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The findings, <a href="https://www.nature.com/nm/journal/vaop/ncurrent/full/nm.2669.html">reported online</a> today (26 February) in <em>Nature Medicine</em>, could lead to new therapies that help extend female fertility into late middle age and beyond.</p> <p>“For women’s reproductive health these findings have so many ramifications,” says study author <a href="https://www.massgeneral.org/vcrb/staff/Tilly.aspx">Jonathan Tilly</a>, a reproductive biologist at the Massachusetts General Hospital and the Harvard Medical School in Boston. “If we can get to the stage of generating functional human eggs outside the body, it would essentially rewrite human assisted reproduction.”</p> </div> </section> <div class="wpn-entry-meta"> <aside> <div class="article-tools cleared"> <h2 class="hidden">Article tools</h2> <ul id="wpn-share-post-2549" class="wpn-entry-user-actions"> <li class="wpn-entry-comment-link"><a class="comments-link" 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market</a></div></li> </ul></div></nav> </div> </article>  <section> <div class="section expanded cleared" id="comments"> <h1 class="section-heading toggle">Comments</h1> <div class="content">  <ol class="wpn-comment-list comments ugc cleared"> <li id="comment-599" class="wpn-comment wpn-byuser wpn-comment-author-musarrat-shahreen wpn-even wpn-thread-even wpn-depth-1 wpn-role-subscriber wpn-user-musarrat-shahreen box"> <article>  <div class="wpn-comment-meta wpn-upper"><p class="datetime"><time datetime="2012-03-01T10:41:24-05:00" pubdate><abbr class="published" title="2012-03-01T10:41:24-0500">01 Mar 2012 10:41 EST</abbr></time></p><p class="moderation"> <a class="report" href="?action=report&comment=599#comment-599">Report this comment</a> </p> </div><dl> <dt><span class="comment-author vcard"><cite class="fn">musarrat shahreen</cite> said: </span></dt> <dd><p> This is helpfull for those womens suffering from premature ovarian failure.</p> </dd> </dl><div class="wpn-comment-meta 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value='https://blogs.nature.com/spoonful/2014/10'> October 2014  (1)</option><option value='https://blogs.nature.com/spoonful/2014/08'> August 2014  (1)</option><option value='https://blogs.nature.com/spoonful/2014/07'> July 2014  (1)</option><option value='https://blogs.nature.com/spoonful/2014/06'> June 2014  (1)</option><option value='https://blogs.nature.com/spoonful/2014/05'> May 2014  (2)</option><option value='https://blogs.nature.com/spoonful/2014/04'> April 2014  (3)</option><option value='https://blogs.nature.com/spoonful/2014/03'> March 2014  (6)</option><option value='https://blogs.nature.com/spoonful/2014/02'> February 2014  (3)</option><option value='https://blogs.nature.com/spoonful/2014/01'> January 2014  (3)</option><option value='https://blogs.nature.com/spoonful/2013/10'> October 2013  (4)</option><option value='https://blogs.nature.com/spoonful/2013/09'> September 2013  (11)</option><option value='https://blogs.nature.com/spoonful/2013/08'> August 2013  (4)</option><option value='https://blogs.nature.com/spoonful/2013/07'> July 2013  (5)</option><option value='https://blogs.nature.com/spoonful/2013/06'> June 2013  (4)</option><option value='https://blogs.nature.com/spoonful/2013/04'> April 2013  (3)</option><option value='https://blogs.nature.com/spoonful/2013/03'> March 2013  (12)</option><option value='https://blogs.nature.com/spoonful/2013/02'> February 2013  (13)</option><option value='https://blogs.nature.com/spoonful/2013/01'> January 2013  (12)</option><option value='https://blogs.nature.com/spoonful/2012/12'> December 2012  (11)</option><option value='https://blogs.nature.com/spoonful/2012/11'> November 2012  (8)</option><option value='https://blogs.nature.com/spoonful/2012/10'> October 