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Hassen</title> <meta name="description" content="Search results for: Mohamed Ben Hassen"> <meta name="keywords" content="Mohamed Ben Hassen"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Mohamed Ben Hassen"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1624</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Mohamed Ben Hassen</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1504</span> Process of Dimensioning Small Type Annular Combustors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saleh%20B.%20Mohamed">Saleh B. Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20H.%20Elhsnawi"> Mohamed H. Elhsnawi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mesbah%20M.%20Salem"> Mesbah M. Salem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Current and future applications of small gas turbine engines annular type combustors have requirements presenting difficult disputes to the combustor designer. Reduced cost and fuel consumption and improved durability and reliability as well as higher temperatures and pressures for such application are forecast. Coupled with these performance requirements, irrespective of the engine size, is the demand to control the pollutant emissions, namely the oxides of nitrogen, carbon monoxide, smoke and unburned hydrocarbons. These technical and environmental challenges have made the design of small size combustion system a very hard task. Thus, the main target of this work is to generalize a calculation method of annular type combustors for small gas turbine engines that enables to understand the fundamental concepts of the coupled processes and to identify the proper procedure that formulates and solves the problems in combustion fields in as much simplified and accurate manner as possible. The combustion chamber in task is designed with central vaporizing unit and to deliver 516.3 KW of power. The geometrical constraints are 142 mm & 140 mm overall length and casing diameter, respectively, while the airflow rate is 0.8 kg/sec and the fuel flow rate is 0.012 kg/sec. The relevant design equations are programmed by using MathCAD language for ease and speed up of the calculation process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=design%20of%20gas%20turbine" title="design of gas turbine">design of gas turbine</a>, <a href="https://publications.waset.org/abstracts/search?q=small%20engine%20design" title=" small engine design"> small engine design</a>, <a href="https://publications.waset.org/abstracts/search?q=annular%20type%20combustors" title=" annular type combustors"> annular type combustors</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20engineering" title=" mechanical engineering"> mechanical engineering</a> </p> <a href="https://publications.waset.org/abstracts/8537/process-of-dimensioning-small-type-annular-combustors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8537.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">408</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1503</span> Socioeconomic Values of Fertility in Islam</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Hamed%20Mohamed%20Ahmed%20Alameer">Mohamed Hamed Mohamed Ahmed Alameer</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Population studies, essentially deals with the size, growth, and distribution of the population in a given area. Size, growth, and distribution are determined by three major factors, which are fertility mortality, and migration. Of these factors, fertility- as a number of live births a woman has actually had- is a potent socio-demographic force in vital process of population growth. So, fertility is a major component of population growth. It is one of the main determinants of population growth and has crucial role in population dynamic, because it measures the rate at which a population increased. In fact the levels of fertility are vary widely among nations, countries, geographic regions, ethnic, socio- economic groups, and religious groups. Fertility differential by religion have been empirically documented in a large numbers of countries. For instance, many researchers in developing and developed countries investigated the differential of fertility among Muslims and Non- Muslims. Most of them have found that fertility of Muslims is higher than fertility of non Muslims. And Muslims have a tendency for large families comparing to non- Muslims population. On the basis of this; Islam by it itself could play an important role in shaping attitudes and values of fertility, such as: sustainability of human kind, developmental reasons, religious Motivations, socioeconomic Motivations, and Psychological Motivation. Therefore, this paper investigates socio-economic values of fertility in Islam and compare it to Malthusian and neo Malthusian functionalists and conflict perspectives. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=islam" title="islam">islam</a>, <a href="https://publications.waset.org/abstracts/search?q=fertility" title=" fertility"> fertility</a>, <a href="https://publications.waset.org/abstracts/search?q=socioeconomic%20values" title=" socioeconomic values"> socioeconomic values</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20sciences" title=" social sciences"> social sciences</a> </p> <a href="https://publications.waset.org/abstracts/21537/socioeconomic-values-of-fertility-in-islam" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21537.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">474</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1502</span> Impact of El-Matrouha Landfill on Oued El-Kebir (North East of Algeria)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Djalil%20Zaafour">Mohamed Djalil Zaafour</a>, <a href="https://publications.waset.org/abstracts/search?q=Samir%20Chekchaki"> Samir Chekchaki</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Benslama"> Mohamed Benslama</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Landfill of El Matrouha is located in El-Tarf town (extreme north east of Algeria), the Landfill is present as a gigantic wild dump. This waste dump occupies an area of over four hectares, tons of rubbish that is sent daily are scattered over kilometers, reaching farmland located west of the town, the landfill is close to a temporary Oued, which supply Oued Guergour the last tributary Oued El Kebir. The landfills are causing serious environmental damage, following the infiltration of leachates, which contribute to the degradation of water quality, in the context of this problem, the purpose of the work is focused on assessing the impact of this landfill on Oued El-Kebir, for this a series of sampling and analysis of the soil and water of this Oued was performed; The results show that the soil collected reveal the sandy texture facilitating infiltration and percolation of leachate from the landfill; the physicochemical analysis of the quality of the river water reveals high levels of sulfates in fact this element is one of the essential constituents of the mineral fraction of the waste presenting a risk of pollution by this element, The recorded values for nutrients are sub-standard, for trace elements analysis shows very low metal load on the river except for lead, which is present at high concentrations exceeding all standard. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Algeria" title="Algeria">Algeria</a>, <a href="https://publications.waset.org/abstracts/search?q=landfill" title=" landfill"> landfill</a>, <a href="https://publications.waset.org/abstracts/search?q=leachates" title=" leachates"> leachates</a>, <a href="https://publications.waset.org/abstracts/search?q=Oued%20El-kebir" title=" Oued El-kebir"> Oued El-kebir</a> </p> <a href="https://publications.waset.org/abstracts/40268/impact-of-el-matrouha-landfill-on-oued-el-kebir-north-east-of-algeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40268.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">369</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1501</span> Topical Negative Pressure for Autologous Fat Grafting in Breast Augmentation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Eftal%20Bin%20Mohamed%20Ebrahim">Mohamed Eftal Bin Mohamed Ebrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Varey"> Alexander Varey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aim: Topical negative pressure has been shown to enhance angiogenesis during wound healing, both for open and closed wounds. Since angiogenesis is a key requirement for successful fat grafting, there may be a role for topical negative pressure as a means of enhancing the take rate during autologous fat grafting to breasts. Here we present a systematic review of the literature on this topic. Methods: Ovid and Embase were utilized, with searches ranging between 1960 – 2019. Terms (“Liposculpting” OR “Fat grafting” OR “Lipofilling” OR “Lipograft” OR “Fat transfer”) AND (“Negative Pressure” OR “Brava” OR “Kiwi”) AND (“Breast”) were merged as keywords. Inclusion criteria were females, autologous fat graft to breast with topical negative pressure prior to the procedure. Studies were excluded if there was no primary endpoint or non-original article. Results: Upon reviewing 219 articles, 2 met inclusion criteria. A total of 565 and 46 breasts in each article were treated respectively using the negative pressure device BRAVA®, with each cohort having different pre-and post-operative pressure settings. Khouri et al. cohort had higher graft survival (79%) compared to Del Vecchio et al. cohort (64%); however, the latter had fewer complications compared to Khouri’s cohort, e.g., fat necrosis, pneumothorax and infection. Conclusion: There is limited evidence regarding the use of topical negative pressure for fat grafting to the breasts. However, in the two studies published, the reported rates of success are high, suggesting there may be a benefit. Consequently, a randomized controlled trial on this area is required. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fat%20grafting" title="fat grafting">fat grafting</a>, <a href="https://publications.waset.org/abstracts/search?q=lipograft" title=" lipograft"> lipograft</a>, <a href="https://publications.waset.org/abstracts/search?q=negative%20pressure" title=" negative pressure"> negative pressure</a>, <a href="https://publications.waset.org/abstracts/search?q=breast" title=" breast"> breast</a>, <a href="https://publications.waset.org/abstracts/search?q=breast%20augmentation" title=" breast augmentation"> breast augmentation</a>, <a href="https://publications.waset.org/abstracts/search?q=brava" title=" brava"> brava</a> </p> <a href="https://publications.waset.org/abstracts/140958/topical-negative-pressure-for-autologous-fat-grafting-in-breast-augmentation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140958.