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first"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/neuroscience" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--52">Neuroscience (29)<span class="element-invisible"> Apply Neuroscience filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/behavioral" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--53">behavioral (5)<span class="element-invisible"> Apply behavioral filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/development" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--54">Development (3)<span class="element-invisible"> Apply Development filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/inflammation" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--55">Inflammation (2)<span class="element-invisible"> Apply Inflammation filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/metabolic" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--56">Metabolic (1)<span class="element-invisible"> Apply Metabolic filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/kidney" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--57">Kidney (1)<span class="element-invisible"> Apply Kidney filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/diabetes" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--58">diabetes (1)<span class="element-invisible"> Apply diabetes filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/nueroscience" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--59">Nueroscience (1)<span class="element-invisible"> Apply Nueroscience filter </span></a></li><li class="leaf last"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/researcharea/senescense" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--60">Senescense (1)<span class="element-invisible"> Apply Senescense filter </span></a></li></ul></div></div></div><div id="block-facetapi-4qghbqioaspbmlriwmxbgpyg084wdrpv" class="block block-facetapi clearfix"><h2 class="title">Species common</h2><div class="content"><div class="item-list"><ul class="facetapi-facetapi-checkbox-links facetapi-facet-im-field-species-common" id="facetapi-facet-apachesolrpublication-solr-server-block-im-field-species-common"><li class="leaf first"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/mouse" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--2">Mouse (1253)<span class="element-invisible"> Apply Mouse filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/human" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--3">Human (381)<span class="element-invisible"> Apply Human filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/rat" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--4">Rat (117)<span class="element-invisible"> Apply Rat filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/zebrafish" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--5">Zebrafish (61)<span class="element-invisible"> Apply Zebrafish filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/tbd" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--6">TBD (58)<span class="element-invisible"> Apply TBD filter </span></a></li><li class="leaf"><span class='inactive-link'><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay" rel="nofollow" class="facetapi-checkbox facetapi-active" id="facetapi-link--7">(-) <span class="element-invisible"> Remove Rats filter </span></a></span><span class='inactive-label'>Rats (35)</span></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/monkey" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--8">Monkey (15)<span class="element-invisible"> Apply Monkey filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/macaque" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--9">Macaque (13)<span class="element-invisible"> Apply Macaque filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/other" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--10">Other (8)<span class="element-invisible"> Apply Other filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/chicken" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--11">Chicken (8)<span class="element-invisible"> Apply Chicken filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/drosophila" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--12">Drosophila (7)<span class="element-invisible"> Apply Drosophila filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/hamster" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--13">Hamster (6)<span class="element-invisible"> Apply Hamster filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/pig" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--14">Pig (3)<span class="element-invisible"> Apply Pig filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/rainbow-trout" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--15">rainbow trout (3)<span class="element-invisible"> Apply rainbow trout filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/monkeys" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--16">Monkeys (3)<span class="element-invisible"> Apply Monkeys filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/dog" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--17">Dog (2)<span class="element-invisible"> Apply Dog filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/zebra-finch" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--18">Zebra Finch (2)<span class="element-invisible"> Apply Zebra Finch filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/mouse-humanized" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--19">Mouse (Humanized) (2)<span class="element-invisible"> Apply Mouse (Humanized) filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/macaques" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--20">Macaques (2)<span class="element-invisible"> Apply Macaques filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/mosquito" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--21">Mosquito (2)<span class="element-invisible"> Apply Mosquito filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/fly" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--22">Fly (2)<span class="element-invisible"> Apply Fly filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/trichoplax-adhaerens" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--23">Trichoplax adhaerens (2)<span class="element-invisible"> Apply Trichoplax adhaerens filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/mouse-embryo" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--24">Mouse embryo (2)<span class="element-invisible"> Apply Mouse embryo filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/bovine" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--25">Bovine (1)<span class="element-invisible"> Apply Bovine filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/hepatitis-b-virus" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--26">Hepatitis B virus (1)<span class="element-invisible"> Apply Hepatitis B virus filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/fruit-fly" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--27">Fruit Fly (1)<span class="element-invisible"> Apply Fruit Fly filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/sheep" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--28">Sheep (1)<span class="element-invisible"> Apply Sheep filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/japanese-medaka" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--29">Japanese medaka (1)<span class="element-invisible"> Apply Japanese medaka filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/guinea-pig" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--30">Guinea pig (1)<span class="element-invisible"> Apply Guinea pig filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/canine" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--31">Canine (1)<span class="element-invisible"> Apply Canine filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/salmon" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--32">Salmon (1)<span class="element-invisible"> Apply Salmon filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/honey-bee" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--33">honey bee (1)<span class="element-invisible"> Apply honey bee filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/chimpanzee" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--34">chimpanzee (1)<span class="element-invisible"> Apply chimpanzee filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/marmoset" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--35">Marmoset (1)<span class="element-invisible"> Apply Marmoset filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/fish" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--36">Fish (1)<span class="element-invisible"> Apply Fish filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/mouse-human-probes" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--37">Mouse (Human Probes) (1)<span class="element-invisible"> Apply Mouse (Human Probes) filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/bat" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--38">Bat (1)<span class="element-invisible"> Apply Bat filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/frog" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--39">Frog (1)<span class="element-invisible"> Apply Frog filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/ferret" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--40">Ferret (1)<span class="element-invisible"> Apply Ferret filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/locust" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--41">Locust (1)<span class="element-invisible"> Apply Locust filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/salamander" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--42">Salamander (1)<span class="element-invisible"> Apply Salamander filter </span></a></li><li class="leaf"><a href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats/speciescommon/mouse-0" rel="nofollow" class="facetapi-checkbox facetapi-inactive" id="facetapi-link--43">Mouse ? 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row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.science.org/doi/abs/10.1126/sciadv.abh2399"> Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism </a></div></div><div class="col-sm-2"><p>Science advances</p></div><div class="col-sm-2"><p>2021 Nov 19</p></div><div class="clear"></div><div class="col-sm-8"><p> Meinhardt, MW;Pfarr, S;Fouquet, G;Rohleder, C;Meinhardt, ML;Barroso-Flores, J;Hoffmann, R;Jeanblanc, J;Paul, E;Wagner, K;Hansson, AC;Köhr, G;Meier, N;von Bohlen Und Halbach, O;Bell, RL;Endepols, H;Neumaier, B;Schönig, K;Bartsch, D;Naassila, M;Spanagel, R;Sommer, WH; <br/> PMID: <a href="https://www.science.org/doi/abs/10.1126/sciadv.abh2399" target="_blank">34788104</a> | DOI: 10.1126/sciadv.abh2399</p></div><div class="clear"></div><div class="descp publication-abstract-read"> [Figure: see text].