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aims were to determine whether mild therapeutic hypothermia (MTH) is associated with ECG changes similar to those observed in accidental hypothermia, and to use advanced ECG parameters to further characterize any electrophysiological... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_74220462" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Our aims were to determine whether mild therapeutic hypothermia (MTH) is associated with ECG changes similar to those observed in accidental hypothermia, and to use advanced ECG parameters to further characterize any electrophysiological changes associated with MTH.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/74220462" 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economy","url":"https://www.academia.edu/Documents/in/Running_the_economy?f_ri=71469"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=71469"},{"id":1010596,"name":"Energy Cost","url":"https://www.academia.edu/Documents/in/Energy_Cost?f_ri=71469"},{"id":1145265,"name":"Knee Joint","url":"https://www.academia.edu/Documents/in/Knee_Joint?f_ri=71469"},{"id":1193624,"name":"Oxygen Consumption","url":"https://www.academia.edu/Documents/in/Oxygen_Consumption?f_ri=71469"},{"id":1300379,"name":"Muscle Activity","url":"https://www.academia.edu/Documents/in/Muscle_Activity?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33316845" data-work_id="33316845" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33316845/Exercise_induced_cramp_myoglobinuria_and_tubular_aggregates_in_phosphoglycerate_mutase_deficiency">Exercise-induced cramp, myoglobinuria, and tubular aggregates in phosphoglycerate mutase deficiency</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We report two patients in whom phosphoglycerate mutase (PGAM) deficiency was associated with the triad of exercise-induced cramps, recurrent myoglobinuria, and tubular aggregates in the muscle biopsy. Serum creatine kinase (CK) levels... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_33316845" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We report two patients in whom phosphoglycerate mutase (PGAM) deficiency was associated with the triad of exercise-induced cramps, recurrent myoglobinuria, and tubular aggregates in the muscle biopsy. Serum creatine kinase (CK) levels were elevated between attacks of myoglobinuria. Forearm ischemic exercise tests produced subnormal increases of venous lactate. Muscle biopsies showed subsarcolemmal tubular aggregates in type 2 fibers. Muscle PGAM activities were markedly decreased (3% of the normal mean) and molecular genetic studies showed that both patients were homozygous for a described missense mutation (W78X). A review of 15 cases with tubular aggregates in the muscle biopsies from our laboratory and 15 cases with PGAM deficiency described in the literature showed that this clinicopathological triad is highly suggestive of PGAM deficiency.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33316845" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="240aa159ae296ab8742a0e160aef3f3d" rel="nofollow" data-download="{"attachment_id":53379558,"asset_id":33316845,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53379558/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="65062648" href="https://columbia.academia.edu/ANaini">Ali Naini</a><script data-card-contents-for-user="65062648" type="text/json">{"id":65062648,"first_name":"Ali","last_name":"Naini","domain_name":"columbia","page_name":"ANaini","display_name":"Ali Naini","profile_url":"https://columbia.academia.edu/ANaini?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_33316845 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33316845"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33316845, container: ".js-paper-rank-work_33316845", }); 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$(".js-view-count[data-work-id=33316845]").text(description); $(".js-view-count-work_33316845").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33316845").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33316845"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37826" rel="nofollow" href="https://www.academia.edu/Documents/in/Biopsy">Biopsy</a>, <script data-card-contents-for-ri="37826" type="text/json">{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a><script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33316845]'), work: {"id":33316845,"title":"Exercise-induced cramp, myoglobinuria, and tubular aggregates in phosphoglycerate mutase deficiency","created_at":"2017-06-03T14:28:05.633-07:00","url":"https://www.academia.edu/33316845/Exercise_induced_cramp_myoglobinuria_and_tubular_aggregates_in_phosphoglycerate_mutase_deficiency?f_ri=71469","dom_id":"work_33316845","summary":"We report two patients in whom phosphoglycerate mutase (PGAM) deficiency was associated with the triad of exercise-induced cramps, recurrent myoglobinuria, and tubular aggregates in the muscle biopsy. Serum creatine kinase (CK) levels were elevated between attacks of myoglobinuria. Forearm ischemic exercise tests produced subnormal increases of venous lactate. Muscle biopsies showed subsarcolemmal tubular aggregates in type 2 fibers. Muscle PGAM activities were markedly decreased (3% of the normal mean) and molecular genetic studies showed that both patients were homozygous for a described missense mutation (W78X). A review of 15 cases with tubular aggregates in the muscle biopsies from our laboratory and 15 cases with PGAM deficiency described in the literature showed that this clinicopathological triad is highly suggestive of PGAM deficiency.","downloadable_attachments":[{"id":53379558,"asset_id":33316845,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":65062648,"first_name":"Ali","last_name":"Naini","domain_name":"columbia","page_name":"ANaini","display_name":"Ali Naini","profile_url":"https://columbia.academia.edu/ANaini?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":82983,"name":"Ischemia","url":"https://www.academia.edu/Documents/in/Ischemia?f_ri=71469"},{"id":204436,"name":"Creatine Kinase","url":"https://www.academia.edu/Documents/in/Creatine_Kinase?f_ri=71469"},{"id":233800,"name":"African Americans","url":"https://www.academia.edu/Documents/in/African_Americans?f_ri=71469"},{"id":284067,"name":"Inclusion Bodies","url":"https://www.academia.edu/Documents/in/Inclusion_Bodies?f_ri=71469"},{"id":1146831,"name":"Exercise Test","url":"https://www.academia.edu/Documents/in/Exercise_Test?f_ri=71469"},{"id":1210716,"name":"Exercise Tolerance","url":"https://www.academia.edu/Documents/in/Exercise_Tolerance?f_ri=71469"},{"id":2350842,"name":"Sarcoplasmic reticulum","url":"https://www.academia.edu/Documents/in/Sarcoplasmic_reticulum?f_ri=71469"},{"id":2482159,"name":"DNA mutational analysis","url":"https://www.academia.edu/Documents/in/DNA_mutational_analysis?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13615616" data-work_id="13615616" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13615616/An_anatomically_based_mathematical_model_of_the_gastroesophageal_junction">An anatomically based mathematical model of the gastroesophageal junction</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this study the construction of an initial three-dimensional anatomically based mathematical model of the esophagus is presented. The aim of this model is to provide a framework with which to examine the functional behavior of the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13615616" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this study the construction of an initial three-dimensional anatomically based mathematical model of the esophagus is presented. The aim of this model is to provide a framework with which to examine the functional behavior of the esophagus and the lower esophageal sphincter during swallowing. Anatomical data from the Visible Human Project was used to provide the outlines of the regions of interest. A C/sup 1/ continuous cubic Hermite finite element mesh was then created using an iterative finite element linear fitting process to an RMS error less than 1 mm. Muscular fiber information was embedded within the model using data from published literature. There is a current lack of detailed microstructural data on the gastroesophageal junction. We describe the specialist measurement rig that we propose to use to obtain the microstructural information in our experimental studies.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13615616" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="55b26602b689f92de8c85c473a4ff3a8" rel="nofollow" data-download="{"attachment_id":45152400,"asset_id":13615616,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45152400/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32785659" href="https://auckland.academia.edu/NicolasSmith">Nicolas Smith</a><script data-card-contents-for-user="32785659" type="text/json">{"id":32785659,"first_name":"Nicolas","last_name":"Smith","domain_name":"auckland","page_name":"NicolasSmith","display_name":"Nicolas Smith","profile_url":"https://auckland.academia.edu/NicolasSmith?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13615616 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13615616"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13615616, container: ".js-paper-rank-work_13615616", }); 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$(".js-view-count[data-work-id=13615616]").text(description); $(".js-view-count-work_13615616").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13615616").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13615616"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="5057" rel="nofollow" href="https://www.academia.edu/Documents/in/Iterative_Methods">Iterative Methods</a>, <script data-card-contents-for-ri="5057" type="text/json">{"id":5057,"name":"Iterative Methods","url":"https://www.academia.edu/Documents/in/Iterative_Methods?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8252" rel="nofollow" href="https://www.academia.edu/Documents/in/Mesh_generation">Mesh generation</a>, <script data-card-contents-for-ri="8252" type="text/json">{"id":8252,"name":"Mesh generation","url":"https://www.academia.edu/Documents/in/Mesh_generation?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23042" rel="nofollow" href="https://www.academia.edu/Documents/in/Finite_Element">Finite Element</a>, <script data-card-contents-for-ri="23042" type="text/json">{"id":23042,"name":"Finite Element","url":"https://www.academia.edu/Documents/in/Finite_Element?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a><script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13615616]'), work: {"id":13615616,"title":"An anatomically based mathematical model of the gastroesophageal junction","created_at":"2015-07-04T06:13:50.820-07:00","url":"https://www.academia.edu/13615616/An_anatomically_based_mathematical_model_of_the_gastroesophageal_junction?f_ri=71469","dom_id":"work_13615616","summary":"In this study the construction of an initial three-dimensional anatomically based mathematical model of the esophagus is presented. The aim of this model is to provide a framework with which to examine the functional behavior of the esophagus and the lower esophageal sphincter during swallowing. Anatomical data from the Visible Human Project was used to provide the outlines of the regions of interest. A C/sup 1/ continuous cubic Hermite finite element mesh was then created using an iterative finite element linear fitting process to an RMS error less than 1 mm. Muscular fiber information was embedded within the model using data from published literature. There is a current lack of detailed microstructural data on the gastroesophageal junction. We describe the specialist measurement rig that we propose to use to obtain the microstructural information in our experimental studies.","downloadable_attachments":[{"id":45152400,"asset_id":13615616,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32785659,"first_name":"Nicolas","last_name":"Smith","domain_name":"auckland","page_name":"NicolasSmith","display_name":"Nicolas Smith","profile_url":"https://auckland.academia.edu/NicolasSmith?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":5057,"name":"Iterative Methods","url":"https://www.academia.edu/Documents/in/Iterative_Methods?f_ri=71469","nofollow":true},{"id":8252,"name":"Mesh generation","url":"https://www.academia.edu/Documents/in/Mesh_generation?f_ri=71469","nofollow":true},{"id":23042,"name":"Finite Element","url":"https://www.academia.edu/Documents/in/Finite_Element?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":183165,"name":"Lower Esophageal Sphincter","url":"https://www.academia.edu/Documents/in/Lower_Esophageal_Sphincter?f_ri=71469"},{"id":215075,"name":"Experimental Study","url":"https://www.academia.edu/Documents/in/Experimental_Study?f_ri=71469"},{"id":291387,"name":"Mathematical Model","url":"https://www.academia.edu/Documents/in/Mathematical_Model?f_ri=71469"},{"id":473797,"name":"Microstructures","url":"https://www.academia.edu/Documents/in/Microstructures?f_ri=71469"},{"id":504035,"name":"Three Dimensional","url":"https://www.academia.edu/Documents/in/Three_Dimensional?f_ri=71469"},{"id":1242973,"name":"Gastroesophageal Reflux Disease","url":"https://www.academia.edu/Documents/in/Gastroesophageal_Reflux_Disease?f_ri=71469"},{"id":1372278,"name":"Region of Interest","url":"https://www.academia.edu/Documents/in/Region_of_Interest?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13864643 coauthored" data-work_id="13864643" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13864643/Lower_leg_muscle_atrophy_in_ankle_osteoarthritis">Lower leg muscle atrophy in ankle osteoarthritis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of this study was to determine changes in the lower leg muscles associated with ankle osteoarthritis. Fifteen unilateral ankle osteoarthritis patients and fifteen age-gender-matched normal subjects were assessed with clinical... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13864643" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of this study was to determine changes in the lower leg muscles associated with ankle osteoarthritis. Fifteen unilateral ankle osteoarthritis patients and fifteen age-gender-matched normal subjects were assessed with clinical [osteoarthritis latency time, pain, alignment, AOFAS ankle score, ankle range of motion (ROM), calf circumference], radiological (ankle osteoarthritis grading), and muscular-physiological parameters [isometric maximal voluntary ankle torque, surface electromyography of the anterior tibial (AT), medial gastrocnemius (MG), soleus (SO), and peroneus longus (PL) muscle]. The osteoarthritis patients had increased pain (6.8 points) and reduced AOFAS score (33.7 points) compared to the control group. Compared to the contralateral healthy leg, the arthritic leg showed reduced mean dorsi-/plantar flexion ROM (16.08), reduced mean calf circumference (2.1 cm), smaller mean dorsiflexion (16.4 Nm) and plantar flexion (15.8 Nm) torques, lower mean electromyography frequency for all muscles (AT À22.6 Hz; MG À27.3 Hz; SO À25.9 Hz; PL À28.5 Hz), and lower mean electromyography intensity in the AT [À28.0 Â 10 3 (mv) 2 ], MG [À13.3 Â 10 3 (mv) 2 ], and PL [À12.8 Â 10 3 (mv) 2 ]. SO mean electromyography intensity was not significantly changed [þ2.0 Â 10 3 (mv) 2 ]. Unilateral ankle osteoarthritis is associated with atrophic changes of the lower leg muscles. This study supports previous observations on muscle dysfunction in knee osteoarthritis. ß</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13864643" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c387c4c1e95adf3165c197ba19ee4225" rel="nofollow" data-download="{"attachment_id":44864935,"asset_id":13864643,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44864935/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32952236" href="https://independent.academia.edu/BennoNigg">Benno Nigg</a><script data-card-contents-for-user="32952236" type="text/json">{"id":32952236,"first_name":"Benno","last_name":"Nigg","domain_name":"independent","page_name":"BennoNigg","display_name":"Benno Nigg","profile_url":"https://independent.academia.edu/BennoNigg?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13864643">+1</span><div class="hidden js-additional-users-13864643"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://ucalgary.academia.edu/VinzenzVonTscharner">Vinzenz Von Tscharner</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-13864643'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-13864643').html(); 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Fifteen unilateral ankle osteoarthritis patients and fifteen age-gender-matched normal subjects were assessed with clinical [osteoarthritis latency time, pain, alignment, AOFAS ankle score, ankle range of motion (ROM), calf circumference], radiological (ankle osteoarthritis grading), and muscular-physiological parameters [isometric maximal voluntary ankle torque, surface electromyography of the anterior tibial (AT), medial gastrocnemius (MG), soleus (SO), and peroneus longus (PL) muscle]. The osteoarthritis patients had increased pain (6.8 points) and reduced AOFAS score (33.7 points) compared to the control group. Compared to the contralateral healthy leg, the arthritic leg showed reduced mean dorsi-/plantar flexion ROM (16.08), reduced mean calf circumference (2.1 cm), smaller mean dorsiflexion (16.4 Nm) and plantar flexion (15.8 Nm) torques, lower mean electromyography frequency for all muscles (AT À22.6 Hz; MG À27.3 Hz; SO À25.9 Hz; PL À28.5 Hz), and lower mean electromyography intensity in the AT [À28.0 Â 10 3 (mv) 2 ], MG [À13.3 Â 10 3 (mv) 2 ], and PL [À12.8 Â 10 3 (mv) 2 ]. SO mean electromyography intensity was not significantly changed [þ2.0 Â 10 3 (mv) 2 ]. Unilateral ankle osteoarthritis is associated with atrophic changes of the lower leg muscles. This study supports previous observations on muscle dysfunction in knee osteoarthritis. ß","downloadable_attachments":[{"id":44864935,"asset_id":13864643,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32952236,"first_name":"Benno","last_name":"Nigg","domain_name":"independent","page_name":"BennoNigg","display_name":"Benno Nigg","profile_url":"https://independent.academia.edu/BennoNigg?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":33041437,"first_name":"Vinzenz Von","last_name":"Tscharner","domain_name":"ucalgary","page_name":"VinzenzVonTscharner","display_name":"Vinzenz Von Tscharner","profile_url":"https://ucalgary.academia.edu/VinzenzVonTscharner?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1131,"name":"Biomedical 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class="summarized">Cardiac muscle M-band structures in several mammals (guinea pig, rabbit, rat and cow) and also from three teleosts (plaice, cap and roach), have been studied using electron microscopy and image processing. Axial structure seen in... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_21766465" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Cardiac muscle M-band structures in several mammals (guinea pig, rabbit, rat and cow) and also from three teleosts (plaice, cap and roach), have been studied using electron microscopy and image processing. Axial structure seen in negatively stained isolated myofibrils or negatively stained cryo-sections shows the presence of five strong M-bridge lines (M6, M4, M1, M4' and M6') except in the case of the teleost M-bands in which the central M-line (MI) is absent, giving a four-line M-band. The M4 (M4') lines are consistently strong in all muscles, supporting the suggestion that bridges at this position are important for the structural integrity of the A-band myosin filament lattice. Across the vertebrate kingdom, cardiac M-band ultrastructure appears to correlate roughly with heartbeat frequency, just as in skeletal muscles it correlates with contraction speed, reinforcing the suggestion that some M-band components may have a significant physiological role. Apart from rat heart, which is relatively fast and has a conventional five-line M-band with M1 and M4 approximately equal, the rabbit, guinea pig and beef heart M-bands form a new 1 + 4 class; M1 is relatively very much stronger than M4.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21766465" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="622c8d6baa73480066aa13d1878d76fa" rel="nofollow" data-download="{"attachment_id":42536379,"asset_id":21766465,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42536379/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34145123" href="https://imperial.academia.edu/JohnSquire">John Squire</a><script data-card-contents-for-user="34145123" type="text/json">{"id":34145123,"first_name":"John","last_name":"Squire","domain_name":"imperial","page_name":"JohnSquire","display_name":"John Squire","profile_url":"https://imperial.academia.edu/JohnSquire?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_21766465 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="21766465"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 21766465, container: ".js-paper-rank-work_21766465", }); 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Axial structure seen in negatively stained isolated myofibrils or negatively stained cryo-sections shows the presence of five strong M-bridge lines (M6, M4, M1, M4' and M6') except in the case of the teleost M-bands in which the central M-line (MI) is absent, giving a four-line M-band. The M4 (M4') lines are consistently strong in all muscles, supporting the suggestion that bridges at this position are important for the structural integrity of the A-band myosin filament lattice. Across the vertebrate kingdom, cardiac M-band ultrastructure appears to correlate roughly with heartbeat frequency, just as in skeletal muscles it correlates with contraction speed, reinforcing the suggestion that some M-band components may have a significant physiological role. Apart from rat heart, which is relatively fast and has a conventional five-line M-band with M1 and M4 approximately equal, the rabbit, guinea pig and beef heart M-bands form a new 1 + 4 class; M1 is relatively very much stronger than M4.","downloadable_attachments":[{"id":42536379,"asset_id":21766465,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34145123,"first_name":"John","last_name":"Squire","domain_name":"imperial","page_name":"JohnSquire","display_name":"John Squire","profile_url":"https://imperial.academia.edu/JohnSquire?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":167,"name":"Physiology","url":"https://www.academia.edu/Documents/in/Physiology?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":103254,"name":"Vertebrates","url":"https://www.academia.edu/Documents/in/Vertebrates?f_ri=71469","nofollow":true},{"id":117270,"name":"Fishes","url":"https://www.academia.edu/Documents/in/Fishes?f_ri=71469","nofollow":true},{"id":131298,"name":"Heart rate","url":"https://www.academia.edu/Documents/in/Heart_rate?f_ri=71469"},{"id":202404,"name":"Actin Cytoskeleton","url":"https://www.academia.edu/Documents/in/Actin_Cytoskeleton?f_ri=71469"},{"id":260829,"name":"Cattle","url":"https://www.academia.edu/Documents/in/Cattle?f_ri=71469"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=71469"},{"id":392828,"name":"Myocardium","url":"https://www.academia.edu/Documents/in/Myocardium?f_ri=71469"},{"id":784076,"name":"Species Specificity","url":"https://www.academia.edu/Documents/in/Species_Specificity?f_ri=71469"},{"id":788677,"name":"Rabbits","url":"https://www.academia.edu/Documents/in/Rabbits?f_ri=71469"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20520543 coauthored" data-work_id="20520543" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20520543/Select_Screening_in_a_Specific_High_Risk_Population_of_Patients_Suggests_a_Stage_Migration_Toward_Detection_of_Non_Muscle_Invasive_Bladder_Cancer">Select Screening in a Specific High-Risk Population of Patients Suggests a Stage Migration Toward Detection of Non–Muscle-Invasive Bladder Cancer</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">a v a i l a b l e a t w w w . s c i e n c e d i r e c t . c o m j o u r n a l h o m e p a g e : w w w . e u r o p e a n u r o l o g y . c o m Abstract Background: More than 25% of bladder cancer (BC) cases are still muscle-invasive at... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20520543" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">a v a i l a b l e a t w w w . s c i e n c e d i r e c t . c o m j o u r n a l h o m e p a g e : w w w . e u r o p e a n u r o l o g y . c o m Abstract Background: More than 25% of bladder cancer (BC) cases are still muscle-invasive at first diagnosis. Screening is unproven to enable the detection of more non-muscle-invasive tumors. BC association with aristolochic acid nephropathy (AAN) was reported after intake of slimming pills containing Chinese herbs. Objective: We evaluated whether a BC screening protocol in a high-risk and unique patient population had an impact on the stage of tumor presentation. Design, setting, and participants: Forty-eight AAN-affected patients were enrolled in a screening program, establishing BC incidence during prospective screening cystoscopies and biopsies biannually for up to 10 yr. Two patients were lost to follow-up, and three refused screening after consenting. Measurements: Patients were evaluated for presence of BC and tumor stage at diagnosis. Results and limitations: BC was diagnosed in 25 patients (52%). Among 43 patients who underwent screening cystoscopies (median follow-up: 94 mo), 22 were first diagnosed with non-muscle-invasive BC but none with muscle-invasive tumors and none died of BC. Three women who declined follow-up were diagnosed and died with advanced metastatic disease. The limitations of our findings include the small sample size of this case series, the absence of a real control group, and the particular risk factor in these patients that differs from the usual risk factors, such as smoking or industrial chemicals. Conclusions: BC screening in high-risk groups may allow identification of tumors before muscle invasion. The optimal screening schedule and the relevance of the present findings in smoking-related BC remain to be defined.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20520543" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="406ea0ad03ed2868478fc8bea015d9dc" rel="nofollow" data-download="{"attachment_id":41950163,"asset_id":20520543,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41950163/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41811527" href="https://independent.academia.edu/thierryroumeguere">thierry roumeguere</a><script data-card-contents-for-user="41811527" type="text/json">{"id":41811527,"first_name":"thierry","last_name":"roumeguere","domain_name":"independent","page_name":"thierryroumeguere","display_name":"thierry roumeguere","profile_url":"https://independent.academia.edu/thierryroumeguere?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-20520543">+1</span><div class="hidden js-additional-users-20520543"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/JoelleNortier">Joëlle Nortier</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-20520543'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-20520543').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_20520543 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20520543"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20520543, container: ".js-paper-rank-work_20520543", }); });</script></li><li class="js-percentile-work_20520543 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20520543; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_20520543"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_20520543 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="20520543"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20520543; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20520543]").text(description); $(".js-view-count-work_20520543").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20520543").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20520543"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">23</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="622" rel="nofollow" href="https://www.academia.edu/Documents/in/Nephrology">Nephrology</a>, <script data-card-contents-for-ri="622" type="text/json">{"id":622,"name":"Nephrology","url":"https://www.academia.edu/Documents/in/Nephrology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="653" rel="nofollow" href="https://www.academia.edu/Documents/in/Urology">Urology</a>, <script data-card-contents-for-ri="653" type="text/json">{"id":653,"name":"Urology","url":"https://www.academia.edu/Documents/in/Urology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6021" rel="nofollow" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8863" rel="nofollow" href="https://www.academia.edu/Documents/in/Cell_Migration">Cell Migration</a><script data-card-contents-for-ri="8863" type="text/json">{"id":8863,"name":"Cell Migration","url":"https://www.academia.edu/Documents/in/Cell_Migration?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20520543]'), work: {"id":20520543,"title":"Select Screening in a Specific High-Risk Population of Patients Suggests a Stage Migration Toward Detection of Non–Muscle-Invasive Bladder Cancer","created_at":"2016-01-22T04:10:59.487-08:00","url":"https://www.academia.edu/20520543/Select_Screening_in_a_Specific_High_Risk_Population_of_Patients_Suggests_a_Stage_Migration_Toward_Detection_of_Non_Muscle_Invasive_Bladder_Cancer?f_ri=71469","dom_id":"work_20520543","summary":"a v a i l a b l e a t w w w . s c i e n c e d i r e c t . c o m j o u r n a l h o m e p a g e : w w w . e u r o p e a n u r o l o g y . c o m Abstract Background: More than 25% of bladder cancer (BC) cases are still muscle-invasive at first diagnosis. Screening is unproven to enable the detection of more non-muscle-invasive tumors. BC association with aristolochic acid nephropathy (AAN) was reported after intake of slimming pills containing Chinese herbs. Objective: We evaluated whether a BC screening protocol in a high-risk and unique patient population had an impact on the stage of tumor presentation. Design, setting, and participants: Forty-eight AAN-affected patients were enrolled in a screening program, establishing BC incidence during prospective screening cystoscopies and biopsies biannually for up to 10 yr. Two patients were lost to follow-up, and three refused screening after consenting. Measurements: Patients were evaluated for presence of BC and tumor stage at diagnosis. Results and limitations: BC was diagnosed in 25 patients (52%). Among 43 patients who underwent screening cystoscopies (median follow-up: 94 mo), 22 were first diagnosed with non-muscle-invasive BC but none with muscle-invasive tumors and none died of BC. Three women who declined follow-up were diagnosed and died with advanced metastatic disease. The limitations of our findings include the small sample size of this case series, the absence of a real control group, and the particular risk factor in these patients that differs from the usual risk factors, such as smoking or industrial chemicals. Conclusions: BC screening in high-risk groups may allow identification of tumors before muscle invasion. The optimal screening schedule and the relevance of the present findings in smoking-related BC remain to be defined.","downloadable_attachments":[{"id":41950163,"asset_id":20520543,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41811527,"first_name":"thierry","last_name":"roumeguere","domain_name":"independent","page_name":"thierryroumeguere","display_name":"thierry roumeguere","profile_url":"https://independent.academia.edu/thierryroumeguere?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":42004571,"first_name":"Joëlle","last_name":"Nortier","domain_name":"independent","page_name":"JoelleNortier","display_name":"Joëlle Nortier","profile_url":"https://independent.academia.edu/JoelleNortier?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":622,"name":"Nephrology","url":"https://www.academia.edu/Documents/in/Nephrology?f_ri=71469","nofollow":true},{"id":653,"name":"Urology","url":"https://www.academia.edu/Documents/in/Urology?f_ri=71469","nofollow":true},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=71469","nofollow":true},{"id":8863,"name":"Cell Migration","url":"https://www.academia.edu/Documents/in/Cell_Migration?f_ri=71469","nofollow":true},{"id":8999,"name":"Kidney diseases","url":"https://www.academia.edu/Documents/in/Kidney_diseases?f_ri=71469"},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=71469"},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=71469"},{"id":43363,"name":"Screening","url":"https://www.academia.edu/Documents/in/Screening?f_ri=71469"},{"id":58274,"name":"Bladder Cancer","url":"https://www.academia.edu/Documents/in/Bladder_Cancer?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":174804,"name":"Fibrosis","url":"https://www.academia.edu/Documents/in/Fibrosis?f_ri=71469"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=71469"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469"},{"id":357850,"name":"Atrophy","url":"https://www.academia.edu/Documents/in/Atrophy?f_ri=71469"},{"id":371494,"name":"Neoplasm Invasiveness","url":"https://www.academia.edu/Documents/in/Neoplasm_Invasiveness?f_ri=71469"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=71469"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=71469"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=71469"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=71469"},{"id":774352,"name":"Stage","url":"https://www.academia.edu/Documents/in/Stage?f_ri=71469"},{"id":843139,"name":"Cystoscopy","url":"https://www.academia.edu/Documents/in/Cystoscopy?f_ri=71469"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=71469"},{"id":1345117,"name":"Aristolochic Acid","url":"https://www.academia.edu/Documents/in/Aristolochic_Acid?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_42325456 coauthored" data-work_id="42325456" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/42325456/PECTORAL_MUSCLE_EXTRACTION_USING_GRAY_THRESHOLD_METHOD_IN_A_MAMMOGRAM">PECTORAL MUSCLE EXTRACTION USING GRAY THRESHOLD METHOD IN A MAMMOGRAM</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Noise reduction and pectoral muscles are the two essential pre diagnosis. This work introduced eliminates Gaussian and pulsing noise with great e gray thresholding to recognize pectoral muscles for segmentation and removal of pectoral... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_42325456" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Noise reduction and pectoral muscles are the two essential pre diagnosis. This work introduced eliminates Gaussian and pulsing noise with great e gray thresholding to recognize pectoral muscles for segmentation and removal of pectoral muscles, applies morphological operations to identify the edge of the entire breast and connected part remove the connected pixels outside the breast region with the help of MATLAB tool.