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">192</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1500</span> The Nexus between Migration and Human Security: The Case of Ethiopian Female Migration to Sudan</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anwar%20Hassen%20Tsega">Anwar Hassen Tsega</a> </p> <p class="card-text"><strong>Abstract:</strong></p> International labor migration is an integral part of the modern globalized world. However, the phenomenon has its roots in some earlier periods in human history. This paper discusses the relatively new phenomenon of female migration in Africa. In the past, African women migrants were only spouses or dependent family members. But as modernity swept most African societies, with rising unemployment rates, there is evidence everywhere in Africa that women labor migration is a growing phenomenon that deserves to be understood in the context of human security research. This work explores these issues further, focusing on the experience of Ethiopian women labor migrants to Sudan. The migration of Ethiopian people to Sudan is historical; nevertheless, labor migration mainly started since the discovery and subsequent exploration of oil in the Sudan. While the paper is concerned with the human security aspect of the migrant workers, we need to be certain that the migration process will provide with a decent wage, good working conditions, the necessary social security coverage, and labor protection as a whole. However, migration to Sudan is not always safe and female migrants become subject to violence at the hands of brokers, employers and migration officials. For this matter, the paper argued that identifying the vulnerable stages and major problem facing female migrant workers at various stages of migration is a prerequisite to combat the problem and secure the lives of the migrant workers. The major problems female migrants face include extra degrees of gender-based violence, underpayment, various forms of abuse like verbal, physical and sexual and other forms of torture which include beating and slaps. This peculiar situation could be attributed to the fact that most of these women are irregular migrants and fall under the category of unskilled and/or illiterate migrants. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ethiopia" title="Ethiopia">Ethiopia</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20security" title=" human security"> human security</a>, <a href="https://publications.waset.org/abstracts/search?q=labor%20migration" title=" labor migration"> labor migration</a>, <a href="https://publications.waset.org/abstracts/search?q=Sudan" title=" Sudan"> Sudan</a> </p> <a href="https://publications.waset.org/abstracts/43807/the-nexus-between-migration-and-human-security-the-case-of-ethiopian-female-migration-to-sudan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43807.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">251</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1499</span> Digital Design and Fabrication: A Review of Trend and Its Impact in the African Context</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Al%20Araby">Mohamed Al Araby</a>, <a href="https://publications.waset.org/abstracts/search?q=Amany%20Salman"> Amany Salman</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Amin"> Mostafa Amin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Madbully"> Mohamed Madbully</a>, <a href="https://publications.waset.org/abstracts/search?q=Dalia%20Keraa"> Dalia Keraa</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariam%20Ali"> Mariam Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Marah%20Abdelfatah"> Marah Abdelfatah</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariam%20Ahmed"> Mariam Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Hassab"> Ahmed Hassab</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, the architecture, engineering, and construction (A.E.C.) industry have been exposed to important innovations, most notably the global integration of digital design and fabrication (D.D.F.) processes in the industry’s workflow. Despite this evolution in that sector, Africa was excluded from the examination of this development. The reason behind this exclusion is the preconceived view of it as a developing region that still employs traditional methods of construction. The primary objective of this review is to investigate the trend of digital construction (D.C.) in the African environment and the difficulties in its regular utilization of it. This objective can be attained by recognizing the notion of distributed computing in Africa and evaluating the impact of the projects deploying this technology on both the immediate and broader contexts. The paper’s methodology begins with the collection of data from 224 initiatives throughout Africa. Then, 50 of these projects were selected based on the criteria of the project's recency, typology variety, and location diversity. After that, a literature-based comparative analysis was undertaken. This study’s findings reveal a pattern of motivation for applying digital fabrication processes. Moreover, it is essential to evaluate the socio-economic effects of these projects on the population living near the analyzed subject. The last step in this study is identifying the influence on the neighboring nations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Africa" title="Africa">Africa</a>, <a href="https://publications.waset.org/abstracts/search?q=digital%20construction" title=" digital construction"> digital construction</a>, <a href="https://publications.waset.org/abstracts/search?q=digital%20design" title=" digital design"> digital design</a>, <a href="https://publications.waset.org/abstracts/search?q=fabrication" title=" fabrication"> fabrication</a> </p> <a href="https://publications.waset.org/abstracts/159434/digital-design-and-fabrication-a-review-of-trend-and-its-impact-in-the-african-context" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159434.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">177</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1498</span> Linear Decoding Applied to V5/MT Neuronal Activity on Past Trials Predicts Current Sensory Choices</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ben%20Hadj%20Hassen%20Sameh">Ben Hadj Hassen Sameh</a>, <a href="https://publications.waset.org/abstracts/search?q=Gaillard%20Corentin"> Gaillard Corentin</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20Parker"> Andrew Parker</a>, <a href="https://publications.waset.org/abstracts/search?q=Kristine%20Krug"> Kristine Krug</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Perceptual decisions about sequences of sensory stimuli often show serial dependence. The behavioural choice on one trial is often affected by the choice on previous trials. We investigated whether the neuronal signals in extrastriate visual area V5/MT on preceding trials might influence choice on the current trial and thereby reveal the neuronal mechanisms of sequential choice effects. We analysed data from 30 single neurons recorded from V5/MT in three Rhesus monkeys making sequential choices about the direction of rotation of a three-dimensional cylinder. We focused exclusively on the responses of neurons that showed significant choice-related firing (mean choice probability =0.73) while the monkey viewed perceptually ambiguous stimuli. Application of a wavelet transform to the choice-related firing revealed differences in the frequency band of neuronal activity that depended on whether the previous trial resulted in a correct choice for an unambiguous stimulus that was in the neuron’s preferred direction (low alpha and high beta and gamma) or non-preferred direction (high alpha and low beta and gamma). To probe this in further detail, we applied a regularized linear decoder to predict the choice for an ambiguous trial by referencing the neuronal activity of the preceding unambiguous trial. Neuronal activity on a previous trial provided a significant prediction of the current choice (61% correc, 95%Cl~52%t), even when limiting analysis to preceding trials that were correct and rewarded. These findings provide a potential neuronal signature of sequential choice effects in the primate visual cortex. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=perception" title="perception">perception</a>, <a href="https://publications.waset.org/abstracts/search?q=decision%20making" title=" decision making"> decision making</a>, <a href="https://publications.waset.org/abstracts/search?q=attention" title=" attention"> attention</a>, <a href="https://publications.waset.org/abstracts/search?q=decoding" title=" decoding"> decoding</a>, <a href="https://publications.waset.org/abstracts/search?q=visual%20system" title=" visual system"> visual system</a> </p> <a href="https://publications.waset.org/abstracts/154327/linear-decoding-applied-to-v5mt-neuronal-activity-on-past-trials-predicts-current-sensory-choices" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154327.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">139</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1497</span> Novel Oral Anticoagulants (NOACS) Adherence and Bleeding Events in Atrial Fibrillation Patients: A Systematic Review and Meta-Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tadesse%20Melaku%20Abegaz">Tadesse Melaku Abegaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Akshaya%20Srikanth%20Bahagavathula"> Akshaya Srikanth Bahagavathula</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdulla%20Shehab%20Sheab"> Abdulla Shehab Sheab</a>, <a href="https://publications.waset.org/abstracts/search?q=Asim%20Hassen"> Asim Hassen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: Non-adherence and discontinuation of anticoagulant therapy lead to increased ischemic stroke risk and contributes to suboptimal outcomes of the anticoagulant treatment. This systematic review and meta-analysis were aimed to investigate the adherence to NOACs and adverse events in patients with AF. Methods: Original research articles conducted on patients with AF and using any NOACs (dabigatran, rivoraxaban and apixaban) reporting adherence for at least 35 days were included. Scientific databases including PubMed, Web of Science, and Google Scholar were searched using MeSH keywords to obtaining literature researched between 2008 to till June, 2016. Study characteristics, patient’s sociodemographic and clinical characteristics, medication adherence levels and bleeding events reported were recorded. Results: The overall sample size of the six studies is 1,640,157, with CHADS2 scores < 2 in 551 patients, CHADS2-VASc ≥ 2 in 62,232 AF patients. Three-forth [75.6% (95%CI= 66.5-84.8), p < 0.001] are adherent to NOACs. However, a higher rate [72.7% (62.5-82.9), p < 0.001] of adherence was observed with Dabigatran than Apixaban [59.9% (3.2-123.1), p=0.063] and Rivaroxaban [59.3% (38.7-80.0), p<0.001]. Sub-group analysis revealed that nearly 57% of the AF patients on NOACs have CHADS2 scores < 2 and 20% of these patients were non-adherent to NOACs. Overall bleeding events rate associated with NOACs non-adherent AF patients was found to be 7.5% (0.2-14.8), p=0.045. However, nearly 11.2% of AF patients experienced bleeding events were non-adherent to NOAC medications. A higher proportion of bleeding events were noticed with Dabigatran (14.7%). Conclusions: Adherence rates, while uniformly suboptimal, nevertheless varied considerably, lowest at 59.3% for rivaroxaban and 59.9% for apixaban, followed by dabigatran (75.6%). Overall bleeding events associated with NOACs rates were 7.5%. However, lower adherence to NOACs was associated with worse outcomes among patients with greater stroke risk. