracts/search?q=Silvestro%20Greco"> Silvestro Greco</a>, <a href="https://publications.waset.org/abstracts/search?q=Teresa%20Romeo"> Teresa Romeo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Plastics pollution represents one of the most important threats to marine biodiversity. In the last decades, different species are investigated to evaluate the extent of the plastic ingestion phenomenon. Even if the cephalopods play an important role in the food chain, they are still poorly studied. The aim of this research was to investigate the plastic ingestion in two commercial cephalopod species from the southern Tyrrhenian Sea: the common octopus, Octopus vulgaris (n=6; mean mantle length ML 10.7 ± 1.8) and the common cuttlefish, Sepia officinalis (n=13; mean ML 13.2 ± 1.7). Plastics were extracted from the filters obtained by the chemical digestion of cephalopods gastrointestinal tracts (GITs), using 10% potassium hydroxide (KOH) solution in a 1:5 (w/v) ratio. Once isolated, particles were photographed, measured, and their size class, shape and color were recorded. A total of 81 items was isolated from 16 of the 19 examined GITs, representing a total occurrence (%O) of 84.2% with a mean value of 4.3 ± 8.6 particles per individual. In particular, 62 plastics were found in 6 specimens of O. vulgaris (%O=100) and 19 particles in 10 S. officinalis (%O=94.7). In both species, the microplastics size class was the most abundant (93.8%). Plastic items found in O. vulgaris were mainly fibers (61%) while fragments were the most frequent in S. officinalis (53%). Transparent was the most common color in both species. The analysis will be completed by Fourier transform infrared (FT-IR) spectroscopy technique in order to identify polymers nature. This study reports preliminary data on plastic ingestion events in two cephalopods species and represents the first record of plastic ingestion by the common octopus. Microplastic items detected in both common octopus and common cuttlefish could derive from secondary and/or accidental ingestion events, probably due to their behavior, feeding habits and anatomical features. Further studies will be required to assess the effect of marine litter pollution in these ecologically and commercially important species. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cephalopods" title="cephalopods">cephalopods</a>, <a href="https://publications.waset.org/abstracts/search?q=GIT%20analysis" title=" GIT analysis"> GIT analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=marine%20pollution" title=" marine pollution"> marine pollution</a>, <a href="https://publications.waset.org/abstracts/search?q=Mediterranean%20sea" title=" Mediterranean sea"> Mediterranean sea</a>, <a href="https://publications.waset.org/abstracts/search?q=microplastics" title=" microplastics"> microplastics</a> </p> <a href="https://publications.waset.org/abstracts/140632/evidence-of-microplastics-ingestion-in-two-commercial-cephalopod-species-octopus-vulgaris-and-sepia-officinalis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140632.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">254</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Environmental Conditions Simulation Device for Evaluating Fungal Growth on Wooden Surfaces</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Cacciotti">Riccardo Cacciotti</a>, <a href="https://publications.waset.org/abstracts/search?q=Jiri%20Frankl"> Jiri Frankl</a>, <a href="https://publications.waset.org/abstracts/search?q=Benjamin%20Wolf"> Benjamin Wolf</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20%20Machacek"> Michael Machacek</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Moisture fluctuations govern the occurrence of fungi-related problems in buildings, which may impose significant health risks for users and even lead to structural failures. Several numerical engineering models attempt to capture the complexity of mold growth on building materials. From real life observations, in cases with suppressed daily variations of boundary conditions, e.g. in crawlspaces, mold growth model predictions well correspond with the observed mold growth. On the other hand, in cases with substantial diurnal variations of boundary conditions, e.g. in the ventilated cavity of a cold flat roof, mold growth predicted by the models is significantly overestimated. This study, founded by the Grant Agency of the Czech Republic (GAČR 20-12941S), aims at gaining a better understanding of mold growth behavior on solid wood, under varying boundary conditions. In particular, the experimental investigation focuses on the response of mold to changing conditions in the boundary layer and its influence on heat and moisture transfer across the surface. The main results include the design and construction at the facilities of ITAM (Prague, Czech Republic) of an innovative device