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/42325456" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="827e07d58482bb5560321ffafef3bb72" rel="nofollow" data-download="{"attachment_id":62482136,"asset_id":42325456,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/62482136/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="13733577" rel="nofollow" href="https://iiitb.academia.edu/IJIRAEInternationalJournalofInnovativeResearchinAdvancedEngineering">IJIRAE - International Journal of Innovative Research in Advanced Engineering</a><script data-card-contents-for-user="13733577" type="text/json">{"id":13733577,"first_name":"IJIRAE","last_name":"International Journal of Innovative Research in Advanced Engineering","domain_name":"iiitb","page_name":"IJIRAEInternationalJournalofInnovativeResearchinAdvancedEngineering","display_name":"IJIRAE - International Journal of Innovative Research in Advanced Engineering","profile_url":"https://iiitb.academia.edu/IJIRAEInternationalJournalofInnovativeResearchinAdvancedEngineering?f_ri=71469","photo":"https://0.academia-photos.com/13733577/3819053/35118444/s65_ijirae.international_journal_of_innovative_research_in_advanced_engineering.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-42325456">+2</span><div class="hidden js-additional-users-42325456"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/JincyDenny">Jincy Denny</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/SobhaT2">Sobha T</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-42325456'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-42325456').html(); 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This work introduced eliminates Gaussian and pulsing noise with great e gray thresholding to recognize pectoral muscles for segmentation and removal of pectoral muscles, applies morphological operations to identify the edge of the entire breast and connected part remove the connected pixels outside the breast region with the help of MATLAB tool.","downloadable_attachments":[{"id":62482136,"asset_id":42325456,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":13733577,"first_name":"IJIRAE","last_name":"International Journal of Innovative Research in Advanced Engineering","domain_name":"iiitb","page_name":"IJIRAEInternationalJournalofInnovativeResearchinAdvancedEngineering","display_name":"IJIRAE - International Journal of Innovative Research in Advanced Engineering","profile_url":"https://iiitb.academia.edu/IJIRAEInternationalJournalofInnovativeResearchinAdvancedEngineering?f_ri=71469","photo":"https://0.academia-photos.com/13733577/3819053/35118444/s65_ijirae.international_journal_of_innovative_research_in_advanced_engineering.jpg"},{"id":114131066,"first_name":"Jincy","last_name":"Denny","domain_name":"independent","page_name":"JincyDenny","display_name":"Jincy Denny","profile_url":"https://independent.academia.edu/JincyDenny?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":112338340,"first_name":"Sobha","last_name":"T","domain_name":"independent","page_name":"SobhaT2","display_name":"Sobha T","profile_url":"https://independent.academia.edu/SobhaT2?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":25395,"name":"Matlab","url":"https://www.academia.edu/Documents/in/Matlab?f_ri=71469","nofollow":true},{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=71469","nofollow":true},{"id":47331,"name":"Physiological and biomechanical mechanisms of skeletal muscle function","url":"https://www.academia.edu/Documents/in/Physiological_and_biomechanical_mechanisms_of_skeletal_muscle_function?f_ri=71469","nofollow":true},{"id":61636,"name":"Matlab Programming","url":"https://www.academia.edu/Documents/in/Matlab_Programming?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":121039,"name":"MATLAB code","url":"https://www.academia.edu/Documents/in/MATLAB_code?f_ri=71469"},{"id":155948,"name":"Thresholding","url":"https://www.academia.edu/Documents/in/Thresholding?f_ri=71469"},{"id":156783,"name":"Face recognition using MATLAB","url":"https://www.academia.edu/Documents/in/Face_recognition_using_MATLAB?f_ri=71469"},{"id":186105,"name":"Matlab/Simulink","url":"https://www.academia.edu/Documents/in/Matlab_Simulink?f_ri=71469"},{"id":228127,"name":"Ofdm Used with Matlab","url":"https://www.academia.edu/Documents/in/Ofdm_Used_with_Matlab?f_ri=71469"},{"id":300330,"name":"Matlab \u0026 Simulink programming","url":"https://www.academia.edu/Documents/in/Matlab_and_Simulink_programming?f_ri=71469"},{"id":306398,"name":"Matlab Gui","url":"https://www.academia.edu/Documents/in/Matlab_Gui?f_ri=71469"},{"id":325302,"name":"Visitor Counter Using MATLAB","url":"https://www.academia.edu/Documents/in/Visitor_Counter_Using_MATLAB?f_ri=71469"},{"id":409710,"name":"Face Recognition Matlab Code","url":"https://www.academia.edu/Documents/in/Face_Recognition_Matlab_Code?f_ri=71469"},{"id":513289,"name":"The Portrait of Dorian Gray","url":"https://www.academia.edu/Documents/in/The_Portrait_of_Dorian_Gray?f_ri=71469"},{"id":850838,"name":"Noise Removal","url":"https://www.academia.edu/Documents/in/Noise_Removal?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_9443157" data-work_id="9443157" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/9443157/Physicochemical_and_functional_changes_in_jumbo_squid_Dosidicus_gigas_mantle_muscle_during_ice_storage">Physicochemical and functional changes in jumbo squid ( Dosidicus gigas) mantle muscle during ice storage</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Physicochemical and functional changes of jumbo squid (Dosidicus gigas) mantle muscle stored in ice for 15 days were evaluated. Proximate analysis, pH, protein solubility (PS) and SDS-PAGE profile changes were monitored for muscle... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_9443157" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Physicochemical and functional changes of jumbo squid (Dosidicus gigas) mantle muscle stored in ice for 15 days were evaluated. Proximate analysis, pH, protein solubility (PS) and SDS-PAGE profile changes were monitored for muscle proteins, while texture profile analysis (TPA) (gel strength, elasticity and cohesiveness), water holding capacity (WHC) and colour changes were monitored for gels produced from this muscle. Fresh muscle chemical composition varied according to fishing season and/or physiological status presented by specimens. pH and PS were stable (p P 0.05) throughout the study with a slight tendency to decrease towards the end of study. SDS-PAGE revealed no drastic changes in proteins influencing gelation (i.e., myosin). TPA and WHC of gels decreased towards the end of experiment; however, due to sampling variability, no significant differences (p P 0.05) were found over storage time. Changes in gel colour were observed with hue angle decreasing towards yellow hues. Improved post-capture management of mantle muscle preserved its integrity and functionality for up to two weeks.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/9443157" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f8b8e87eaac68354864c1c50f9b27738" rel="nofollow" data-download="{"attachment_id":47778367,"asset_id":9443157,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47778367/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="22005266" href="https://utcn.academia.edu/JuanLuisGarciaLugo">Juan Luis Garcia Lugo</a><script data-card-contents-for-user="22005266" type="text/json">{"id":22005266,"first_name":"Juan Luis","last_name":"Garcia Lugo","domain_name":"utcn","page_name":"JuanLuisGarciaLugo","display_name":"Juan Luis Garcia Lugo","profile_url":"https://utcn.academia.edu/JuanLuisGarciaLugo?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_9443157 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="9443157"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 9443157, container: ".js-paper-rank-work_9443157", }); 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Proximate analysis, pH, protein solubility (PS) and SDS-PAGE profile changes were monitored for muscle proteins, while texture profile analysis (TPA) (gel strength, elasticity and cohesiveness), water holding capacity (WHC) and colour changes were monitored for gels produced from this muscle. Fresh muscle chemical composition varied according to fishing season and/or physiological status presented by specimens. pH and PS were stable (p P 0.05) throughout the study with a slight tendency to decrease towards the end of study. SDS-PAGE revealed no drastic changes in proteins influencing gelation (i.e., myosin). TPA and WHC of gels decreased towards the end of experiment; however, due to sampling variability, no significant differences (p P 0.05) were found over storage time. Changes in gel colour were observed with hue angle decreasing towards yellow hues. Improved post-capture management of mantle muscle preserved its integrity and functionality for up to two weeks.","downloadable_attachments":[{"id":47778367,"asset_id":9443157,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":22005266,"first_name":"Juan Luis","last_name":"Garcia Lugo","domain_name":"utcn","page_name":"JuanLuisGarciaLugo","display_name":"Juan Luis Garcia Lugo","profile_url":"https://utcn.academia.edu/JuanLuisGarciaLugo?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7598,"name":"Rheology","url":"https://www.academia.edu/Documents/in/Rheology?f_ri=71469","nofollow":true},{"id":16137,"name":"Food Chemistry","url":"https://www.academia.edu/Documents/in/Food_Chemistry?f_ri=71469","nofollow":true},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=71469","nofollow":true},{"id":39718,"name":"Food Preservation","url":"https://www.academia.edu/Documents/in/Food_Preservation?f_ri=71469","nofollow":true},{"id":57433,"name":"Seasonality","url":"https://www.academia.edu/Documents/in/Seasonality?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":371425,"name":"Electrophoresis","url":"https://www.academia.edu/Documents/in/Electrophoresis?f_ri=71469"},{"id":403452,"name":"Warehousing","url":"https://www.academia.edu/Documents/in/Warehousing?f_ri=71469"},{"id":592246,"name":"Cold","url":"https://www.academia.edu/Documents/in/Cold?f_ri=71469"},{"id":772972,"name":"Chemical Composition","url":"https://www.academia.edu/Documents/in/Chemical_Composition?f_ri=71469"},{"id":858489,"name":"Cold Storage","url":"https://www.academia.edu/Documents/in/Cold_Storage?f_ri=71469"},{"id":1123384,"name":"Texture profile analysis","url":"https://www.academia.edu/Documents/in/Texture_profile_analysis?f_ri=71469"},{"id":1216935,"name":"Electroforesis","url":"https://www.academia.edu/Documents/in/Electroforesis?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12911720" data-work_id="12911720" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12911720/Muscle_strengthening_and_physical_conditioning_to_reduce_impairment_and_disability_in_chronic_stroke_survivors">Muscle strengthening and physical conditioning to reduce impairment and disability in chronic stroke survivors</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Teixeira-Salmela LF, Olney SJ, Nadeau S, Brouwer B. Muscle strengthening and physical conditioning to reduce impairment and disability in chronic stroke survivors. Arch Phys Med Rehabil 1999;80:1211-8.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12911720" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e8f80bd35432e918f2d154b9ee1d8ae5" rel="nofollow" data-download="{"attachment_id":45851269,"asset_id":12911720,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45851269/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32076526" href="https://ufmg.academia.edu/LuciTeixeiraSalmela">Luci Teixeira-Salmela</a><script data-card-contents-for-user="32076526" type="text/json">{"id":32076526,"first_name":"Luci","last_name":"Teixeira-Salmela","domain_name":"ufmg","page_name":"LuciTeixeiraSalmela","display_name":"Luci Teixeira-Salmela","profile_url":"https://ufmg.academia.edu/LuciTeixeiraSalmela?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12911720 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12911720"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12911720, container: ".js-paper-rank-work_12911720", }); 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$(".js-view-count[data-work-id=12911720]").text(description); $(".js-view-count-work_12911720").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_12911720").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="12911720"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">24</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="202" rel="nofollow" href="https://www.academia.edu/Documents/in/Program_Evaluation">Program Evaluation</a>, <script data-card-contents-for-ri="202" type="text/json">{"id":202,"name":"Program Evaluation","url":"https://www.academia.edu/Documents/in/Program_Evaluation?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8910" rel="nofollow" href="https://www.academia.edu/Documents/in/Evaluation">Evaluation</a>, <script data-card-contents-for-ri="8910" type="text/json">{"id":8910,"name":"Evaluation","url":"https://www.academia.edu/Documents/in/Evaluation?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8942" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment">Treatment</a>, <script data-card-contents-for-ri="8942" type="text/json">{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a><script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=12911720]'), work: {"id":12911720,"title":"Muscle strengthening and physical conditioning to reduce impairment and disability in chronic stroke survivors","created_at":"2015-06-10T15:20:32.295-07:00","url":"https://www.academia.edu/12911720/Muscle_strengthening_and_physical_conditioning_to_reduce_impairment_and_disability_in_chronic_stroke_survivors?f_ri=71469","dom_id":"work_12911720","summary":"Teixeira-Salmela LF, Olney SJ, Nadeau S, Brouwer B. Muscle strengthening and physical conditioning to reduce impairment and disability in chronic stroke survivors. Arch Phys Med Rehabil 1999;80:1211-8.","downloadable_attachments":[{"id":45851269,"asset_id":12911720,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32076526,"first_name":"Luci","last_name":"Teixeira-Salmela","domain_name":"ufmg","page_name":"LuciTeixeiraSalmela","display_name":"Luci Teixeira-Salmela","profile_url":"https://ufmg.academia.edu/LuciTeixeiraSalmela?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":202,"name":"Program Evaluation","url":"https://www.academia.edu/Documents/in/Program_Evaluation?f_ri=71469","nofollow":true},{"id":8910,"name":"Evaluation","url":"https://www.academia.edu/Documents/in/Evaluation?f_ri=71469","nofollow":true},{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=71469","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=71469","nofollow":true},{"id":25443,"name":"Exercise 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data-has-card-for-ri="2184" rel="nofollow" href="https://www.academia.edu/Documents/in/Electron_Microscopy">Electron Microscopy</a>, <script data-card-contents-for-ri="2184" type="text/json">{"id":2184,"name":"Electron Microscopy","url":"https://www.academia.edu/Documents/in/Electron_Microscopy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a><script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=18986053]'), work: {"id":18986053,"title":"Morphological changes in muscle tissue of patients with infantile Pompe's disease receiving enzyme replacement 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In all, 629 older persons without dementia underwent testing including 11 lower extremity performance measures and modified United Parkinson's... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_3402251" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We tested the hypothesis that vibratory thresholds in the elderly are related to mobility. In all, 629 older persons without dementia underwent testing including 11 lower extremity performance measures and modified United Parkinson's Disease Rating Scale (UPDRS), summarized as composite mobility and global parkinsonian signs. Vibratory thresholds were measured at the ankle and toes bilaterally using the graduated Rydel–Seiffer tuning fork. In linear regression models adjusted for age, sex, and education, vibratory threshold was associated with composite mobility (estimate, 0.047, SE = 0.011, P < 0.001) and global parkinsonian signs score (estimate, −0.252, SE = 0.126, P = 0.047). These findings were primarily due to the association of vibratory threshold with gait and balance components of composite mobility and parkinsonian gait. These results were unchanged when we controlled for body mass index, physical activity, cognition, depression, vascular risk factors, vascular disease burden, joint pain, and falls. Vibratory thresholds are associated with mobility, supporting the link between peripheral sensory nerve function and mobility in the elderly. Muscle Nerve, 2009</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3402251" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8f94a0d9a8381675e91b4cf875b6bd1c" rel="nofollow" data-download="{"attachment_id":50298058,"asset_id":3402251,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50298058/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3960686" href="https://rushmore.academia.edu/AronBuchman">Aron Buchman</a><script data-card-contents-for-user="3960686" type="text/json">{"id":3960686,"first_name":"Aron","last_name":"Buchman","domain_name":"rushmore","page_name":"AronBuchman","display_name":"Aron Buchman","profile_url":"https://rushmore.academia.edu/AronBuchman?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_3402251 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3402251"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3402251, container: ".js-paper-rank-work_3402251", }); 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In all, 629 older persons without dementia underwent testing including 11 lower extremity performance measures and modified United Parkinson's Disease Rating Scale (UPDRS), summarized as composite mobility and global parkinsonian signs. Vibratory thresholds were measured at the ankle and toes bilaterally using the graduated Rydel–Seiffer tuning fork. In linear regression models adjusted for age, sex, and education, vibratory threshold was associated with composite mobility (estimate, 0.047, SE = 0.011, P \u003c 0.001) and global parkinsonian signs score (estimate, −0.252, SE = 0.126, P = 0.047). These findings were primarily due to the association of vibratory threshold with gait and balance components of composite mobility and parkinsonian gait. These results were unchanged when we controlled for body mass index, physical activity, cognition, depression, vascular risk factors, vascular disease burden, joint pain, and falls. Vibratory thresholds are associated with mobility, supporting the link between peripheral sensory nerve function and mobility in the elderly. Muscle Nerve, 2009","downloadable_attachments":[{"id":50298058,"asset_id":3402251,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3960686,"first_name":"Aron","last_name":"Buchman","domain_name":"rushmore","page_name":"AronBuchman","display_name":"Aron Buchman","profile_url":"https://rushmore.academia.edu/AronBuchman?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4212,"name":"Cognition","url":"https://www.academia.edu/Documents/in/Cognition?f_ri=71469","nofollow":true},{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=71469","nofollow":true},{"id":23077,"name":"Vibration","url":"https://www.academia.edu/Documents/in/Vibration?f_ri=71469","nofollow":true},{"id":43367,"name":"Movement disorders","url":"https://www.academia.edu/Documents/in/Movement_disorders?f_ri=71469"},{"id":50690,"name":"Mobility","url":"https://www.academia.edu/Documents/in/Mobility?f_ri=71469"},{"id":54214,"name":"Proprioception","url":"https://www.academia.edu/Documents/in/Proprioception?f_ri=71469"},{"id":56503,"name":"Linear Model","url":"https://www.academia.edu/Documents/in/Linear_Model?f_ri=71469"},{"id":60256,"name":"Gait","url":"https://www.academia.edu/Documents/in/Gait?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":83312,"name":"TOE","url":"https://www.academia.edu/Documents/in/TOE?f_ri=71469"},{"id":123230,"name":"Regression Analysis","url":"https://www.academia.edu/Documents/in/Regression_Analysis?f_ri=71469"},{"id":128559,"name":"Mechanoreceptors","url":"https://www.academia.edu/Documents/in/Mechanoreceptors?f_ri=71469"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=71469"},{"id":670043,"name":"Joints","url":"https://www.academia.edu/Documents/in/Joints?f_ri=71469"},{"id":795003,"name":"Linear Regression","url":"https://www.academia.edu/Documents/in/Linear_Regression?f_ri=71469"},{"id":1318932,"name":"Predictive value of tests","url":"https://www.academia.edu/Documents/in/Predictive_value_of_tests?f_ri=71469"},{"id":1541077,"name":"Parkinson Disease","url":"https://www.academia.edu/Documents/in/Parkinson_Disease?f_ri=71469"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=71469"},{"id":2450536,"name":"Mobility limitation","url":"https://www.academia.edu/Documents/in/Mobility_limitation?f_ri=71469"},{"id":2474752,"name":"Disability Evaluation","url":"https://www.academia.edu/Documents/in/Disability_Evaluation?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11686031" data-work_id="11686031" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11686031/Immunopathogenic_pathways_in_canine_inflammatory_myopathies_resemble_human_myositis">Immunopathogenic pathways in canine inflammatory myopathies resemble human myositis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Progress in the treatment of inflammatory myopathies is impeded by the lack of suitable animal models. Inflammatory myopathies occur spontaneously in the dog, are a heterogeneous group of disorders, and are more common than in humans.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_11686031" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Progress in the treatment of inflammatory myopathies is impeded by the lack of suitable animal models. Inflammatory myopathies occur spontaneously in the dog, are a heterogeneous group of disorders, and are more common than in humans. Clinical signs of weakness and muscle atrophy are reliably present, and there are histological and immunohistological similarities to forms of human myositis. In this study, microarray technology followed by quantitative real-time PCR and immunohistochemistry on muscle biopsy sections was used to investigate gene expression in cases of canine inflammatory myopathies. Several genes involved with innate and adaptive immunity were highly upregulated including those that participate in macrophage and dendritic cell activation and migration, and antigen processing and presentation. Other genes including those that participate in B cell growth, development, migration and activation, immunoglobulin genes, genes in pro-inflammatory and anti-inflammatory pathways, and genes involved with tissue remodeling were upregulated. In previous reports utilizing microarray technology in human myositis, there was activation of similar pathways involved in the immune response. This study strengthens the argument that forms of canine myositis may be important animal models of human myositis and suggests useful biomarkers for therapeutic response using the dog in pre-clinical trials. #</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11686031" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="abfdcc8fb7a65f88df52deba9d00ab84" rel="nofollow" data-download="{"attachment_id":46575125,"asset_id":11686031,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46575125/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="28602712" href="https://independent.academia.edu/SvetlanaGhimbovschi">Svetlana Ghimbovschi</a><script data-card-contents-for-user="28602712" type="text/json">{"id":28602712,"first_name":"Svetlana","last_name":"Ghimbovschi","domain_name":"independent","page_name":"SvetlanaGhimbovschi","display_name":"Svetlana Ghimbovschi","profile_url":"https://independent.academia.edu/SvetlanaGhimbovschi?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_11686031 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11686031"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11686031, container: ".js-paper-rank-work_11686031", }); 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Inflammatory myopathies occur spontaneously in the dog, are a heterogeneous group of disorders, and are more common than in humans. Clinical signs of weakness and muscle atrophy are reliably present, and there are histological and immunohistological similarities to forms of human myositis. In this study, microarray technology followed by quantitative real-time PCR and immunohistochemistry on muscle biopsy sections was used to investigate gene expression in cases of canine inflammatory myopathies. Several genes involved with innate and adaptive immunity were highly upregulated including those that participate in macrophage and dendritic cell activation and migration, and antigen processing and presentation. Other genes including those that participate in B cell growth, development, migration and activation, immunoglobulin genes, genes in pro-inflammatory and anti-inflammatory pathways, and genes involved with tissue remodeling were upregulated. In previous reports utilizing microarray technology in human myositis, there was activation of similar pathways involved in the immune response. This study strengthens the argument that forms of canine myositis may be important animal models of human myositis and suggests useful biomarkers for therapeutic response using the dog in pre-clinical trials. #","downloadable_attachments":[{"id":46575125,"asset_id":11686031,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":28602712,"first_name":"Svetlana","last_name":"Ghimbovschi","domain_name":"independent","page_name":"SvetlanaGhimbovschi","display_name":"Svetlana Ghimbovschi","profile_url":"https://independent.academia.edu/SvetlanaGhimbovschi?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology?f_ri=71469","nofollow":true},{"id":2702,"name":"Immune response","url":"https://www.academia.edu/Documents/in/Immune_response?f_ri=71469","nofollow":true},{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":4531,"name":"Clinical Trial","url":"https://www.academia.edu/Documents/in/Clinical_Trial?f_ri=71469","nofollow":true},{"id":9111,"name":"Cytokines","url":"https://www.academia.edu/Documents/in/Cytokines?f_ri=71469"},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=71469"},{"id":27784,"name":"Gene expression","url":"https://www.academia.edu/Documents/in/Gene_expression?f_ri=71469"},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=71469"},{"id":52438,"name":"Dogs","url":"https://www.academia.edu/Documents/in/Dogs?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":88770,"name":"Adaptive Immunity","url":"https://www.academia.edu/Documents/in/Adaptive_Immunity?f_ri=71469"},{"id":135249,"name":"Antigen Processing","url":"https://www.academia.edu/Documents/in/Antigen_Processing?f_ri=71469"},{"id":151951,"name":"Animal Model","url":"https://www.academia.edu/Documents/in/Animal_Model?f_ri=71469"},{"id":153279,"name":"Dendritic cell","url":"https://www.academia.edu/Documents/in/Dendritic_cell?f_ri=71469"},{"id":407851,"name":"Myositis","url":"https://www.academia.edu/Documents/in/Myositis?f_ri=71469"},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=71469"},{"id":678853,"name":"B Lymphocytes","url":"https://www.academia.edu/Documents/in/B_Lymphocytes?f_ri=71469"},{"id":782120,"name":"Veterinary Immunology","url":"https://www.academia.edu/Documents/in/Veterinary_Immunology?f_ri=71469"},{"id":988725,"name":"Clinical Signs","url":"https://www.academia.edu/Documents/in/Clinical_Signs?f_ri=71469"},{"id":1312086,"name":"Immunoglobulins","url":"https://www.academia.edu/Documents/in/Immunoglobulins?f_ri=71469"},{"id":1426712,"name":"Immunoglobulin","url":"https://www.academia.edu/Documents/in/Immunoglobulin?f_ri=71469"},{"id":1810445,"name":"Gene expression profiling","url":"https://www.academia.edu/Documents/in/Gene_expression_profiling?f_ri=71469"},{"id":1954130,"name":"Cell Growth","url":"https://www.academia.edu/Documents/in/Cell_Growth?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17728220 coauthored" data-work_id="17728220" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17728220/ULTRA_RAPID_CHILLING_CHILLING_RATE_EFFECTS_ON_THE_APPEARANCE_OF_LAMB_CARCASSES_AND_TENDERNESS_OF_LAMB_CHOPS">ULTRA-RAPID CHILLING: CHILLING RATE EFFECTS ON THE APPEARANCE OF LAMB CARCASSES AND TENDERNESS OF LAMB CHOPS</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">... Bendall 1972). In recent years, evidence has been growing that very rapid chilling of lamb carcasses may be used without losses in tenderness (Bowling et al. 1987;Sheridan 1990; Jaime et at. 1992; McGeehin et al. 1999). A ...</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17728220" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="20153c68ab2ee7e36cf6c9a6d0480cd8" rel="nofollow" data-download="{"attachment_id":42235174,"asset_id":17728220,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42235174/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37632694" href="https://independent.academia.edu/GrainneRedmond">Grainne Redmond</a><script data-card-contents-for-user="37632694" type="text/json">{"id":37632694,"first_name":"Grainne","last_name":"Redmond","domain_name":"independent","page_name":"GrainneRedmond","display_name":"Grainne Redmond","profile_url":"https://independent.academia.edu/GrainneRedmond?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-17728220">+1</span><div class="hidden js-additional-users-17728220"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://worldpharmacare.academia.edu/BMcGeehin">B. McGeehin</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-17728220'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-17728220').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_17728220 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="17728220"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 17728220, container: ".js-paper-rank-work_17728220", }); });</script></li><li class="js-percentile-work_17728220 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17728220; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_17728220"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_17728220 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="17728220"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17728220; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17728220]").text(description); $(".js-view-count-work_17728220").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17728220").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17728220"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">2</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="573653" rel="nofollow" href="https://www.academia.edu/Documents/in/Food_Sciences">Food Sciences</a><script data-card-contents-for-ri="573653" type="text/json">{"id":573653,"name":"Food Sciences","url":"https://www.academia.edu/Documents/in/Food_Sciences?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17728220]'), work: {"id":17728220,"title":"ULTRA-RAPID CHILLING: CHILLING RATE EFFECTS ON THE APPEARANCE OF LAMB CARCASSES AND TENDERNESS OF LAMB CHOPS","created_at":"2015-11-04T04:34:33.560-08:00","url":"https://www.academia.edu/17728220/ULTRA_RAPID_CHILLING_CHILLING_RATE_EFFECTS_ON_THE_APPEARANCE_OF_LAMB_CARCASSES_AND_TENDERNESS_OF_LAMB_CHOPS?f_ri=71469","dom_id":"work_17728220","summary":"... Bendall 1972). In recent years, evidence has been growing that very rapid chilling of lamb carcasses may be used without losses in tenderness (Bowling et al. 1987;Sheridan 1990; Jaime et at. 1992; McGeehin et al. 1999). A ...","downloadable_attachments":[{"id":42235174,"asset_id":17728220,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37632694,"first_name":"Grainne","last_name":"Redmond","domain_name":"independent","page_name":"GrainneRedmond","display_name":"Grainne Redmond","profile_url":"https://independent.academia.edu/GrainneRedmond?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":37720510,"first_name":"B.","last_name":"McGeehin","domain_name":"worldpharmacare","page_name":"BMcGeehin","display_name":"B. McGeehin","profile_url":"https://worldpharmacare.academia.edu/BMcGeehin?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":573653,"name":"Food Sciences","url":"https://www.academia.edu/Documents/in/Food_Sciences?f_ri=71469","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_7252358" data-work_id="7252358" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/7252358/An_improved_method_of_cell_culture_system_from_eye_stalk_hepatopancreas_muscle_ovary_and_hemocytes_of_Penaeus_vannamei">An improved method of cell culture system from eye stalk, hepatopancreas, muscle, ovary, and hemocytes of Penaeus vannamei</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Improved methods of cell culture from eye stalk, hepatopancreas, muscle, ovary, and hemocytes of shrimp (Penaeus vannamei) were established using synthetic media and shrimp muscle extract (SME). For hemocytes and ovarian cell cultures,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_7252358" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Improved methods of cell culture from eye stalk, hepatopancreas, muscle, ovary, and hemocytes of shrimp (Penaeus vannamei) were established using synthetic media and shrimp muscle extract (SME). For hemocytes and ovarian cell cultures, Grace’s insect medium supplemented with 10% (v/v) fetal bovine serum and 10% SME (v/v) showed enhanced attachment and proliferation of the cells. The hemocyte and ovarian cell cultures could be maintained for 48 and 66 days, respectively, and have been sub-cultured four and six times, respectively. Both ovary and hemocyte cell cultures contained primarily epithelial-like cells. Cells derived from ovary tissue grew preferably between 26°C and 28°C with 5% CO2. Although the temperature preference of hemocyte cells was the same as ovarian cells, CO2 supplementation did not show any difference in the growth of hemocyte cells. When the shrimp were injected with lipopolysaccharide (8 μg/g of shrimp) and hemolymph was drawn 24 h post-injection, the in vitro multiplicity of hemocytes dramatically improved. The growth of eye stalk, hepatopancreas, and muscle-derived cells was much less compared to ovarian cells and hemocytes under the conditions described above. The optimal culture conditions for ovarian cells and hemocytes were also different from that for eye stalk, hepatopancreas, and muscle cell culture. The proliferation efficiencies of primary cultures of hepatopancreas, eyestalk, and muscle cells were about 30, 12, and <7 d, respectively. The improved culture conditions described here, particularly for hemocytes and ovary, will be very useful for in vitro studies involving viruses infecting shrimp and in shrimp genomic studies.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/7252358" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a35052996031a455936fde28c6288c13" rel="nofollow" data-download="{"attachment_id":48548723,"asset_id":7252358,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48548723/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="12637212" href="https://independent.academia.edu/DharArun">Arun Dhar</a><script data-card-contents-for-user="12637212" type="text/json">{"id":12637212,"first_name":"Arun","last_name":"Dhar","domain_name":"independent","page_name":"DharArun","display_name":"Arun Dhar","profile_url":"https://independent.academia.edu/DharArun?