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=atrial%20fibrillation" title="atrial fibrillation">atrial fibrillation</a>, <a href="https://publications.waset.org/abstracts/search?q=bleeding%20events" title=" bleeding events"> bleeding events</a>, <a href="https://publications.waset.org/abstracts/search?q=meta-analysis" title=" meta-analysis"> meta-analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=novel%20oral%20anticoagulants" title=" novel oral anticoagulants"> novel oral anticoagulants</a> </p> <a href="https://publications.waset.org/abstracts/62559/novel-oral-anticoagulants-noacs-adherence-and-bleeding-events-in-atrial-fibrillation-patients-a-systematic-review-and-meta-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62559.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">340</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1496</span> Enzymatic Biomonitoring of Aquatic Pollution at Jeddah Southern Red Sea Shore</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saleh%20Mohamed">Saleh Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20%20El-Shal"> Mohamed El-Shal</a>, <a href="https://publications.waset.org/abstracts/search?q=Taha%20%20Kumosani"> Taha Kumosani</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Mal"> Ahmad Mal</a>, <a href="https://publications.waset.org/abstracts/search?q=Youssri%20Ahmed"> Youssri Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Yasser%20Almulaiky"> Yasser Almulaiky</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The marine environment of the Jeddah southern red sea shore is subjected to increasing anthropogenic activities as sewage sludge draining and desalting processes. The objective of this study is to compare the quantitative responses of enzymatic biomarkers in fish from polluted area with the responses of organism from reference area. Enzymatic biomarkers as neurotoxic, antioxidant and detoxifying enzymes were evaluated in the brain and liver from Variola louti as a sentinel species sampled from both polluted and reference sites in the Jeddah southern red sea shore during four months January, April, July and October in 2014 and 2015. In brain of V. louti, the activity of acetylcholinestease (AChE) collected from reference area significantly increased 8.8 and 10.5 folds than that from polluted area in 2014 and 2015, respectively. The activities of catalase (CAT), glutathione reductase (GR) and glutathione peroxidase (GPx) and glutathione-S-transferase (GST) from liver of V. louti in polluted area significantly increased 1.4, 1.27 and 3, 4.5 and 4.37, 2 and 5, 4.5 folds than that from reference area in 2014 and 2015, respectively. The levels of examined enzymes are approximately similar in the four seasons detected in 2014 and 2015 indicating that the similar components of sewage were draining in red sea. In conclusion, these findings suggest the important of enzymatic biomarkers in monitoring the pollution in Jeddah red sea shore. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Variola%20louti" title="Variola louti">Variola louti</a>, <a href="https://publications.waset.org/abstracts/search?q=enzymatic%20biomarkers" title=" enzymatic biomarkers"> enzymatic biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=pollution" title=" pollution"> pollution</a>, <a href="https://publications.waset.org/abstracts/search?q=Red%20sea" title=" Red sea"> Red sea</a> </p> <a href="https://publications.waset.org/abstracts/51299/enzymatic-biomonitoring-of-aquatic-pollution-at-jeddah-southern-red-sea-shore" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51299.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">339</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1495</span> Structural and Optical Properties of RF-Sputtered ZnS and Zn(S,O) Thin Films</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ould%20Mohamed%20Cheikh">Ould Mohamed Cheikh</a>, <a href="https://publications.waset.org/abstracts/search?q=Mounir%20Chaik"> Mounir Chaik</a>, <a href="https://publications.waset.org/abstracts/search?q=Hind%20El%20Aakib"> Hind El Aakib</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Aggour"> Mohamed Aggour</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdelkader%20Outzourhit"> Abdelkader Outzourhit</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Zinc sulfide [ZnS] and oxygenated zinc sulfide Zn(O,S) thin films were deposited on glass substrates, by reactive cathodic radio-frequency (RF) sputtering. The substrates power and percentage of oxygen were varied in the range of 100W to 250W and from 5% to 20% respectively. The structural, morphological and optical properties of these thin films were investigated. The optical properties (mainly the refractive index, absorption coefficient and optical band gap) were examined by optical transmission measurements in the ultraviolet-visible-near Infrared wavelength range. XRD analysis indicated that all sputtered ZnS films were a single phase with a preferential orientation along the (111) plane of zinc blend (ZB). The crystallite size was in the range of 19.5 nm to 48.5 nm, the crystallite size varied with RF power reaching a maximum at 200 W. The Zn(O,S) films, on the other hand, were amorphous. UV-Visible, measurements showed that the ZnS film had more than 80% transmittance in the visible wavelength region while that of Zn(O,S is 85%. Moreover, it was observed that the band gap energy of the ZnS films increases slightly from 3.4 to 3.52 eV as the RF power was increased. The optical band gap of Zn(O,S), on the other hand, decreased from 4.2 to 3.89 eV as the oxygen partial pressure is increased in the sputtering atmosphere at a fixed RF-power. Scanning electron microscopy observations revealed smooth surfaces for both type of films. The X-ray reflectometry measurements on the ZnS films showed that the density of the films (3.9 g/cm3) is close that of bulk ZnS. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=thin%20films%20Zn%28O" title="thin films Zn(O">thin films Zn(O</a>, <a href="https://publications.waset.org/abstracts/search?q=S%29%20properties" title="S) properties">S) properties</a>, <a href="https://publications.waset.org/abstracts/search?q=Zn%28O" title=" Zn(O"> Zn(O</a>, <a href="https://publications.waset.org/abstracts/search?q=S%29%20by%20Rf-sputtering" title="S) by Rf-sputtering">S) by Rf-sputtering</a>, <a href="https://publications.waset.org/abstracts/search?q=ZnS%20for%20solar%20cells" title=" ZnS for solar cells"> ZnS for solar cells</a>, <a href="https://publications.waset.org/abstracts/search?q=thin%20films%20for%20renewable%20energy" title=" thin films for renewable energy"> thin films for renewable energy</a> </p> <a href="https://publications.waset.org/abstracts/66128/structural-and-optical-properties-of-rf-sputtered-zns-and-znso-thin-films" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66128.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">282</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1494</span> Green Synthesis of Magnetic, Silica Nanocomposite and Its Adsorptive Performance against Organochlorine Pesticides</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Waleed%20A.%20El-Said">Waleed A. El-Said</a>, <a href="https://publications.waset.org/abstracts/search?q=Dina%20M.%20Fouad"> Dina M. Fouad</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20H.%20Aly"> Mohamed H. Aly</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20El-Gahami"> Mohamed A. El-Gahami</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Green synthesis of nanomaterials has received increasing attention as an eco-friendly technology in materials science. Here, we have used two types of extractions from green tea leaf (i.e. total extraction and tannin extraction) as reducing agents for a rapid, simple and one step synthesis method of mesoporous silica nanoparticles (MSNPs)/iron oxide (Fe3O4) nanocomposite based on deposition of Fe3O4 onto MSNPs. MSNPs/Fe3O4 nanocomposite were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray, vibrating sample magnetometer, N2 adsorption, and high-resolution transmission electron microscopy. The average mesoporous silica particle diameter was found to be around 30 nm with high surface area (818 m2/gm). MSNPs/Fe3O4 nanocomposite was used for removing lindane pesticide (an environmental hazard material) from aqueous solutions. Fourier transform infrared, UV-vis, High-performance liquid chromatography and gas chromatography techniques were used to confirm the high ability of MSNPs/Fe3O4 nanocomposite for sensing and capture of lindane molecules with high sorption capacity (more than 89%) that could develop a new eco-friendly strategy for detection and removing of pesticide and as a promising material for water treatment application. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=green%20synthesis" title="green synthesis">green synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=mesoporous%20silica" title=" mesoporous silica"> mesoporous silica</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20iron%20oxide%20NPs" title=" magnetic iron oxide NPs"> magnetic iron oxide NPs</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption%20Lindane" title=" adsorption Lindane"> adsorption Lindane</a> </p> <a href="https://publications.waset.org/abstracts/74140/green-synthesis-of-magnetic-silica-nanocomposite-and-its-adsorptive-performance-against-organochlorine-pesticides" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74140.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">436</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1493</span> Effect of Manual Progressive Ischemic Pressure versus Post Isometric Facilitation in the Treatment of Latent Myofascial Trigger Points in Mechanical Neck Pain</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20M.%20Diab">Mohamed M. Diab</a>, <a href="https://publications.waset.org/abstracts/search?q=Fahmy%20E.%20Mohamed"> Fahmy E. Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaa%20Balbaa"> Alaa Balbaa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Myofascial pain syndrome a common type of non-articular musculoskeletal pain, is a condition associated with regional pain and muscle tenderness characterized by the presence of hypersensitive nodules. Objectives: the purpose of this study is to compare between the effects of manual progressive ischemic pressure versus the effect of post isometric facilitation in the treatment of Rhomboid latent myofascial trigger points. Methods: six patients had participated in this study. Patients divided into two groups. Group A treated by manual progressive ischemic pressure and traditional physical therapy program. Group B treated by post isometric facilitation and traditional physical therapy program. Treatment program was for 6 sessions over two week’s period. Result: Statistical analysis revealed that there is no significant difference in post treatment from pretreatment in pain severity (VAS) in myofascial trigger points with Rhomboid muscles) and Pain pressure threshold (PPT) for tenderness at both groups (A,B). Conclusion: ischemic pressure technique appear to be no more effective than post isometric facilitation in treatment of rhomboids latent myofacial trigger point. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rhmoiboid%20trigger%20point" title="Rhmoiboid trigger point">Rhmoiboid trigger point</a>, <a href="https://publications.waset.org/abstracts/search?q=myofacila%20trigger%20point" title=" myofacila trigger point"> myofacila trigger point</a>, <a href="https://publications.waset.org/abstracts/search?q=ischemic%20pressure" title=" ischemic pressure"> ischemic pressure</a>, <a href="https://publications.waset.org/abstracts/search?q=post%20isometric%20facilitation" title=" post isometric facilitation"> post isometric facilitation</a> </p> <a href="https://publications.waset.org/abstracts/45700/effect-of-manual-progressive-ischemic-pressure-versus-post-isometric-facilitation-in-the-treatment-of-latent-myofascial-trigger-points-in-mechanical-neck-pain" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45700.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">312</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1492</span> Tribological Behavior of PTFE Composites Used for Guide Rings of Hydraulic Actuating Cylinders under Oil-Lubricated Condition</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Trabelsi%20Mohamed">Trabelsi Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Kharrat%20Mohamed"> Kharrat Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Dammak%20Maher"> Dammak Maher</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Guide rings play an important role in the performance and durability of hydraulic actuating cylinders. In service, guide rings surfaces are subjected to friction and wear against steel counterface. A good mastery of these phenomena is required for the improvement of the energy safeguard and the durability of the actuating cylinder. Polytetrafluoroethylene (PTFE) polymer is extensively used in guide rings thanks to its low coefficient of friction, its good resistance to solvents as well as its high temperature stability. In this study, friction and wear behavior of two PTFE composites filled with bronze and bronze plus MoS2 were evaluated under oil-lubricated condition, aiming as guide rings for hydraulic actuating cylinder. Wear tests of the PTFE composite specimen sliding against steel ball were conducted using reciprocating linear tribometer. The wear mechanisms of the composites under the same sliding condition were discussed, based on Scanning Electron Microscopy examination of the worn composite surface and the optical micrographs of the steel counter surface. As for the results, comparative friction behaviors of the PTFE composites and lower friction coefficients were recorded under oil lubricated condition. The wear behavior was considerably improved to compare with this in dry sliding, while the oil adsorbed layer limited the transfer of the PTFE to the steel counter face during the sliding test. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=PTFE" title="PTFE">PTFE</a>, <a href="https://publications.waset.org/abstracts/search?q=composite" title=" composite"> composite</a>, <a href="https://publications.waset.org/abstracts/search?q=bronze" title=" bronze"> bronze</a>, <a href="https://publications.waset.org/abstracts/search?q=MoS2" title=" MoS2"> MoS2</a>, <a href="https://publications.waset.org/abstracts/search?q=friction" title=" friction"> friction</a>, <a href="https://publications.waset.org/abstracts/search?q=wear" title=" wear"> wear</a>, <a href="https://publications.waset.org/abstracts/search?q=oil-lubrication" title=" oil-lubrication"> oil-lubrication</a> </p> <a href="https://publications.waset.org/abstracts/12663/tribological-behavior-of-ptfe-composites-used-for-guide-rings-of-hydraulic-actuating-cylinders-under-oil-lubricated-condition" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12663.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">299</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1491</span> Overview of the CRM Market in Tunisia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Amine%20Bouraoui">Mohamed Amine Bouraoui</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this paper is to realize the importance of a CRM approach, to detect the degree of awareness of Tunisian managers of this importance and analyse the degree of integration of CRM in the Tunisian companies. Initially, we focus on the definition and components of CRM, then we focus on the level of integration of CRM within Tunisian enterprises. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CRM" title="CRM">CRM</a>, <a href="https://publications.waset.org/abstracts/search?q=operational%20tools" title=" operational tools"> operational tools</a>, <a href="https://publications.waset.org/abstracts/search?q=analytical%20tools" title=" analytical tools"> analytical tools</a>, <a href="https://publications.waset.org/abstracts/search?q=Tunisian%20company" title=" Tunisian company"> Tunisian company</a> </p> <a href="https://publications.waset.org/abstracts/27003/overview-of-the-crm-market-in-tunisia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27003.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">422</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1490</span> Factors Associated with Uptake of Influenza and Pertussis Vaccination in Pregnant Women</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hassen%20Mohammed">Hassen Mohammed</a>, <a href="https://publications.waset.org/abstracts/search?q=Michelle%20Clarke"> Michelle Clarke</a>, <a href="https://publications.waset.org/abstracts/search?q=Helen%20Marshall"> Helen Marshall</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Maternal immunization is an effective strategy to protect pregnant women and their offspring from vaccine-preventable diseases. Despite the recommendation of maternal influenza and more recently pertussis immunization in Australia, uptake of these vaccines has been suboptimal. Monitoring the impact of the current funded vaccine programs for pregnant women is limited. The study aimed to assess the impact of the funded program and determine factors associated with vaccine uptake in pregnant women. This observational prospective study was undertaken between November 2014 and July 2016 at the Women’s and Children’s Hospital in South Australia (WCH). Demographic details and vaccination history from South Australian pregnant women who attended the WCH were reviewed. A standardized self-reported survey was conducted in antenatal care with a follow up telephone interview at 8-10 weeks post-delivery. A midwife delivered immunization program for pregnant women in antenatal clinic commenced in April 2015. Of the 180 pregnant women who completed the survey questionnaire, 75.5% and 80.5 % received maternal influenza and pertussis vaccines respectively. First-time mothers had twice the odds of having received influenza vaccine during pregnancy than multiparous women (OR 2.4; CI 1.14 - 4.94; p= 0.021). The proportion of women who received pertussis vaccine during pregnancy, following the introduction of the midwife delivered pertussis vaccination program (140/155, 90.3%) was significantly higher compared with women who received maternal pertussis vaccination prior to the introduction of the program (5/22, 23.7%, p < 0.001). The odds of women receiving maternal pertussis vaccine following the implementation of the midwife delivered program were 31 times higher than women who delivered babies prior to the program (OR 31.7, CI 10.24- 98.27; p < 0.001). High uptake of influenza and pertussis vaccines during pregnancy can be attained with health care provider recommendation and inclusion of maternal immunization as part of standard antenatal care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=influenza" title="influenza">influenza</a>, <a href="https://publications.waset.org/abstracts/search?q=maternal%20immunization" title=" maternal immunization"> maternal immunization</a>, <a href="https://publications.waset.org/abstracts/search?q=pertussis" title=" pertussis"> pertussis</a>, <a href="https://publications.waset.org/abstracts/search?q=provider%20recommendation" title=" provider recommendation"> provider recommendation</a> </p> <a href="https://publications.waset.org/abstracts/70822/factors-associated-with-uptake-of-influenza-and-pertussis-vaccination-in-pregnant-women" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70822.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1489</span> Organic Geochemical Characterization of the Ordovician Source Rock in the Chotts Basin, Southern Tunisia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anis%20Belhaj%20Mohamed">Anis Belhaj Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Moncef%20Saidi"> Moncef Saidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Soussi"> Mohamed Soussi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20Bouazizi"> Ibrahim Bouazizi</a>, <a href="https://publications.waset.org/abstracts/search?q=Monia%20Ben%20Jrad"> Monia Ben Jrad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper summarizes the results of Rock-Eval pyrolysis and biomarker data of shale samples collected from the Ordovician age (Llanvirnian-Llandeilian) (Azzel Formation) in the Chotts basin southern part of Tunisia. The results are supported by analysis of cutting samples from wells. The Azzel shales has poor to moderate, occasionally good, potential for sourcing oil and gas with Total Organic Carbon (TOC) content varying from 0.80 to 4.49 % and petroleum potential (PP) values varying between 0.68 to 9.20 Kg of HC/t rock in Baguel and Alaguia wells. However, the Azzel Formation show poor to fair TOC and PP in Elfranig and HajBrahim wells not exceeding 1.10% and 1.05 kg HC/t of rock respectively. The Hydrogen Index (HI) and the Oxygen Index (OI) values of 95–165 mg S2/g TOC and of 33–108 mg CO2/g rock relatively show that the Ordovician shales exhibit type II Kerogen that reached the main oil window stage and that the organic matter was bad preserved, Tmax values of 435 – 448°C indicate the organic matter is mature. The biomarker features of the extract samples are characterized by high proportion of tricyclic terpanes that are dominated by C23 and C21 tricyclic terpanes. The hopanes fraction is dominated by C29 and C30 hopanes. The Ordovician shales show a predominance of C27 over C29 steranes (C27/C29>1) and relatively high proportions of diasteranes supporting the shaly character of the source rock. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomarkers" title="biomarkers">biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=organic%20geochemistry" title=" organic geochemistry"> organic geochemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=ordovician%20source%20rock" title=" ordovician source rock"> ordovician source rock</a>, <a href="https://publications.waset.org/abstracts/search?q=diasteranes" title=" diasteranes"> diasteranes</a> </p> <a href="https://publications.waset.org/abstracts/24227/organic-geochemical-characterization-of-the-ordovician-source-rock-in-the-chotts-basin-southern-tunisia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24227.