2012  (6)</option><option value='https://blogs.nature.com/spoonful/2012/09'> September 2012  (3)</option><option value='https://blogs.nature.com/spoonful/2012/08'> August 2012  (10)</option><option value='https://blogs.nature.com/spoonful/2012/07'> July 2012  (12)</option><option value='https://blogs.nature.com/spoonful/2012/06'> June 2012  (9)</option><option value='https://blogs.nature.com/spoonful/2012/05'> May 2012  (6)</option><option value='https://blogs.nature.com/spoonful/2012/04'> April 2012  (10)</option><option value='https://blogs.nature.com/spoonful/2012/03'> March 2012  (11)</option><option value='https://blogs.nature.com/spoonful/2012/02'> February 2012  (8)</option><option value='https://blogs.nature.com/spoonful/2012/01'> January 2012  (14)</option><option value='https://blogs.nature.com/spoonful/2011/12'> December 2011  (19)</option><option value='https://blogs.nature.com/spoonful/2011/11'> November 2011  (26)</option><option value='https://blogs.nature.com/spoonful/2011/10'> October 2011  (32)</option><option value='https://blogs.nature.com/spoonful/2011/09'> September 2011  (33)</option><option value='https://blogs.nature.com/spoonful/2011/08'> August 2011  (37)</option><option value='https://blogs.nature.com/spoonful/2011/07'> July 2011  (39)</option><option value='https://blogs.nature.com/spoonful/2011/06'> June 2011  (41)</option><option value='https://blogs.nature.com/spoonful/2011/05'> May 2011  (35)</option><option value='https://blogs.nature.com/spoonful/2011/04'> April 2011  (40)</option><option value='https://blogs.nature.com/spoonful/2011/03'> March 2011  (51)</option><option value='https://blogs.nature.com/spoonful/2011/02'> February 2011  (42)</option><option value='https://blogs.nature.com/spoonful/2011/01'> January 2011  (35)</option><option value='https://blogs.nature.com/spoonful/2010/12'> December 2010  (24)</option><option value='https://blogs.nature.com/spoonful/2010/11'> November 2010  (32)</option><option value='https://blogs.nature.com/spoonful/2010/10'> October 2010  (40)</option><option value='https://blogs.nature.com/spoonful/2010/09'> September 2010  (35)</option><option value='https://blogs.nature.com/spoonful/2010/08'> August 2010  (48)</option><option value='https://blogs.nature.com/spoonful/2010/07'> July 2010  (55)</option><option value='https://blogs.nature.com/spoonful/2010/06'> June 2010  (70)</option><option value='https://blogs.nature.com/spoonful/2010/05'> May 2010  (56)</option><option value='https://blogs.nature.com/spoonful/2010/04'> April 2010  (65)</option><option value='https://blogs.nature.com/spoonful/2010/03'> March 2010  (59)</option><option value='https://blogs.nature.com/spoonful/2010/02'> February 2010  (43)</option><option value='https://blogs.nature.com/spoonful/2010/01'> January 2010  (29)</option><option value='https://blogs.nature.com/spoonful/2009/12'> December 2009  (31)</option><option value='https://blogs.nature.com/spoonful/2009/11'> November 2009  (7)</option><option value='https://blogs.nature.com/spoonful/2009/10'> October 2009  (2)</option><option value='https://blogs.nature.com/spoonful/2009/09'> September 2009  (5)</option><option value='https://blogs.nature.com/spoonful/2009/08'> August 2009  (1)</option><option value='https://blogs.nature.com/spoonful/2009/07'> July 2009  (2)</option><option value='https://blogs.nature.com/spoonful/2009/06'> June 2009  (3)</option><option value='https://blogs.nature.com/spoonful/2009/05'> May 2009  (2)</option><option value='https://blogs.nature.com/spoonful/2009/04'> April 2009  (6)</option><option value='https://blogs.nature.com/spoonful/2009/03'> March 2009  (7)</option><option value='https://blogs.nature.com/spoonful/2009/02'> February 2009  (4)</option><option value='https://blogs.nature.com/spoonful/2009/01'> January 