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_7252358 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="7252358"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 7252358, container: ".js-paper-rank-work_7252358", }); 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$(".js-view-count[data-work-id=7252358]").text(description); $(".js-view-count-work_7252358").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_7252358").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="7252358"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="156" rel="nofollow" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="173" rel="nofollow" href="https://www.academia.edu/Documents/in/Zoology">Zoology</a>, <script data-card-contents-for-ri="173" type="text/json">{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4594" rel="nofollow" href="https://www.academia.edu/Documents/in/Carbon_Dioxide">Carbon Dioxide</a>, <script data-card-contents-for-ri="4594" type="text/json">{"id":4594,"name":"Carbon Dioxide","url":"https://www.academia.edu/Documents/in/Carbon_Dioxide?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37782" rel="nofollow" href="https://www.academia.edu/Documents/in/Cell_Culture">Cell Culture</a><script data-card-contents-for-ri="37782" type="text/json">{"id":37782,"name":"Cell Culture","url":"https://www.academia.edu/Documents/in/Cell_Culture?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=7252358]'), work: {"id":7252358,"title":"An improved method of cell culture system from eye stalk, hepatopancreas, muscle, ovary, and hemocytes of Penaeus vannamei","created_at":"2014-06-04T00:11:31.745-07:00","url":"https://www.academia.edu/7252358/An_improved_method_of_cell_culture_system_from_eye_stalk_hepatopancreas_muscle_ovary_and_hemocytes_of_Penaeus_vannamei?f_ri=71469","dom_id":"work_7252358","summary":"Improved methods of cell culture from eye stalk, hepatopancreas, muscle, ovary, and hemocytes of shrimp (Penaeus vannamei) were established using synthetic media and shrimp muscle extract (SME). For hemocytes and ovarian cell cultures, Grace’s insect medium supplemented with 10% (v/v) fetal bovine serum and 10% SME (v/v) showed enhanced attachment and proliferation of the cells. The hemocyte and ovarian cell cultures could be maintained for 48 and 66 days, respectively, and have been sub-cultured four and six times, respectively. Both ovary and hemocyte cell cultures contained primarily epithelial-like cells. Cells derived from ovary tissue grew preferably between 26°C and 28°C with 5% CO2. Although the temperature preference of hemocyte cells was the same as ovarian cells, CO2 supplementation did not show any difference in the growth of hemocyte cells. When the shrimp were injected with lipopolysaccharide (8 μg/g of shrimp) and hemolymph was drawn 24 h post-injection, the in vitro multiplicity of hemocytes dramatically improved. The growth of eye stalk, hepatopancreas, and muscle-derived cells was much less compared to ovarian cells and hemocytes under the conditions described above. The optimal culture conditions for ovarian cells and hemocytes were also different from that for eye stalk, hepatopancreas, and muscle cell culture. The proliferation efficiencies of primary cultures of hepatopancreas, eyestalk, and muscle cells were about 30, 12, and \u003c7 d, respectively. The improved culture conditions described here, particularly for hemocytes and ovary, will be very useful for in vitro studies involving viruses infecting shrimp and in shrimp genomic studies.","downloadable_attachments":[{"id":48548723,"asset_id":7252358,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":12637212,"first_name":"Arun","last_name":"Dhar","domain_name":"independent","page_name":"DharArun","display_name":"Arun Dhar","profile_url":"https://independent.academia.edu/DharArun?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=71469","nofollow":true},{"id":173,"name":"Zoology","url":"https://www.academia.edu/Documents/in/Zoology?f_ri=71469","nofollow":true},{"id":4594,"name":"Carbon Dioxide","url":"https://www.academia.edu/Documents/in/Carbon_Dioxide?f_ri=71469","nofollow":true},{"id":37782,"name":"Cell Culture","url":"https://www.academia.edu/Documents/in/Cell_Culture?f_ri=71469","nofollow":true},{"id":48183,"name":"Lipopolysaccharide","url":"https://www.academia.edu/Documents/in/Lipopolysaccharide?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":133177,"name":"Temperature","url":"https://www.academia.edu/Documents/in/Temperature?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":315091,"name":"Hemocytes","url":"https://www.academia.edu/Documents/in/Hemocytes?f_ri=71469"},{"id":335983,"name":"Lipopolysaccharides","url":"https://www.academia.edu/Documents/in/Lipopolysaccharides?f_ri=71469"},{"id":372598,"name":"Fetal Bovine Serum","url":"https://www.academia.edu/Documents/in/Fetal_Bovine_Serum?f_ri=71469"},{"id":585385,"name":"Primary Cell Culture","url":"https://www.academia.edu/Documents/in/Primary_Cell_Culture?f_ri=71469"},{"id":780594,"name":"In Vitro Studies","url":"https://www.academia.edu/Documents/in/In_Vitro_Studies?f_ri=71469"},{"id":782254,"name":"Primary Culture","url":"https://www.academia.edu/Documents/in/Primary_Culture?f_ri=71469"},{"id":869175,"name":"Ovary","url":"https://www.academia.edu/Documents/in/Ovary?f_ri=71469"},{"id":1435468,"name":"Penaeidae","url":"https://www.academia.edu/Documents/in/Penaeidae?f_ri=71469"},{"id":1748970,"name":"Hepatopancreas","url":"https://www.academia.edu/Documents/in/Hepatopancreas?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_5439147" data-work_id="5439147" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/5439147/Immunocytochemistry_of_muscle_cytoskeletal_proteins_in_acid_maltase_deficiency">Immunocytochemistry of muscle cytoskeletal proteins in acid maltase deficiency</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Immunocytochemistry of dystrophin, spectrin, vinculin (sarcolemmaspecific proteins), and desmin (an intermediate filament protein) were investigated in 5 patients with acid maltase deficiency (AMD). One patient had infant onset, 2 had... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_5439147" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Immunocytochemistry of dystrophin, spectrin, vinculin (sarcolemmaspecific proteins), and desmin (an intermediate filament protein) were investigated in 5 patients with acid maltase deficiency (AMD). One patient had infant onset, 2 had childhood onset, and 2 had adult onset. All had a vacuolar myopathy with autophagic vacuoles containing glycogen and cytoplasmic degradation products. Dystrophin, spectrin, and vinculin were localized at the sarcolemma as in normal muscle fibers. Within the cytoplasm of many fibers, immunoreactivity for the three proteins was seen as single or multiple spots or as circular structures, which most likely corresponded to the limiting membrane of vacuoles. Desmin was overexpressed at the periphery of some vacuoles. It is plausible that, before exocytosis occurs, sarcolemma-specific proteins appear within the vacuole membrane. Vacuole immunolabeling frequently occurred in the patients with childhood and adult onset AMD, but very rarely occurred in the case with infant onset. We hypothesize that a reduced exocytosis rate might explain the infrequent vacuole immunolabeling and the early onset of the infant form of the disease. © 1994 John Wiley & Sons, Inc.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/5439147" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ab9cad51e2e5afada712988a96b733ed" rel="nofollow" data-download="{"attachment_id":49293356,"asset_id":5439147,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49293356/download_file?st=MTc0MDE2MTYyNyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="7617473" href="https://independent.academia.edu/AntonioToscano1">Antonio Toscano</a><script data-card-contents-for-user="7617473" type="text/json">{"id":7617473,"first_name":"Antonio","last_name":"Toscano","domain_name":"independent","page_name":"AntonioToscano1","display_name":"Antonio Toscano","profile_url":"https://independent.academia.edu/AntonioToscano1?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_5439147 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="5439147"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 5439147, container: ".js-paper-rank-work_5439147", }); 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$(".js-view-count[data-work-id=5439147]").text(description); $(".js-view-count-work_5439147").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_5439147").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="5439147"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12071" rel="nofollow" href="https://www.academia.edu/Documents/in/Immunohistochemistry">Immunohistochemistry</a>, <script data-card-contents-for-ri="12071" type="text/json">{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="17923" rel="nofollow" href="https://www.academia.edu/Documents/in/Autophagy">Autophagy</a>, <script data-card-contents-for-ri="17923" type="text/json">{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37895" rel="nofollow" href="https://www.academia.edu/Documents/in/Immunocytochemistry">Immunocytochemistry</a><script data-card-contents-for-ri="37895" type="text/json">{"id":37895,"name":"Immunocytochemistry","url":"https://www.academia.edu/Documents/in/Immunocytochemistry?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=5439147]'), work: {"id":5439147,"title":"Immunocytochemistry of muscle cytoskeletal proteins in acid maltase deficiency","created_at":"2013-12-15T19:48:35.836-08:00","url":"https://www.academia.edu/5439147/Immunocytochemistry_of_muscle_cytoskeletal_proteins_in_acid_maltase_deficiency?f_ri=71469","dom_id":"work_5439147","summary":"Immunocytochemistry of dystrophin, spectrin, vinculin (sarcolemmaspecific proteins), and desmin (an intermediate filament protein) were investigated in 5 patients with acid maltase deficiency (AMD). One patient had infant onset, 2 had childhood onset, and 2 had adult onset. All had a vacuolar myopathy with autophagic vacuoles containing glycogen and cytoplasmic degradation products. Dystrophin, spectrin, and vinculin were localized at the sarcolemma as in normal muscle fibers. Within the cytoplasm of many fibers, immunoreactivity for the three proteins was seen as single or multiple spots or as circular structures, which most likely corresponded to the limiting membrane of vacuoles. Desmin was overexpressed at the periphery of some vacuoles. It is plausible that, before exocytosis occurs, sarcolemma-specific proteins appear within the vacuole membrane. Vacuole immunolabeling frequently occurred in the patients with childhood and adult onset AMD, but very rarely occurred in the case with infant onset. We hypothesize that a reduced exocytosis rate might explain the infrequent vacuole immunolabeling and the early onset of the infant form of the disease. © 1994 John Wiley \u0026 Sons, Inc.","downloadable_attachments":[{"id":49293356,"asset_id":5439147,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":7617473,"first_name":"Antonio","last_name":"Toscano","domain_name":"independent","page_name":"AntonioToscano1","display_name":"Antonio Toscano","profile_url":"https://independent.academia.edu/AntonioToscano1?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=71469","nofollow":true},{"id":17923,"name":"Autophagy","url":"https://www.academia.edu/Documents/in/Autophagy?f_ri=71469","nofollow":true},{"id":37895,"name":"Immunocytochemistry","url":"https://www.academia.edu/Documents/in/Immunocytochemistry?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=71469"},{"id":230682,"name":"Spectrin","url":"https://www.academia.edu/Documents/in/Spectrin?f_ri=71469"},{"id":557707,"name":"Exocytosis","url":"https://www.academia.edu/Documents/in/Exocytosis?f_ri=71469"},{"id":911036,"name":"Dystrophin","url":"https://www.academia.edu/Documents/in/Dystrophin?f_ri=71469"},{"id":2277447,"name":"Vinculin","url":"https://www.academia.edu/Documents/in/Vinculin?f_ri=71469"},{"id":2428330,"name":"Vacuoles","url":"https://www.academia.edu/Documents/in/Vacuoles?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_6259867" data-work_id="6259867" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/6259867/Direction_Specific_Diaphyseal_Geometry_and_Mineral_Mass_Distribution_of_Tibia_and_Fibula_A_pQCT_Study_of_Female_Athletes_Representing_Different_Exercise_Loading_Types">Direction-Specific Diaphyseal Geometry and Mineral Mass Distribution of Tibia and Fibula: A pQCT Study of Female Athletes Representing Different Exercise Loading Types</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Bones adapt to prevalent loading, which comprises mainly forces caused by muscle contractions. Therefore, we hypothesized that similar associations would be observed between neuromuscular performance and rigidity of bones located in the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_6259867" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Bones adapt to prevalent loading, which comprises mainly forces caused by muscle contractions. Therefore, we hypothesized that similar associations would be observed between neuromuscular performance and rigidity of bones located in the same body segment. These associations were assessed among 221 premenopausal women representing athletes in high-impact, odd-impact, high-magnitude, repetitive low-impact, and repetitive nonimpact sports and physically active referents aged 17–40 years. The whole group mean age and body mass were 23 (5) and 63 (9) kg, respectively. Bone cross sections at the tibial and fibular mid-diaphysis were assessed with peripheral quantitative computed tomography (pQCT). Density-weighted polar section modulus (SSI) and minimal and maximal cross-sectional moments of inertia (Imin, Imax) were analyzed. Bone morphology was described as the Imax/Imin ratio. Neuromuscular performance was assessed by maximal power during countermovement jump (CMJ). Tibial SSI was 31% higher in the high-impact, 19% in the odd-impact, and 30% in the repetitive low-impact groups compared with the reference group (P < 0.005). Only the high-impact group differed from the referents in fibular SSI (17%, P < 0.005). Tibial morphology differed between groups (P = 0.001), but fibular morphology did not (P = 0.247). The bone-by-group interaction was highly significant (P < 0.001). After controlling for height, weight, and age, the CMJ peak power correlated moderately with tibial SSI (r = 0.31, P < 0.001) but not with fibular SSI (r = 0.069, P = 0.313). In conclusion, observed differences in the association between neuromuscular performance and tibial and fibular traits suggest that the tibia and fibula experience different loading environments despite their anatomical vicinity.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/6259867" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e4a0e4bf4a2c0d8d15158df3d36c925d" rel="nofollow" data-download="{"attachment_id":48943297,"asset_id":6259867,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48943297/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="9651270" href="https://deakin.academia.edu/TimoRantalainen">Timo Rantalainen</a><script data-card-contents-for-user="9651270" type="text/json">{"id":9651270,"first_name":"Timo","last_name":"Rantalainen","domain_name":"deakin","page_name":"TimoRantalainen","display_name":"Timo Rantalainen","profile_url":"https://deakin.academia.edu/TimoRantalainen?f_ri=71469","photo":"https://0.academia-photos.com/9651270/49107881/37077618/s65_timo.rantalainen.png"}</script></span></span></li><li class="js-paper-rank-work_6259867 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="6259867"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 6259867, container: ".js-paper-rank-work_6259867", }); 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$(".js-view-count[data-work-id=6259867]").text(description); $(".js-view-count-work_6259867").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_6259867").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="6259867"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1131" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9112" rel="nofollow" href="https://www.academia.edu/Documents/in/Physical_Activity">Physical Activity</a>, <script data-card-contents-for-ri="9112" type="text/json">{"id":9112,"name":"Physical Activity","url":"https://www.academia.edu/Documents/in/Physical_Activity?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a><script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=6259867]'), work: {"id":6259867,"title":"Direction-Specific Diaphyseal Geometry and Mineral Mass Distribution of Tibia and Fibula: A pQCT Study of Female Athletes Representing Different Exercise Loading Types","created_at":"2014-03-02T07:54:16.887-08:00","url":"https://www.academia.edu/6259867/Direction_Specific_Diaphyseal_Geometry_and_Mineral_Mass_Distribution_of_Tibia_and_Fibula_A_pQCT_Study_of_Female_Athletes_Representing_Different_Exercise_Loading_Types?f_ri=71469","dom_id":"work_6259867","summary":"Bones adapt to prevalent loading, which comprises mainly forces caused by muscle contractions. Therefore, we hypothesized that similar associations would be observed between neuromuscular performance and rigidity of bones located in the same body segment. These associations were assessed among 221 premenopausal women representing athletes in high-impact, odd-impact, high-magnitude, repetitive low-impact, and repetitive nonimpact sports and physically active referents aged 17–40 years. The whole group mean age and body mass were 23 (5) and 63 (9) kg, respectively. Bone cross sections at the tibial and fibular mid-diaphysis were assessed with peripheral quantitative computed tomography (pQCT). Density-weighted polar section modulus (SSI) and minimal and maximal cross-sectional moments of inertia (Imin, Imax) were analyzed. Bone morphology was described as the Imax/Imin ratio. Neuromuscular performance was assessed by maximal power during countermovement jump (CMJ). Tibial SSI was 31% higher in the high-impact, 19% in the odd-impact, and 30% in the repetitive low-impact groups compared with the reference group (P \u003c 0.005). Only the high-impact group differed from the referents in fibular SSI (17%, P \u003c 0.005). Tibial morphology differed between groups (P = 0.001), but fibular morphology did not (P = 0.247). The bone-by-group interaction was highly significant (P \u003c 0.001). After controlling for height, weight, and age, the CMJ peak power correlated moderately with tibial SSI (r = 0.31, P \u003c 0.001) but not with fibular SSI (r = 0.069, P = 0.313). In conclusion, observed differences in the association between neuromuscular performance and tibial and fibular traits suggest that the tibia and fibula experience different loading environments despite their anatomical vicinity.","downloadable_attachments":[{"id":48943297,"asset_id":6259867,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":9651270,"first_name":"Timo","last_name":"Rantalainen","domain_name":"deakin","page_name":"TimoRantalainen","display_name":"Timo Rantalainen","profile_url":"https://deakin.academia.edu/TimoRantalainen?f_ri=71469","photo":"https://0.academia-photos.com/9651270/49107881/37077618/s65_timo.rantalainen.png"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=71469","nofollow":true},{"id":9112,"name":"Physical Activity","url":"https://www.academia.edu/Documents/in/Physical_Activity?f_ri=71469","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":85893,"name":"Fibula","url":"https://www.academia.edu/Documents/in/Fibula?f_ri=71469"},{"id":85903,"name":"Tibia","url":"https://www.academia.edu/Documents/in/Tibia?f_ri=71469"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":139532,"name":"Bone Density","url":"https://www.academia.edu/Documents/in/Bone_Density?f_ri=71469"},{"id":219568,"name":"Athletes","url":"https://www.academia.edu/Documents/in/Athletes?f_ri=71469"},{"id":228526,"name":"Calcified tissue","url":"https://www.academia.edu/Documents/in/Calcified_tissue?f_ri=71469"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469"},{"id":295232,"name":"Premenopausal women","url":"https://www.academia.edu/Documents/in/Premenopausal_women?f_ri=71469"},{"id":397456,"name":"Body Mass","url":"https://www.academia.edu/Documents/in/Body_Mass?f_ri=71469"},{"id":404000,"name":"Cross Section","url":"https://www.academia.edu/Documents/in/Cross_Section?f_ri=71469"},{"id":420676,"name":"Group Interaction","url":"https://www.academia.edu/Documents/in/Group_Interaction?f_ri=71469"},{"id":516545,"name":"Peripheral Quantitative Computed Tomography","url":"https://www.academia.edu/Documents/in/Peripheral_Quantitative_Computed_Tomography?f_ri=71469"},{"id":552629,"name":"Moment of Inertia","url":"https://www.academia.edu/Documents/in/Moment_of_Inertia?f_ri=71469"},{"id":556021,"name":"Muscle contraction","url":"https://www.academia.edu/Documents/in/Muscle_contraction?f_ri=71469"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=71469"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62291755" data-work_id="62291755" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62291755/Effect_of_Creatine_Supplementation_on_Muscle_Capacity_in_Individuals_with_Multiple_Sclerosis">Effect of Creatine Supplementation on Muscle Capacity in Individuals with Multiple Sclerosis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">There has been interest in the use of exogenous creatine (Cr) as an adjunct treatment for neurological disorders. Creatine enhances bouts of activity through augmenting phosphocreatine for increased synthesis of ATP; however, multiple... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_62291755" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">There has been interest in the use of exogenous creatine (Cr) as an adjunct treatment for neurological disorders. Creatine enhances bouts of activity through augmenting phosphocreatine for increased synthesis of ATP; however, multiple sclerosis (MS) individuals suffering from muscle weakness have not been shown to improve muscle work after 5 days of Cr supplementation. This study's purpose was to determine whether the extended duration would increase muscle capacity. In a double-blind, crossover trial, with a 3-week washout period, eleven MS subjects were randomly assigned to either Cr (5 g 4/day, day 1-7: 2.5 g 2/day, day 8-14) or placebo groups for two 14-day periods. Biodex Dynamometer recorded total work and power over three bouts of 30 maximal knee extensions and flexions. Total work was nonsignificant with Cr for knee extension (pretest 1277.7</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62291755" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="47bcb6868340891970875e39ab9d7a8c" rel="nofollow" data-download="{"attachment_id":75106611,"asset_id":62291755,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75106611/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33499669" href="https://independent.academia.edu/NancyCotugna">Nancy Cotugna</a><script data-card-contents-for-user="33499669" type="text/json">{"id":33499669,"first_name":"Nancy","last_name":"Cotugna","domain_name":"independent","page_name":"NancyCotugna","display_name":"Nancy Cotugna","profile_url":"https://independent.academia.edu/NancyCotugna?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_62291755 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62291755"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62291755, container: ".js-paper-rank-work_62291755", }); 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$(".js-view-count[data-work-id=62291755]").text(description); $(".js-view-count-work_62291755").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62291755").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="62291755"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1907" rel="nofollow" href="https://www.academia.edu/Documents/in/Nutrition">Nutrition</a>, <script data-card-contents-for-ri="1907" type="text/json">{"id":1907,"name":"Nutrition","url":"https://www.academia.edu/Documents/in/Nutrition?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3097" rel="nofollow" href="https://www.academia.edu/Documents/in/Multiple_sclerosis">Multiple sclerosis</a>, <script data-card-contents-for-ri="3097" type="text/json">{"id":3097,"name":"Multiple sclerosis","url":"https://www.academia.edu/Documents/in/Multiple_sclerosis?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="13777" rel="nofollow" href="https://www.academia.edu/Documents/in/Creatine">Creatine</a>, <script data-card-contents-for-ri="13777" type="text/json">{"id":13777,"name":"Creatine","url":"https://www.academia.edu/Documents/in/Creatine?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44530" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle_strength">Muscle strength</a><script data-card-contents-for-ri="44530" type="text/json">{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=62291755]'), work: {"id":62291755,"title":"Effect of Creatine Supplementation on Muscle Capacity in Individuals with Multiple Sclerosis","created_at":"2021-11-24T12:58:12.844-08:00","url":"https://www.academia.edu/62291755/Effect_of_Creatine_Supplementation_on_Muscle_Capacity_in_Individuals_with_Multiple_Sclerosis?f_ri=71469","dom_id":"work_62291755","summary":"There has been interest in the use of exogenous creatine (Cr) as an adjunct treatment for neurological disorders. Creatine enhances bouts of activity through augmenting phosphocreatine for increased synthesis of ATP; however, multiple sclerosis (MS) individuals suffering from muscle weakness have not been shown to improve muscle work after 5 days of Cr supplementation. This study's purpose was to determine whether the extended duration would increase muscle capacity. In a double-blind, crossover trial, with a 3-week washout period, eleven MS subjects were randomly assigned to either Cr (5 g 4/day, day 1-7: 2.5 g 2/day, day 8-14) or placebo groups for two 14-day periods. Biodex Dynamometer recorded total work and power over three bouts of 30 maximal knee extensions and flexions. Total work was nonsignificant with Cr for knee extension (pretest 1277.7","downloadable_attachments":[{"id":75106611,"asset_id":62291755,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33499669,"first_name":"Nancy","last_name":"Cotugna","domain_name":"independent","page_name":"NancyCotugna","display_name":"Nancy Cotugna","profile_url":"https://independent.academia.edu/NancyCotugna?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1907,"name":"Nutrition","url":"https://www.academia.edu/Documents/in/Nutrition?f_ri=71469","nofollow":true},{"id":3097,"name":"Multiple sclerosis","url":"https://www.academia.edu/Documents/in/Multiple_sclerosis?f_ri=71469","nofollow":true},{"id":13777,"name":"Creatine","url":"https://www.academia.edu/Documents/in/Creatine?f_ri=71469","nofollow":true},{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":78189,"name":"Knee","url":"https://www.academia.edu/Documents/in/Knee?f_ri=71469"},{"id":112275,"name":"Resistance Training","url":"https://www.academia.edu/Documents/in/Resistance_Training?f_ri=71469"},{"id":152562,"name":"Dietary Supplements","url":"https://www.academia.edu/Documents/in/Dietary_Supplements?f_ri=71469"},{"id":357849,"name":"Skeletal Muscle","url":"https://www.academia.edu/Documents/in/Skeletal_Muscle?f_ri=71469"},{"id":1145265,"name":"Knee Joint","url":"https://www.academia.edu/Documents/in/Knee_Joint?f_ri=71469"},{"id":1146830,"name":"Cross-Over Studies","url":"https://www.academia.edu/Documents/in/Cross-Over_Studies?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_56115130" data-work_id="56115130" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/56115130/Platelet_rich_plasma_PRP_Methodological_aspects_and_clinical_applications">Platelet-rich plasma (PRP): Methodological aspects and clinical applications</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The clinical use of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors and in the secretion of proteins which are able to maximize the healing process at the cellular level. Since PRP is an... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_56115130" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The clinical use of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors and in the secretion of proteins which are able to maximize the healing process at the cellular level. Since PRP is an autologous biologic material, it involves a minimum risk of immune reactions and transmission of infectious and contagious diseases, and it has been widely used for the recovery of musculoskeletal lesions. Despite the great potential for applicability, the implementation of the therapeutic employment of PRP as a clinical alternative has become difficult, due to the lack of studies related to the standardization of the techniques and/or insufficient description of the adopted procedures. Therefore, it is required establish standard criteria to be followed for obtaining a PRP of high quality, as well as a larger number of studies which should establish the proper concentration of platelets for the different clinical conditions. In this context, the purpose of this review is to discuss some methodological aspects used for achieving the PRP, as well as to discuss the bioactive properties of PRP, and to point out its therapeutic use in different fields of regenerative medicine.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/56115130" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b358a3b4441ee4ca08521214d98bd314" rel="nofollow" data-download="{"attachment_id":71660475,"asset_id":56115130,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/71660475/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5917180" href="https://unesp.academia.edu/Jo%C3%A3oTadeuRibeiroPaes">João Tadeu Ribeiro-Paes</a><script data-card-contents-for-user="5917180" type="text/json">{"id":5917180,"first_name":"João Tadeu","last_name":"Ribeiro-Paes","domain_name":"unesp","page_name":"JoãoTadeuRibeiroPaes","display_name":"João Tadeu Ribeiro-Paes","profile_url":"https://unesp.academia.edu/Jo%C3%A3oTadeuRibeiroPaes?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_56115130 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="56115130"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 56115130, container: ".js-paper-rank-work_56115130", }); 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$(".js-view-count[data-work-id=56115130]").text(description); $(".js-view-count-work_56115130").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_56115130").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="56115130"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="91390" rel="nofollow" href="https://www.academia.edu/Documents/in/Platelets">Platelets</a>, <script data-card-contents-for-ri="91390" type="text/json">{"id":91390,"name":"Platelets","url":"https://www.academia.edu/Documents/in/Platelets?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="128557" rel="nofollow" href="https://www.academia.edu/Documents/in/Tendinopathy">Tendinopathy</a>, <script data-card-contents-for-ri="128557" type="text/json">{"id":128557,"name":"Tendinopathy","url":"https://www.academia.edu/Documents/in/Tendinopathy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=56115130]'), work: {"id":56115130,"title":"Platelet-rich plasma (PRP): Methodological aspects and clinical applications","created_at":"2021-10-06T19:25:05.901-07:00","url":"https://www.academia.edu/56115130/Platelet_rich_plasma_PRP_Methodological_aspects_and_clinical_applications?f_ri=71469","dom_id":"work_56115130","summary":"The clinical use of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors and in the secretion of proteins which are able to maximize the healing process at the cellular level. Since PRP is an autologous biologic material, it involves a minimum risk of immune reactions and transmission of infectious and contagious diseases, and it has been widely used for the recovery of musculoskeletal lesions. Despite the great potential for applicability, the implementation of the therapeutic employment of PRP as a clinical alternative has become difficult, due to the lack of studies related to the standardization of the techniques and/or insufficient description of the adopted procedures. Therefore, it is required establish standard criteria to be followed for obtaining a PRP of high quality, as well as a larger number of studies which should establish the proper concentration of platelets for the different clinical conditions. In this context, the purpose of this review is to discuss some methodological aspects used for achieving the PRP, as well as to discuss the bioactive properties of PRP, and to point out its therapeutic use in different fields of regenerative medicine.","downloadable_attachments":[{"id":71660475,"asset_id":56115130,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5917180,"first_name":"João Tadeu","last_name":"Ribeiro-Paes","domain_name":"unesp","page_name":"JoãoTadeuRibeiroPaes","display_name":"João Tadeu Ribeiro-Paes","profile_url":"https://unesp.academia.edu/Jo%C3%A3oTadeuRibeiroPaes?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":91390,"name":"Platelets","url":"https://www.academia.edu/Documents/in/Platelets?f_ri=71469","nofollow":true},{"id":128557,"name":"Tendinopathy","url":"https://www.academia.edu/Documents/in/Tendinopathy?f_ri=71469","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469","nofollow":true},{"id":353724,"name":"Platelet Rich Plasma","url":"https://www.academia.edu/Documents/in/Platelet_Rich_Plasma?f_ri=71469"},{"id":840665,"name":"Biological Factors","url":"https://www.academia.edu/Documents/in/Biological_Factors?f_ri=71469"},{"id":2721079,"name":"Bone Diseases","url":"https://www.academia.edu/Documents/in/Bone_Diseases?f_ri=71469"},{"id":2982788,"name":"Blood component transfusion","url":"https://www.academia.edu/Documents/in/Blood_component_transfusion?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48695394" data-work_id="48695394" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48695394/Influence_of_carbon_monoxide_in_package_atmospheres_containing_oxygen_on_colour_reducing_activity_and_oxygen_consumption_of_five_bovine_muscles">Influence of carbon monoxide in package atmospheres containing oxygen on colour, reducing activity, and oxygen consumption of five bovine muscles</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Steaks from five bovine muscles [psoas major (PM), longissimus lumborum (LL), deep semimembranosus (DSM), superficial semimembranosus (SSM), and semitendinosus (ST)] were packaged in atmospheres containing 20% or 80% oxygen, with and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48695394" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Steaks from five bovine muscles [psoas major (PM), longissimus lumborum (LL), deep semimembranosus (DSM), superficial semimembranosus (SSM), and semitendinosus (ST)] were packaged in atmospheres containing 20% or 80% oxygen, with and without 0.4% carbon monoxide. Steaks were evaluated on d 0, 4, and 7 of retail display for instrumental (CIE L * , a * , and b *) and visual colour, total-and metmyoglobin-reducing activity, and oxygen consumption rate. Combining carbon monoxide with either oxygen level had no effect (P > 0.05) on any measured attribute. Using higher oxygen levels increased colour stability and reduced variability (P < 0.05) among muscles for all measured attributes. In general, colour stability and reducing activity for the muscles were LL > ST > SSM > PM > DSM. Including 0.4% carbon monoxide with 20% or 80% oxygen may not have impacted colour, due to preferential formation of oxymyoglobin, rather than carboxymyoglobin, at these oxygen levels.