allowing for the simulation of changing environmental conditions in buildings. It consists of a square section closed circuit with rough dimensions 200 × 180 cm and cross section roughly 30 × 30 cm. The circuit is thermally insulated and equipped with an electric fan to control air flow inside the tunnel, a heat and humidity exchange unit to control the internal RH and variations in temperature. Several measuring points, including an anemometer, temperature and humidity sensor, a loading cell in the test section for recording mass changes, are provided to monitor the variations of parameters during the experiments. The research is ongoing and it is expected to provide the final results of the experimental investigation at the end of 2022. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=moisture" title="moisture">moisture</a>, <a href="https://publications.waset.org/abstracts/search?q=mold%20growth" title=" mold growth"> mold growth</a>, <a href="https://publications.waset.org/abstracts/search?q=testing" title=" testing"> testing</a>, <a href="https://publications.waset.org/abstracts/search?q=wood" title=" wood"> wood</a> </p> <a href="https://publications.waset.org/abstracts/137297/environmental-conditions-simulation-device-for-evaluating-fungal-growth-on-wooden-surfaces" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137297.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">133</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Monte Carlo and Biophysics Analysis in a Criminal Trial</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Luca%20Indovina">Luca Indovina</a>, <a href="https://publications.waset.org/abstracts/search?q=Carmela%20Coppola"> Carmela Coppola</a>, <a href="https://publications.waset.org/abstracts/search?q=Carlo%20Altucci"> Carlo Altucci</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Barberi"> Riccardo Barberi</a>, <a href="https://publications.waset.org/abstracts/search?q=Rocco%20Romano"> Rocco Romano</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper a real court case, held in Italy at the Court of Nola, in which a correct physical description, conducted with both a Monte Carlo and biophysical analysis, would have been sufficient to arrive at conclusions confirmed by documentary evidence, is considered. This will be an example of how forensic physics can be useful in confirming documentary evidence in order to reach hardly questionable conclusions. This was a libel trial in which the defendant, Mr. DS (Defendant for Slander), had falsely accused one of his neighbors, Mr. OP (Offended Person), of having caused him some damages. The damages would have been caused by an external plaster piece that would have detached from the neighbor&rsquo;s property and would have hit Mr DS while he was in his garden, much more than a meter far away from the facade of the building from which the plaster piece would have detached. In the trial, Mr. DS claimed to have suffered a scratch on his forehead, but he never showed the plaster that had hit him, nor was able to tell from where the plaster would have arrived. Furthermore, Mr. DS presented a medical certificate with a diagnosis of contusion of the cerebral cortex. On the contrary, the images of Mr. OP&rsquo;s security cameras do not show any movement in the garden of Mr. DS in a long interval of time (about 2 hours) around the time of the alleged accident, nor do they show any people entering or coming out from the house of Mr. DS in the same interval of time. Biophysical analysis shows that both the diagnosis of the medical certificate and the wound declared by the defendant, already in conflict with each other, are not compatible with the fall of external plaster pieces too small to be found. The wind was at a level 1 of the Beaufort scale, that is, unable to raise even dust (level 4 of the Beaufort scale). Therefore, the motion of the plaster pieces can be described as a projectile motion, whereas collisions with the building cornice can be treated using Newtons law of coefficients of restitution. Numerous numerical Monte Carlo simulations show that the pieces of plaster would not have been able to reach even the garden of Mr. DS, let alone a distance over 1.30 meters. Results agree with the documentary evidence (images of Mr. OP&rsquo;s security cameras) that Mr. DS could not have been hit by plaster pieces coming from Mr. OP&rsquo;s property. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biophysics%20analysis" title="biophysics analysis">biophysics analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=Monte%20Carlo%20simulations" title=" Monte Carlo simulations"> Monte Carlo simulations</a>, <a href="https://publications.waset.org/abstracts/search?q=Newton%E2%80%99s%20law%20of%20restitution" title=" Newton’s law of restitution"> Newton’s law of restitution</a>, <a href="https://publications.waset.org/abstracts/search?q=projectile%20motion" title=" projectile motion"> projectile motion</a> </p> <a href="https://publications.waset.org/abstracts/130139/monte-carlo-and-biophysics-analysis-in-a-criminal-trial" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/130139.