2009  (10)</option><option value='https://blogs.nature.com/spoonful/2008/12'> December 2008  (1)</option><option value='https://blogs.nature.com/spoonful/2008/11'> November 2008  (5)</option><option value='https://blogs.nature.com/spoonful/2008/10'> October 2008  (8)</option><option value='https://blogs.nature.com/spoonful/2008/09'> September 2008  (2)</option><option value='https://blogs.nature.com/spoonful/2008/08'> August 2008  (4)</option><option value='https://blogs.nature.com/spoonful/2008/07'> July 2008  (7)</option><option value='https://blogs.nature.com/spoonful/2008/06'> June 2008  (5)</option><option value='https://blogs.nature.com/spoonful/2008/05'> May 2008  (8)</option><option value='https://blogs.nature.com/spoonful/2008/04'> April 2008  (7)</option><option value='https://blogs.nature.com/spoonful/2008/03'> March 2008  (24)</option><option value='https://blogs.nature.com/spoonful/2008/02'> February 2008  (16)</option><option value='https://blogs.nature.com/spoonful/2008/01'> January 2008  (1)</option><option value='https://blogs.nature.com/spoonful/2007/12'> December 2007  (9)</option><option value='https://blogs.nature.com/spoonful/2007/11'> November 2007  (5)</option><option value='https://blogs.nature.com/spoonful/2007/10'> October 2007  (12)</option><option value='https://blogs.nature.com/spoonful/2007/09'> September 2007  (5)</option><option value='https://blogs.nature.com/spoonful/2007/08'> August 2007  (13)</option><option value='https://blogs.nature.com/spoonful/2007/07'> July 2007  (3)</option><option value='https://blogs.nature.com/spoonful/2007/06'> June 2007  (5)</option><option value='https://blogs.nature.com/spoonful/2007/05'> May 2007  (3)</option><option value='https://blogs.nature.com/spoonful/2007/04'> April 2007  (5)</option><option value='https://blogs.nature.com/spoonful/2007/03'> March 2007  (17)</option><option value='https://blogs.nature.com/spoonful/2007/02'> February 2007  (12)</option><option value='https://blogs.nature.com/spoonful/2007/01'> January 2007  (11)</option><option value='https://blogs.nature.com/spoonful/2006/12'> December 2006  (10)</option></select> </div> </div><div id="wpn-npg-author-list-widget-2" class="wpn-widget wpn-npg-author-list-widget wpn- wpn-archive-selector clear"> <div class="wpn-widget-content"><select name="author-archive-dropdown" onchange="location.href=this.options[this.selectedIndex].value"> <option value="">Select author</option><option value="https://blogs.nature.com/spoonful/author/akatsnelson1">Alla Katsnelson  (1)</option><option value="https://blogs.nature.com/spoonful/author/Amanda-Keener">Amanda Keener  (2)</option><option value="https://blogs.nature.com/spoonful/author/amaxmen">Amy Maxmen  (1)</option><option value="https://blogs.nature.com/spoonful/author/Anna-Azvolinsky">Anna Azvolinsky  (1)</option><option value="https://blogs.nature.com/spoonful/author/Cassandra-Willyard">Cassandra Willyard  (4)</option><option value="https://blogs.nature.com/spoonful/author/devinscience">Devin Powell  (1)</option><option value="https://blogs.nature.com/spoonful/author/hannahh">Hannah Hoag  (1)</option><option value="https://blogs.nature.com/spoonful/author/Killugudi-Jayaraman">Killugudi Jayaraman  (1)</option><option value="https://blogs.nature.com/spoonful/author/megan">Megan Scudellari  (1)</option><option value="https://blogs.nature.com/spoonful/author/mohebcostandi">Mo Costandi  (1)</option><option value="https://blogs.nature.com/spoonful/author/Nature-Medicine-Editor">Nature Medicine Editor  (61)</option><option value="https://blogs.nature.com/spoonful/author/randy-levison">Randy Levison  (2)</option><option value="https://blogs.nature.com/spoonful/author/Roxanne-Khamsi">Roxanne Khamsi  (1)</option><option