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48695394" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ab2fb21bd680b47308ce332e4cbbe363" rel="nofollow" data-download="{"attachment_id":67175443,"asset_id":48695394,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67175443/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46784766" href="https://ksu.academia.edu/MelvinHunt">Melvin Hunt</a><script data-card-contents-for-user="46784766" type="text/json">{"id":46784766,"first_name":"Melvin","last_name":"Hunt","domain_name":"ksu","page_name":"MelvinHunt","display_name":"Melvin Hunt","profile_url":"https://ksu.academia.edu/MelvinHunt?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_48695394 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48695394"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48695394, container: ".js-paper-rank-work_48695394", }); });</script></li><li class="js-percentile-work_48695394 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 48695394; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_48695394"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_48695394 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="48695394"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 48695394; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=48695394]").text(description); $(".js-view-count-work_48695394").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_48695394").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="48695394"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="72" rel="nofollow" href="https://www.academia.edu/Documents/in/Chemical_Engineering">Chemical Engineering</a>, <script data-card-contents-for-ri="72" type="text/json">{"id":72,"name":"Chemical Engineering","url":"https://www.academia.edu/Documents/in/Chemical_Engineering?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1036" rel="nofollow" href="https://www.academia.edu/Documents/in/Meat_Science">Meat Science</a>, <script data-card-contents-for-ri="1036" type="text/json">{"id":1036,"name":"Meat Science","url":"https://www.academia.edu/Documents/in/Meat_Science?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="5021" rel="nofollow" href="https://www.academia.edu/Documents/in/Packaging">Packaging</a>, <script data-card-contents-for-ri="5021" type="text/json">{"id":5021,"name":"Packaging","url":"https://www.academia.edu/Documents/in/Packaging?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="29980" rel="nofollow" href="https://www.academia.edu/Documents/in/Animal_Production">Animal Production</a><script data-card-contents-for-ri="29980" type="text/json">{"id":29980,"name":"Animal Production","url":"https://www.academia.edu/Documents/in/Animal_Production?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=48695394]'), work: {"id":48695394,"title":"Influence of carbon monoxide in package atmospheres containing oxygen on colour, reducing activity, and oxygen consumption of five bovine muscles","created_at":"2021-05-05T05:23:51.614-07:00","url":"https://www.academia.edu/48695394/Influence_of_carbon_monoxide_in_package_atmospheres_containing_oxygen_on_colour_reducing_activity_and_oxygen_consumption_of_five_bovine_muscles?f_ri=71469","dom_id":"work_48695394","summary":"Steaks from five bovine muscles [psoas major (PM), longissimus lumborum (LL), deep semimembranosus (DSM), superficial semimembranosus (SSM), and semitendinosus (ST)] were packaged in atmospheres containing 20% or 80% oxygen, with and without 0.4% carbon monoxide. Steaks were evaluated on d 0, 4, and 7 of retail display for instrumental (CIE L * , a * , and b *) and visual colour, total-and metmyoglobin-reducing activity, and oxygen consumption rate. Combining carbon monoxide with either oxygen level had no effect (P \u003e 0.05) on any measured attribute. Using higher oxygen levels increased colour stability and reduced variability (P \u003c 0.05) among muscles for all measured attributes. In general, colour stability and reducing activity for the muscles were LL \u003e ST \u003e SSM \u003e PM \u003e DSM. Including 0.4% carbon monoxide with 20% or 80% oxygen may not have impacted colour, due to preferential formation of oxymyoglobin, rather than carboxymyoglobin, at these oxygen levels.","downloadable_attachments":[{"id":67175443,"asset_id":48695394,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46784766,"first_name":"Melvin","last_name":"Hunt","domain_name":"ksu","page_name":"MelvinHunt","display_name":"Melvin Hunt","profile_url":"https://ksu.academia.edu/MelvinHunt?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":72,"name":"Chemical Engineering","url":"https://www.academia.edu/Documents/in/Chemical_Engineering?f_ri=71469","nofollow":true},{"id":1036,"name":"Meat Science","url":"https://www.academia.edu/Documents/in/Meat_Science?f_ri=71469","nofollow":true},{"id":5021,"name":"Packaging","url":"https://www.academia.edu/Documents/in/Packaging?f_ri=71469","nofollow":true},{"id":29980,"name":"Animal Production","url":"https://www.academia.edu/Documents/in/Animal_Production?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":71905,"name":"Carbon Monoxide","url":"https://www.academia.edu/Documents/in/Carbon_Monoxide?f_ri=71469"},{"id":115368,"name":"Colour","url":"https://www.academia.edu/Documents/in/Colour?f_ri=71469"},{"id":474134,"name":"Conditioning","url":"https://www.academia.edu/Documents/in/Conditioning?f_ri=71469"},{"id":569759,"name":"Modified atmosphere packaging","url":"https://www.academia.edu/Documents/in/Modified_atmosphere_packaging?f_ri=71469"},{"id":573653,"name":"Food Sciences","url":"https://www.academia.edu/Documents/in/Food_Sciences?f_ri=71469"},{"id":1193624,"name":"Oxygen Consumption","url":"https://www.academia.edu/Documents/in/Oxygen_Consumption?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48600461" data-work_id="48600461" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48600461/Stretch_shortening_cycle_characteristics_during_vertical_jumps_carried_out_with_small_and_large_range_of_motion">Stretch-shortening cycle characteristics during vertical jumps carried out with small and large range of motion</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In the present study we investigated kinematical characteristics of the knee and ankle extensors to estimate the length change properties of the contractile and the passive elements in countermovement jumps (CMJ) and drop jumps (DJ)... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48600461" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In the present study we investigated kinematical characteristics of the knee and ankle extensors to estimate the length change properties of the contractile and the passive elements in countermovement jumps (CMJ) and drop jumps (DJ) performed with small (40°) and large (80°) range of joint motion (SRM and LRM). At SRM the accelerations at maximal muscle lengths compared with the last phase of joint flexion were greater for the gastrocnemius and the soleus (124.9% and 79.4%) and also were greater than at the beginning of joint extension, while no difference was measured at LRM. The differences suggest that at LRM the length change of the serial passive elements from the end of joint flexion to the beginning of joint extension is minimal and simultaneously the length change of the contractile elements is significant, but at SRM -especially in the plantar flexors -the length change of the contractile elements is minimal while in the passive elements significant. It can be presumed that for SRM at the end of joint flexion significant elastic energy is stored and at the beginning of joint extension reused, while for LRM elastic energy storage is not dominant.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48600461" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="059e25cc74f492f0bde4b9340a21b529" rel="nofollow" data-download="{"attachment_id":67128218,"asset_id":48600461,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67128218/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5287997" href="https://independent.academia.edu/JozsefTihanyi">Jozsef Tihanyi</a><script data-card-contents-for-user="5287997" type="text/json">{"id":5287997,"first_name":"Jozsef","last_name":"Tihanyi","domain_name":"independent","page_name":"JozsefTihanyi","display_name":"Jozsef Tihanyi","profile_url":"https://independent.academia.edu/JozsefTihanyi?f_ri=71469","photo":"https://0.academia-photos.com/5287997/160926175/150638785/s65_jozsef.tihanyi.jpeg"}</script></span></span></li><li class="js-paper-rank-work_48600461 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48600461"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48600461, container: ".js-paper-rank-work_48600461", }); });</script></li><li class="js-percentile-work_48600461 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 48600461; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_48600461"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_48600461 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="48600461"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 48600461; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=48600461]").text(description); $(".js-view-count-work_48600461").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_48600461").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="48600461"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="48904" rel="nofollow" href="https://www.academia.edu/Documents/in/Elasticity">Elasticity</a>, <script data-card-contents-for-ri="48904" type="text/json">{"id":48904,"name":"Elasticity","url":"https://www.academia.edu/Documents/in/Elasticity?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="78189" rel="nofollow" href="https://www.academia.edu/Documents/in/Knee">Knee</a><script data-card-contents-for-ri="78189" type="text/json">{"id":78189,"name":"Knee","url":"https://www.academia.edu/Documents/in/Knee?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=48600461]'), work: {"id":48600461,"title":"Stretch-shortening cycle characteristics during vertical jumps carried out with small and large range of motion","created_at":"2021-05-05T00:15:55.997-07:00","url":"https://www.academia.edu/48600461/Stretch_shortening_cycle_characteristics_during_vertical_jumps_carried_out_with_small_and_large_range_of_motion?f_ri=71469","dom_id":"work_48600461","summary":"In the present study we investigated kinematical characteristics of the knee and ankle extensors to estimate the length change properties of the contractile and the passive elements in countermovement jumps (CMJ) and drop jumps (DJ) performed with small (40°) and large (80°) range of joint motion (SRM and LRM). At SRM the accelerations at maximal muscle lengths compared with the last phase of joint flexion were greater for the gastrocnemius and the soleus (124.9% and 79.4%) and also were greater than at the beginning of joint extension, while no difference was measured at LRM. The differences suggest that at LRM the length change of the serial passive elements from the end of joint flexion to the beginning of joint extension is minimal and simultaneously the length change of the contractile elements is significant, but at SRM -especially in the plantar flexors -the length change of the contractile elements is minimal while in the passive elements significant. It can be presumed that for SRM at the end of joint flexion significant elastic energy is stored and at the beginning of joint extension reused, while for LRM elastic energy storage is not dominant.","downloadable_attachments":[{"id":67128218,"asset_id":48600461,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5287997,"first_name":"Jozsef","last_name":"Tihanyi","domain_name":"independent","page_name":"JozsefTihanyi","display_name":"Jozsef Tihanyi","profile_url":"https://independent.academia.edu/JozsefTihanyi?f_ri=71469","photo":"https://0.academia-photos.com/5287997/160926175/150638785/s65_jozsef.tihanyi.jpeg"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":48904,"name":"Elasticity","url":"https://www.academia.edu/Documents/in/Elasticity?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":78189,"name":"Knee","url":"https://www.academia.edu/Documents/in/Knee?f_ri=71469","nofollow":true},{"id":84745,"name":"Movement","url":"https://www.academia.edu/Documents/in/Movement?f_ri=71469"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":201957,"name":"Acceleration","url":"https://www.academia.edu/Documents/in/Acceleration?f_ri=71469"},{"id":556021,"name":"Muscle contraction","url":"https://www.academia.edu/Documents/in/Muscle_contraction?f_ri=71469"},{"id":670043,"name":"Joints","url":"https://www.academia.edu/Documents/in/Joints?f_ri=71469"},{"id":717129,"name":"Energy Transfer","url":"https://www.academia.edu/Documents/in/Energy_Transfer?f_ri=71469"},{"id":740993,"name":"Ankle Joint","url":"https://www.academia.edu/Documents/in/Ankle_Joint?f_ri=71469"},{"id":1028191,"name":"Ankle","url":"https://www.academia.edu/Documents/in/Ankle?f_ri=71469"},{"id":1145265,"name":"Knee Joint","url":"https://www.academia.edu/Documents/in/Knee_Joint?f_ri=71469"},{"id":1902100,"name":"Biomechanical Phenomena","url":"https://www.academia.edu/Documents/in/Biomechanical_Phenomena?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48046542" data-work_id="48046542" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48046542/Functional_aspects_of_the_coracoclavicular_space">Functional aspects of the coracoclavicular space</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background The coracoclavicular joint has been described as an articulation found inconstantly between the coracoid process and clavicle. We often observe a small space bordered by the fascia which covers the anterior surface of the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48046542" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background The coracoclavicular joint has been described as an articulation found inconstantly between the coracoid process and clavicle. We often observe a small space bordered by the fascia which covers the anterior surface of the subclavius muscle and the coracoclavicular ligament. The aim of this study was to observe the space in detail and to discuss the functional role of the coracoclavicular joint. Materials and methods Sixteen shoulder girdles from eight Japanese cadavers were used in this study. The scapula, clavicle, and anterior half of the Wrst rib were extracted en bloc together with the subclavius muscle and the surrounding fascia. After observing the motion of the scapula and clavicle, we investigated macroscopically the attachments of the coracoclavicular ligaments and the subclavius muscle, and the extension of the fascia. Results The fascia divided laterally into two sheets: the anterior sheet attached to the trapezoid ligament and the posterior to the conoid ligament. Among the two sheets, the coracoclavicular ligaments, coracoid process, and clavicle, a small space was observed. This small space can be recognized as a part of the coracoclavicular joint. When manually moving the inferior angle of the scapula with the sternal end of the clavicle Wxed, we observed that the clavicle collided with the trapezoid ligament on the superior surface of the coracoid process within the space and that the scapular motion was restricted by this collision. Conclusion The coracoclavicular joint could be much more recognizable than in previous papers and play an important role in the normal function of the shoulder joint. Level of evidence Basic science study.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48046542" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2658cc5708890bcfcee382743505fb6a" rel="nofollow" data-download="{"attachment_id":66862034,"asset_id":48046542,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/66862034/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="24822141" href="https://independent.academia.edu/KeiichiAkita">Keiichi Akita</a><script data-card-contents-for-user="24822141" type="text/json">{"id":24822141,"first_name":"Keiichi","last_name":"Akita","domain_name":"independent","page_name":"KeiichiAkita","display_name":"Keiichi Akita","profile_url":"https://independent.academia.edu/KeiichiAkita?f_ri=71469","photo":"https://0.academia-photos.com/24822141/6715041/7585430/s65_keiichi.akita.jpg_oh_c735e5ca149e7dfc73b1135458c8bbd6_oe_5535ba68___gda___1433340544_af5852cc702b93a56710e058b663d97d"}</script></span></span></li><li class="js-paper-rank-work_48046542 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48046542"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48046542, container: ".js-paper-rank-work_48046542", }); });</script></li><li class="js-percentile-work_48046542 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 48046542; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_48046542"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_48046542 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="48046542"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 48046542; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=48046542]").text(description); $(".js-view-count-work_48046542").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_48046542").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="48046542"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="647" rel="nofollow" href="https://www.academia.edu/Documents/in/Surgery">Surgery</a>, <script data-card-contents-for-ri="647" type="text/json">{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8942" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment">Treatment</a>, <script data-card-contents-for-ri="8942" type="text/json">{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=48046542]'), work: {"id":48046542,"title":"Functional aspects of the coracoclavicular space","created_at":"2021-05-03T23:50:58.010-07:00","url":"https://www.academia.edu/48046542/Functional_aspects_of_the_coracoclavicular_space?f_ri=71469","dom_id":"work_48046542","summary":"Background The coracoclavicular joint has been described as an articulation found inconstantly between the coracoid process and clavicle. We often observe a small space bordered by the fascia which covers the anterior surface of the subclavius muscle and the coracoclavicular ligament. The aim of this study was to observe the space in detail and to discuss the functional role of the coracoclavicular joint. Materials and methods Sixteen shoulder girdles from eight Japanese cadavers were used in this study. The scapula, clavicle, and anterior half of the Wrst rib were extracted en bloc together with the subclavius muscle and the surrounding fascia. After observing the motion of the scapula and clavicle, we investigated macroscopically the attachments of the coracoclavicular ligaments and the subclavius muscle, and the extension of the fascia. Results The fascia divided laterally into two sheets: the anterior sheet attached to the trapezoid ligament and the posterior to the conoid ligament. Among the two sheets, the coracoclavicular ligaments, coracoid process, and clavicle, a small space was observed. This small space can be recognized as a part of the coracoclavicular joint. When manually moving the inferior angle of the scapula with the sternal end of the clavicle Wxed, we observed that the clavicle collided with the trapezoid ligament on the superior surface of the coracoid process within the space and that the scapular motion was restricted by this collision. Conclusion The coracoclavicular joint could be much more recognizable than in previous papers and play an important role in the normal function of the shoulder joint. Level of evidence Basic science study.","downloadable_attachments":[{"id":66862034,"asset_id":48046542,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":24822141,"first_name":"Keiichi","last_name":"Akita","domain_name":"independent","page_name":"KeiichiAkita","display_name":"Keiichi Akita","profile_url":"https://independent.academia.edu/KeiichiAkita?f_ri=71469","photo":"https://0.academia-photos.com/24822141/6715041/7585430/s65_keiichi.akita.jpg_oh_c735e5ca149e7dfc73b1135458c8bbd6_oe_5535ba68___gda___1433340544_af5852cc702b93a56710e058b663d97d"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=71469","nofollow":true},{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=71469","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=71469","nofollow":true},{"id":29487,"name":"Space","url":"https://www.academia.edu/Documents/in/Space?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":119116,"name":"Clavicle","url":"https://www.academia.edu/Documents/in/Clavicle?f_ri=71469"},{"id":129473,"name":"Fascia","url":"https://www.academia.edu/Documents/in/Fascia?f_ri=71469"},{"id":186234,"name":"Medical Physiology","url":"https://www.academia.edu/Documents/in/Medical_Physiology?f_ri=71469"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=71469"},{"id":534656,"name":"Joint","url":"https://www.academia.edu/Documents/in/Joint?f_ri=71469"},{"id":990519,"name":"Ligaments","url":"https://www.academia.edu/Documents/in/Ligaments?f_ri=71469"},{"id":1115730,"name":"Articulation","url":"https://www.academia.edu/Documents/in/Articulation?f_ri=71469"},{"id":2044714,"name":"Scapula","url":"https://www.academia.edu/Documents/in/Scapula?f_ri=71469"},{"id":2558521,"name":"Shoulder joint","url":"https://www.academia.edu/Documents/in/Shoulder_joint?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_10975466 coauthored" data-work_id="10975466" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/10975466/Immediate_effects_of_quantified_hamstring_stretching_Hold_relax_proprioceptive_neuromuscular_facilitation_versus_static_stretching">Immediate effects of quantified hamstring stretching: Hold-relax proprioceptive neuromuscular facilitation versus static stretching</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: To compare the immediate effects of a hold-relax proprioceptive neuromuscular facilitation stretching (HR-PNF) versus static stretch (SS) on hamstring flexibility in healthy, asymptomatic subjects. Subjects: Thirty subjects (13... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_10975466" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To compare the immediate effects of a hold-relax proprioceptive neuromuscular facilitation stretching (HR-PNF) versus static stretch (SS) on hamstring flexibility in healthy, asymptomatic subjects. Subjects: Thirty subjects (13 female; mean age 25.7 AE 3.0, range 22e37) without excessive hamstring muscle flexibility were randomly assigned to one of two stretch groups: HR-PNF or SS. Methods: The left leg was treated as a control and did not receive any intervention. The right leg was measured for ROM pre-and post-stretch interventions, with subjects receiving randomly assigned interventions one week apart. Data were analyzed with a 3 (intervention: HR-PNF, SS, control) Â 2 (time: pre and post) factorial ANOVA with repeated measures and appropriate post-hoc analyses.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/10975466" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="effc302e3b3a41d59a9d225be449b794" rel="nofollow" data-download="{"attachment_id":46988997,"asset_id":10975466,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46988997/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26583549" href="https://baylor.academia.edu/EmilioPuentedura">Emilio Puentedura</a><script data-card-contents-for-user="26583549" type="text/json">{"id":26583549,"first_name":"Emilio","last_name":"Puentedura","domain_name":"baylor","page_name":"EmilioPuentedura","display_name":"Emilio Puentedura","profile_url":"https://baylor.academia.edu/EmilioPuentedura?f_ri=71469","photo":"https://0.academia-photos.com/26583549/9037451/10082231/s65_emilio.puentedura.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-10975466">+1</span><div class="hidden js-additional-users-10975466"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://unlv.academia.edu/MerrillLanders">Merrill Landers</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-10975466'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-10975466').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_10975466 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="10975466"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 10975466, container: ".js-paper-rank-work_10975466", }); });</script></li><li class="js-percentile-work_10975466 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10975466; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_10975466"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_10975466 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="10975466"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10975466; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10975466]").text(description); $(".js-view-count-work_10975466").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_10975466").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="10975466"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="32473" rel="nofollow" href="https://www.academia.edu/Documents/in/Physical_Therapy">Physical Therapy</a>, <script data-card-contents-for-ri="32473" type="text/json">{"id":32473,"name":"Physical Therapy","url":"https://www.academia.edu/Documents/in/Physical_Therapy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="54214" rel="nofollow" href="https://www.academia.edu/Documents/in/Proprioception">Proprioception</a>, <script data-card-contents-for-ri="54214" type="text/json">{"id":54214,"name":"Proprioception","url":"https://www.academia.edu/Documents/in/Proprioception?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="129744" rel="nofollow" href="https://www.academia.edu/Documents/in/Confidence_intervals">Confidence intervals</a><script data-card-contents-for-ri="129744" type="text/json">{"id":129744,"name":"Confidence intervals","url":"https://www.academia.edu/Documents/in/Confidence_intervals?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=10975466]'), work: {"id":10975466,"title":"Immediate effects of quantified hamstring stretching: Hold-relax proprioceptive neuromuscular facilitation versus static stretching","created_at":"2015-02-21T08:10:18.113-08:00","url":"https://www.academia.edu/10975466/Immediate_effects_of_quantified_hamstring_stretching_Hold_relax_proprioceptive_neuromuscular_facilitation_versus_static_stretching?f_ri=71469","dom_id":"work_10975466","summary":"Purpose: To compare the immediate effects of a hold-relax proprioceptive neuromuscular facilitation stretching (HR-PNF) versus static stretch (SS) on hamstring flexibility in healthy, asymptomatic subjects. Subjects: Thirty subjects (13 female; mean age 25.7 AE 3.0, range 22e37) without excessive hamstring muscle flexibility were randomly assigned to one of two stretch groups: HR-PNF or SS. Methods: The left leg was treated as a control and did not receive any intervention. The right leg was measured for ROM pre-and post-stretch interventions, with subjects receiving randomly assigned interventions one week apart. Data were analyzed with a 3 (intervention: HR-PNF, SS, control) Â 2 (time: pre and post) factorial ANOVA with repeated measures and appropriate post-hoc analyses.","downloadable_attachments":[{"id":46988997,"asset_id":10975466,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26583549,"first_name":"Emilio","last_name":"Puentedura","domain_name":"baylor","page_name":"EmilioPuentedura","display_name":"Emilio Puentedura","profile_url":"https://baylor.academia.edu/EmilioPuentedura?f_ri=71469","photo":"https://0.academia-photos.com/26583549/9037451/10082231/s65_emilio.puentedura.jpg"},{"id":37739509,"first_name":"Merrill","last_name":"Landers","domain_name":"unlv","page_name":"MerrillLanders","display_name":"Merrill Landers","profile_url":"https://unlv.academia.edu/MerrillLanders?f_ri=71469","photo":"https://0.academia-photos.com/37739509/12872698/14267737/s65_merrill.landers.png"}],"research_interests":[{"id":32473,"name":"Physical Therapy","url":"https://www.academia.edu/Documents/in/Physical_Therapy?f_ri=71469","nofollow":true},{"id":54214,"name":"Proprioception","url":"https://www.academia.edu/Documents/in/Proprioception?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":129744,"name":"Confidence intervals","url":"https://www.academia.edu/Documents/in/Confidence_intervals?f_ri=71469","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=71469"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=71469"},{"id":462777,"name":"Leg","url":"https://www.academia.edu/Documents/in/Leg?f_ri=71469"},{"id":980294,"name":"Range of Motion","url":"https://www.academia.edu/Documents/in/Range_of_Motion?f_ri=71469"},{"id":1145265,"name":"Knee Joint","url":"https://www.academia.edu/Documents/in/Knee_Joint?f_ri=71469"},{"id":1146830,"name":"Cross-Over Studies","url":"https://www.academia.edu/Documents/in/Cross-Over_Studies?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23738665" data-work_id="23738665" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23738665/The_gait_and_balance_of_patients_with_diabetes_can_be_improved_a_randomised_controlled_trial">The gait and balance of patients with diabetes can be improved: a randomised controlled trial</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Aims/hypothesis Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23738665" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Aims/hypothesis Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic patients.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23738665" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b7a12f06ba71a179177084f4fded163d" rel="nofollow" data-download="{"attachment_id":44175419,"asset_id":23738665,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44175419/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="45934325" href="https://independent.academia.edu/StaalB">Bart Staal</a><script data-card-contents-for-user="45934325" type="text/json">{"id":45934325,"first_name":"Bart","last_name":"Staal","domain_name":"independent","page_name":"StaalB","display_name":"Bart Staal","profile_url":"https://independent.academia.edu/StaalB?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_23738665 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23738665"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23738665, container: ".js-paper-rank-work_23738665", }); 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$(".js-view-count[data-work-id=23738665]").text(description); $(".js-view-count-work_23738665").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_23738665").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="23738665"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">26</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="7470" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_of_life">Quality of life</a>, <script data-card-contents-for-ri="7470" type="text/json">{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8207" rel="nofollow" href="https://www.academia.edu/Documents/in/Risk">Risk</a>, <script data-card-contents-for-ri="8207" type="text/json">{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44530" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle_strength">Muscle strength</a>, <script data-card-contents-for-ri="44530" type="text/json">{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="50690" rel="nofollow" href="https://www.academia.edu/Documents/in/Mobility">Mobility</a><script data-card-contents-for-ri="50690" type="text/json">{"id":50690,"name":"Mobility","url":"https://www.academia.edu/Documents/in/Mobility?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23738665]'), work: {"id":23738665,"title":"The gait and balance of patients with diabetes can be improved: a randomised controlled trial","created_at":"2016-03-28T13:18:59.455-07:00","url":"https://www.academia.edu/23738665/The_gait_and_balance_of_patients_with_diabetes_can_be_improved_a_randomised_controlled_trial?f_ri=71469","dom_id":"work_23738665","summary":"Aims/hypothesis Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic patients.","downloadable_attachments":[{"id":44175419,"asset_id":23738665,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":45934325,"first_name":"Bart","last_name":"Staal","domain_name":"independent","page_name":"StaalB","display_name":"Bart Staal","profile_url":"https://independent.academia.edu/StaalB?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":7470,"name":"Quality of life","url":"https://www.academia.edu/Documents/in/Quality_of_life?f_ri=71469","nofollow":true},{"id":8207,"name":"Risk","url":"https://www.academia.edu/Documents/in/Risk?f_ri=71469","nofollow":true},{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=71469","nofollow":true},{"id":50690,"name":"Mobility","url":"https://www.academia.edu/Documents/in/Mobility?f_ri=71469","nofollow":true},{"id":60256,"name":"Gait","url":"https://www.academia.edu/Documents/in/Gait?f_ri=71469"},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":80561,"name":"Variability","url":"https://www.academia.edu/Documents/in/Variability?f_ri=71469"},{"id":84745,"name":"Movement","url":"https://www.academia.edu/Documents/in/Movement?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":144248,"name":"Balance","url":"https://www.academia.edu/Documents/in/Balance?f_ri=71469"},{"id":193798,"name":"Metaanalysis","url":"https://www.academia.edu/Documents/in/Metaanalysis?f_ri=71469"},{"id":194055,"name":"Randomised Controlled Trial","url":"https://www.academia.edu/Documents/in/Randomised_Controlled_Trial?f_ri=71469"},{"id":205097,"name":"Diabetic Foot","url":"https://www.academia.edu/Documents/in/Diabetic_Foot?f_ri=71469"},{"id":218935,"name":"Group Intervention","url":"https://www.academia.edu/Documents/in/Group_Intervention?f_ri=71469"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469"},{"id":247229,"name":"Intervention Studies","url":"https://www.academia.edu/Documents/in/Intervention_Studies?f_ri=71469"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=71469"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=71469"},{"id":534656,"name":"Joint","url":"https://www.academia.edu/Documents/in/Joint?f_ri=71469"},{"id":638048,"name":"Physical Exercise","url":"https://www.academia.edu/Documents/in/Physical_Exercise?f_ri=71469"},{"id":670043,"name":"Joints","url":"https://www.academia.edu/Documents/in/Joints?f_ri=71469"},{"id":749302,"name":"Indexation","url":"https://www.academia.edu/Documents/in/Indexation?f_ri=71469"},{"id":915951,"name":"Type 2 Diabetes Mellitus","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes_Mellitus?f_ri=71469"},{"id":1115730,"name":"Articulation","url":"https://www.academia.edu/Documents/in/Articulation?f_ri=71469"},{"id":1631043,"name":"Control Group","url":"https://www.academia.edu/Documents/in/Control_Group?