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">505</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1488</span> Interaction of Chemical, Microbiological and Ecological Aspects in the Brown Alga Zonaria Tournefortii</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sonia%20Hamiche">Sonia Hamiche</a>, <a href="https://publications.waset.org/abstracts/search?q=Naima%20Bouzidi"> Naima Bouzidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Reda%20Zahi"> Mohamed Reda Zahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Yasmina%20Daghbouche"> Yasmina Daghbouche</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdelmalek%20Badis"> Abdelmalek Badis</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20El%20Hattab"> Mohamed El Hattab</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study was carried out on the brown alga Zonaria tourfortii harvested on the central coast of Algeria. The chemical study enabled the characterization of phenolic compounds, mainly acyl phloroglucinol and chromone metabolites. The study isolated a significant quantity of all-cis-5,8,11,14,17 eicosapentanoic acid (EPA). Based on a literature review, we have proposed a biosynthetic pathway leading from EPA to phenolic metabolites. Bacterial screening from the algal surface led to isolate 30 bacterial strains, including 26 Gram+ containing the Staphylococcus and Bacillus genus, and 4 Gram- containing the Acinetobacter and Enterobacteracea genus. In terms of activity profiles, strain S13 (identified as Bacillus amyloliquefaciens based on 16S rRNA technique) proved highly interesting inhibitory activities against target germs, as well as its production of diffusible and volatile compounds. Bacterial cells from the B. amyloliquefaciens S13 strain were used to recover a volatile fraction. Analysis was carried out by gas chromatography-mass spectrometry. The main volatile compounds identified were: 13-epi-manoyl oxide (29.39%), manool (17.39%), 15,16-dinorlabd-8(20)-en-13-one (13.17%), labda-8(17),13Z-dien-15-ol (9. 51%) and 3-acetoxy-13 epimanoyl oxide (5.26%) belonging to the labdane class of diterpenes, the latter having never been described in the category of microbial volatile organic compounds. Ecological aspects were discussed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chemical%20analysis" title="chemical analysis">chemical analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=acylphloroglucinols" title=" acylphloroglucinols"> acylphloroglucinols</a>, <a href="https://publications.waset.org/abstracts/search?q=phenolic%20compounds" title=" phenolic compounds"> phenolic compounds</a>, <a href="https://publications.waset.org/abstracts/search?q=microbial%20volatiles" title=" microbial volatiles"> microbial volatiles</a>, <a href="https://publications.waset.org/abstracts/search?q=Zonaria%20tournefortii" title=" Zonaria tournefortii"> Zonaria tournefortii</a> </p> <a href="https://publications.waset.org/abstracts/185772/interaction-of-chemical-microbiological-and-ecological-aspects-in-the-brown-alga-zonaria-tournefortii" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185772.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">60</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1487</span> Anterior Segment Optical Coherence Tomography Study of Cornea and Tear Film Parameters in Juvenile Systemic Lupus Erythematous Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Salah%20El-Din%20Mahmoud">Mohamed Salah El-Din Mahmoud</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Hamed"> Ahmed Hamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Asmaa%20Anwar%20Mohamed"> Asmaa Anwar Mohamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: To study the tear film parameters, total corneal thickness (CT), corneal epithelial thickness and, corneal power in Juvenile systemic lupus erythematosus (JSLE) patients compared to age-matched controls using anterior segment optical coherence tomography (AS-OCT). Methods: This was a cross-sectional study. Study participants were divided into 2 groups: Group A: 75 eyes of JSLE patients, Group B: 75 eyes of healthy controls. Tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA) were the lower tear meniscus parameters that were measured. The corneal power, CT, and epithelial thickness were all determined automatically. Results: In the JSLE group, the range of age was 10 to 15 years while the control group was 11 to 16 years. TMH, TMA, and TMD were 527.7±46.8, 0.059±0.015 and 343.3±59.9 respectively in JSLE group while 525.4±44.6, 0.058±0.011 and 340.6±58.0 respectively in control group without significant difference (p-value<0.001). The corneal power was 43.3±0.55 in the JSLE while 43.2±0.54 in the control group without significant difference (p-value= 0.407). CT was 551.1±13.5 in JSLE group while 551.2±15.3 in control group without significant difference (p-value= 0.982). Epithelial thickness was 52.66±1.35 in the JSLE group while 52.60±1.36 in the control group without significant difference (p-value= 0.765). Conclusion: We demonstrated no significant difference in tear meniscus dimensions, CT, epithelial thickness, and corneal power in the JSLE patients compared to age-matched controls using AS-OCT. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=tear%20film" title="tear film">tear film</a>, <a href="https://publications.waset.org/abstracts/search?q=ASOCT" title=" ASOCT"> ASOCT</a>, <a href="https://publications.waset.org/abstracts/search?q=JSLE" title=" JSLE"> JSLE</a>, <a href="https://publications.waset.org/abstracts/search?q=pachymetry" title=" pachymetry"> pachymetry</a>, <a href="https://publications.waset.org/abstracts/search?q=corneal%20thickness" title=" corneal thickness"> corneal thickness</a> </p> <a href="https://publications.waset.org/abstracts/143829/anterior-segment-optical-coherence-tomography-study-of-cornea-and-tear-film-parameters-in-juvenile-systemic-lupus-erythematous-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143829.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">172</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1486</span> Numerical Investigation of Material Behavior During Non-Equal Channel Multi Angular Extrusion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20S.%20El-Asfoury">Mohamed S. El-Asfoury</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Abdel-Moneim"> Ahmed Abdel-Moneim</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20N.%20A.%20Nasr"> Mohamed N. A. Nasr</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The current study uses finite element modeling to investigate and analyze a modified form of the from the conventional equal channel multi-angular pressing (ECMAP), using non-equal channels, on the workpiece material plastic deformation. The modified process non-equal channel multi-angular extrusion (NECMAE) is modeled using two-dimensional plane strain finite element model built using the commercial software ABAQUS. The workpiece material used is pure aluminum. The model was first validated by comparing its results to analytical solutions for single-pass equal channel angular extrusion (ECAP), as well as previously published data. After that, the model was used to examine the effects of different % of reductions of the area (for the second stage) on material plastic deformation, corner gap, and required the load. Three levels of reduction in the area were modeled; 10%, 30%, and 50%, and compared to single-pass and double-pass ECAP. Cases with a higher reduction in the area were found to have smaller corner gaps, higher and much uniform plastic deformation, as well as higher required loads. The current results are mainly attributed to the back pressure effects exerted by the second stage, as well as strain hardening effects experienced during the first stage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=non-equal%20channel%20angular%20extrusion" title="non-equal channel angular extrusion">non-equal channel angular extrusion</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-pass" title=" multi-pass"> multi-pass</a>, <a href="https://publications.waset.org/abstracts/search?q=sever%20plastic%20deformation" title=" sever plastic deformation"> sever plastic deformation</a>, <a href="https://publications.waset.org/abstracts/search?q=back%20pressure" title=" back pressure"> back pressure</a>, <a href="https://publications.waset.org/abstracts/search?q=Finite%20Element%20Modelling%20%28FEM%29" title=" Finite Element Modelling (FEM)"> Finite Element Modelling (FEM)</a> </p> <a href="https://publications.waset.org/abstracts/15028/numerical-investigation-of-material-behavior-during-non-equal-channel-multi-angular-extrusion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15028.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">422</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1485</span> Epoxomicin Affects Proliferating Neural Progenitor Cells of Rat</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bahaa%20Eldin%20A.%20Fouda">Bahaa Eldin A. Fouda</a>, <a href="https://publications.waset.org/abstracts/search?q=Khaled%20N.%20Yossef"> Khaled N. Yossef</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Elhosseny"> Mohamed Elhosseny</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Lotfy"> Ahmed Lotfy</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Salama"> Mohamed Salama</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Sobh"> Mohamed Sobh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Developmental neurotoxicity (DNT) entails the toxic effects imparted by various chemicals on the brain during the early childhood period. As human brains are vulnerable during this period, various chemicals would have their maximum effects on brains during early childhood. Some toxicants have been confirmed to induce developmental toxic effects on CNS e.g. lead, however; most of the agents cannot be identified with certainty due the defective nature of predictive toxicology models used. A novel alternative method that can overcome most of the limitations of conventional techniques is the use of 3D neurospheres system. This in-vitro system can recapitulate most of the changes during the period of brain development making it an ideal model for predicting neurotoxic effects. In the present study, we verified the possible DNT of epoxomicin which is a naturally occurring selective proteasome inhibitor with anti-inflammatory activity. Rat neural progenitor cells were isolated from rat embryos (E14) extracted from placental tissue. The cortices were aseptically dissected out from the brains of the fetuses and the tissues were triturated by repeated passage through a fire-polished constricted Pasteur pipette. The dispersed tissues were allowed to settle for 3 min. The supernatant was, then, transferred to a fresh tube and centrifuged at 1,000 g for 5 min. The pellet was placed in Hank’s balanced salt solution cultured as free-floating neurospheres in proliferation medium. Two doses of epoxomicin (1µM and 10µM) were used in cultured neuropsheres for a period of 14 days. For proliferation analysis, spheres were cultured in proliferation medium. After 0, 4, 5, 11, and 14 days, sphere size was determined by software analyses. The diameter of each neurosphere was measured and exported to excel file further to statistical analysis. For viability analysis, trypsin-EDTA solution were added to neurospheres for 3 min to dissociate them into single cells suspension, then viability evaluated by the Trypan Blue exclusion test. Epoxomicin was found to affect proliferation and viability of neuropsheres, these effects were positively correlated to doses and progress of time. This study confirms the DNT effects of epoxomicin on 3D neurospheres model. The effects on proliferation suggest possible gross morphologic changes while the decrease in viability propose possible focal lesion on exposure to epoxomicin during early childhood. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=neural%20progentor%20cells" title="neural progentor cells">neural progentor cells</a>, <a href="https://publications.waset.org/abstracts/search?q=epoxomicin" title=" epoxomicin"> epoxomicin</a>, <a href="https://publications.waset.org/abstracts/search?q=neurosphere" title=" neurosphere"> neurosphere</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20and%20health%20sciences" title=" medical and health sciences"> medical and health sciences</a> </p> <a href="https://publications.waset.org/abstracts/15247/epoxomicin-affects-proliferating-neural-progenitor-cells-of-rat" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15247.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">426</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1484</span> An Assessment of Different Blade Tip Timing (BTT) Algorithms Using an Experimentally Validated Finite Element Model Simulator</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Mohamed">Mohamed Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Philip%20Bonello"> Philip Bonello</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Russhard"> Peter Russhard</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Blade Tip Timing (BTT) is a technology concerned with the estimation of both frequency and amplitude of rotating blades. A BTT system comprises two main parts: (a) the arrival time measurement system, and (b) the analysis algorithms. Simulators play an important role in the development of the analysis algorithms since they generate blade tip displacement data from the simulated blade vibration under controlled conditions. This enables an assessment of the performance of the different algorithms with respect to their ability to accurately reproduce the original simulated vibration. Such an assessment is usually not possible with real engine data since there is no practical alternative to BTT for blade vibration measurement. Most simulators used in the literature are based on a simple spring-mass-damper model to determine the vibration. In this work, a more realistic experimentally validated simulator based on the Finite Element (FE) model of a bladed disc (blisk) is first presented. It is then used to generate the necessary data for the assessment of different BTT algorithms. The FE modelling is validated using both a hammer test and two firewire cameras for the mode shapes. A number of autoregressive methods, fitting methods and state-of-the-art inverse methods (i.e. Russhard) are compared. All methods are compared with respect to both synchronous and asynchronous excitations with both single and simultaneous frequencies. The study assesses the applicability of each method for different conditions of vibration, amount of sampling data, and testing facilities, according to its performance and efficiency under these conditions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blade%20tip%20timing" title="blade tip timing">blade tip timing</a>, <a href="https://publications.waset.org/abstracts/search?q=blisk" title=" blisk"> blisk</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element" title=" finite element"> finite element</a>, <a href="https://publications.waset.org/abstracts/search?q=vibration%20measurement" title=" vibration measurement"> vibration measurement</a> </p> <a href="https://publications.waset.org/abstracts/59842/an-assessment-of-different-blade-tip-timing-btt-algorithms-using-an-experimentally-validated-finite-element-model-simulator" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59842.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">310</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1483</span> Carotid Intima-Media Thickness and Ankle-Brachial Index as Predictors of the Severity of Coronary Artery Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ali%20Kassem">Ali Kassem</a>, <a href="https://publications.waset.org/abstracts/search?q=Yaser%20Kamal"> Yaser Kamal</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Abdel%20Wahab"> Mohamed Abdel Wahab</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Hussen"> Mohamed Hussen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Atherosclerosis is one of the leading causes of death all over the world. Recently, there is an increasing interest in Carotid Intima-Medial Thickness (CIMT) and Ankle Brachial Index (ABI) as non-invasive tools for identifying subclinical atherosclerosis. We aim to examine the role of CIMT and ABI as predictors of the severity of angiographically documented coronary artery disease (CAD). Methods: A cross-sectional study conducted on 60 patients who were investigated by coronary angiography at Sohag University Hospital, Egypt. CIMT: After the carotid arteries were located by transverse scans, the probe was rotated 90 ° to obtain and record longitudinal images of bilateral carotid arteries ABI: Each patient was evaluated in the supine position after resting for 5 min. ABI was measured in each leg using a Doppler Ultrasound while the patient remained in the same position. The lowest ABI obtained for either leg was taken as the ABI measurement for the patient. Results: Patients with carotid mean IMT ≥ 0.9 mm had significantly more severe coronary artery disease than patients without thickening (mean IMT > 0.9 mm). Similarly, patients with low ABI (< 0.9) had significantly more severe coronary artery disease than patients with ABI ≥ 0.9. When the patients were divided into 4 groups (group A, n = 15, mean IMT < 0.9 mm, ABI ≥ 0.9; group B, n = 25, mean IMT < 0.9 mm, low ABI; group C, n = 5, mean IMT ≥ 0.9 mm, ABI ≥ 0.9; group D, n = 19, mean IMT ≤ 0.9 mm, low ABI), the presence of significant coronary stenosis (> 50%) of the groups were significantly different (group A, n = 5: (33.3%); group B, n = 11: (52.4%); group C, n = 4: (60%); group D, n=15, (78.9%), P = 0.001). Conclusion: CIMT and ABI provide useful information on the severity of CAD. Early and aggressive intervention should be considered in patients with CAD and abnormalities in one or both of these non-invasive modalities. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ankle%20brachial%20index" title="ankle brachial index">ankle brachial index</a>, <a href="https://publications.waset.org/abstracts/search?q=carotid%20intima%20media%20thickness" title=" carotid intima media thickness"> carotid intima media thickness</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20artery%20disease" title=" coronary artery disease"> coronary artery disease</a>, <a href="https://publications.waset.org/abstracts/search?q=predictors%20of%20severity" title=" predictors of severity"> predictors of severity</a> </p> <a href="https://publications.waset.org/abstracts/94691/carotid-intima-media-thickness-and-ankle-brachial-index-as-predictors-of-the-severity-of-coronary-artery-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/94691.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">232</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1482</span> Culturable Diversity of Halophilic Bacteria in Chott Tinsilt, Algeria </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nesrine%20Lenchi">Nesrine Lenchi</a>, <a href="https://publications.waset.org/abstracts/search?q=Salima%20Kebbouche-Gana"> Salima Kebbouche-Gana</a>, <a href="https://publications.waset.org/abstracts/search?q=Laddada%20Belaid"> Laddada Belaid</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Lamine%20Khelfaoui"> Mohamed Lamine Khelfaoui</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Lamine%20Gana"> Mohamed Lamine Gana </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Saline lakes are extreme hypersaline environments that are considered five to ten times saltier than seawater (150 – 300 g L-1 salt concentration). Hypersaline regions differ from each other in terms of salt concentration, chemical composition and geographical location, which determine the nature of inhabitant microorganisms. In order to explore the diversity of moderate and extreme halophiles Bacteria in Chott Tinsilt (East of Algeria), an isolation program was performed. In the first time, water samples were collected from the saltern during pre-salt harvesting phase. Salinity, pH and temperature of the sampling site were determined in situ. Chemical analysis of water sample indicated that Na +and Cl- were the most abundant ions. Isolates were obtained by plating out the samples in complex and synthetic media. In this study, seven halophiles cultures of Bacteria were isolated. Isolates were studied for Gram’s reaction, cell morphology and pigmentation. Enzymatic assays (oxidase, catalase, nitrate reductase and urease), and optimization of growth conditions were done. The results indicated that the salinity optima varied from 50 to 250 g L-1, whereas the optimum of temperature range from 25°C to 35°C. Molecular identification of the isolates was performed by sequencing the 16S rRNA gene. The results showed that these cultured isolates included members belonging to the Halomonas, Staphylococcus, Salinivibrio, Idiomarina, Halobacillus Thalassobacillus and Planococcus genera and what may represent a new bacterial genus. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bacteria" title="bacteria">bacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=Chott" title=" Chott"> Chott</a>, <a href="https://publications.waset.org/abstracts/search?q=halophilic" title=" halophilic"> halophilic</a>, <a href="https://publications.waset.org/abstracts/search?q=16S%20rRNA" title=" 16S rRNA"> 16S rRNA</a> </p> <a href="https://publications.waset.org/abstracts/47059/culturable-diversity-of-halophilic-bacteria-in-chott-tinsilt-algeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47059.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">281</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1481</span> Approximation of a Wanted Flow via Topological Sensitivity Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Abdelwahed">Mohamed Abdelwahed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We propose an optimization algorithm for the geometric control of fluid flow. The used approach is based on the topological sensitivity analysis method. It consists in studying the variation of a cost function with respect to the insertion of a small obstacle in the domain. Some theoretical and numerical results are presented in 2D and 3D. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sensitivity%20analysis" title="sensitivity analysis">sensitivity analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=topological%20gradient" title=" topological gradient"> topological gradient</a>, <a href="https://publications.waset.org/abstracts/search?q=shape%20optimization" title=" shape optimization"> shape optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=stokes%20equations" title=" stokes equations"> stokes equations</a> </p> <a href="https://publications.waset.org/abstracts/3510/approximation-of-a-wanted-flow-via-topological-sensitivity-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3510.