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">130</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> CSPG4 Molecular Target in Canine Melanoma, Osteosarcoma and Mammary Tumors for Novel Therapeutic Strategies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Paola%20Modesto">Paola Modesto</a>, <a href="https://publications.waset.org/abstracts/search?q=Floriana%20Fruscione"> Floriana Fruscione</a>, <a href="https://publications.waset.org/abstracts/search?q=Isabella%20Martini"> Isabella Martini</a>, <a href="https://publications.waset.org/abstracts/search?q=Simona%20Perga"> Simona Perga</a>, <a href="https://publications.waset.org/abstracts/search?q=Federica%20Riccardo"> Federica Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariateresa%20Camerino"> Mariateresa Camerino</a>, <a href="https://publications.waset.org/abstracts/search?q=Davide%20Giacobino"> Davide Giacobino</a>, <a href="https://publications.waset.org/abstracts/search?q=Cecilia%20Gola"> Cecilia Gola</a>, <a href="https://publications.waset.org/abstracts/search?q=Luca%20Licenziato"> Luca Licenziato</a>, <a href="https://publications.waset.org/abstracts/search?q=Elisabetta%20Razzuoli"> Elisabetta Razzuoli</a>, <a href="https://publications.waset.org/abstracts/search?q=Katia%20Varello"> Katia Varello</a>, <a href="https://publications.waset.org/abstracts/search?q=Lorella%20Maniscalco"> Lorella Maniscalco</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20Bozzetta"> Elena Bozzetta</a>, <a href="https://publications.waset.org/abstracts/search?q=Angelo%20Ferrari"> Angelo Ferrari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Canine and human melanoma, osteosarcoma (OSA), and mammary carcinomas are aggressive tumors with common characteristics making dogs a good model for comparative oncology. Novel therapeutic strategies against these tumors could be useful to both species. In humans, chondroitin sulphate proteoglycan 4 (CSPG4) is a marker involved in tumor progression and could be a candidate target for immunotherapy. The anti-CSPG4 DNA electrovaccination has shown to be an effective approach for canine malignant melanoma (CMM) [1]. An immunohistochemistry evaluation of CSPG4 expression in tumour tissue is generally performed prior to electrovaccination. To assess the possibility to perform a rapid molecular evaluation and in order to validate these spontaneous canine tumors as the model for human studies, we investigate the CSPG4 gene expression by RT qPCR in CMM, OSA, and canine mammary tumors (CMT). The total RNA was extracted from RNAlater stored tissue samples (CMM n=16; OSA n=13; CMT n=6; five paired normal tissues for CMM, five paired normal tissues for OSA and one paired normal tissue for CMT), retro-transcribed and then analyzed by duplex RT-qPCR using two different TaqMan assays for the target gene CSPG4 and the internal reference gene (RG) Ribosomal Protein S19 (RPS19). RPS19 was selected from a panel of 9 candidate RGs, according to NormFinder analysis following the protocol already described [2]. Relative expression was analyzed by CFX Maestro™ Software. Student t-test and ANOVA were performed (significance set at P<0.05). Results showed that gene expression of CSPG4 in OSA tissues is significantly increased by 3-4 folds when compared to controls. In CMT, gene expression of the target was increased from 1.5 to 19.9 folds. In melanoma, although an increasing trend was observed, no significant differences between the two groups were highlighted. Immunohistochemistry analysis of the two cancer types showed that the expression of CSPG4 within CMM is concentrated in isles of cells compared to OSA, where the distribution of positive cells is homogeneous. This evidence could explain the differences in gene expression results.CSPG4 immunohistochemistry evaluation in mammary carcinoma is in progress. The evidence of CSPG4 expression in a different type of canine tumors opens the way to the possibility of extending the CSPG4 immunotherapy marker in CMM, OSA, and CMT and may have an impact to translate this strategy modality to human oncology. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=canine%20melanoma" title="canine melanoma">canine melanoma</a>, <a href="https://publications.waset.org/abstracts/search?q=canine%20mammary%20carcinomas" title=" canine mammary carcinomas"> canine mammary carcinomas</a>, <a href="https://publications.waset.org/abstracts/search?q=canine%20osteosarcoma" title=" canine osteosarcoma"> canine osteosarcoma</a>, <a href="https://publications.waset.org/abstracts/search?q=CSPG4" title=" CSPG4"> CSPG4</a>, <a href="https://publications.waset.org/abstracts/search?q=gene%20expression" title=" gene expression"> gene expression</a>, <a href="https://publications.waset.org/abstracts/search?q=immunotherapy" title=" immunotherapy"> immunotherapy</a> </p> <a href="https://publications.waset.org/abstracts/141925/cspg4-molecular-target-in-canine-melanoma-osteosarcoma-and-mammary-tumors-for-novel-therapeutic-strategies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141925.