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_1491368" data-work_id="1491368" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/1491368/Sensing_Muscle_Activities_with_Body_Worn_Sensors">Sensing Muscle Activities with Body-Worn Sensors</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We demonstrate that simple, unobtrusive sensors attached to the lower arm can be used to capture muscle activations during specific hand and arm activities such as grasping. Specifically, we investigate the use of force sensitive... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_1491368" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We demonstrate that simple, unobtrusive sensors attached to the lower arm can be used to capture muscle activations during specific hand and arm activities such as grasping. Specifically, we investigate the use of force sensitive resistors and fabric stretch sensors, that can both be easily integrated into clothing. We use the above sensors to detect the contractions of arm muscles. We present and compare the signals that both sensors produce for a set of typical hand actions. We finally argue that they can provide important information for activity recognition</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/1491368" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b0abffab516775b617548239ef8c4ccd" rel="nofollow" data-download="{"attachment_id":11676764,"asset_id":1491368,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/11676764/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1395578" href="https://independent.academia.edu/EllenMoffat">Ellen Moffat</a><script data-card-contents-for-user="1395578" type="text/json">{"id":1395578,"first_name":"Ellen","last_name":"Moffat","domain_name":"independent","page_name":"EllenMoffat","display_name":"Ellen Moffat","profile_url":"https://independent.academia.edu/EllenMoffat?f_ri=71469","photo":"https://0.academia-photos.com/1395578/505904/636045/s65_ellen.moffat.jpg"}</script></span></span></li><li class="js-paper-rank-work_1491368 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="1491368"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 1491368, container: ".js-paper-rank-work_1491368", }); 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Specifically, we investigate the use of force sensitive resistors and fabric stretch sensors, that can both be easily integrated into clothing. We use the above sensors to detect the contractions of arm muscles. We present and compare the signals that both sensors produce for a set of typical hand actions. We finally argue that they can provide important information for activity recognition","downloadable_attachments":[{"id":11676764,"asset_id":1491368,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1395578,"first_name":"Ellen","last_name":"Moffat","domain_name":"independent","page_name":"EllenMoffat","display_name":"Ellen Moffat","profile_url":"https://independent.academia.edu/EllenMoffat?f_ri=71469","photo":"https://0.academia-photos.com/1395578/505904/636045/s65_ellen.moffat.jpg"}],"research_interests":[{"id":36449,"name":"Activity Recognition","url":"https://www.academia.edu/Documents/in/Activity_Recognition?f_ri=71469","nofollow":true},{"id":36979,"name":"Use of Force","url":"https://www.academia.edu/Documents/in/Use_of_Force?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":115334,"name":"Wearable computers","url":"https://www.academia.edu/Documents/in/Wearable_computers?f_ri=71469","nofollow":true},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":846015,"name":"Electrodes","url":"https://www.academia.edu/Documents/in/Electrodes?f_ri=71469"},{"id":1300379,"name":"Muscle Activity","url":"https://www.academia.edu/Documents/in/Muscle_Activity?f_ri=71469"},{"id":1931321,"name":"Application Software","url":"https://www.academia.edu/Documents/in/Application_Software?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_3558187" data-work_id="3558187" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/3558187/Functional_variation_of_neck_muscles_and_their_relation_to_feeding_style_in_Tyrannosauridae_and_other_large_theropod_dinosaurs">Functional variation of neck muscles and their relation to feeding style in Tyrannosauridae and other large theropod dinosaurs</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Reconstructed neck muscles of large theropod dinosaurs suggest influences on feeding style that paralleled variation in skull mechanics. In all examined theropods, the head dorsiflexor m. transversospinalis capitis probably filled in the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_3558187" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Reconstructed neck muscles of large theropod dinosaurs suggest influences on feeding style that paralleled variation in skull mechanics. In all examined theropods, the head dorsiflexor m. transversospinalis capitis probably filled in the posterior dorsal concavity of the neck, for a more crocodilian-than avian-like profile in this region. The tyrannosaurine tyrannosaurids Daspletosaurus and Tyrannosaurus had relatively larger moment arms for lateroflexion by m. longissimus capitis superficialis and m. complexus than albertosaurine tyrannosaurids, and longer dorsiflexive moment arms for m. complexus. Areas of dorsiflexor origination are significantly larger relative to neck length in adult Tyrannosaurus rex than in other tyrannosaurids, suggesting relatively large muscle cross-sections and forces. Tyrannosaurids were not particularly specialized for neck ventroflexion. In contrast, the hypothesis that Allosaurus co-opted m. longissimus capitis superficialis for ventroflexion is strongly corroborated. Ceratosaurus had robust insertions for the ventroflexors m. longissimus capitis profundus and m. rectus capitis ventralis. Neck muscle morphology is consistent with puncture-and-pull and powerful shake feeding in tyrannosaurids, relatively rapid strikes in Allosaurus and Ceratosaurus, and ventroflexive augmentation of weaker jaw muscle forces in the nontyrannosaurids. Anat Rec, 290:934-957, 2007Rec, 290:934-957, . 2007 Wiley-Liss, Inc.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/3558187" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2493286bf2b91c3d554fb514f001d554" rel="nofollow" data-download="{"attachment_id":31276543,"asset_id":3558187,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/31276543/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="4226763" href="https://michiganstate.academia.edu/TyrannoRex">Tyranno Rex</a><script data-card-contents-for-user="4226763" type="text/json">{"id":4226763,"first_name":"Tyranno","last_name":"Rex","domain_name":"michiganstate","page_name":"TyrannoRex","display_name":"Tyranno Rex","profile_url":"https://michiganstate.academia.edu/TyrannoRex?f_ri=71469","photo":"https://0.academia-photos.com/4226763/1667560/2006437/s65_tyranno.rex.jpg"}</script></span></span></li><li class="js-paper-rank-work_3558187 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="3558187"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 3558187, container: ".js-paper-rank-work_3558187", }); 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In all examined theropods, the head dorsiflexor m. transversospinalis capitis probably filled in the posterior dorsal concavity of the neck, for a more crocodilian-than avian-like profile in this region. The tyrannosaurine tyrannosaurids Daspletosaurus and Tyrannosaurus had relatively larger moment arms for lateroflexion by m. longissimus capitis superficialis and m. complexus than albertosaurine tyrannosaurids, and longer dorsiflexive moment arms for m. complexus. Areas of dorsiflexor origination are significantly larger relative to neck length in adult Tyrannosaurus rex than in other tyrannosaurids, suggesting relatively large muscle cross-sections and forces. Tyrannosaurids were not particularly specialized for neck ventroflexion. In contrast, the hypothesis that Allosaurus co-opted m. longissimus capitis superficialis for ventroflexion is strongly corroborated. Ceratosaurus had robust insertions for the ventroflexors m. longissimus capitis profundus and m. rectus capitis ventralis. Neck muscle morphology is consistent with puncture-and-pull and powerful shake feeding in tyrannosaurids, relatively rapid strikes in Allosaurus and Ceratosaurus, and ventroflexive augmentation of weaker jaw muscle forces in the nontyrannosaurids. Anat Rec, 290:934-957, 2007Rec, 290:934-957, . 2007 Wiley-Liss, Inc.","downloadable_attachments":[{"id":31276543,"asset_id":3558187,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":4226763,"first_name":"Tyranno","last_name":"Rex","domain_name":"michiganstate","page_name":"TyrannoRex","display_name":"Tyranno Rex","profile_url":"https://michiganstate.academia.edu/TyrannoRex?f_ri=71469","photo":"https://0.academia-photos.com/4226763/1667560/2006437/s65_tyranno.rex.jpg"}],"research_interests":[{"id":417,"name":"Paleontology","url":"https://www.academia.edu/Documents/in/Paleontology?f_ri=71469","nofollow":true},{"id":4933,"name":"Spine","url":"https://www.academia.edu/Documents/in/Spine?f_ri=71469","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=71469","nofollow":true},{"id":54433,"name":"Phylogeny","url":"https://www.academia.edu/Documents/in/Phylogeny?f_ri=71469","nofollow":true},{"id":59432,"name":"Dinosaurs","url":"https://www.academia.edu/Documents/in/Dinosaurs?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":202574,"name":"Feeding Behavior","url":"https://www.academia.edu/Documents/in/Feeding_Behavior?f_ri=71469"},{"id":404000,"name":"Cross Section","url":"https://www.academia.edu/Documents/in/Cross_Section?f_ri=71469"},{"id":677681,"name":"Muscle Force","url":"https://www.academia.edu/Documents/in/Muscle_Force?f_ri=71469"},{"id":847989,"name":"Neck Muscles","url":"https://www.academia.edu/Documents/in/Neck_Muscles?f_ri=71469"},{"id":1902100,"name":"Biomechanical Phenomena","url":"https://www.academia.edu/Documents/in/Biomechanical_Phenomena?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_6217781" data-work_id="6217781" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/6217781/Activity_of_upper_body_muscles_during_bowing_and_prostration_tasks_in_healthy_subjects">Activity of upper body muscles during bowing and prostration tasks in healthy subjects</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This paper investigate the activity of the neck extensors (NE), sternocleidomastoideus (SCM), trapezius (TRP), deltoid (DT), biceps brachii (BB), triceps brachii (TB), rectus abdominal (RA), and erector spine (ES) muscles in healthy... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_6217781" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This paper investigate the activity of the neck extensors (NE), sternocleidomastoideus (SCM), trapezius (TRP), deltoid (DT), biceps brachii (BB), triceps brachii (TB), rectus abdominal (RA), and erector spine (ES) muscles in healthy subjects during bowing and prostration using surface electromyography (EMG). A group of student aged between 23 to 28 years voluntarily participated in this study. The subjects were asked to perform two types of flexion positions, namely bowing (90° forward flexion with the hands on the respective knees) and prostration (flexion with the palms of the hands and the forehead flat on the floor). The motion signals of the muscles were recorded. The finding indicated that during the bowing, there was contraction of the NE, DT, TB, and RA muscles while the muscle relaxation was found in the SCM, TRP, BB, and ES. During prostration, there was contraction at the SCM, DT, TB, and RA but muscle relaxation was found at the NE, TRP, BB, and ES. For the muscles that showed electrical activity in both the postures, the Wilcoxon Rank Sum Test showed a statistically no significant difference between bowing and prostration only for DT (p = 0.534) and but statistically significant difference for RA and TB (p<0.05). The muscle relaxation that existed at the ES showed no significant difference between bowing and prostrating (Wilcoxon Rank Sum Test, p = 0.075). This study indicates the effects of bowing and prostration on the biomechanical response of the human muscles. Muscle contraction and relaxation that occur, show an agonist-antagonist response which is good for exercise and strengthening programmers. These two movements are involved in the Muslim's prayer, called the salat. Hence, the current experiment can be taken as a pilot study on the biomechanical response of the human muscles during one's act of performing the salat. © 2011 Springer-Verlag. <br /> <br /><a href="http://link.springer.com/chapter/10.1007/978-3-642-21729-6_34" rel="nofollow">http://link.springer.com/chapter/10.1007/978-3-642-21729-6_34</a></div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/6217781" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ba8cf7cb36e68135659e3891d96597ee" rel="nofollow" data-download="{"attachment_id":33087878,"asset_id":6217781,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/33087878/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="9529839" href="https://malaya.academia.edu/WanAbuBakarWanAbas">Wan Abu Bakar Wan Abas</a><script data-card-contents-for-user="9529839" type="text/json">{"id":9529839,"first_name":"Wan Abu Bakar","last_name":"Wan Abas","domain_name":"malaya","page_name":"WanAbuBakarWanAbas","display_name":"Wan Abu Bakar Wan Abas","profile_url":"https://malaya.academia.edu/WanAbuBakarWanAbas?f_ri=71469","photo":"https://0.academia-photos.com/9529839/3049072/3584786/s65_wan_abu_bakar.wan_abas.jpg"}</script></span></span></li><li class="js-paper-rank-work_6217781 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="6217781"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 6217781, container: ".js-paper-rank-work_6217781", }); 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$(".js-view-count[data-work-id=6217781]").text(description); $(".js-view-count-work_6217781").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_6217781").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="6217781"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">16</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="170918" rel="nofollow" href="https://www.academia.edu/Documents/in/Electromyography">Electromyography</a>, <script data-card-contents-for-ri="170918" type="text/json">{"id":170918,"name":"Electromyography","url":"https://www.academia.edu/Documents/in/Electromyography?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="367313" rel="nofollow" href="https://www.academia.edu/Documents/in/Pilot_Studies">Pilot Studies</a>, <script data-card-contents-for-ri="367313" type="text/json">{"id":367313,"name":"Pilot Studies","url":"https://www.academia.edu/Documents/in/Pilot_Studies?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="466545" rel="nofollow" href="https://www.academia.edu/Documents/in/Bowing">Bowing</a><script data-card-contents-for-ri="466545" type="text/json">{"id":466545,"name":"Bowing","url":"https://www.academia.edu/Documents/in/Bowing?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=6217781]'), work: {"id":6217781,"title":"Activity of upper body muscles during bowing and prostration tasks in healthy subjects","created_at":"2014-02-26T12:35:57.432-08:00","url":"https://www.academia.edu/6217781/Activity_of_upper_body_muscles_during_bowing_and_prostration_tasks_in_healthy_subjects?f_ri=71469","dom_id":"work_6217781","summary":"This paper investigate the activity of the neck extensors (NE), sternocleidomastoideus (SCM), trapezius (TRP), deltoid (DT), biceps brachii (BB), triceps brachii (TB), rectus abdominal (RA), and erector spine (ES) muscles in healthy subjects during bowing and prostration using surface electromyography (EMG). A group of student aged between 23 to 28 years voluntarily participated in this study. The subjects were asked to perform two types of flexion positions, namely bowing (90° forward flexion with the hands on the respective knees) and prostration (flexion with the palms of the hands and the forehead flat on the floor). The motion signals of the muscles were recorded. The finding indicated that during the bowing, there was contraction of the NE, DT, TB, and RA muscles while the muscle relaxation was found in the SCM, TRP, BB, and ES. During prostration, there was contraction at the SCM, DT, TB, and RA but muscle relaxation was found at the NE, TRP, BB, and ES. For the muscles that showed electrical activity in both the postures, the Wilcoxon Rank Sum Test showed a statistically no significant difference between bowing and prostration only for DT (p = 0.534) and but statistically significant difference for RA and TB (p\u003c0.05). The muscle relaxation that existed at the ES showed no significant difference between bowing and prostrating (Wilcoxon Rank Sum Test, p = 0.075). This study indicates the effects of bowing and prostration on the biomechanical response of the human muscles. Muscle contraction and relaxation that occur, show an agonist-antagonist response which is good for exercise and strengthening programmers. These two movements are involved in the Muslim's prayer, called the salat. Hence, the current experiment can be taken as a pilot study on the biomechanical response of the human muscles during one's act of performing the salat. © 2011 Springer-Verlag.\r\n\r\nhttp://link.springer.com/chapter/10.1007/978-3-642-21729-6_34 ","downloadable_attachments":[{"id":33087878,"asset_id":6217781,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":9529839,"first_name":"Wan Abu Bakar","last_name":"Wan Abas","domain_name":"malaya","page_name":"WanAbuBakarWanAbas","display_name":"Wan Abu Bakar Wan Abas","profile_url":"https://malaya.academia.edu/WanAbuBakarWanAbas?f_ri=71469","photo":"https://0.academia-photos.com/9529839/3049072/3584786/s65_wan_abu_bakar.wan_abas.jpg"}],"research_interests":[{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":170918,"name":"Electromyography","url":"https://www.academia.edu/Documents/in/Electromyography?f_ri=71469","nofollow":true},{"id":367313,"name":"Pilot Studies","url":"https://www.academia.edu/Documents/in/Pilot_Studies?f_ri=71469","nofollow":true},{"id":466545,"name":"Bowing","url":"https://www.academia.edu/Documents/in/Bowing?f_ri=71469","nofollow":true},{"id":1142754,"name":"Flexion Relaxation","url":"https://www.academia.edu/Documents/in/Flexion_Relaxation?f_ri=71469"},{"id":1142756,"name":"Prostration","url":"https://www.academia.edu/Documents/in/Prostration?f_ri=71469"},{"id":1142757,"name":"Biceps Brachii","url":"https://www.academia.edu/Documents/in/Biceps_Brachii?f_ri=71469"},{"id":1142758,"name":"Electrical Activities","url":"https://www.academia.edu/Documents/in/Electrical_Activities?f_ri=71469"},{"id":1142759,"name":"Healthy Subjects","url":"https://www.academia.edu/Documents/in/Healthy_Subjects?f_ri=71469"},{"id":1142762,"name":"Muscle Contractions","url":"https://www.academia.edu/Documents/in/Muscle_Contractions?f_ri=71469"},{"id":1142764,"name":"Statistically Significant Difference","url":"https://www.academia.edu/Documents/in/Statistically_Significant_Difference?f_ri=71469"},{"id":1142765,"name":"Surface Electromyography","url":"https://www.academia.edu/Documents/in/Surface_Electromyography?f_ri=71469"},{"id":1142766,"name":"Triceps Brachii","url":"https://www.academia.edu/Documents/in/Triceps_Brachii?f_ri=71469"},{"id":1142767,"name":"Wilcoxon Rank Sum Test","url":"https://www.academia.edu/Documents/in/Wilcoxon_Rank_Sum_Test?f_ri=71469"},{"id":1157260,"name":"Biomechanical Response","url":"https://www.academia.edu/Documents/in/Biomechanical_Response?f_ri=71469"},{"id":1272871,"name":"Muscle Relaxation","url":"https://www.academia.edu/Documents/in/Muscle_Relaxation?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48048036" data-work_id="48048036" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48048036/Postpartum_sexual_function_of_women_and_the_effects_of_early_pelvic_floor_muscle_exercises">Postpartum sexual function of women and the effects of early pelvic floor muscle exercises</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective. To evaluate the effects of early pelvic floor muscle training after vaginal delivery on sexual function. Design. Prospective randomized study. Settings. Urogynecology clinic of a tertiary medical center in Istanbul, Turkey.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48048036" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective. To evaluate the effects of early pelvic floor muscle training after vaginal delivery on sexual function. Design. Prospective randomized study. Settings. Urogynecology clinic of a tertiary medical center in Istanbul, Turkey. Population. Total of 75 primiparous women. Methods. Pelvic floor-muscle strength was assessed during rest and straining in primiparous women in their 4th postpartum month, after which the women were randomized into training (n = 37) and control (n = 38) groups. Patients were re-evaluated in the 7th postpartum month. Main outcome measures. Female sexual function and pelvic muscle strength scores. Results. Desire, pain and total female sexual index scores were significantly higher in the 7th month compared to 4th month in both groups (p < 0.05). However, sexual arousal, lubrication, orgasm, and satisfaction scores were improved in the 7th month in the training group (paired t-test, p < 0.001), but not significantly in the control group (p > 0.05). All domains except satisfaction were significantly higher in the training group compared with the controls. Pelvic floor-muscle strength was found to be increased in the 7th month in the training group (Wilcoxon rank test, Z = 4.123, p < 0.001), whereas there was no significant difference between the 4th and 7th month measurements in the controls (p > 0.05). Conclusion. Pelvic floor-muscle training improves pelvic floor-muscle function, and starting after the puerperal period, exercise appears to have positive effects on female sexual function.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48048036" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1c9c93bbd2d057cb9f3e8eec4205b2f6" rel="nofollow" data-download="{"attachment_id":66862658,"asset_id":48048036,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/66862658/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35203917" href="https://independent.academia.edu/AtesKarateke">Ates Karateke</a><script data-card-contents-for-user="35203917" type="text/json">{"id":35203917,"first_name":"Ates","last_name":"Karateke","domain_name":"independent","page_name":"AtesKarateke","display_name":"Ates Karateke","profile_url":"https://independent.academia.edu/AtesKarateke?f_ri=71469","photo":"https://0.academia-photos.com/35203917/102285617/91450582/s65_ates.karateke.png"}</script></span></span></li><li class="js-paper-rank-work_48048036 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48048036"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48048036, container: ".js-paper-rank-work_48048036", }); 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$(".js-view-count[data-work-id=48048036]").text(description); $(".js-view-count-work_48048036").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_48048036").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="48048036"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">14</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="625" rel="nofollow" href="https://www.academia.edu/Documents/in/Obstetrics">Obstetrics</a>, <script data-card-contents-for-ri="625" type="text/json">{"id":625,"name":"Obstetrics","url":"https://www.academia.edu/Documents/in/Obstetrics?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4714" rel="nofollow" href="https://www.academia.edu/Documents/in/Sexuality">Sexuality</a>, <script data-card-contents-for-ri="4714" type="text/json">{"id":4714,"name":"Sexuality","url":"https://www.academia.edu/Documents/in/Sexuality?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="25443" rel="nofollow" href="https://www.academia.edu/Documents/in/Exercise_therapy">Exercise therapy</a>, <script data-card-contents-for-ri="25443" type="text/json">{"id":25443,"name":"Exercise therapy","url":"https://www.academia.edu/Documents/in/Exercise_therapy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="62112" rel="nofollow" href="https://www.academia.edu/Documents/in/Prospective_studies">Prospective studies</a><script data-card-contents-for-ri="62112" type="text/json">{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=48048036]'), work: {"id":48048036,"title":"Postpartum sexual function of women and the effects of early pelvic floor muscle exercises","created_at":"2021-05-03T23:52:32.279-07:00","url":"https://www.academia.edu/48048036/Postpartum_sexual_function_of_women_and_the_effects_of_early_pelvic_floor_muscle_exercises?f_ri=71469","dom_id":"work_48048036","summary":"Objective. To evaluate the effects of early pelvic floor muscle training after vaginal delivery on sexual function. Design. Prospective randomized study. Settings. Urogynecology clinic of a tertiary medical center in Istanbul, Turkey. Population. Total of 75 primiparous women. Methods. Pelvic floor-muscle strength was assessed during rest and straining in primiparous women in their 4th postpartum month, after which the women were randomized into training (n = 37) and control (n = 38) groups. Patients were re-evaluated in the 7th postpartum month. Main outcome measures. Female sexual function and pelvic muscle strength scores. Results. Desire, pain and total female sexual index scores were significantly higher in the 7th month compared to 4th month in both groups (p \u003c 0.05). However, sexual arousal, lubrication, orgasm, and satisfaction scores were improved in the 7th month in the training group (paired t-test, p \u003c 0.001), but not significantly in the control group (p \u003e 0.05). All domains except satisfaction were significantly higher in the training group compared with the controls. Pelvic floor-muscle strength was found to be increased in the 7th month in the training group (Wilcoxon rank test, Z = 4.123, p \u003c 0.001), whereas there was no significant difference between the 4th and 7th month measurements in the controls (p \u003e 0.05). Conclusion. Pelvic floor-muscle training improves pelvic floor-muscle function, and starting after the puerperal period, exercise appears to have positive effects on female sexual function.","downloadable_attachments":[{"id":66862658,"asset_id":48048036,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35203917,"first_name":"Ates","last_name":"Karateke","domain_name":"independent","page_name":"AtesKarateke","display_name":"Ates Karateke","profile_url":"https://independent.academia.edu/AtesKarateke?f_ri=71469","photo":"https://0.academia-photos.com/35203917/102285617/91450582/s65_ates.karateke.png"}],"research_interests":[{"id":625,"name":"Obstetrics","url":"https://www.academia.edu/Documents/in/Obstetrics?f_ri=71469","nofollow":true},{"id":4714,"name":"Sexuality","url":"https://www.academia.edu/Documents/in/Sexuality?f_ri=71469","nofollow":true},{"id":25443,"name":"Exercise therapy","url":"https://www.academia.edu/Documents/in/Exercise_therapy?f_ri=71469","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":339107,"name":"Gynecology","url":"https://www.academia.edu/Documents/in/Gynecology?f_ri=71469"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=71469"},{"id":638048,"name":"Physical Exercise","url":"https://www.academia.edu/Documents/in/Physical_Exercise?f_ri=71469"},{"id":723979,"name":"Sexual Function","url":"https://www.academia.edu/Documents/in/Sexual_Function?f_ri=71469"},{"id":3067129,"name":"postpartum period","url":"https://www.academia.edu/Documents/in/postpartum_period?f_ri=71469"},{"id":3103429,"name":"Pelvic Floor","url":"https://www.academia.edu/Documents/in/Pelvic_Floor?f_ri=71469"},{"id":3789883,"name":"Paediatrics and reproductive medicine","url":"https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_50101146" data-work_id="50101146" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/50101146/Physiopathologie_de_la_d%C3%A9nutrition_en_r%C3%A9animation">Physiopathologie de la dénutrition en réanimation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">La prévalence de la dénutrition est proche de 50 % à l'admission à l'hôpital et particulièrement à l'entrée en réanimation. L'état nutritionnel s'aggrave le plus souvent pendant le séjour du fait des différentes agressions subies en... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_50101146" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">La prévalence de la dénutrition est proche de 50 % à l'admission à l'hôpital et particulièrement à l'entrée en réanimation. L'état nutritionnel s'aggrave le plus souvent pendant le séjour du fait des différentes agressions subies en réanimation et de l'insuffisance d'apport. L'agression induit une augmentation des dépenses énergétiques et un hypercatabolisme protéique. Cette adaptation métabolique de l'organisme entraîne des modifications notables de la composition corporelle et plus particulièrement une diminution de la masse maigre. Celle-ci se fait principalement au dépend de la masse musculaire qui développe des atteintes structurelles à l'origine de conséquences fonctionnelles compromettant la réhabilitation. L'année qui suit le séjour en réanimation est souvent marquée par une persistance de la dénutrition, voire d'une aggravation de l'état nutritionnel et d'une mortalité d'environ 20 %. Ces données soulignent l'importance de la compréhension de la physiopathologie de la dénutrition en réanimation, abordée dans cet article, et de sa prise en charge.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/50101146" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a7198cd35fbd0c824a556a1d5f1ab6df" rel="nofollow" data-download="{"attachment_id":68212835,"asset_id":50101146,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/68212835/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="197101037" href="https://independent.academia.edu/NoelCano7">Noel Cano</a><script data-card-contents-for-user="197101037" type="text/json">{"id":197101037,"first_name":"Noel","last_name":"Cano","domain_name":"independent","page_name":"NoelCano7","display_name":"Noel Cano","profile_url":"https://independent.academia.edu/NoelCano7?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_50101146 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="50101146"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 50101146, container: ".js-paper-rank-work_50101146", }); 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$(".js-view-count[data-work-id=50101146]").text(description); $(".js-view-count-work_50101146").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_50101146").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="50101146"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1907" rel="nofollow" href="https://www.academia.edu/Documents/in/Nutrition">Nutrition</a>, <script data-card-contents-for-ri="1907" type="text/json">{"id":1907,"name":"Nutrition","url":"https://www.academia.edu/Documents/in/Nutrition?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="8141" rel="nofollow" href="https://www.academia.edu/Documents/in/IT_Management">IT Management</a>, <script data-card-contents-for-ri="8141" type="text/json">{"id":8141,"name":"IT Management","url":"https://www.academia.edu/Documents/in/IT_Management?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9729" rel="nofollow" href="https://www.academia.edu/Documents/in/Stress">Stress</a>, <script data-card-contents-for-ri="9729" type="text/json">{"id":9729,"name":"Stress","url":"https://www.academia.edu/Documents/in/Stress?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="39001" rel="nofollow" href="https://www.academia.edu/Documents/in/Pathophysiology">Pathophysiology</a><script data-card-contents-for-ri="39001" type="text/json">{"id":39001,"name":"Pathophysiology","url":"https://www.academia.edu/Documents/in/Pathophysiology?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=50101146]'), work: {"id":50101146,"title":"Physiopathologie de la dénutrition en réanimation","created_at":"2021-07-20T08:08:34.771-07:00","url":"https://www.academia.edu/50101146/Physiopathologie_de_la_d%C3%A9nutrition_en_r%C3%A9animation?f_ri=71469","dom_id":"work_50101146","summary":"La prévalence de la dénutrition est proche de 50 % à l'admission à l'hôpital et particulièrement à l'entrée en réanimation. L'état nutritionnel s'aggrave le plus souvent pendant le séjour du fait des différentes agressions subies en réanimation et de l'insuffisance d'apport. L'agression induit une augmentation des dépenses énergétiques et un hypercatabolisme protéique. Cette adaptation métabolique de l'organisme entraîne des modifications notables de la composition corporelle et plus particulièrement une diminution de la masse maigre. Celle-ci se fait principalement au dépend de la masse musculaire qui développe des atteintes structurelles à l'origine de conséquences fonctionnelles compromettant la réhabilitation. L'année qui suit le séjour en réanimation est souvent marquée par une persistance de la dénutrition, voire d'une aggravation de l'état nutritionnel et d'une mortalité d'environ 20 %. Ces données soulignent l'importance de la compréhension de la physiopathologie de la dénutrition en réanimation, abordée dans cet article, et de sa prise en charge.","downloadable_attachments":[{"id":68212835,"asset_id":50101146,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":197101037,"first_name":"Noel","last_name":"Cano","domain_name":"independent","page_name":"NoelCano7","display_name":"Noel Cano","profile_url":"https://independent.academia.edu/NoelCano7?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1907,"name":"Nutrition","url":"https://www.academia.edu/Documents/in/Nutrition?f_ri=71469","nofollow":true},{"id":8141,"name":"IT Management","url":"https://www.academia.edu/Documents/in/IT_Management?f_ri=71469","nofollow":true},{"id":9729,"name":"Stress","url":"https://www.academia.edu/Documents/in/Stress?f_ri=71469","nofollow":true},{"id":39001,"name":"Pathophysiology","url":"https://www.academia.edu/Documents/in/Pathophysiology?f_ri=71469","nofollow":true},{"id":49646,"name":"Protein Structure and Function","url":"https://www.academia.edu/Documents/in/Protein_Structure_and_Function?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":100336,"name":"Body Composition","url":"https://www.academia.edu/Documents/in/Body_Composition?f_ri=71469"},{"id":184304,"name":"Energy Expenditure","url":"https://www.academia.edu/Documents/in/Energy_Expenditure?f_ri=71469"},{"id":192551,"name":"Nutritional Status","url":"https://www.academia.edu/Documents/in/Nutritional_Status?f_ri=71469"},{"id":263029,"name":"Intensive Care Unit","url":"https://www.academia.edu/Documents/in/Intensive_Care_Unit?f_ri=71469"},{"id":922296,"name":"Review of Literature Protein Energy Malnutrition","url":"https://www.academia.edu/Documents/in/Review_of_Literature_Protein_Energy_Malnutrition?f_ri=71469"},{"id":1680434,"name":"Mortality rate","url":"https://www.academia.edu/Documents/in/Mortality_rate?f_ri=71469"},{"id":2172416,"name":"Muscle mass","url":"https://www.academia.edu/Documents/in/Muscle_mass?f_ri=71469"},{"id":2183171,"name":"Nutrient Intake","url":"https://www.academia.edu/Documents/in/Nutrient_Intake?f_ri=71469"},{"id":2538087,"name":"Lean Body Mass","url":"https://www.academia.edu/Documents/in/Lean_Body_Mass?