</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32315363"> Increased apelin receptor gene expression in the subfornical organ of spontaneously hypertensive rats </a></div></div><div class="col-sm-2"><p>PLoS One</p></div><div class="col-sm-2"><p>2020 Apr 21</p></div><div class="clear"></div><div class="col-sm-8"><p> Griffiths PR, Lolait SJ, Bijabhai A, O'Carroll-Lolait A, Paton JFR, O'Carroll AM <br/> PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/32315363" target="_blank">32315363</a> | DOI: 10.1371/journal.pone.0231844</p></div><div class="clear"></div><div class="descp publication-abstract-read"> The vascular organ of the lamina terminalis, subfornical organ (SFO), and area postrema comprise the sensory circumventricular organs (CVO) which are central structures that lie outside the blood brain barrier and are thought to provide an interface between peripherally circulating signals and the brain through their projections to central autonomic structures. The SFO expresses mRNA for the G protein-coupled apelin receptor (APJ, gene name aplnr) and exogenous microinjection of the neuropeptide apelin (apln) to the SFO elicits a depressor effect. Here we investigated the expression and cellular distribution of aplnr, apln and the recently described ligand apela (apela) in the CVOs and investigated whether differences in the levels of expression of apelinergic gene transcripts in these regions might underlie the chronic elevated blood pressure seen in hypertension. We carried out multiplex in situ hybridization histochemistry on CVO tissue sections from spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto (WKY) controls. Confocal immunofluorescent images indicated strong aplnr expression, with lower levels of apln and modest apela expression, in the CVOs of both WKY rats and SHRs, in both neurons and glia. The expression level of aplnr transcripts was increased in the SFO of SHRs compared to WKY rats. Our data may highlight a potential dysfunction in the communication between CVOs and downstream signalling pathways in SHRs, which may contribute to its different phenotype/s</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="http://dx.doi.org/10.1016/j.expneurol.2022.114030"> Cervical spinal hemisection alters phrenic motor neuron glutamatergic mRNA receptor expression </a></div></div><div class="col-sm-2"><p>Experimental Neurology</p></div><div class="col-sm-2"><p>2022 Mar 01</p></div><div class="clear"></div><div class="col-sm-8"><p> Rana, S;Zhan, W;Sieck, G;Mantilla, C; <br/> | DOI: 10.1016/j.expneurol.2022.114030</p></div><div class="clear"></div><div class="descp publication-abstract-read"> Upper cervical spinal cord injuries (SCI) disrupt descending inputs to phrenic motor neurons (PhMNs), impairing respiratory function. Unilateral spinal hemisection at C2 (C2SH) results in loss of ipsilateral rhythmic diaphragm muscle (DIAm) EMG activity associated with lower force behaviors accomplished by recruitment of smaller PhMNs that recovers over time in rats. Activity during higher force, non-ventilatory behaviors that recruit larger PhMNs is minimally impaired following C2SH. We previously showed neuroplasticity in glutamatergic receptor expression in PhMN post-C2SH with changes in NMDA receptor expression reflecting functional recovery. We hypothesize that C2SH-induced changes in glutamatergic receptor (AMPA and NMDA) mRNA expression in PhMNs vary with motor neuron size, with more pronounced changes in smaller PhMNs. Retrogradely-labelled PhMNs were classified in tertiles according to somal surface area and mRNA expression was measured using single-cell, multiplex fluorescence in situ hybridization. Ipsilateral to C2SH, a pronounced reduction in NMDA mRNA expression in PhMNs was evident at 3 days post-injury with similar impact on PhMNs in the lower size tertile (~68% reduction) and upper tertile (~60%); by 21DSH, there was near complete restoration of NMDA receptor mRNA expression across all PhMNs. There were no changes in NMDA mRNA expression contralateral to C2SH. There were no changes in AMPA mRNA expression at PhMNs on either side of the spinal cord or at any time-point post-C2SH. In summary, following C2SH there is ipsilateral reduction in PhMN NMDA mRNA expression at 3DSH that is not limited to smaller PhMN recruited in the generation of lower force ventilatory behaviors. The recovery of NMDA mRNA expression by 21DSH is consistent with evidence of spontaneous recovery of ipsilateral DIAm activity at this timepoint. These findings suggest a possible role for NMDA receptor mediated glutamatergic signaling in mechanisms supporting postsynaptic neuroplasticity at the PhMN pool and recovery of DIAm activity after cervical SCI.</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name">Resolving the cellular specificity of TSPO imaging in a rat model of peripherally-induced neuroinflammation</div></div><div class="col-sm-2"><p>Brain, behavior, and immunity</p></div><div class="col-sm-2"><p>2021 May 27</p></div><div class="clear"></div><div class="col-sm-8"><p> Vicente-Rodríguez, M;Singh, N;Turkheimer, F;Peris-Yague, A;Randall, K;Veronese, M;Simmons, C;Karim Haji-Dheere, A;Bordoloi, J;Sander, K;Awais, RO;Årstad, E;Consortium, N;Cash, D;Parker, CA; <br/> PMID: 34052363 | DOI: 10.1016/j.bbi.2021.05.025</p></div><div class="clear"></div><div class="descp publication-abstract-read"> the increased expression of 18kDa Translocator protein (TSPO) is one of the few available biomarkers of neuroinflammation that can be assessed in humans in vivo by positron emission tomography (PET). TSPO PET imaging of the central