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">174</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Therapy Finding and Perspectives on Limbic Resonance in Gifted Adults</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andreas%20Aceranti">Andreas Aceranti</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Dossena"> Riccardo Dossena</a>, <a href="https://publications.waset.org/abstracts/search?q=Marco%20Colorato"> Marco Colorato</a>, <a href="https://publications.waset.org/abstracts/search?q=Simonetta%20Vernocchi"> Simonetta Vernocchi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> By the term “limbic resonance,” we usually refer to a state of deep connection, both emotional and physiological, between people who, when in resonance, find their limbic systems in tune with one another. Limbic resonance is not only about sharing emotions but also physiological states. In fact, people in such resonance can influence each other’s heart rate, blood pressure, and breathing. Limbic resonance is fundamental for human beings to connect and create deep bonds among a certain group. It is fundamental for our social skills. A relationship between gifted and resonant subjects is perceived as feeling safe, living the relation like an isle of serenity where it is possible to recharge, to communicate without words, to understand each others without giving explanations, to strengthen the balance of each member of the group. Within the circle, self-esteem is consolidated and makes it stronger to face what is outside, others, and reality. The idea that gifted people who are together may be unfit for the world does not correspond to the truth. The circle made up of people with high cognitive potential characterized by a limbic resonance is, in general, experienced as a solid platform from which you can safely move away and where you can return to recover strength. We studied 8 adults (between 21 and 47 years old). All of them with IQ higher than 130. We monitored their brain waves frequency (alpha, beta, theta, gamma, delta) by means of biosensing tracker along with their physiological states (heart beat frequency, blood pressure, breathing frequency, pO2, pCO2) and some blood works only (5-HT, dopamine, catecholamines, cortisol). The subjects of the study were asked to adhere to a protocol involving bonding activities (such as team building activities), role plays, meditation sessions, and group therapy. All these activities were carried out together. We observed that after about 4 months of activities, their brain waves frequencies tended to tune quicker and quicker. After 9 months, the bond among them was so important that they could “sense” each other inner states and sometimes also guess each others’ thoughts. According to our findings, it may be hypothesized that large synchronized outbursts of cortex neurons produces not only brain waves but also electromagnetic fields that may be able to influence the cortical neurons’ activity of other people’s brain by inducing action potentials in large groups of neurons and this is reasonably conceivable to be able to transmit information such as different emotions and cognition cues to the other’s brain. We also believe that upcoming research should focus on clarifying the role of brain magnetic particles in brain-to-brain communication. We also believe that further investigations should be carried out on the presence and role of cryptochromes to evaluate their potential roles in direct brain-to-brain communication. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=limbic%20resonance" title="limbic resonance">limbic resonance</a>, <a href="https://publications.waset.org/abstracts/search?q=psychotherapy" title=" psychotherapy"> psychotherapy</a>, <a href="https://publications.waset.org/abstracts/search?q=brain%20waves" title=" brain waves"> brain waves</a>, <a href="https://publications.waset.org/abstracts/search?q=emotion%20regulation" title=" emotion regulation"> emotion regulation</a>, <a href="https://publications.waset.org/abstracts/search?q=giftedness" title=" giftedness"> giftedness</a> </p> <a href="https://publications.waset.org/abstracts/159196/therapy-finding-and-perspectives-on-limbic-resonance-in-gifted-adults" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159196.