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23624644" data-work_id="23624644" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23624644/Nerve_conduction_velocity_decrease_and_synaptic_transmission_alterations_in_caffeine_treated_rats">Nerve conduction velocity decrease and synaptic transmission alterations in caffeine-treated rats</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23624644" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="67f05d62279045c6653bda1646879f03" rel="nofollow" data-download="{"attachment_id":44038365,"asset_id":23624644,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44038365/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="45678185" href="https://independent.academia.edu/JRoma1">J. Roma</a><script data-card-contents-for-user="45678185" type="text/json">{"id":45678185,"first_name":"J.","last_name":"Roma","domain_name":"independent","page_name":"JRoma1","display_name":"J. Roma","profile_url":"https://independent.academia.edu/JRoma1?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_23624644 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23624644"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23624644, container: ".js-paper-rank-work_23624644", }); });</script></li><li class="js-percentile-work_23624644 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 23624644; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_23624644"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_23624644 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="23624644"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 23624644; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=23624644]").text(description); $(".js-view-count-work_23624644").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_23624644").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="23624644"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="237" rel="nofollow" href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a>, <script data-card-contents-for-ri="237" type="text/json">{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2007" rel="nofollow" href="https://www.academia.edu/Documents/in/Electrophysiology">Electrophysiology</a>, <script data-card-contents-for-ri="2007" type="text/json">{"id":2007,"name":"Electrophysiology","url":"https://www.academia.edu/Documents/in/Electrophysiology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="51688" rel="nofollow" href="https://www.academia.edu/Documents/in/Neurotoxicology">Neurotoxicology</a>, <script data-card-contents-for-ri="51688" type="text/json">{"id":51688,"name":"Neurotoxicology","url":"https://www.academia.edu/Documents/in/Neurotoxicology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="67129" rel="nofollow" href="https://www.academia.edu/Documents/in/Caffeine">Caffeine</a><script data-card-contents-for-ri="67129" type="text/json">{"id":67129,"name":"Caffeine","url":"https://www.academia.edu/Documents/in/Caffeine?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23624644]'), work: {"id":23624644,"title":"Nerve conduction velocity decrease and synaptic transmission alterations in caffeine-treated rats","created_at":"2016-03-23T11:22:05.006-07:00","url":"https://www.academia.edu/23624644/Nerve_conduction_velocity_decrease_and_synaptic_transmission_alterations_in_caffeine_treated_rats?f_ri=71469","dom_id":"work_23624644","summary":null,"downloadable_attachments":[{"id":44038365,"asset_id":23624644,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":45678185,"first_name":"J.","last_name":"Roma","domain_name":"independent","page_name":"JRoma1","display_name":"J. Roma","profile_url":"https://independent.academia.edu/JRoma1?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=71469","nofollow":true},{"id":2007,"name":"Electrophysiology","url":"https://www.academia.edu/Documents/in/Electrophysiology?f_ri=71469","nofollow":true},{"id":51688,"name":"Neurotoxicology","url":"https://www.academia.edu/Documents/in/Neurotoxicology?f_ri=71469","nofollow":true},{"id":67129,"name":"Caffeine","url":"https://www.academia.edu/Documents/in/Caffeine?f_ri=71469","nofollow":true},{"id":67405,"name":"Toxicity","url":"https://www.academia.edu/Documents/in/Toxicity?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":176503,"name":"Synaptic Transmission","url":"https://www.academia.edu/Documents/in/Synaptic_Transmission?f_ri=71469"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=71469"},{"id":417494,"name":"Rat","url":"https://www.academia.edu/Documents/in/Rat?f_ri=71469"},{"id":418263,"name":"SYNAPSES","url":"https://www.academia.edu/Documents/in/SYNAPSES?f_ri=71469"},{"id":564878,"name":"Body Weight","url":"https://www.academia.edu/Documents/in/Body_Weight?f_ri=71469"},{"id":564879,"name":"Wistar Rats","url":"https://www.academia.edu/Documents/in/Wistar_Rats?f_ri=71469"},{"id":585241,"name":"Conduction Velocity","url":"https://www.academia.edu/Documents/in/Conduction_Velocity?f_ri=71469"},{"id":666669,"name":"Action potential","url":"https://www.academia.edu/Documents/in/Action_potential?f_ri=71469"},{"id":955727,"name":"Action Potentials","url":"https://www.academia.edu/Documents/in/Action_Potentials?f_ri=71469"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=71469"},{"id":1292776,"name":"Nerve Conduction Velocity","url":"https://www.academia.edu/Documents/in/Nerve_Conduction_Velocity?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27013787 coauthored" data-work_id="27013787" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27013787/Myofibrillar_disruption_following_acute_concentric_and_eccentric_resistance_exercise_in_strength_trained_men">Myofibrillar disruption following acute concentric and eccentric resistance exercise in strength-trained men</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We have previously quantified the extent of myofibrillar disruption which occurs following an acute bout of resistance exercise in untrained men, however the response of well-trained subjects is not known. We therefore recruited six... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27013787" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We have previously quantified the extent of myofibrillar disruption which occurs following an acute bout of resistance exercise in untrained men, however the response of well-trained subjects is not known. We therefore recruited six strength-trained men, who ceased training for 5 days and then performed 8 sets of 8 uni-lateral repetitions, using a load equivalent to 80% of their concentric (Con) 1-repetition maximum. One arm performed only Con actions by lifting the weight and the other arm performed only eccentric actions (Ecc) by lowering it. Needle biopsy samples were obtained from biceps brachii of each arm~21 h following exercise, and at baseline (i.e., after 5 days without training), and subsequently analyzed using electron microscopy to quantify myofibrillar disruption. A greater (P ≤ 0.05) proportion of disrupted fibres was found in the Ecc arm (45 ± 11%) compared with baseline values (4 ± 2%), whereas fibre disruption in the Con arm (27 ± 4%) was not different (P > 0.05) from baseline values. The proportion of disrupted fibres and the magnitude of disruption (quantified by sarcomere counting) was considerably less severe than previously observed in untrained subjects after an identical exercise bout. Mixed muscle protein synthesis, assessed from~21-29 h post-exercise, was not different between the Con-and Ecc-exercised arms. We conclude that the Ecc phase of resistance exercise is most disruptive to skeletal muscle and that training attenuates the severity of this effect. Moreover, it appears that fibre disruption induced by habitual weightlifting exercise is essentially repaired after 5 days of inactivity in trained men.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27013787" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a34a5a4d98ee7d36cb631f276bb52725" rel="nofollow" data-download="{"attachment_id":47273107,"asset_id":27013787,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47273107/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51042771" href="https://independent.academia.edu/BrianRoy7">Brian Roy</a><script data-card-contents-for-user="51042771" type="text/json">{"id":51042771,"first_name":"Brian","last_name":"Roy","domain_name":"independent","page_name":"BrianRoy7","display_name":"Brian Roy","profile_url":"https://independent.academia.edu/BrianRoy7?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-27013787">+1</span><div class="hidden js-additional-users-27013787"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://wustl.academia.edu/KevinYarasheskiPhD">Kevin E Yarasheski, PhD</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-27013787'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-27013787').html(); 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We therefore recruited six strength-trained men, who ceased training for 5 days and then performed 8 sets of 8 uni-lateral repetitions, using a load equivalent to 80% of their concentric (Con) 1-repetition maximum. One arm performed only Con actions by lifting the weight and the other arm performed only eccentric actions (Ecc) by lowering it. Needle biopsy samples were obtained from biceps brachii of each arm~21 h following exercise, and at baseline (i.e., after 5 days without training), and subsequently analyzed using electron microscopy to quantify myofibrillar disruption. A greater (P ≤ 0.05) proportion of disrupted fibres was found in the Ecc arm (45 ± 11%) compared with baseline values (4 ± 2%), whereas fibre disruption in the Con arm (27 ± 4%) was not different (P \u003e 0.05) from baseline values. The proportion of disrupted fibres and the magnitude of disruption (quantified by sarcomere counting) was considerably less severe than previously observed in untrained subjects after an identical exercise bout. Mixed muscle protein synthesis, assessed from~21-29 h post-exercise, was not different between the Con-and Ecc-exercised arms. We conclude that the Ecc phase of resistance exercise is most disruptive to skeletal muscle and that training attenuates the severity of this effect. Moreover, it appears that fibre disruption induced by habitual weightlifting exercise is essentially repaired after 5 days of inactivity in trained men.","downloadable_attachments":[{"id":47273107,"asset_id":27013787,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51042771,"first_name":"Brian","last_name":"Roy","domain_name":"independent","page_name":"BrianRoy7","display_name":"Brian Roy","profile_url":"https://independent.academia.edu/BrianRoy7?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":32439,"first_name":"Kevin","last_name":"Yarasheski, PhD","domain_name":"wustl","page_name":"KevinYarasheskiPhD","display_name":"Kevin E Yarasheski, PhD","profile_url":"https://wustl.academia.edu/KevinYarasheskiPhD?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":167,"name":"Physiology","url":"https://www.academia.edu/Documents/in/Physiology?f_ri=71469","nofollow":true},{"id":38139,"name":"Protein synthesis","url":"https://www.academia.edu/Documents/in/Protein_synthesis?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":81173,"name":"Strength Training","url":"https://www.academia.edu/Documents/in/Strength_Training?f_ri=71469","nofollow":true},{"id":96098,"name":"Resistance","url":"https://www.academia.edu/Documents/in/Resistance?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":186234,"name":"Medical Physiology","url":"https://www.academia.edu/Documents/in/Medical_Physiology?f_ri=71469"},{"id":638048,"name":"Physical Exercise","url":"https://www.academia.edu/Documents/in/Physical_Exercise?f_ri=71469"},{"id":771538,"name":"Resistance Exercise","url":"https://www.academia.edu/Documents/in/Resistance_Exercise?f_ri=71469"},{"id":1014845,"name":"Physical Training","url":"https://www.academia.edu/Documents/in/Physical_Training?f_ri=71469"},{"id":1154524,"name":"Eccentric","url":"https://www.academia.edu/Documents/in/Eccentric?f_ri=71469"},{"id":1209864,"name":"Myofibrils","url":"https://www.academia.edu/Documents/in/Myofibrils?f_ri=71469"},{"id":1558340,"name":"Physical Education and training","url":"https://www.academia.edu/Documents/in/Physical_Education_and_training?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19394810" data-work_id="19394810" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19394810/Inflammatory_response_in_facioscapulohumeral_muscular_dystrophy_FSHD_Immunocytochemical_and_genetic_analyses">Inflammatory response in facioscapulohumeral muscular dystrophy (FSHD): Immunocytochemical and genetic analyses</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To investigate the nature of the inflammatory response in facioscapulohumeral muscular dystrophy (FSHD), we analyzed mononuclear cells in muscle sections obtained from 18 FSHD patients and 8 controls. Monoclonal antibodies reactive for T... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_19394810" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To investigate the nature of the inflammatory response in facioscapulohumeral muscular dystrophy (FSHD), we analyzed mononuclear cells in muscle sections obtained from 18 FSHD patients and 8 controls. Monoclonal antibodies reactive for T cells, T cell subsets, B cells, and NK cells were used for cell typing. Macrophages were identified by acid phosphatase reaction. The localization of perforin, granzyme A, MHC-I and -11, dystrophin, and a-actinin antigens was also examined. We found that all FSHD patients, both familiar and sporadic cases, had greater amounts of mononuclear cellular infiltrates in muscle than controls, in whose specimens only few extra vascular mononuclear cells were counted. Seventy-two percent (13 of 18) of the patients had more than 50 inflammatory mononuclear cells per 1000 muscle fibers, and 33% (6 of 18) patients had numerous inflammatory cells exceeding 600 per 1000 muscle fibers (1835 & 482 SE). Nonnecrotic fibers invaded by mononuclear cells with either T8+, perforin+, or granzyme A + were not observed in FSHD, while a few degenerating fibers were superficially invaded by T cells and macrophages. Occasional T cells were observed moving through the blood vessel wall. The increased number of necrotic fibers was paralleled by an increased number of inflammatory cells (r = 0.783, P = 0.0001). Genetic analysis, using the probes p13E-11, pFR-1, D4S139, and D4S163, was done in 6 patients (3 familiar, 3 sporadic) who had numerous inflammatory infiltrates. These 6 patients had small (<28 kb) EcoRl fragments associated with the disease, and the disease was linked to 4q35. These results suggest that, in chromosome b l i n k e d FSHD: (1) inflammatory changes in muscle are a common histological feature; (2) mononuclear cellular infiltrates may enhance muscle fiber damage; but (3) T-cell-mediated cytotoxicity directed against muscle fibers is unlikely. We speculate that the immune effector mechanism in FSHD is different from that in previously reported inflammatory myopathies and Duchenne muscular dystrophy.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19394810" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b250580f2eba3a72d8fedd8b011117fb" rel="nofollow" data-download="{"attachment_id":40596231,"asset_id":19394810,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40596231/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39665451" href="https://independent.academia.edu/SOrimo">Satoshi Orimo</a><script data-card-contents-for-user="39665451" type="text/json">{"id":39665451,"first_name":"Satoshi","last_name":"Orimo","domain_name":"independent","page_name":"SOrimo","display_name":"Satoshi Orimo","profile_url":"https://independent.academia.edu/SOrimo?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_19394810 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19394810"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19394810, container: ".js-paper-rank-work_19394810", }); 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Monoclonal antibodies reactive for T cells, T cell subsets, B cells, and NK cells were used for cell typing. Macrophages were identified by acid phosphatase reaction. The localization of perforin, granzyme A, MHC-I and -11, dystrophin, and a-actinin antigens was also examined. We found that all FSHD patients, both familiar and sporadic cases, had greater amounts of mononuclear cellular infiltrates in muscle than controls, in whose specimens only few extra vascular mononuclear cells were counted. Seventy-two percent (13 of 18) of the patients had more than 50 inflammatory mononuclear cells per 1000 muscle fibers, and 33% (6 of 18) patients had numerous inflammatory cells exceeding 600 per 1000 muscle fibers (1835 \u0026 482 SE). Nonnecrotic fibers invaded by mononuclear cells with either T8+, perforin+, or granzyme A + were not observed in FSHD, while a few degenerating fibers were superficially invaded by T cells and macrophages. Occasional T cells were observed moving through the blood vessel wall. The increased number of necrotic fibers was paralleled by an increased number of inflammatory cells (r = 0.783, P = 0.0001). Genetic analysis, using the probes p13E-11, pFR-1, D4S139, and D4S163, was done in 6 patients (3 familiar, 3 sporadic) who had numerous inflammatory infiltrates. These 6 patients had small (\u003c28 kb) EcoRl fragments associated with the disease, and the disease was linked to 4q35. These results suggest that, in chromosome b l i n k e d FSHD: (1) inflammatory changes in muscle are a common histological feature; (2) mononuclear cellular infiltrates may enhance muscle fiber damage; but (3) T-cell-mediated cytotoxicity directed against muscle fibers is unlikely. We speculate that the immune effector mechanism in FSHD is different from that in previously reported inflammatory myopathies and Duchenne muscular dystrophy.","downloadable_attachments":[{"id":40596231,"asset_id":19394810,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39665451,"first_name":"Satoshi","last_name":"Orimo","domain_name":"independent","page_name":"SOrimo","display_name":"Satoshi Orimo","profile_url":"https://independent.academia.edu/SOrimo?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=71469","nofollow":true},{"id":11636,"name":"Face","url":"https://www.academia.edu/Documents/in/Face?f_ri=71469","nofollow":true},{"id":12071,"name":"Immunohistochemistry","url":"https://www.academia.edu/Documents/in/Immunohistochemistry?f_ri=71469","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=71469"},{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA?f_ri=71469"},{"id":48181,"name":"Inflammatory Immune Response","url":"https://www.academia.edu/Documents/in/Inflammatory_Immune_Response?f_ri=71469"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":89118,"name":"Muscular Dystrophy","url":"https://www.academia.edu/Documents/in/Muscular_Dystrophy?f_ri=71469"},{"id":98995,"name":"Muscular Dystrophies","url":"https://www.academia.edu/Documents/in/Muscular_Dystrophies?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":360548,"name":"Humerus","url":"https://www.academia.edu/Documents/in/Humerus?f_ri=71469"},{"id":407851,"name":"Myositis","url":"https://www.academia.edu/Documents/in/Myositis?f_ri=71469"},{"id":2044714,"name":"Scapula","url":"https://www.academia.edu/Documents/in/Scapula?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13595161 coauthored" data-work_id="13595161" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13595161/Manual_stimulation_of_the_orbicularis_oculi_muscle_improves_eyelid_closure_after_facial_nerve_injury_in_adult_rats">Manual stimulation of the orbicularis oculi muscle improves eyelid closure after facial nerve injury in adult rats</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We have shown that manual stimulation of rat whisker-pad muscles following facial-facial-anastomosis (FFA) restores normal whisking by lowering the proportion of polyinnervated motor endplates. Here we examined whether manual stimulation... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13595161" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We have shown that manual stimulation of rat whisker-pad muscles following facial-facial-anastomosis (FFA) restores normal whisking by lowering the proportion of polyinnervated motor endplates. Here we examined whether manual stimulation of the orbicularis oculi muscle (OOM) after FFA would also improve outcome. Blink responses to standardized air puffs were analyzed using video-based motion analysis. Two months after FFA, blink capacity was impaired, as indicated by a largely increased minimum distance between the eyelids after air-puff stimulation compared with intact rats (2.7 Ϯ 0.4 vs. 0.2 Ϯ 0.01 mm). Manual stimulation reduced this deficit by a factor of two (1.3 Ϯ 0.5 mm). The functional improvement after manual stimulation was associated with a 2-fold decrease in the proportion of polyinnervated OOM endplates (21 Ϯ 10% vs. 42 Ϯ 10% without manual stimulation, 0% in intact rats). We conclude that manual stimulation is a noninvasive and simple procedure with immediate potential for clinical rehabilitation of eyelid closure following facial nerve injury.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13595161" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="bef3d5ad2efeadd6c8456f6db88410ca" rel="nofollow" data-download="{"attachment_id":45175536,"asset_id":13595161,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45175536/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32771547" href="https://independent.academia.edu/DoychinAngelov">Doychin Angelov</a><script data-card-contents-for-user="32771547" type="text/json">{"id":32771547,"first_name":"Doychin","last_name":"Angelov","domain_name":"independent","page_name":"DoychinAngelov","display_name":"Doychin Angelov","profile_url":"https://independent.academia.edu/DoychinAngelov?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13595161">+2</span><div class="hidden js-additional-users-13595161"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://uni-koln.academia.edu/ESkouras">E. Skouras</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/MariaGrosheva">Maria Grosheva</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-13595161'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-13595161').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_13595161 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13595161"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13595161, container: ".js-paper-rank-work_13595161", }); });</script></li><li class="js-percentile-work_13595161 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 13595161; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_13595161"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_13595161 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="13595161"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 13595161; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=13595161]").text(description); $(".js-view-count-work_13595161").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13595161").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13595161"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="19537" rel="nofollow" href="https://www.academia.edu/Documents/in/Biometry">Biometry</a>, <script data-card-contents-for-ri="19537" type="text/json">{"id":19537,"name":"Biometry","url":"https://www.academia.edu/Documents/in/Biometry?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="243672" rel="nofollow" href="https://www.academia.edu/Documents/in/Nerve_Regeneration">Nerve Regeneration</a>, <script data-card-contents-for-ri="243672" type="text/json">{"id":243672,"name":"Nerve Regeneration","url":"https://www.academia.edu/Documents/in/Nerve_Regeneration?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="251271" rel="nofollow" href="https://www.academia.edu/Documents/in/Facial_Nerve">Facial Nerve</a><script data-card-contents-for-ri="251271" type="text/json">{"id":251271,"name":"Facial Nerve","url":"https://www.academia.edu/Documents/in/Facial_Nerve?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13595161]'), work: {"id":13595161,"title":"Manual stimulation of the orbicularis oculi muscle improves eyelid closure after facial nerve injury in adult rats","created_at":"2015-07-03T12:45:46.888-07:00","url":"https://www.academia.edu/13595161/Manual_stimulation_of_the_orbicularis_oculi_muscle_improves_eyelid_closure_after_facial_nerve_injury_in_adult_rats?f_ri=71469","dom_id":"work_13595161","summary":"We have shown that manual stimulation of rat whisker-pad muscles following facial-facial-anastomosis (FFA) restores normal whisking by lowering the proportion of polyinnervated motor endplates. Here we examined whether manual stimulation of the orbicularis oculi muscle (OOM) after FFA would also improve outcome. Blink responses to standardized air puffs were analyzed using video-based motion analysis. Two months after FFA, blink capacity was impaired, as indicated by a largely increased minimum distance between the eyelids after air-puff stimulation compared with intact rats (2.7 Ϯ 0.4 vs. 0.2 Ϯ 0.01 mm). Manual stimulation reduced this deficit by a factor of two (1.3 Ϯ 0.5 mm). The functional improvement after manual stimulation was associated with a 2-fold decrease in the proportion of polyinnervated OOM endplates (21 Ϯ 10% vs. 42 Ϯ 10% without manual stimulation, 0% in intact rats). We conclude that manual stimulation is a noninvasive and simple procedure with immediate potential for clinical rehabilitation of eyelid closure following facial nerve injury.","downloadable_attachments":[{"id":45175536,"asset_id":13595161,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32771547,"first_name":"Doychin","last_name":"Angelov","domain_name":"independent","page_name":"DoychinAngelov","display_name":"Doychin Angelov","profile_url":"https://independent.academia.edu/DoychinAngelov?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":32938069,"first_name":"E.","last_name":"Skouras","domain_name":"uni-koln","page_name":"ESkouras","display_name":"E. Skouras","profile_url":"https://uni-koln.academia.edu/ESkouras?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":32813688,"first_name":"Maria","last_name":"Grosheva","domain_name":"independent","page_name":"MariaGrosheva","display_name":"Maria Grosheva","profile_url":"https://independent.academia.edu/MariaGrosheva?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":19537,"name":"Biometry","url":"https://www.academia.edu/Documents/in/Biometry?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":243672,"name":"Nerve Regeneration","url":"https://www.academia.edu/Documents/in/Nerve_Regeneration?f_ri=71469","nofollow":true},{"id":251271,"name":"Facial Nerve","url":"https://www.academia.edu/Documents/in/Facial_Nerve?f_ri=71469","nofollow":true},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=71469"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=71469"},{"id":564879,"name":"Wistar Rats","url":"https://www.academia.edu/Documents/in/Wistar_Rats?f_ri=71469"},{"id":2234200,"name":"Functional Laterality","url":"https://www.academia.edu/Documents/in/Functional_Laterality?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_52536711" data-work_id="52536711" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/52536711/Biocompatibility_of_a_physiological_pressure_sensor">Biocompatibility of a physiological pressure sensor</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A newly developed fiber optic micropressure sensor was evaluated for biocompatibility using the International Organization for Standardization (ISO) test standard 10993-6. The test material and an inert control (fused silica glass) were... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_52536711" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A newly developed fiber optic micropressure sensor was evaluated for biocompatibility using the International Organization for Standardization (ISO) test standard 10993-6. The test material and an inert control (fused silica glass) were tested in New Zealand white rabbits. Four test specimens were implanted in the paravertebral muscles on one side of the spine about 2 Á/5 cm from the midline and parallel to the spinal column. Similarly, four control specimens were implanted on the opposite side. The implantation periods were 1, 4, and 12 weeks to ensure a steady state biological tissue response. Four animals were tested at each time period. Macroscopic and microscopic observations were performed to compare the biological reactions between the test and control materials. There was an inflammatory reaction at 1 week which subsided at 4 weeks. There was fibrous tissue growth near the implant that also decreased over time. Most importantly, there was no significant difference in the biological response between the test and control materials. Therefore, we conclude that the pressure microsensor is biocompatible.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/52536711" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="17aeaf2989719b4d277af6952d89a404" rel="nofollow" data-download="{"attachment_id":69758659,"asset_id":52536711,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69758659/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="89186" href="https://mayo.academia.edu/KentonKaufman">Kenton Kaufman</a><script data-card-contents-for-user="89186" type="text/json">{"id":89186,"first_name":"Kenton","last_name":"Kaufman","domain_name":"mayo","page_name":"KentonKaufman","display_name":"Kenton Kaufman","profile_url":"https://mayo.academia.edu/KentonKaufman?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_52536711 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="52536711"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 52536711, container: ".js-paper-rank-work_52536711", }); 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$(".js-view-count[data-work-id=52536711]").text(description); $(".js-view-count-work_52536711").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_52536711").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="52536711"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="524" rel="nofollow" href="https://www.academia.edu/Documents/in/Analytical_Chemistry">Analytical Chemistry</a>, <script data-card-contents-for-ri="524" type="text/json">{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="1131" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="17733" rel="nofollow" href="https://www.academia.edu/Documents/in/Nanotechnology">Nanotechnology</a><script data-card-contents-for-ri="17733" type="text/json">{"id":17733,"name":"Nanotechnology","url":"https://www.academia.edu/Documents/in/Nanotechnology?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=52536711]'), work: {"id":52536711,"title":"Biocompatibility of a physiological pressure sensor","created_at":"2021-09-16T12:28:58.735-07:00","url":"https://www.academia.edu/52536711/Biocompatibility_of_a_physiological_pressure_sensor?f_ri=71469","dom_id":"work_52536711","summary":"A newly developed fiber optic micropressure sensor was evaluated for biocompatibility using the International Organization for Standardization (ISO) test standard 10993-6. The test material and an inert control (fused silica glass) were tested in New Zealand white rabbits. Four test specimens were implanted in the paravertebral muscles on one side of the spine about 2 Á/5 cm from the midline and parallel to the spinal column. Similarly, four control specimens were implanted on the opposite side. The implantation periods were 1, 4, and 12 weeks to ensure a steady state biological tissue response. Four animals were tested at each time period. Macroscopic and microscopic observations were performed to compare the biological reactions between the test and control materials. There was an inflammatory reaction at 1 week which subsided at 4 weeks. There was fibrous tissue growth near the implant that also decreased over time. Most importantly, there was no significant difference in the biological response between the test and control materials. Therefore, we conclude that the pressure microsensor is biocompatible.","downloadable_attachments":[{"id":69758659,"asset_id":52536711,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":89186,"first_name":"Kenton","last_name":"Kaufman","domain_name":"mayo","page_name":"KentonKaufman","display_name":"Kenton Kaufman","profile_url":"https://mayo.academia.edu/KentonKaufman?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=71469","nofollow":true},{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=71469","nofollow":true},{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":17733,"name":"Nanotechnology","url":"https://www.academia.edu/Documents/in/Nanotechnology?f_ri=71469","nofollow":true},{"id":67357,"name":"Transducers","url":"https://www.academia.edu/Documents/in/Transducers?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":98440,"name":"Silica","url":"https://www.academia.edu/Documents/in/Silica?f_ri=71469"},{"id":234860,"name":"Steady state","url":"https://www.academia.edu/Documents/in/Steady_state?f_ri=71469"},{"id":404996,"name":"Optical fiber","url":"https://www.academia.edu/Documents/in/Optical_fiber?f_ri=71469"},{"id":443788,"name":"Glass Fiber","url":"https://www.academia.edu/Documents/in/Glass_Fiber?f_ri=71469"},{"id":571596,"name":"Pressure Sensor","url":"https://www.academia.edu/Documents/in/Pressure_Sensor?f_ri=71469"},{"id":580733,"name":"Fiber Optic","url":"https://www.academia.edu/Documents/in/Fiber_Optic?f_ri=71469"},{"id":788677,"name":"Rabbits","url":"https://www.academia.edu/Documents/in/Rabbits?f_ri=71469"},{"id":877397,"name":"Optical Fibers","url":"https://www.academia.edu/Documents/in/Optical_Fibers?f_ri=71469"},{"id":892969,"name":"Materials Testing","url":"https://www.academia.edu/Documents/in/Materials_Testing?f_ri=71469"},{"id":967566,"name":"Fiber Optic Technology","url":"https://www.academia.edu/Documents/in/Fiber_Optic_Technology?f_ri=71469"},{"id":1031069,"name":"Silicon Dioxide","url":"https://www.academia.edu/Documents/in/Silicon_Dioxide?f_ri=71469"},{"id":3536203,"name":"fused silica","url":"https://www.academia.edu/Documents/in/fused_silica?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_11477913" data-work_id="11477913" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/11477913/Fatty_Infiltration_in_the_Cervical_Extensor_Muscles_in_Persistent_Whiplash_Associated_Disorders_A_Magnetic_Resonance_Imaging_Analysis">Fatty Infiltration in the Cervical Extensor Muscles in Persistent Whiplash-Associated Disorders: A Magnetic Resonance Imaging Analysis</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Study Design. Cross-sectional investigation of muscle changes in patients suffering from persistent whiplashassociated disorders (WAD).