nervous system (CNS) has been widely undertaken, but to date no clear consensus has been reached about its utility in brain disorders. One reason for this could be because the interpretation of TSPO PET signal remains challenging, given the cellular heterogeneity and ubiquity of TSPO in the brain. the aim of the current study was to ascertain if TSPO PET imaging can be used to detect neuroinflammation induced by a peripheral treatment with endotoxin lipopolysaccharide (LPS) in a rat model (ip LPS), and investigate the origin of TSPO signal changes in terms of their cellular sources and regional distribution. An initial pilot study utilising both [18F]DPA-714 and [11C]PK11195 demonstrated [18F]DPA-714 to exhibit a significantly higher lesion-related signal in the intracerebral LPS rat model (ic LPS) than [11C]PK11195. Subsequently, [18F]DPA-714 was selected for use in the ip LPS study. twenty-four hours after ip LPS, there was an increased uptake of [18F]DPA-714 across the whole brain. Further analyses of regions of interest, using immunohistochemistry and RNAscope Multiplex fluorescence V2 in situ hybridization technology, showed TSPO expression in microglia, monocyte derived-macrophages, astrocytes, neurons and endothelial cells. The expression of TSPO was significantly increased after ip LPS in a region-dependent manner; with microglia, monocyte-derived macrophages and astrocytes in the substantia nigra, in contrast to the hippocampus where TSPO was mostly confined to microglia and astrocytes. in summary, our data demonstrate the robust detection of peripherally-induced neuroinflammation in the CNS utilizing the TSPO radioligand [18F]DPA-714, and importantly, confirm that the TSPO signal increase arises mostly from a combination of microglia, astrocytes and monocyte-derived macrophages.</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.sciencedirect.com/science/article/pii/S2666166722000405"> Identification and three-dimensional reconstruction of oxytocin receptor expressing astrocytes in the rat and mouse brain </a></div></div><div class="col-sm-2"><p>STAR protocols</p></div><div class="col-sm-2"><p>2022 Mar 18</p></div><div class="clear"></div><div class="col-sm-8"><p> Althammer, F;Krause, EG;de Kloet, AD;Smith, J;Grinevich, V;Charlet, A;Stern, JE; <br/> PMID: <a href="https://www.sciencedirect.com/science/article/pii/S2666166722000405" target="_blank">35199030</a> | DOI: 10.1016/j.xpro.2022.101160</p></div><div class="clear"></div><div class="descp publication-abstract-read"> Here, we present a step-by-step protocol for three-dimensional reconstruction of astrocyte morphology, applied to the central amygdala oxytocin receptor-expressing astrocytes. This includes RNAse-free perfusion, combination of RNAscope and immunohistochemistry, and confocal imaging. This protocol provides detailed information about tissue handling and a comprehensive description of the RNAScope technique to label rat and mouse oxytocin receptor mRNA. We also describe three-dimensional reconstruction that allows the assessment of more than 70 different cellular parameters, powerful for studying astrocyte morphology and astrocyte-astrocyte interactions. For complete details on the use and execution of this protocol, please refer to Wahis et al. (2021) and Althammer et al. (2020).</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32152264"> Dorsal vagal complex and hypothalamic glia differentially respond to leptin and energy balance dysregulation </a></div></div><div class="col-sm-2"><p>Transl Psychiatry</p></div><div class="col-sm-2"><p>2020 Mar 09</p></div><div class="clear"></div><div class="col-sm-8"><p> Stein LM, Lhamo R, Cao A, Workinger J, Tinsley I, Doyle RP, Grill HJ, Hermann GE, Rogers RC, Hayes MR <br/> PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/32152264" target="_blank">32152264</a> | DOI: 10.1038/s41398-020-0767-0</p></div><div class="clear"></div><div class="descp publication-abstract-read"> Previous studies identify a role for hypothalamic glia in energy balance regulation; however, a narrow hypothalamic focus provides an incomplete understanding of how glia throughout the brain respond to and regulate energy homeostasis. We examined the responses of glia in the dorsal vagal complex (DVC) to the adipokine leptin and high fat diet-induced obesity. DVC astrocytes functionally express the leptin receptor; in vivo pharmacological studies suggest that DVC astrocytes partly mediate the anorectic effects of leptin in lean but not diet-induced obese rats. Ex vivo calcium imaging indicated that these changes were related to a lower proportion of leptin-responsive cells in the DVC of obese versus lean animals. Finally, we investigated DVC microglia and astroglia responses to leptin and energy balance dysregulation in vivo: obesity decreased DVC astrogliosis, whereas the absence of leptin signaling in Zucker rats was associated with extensive astrogliosis in the DVC and decreased hypothalamic micro- and astrogliosis. These data uncover a novel functional heterogeneity of astrocytes in different brain nuclei of relevance to leptin signaling and energy balance regulation</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32059750"> Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by?-synuclein </a></div></div><div class="col-sm-2"><p>Acta Neuropathol Commun.