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">92</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Analysis of Differentially Expressed Genes in Spontaneously Occurring Canine Melanoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Simona%20Perga">Simona Perga</a>, <a href="https://publications.waset.org/abstracts/search?q=Chiara%20Beltramo"> Chiara Beltramo</a>, <a href="https://publications.waset.org/abstracts/search?q=Floriana%20Fruscione"> Floriana Fruscione</a>, <a href="https://publications.waset.org/abstracts/search?q=Isabella%20Martini"> Isabella Martini</a>, <a href="https://publications.waset.org/abstracts/search?q=Federica%20Cavallo"> Federica Cavallo</a>, <a href="https://publications.waset.org/abstracts/search?q=Federica%20Riccardo"> Federica Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Paolo%20Buracco"> Paolo Buracco</a>, <a href="https://publications.waset.org/abstracts/search?q=Selina%20Iussich"> Selina Iussich</a>, <a href="https://publications.waset.org/abstracts/search?q=Elisabetta%20Razzuoli"> Elisabetta Razzuoli</a>, <a href="https://publications.waset.org/abstracts/search?q=Katia%20Varello"> Katia Varello</a>, <a href="https://publications.waset.org/abstracts/search?q=Lorella%20Maniscalco"> Lorella Maniscalco</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20Bozzetta"> Elena Bozzetta</a>, <a href="https://publications.waset.org/abstracts/search?q=Angelo%20Ferrari"> Angelo Ferrari</a>, <a href="https://publications.waset.org/abstracts/search?q=Paola%20Modesto"> Paola Modesto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Human and canine melanoma have common clinical, histologic characteristics making dogs a good model for comparative oncology. The identification of specific genes and a better understanding of the genetic landscape, signaling pathways, and tumor–microenvironmental interactions involved in the cancer onset and progression is essential for the development of therapeutic strategies against this tumor in both species. In the present study, the differential expression of genes in spontaneously occurring canine melanoma and in paired normal tissue was investigated by targeted RNAseq. Material and Methods: Total RNA was extracted from 17 canine malignant melanoma (CMM) samples and from five paired normal tissues stored in RNA-later. In order to capture the greater genetic variability, gene expression analysis was carried out using two panels (Qiagen): Human Immuno-Oncology (HIO) and Mouse-Immuno-Oncology (MIO) and the miSeq platform (Illumina). These kits allow the detection of the expression profile of 990 genes involved in the immune response against tumors in humans and mice. The data were analyzed through the CLCbio Genomics Workbench (Qiagen) software using the Canis lupus familiaris genome as a reference. Data analysis were carried out both comparing the biologic group (tumoral vs. healthy tissues) and comparing neoplastic tissue vs. paired healthy tissue; a Fold Change greater than two and a p-value less than 0.05 were set as the threshold to select interesting genes. Results and Discussion: Using HIO 63, down-regulated genes were detected; 13 of those were also down-regulated comparing neoplastic sample vs. paired healthy tissue. Eighteen genes were up-regulated, 14 of those were also down-regulated comparing neoplastic sample vs. paired healthy tissue. Using the MIO, 35 down regulated-genes were detected; only four of these were down-regulated, also comparing neoplastic sample vs. paired healthy tissue. Twelve genes were up-regulated in both types of analysis. Considering the two kits, the greatest variation in Fold Change was in up-regulated genes. Dogs displayed a greater genetic homology with humans than mice; moreover, the results have shown that the two kits are able to detect different genes. Most of these genes have specific cellular functions or belong to some enzymatic categories; some have already been described to be correlated to human melanoma and confirm the validity of the dog as a model for the study of molecular aspects of human melanoma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=animal%20model" title="animal model">animal model</a>, <a href="https://publications.waset.org/abstracts/search?q=canine%20melanoma" title=" canine melanoma"> canine melanoma</a>, <a href="https://publications.waset.org/abstracts/search?q=gene%20expression" title=" gene expression"> gene expression</a>, <a href="https://publications.waset.org/abstracts/search?q=spontaneous%20tumors" title=" spontaneous tumors"> spontaneous tumors</a>, <a href="https://publications.waset.org/abstracts/search?q=targeted%20RNAseq" title=" targeted RNAseq"> targeted RNAseq</a> </p> <a href="https://publications.waset.org/abstracts/141871/analysis-of-differentially-expressed-genes-in-spontaneously-occurring-canine-melanoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141871.