</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/11477913" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="97898b89a5422ee86888ef7f3871aea8" rel="nofollow" data-download="{"attachment_id":46684095,"asset_id":11477913,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46684095/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="27955687" href="https://uq.academia.edu/GwendolenJull">Gwendolen Jull</a><script data-card-contents-for-user="27955687" type="text/json">{"id":27955687,"first_name":"Gwendolen","last_name":"Jull","domain_name":"uq","page_name":"GwendolenJull","display_name":"Gwendolen Jull","profile_url":"https://uq.academia.edu/GwendolenJull?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_11477913 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="11477913"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 11477913, container: ".js-paper-rank-work_11477913", }); 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$(".js-view-count[data-work-id=11477913]").text(description); $(".js-view-count-work_11477913").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_11477913").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="11477913"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1131" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="3132" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomechanics">Biomechanics</a>, <script data-card-contents-for-ri="3132" type="text/json">{"id":3132,"name":"Biomechanics","url":"https://www.academia.edu/Documents/in/Biomechanics?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4933" rel="nofollow" href="https://www.academia.edu/Documents/in/Spine">Spine</a>, <script data-card-contents-for-ri="4933" type="text/json">{"id":4933,"name":"Spine","url":"https://www.academia.edu/Documents/in/Spine?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a><script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=11477913]'), work: {"id":11477913,"title":"Fatty Infiltration in the Cervical Extensor Muscles in Persistent Whiplash-Associated Disorders: A Magnetic Resonance Imaging Analysis","created_at":"2015-03-17T01:23:17.595-07:00","url":"https://www.academia.edu/11477913/Fatty_Infiltration_in_the_Cervical_Extensor_Muscles_in_Persistent_Whiplash_Associated_Disorders_A_Magnetic_Resonance_Imaging_Analysis?f_ri=71469","dom_id":"work_11477913","summary":"Study Design. Cross-sectional investigation of muscle changes in patients suffering from persistent whiplashassociated disorders (WAD).","downloadable_attachments":[{"id":46684095,"asset_id":11477913,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":27955687,"first_name":"Gwendolen","last_name":"Jull","domain_name":"uq","page_name":"GwendolenJull","display_name":"Gwendolen Jull","profile_url":"https://uq.academia.edu/GwendolenJull?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=71469","nofollow":true},{"id":3132,"name":"Biomechanics","url":"https://www.academia.edu/Documents/in/Biomechanics?f_ri=71469","nofollow":true},{"id":4933,"name":"Spine","url":"https://www.academia.edu/Documents/in/Spine?f_ri=71469","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=71469","nofollow":true},{"id":8928,"name":"MRI","url":"https://www.academia.edu/Documents/in/MRI?f_ri=71469"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469"},{"id":52489,"name":"Adipose tissue","url":"https://www.academia.edu/Documents/in/Adipose_tissue?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":113960,"name":"Orthopedics","url":"https://www.academia.edu/Documents/in/Orthopedics?f_ri=71469"},{"id":186079,"name":"Cervical Vertebrae","url":"https://www.academia.edu/Documents/in/Cervical_Vertebrae?f_ri=71469"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469"},{"id":490954,"name":"Fat","url":"https://www.academia.edu/Documents/in/Fat?f_ri=71469"},{"id":723148,"name":"Cervical","url":"https://www.academia.edu/Documents/in/Cervical?f_ri=71469"},{"id":847989,"name":"Neck Muscles","url":"https://www.academia.edu/Documents/in/Neck_Muscles?f_ri=71469"},{"id":1034181,"name":"Cross Sectional Studies","url":"https://www.academia.edu/Documents/in/Cross_Sectional_Studies?f_ri=71469"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=71469"},{"id":2439414,"name":"Magnetic resonance image","url":"https://www.academia.edu/Documents/in/Magnetic_resonance_image?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_2046362" data-work_id="2046362" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/2046362/Muscle_plasticity_response_to_training_and_detraining">Muscle plasticity: response to training and detraining</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">All skeletal muscles have adaptive potential, which means that they are capable of modifying their structure in response to environmental change. Increased and reduced activity are two of the common environmental changes that... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_2046362" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">All skeletal muscles have adaptive potential, which means that they are capable of modifying their structure in response to environmental change. Increased and reduced activity are two of the common environmental changes that physiotherapists see in clinical practice (eg muscle training and detraining). The purpose of this article is to review the literature surrounding these two areas. Although many of the adaptations that occur in muscle as a result of increasing or reducing activity are reasonably well understood, there is still no consensus as to the best way either to promote or to prevent these adaptations. General principles for muscle training are accepted, but quantifying exercise prescription (eg in terms of duration, load or repetitions) is not standardised. One of the reasons for this lack of standardisation is the individuality of each person's response to exercise, some of which may be explained by genetic factors. Recent studies have explored the effect of the angiotensin converting enzyme genotype on physical performance, with some conflicting results.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2046362" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="32f5d6dc6ef4710fa072565fe3500c8d" rel="nofollow" data-download="{"attachment_id":29576035,"asset_id":2046362,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/29576035/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="271229" href="https://soton.academia.edu/AnneBruton">Anne Bruton</a><script data-card-contents-for-user="271229" type="text/json">{"id":271229,"first_name":"Anne","last_name":"Bruton","domain_name":"soton","page_name":"AnneBruton","display_name":"Anne Bruton","profile_url":"https://soton.academia.edu/AnneBruton?f_ri=71469","photo":"https://0.academia-photos.com/271229/56409/57953/s65_anne.bruton.271229"}</script></span></span></li><li class="js-paper-rank-work_2046362 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="2046362"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 2046362, container: ".js-paper-rank-work_2046362", }); 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$(".js-view-count[data-work-id=2046362]").text(description); $(".js-view-count-work_2046362").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2046362").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2046362"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="593" rel="nofollow" href="https://www.academia.edu/Documents/in/Physiotherapy">Physiotherapy</a>, <script data-card-contents-for-ri="593" type="text/json">{"id":593,"name":"Physiotherapy","url":"https://www.academia.edu/Documents/in/Physiotherapy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=2046362]'), work: {"id":2046362,"title":"Muscle plasticity: response to training and detraining","created_at":"2012-10-21T04:12:01.966-07:00","url":"https://www.academia.edu/2046362/Muscle_plasticity_response_to_training_and_detraining?f_ri=71469","dom_id":"work_2046362","summary":"All skeletal muscles have adaptive potential, which means that they are capable of modifying their structure in response to environmental change. Increased and reduced activity are two of the common environmental changes that physiotherapists see in clinical practice (eg muscle training and detraining). The purpose of this article is to review the literature surrounding these two areas. Although many of the adaptations that occur in muscle as a result of increasing or reducing activity are reasonably well understood, there is still no consensus as to the best way either to promote or to prevent these adaptations. General principles for muscle training are accepted, but quantifying exercise prescription (eg in terms of duration, load or repetitions) is not standardised. One of the reasons for this lack of standardisation is the individuality of each person's response to exercise, some of which may be explained by genetic factors. Recent studies have explored the effect of the angiotensin converting enzyme genotype on physical performance, with some conflicting results.","downloadable_attachments":[{"id":29576035,"asset_id":2046362,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":271229,"first_name":"Anne","last_name":"Bruton","domain_name":"soton","page_name":"AnneBruton","display_name":"Anne Bruton","profile_url":"https://soton.academia.edu/AnneBruton?f_ri=71469","photo":"https://0.academia-photos.com/271229/56409/57953/s65_anne.bruton.271229"}],"research_interests":[{"id":593,"name":"Physiotherapy","url":"https://www.academia.edu/Documents/in/Physiotherapy?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_56651876" data-work_id="56651876" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/56651876/Elevated_endogenous_testosterone_concentrations_potentiate_muscle_androgen_receptor_responses_to_resistance_exercise">Elevated endogenous testosterone concentrations potentiate muscle androgen receptor responses to resistance exercise</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The purpose of this study was to determine the influence of endogenous circulating testosterone (T) on muscle androgen receptor (AR) responses to acute resistance exercise (RE). Six healthy men (26 ± 4 years; 176 ± 5 cm; 75.8 ± 11.4 kg)... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_56651876" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The purpose of this study was to determine the influence of endogenous circulating testosterone (T) on muscle androgen receptor (AR) responses to acute resistance exercise (RE). Six healthy men (26 ± 4 years; 176 ± 5 cm; 75.8 ± 11.4 kg) performed a knee extension exercise protocol on two occasions separated by 1-3 weeks. Rest preceded one trial (i.e., control [CON] trial) and a high-volume upper-body RE protocol designed to increase circulating T preceded the other trial (i.e., high T [HT] trial). Serial blood samples were obtained throughout each trial to determine circulating T concentrations. Biopsies of the vastus lateralis were obtained pre-RE (REST), 10-min post-RE (+10), and 180-min post-RE (+180) to determine muscle AR content. Circulating T concentrations remained stable during CON. Alternately, HT significantly (p ≤ 0.05) increased T concentrations above resting values (+16%). Testosterone area-under-the-time curve during HT exceeded CON by 14%. AR content remained stable from REST to +10 in both trials. Compared to the corresponding +10 value, muscle AR content at +180 tended to decrease during CON (−33%; p = 0.10) but remained stable during HT (+40%; p = 0.17). Muscle AR content at +180 during the HT trial exceeded the corresponding CON value. In conclusion, acute elevations in circulating T potentiated muscle AR content following RE.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/56651876" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4f8431f716695e7a5c0043e3288d260b" rel="nofollow" data-download="{"attachment_id":71933057,"asset_id":56651876,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/71933057/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36417321" href="https://independent.academia.edu/WilliamKraemer">William Kraemer</a><script data-card-contents-for-user="36417321" type="text/json">{"id":36417321,"first_name":"William","last_name":"Kraemer","domain_name":"independent","page_name":"WilliamKraemer","display_name":"William Kraemer","profile_url":"https://independent.academia.edu/WilliamKraemer?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_56651876 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="56651876"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 56651876, container: ".js-paper-rank-work_56651876", }); });</script></li><li class="js-percentile-work_56651876 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 56651876; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_56651876"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_56651876 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="56651876"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 56651876; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=56651876]").text(description); $(".js-view-count-work_56651876").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_56651876").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="56651876"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="19883" rel="nofollow" href="https://www.academia.edu/Documents/in/Protocol_Design">Protocol Design</a>, <script data-card-contents-for-ri="19883" type="text/json">{"id":19883,"name":"Protocol Design","url":"https://www.academia.edu/Documents/in/Protocol_Design?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="42130" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_Receptor">Nuclear Receptor</a>, <script data-card-contents-for-ri="42130" type="text/json">{"id":42130,"name":"Nuclear Receptor","url":"https://www.academia.edu/Documents/in/Nuclear_Receptor?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="69056" rel="nofollow" href="https://www.academia.edu/Documents/in/Testosterone">Testosterone</a>, <script data-card-contents-for-ri="69056" type="text/json">{"id":69056,"name":"Testosterone","url":"https://www.academia.edu/Documents/in/Testosterone?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a><script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=56651876]'), work: {"id":56651876,"title":"Elevated endogenous testosterone concentrations potentiate muscle androgen receptor responses to resistance exercise","created_at":"2021-10-08T14:19:39.366-07:00","url":"https://www.academia.edu/56651876/Elevated_endogenous_testosterone_concentrations_potentiate_muscle_androgen_receptor_responses_to_resistance_exercise?f_ri=71469","dom_id":"work_56651876","summary":"The purpose of this study was to determine the influence of endogenous circulating testosterone (T) on muscle androgen receptor (AR) responses to acute resistance exercise (RE). Six healthy men (26 ± 4 years; 176 ± 5 cm; 75.8 ± 11.4 kg) performed a knee extension exercise protocol on two occasions separated by 1-3 weeks. Rest preceded one trial (i.e., control [CON] trial) and a high-volume upper-body RE protocol designed to increase circulating T preceded the other trial (i.e., high T [HT] trial). Serial blood samples were obtained throughout each trial to determine circulating T concentrations. Biopsies of the vastus lateralis were obtained pre-RE (REST), 10-min post-RE (+10), and 180-min post-RE (+180) to determine muscle AR content. Circulating T concentrations remained stable during CON. Alternately, HT significantly (p ≤ 0.05) increased T concentrations above resting values (+16%). Testosterone area-under-the-time curve during HT exceeded CON by 14%. AR content remained stable from REST to +10 in both trials. Compared to the corresponding +10 value, muscle AR content at +180 tended to decrease during CON (−33%; p = 0.10) but remained stable during HT (+40%; p = 0.17). Muscle AR content at +180 during the HT trial exceeded the corresponding CON value. In conclusion, acute elevations in circulating T potentiated muscle AR content following RE.","downloadable_attachments":[{"id":71933057,"asset_id":56651876,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36417321,"first_name":"William","last_name":"Kraemer","domain_name":"independent","page_name":"WilliamKraemer","display_name":"William Kraemer","profile_url":"https://independent.academia.edu/WilliamKraemer?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":19883,"name":"Protocol Design","url":"https://www.academia.edu/Documents/in/Protocol_Design?f_ri=71469","nofollow":true},{"id":42130,"name":"Nuclear Receptor","url":"https://www.academia.edu/Documents/in/Nuclear_Receptor?f_ri=71469","nofollow":true},{"id":69056,"name":"Testosterone","url":"https://www.academia.edu/Documents/in/Testosterone?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":103298,"name":"Blood sampling","url":"https://www.academia.edu/Documents/in/Blood_sampling?f_ri=71469"},{"id":126964,"name":"Endocrine","url":"https://www.academia.edu/Documents/in/Endocrine?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":380006,"name":"Rest","url":"https://www.academia.edu/Documents/in/Rest?f_ri=71469"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=71469"},{"id":445233,"name":"Hormone","url":"https://www.academia.edu/Documents/in/Hormone?f_ri=71469"},{"id":452368,"name":"Anabolic","url":"https://www.academia.edu/Documents/in/Anabolic?f_ri=71469"},{"id":590252,"name":"Androgen Receptor","url":"https://www.academia.edu/Documents/in/Androgen_Receptor?f_ri=71469"},{"id":771538,"name":"Resistance Exercise","url":"https://www.academia.edu/Documents/in/Resistance_Exercise?f_ri=71469"},{"id":1277406,"name":"Knee Extension","url":"https://www.academia.edu/Documents/in/Knee_Extension?f_ri=71469"},{"id":1309706,"name":"Area Under Curve","url":"https://www.academia.edu/Documents/in/Area_Under_Curve?f_ri=71469"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=71469"},{"id":4002193,"name":"Macho","url":"https://www.academia.edu/Documents/in/Macho?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33221686" data-work_id="33221686" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33221686/Muscle_phosphofructokinase_deficiency_Two_cases_with_unusual_polysaccharide_accumulation_and_immunologically_active_enzyme_protein">Muscle phosphofructokinase deficiency: Two cases with unusual polysaccharide accumulation and immunologically active enzyme protein</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Two patients with phosphofructokinase (PFK) deficiency had exercise intolerance and increased serum activity of creatine kinase; one presented with hemolytic anemia, hyperuricemia, and gouty arthritis. The glycogen concentration in the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_33221686" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Two patients with phosphofructokinase (PFK) deficiency had exercise intolerance and increased serum activity of creatine kinase; one presented with hemolytic anemia, hyperuricemia, and gouty arthritis. The glycogen concentration in the muscle of these patients was about twice normal. PFK activity was virtually absent in muscle, but antibodies against the M subunits of the normal human PFK showed cross-reacting material in muscle from both patients. The PFK level in red blood cells, studied in one case, was lower than normal in the patient and both parents. Morphologically, there was extensive deposition of normal glycogen underneath the sarcolemma and in the intermyofibrillar space. In addition, 2% to 3% of the myofibers contained hyaline, PAS-positive, diastase-resistant inclusions that had a filamentous fine structure: histochemical reactions suggested an insoluble form of glycogen. Similar inclusions have not been described previously in PFK deficiency. Accumulation of an abnormal polysaccharide in muscle may be due to a second undiscovered enzymatic defect or may be a metabolic consequence of PFK deficiency.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33221686" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b0c86492157a51ca81c5c1c2cce100db" rel="nofollow" data-download="{"attachment_id":53298725,"asset_id":33221686,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53298725/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="54101819" href="https://independent.academia.edu/aliaskari11">ali askari</a><script data-card-contents-for-user="54101819" type="text/json">{"id":54101819,"first_name":"ali","last_name":"askari","domain_name":"independent","page_name":"aliaskari11","display_name":"ali askari","profile_url":"https://independent.academia.edu/aliaskari11?f_ri=71469","photo":"https://0.academia-photos.com/54101819/19943819/19742176/s65_ali.askari.jpg"}</script></span></span></li><li class="js-paper-rank-work_33221686 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33221686"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33221686, container: ".js-paper-rank-work_33221686", }); 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$(".js-view-count[data-work-id=33221686]").text(description); $(".js-view-count-work_33221686").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33221686").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33221686"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="2184" rel="nofollow" href="https://www.academia.edu/Documents/in/Electron_Microscopy">Electron Microscopy</a>, <script data-card-contents-for-ri="2184" type="text/json">{"id":2184,"name":"Electron Microscopy","url":"https://www.academia.edu/Documents/in/Electron_Microscopy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37826" rel="nofollow" href="https://www.academia.edu/Documents/in/Biopsy">Biopsy</a>, <script data-card-contents-for-ri="37826" type="text/json">{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71476" rel="nofollow" href="https://www.academia.edu/Documents/in/Phosphofructokinase">Phosphofructokinase</a><script data-card-contents-for-ri="71476" type="text/json">{"id":71476,"name":"Phosphofructokinase","url":"https://www.academia.edu/Documents/in/Phosphofructokinase?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33221686]'), work: {"id":33221686,"title":"Muscle phosphofructokinase deficiency: Two cases with unusual polysaccharide accumulation and immunologically active enzyme protein","created_at":"2017-05-27T12:10:52.469-07:00","url":"https://www.academia.edu/33221686/Muscle_phosphofructokinase_deficiency_Two_cases_with_unusual_polysaccharide_accumulation_and_immunologically_active_enzyme_protein?f_ri=71469","dom_id":"work_33221686","summary":"Two patients with phosphofructokinase (PFK) deficiency had exercise intolerance and increased serum activity of creatine kinase; one presented with hemolytic anemia, hyperuricemia, and gouty arthritis. The glycogen concentration in the muscle of these patients was about twice normal. PFK activity was virtually absent in muscle, but antibodies against the M subunits of the normal human PFK showed cross-reacting material in muscle from both patients. The PFK level in red blood cells, studied in one case, was lower than normal in the patient and both parents. Morphologically, there was extensive deposition of normal glycogen underneath the sarcolemma and in the intermyofibrillar space. In addition, 2% to 3% of the myofibers contained hyaline, PAS-positive, diastase-resistant inclusions that had a filamentous fine structure: histochemical reactions suggested an insoluble form of glycogen. Similar inclusions have not been described previously in PFK deficiency. Accumulation of an abnormal polysaccharide in muscle may be due to a second undiscovered enzymatic defect or may be a metabolic consequence of PFK deficiency.","downloadable_attachments":[{"id":53298725,"asset_id":33221686,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":54101819,"first_name":"ali","last_name":"askari","domain_name":"independent","page_name":"aliaskari11","display_name":"ali askari","profile_url":"https://independent.academia.edu/aliaskari11?f_ri=71469","photo":"https://0.academia-photos.com/54101819/19943819/19742176/s65_ali.askari.jpg"}],"research_interests":[{"id":2184,"name":"Electron 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})();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_2004176" data-work_id="2004176" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/2004176/The_effect_of_progressive_resistance_training_on_leg_strength_aerobic_capacity_and_functional_tasks_of_daily_living_in_persons_with_Down_syndrome">The effect of progressive resistance training on leg strength, aerobic capacity and functional tasks of daily living in persons with Down syndrome</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2004176" 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description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=2004176]").text(description); $(".js-view-count-work_2004176").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2004176").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2004176"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="34802" rel="nofollow" href="https://www.academia.edu/Documents/in/Disability">Disability</a>, <script data-card-contents-for-ri="34802" type="text/json">{"id":34802,"name":"Disability","url":"https://www.academia.edu/Documents/in/Disability?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37413" rel="nofollow" href="https://www.academia.edu/Documents/in/Down_Syndrome">Down Syndrome</a>, <script data-card-contents-for-ri="37413" type="text/json">{"id":37413,"name":"Down Syndrome","url":"https://www.academia.edu/Documents/in/Down_Syndrome?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44529" rel="nofollow" href="https://www.academia.edu/Documents/in/Activities_of_Daily_Living">Activities of Daily 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syndrome","created_at":"2012-10-07T12:04:00.811-07:00","url":"https://www.academia.edu/2004176/The_effect_of_progressive_resistance_training_on_leg_strength_aerobic_capacity_and_functional_tasks_of_daily_living_in_persons_with_Down_syndrome?f_ri=71469","dom_id":"work_2004176","summary":null,"downloadable_attachments":[{"id":50791663,"asset_id":2004176,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":2614372,"first_name":"Sharon","last_name":"Hsu","domain_name":"csun","page_name":"SharonHsu","display_name":"Sharon Hsu","profile_url":"https://csun.academia.edu/SharonHsu?f_ri=71469","photo":"https://0.academia-photos.com/2614372/106873700/96087765/s65_sharon.hsu.jpg"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469","nofollow":true},{"id":34802,"name":"Disability","url":"https://www.academia.edu/Documents/in/Disability?f_ri=71469","nofollow":true},{"id":37413,"name":"Down Syndrome","url":"https://www.academia.edu/Documents/in/Down_Syndrome?f_ri=71469","nofollow":true},{"id":44529,"name":"Activities of Daily Living","url":"https://www.academia.edu/Documents/in/Activities_of_Daily_Living?f_ri=71469","nofollow":true},{"id":44530,"name":"Muscle strength","url":"https://www.academia.edu/Documents/in/Muscle_strength?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":112275,"name":"Resistance Training","url":"https://www.academia.edu/Documents/in/Resistance_Training?f_ri=71469"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=71469"},{"id":135185,"name":"Exercise","url":"https://www.academia.edu/Documents/in/Exercise?f_ri=71469"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=71469"},{"id":462777,"name":"Leg","url":"https://www.academia.edu/Documents/in/Leg?f_ri=71469"},{"id":1210716,"name":"Exercise Tolerance","url":"https://www.academia.edu/Documents/in/Exercise_Tolerance?f_ri=71469"},{"id":1272890,"name":"Electric Impedance","url":"https://www.academia.edu/Documents/in/Electric_Impedance?f_ri=71469"},{"id":2058719,"name":"Isometric Contraction","url":"https://www.academia.edu/Documents/in/Isometric_Contraction?f_ri=71469"},{"id":2183225,"name":"Physical Endurance","url":"https://www.academia.edu/Documents/in/Physical_Endurance?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22125615 coauthored" data-work_id="22125615" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22125615/Insulin_effects_in_muscle_and_adipose_tissue">Insulin effects in muscle and adipose tissue</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Insulin Muscle Adipose tissue Non-esterified fatty acids Hexokinase 6-phosphofructokinase The major effects of insulin on muscle and adipose tissue are: (1) Carbohydrate metabolism: (a) it increases the rate of glucose transport across... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22125615" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Insulin Muscle Adipose tissue Non-esterified fatty acids Hexokinase 6-phosphofructokinase The major effects of insulin on muscle and adipose tissue are: (1) Carbohydrate metabolism: (a) it increases the rate of glucose transport across the cell membrane, (b) it increases the rate of glycolysis by increasing hexokinase and 6-phosphofructokinase activity, (c) it stimulates the rate of glycogen synthesis and decreases the rate of glycogen breakdown. (2) Lipid metabolism: (a) it decreases the rate of lipolysis in adipose tissue and hence lowers the plasma fatty acid level, (b) it stimulates fatty acid and triacylglycerol synthesis in tissues, (c) it increases the uptake of triglycerides from the blood into adipose tissue and muscle, (d) it decreases the rate of fatty acid oxidation in muscle and liver. (3) Protein metabolism: (a) it increases the rate of transport of some amino acids into tissues, (b) it increases the rate of protein synthesis in muscle, adipose tissue, liver, and other tissues, (c) it decreases the rate of protein degradation in muscle (and perhaps other tissues).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22125615" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0f9562ea80fcbd09ff331f3c5094138d" rel="nofollow" data-download="{"attachment_id":42793676,"asset_id":22125615,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42793676/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="42040749" href="https://independent.academia.edu/EiriniMaratou">Eirini Maratou</a><script data-card-contents-for-user="42040749" type="text/json">{"id":42040749,"first_name":"Eirini","last_name":"Maratou","domain_name":"independent","page_name":"EiriniMaratou","display_name":"Eirini Maratou","profile_url":"https://independent.academia.edu/EiriniMaratou?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-22125615">+1</span><div class="hidden js-additional-users-22125615"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/PanayotaMitrou">Panayota Mitrou</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-22125615'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-22125615').html(); 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container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22125615 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22125615"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22125615; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22125615]").text(description); $(".js-view-count-work_22125615").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22125615").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22125615"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4581" rel="nofollow" href="https://www.academia.edu/Documents/in/Diabetes">Diabetes</a>, <script data-card-contents-for-ri="4581" type="text/json">{"id":4581,"name":"Diabetes","url":"https://www.academia.edu/Documents/in/Diabetes?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="38139" rel="nofollow" href="https://www.academia.edu/Documents/in/Protein_synthesis">Protein synthesis</a>, <script data-card-contents-for-ri="38139" type="text/json">{"id":38139,"name":"Protein synthesis","url":"https://www.academia.edu/Documents/in/Protein_synthesis?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="52489" rel="nofollow" href="https://www.academia.edu/Documents/in/Adipose_tissue">Adipose tissue</a>, <script data-card-contents-for-ri="52489" type="text/json">{"id":52489,"name":"Adipose tissue","url":"https://www.academia.edu/Documents/in/Adipose_tissue?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71400" rel="nofollow" href="https://www.academia.edu/Documents/in/Insulin">Insulin</a><script data-card-contents-for-ri="71400" type="text/json">{"id":71400,"name":"Insulin","url":"https://www.academia.edu/Documents/in/Insulin?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22125615]'), work: {"id":22125615,"title":"Insulin effects in muscle and adipose tissue","created_at":"2016-02-18T01:27:59.555-08:00","url":"https://www.academia.edu/22125615/Insulin_effects_in_muscle_and_adipose_tissue?f_ri=71469","dom_id":"work_22125615","summary":"Insulin Muscle Adipose tissue Non-esterified fatty acids Hexokinase 6-phosphofructokinase The major effects of insulin on muscle and adipose tissue are: (1) Carbohydrate metabolism: (a) it increases the rate of glucose transport across the cell membrane, (b) it increases the rate of glycolysis by increasing hexokinase and 6-phosphofructokinase activity, (c) it stimulates the rate of glycogen synthesis and decreases the rate of glycogen breakdown. (2) Lipid metabolism: (a) it decreases the rate of lipolysis in adipose tissue and hence lowers the plasma fatty acid level, (b) it stimulates fatty acid and triacylglycerol synthesis in tissues, (c) it increases the uptake of triglycerides from the blood into adipose tissue and muscle, (d) it decreases the rate of fatty acid oxidation in muscle and liver. (3) Protein metabolism: (a) it increases the rate of transport of some amino acids into tissues, (b) it increases the rate of protein synthesis in muscle, adipose tissue, liver, and other tissues, (c) it decreases the rate of protein degradation in muscle (and perhaps other tissues).","downloadable_attachments":[{"id":42793676,"asset_id":22125615,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42040749,"first_name":"Eirini","last_name":"Maratou","domain_name":"independent","page_name":"EiriniMaratou","display_name":"Eirini Maratou","profile_url":"https://independent.academia.edu/EiriniMaratou?f_ri=71469","photo":"/images/s65_no_pic.png"},{"id":43452664,"first_name":"Panayota","last_name":"Mitrou","domain_name":"independent","page_name":"PanayotaMitrou","display_name":"Panayota Mitrou","profile_url":"https://independent.academia.edu/PanayotaMitrou?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4581,"name":"Diabetes","url":"https://www.academia.edu/Documents/in/Diabetes?f_ri=71469","nofollow":true},{"id":38139,"name":"Protein synthesis","url":"https://www.academia.edu/Documents/in/Protein_synthesis?f_ri=71469","nofollow":true},{"id":52489,"name":"Adipose tissue","url":"https://www.academia.edu/Documents/in/Adipose_tissue?f_ri=71469","nofollow":true},{"id":71400,"name":"Insulin","url":"https://www.academia.edu/Documents/in/Insulin?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":127955,"name":"Fatty Acid Oxidation","url":"https://www.academia.edu/Documents/in/Fatty_Acid_Oxidation?f_ri=71469"},{"id":134095,"name":"Muscles","url":"https://www.academia.edu/Documents/in/Muscles?f_ri=71469"},{"id":184609,"name":"Lipid metabolism","url":"https://www.academia.edu/Documents/in/Lipid_metabolism?f_ri=71469"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=71469"},{"id":306952,"name":"Glucose Transport","url":"https://www.academia.edu/Documents/in/Glucose_Transport?f_ri=71469"},{"id":311112,"name":"Protein Metabolism","url":"https://www.academia.edu/Documents/in/Protein_Metabolism?f_ri=71469"},{"id":409525,"name":"Carbohydrate metabolism","url":"https://www.academia.edu/Documents/in/Carbohydrate_metabolism?f_ri=71469"},{"id":486713,"name":"Fatty Acid","url":"https://www.academia.edu/Documents/in/Fatty_Acid?f_ri=71469"},{"id":500737,"name":"Protein Degradation","url":"https://www.academia.edu/Documents/in/Protein_Degradation?f_ri=71469"},{"id":585573,"name":"Amino Acid Profile","url":"https://www.academia.edu/Documents/in/Amino_Acid_Profile?