value="https://blogs.nature.com/spoonful/author/roxanne-khamsi-2">Roxanne Khamsi  (14)</option><option value="https://blogs.nature.com/spoonful/author/Susan-Matthews">Susan Matthews  (6)</option><option value="https://blogs.nature.com/spoonful/author/Virginia-Hughes">Virginia Hughes  (1)</option></select> </div> </div><div id="wpn-hybrid-categories-3" class="wpn-widget wpn-categories wpn-"><h2 class="box-heading">Categories</h2><ul class="xoxo categories"><li class="cat-item cat-item-11"><a href="https://blogs.nature.com/spoonful/category/aids" >AIDS</a></li><li class="cat-item cat-item-27"><a href="https://blogs.nature.com/spoonful/category/campaign-2008" >Campaign 2008</a></li><li class="cat-item cat-item-6"><a href="https://blogs.nature.com/spoonful/category/cancer" >Cancer</a></li><li class="cat-item cat-item-28"><a href="https://blogs.nature.com/spoonful/category/daily-dose" >Daily Dose</a></li><li class="cat-item cat-item-13"><a href="https://blogs.nature.com/spoonful/category/diabetes-and-metabolism" >Diabetes and metabolism</a></li><li class="cat-item cat-item-7"><a href="https://blogs.nature.com/spoonful/category/drugs-drugs-and-more-drugs" >Drugs, drugs and more drugs</a></li><li class="cat-item cat-item-25"><a href="https://blogs.nature.com/spoonful/category/environment" >Environment</a></li><li class="cat-item cat-item-29"><a href="https://blogs.nature.com/spoonful/category/featured" >Featured</a></li><li class="cat-item cat-item-4"><a href="https://blogs.nature.com/spoonful/category/genetics" >Genetics</a></li><li class="cat-item cat-item-136"><a href="https://blogs.nature.com/spoonful/category/infectious-diseases" >Infectious diseases</a></li><li class="cat-item cat-item-26"><a href="https://blogs.nature.com/spoonful/category/journal-club" >Journal club</a></li><li class="cat-item cat-item-20"><a href="https://blogs.nature.com/spoonful/category/malaria" >Malaria</a></li><li class="cat-item cat-item-137"><a href="https://blogs.nature.com/spoonful/category/microbiology" >Microbiology</a></li><li class="cat-item cat-item-10"><a href="https://blogs.nature.com/spoonful/category/neurosciencemental-health" >Neuroscience/mental health</a></li><li class="cat-item cat-item-9"><a href="https://blogs.nature.com/spoonful/category/odds-and-ends" >Odds and ends</a></li><li class="cat-item cat-item-12"><a href="https://blogs.nature.com/spoonful/category/podcasts" >Podcasts</a></li><li class="cat-item cat-item-5"><a href="https://blogs.nature.com/spoonful/category/policy" >Policy</a></li><li class="cat-item cat-item-3"><a href="https://blogs.nature.com/spoonful/category/print" >Print</a></li><li class="cat-item cat-item-15"><a href="https://blogs.nature.com/spoonful/category/scientific-publishing" >Scientific publishing</a></li><li class="cat-item cat-item-8"><a href="https://blogs.nature.com/spoonful/category/stem-cellscloning" >Stem cells/cloning</a></li><li class="cat-item cat-item-17"><a href="https://blogs.nature.com/spoonful/category/swine-flu" >swine flu</a></li><li class="cat-item cat-item-19"><a href="https://blogs.nature.com/spoonful/category/tuberculosis" >Tuberculosis</a></li><li class="cat-item cat-item-1"><a href="https://blogs.nature.com/spoonful/category/uncategorized" >Uncategorized</a></li><li class="cat-item cat-item-18"><a href="https://blogs.nature.com/spoonful/category/video" >Video</a></li><li class="cat-item cat-item-135"><a href="https://blogs.nature.com/spoonful/category/virology" >Virology</a></li><li class="cat-item cat-item-14"><a href="https://blogs.nature.com/spoonful/category/womens-world" >Women's world</a></li><li class="cat-item cat-item-16"><a href="https://blogs.nature.com/spoonful/category/world-watch" >World watch</a></li></ul></div><div id="wpn-npg-natureblogs-links-widget-2" class="wpn-widget wpn-npg-natureblogs-links-widget wpn-">