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">199</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Stromal Vascular Fraction Regenerative Potential in a Muscle Ischemia/Reperfusion Injury Mouse Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anita%20Conti">Anita Conti</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Ossanna"> Riccardo Ossanna</a>, <a href="https://publications.waset.org/abstracts/search?q=Lindsey%20A.%20Quintero"> Lindsey A. Quintero</a>, <a href="https://publications.waset.org/abstracts/search?q=Giamaica%20Conti"> Giamaica Conti</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Sbarbati"> Andrea Sbarbati</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ischemia/reperfusion (IR) injury induces muscle fiber atrophy and skeletal muscle fiber death with subsequently functionality loss. The heterogeneous pool of cells, especially mesenchymal stem cells, contained in the stromal vascular fraction (SVF) of adipose tissue could promote muscle fiber regeneration. To prevent SVF dispersion, it has been proposed the use of injectable biopolymers that work as cells carrier. A significant element of the extracellular matrix is hyaluronic acid (HA), which has been widely used in regenerative medicine as a cell scaffold given its biocompatibility, degradability, and the possibility of chemical functionalization. Connective tissue micro-fragments enriched with SVF obtained from mechanical disaggregation of adipose tissue were evaluated for IR muscle injury regeneration using low molecular weight HA as a scaffold. IR induction. Hindlimb ischemia was induced in 9 athymic nude mice through the clamping of the right quadriceps using a plastic band. Reperfusion was induced by cutting the plastic band after 3 hours of ischemic period. Contralateral (left) muscular tissue was used as healthy control. Treatment. Twenty-four hours after the IR induction, animals (n=3) were intramuscularly injected with 100 µl of SVF mixed with HA (SVF-HA). Animals treated with 100 µl of HA (n=3) and 100 µl saline solution (n=3) were used as control. Treatment monitoring. All animals were in vivo monitored by magnetic resonance imaging (MRI) at 5, 7, 14 and 18 days post-injury (dpi). High-resolution morphological T2 weighed, quantitative T2 map and Dynamic Contrast-Enhanced (DCE) images were acquired in order to assess the regenerative potential of SVF-HA treatment. Ex vivo evaluation. After 18 days from IR induction, animals were sacrificed, and the muscles were harvested for histological examination. At 5 dpi T2 high-resolution MR images clearly reveal the presence of an extensive edematous area due to IR damage for all groups identifiable as an increase of signal intensity (SI) of muscular and surrounding tissue. At 7 dpi, animals of the SVF-HA group showed a reduction of SI, and the T2relaxation time of muscle tissue of the HA-SVF group was 29±0.5ms, comparable with the T2relaxation time of contralateral muscular tissue (30±0.7ms). These suggest a reduction of edematous overflow and swelling. The T2relaxation time at 7dpi of HA and saline groups were 84±2ms and 90±5ms, respectively, which remained elevated during the rest of the study. The evaluation of vascular regeneration showed similar results. Indeed, DCE-MRI analysis revealed a complete recovery of muscular tissue perfusion after 14 dpi for the SVF-HA group, while for the saline and HA group, controls remained in a damaged state. Finally, the histological examination of SVF-HA treated animals exhibited well-defined and organized fibers morphology with a lateralized nucleus, similar to contralateral healthy muscular tissue. On the contrary, HA and saline-treated animals presented inflammatory infiltrates, with HA slightly improving the diameter of the fibers and less degenerated tissue. Our findings show that connective tissue micro-fragments enriched with SVF induce higher muscle homeostasis and perfusion restoration in contrast to control groups. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ischemia%2Freperfusion%20injury" title="ischemia/reperfusion injury">ischemia/reperfusion injury</a>, <a href="https://publications.waset.org/abstracts/search?q=regenerative%20medicine" title=" regenerative medicine"> regenerative medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=resonance%20imaging" title=" resonance imaging"> resonance imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=stromal%20vascular%20fraction" title=" stromal vascular fraction"> stromal vascular fraction</a> </p> <a href="https://publications.waset.org/abstracts/151594/stromal-vascular-fraction-regenerative-potential-in-a-muscle-ischemiareperfusion-injury-mouse-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151594.