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">537</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1480</span> Imputation of Incomplete Large-Scale Monitoring Count Data via Penalized Estimation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20%20Dakki">Mohamed Dakki</a>, <a href="https://publications.waset.org/abstracts/search?q=Genevieve%20Robin"> Genevieve Robin</a>, <a href="https://publications.waset.org/abstracts/search?q=Marie%20Suet"> Marie Suet</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdeljebbar%20Qninba"> Abdeljebbar Qninba</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20El%20Agbani"> Mohamed A. El Agbani</a>, <a href="https://publications.waset.org/abstracts/search?q=Asm%C3%A2a%20%20Ouassou"> Asmâa Ouassou</a>, <a href="https://publications.waset.org/abstracts/search?q=Rhimou%20El%20Hamoumi"> Rhimou El Hamoumi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hichem%20Azafzaf"> Hichem Azafzaf</a>, <a href="https://publications.waset.org/abstracts/search?q=Sami%20Rebah"> Sami Rebah</a>, <a href="https://publications.waset.org/abstracts/search?q=Claudia%20Feltrup-Azafzaf"> Claudia Feltrup-Azafzaf</a>, <a href="https://publications.waset.org/abstracts/search?q=Nafouel%20%20Hamouda"> Nafouel Hamouda</a>, <a href="https://publications.waset.org/abstracts/search?q=Wed%20a.L.%20Ibrahim"> Wed a.L. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hosni%20H.%20%20Asran"> Hosni H. Asran</a>, <a href="https://publications.waset.org/abstracts/search?q=Amr%20A.%20%20Elhady"> Amr A. Elhady</a>, <a href="https://publications.waset.org/abstracts/search?q=Haitham%20Ibrahim"> Haitham Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Khaled%20Etayeb"> Khaled Etayeb</a>, <a href="https://publications.waset.org/abstracts/search?q=Essam%20Bouras"> Essam Bouras</a>, <a href="https://publications.waset.org/abstracts/search?q=Almokhtar%20Saied"> Almokhtar Saied</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashrof%20Glidan"> Ashrof Glidan</a>, <a href="https://publications.waset.org/abstracts/search?q=Bakar%20M.%20Habib"> Bakar M. Habib</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20S.%20Sayoud"> Mohamed S. Sayoud</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadjiba%20Bendjedda"> Nadjiba Bendjedda</a>, <a href="https://publications.waset.org/abstracts/search?q=Laura%20Dami"> Laura Dami</a>, <a href="https://publications.waset.org/abstracts/search?q=Clemence%20Deschamps"> Clemence Deschamps</a>, <a href="https://publications.waset.org/abstracts/search?q=Elie%20Gaget"> Elie Gaget</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Yves%20Mondain-Monval"> Jean-Yves Mondain-Monval</a>, <a href="https://publications.waset.org/abstracts/search?q=Pierre%20Defos%20Du%20Rau"> Pierre Defos Du Rau</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In biodiversity monitoring, large datasets are becoming more and more widely available and are increasingly used globally to estimate species trends and con- servation status. These large-scale datasets challenge existing statistical analysis methods, many of which are not adapted to their size, incompleteness and heterogeneity. The development of scalable methods to impute missing data in incomplete large-scale monitoring datasets is crucial to balance sampling in time or space and thus better inform conservation policies. We developed a new method based on penalized Poisson models to impute and analyse incomplete monitoring data in a large-scale framework. The method al- lows parameterization of (a) space and time factors, (b) the main effects of predic- tor covariates, as well as (c) space–time interactions. It also benefits from robust statistical and computational capability in large-scale settings. The method was tested extensively on both simulated and real-life waterbird data, with the findings revealing that it outperforms six existing methods in terms of missing data imputation errors. Applying the method to 16 waterbird species, we estimated their long-term trends for the first time at the entire North African scale, a region where monitoring data suffer from many gaps in space and time series. This new approach opens promising perspectives to increase the accuracy of species-abundance trend estimations. We made it freely available in the r package ‘lori’ (https://CRAN.R-project.org/package=lori) and recommend its use for large- scale count data, particularly in citizen science monitoring programmes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biodiversity%20monitoring" title="biodiversity monitoring">biodiversity monitoring</a>, <a href="https://publications.waset.org/abstracts/search?q=high-dimensional%20statistics" title=" high-dimensional statistics"> high-dimensional statistics</a>, <a href="https://publications.waset.org/abstracts/search?q=incomplete%20count%20data" title=" incomplete count data"> incomplete count data</a>, <a href="https://publications.waset.org/abstracts/search?q=missing%20data%20imputation" title=" missing data imputation"> missing data imputation</a>, <a href="https://publications.waset.org/abstracts/search?q=waterbird%20trends%20in%20North-Africa" title=" waterbird trends in North-Africa"> waterbird trends in North-Africa</a> </p> <a href="https://publications.waset.org/abstracts/137277/imputation-of-incomplete-large-scale-monitoring-count-data-via-penalized-estimation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137277.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">156</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1479</span> The Global Relationship between the Prevalence of Diabetes Mellitus and Incidence of Tuberculosis: 2000-2012 </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alaa%20Badawi">Alaa Badawi</a>, <a href="https://publications.waset.org/abstracts/search?q=Suzan%20Sayegh"> Suzan Sayegh</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Sallam"> Mohamed Sallam</a>, <a href="https://publications.waset.org/abstracts/search?q=Eman%20Sadoun"> Eman Sadoun</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Al-Thani"> Mohamed Al-Thani</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20W.%20Alam"> Muhammad W. Alam</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20Arora"> Paul Arora</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The dual burden of tuberculosis (TB) and diabetes mellitus (DM) has increased over the past decade with DM prevalence increasing in countries already afflicted with a high burden of TB. The coexistence of the two conditions presents a serious threat to global public health. Objective: The present study examines the global relationship between the prevalence of DM and the incidence of TB to evaluate their coexistence worldwide and their contribution to one another. Methods: This is an ecological longitudinal study covering the period between years 2000 to 2012. We utilized data from the WHO and World Bank sources and International Diabetes Federation to estimate prevalence of DM (%) and the incidence of TB (per 100,000). Measures of central tendency and dispersion as well as the harmonic mean and linear regression were used for different WHO regions. The association between DM prevalence and TB incidence was examined by quartile of DM prevalence. Results: The worldwide average (±S.D.) prevalence of DM within the study period was 6.6±3.8% whereas TB incidence was 135.0±190.5 per 100,000. DM prevalence was highest in the Eastern Mediterranean (8.3±4.1) and West Pacific (8.2±5.6) regions and lowest in the Africa (3.5±2.6). TB incidence was highest in Africa (313.1±275.9 per 100,000) and South-East Asia (216.7±124.9) and lowest in the European (46.5±68.6) and American (47.2±52.9) regions. Only countries with high DM prevalence (>7.6%) showed a significant positive association with TB incidence (r=0.17, p=0.013). Conclusion: A positive association between DM and TB may exist in some – but not all – world regions, a dual burden that necessitates identifying the nature of this coexistence to assist in developing public health approaches that curb their rising burden. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title="diabetes mellitus">diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title=" tuberculosis"> tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=disease%20burden" title=" disease burden"> disease burden</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20association" title=" global association"> global association</a> </p> <a href="https://publications.waset.org/abstracts/19993/the-global-relationship-between-the-prevalence-of-diabetes-mellitus-and-incidence-of-tuberculosis-2000-2012" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19993.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">466</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1478</span> A Retrospective Study on the Age of Onset for Type 2 Diabetes Diagnosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20Hammad">Mohamed A. Hammad</a>, <a href="https://publications.waset.org/abstracts/search?q=Dzul%20Azri%20Mohamed%20Noor"> Dzul Azri Mohamed Noor</a>, <a href="https://publications.waset.org/abstracts/search?q=Syed%20Azhar%20Syed%20Sulaiman"> Syed Azhar Syed Sulaiman</a>, <a href="https://publications.waset.org/abstracts/search?q=Majed%20Ahmed%20Al-Mansoub"> Majed Ahmed Al-Mansoub</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Qamar"> Muhammad Qamar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There is a progressive increase in the prevalence of early onset Type 2 diabetes mellitus. Early detection of Type 2 diabetes enhances the length and/or quality of life which might result from a reduction in the severity, frequency or prevent or delay of its long-term complications. The study aims to determine the onset age for the first diagnosis of Type 2 diabetes mellitus. A retrospective study conducted in the endocrine clinic at Hospital Pulau Pinang in Penang, Malaysia, January- December 2016. Records of 519 patients with Type 2 diabetes mellitus were screened to collect demographic data and determine the age of first-time diabetes mellitus diagnosis. Patients classified according to the age of diagnosis, gender, and ethnicity. The study included 519 patients with age (55.6±13.7) years, female 265 (51.1%) and male 254 (48.9%). The ethnicity distribution was Malay 191 (36.8%), Chinese 189 (36.4%) and Indian 139 (26.8%). The age of Type 2 diabetes diagnosis was (42±14.8) years. The female onset of diabetes mellitus was at age (41.5±13.7) years, while male (42.6±13.7) years. Distribution of diabetic onset by ethnicity was Malay at age (40.7±13.7) years, Chinese (43.2±13.7) years and Indian (42.3±13.7) years. Diabetic onset was classified by age as follow; ≤20 years’ cohort was 33 (6.4%) cases. Group >20- ≤40 years was 190 (36.6%) patients, and category >40- ≤60 years was 270 (52%) subjects. On the other hand, the group >60 years was 22 (4.2%) patients. The range of diagnosis was between 10 and 73 years old. Conclusion: Malay and female have an earlier onset of diabetes than Indian, Chinese and male. More than half of the patients had diabetes between 40 and 60 years old. Diabetes mellitus is becoming more common in younger age <40 years. The age at diagnosis of Type 2 diabetes mellitus has decreased with time. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=age%20of%20onset" title="age of onset">age of onset</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20diagnosis" title=" diabetes diagnosis"> diabetes diagnosis</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title=" diabetes mellitus"> diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=Malaysia" title=" Malaysia"> Malaysia</a>, <a href="https://publications.waset.org/abstracts/search?q=outpatients" title=" outpatients"> outpatients</a>, <a href="https://publications.waset.org/abstracts/search?q=type%202%20diabetes" title=" type 2 diabetes"> type 2 diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=retrospective%20study" title=" retrospective study"> retrospective study</a> </p> <a href="https://publications.waset.org/abstracts/74920/a-retrospective-study-on-the-age-of-onset-for-type-2-diabetes-diagnosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74920.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">414</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1477</span> The Influence of Salt Body of J. Ech Cheid on the Maturity History of the Cenomanian: Turonian Source Rock</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Malek%20Khenissi">Mohamed Malek Khenissi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Montassar%20Ben%20Slama"> Mohamed Montassar Ben Slama</a>, <a href="https://publications.waset.org/abstracts/search?q=Anis%20Belhaj%20Mohamed"> Anis Belhaj Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Moncef%20Saidi"> Moncef Saidi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Northern Tunisia is well known by its different and complex structural and geological zones that have been the result of a geodynamic history that extends from the early Mesozoic era to the actual period. One of these zones is the salt province, where the Halokinesis process is manifested by a number of NE/SW salt structures such as Jebel Ech-Cheid which represents masses of materials characterized by a high plasticity and low density. The salt masses extrusions that have been developed due to an extension that started from the late Triassic to late Cretaceous. The evolution of salt bodies within sedimentary basins have not only contributed to modify the architecture of the basin, but it also has certain geochemical effects which touch mainly source rocks that surround it. It has been demonstrated that the presence of salt structures within sedimentary basins can influence its temperature distribution and thermal history. Moreover, it has been creating heat flux anomalies that may affect the maturity of organic matter and the timing of hydrocarbon generation. Field samples of the Bahloul source rock (Cenomanan-Tunonian) were collected from different sights from all around Ech Cheid salt structure and evaluated using Rock-eval pyrolysis and GC/MS techniques in order to assess the degree of maturity evolution and the heat flux anomalies in the different zones analyze. The Total organic Carbon (TOC) values range between 1 to 9% and the (Tmax) ranges between 424 and 445°C, also the distribution of the source rock biomarkers both saturated and aromatic changes in a regular fashions with increasing maturity and this are shown in the chromatography results such as Ts/(Ts+Tm) ratios, 22S/(22S+22R) values for C31 homohopanes, ββ/(ββ+αα)20R and 20S/(20S+20R) ratios for C29 steranes which gives a consistent maturity indications and assessment of the field samples. These analyses are carried to interpret the maturity evolution and the heat flux around Ech Cheid salt structure through the geological history. These analyses also aim to demonstrate that the salt structure can have a direct effect on the geothermal gradient of the basin and on the maturity of the Bahloul Formation source rock. The organic matter has reached different stages of thermal maturity, but delineate a general increasing maturity trend. Our study confirms that the J. Ech Cheid salt body have on the first hand: a huge influence on the local distribution of anoxic depocentre at least within Cenomanian-Turonian time. In the second hand, the thermal anomaly near the salt mass has affected the maturity of Bahloul Formation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bahloul%20formation" title="Bahloul formation">Bahloul formation</a>, <a href="https://publications.waset.org/abstracts/search?q=depocentre" title=" depocentre"> depocentre</a>, <a href="https://publications.waset.org/abstracts/search?q=GC%2FMS" title=" GC/MS"> GC/MS</a>, <a href="https://publications.waset.org/abstracts/search?q=rock-eval" title=" rock-eval"> rock-eval</a> </p> <a href="https://publications.waset.org/abstracts/70449/the-influence-of-salt-body-of-j-ech-cheid-on-the-maturity-history-of-the-cenomanian-turonian-source-rock" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70449.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">239</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1476</span> Relation between Chronic Mechanical Low Back Pain and Hip Rotation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20M.%20Diab">Mohamed M. Diab</a>, <a href="https://publications.waset.org/abstracts/search?q=Koura%20G.%20Mohamed"> Koura G. Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Balbaa"> A. Balbaa</a>, <a href="https://publications.waset.org/abstracts/search?q=Radwan%20Sh.%20Ahamed"> Radwan Sh. Ahamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Chronic mechanical low back pain (CMLBP) is the most common complaint of the working-age population. Mechanical low back pain is often a chronic, dull, aching pain of varying intensity that affects the lower spine. In the current proposal the hip rotation-CMLBP relationship is based on that limited hip motion will be compensated by motion in the lumbopelvic region and this increase force translates to the lumbar spine. The purpose of this study was to investigate if there a relationship between chronic mechanical low back pain (CMLBP) and hip medial and lateral rotation (peak torque and Range of motion (ROM) in patients with CMLBP. Methods: Sixty patients with CMLBP diagnosed by an orthopedist participated in the current study after signing a consent form. Their mean of age was (23.76±2.39) years, mean of weight (71.8±12.7) (Kg), mean of height (169.65±7.49) (Cm) and mean of BMI (25.5±3.86) (Kg/m2). Visual Analogue Scale (VAS) was used to assess pain. Fluid Filled Inclinometer was used to measure Hip rotation ROM (medial and lateral). Isokinetic Dynamometer was used to measure peak torque of hip rotators muscles (medial and lateral), concentric peak torque with tow Isokinetic speeds (60ᵒ/sec and 180ᵒ/sec) was selected to measure peak torque. Results: The results of this study demonstrated that there is poor relationship between pain and hip external rotation ROM, also there is poor relation between pain and hip internal rotation ROM. There is poor relation between pain and hip internal rotators peak torque and hip external rotators peak torque in both speeds. Conclusion: Depending on the current study it is not recommended to give an importance to hip rotation in treating Chronic Mechanical Low Back Pain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hip%20rotation%20ROM" title="hip rotation ROM">hip rotation ROM</a>, <a href="https://publications.waset.org/abstracts/search?q=hip%20rotators%20strength" title=" hip rotators strength"> hip rotators strength</a>, <a href="https://publications.waset.org/abstracts/search?q=low%20back%20pain" title=" low back pain"> low back pain</a>, <a href="https://publications.waset.org/abstracts/search?q=chronic%20mechanical" title=" chronic mechanical"> chronic mechanical</a> </p> <a href="https://publications.waset.org/abstracts/23698/relation-between-chronic-mechanical-low-back-pain-and-hip-rotation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23698.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">311</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1475</span> Enhancement of 2, 4-Dichlorophenoxyacetic Acid Solubility via Solid Dispersion Technique</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tamer%20M.%20Shehata">Tamer M. Shehata</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20S.%20Elsewedy"> Heba S. Elsewedy</a>, <a href="https://publications.waset.org/abstracts/search?q=Mashel%20Al%20Dosary"> Mashel Al Dosary</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaa%20Elshehry"> Alaa Elshehry</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20Khedr"> Mohamed A. Khedr</a>, <a href="https://publications.waset.org/abstracts/search?q=Maged%20E.%20Mohamed"> Maged E. Mohamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: 2,4-Dichlorophenoxy acetic acid (2,4-D) is a well-known herbicide widely used as a weed killer. Recently, 2,4-D was rediscovered as a new anti-inflammatory agent through in silico as well as in-vivo experiments. However, poor solubility of 2,4-D could represent a problems during pharmaceutical development in addition to lower bioavailability. Solid dispersion (SD) refers to a group of solid products consisting of at least two different components, usually a hydrophobic drug and hydrophilic matrix. It is well known technique for enhancing drug solubility. Therefore, selecting SD as a tool for enhancing 2,4-D could be of great interest to the formulator. Method: In our project, several polymers were investigated (such as PEG, HPMC, citric acid and others) in addition to drug polymer ratios and its effect on solubility. Evaluation of drug polymer interaction was investigated through both Fourier Transform Infrared (FTIR) and Differential Scanning Calorimetry (DSC). Finally, in-vivo evaluation was performed for the best selected preparation through inflammatory response of rat induce hind paw. Results: Results indicated that, citric acid 2,4-D and in ratio of 0.75 : 1 showed modified the dissolution profile of the drug. The FTIR resltes indicated no significant chemical interaction, however DSC showed shifting of the drug melting point. Finally, Carragenan induced rat hind paw edema showed significant reduction of the drug solid dispersion in comparison to the pure drug, indicating rapid and complete absorption of the drug in solid dispersion form. Conclusion: Solid dispersion technology can be utilized efficiently to enhance the solubility of 2,4-D. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=solid%20dispersion" title="solid dispersion">solid dispersion</a>, <a href="https://publications.waset.org/abstracts/search?q=2" title=" 2"> 2</a>, <a href="https://publications.waset.org/abstracts/search?q=4-D%20solubility" title="4-D solubility">4-D solubility</a>, <a href="https://publications.waset.org/abstracts/search?q=carragenan%20induced%20edema" title=" carragenan induced edema"> carragenan induced edema</a> </p> <a href="https://publications.waset.org/abstracts/41335/enhancement-of-2-4-dichlorophenoxyacetic-acid-solubility-via-solid-dispersion-technique" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41335.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right 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