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22561131" data-work_id="22561131" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22561131/Relationship_Between_Off_Flavor_Descriptors_and_Flavor_Scores_in_Beef_From_Cattle_Raised_on_Natural_Pasture">Relationship Between Off-Flavor Descriptors and Flavor Scores in Beef From Cattle Raised on Natural Pasture</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The current study determined the relationship between off-flavour descriptors and flavour scores in beef aged for two and 21 days from Nguni, Bonsmara and Angus steers. Fifteen steers each of Bonsmara and Angus and 25 steers of Nguni were... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22561131" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The current study determined the relationship between off-flavour descriptors and flavour scores in beef aged for two and 21 days from Nguni, Bonsmara and Angus steers. Fifteen steers each of Bonsmara and Angus and 25 steers of Nguni were slaughtered at 18 months. The m. longissimus thoracis et lumborum was sampled post mortem for flavour evaluation. There were associations between off-flavour descriptors and off-flavour scores, off-flavour descriptors and aroma scores. There were no associations between beef from the three cattle breeds and off-flavour descriptors, flavour scores and off-flavour descriptors, ageing periods and off-flavour descriptors. It can be concluded that off-flavour description is uniform across breeds and ageing periods. Furthermore, off-flavour description is related to off-flavour scores and aroma scores.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22561131" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9e340e77d8b124ce8d275b43bdbc798f" rel="nofollow" data-download="{"attachment_id":43171333,"asset_id":22561131,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43171333/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44102312" href="https://independent.academia.edu/PhillipStrydom">Phillip Strydom</a><script data-card-contents-for-user="44102312" type="text/json">{"id":44102312,"first_name":"Phillip","last_name":"Strydom","domain_name":"independent","page_name":"PhillipStrydom","display_name":"Phillip Strydom","profile_url":"https://independent.academia.edu/PhillipStrydom?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22561131 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22561131"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22561131, container: ".js-paper-rank-work_22561131", }); });</script></li><li class="js-percentile-work_22561131 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22561131; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22561131"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22561131 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22561131"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22561131; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22561131]").text(description); $(".js-view-count-work_22561131").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22561131").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22561131"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">2</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="573653" rel="nofollow" href="https://www.academia.edu/Documents/in/Food_Sciences">Food Sciences</a><script data-card-contents-for-ri="573653" type="text/json">{"id":573653,"name":"Food Sciences","url":"https://www.academia.edu/Documents/in/Food_Sciences?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22561131]'), work: {"id":22561131,"title":"Relationship Between Off-Flavor Descriptors and Flavor Scores in Beef From Cattle Raised on Natural Pasture","created_at":"2016-02-28T13:00:59.308-08:00","url":"https://www.academia.edu/22561131/Relationship_Between_Off_Flavor_Descriptors_and_Flavor_Scores_in_Beef_From_Cattle_Raised_on_Natural_Pasture?f_ri=71469","dom_id":"work_22561131","summary":"The current study determined the relationship between off-flavour descriptors and flavour scores in beef aged for two and 21 days from Nguni, Bonsmara and Angus steers. Fifteen steers each of Bonsmara and Angus and 25 steers of Nguni were slaughtered at 18 months. The m. longissimus thoracis et lumborum was sampled post mortem for flavour evaluation. There were associations between off-flavour descriptors and off-flavour scores, off-flavour descriptors and aroma scores. There were no associations between beef from the three cattle breeds and off-flavour descriptors, flavour scores and off-flavour descriptors, ageing periods and off-flavour descriptors. It can be concluded that off-flavour description is uniform across breeds and ageing periods. Furthermore, off-flavour description is related to off-flavour scores and aroma scores.","downloadable_attachments":[{"id":43171333,"asset_id":22561131,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44102312,"first_name":"Phillip","last_name":"Strydom","domain_name":"independent","page_name":"PhillipStrydom","display_name":"Phillip Strydom","profile_url":"https://independent.academia.edu/PhillipStrydom?f_ri=71469","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":573653,"name":"Food Sciences","url":"https://www.academia.edu/Documents/in/Food_Sciences?f_ri=71469","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_30487028" data-work_id="30487028" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/30487028/The_transition_from_thinness_oriented_to_muscularity_oriented_disordered_eating_in_adolescent_males_A_clinical_observation">The transition from thinness-oriented to muscularity-oriented disordered eating in adolescent males: A clinical observation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: Robust empirical evidence has illustrated a rising prevalence of body dissatisfaction and disordered eating among males, noting that both may be oriented more toward muscularity as opposed to thinness-oriented concerns. While an... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_30487028" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: Robust empirical evidence has illustrated a rising prevalence of body dissatisfaction and disordered eating among males, noting that both may be oriented more toward muscularity as opposed to thinness-oriented concerns. While an elevated prevalence of premorbid anorexia nervosa (AN) has been noted among those with muscle dysmorphia, little evidence has examined the process of this transition from thinness-oriented to muscularity-oriented disordered eating. <br /><br />Methods: This clinical observation presents a case of AN in an adolescent male, whose symptom presentation transitioned during the course of treatment for AN, into more muscularity-oriented disordered eating. <br /><br />Results: Despite the core body image disturbance and disordered eating behaviors being retained, the behavioral expression of muscularity-oriented disordered eating was difficult to detect during treatment for AN, and he was discharged from treatment as his muscularity-oriented disordered eating escalated. <br /><br />Conclusions: Transdiagnostic crossover between thinness-oriented and muscularity-oriented disordered eating represents an important clinical concern, which may be challenging to measure and assess. Implications for treatment are discussed, and the early detection of muscularity-oriented disordered eating.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30487028" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="456309af3d2bbfadce2cf6b1d60bd1bc" rel="nofollow" data-download="{"attachment_id":50925654,"asset_id":30487028,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50925654/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3292576" href="https://unimelb.academia.edu/ScottGriffiths">Scott Griffiths</a><script data-card-contents-for-user="3292576" type="text/json">{"id":3292576,"first_name":"Scott","last_name":"Griffiths","domain_name":"unimelb","page_name":"ScottGriffiths","display_name":"Scott Griffiths","profile_url":"https://unimelb.academia.edu/ScottGriffiths?f_ri=71469","photo":"https://0.academia-photos.com/3292576/1094355/19390071/s65_scott.griffiths.png"}</script></span></span></li><li class="js-paper-rank-work_30487028 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="30487028"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 30487028, container: ".js-paper-rank-work_30487028", }); });</script></li><li class="js-percentile-work_30487028 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 30487028; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_30487028"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_30487028 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="30487028"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 30487028; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=30487028]").text(description); $(".js-view-count-work_30487028").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_30487028").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="30487028"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="221" rel="nofollow" href="https://www.academia.edu/Documents/in/Psychology">Psychology</a>, <script data-card-contents-for-ri="221" type="text/json">{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="226" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Psychology">Clinical Psychology</a>, <script data-card-contents-for-ri="226" type="text/json">{"id":226,"name":"Clinical Psychology","url":"https://www.academia.edu/Documents/in/Clinical_Psychology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2625" rel="nofollow" href="https://www.academia.edu/Documents/in/Child_and_adolescent_mental_health">Child and adolescent mental health</a>, <script data-card-contents-for-ri="2625" type="text/json">{"id":2625,"name":"Child and adolescent mental health","url":"https://www.academia.edu/Documents/in/Child_and_adolescent_mental_health?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2827" rel="nofollow" href="https://www.academia.edu/Documents/in/Mental_Health">Mental Health</a><script data-card-contents-for-ri="2827" type="text/json">{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=30487028]'), work: {"id":30487028,"title":"The transition from thinness-oriented to muscularity-oriented disordered eating in adolescent males: A clinical observation","created_at":"2016-12-16T13:34:34.323-08:00","url":"https://www.academia.edu/30487028/The_transition_from_thinness_oriented_to_muscularity_oriented_disordered_eating_in_adolescent_males_A_clinical_observation?f_ri=71469","dom_id":"work_30487028","summary":"Purpose: Robust empirical evidence has illustrated a rising prevalence of body dissatisfaction and disordered eating among males, noting that both may be oriented more toward muscularity as opposed to thinness-oriented concerns. While an elevated prevalence of premorbid anorexia nervosa (AN) has been noted among those with muscle dysmorphia, little evidence has examined the process of this transition from thinness-oriented to muscularity-oriented disordered eating. \n\nMethods: This clinical observation presents a case of AN in an adolescent male, whose symptom presentation transitioned during the course of treatment for AN, into more muscularity-oriented disordered eating. \n\nResults: Despite the core body image disturbance and disordered eating behaviors being retained, the behavioral expression of muscularity-oriented disordered eating was difficult to detect during treatment for AN, and he was discharged from treatment as his muscularity-oriented disordered eating escalated. \n\nConclusions: Transdiagnostic crossover between thinness-oriented and muscularity-oriented disordered eating represents an important clinical concern, which may be challenging to measure and assess. Implications for treatment are discussed, and the early detection of muscularity-oriented disordered eating.","downloadable_attachments":[{"id":50925654,"asset_id":30487028,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3292576,"first_name":"Scott","last_name":"Griffiths","domain_name":"unimelb","page_name":"ScottGriffiths","display_name":"Scott Griffiths","profile_url":"https://unimelb.academia.edu/ScottGriffiths?f_ri=71469","photo":"https://0.academia-photos.com/3292576/1094355/19390071/s65_scott.griffiths.png"}],"research_interests":[{"id":221,"name":"Psychology","url":"https://www.academia.edu/Documents/in/Psychology?f_ri=71469","nofollow":true},{"id":226,"name":"Clinical Psychology","url":"https://www.academia.edu/Documents/in/Clinical_Psychology?f_ri=71469","nofollow":true},{"id":2625,"name":"Child and adolescent mental health","url":"https://www.academia.edu/Documents/in/Child_and_adolescent_mental_health?f_ri=71469","nofollow":true},{"id":2827,"name":"Mental Health","url":"https://www.academia.edu/Documents/in/Mental_Health?f_ri=71469","nofollow":true},{"id":3279,"name":"Psychotherapy and Counseling","url":"https://www.academia.edu/Documents/in/Psychotherapy_and_Counseling?f_ri=71469"},{"id":4160,"name":"Eating Disorders","url":"https://www.academia.edu/Documents/in/Eating_Disorders?f_ri=71469"},{"id":21268,"name":"Muscle Dysmorphia","url":"https://www.academia.edu/Documents/in/Muscle_Dysmorphia?f_ri=71469"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":487114,"name":"Disordered Eating","url":"https://www.academia.edu/Documents/in/Disordered_Eating?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_47633449" data-work_id="47633449" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/47633449/Muscle_injuries_diagnostics_and_treatments">Muscle injuries: diagnostics and treatments</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Verletzungen des Skelettmuskels gehören mit 10-55% zu den häufigsten Sportverletzungen überhaupt [7, 22, 32]. Sie können aufgrund von außen einwirkender Gewalt (Traumen) oder durch verschiedene innere Ursachen (Stoffwechsel, Vorschädigung... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_47633449" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Verletzungen des Skelettmuskels gehören mit 10-55% zu den häufigsten Sportverletzungen überhaupt [7, 22, 32]. Sie können aufgrund von außen einwirkender Gewalt (Traumen) oder durch verschiedene innere Ursachen (Stoffwechsel, Vorschädigung etc.) hervorgerufen werden. Dabei kommt es zu einem Missverhältnis zwischen Belastung und Belastbarkeit, was posttraumatisch innerhalb eines bestimmten Regenerationszeitraums (Stunden bis Wochen) zu einer Funktionseinschränkung der Muskulatur führt.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/47633449" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9828508627d263695667a4618b55e584" rel="nofollow" data-download="{"attachment_id":66626047,"asset_id":47633449,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/66626047/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="40502273" href="https://independent.academia.edu/olaflorbach">olaf lorbach</a><script data-card-contents-for-user="40502273" type="text/json">{"id":40502273,"first_name":"olaf","last_name":"lorbach","domain_name":"independent","page_name":"olaflorbach","display_name":"olaf lorbach","profile_url":"https://independent.academia.edu/olaflorbach?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_47633449 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="47633449"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 47633449, container: ".js-paper-rank-work_47633449", }); 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Sie können aufgrund von außen einwirkender Gewalt (Traumen) oder durch verschiedene innere Ursachen (Stoffwechsel, Vorschädigung etc.) hervorgerufen werden. 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/32354393/The_Effect_of_an_Individualized_Fall_Prevention_Program_on_Fall_Risk_and_Falls_in_Older_People_A_Randomized_Controlled_Trial">The Effect of an Individualized Fall Prevention Program on Fall Risk and Falls in Older People: A Randomized, Controlled Trial</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/32354393" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div 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Tiedemann</a><script data-card-contents-for-user="62786691" type="text/json">{"id":62786691,"first_name":"Anne","last_name":"Tiedemann","domain_name":"independent","page_name":"TiedemannAnne","display_name":"Anne Tiedemann","profile_url":"https://independent.academia.edu/TiedemannAnne?f_ri=71469","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_32354393 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="32354393"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 32354393, container: ".js-paper-rank-work_32354393", }); });</script></li><li class="js-percentile-work_32354393 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x 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type="text/json">{"id":867,"name":"Perception","url":"https://www.academia.edu/Documents/in/Perception?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2506" rel="nofollow" href="https://www.academia.edu/Documents/in/Gerontology">Gerontology</a>, <script data-card-contents-for-ri="2506" type="text/json">{"id":2506,"name":"Gerontology","url":"https://www.academia.edu/Documents/in/Gerontology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="7462" rel="nofollow" href="https://www.academia.edu/Documents/in/Randomization">Randomization</a><script data-card-contents-for-ri="7462" type="text/json">{"id":7462,"name":"Randomization","url":"https://www.academia.edu/Documents/in/Randomization?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=32354393]'), work: {"id":32354393,"title":"The Effect of an 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Trial","url":"https://www.academia.edu/Documents/in/Randomized_Controlled_Trial?f_ri=71469"},{"id":561304,"name":"Lower limb","url":"https://www.academia.edu/Documents/in/Lower_limb?f_ri=71469"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=71469"},{"id":638048,"name":"Physical Exercise","url":"https://www.academia.edu/Documents/in/Physical_Exercise?f_ri=71469"},{"id":1305950,"name":"Postural Sway","url":"https://www.academia.edu/Documents/in/Postural_Sway?f_ri=71469"},{"id":1631043,"name":"Control Group","url":"https://www.academia.edu/Documents/in/Control_Group?f_ri=71469"},{"id":1937356,"name":"Risk Score","url":"https://www.academia.edu/Documents/in/Risk_Score?f_ri=71469"},{"id":2246011,"name":"Fall","url":"https://www.academia.edu/Documents/in/Fall?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_4312910" data-work_id="4312910" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/4312910/Myoglobin_as_a_polymerase_chain_reaction_PCR_inhibitor_A_limitation_for_PCR_from_skeletal_muscle_tissue_avoided_by_the_use_of_thermus_thermophilus_polymerase">Myoglobin as a polymerase chain reaction (PCR) inhibitor: A limitation for PCR from skeletal muscle tissue avoided by the use of thermus thermophilus polymerase</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Skeletal muscle tissue contains polymerase chain reaction (PCR) inhibitors that are coextracted by conventional nucleic acid extraction procedures. Myoglobin, a heme-containing molecule, was shown to act as a potent Thermus aquaticus DNA... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_4312910" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Skeletal muscle tissue contains polymerase chain reaction (PCR) inhibitors that are coextracted by conventional nucleic acid extraction procedures. Myoglobin, a heme-containing molecule, was shown to act as a potent Thermus aquaticus DNA polymerase inhibitor and is likely to be involved in muscle tissue-associated PCR inhibition. The use of Thermus thermophilus DNA polymerase avoids muscle tissue-associated PCR inhibition, and should be used in case of small amounts or instability of the targeted nucleic acid.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/4312910" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="088fb452144b00c8b664355790c2fb44" rel="nofollow" data-download="{"attachment_id":49948522,"asset_id":4312910,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49948522/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5249853" href="https://tunis.academia.edu/AliMohamed">Ali Mohamed</a><script data-card-contents-for-user="5249853" type="text/json">{"id":5249853,"first_name":"Ali","last_name":"Mohamed","domain_name":"tunis","page_name":"AliMohamed","display_name":"Ali Mohamed","profile_url":"https://tunis.academia.edu/AliMohamed?f_ri=71469","photo":"https://0.academia-photos.com/5249853/2310190/2696093/s65_ali.mohamed.jpg"}</script></span></span></li><li class="js-paper-rank-work_4312910 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="4312910"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 4312910, container: ".js-paper-rank-work_4312910", }); });</script></li><li class="js-percentile-work_4312910 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 4312910; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_4312910"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_4312910 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="4312910"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 4312910; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=4312910]").text(description); $(".js-view-count-work_4312910").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_4312910").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="4312910"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="4228" rel="nofollow" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71469" rel="nofollow" href="https://www.academia.edu/Documents/in/Muscle">Muscle</a>, <script data-card-contents-for-ri="71469" type="text/json">{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="118339" rel="nofollow" href="https://www.academia.edu/Documents/in/Polymerase_Chain_Reaction">Polymerase Chain Reaction</a>, <script data-card-contents-for-ri="118339" type="text/json">{"id":118339,"name":"Polymerase Chain Reaction","url":"https://www.academia.edu/Documents/in/Polymerase_Chain_Reaction?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="293824" rel="nofollow" href="https://www.academia.edu/Documents/in/Myoglobin">Myoglobin</a><script data-card-contents-for-ri="293824" type="text/json">{"id":293824,"name":"Myoglobin","url":"https://www.academia.edu/Documents/in/Myoglobin?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=4312910]'), work: {"id":4312910,"title":"Myoglobin as a polymerase chain reaction (PCR) inhibitor: A limitation for PCR from skeletal muscle tissue avoided by the use of thermus thermophilus polymerase","created_at":"2013-08-23T21:21:34.588-07:00","url":"https://www.academia.edu/4312910/Myoglobin_as_a_polymerase_chain_reaction_PCR_inhibitor_A_limitation_for_PCR_from_skeletal_muscle_tissue_avoided_by_the_use_of_thermus_thermophilus_polymerase?f_ri=71469","dom_id":"work_4312910","summary":"Skeletal muscle tissue contains polymerase chain reaction (PCR) inhibitors that are coextracted by conventional nucleic acid extraction procedures. Myoglobin, a heme-containing molecule, was shown to act as a potent Thermus aquaticus DNA polymerase inhibitor and is likely to be involved in muscle tissue-associated PCR inhibition. The use of Thermus thermophilus DNA polymerase avoids muscle tissue-associated PCR inhibition, and should be used in case of small amounts or instability of the targeted nucleic acid.","downloadable_attachments":[{"id":49948522,"asset_id":4312910,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5249853,"first_name":"Ali","last_name":"Mohamed","domain_name":"tunis","page_name":"AliMohamed","display_name":"Ali Mohamed","profile_url":"https://tunis.academia.edu/AliMohamed?f_ri=71469","photo":"https://0.academia-photos.com/5249853/2310190/2696093/s65_ali.mohamed.jpg"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=71469","nofollow":true},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469","nofollow":true},{"id":118339,"name":"Polymerase Chain Reaction","url":"https://www.academia.edu/Documents/in/Polymerase_Chain_Reaction?f_ri=71469","nofollow":true},{"id":293824,"name":"Myoglobin","url":"https://www.academia.edu/Documents/in/Myoglobin?f_ri=71469","nofollow":true},{"id":357849,"name":"Skeletal Muscle","url":"https://www.academia.edu/Documents/in/Skeletal_Muscle?f_ri=71469"},{"id":392828,"name":"Myocardium","url":"https://www.academia.edu/Documents/in/Myocardium?f_ri=71469"},{"id":2533047,"name":"fibroblasts","url":"https://www.academia.edu/Documents/in/fibroblasts?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27180490" data-work_id="27180490" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27180490/Wireless_Sensor_Devices_in_Sports_Performance">Wireless Sensor Devices in Sports Performance</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Sensor devices are an integral part of human movement analysis. The use of sensors in sports performance and injury prevention is extremely useful. Over the years wireless systems have become increasingly popular and the analysis of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27180490" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Sensor devices are an integral part of human movement analysis.  The use of sensors in sports performance and injury prevention is extremely useful.  Over the years wireless systems have become increasingly popular and the analysis of human movement has been therefore simplified.  Inertial measurement units are very popular in physical activity monitoring and have become readily available for consumers.  The use of more advanced sensors to measure electrical and mechanical muscle activity tend to be tethered devices, thus data collection on more complex movements is limited.  This paper looks at the need for wireless solutions to these sensors and the proposal for a multi-channel sensor which incorporates all the necessary sensors for complete human movement analysis.  Wireless systems have the advantage of allowing the participant or athlete to perform the movement in their ecologically valid environment while giving both reliable and accurate results to the practitioner.  In terms of human movement, to achieve accurate information about the position, kinematic and external forces of the segments of the body being studied, a single multi-channel sensor device is necessary.  The combination of sensors in one device can give accurate information on muscle activity, forces, directionality and acceleration.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27180490" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4dd2c9d9a49bb3d161ae2c0834ff5de9" rel="nofollow" data-download="{"attachment_id":47531667,"asset_id":27180490,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47531667/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26770441" href="https://limerick.academia.edu/R%C3%B3is%C3%ADnHoward">Róisín Howard</a><script data-card-contents-for-user="26770441" type="text/json">{"id":26770441,"first_name":"Róisín","last_name":"Howard","domain_name":"limerick","page_name":"RóisínHoward","display_name":"Róisín Howard","profile_url":"https://limerick.academia.edu/R%C3%B3is%C3%ADnHoward?f_ri=71469","photo":"https://0.academia-photos.com/26770441/9193401/10251093/s65_r_is_n.howard.jpg"}</script></span></span></li><li class="js-paper-rank-work_27180490 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="27180490"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 27180490, container: ".js-paper-rank-work_27180490", }); });</script></li><li class="js-percentile-work_27180490 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27180490; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_27180490"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_27180490 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="27180490"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27180490; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27180490]").text(description); $(".js-view-count-work_27180490").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27180490").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27180490"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4735" rel="nofollow" href="https://www.academia.edu/Documents/in/Sensor">Sensor</a>, <script data-card-contents-for-ri="4735" type="text/json">{"id":4735,"name":"Sensor","url":"https://www.academia.edu/Documents/in/Sensor?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="9043" rel="nofollow" href="https://www.academia.edu/Documents/in/Performance">Performance</a>, <script data-card-contents-for-ri="9043" type="text/json">{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="15125" rel="nofollow" href="https://www.academia.edu/Documents/in/Semiconductor_Devices">Semiconductor Devices</a>, <script data-card-contents-for-ri="15125" type="text/json">{"id":15125,"name":"Semiconductor Devices","url":"https://www.academia.edu/Documents/in/Semiconductor_Devices?f_ri=71469","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="49905" rel="nofollow" href="https://www.academia.edu/Documents/in/Sport">Sport</a><script data-card-contents-for-ri="49905" type="text/json">{"id":49905,"name":"Sport","url":"https://www.academia.edu/Documents/in/Sport?f_ri=71469","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27180490]'), work: {"id":27180490,"title":"Wireless Sensor Devices in Sports Performance","created_at":"2016-07-22T06:38:34.615-07:00","url":"https://www.academia.edu/27180490/Wireless_Sensor_Devices_in_Sports_Performance?f_ri=71469","dom_id":"work_27180490","summary":"Sensor devices are an integral part of human movement analysis. The use of sensors in sports performance and injury prevention is extremely useful. Over the years wireless systems have become increasingly popular and the analysis of human movement has been therefore simplified. Inertial measurement units are very popular in physical activity monitoring and have become readily available for consumers. The use of more advanced sensors to measure electrical and mechanical muscle activity tend to be tethered devices, thus data collection on more complex movements is limited. This paper looks at the need for wireless solutions to these sensors and the proposal for a multi-channel sensor which incorporates all the necessary sensors for complete human movement analysis. Wireless systems have the advantage of allowing the participant or athlete to perform the movement in their ecologically valid environment while giving both reliable and accurate results to the practitioner. In terms of human movement, to achieve accurate information about the position, kinematic and external forces of the segments of the body being studied, a single multi-channel sensor device is necessary. The combination of sensors in one device can give accurate information on muscle activity, forces, directionality and acceleration.","downloadable_attachments":[{"id":47531667,"asset_id":27180490,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":26770441,"first_name":"Róisín","last_name":"Howard","domain_name":"limerick","page_name":"RóisínHoward","display_name":"Róisín Howard","profile_url":"https://limerick.academia.edu/R%C3%B3is%C3%ADnHoward?f_ri=71469","photo":"https://0.academia-photos.com/26770441/9193401/10251093/s65_r_is_n.howard.jpg"}],"research_interests":[{"id":4735,"name":"Sensor","url":"https://www.academia.edu/Documents/in/Sensor?f_ri=71469","nofollow":true},{"id":9043,"name":"Performance","url":"https://www.academia.edu/Documents/in/Performance?f_ri=71469","nofollow":true},{"id":15125,"name":"Semiconductor Devices","url":"https://www.academia.edu/Documents/in/Semiconductor_Devices?f_ri=71469","nofollow":true},{"id":49905,"name":"Sport","url":"https://www.academia.edu/Documents/in/Sport?f_ri=71469","nofollow":true},{"id":65580,"name":"EMG","url":"https://www.academia.edu/Documents/in/EMG?f_ri=71469"},{"id":71469,"name":"Muscle","url":"https://www.academia.edu/Documents/in/Muscle?f_ri=71469"},{"id":141099,"name":"Speed","url":"https://www.academia.edu/Documents/in/Speed?f_ri=71469"},{"id":170918,"name":"Electromyography","url":"https://www.academia.edu/Documents/in/Electromyography?f_ri=71469"},{"id":329868,"name":"Gyroscope","url":"https://www.academia.edu/Documents/in/Gyroscope?f_ri=71469"},{"id":479186,"name":"Accelerometer","url":"https://www.academia.edu/Documents/in/Accelerometer?f_ri=71469"},{"id":1142765,"name":"Surface Electromyography","url":"https://www.academia.edu/Documents/in/Surface_Electromyography?f_ri=71469"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28672210" data-work_id="28672210" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28672210/Isokinetic_exercise_in_rehabilitation">Isokinetic exercise in rehabilitation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Since isokinetic equipment was first designed in the late 1960s, many investigations have focused on the agonist-antagonist relationships, left-right imbalances and so on, in order to present normative data for the assessment of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_28672210" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Since isokinetic equipment was first designed in the late 1960s, many investigations have focused on the agonist-antagonist relationships, left-right imbalances and so on, in order to present normative data for the assessment of musculoskeletal injuries. Furthermore, the isokinetic principle has been applied in rehabilitation to minimise rehabilitation time, because it is thought that it may give a close-to-optimal training stimulus to the musculoskeletal system. However, much research still needs to be carried out in this field, in order to determine which evaluation protocols are relevant, which training regimen is optimal, and which angular velocities should be used to assess and/or rehabilitate muscle strength.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28672210" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d8e780e5e63c07a1c3c38f16deef07c7" rel="nofollow" data-download="{"attachment_id":49054669,"asset_id":28672210,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49054669/download_file?st=MTc0MDE2MTYyOCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="137839" href="https://independent.academia.edu/Cabri">Jan Cabri</a><script data-card-contents-for-user="137839" type="text/json">{"id":137839,"first_name":"Jan","last_name":"Cabri","domain_name":"independent","page_name":"Cabri","display_name":"Jan Cabri","profile_url":"https://independent.academia.edu/Cabri?f_ri=71469","photo":"https://0.academia-photos.com/137839/36588/7168980/s65_jan.cabri.jpg"}</script></span></span></li><li class="js-paper-rank-work_28672210 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="28672210"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 28672210, container: ".js-paper-rank-work_28672210", }); 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