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Environmental Fate and Toxicity of Aged Titanium Dioxide Nano-Composites Used in Sunscreen</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Danielle%20Slomberg">Danielle Slomberg</a>, <a href="https://publications.waset.org/abstracts/search?q=Jerome%20Labille"> Jerome Labille</a>, <a href="https://publications.waset.org/abstracts/search?q=Riccardo%20Catalano"> Riccardo Catalano</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Claude%20Hubaud"> Jean-Claude Hubaud</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexandra%20Lopes"> Alexandra Lopes</a>, <a href="https://publications.waset.org/abstracts/search?q=Alice%20Tagliati"> Alice Tagliati</a>, <a href="https://publications.waset.org/abstracts/search?q=Teresa%20Fernandes"> Teresa Fernandes</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the assessment and management of cosmetics and personal care products, sunscreens are of emerging concern regarding both human and environmental health. Organic UV blockers in many sunscreens have been evidenced to undergo rapid photodegradation, induce dermal allergic reactions due to skin penetration, and to cause adverse effects on marine systems. While mineral UV-blockers may offer a safer alternative, their fate and impact and resulting regulation are still under consideration, largely related to the potential influence of nanotechnology-based products on both consumers and the environment. Nanometric titanium dioxide (TiO₂) UV-blockers have many advantages in terms of sun protection and asthetics (i.e., transparency). These UV-blockers typically consist of rutile nanoparticles coated with a primary mineral layer (silica or alumina) aimed at blocking the nanomaterial photoactivity and can include a secondary organic coating (e.g., stearic acid, methicone) aimed at favouring dispersion of the nanomaterial in the sunscreen formulation. The nanomaterials contained in the sunscreen can leave the skin either through a bathing of everyday usage, with subsequent release into rivers, lakes, seashores, and/or sewage treatment plants. The nanomaterial behaviour, fate and impact in these different systems is largely determined by its surface properties, (e.g. the nanomaterial coating type) and lifetime. The present work aims to develop the eco-design of sunscreens through the minimisation of risks associated with nanomaterials incorporated into the formulation. All stages of the sunscreen’s life cycle must be considered in this aspect, from its manufacture to its end-of-life, through its use by the consumer to its impact on the exposed environment. Reducing the potential release and/or toxicity of the nanomaterial from the sunscreen is a decisive criterion for its eco-design. TiO₂ UV-blockers of varied size and surface coating (e.g., stearic acid and silica) have been selected for this study. Hydrophobic TiO₂ UV-blockers (i.e., stearic acid-coated) were incorporated into a typical water-in-oil (w/o) formulation while hydrophilic, silica-coated TiO₂ UV-blockers were dispersed into an oil-in-water (o/w) formulation. The resulting sunscreens were characterised in terms of nanomaterial localisation, sun protection factor, and photo-passivation. The risk to the direct aquatic environment was assessed by evaluating the release of nanomaterials from the sunscreen through a simulated laboratory aging procedure. The size distribution, surface charge, and degradation state of the nano-composite by-products, as well as their nanomaterial concentration and colloidal behaviour were determined in a variety of aqueous environments (e.g., seawater and freshwater). Release of the hydrophobic nanocomposites into the aqueous environment was driven by oil droplet formation while hydrophilic nano-composites were readily dispersed. Ecotoxicity of the sunscreen by-products (from both w/o and o/w formulations) and their risk to marine organisms were assessed using coral symbiotes and tropical corals, evaluating both lethal and sublethal toxicities. The data dissemination and provided risk knowledge from the present work will help guide regulation related to nanomaterials in sunscreen, provide better information for consumers, and allow for easier decision-making for manufacturers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alteration" title="alteration">alteration</a>, <a href="https://publications.waset.org/abstracts/search?q=environmental%20fate" title=" environmental fate"> environmental fate</a>, <a href="https://publications.waset.org/abstracts/search?q=sunscreens" title=" sunscreens"> sunscreens</a>, <a href="https://publications.waset.org/abstracts/search?q=titanium%20dioxide%20nanoparticles" title=" titanium dioxide nanoparticles"> titanium dioxide nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/72783/environmental-fate-and-toxicity-of-aged-titanium-dioxide-nano-composites-used-in-sunscreen" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/72783.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">262</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">&copy; 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