</p></div><div class="col-sm-2"><p>2020 Feb 14</p></div><div class="clear"></div><div class="col-sm-8"><p> McKinnon C, De Snoo ML, Gondard E, Neudorfer C, Chau H, Ngana SG, O'Hara DM, Brotchie JM, Koprich JB, Lozano AM, Kalia LV, Kalia SK <br/> PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/32059750" target="_blank">32059750</a> | DOI: 10.1186/s40478-020-0894-0</p></div><div class="clear"></div><div class="descp publication-abstract-read"> Parkinson's disease is a progressive neurodegenerative disorder characterised by the accumulation of misfolded ?-synuclein in selected brain regions, including the substantia nigra pars compacta (SNpc), where marked loss of dopaminergic neurons is also observed. Yet, the relationship between misfolded ?-synuclein and neurotoxicity currently remains unclear. As the principal route for degradation of misfolded proteins in mammalian cells, the ubiquitin-proteasome system (UPS) is critical for maintenance of cellular proteostasis. Misfolded ?-synuclein impairs UPS function and contributes to neuronal death in vitro. Here, we examine its effects in vivo using adeno-associated viruses to co-express A53T ?-synuclein and the ubiquitinated reporter protein UbG76V-GFP in rat SNpc. We found that ?-synuclein over-expression leads to early-onset catalytic impairment of the 26S proteasome with associated UPS dysfunction, preceding the onset of behavioural deficits and dopaminergic neurodegeneration. UPS failure in dopaminergic neurons was also associated with selective accumulation of ?-synuclein phosphorylated at the serine 129 residue, which has previously been linked to increased neurotoxicity. Our study highlights a role for ?-synuclein in disturbing proteostasis which may contribute to neurodegeneration in vivo</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/32054836"> Enhancing neuronal chloride extrusion rescues?2/?3 GABAA-mediated analgesia in neuropathic pain </a></div></div><div class="col-sm-2"><p>Nat Commun</p></div><div class="col-sm-2"><p>2020 Feb 13</p></div><div class="clear"></div><div class="col-sm-8"><p> Lorenzo LE, Godin AG, Ferrini F, Bachand K, Plasencia-Fernandez I, Labrecque S, Girard A, Boudreau D, Kianicka I, Gagnon M, Doyon N, Ribeiro-da-Silva A, De Koninck Y <br/> PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/32054836" target="_blank">32054836</a> | DOI: 10.1038/s41467-019-14154-6</p></div><div class="clear"></div><div class="descp publication-abstract-read"> Spinal disinhibition has been hypothesized to underlie pain hypersensitivity in neuropathic pain. Apparently contradictory mechanisms have been reported, raising questions on the best target to produce analgesia. Here, we show that nerve injury is associated with a reduction in the number of inhibitory synapses in the spinal dorsal horn. Paradoxically, this is accompanied by a BDNF-TrkB-mediated upregulation of synaptic GABAARs and by an ?1-to-?2GABAAR subunit switch, providing a mechanistic rationale for the analgesic action of the ?2,3GABAAR benzodiazepine-site ligand L838,417 after nerve injury. Yet, we demonstrate that impaired Cl- extrusion underlies the failure of L838,417 to induce analgesia at high doses due to a resulting collapse in Cl- gradient, dramatically limiting the benzodiazepine therapeutic window. In turn, enhancing KCC2 activity not only potentiated L838,417-induced analgesia, it rescued its analgesic potential at high doses, revealing a novel strategy for analgesia in pathological pain, by combined targeting of the appropriate GABAAR-subtypes and restoring Cl- homeostasis</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/31999650"> GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents </a></div></div><div class="col-sm-2"><p>J Clin Invest.</p></div><div class="col-sm-2"><p>2020 Jan 30</p></div><div class="clear"></div><div class="col-sm-8"><p> Yosten GL, Harada CM, Haddock CJ, Giancotti LA, Kolar GR, Patel R, Guo C, Chen Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D. <br/> PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31999650" target="_blank">31999650</a> | DOI: 10.1172/JCI133270</p></div><div class="clear"></div><div class="descp publication-abstract-read"> Treating neuropathic pain is challenging and novel non-opioid based medicines are needed. Using unbiased receptomics, transcriptomic analyses, immunofluorescence and in situ hybridization, we found the expression of the orphan GPCR (oGPCR) Gpr160 and GPR160 increased in the rodent dorsal horn of the spinal cord (DH-SC) following traumatic nerve injury. Genetic and immunopharmacological approaches demonstrated that GPR160 inhibition in the spinal cord prevented and reversed neuropathic pain in male and female rodents without altering normal pain response. GPR160 inhibition in the spinal cord attenuated sensory processing in the thalamus, a key relay in the sensory discriminative pathways of pain. We also identified cocaine- and amphetamine-regulated transcript peptide (CARTp) as a GPR160 ligand. Inhibiting endogenous CARTp signaling in spinal cord attenuated neuropathic pain, whereas exogenous intrathecal (i.th.) CARTp evoked painful hypersensitivity through GPR160-dependent ERK and cAMP response element-binding protein (CREB). Our findings de-orphanize GPR160, identify it as a determinant of neuropathic pain and potential therapeutic target, and provide insights to its signaling pathways. CARTp is involved in many diseases including depression, reward and addiction, de-orphanization of GPR160 is a major step forward understanding the role of CARTp signaling in health and disease</div></div><div class="row row-static row-publication"><div class="col-sm-8"><div class="pro-title name"> <a href="https://www.ncbi.nlm.nih.gov/pubmed/31949158"> Microglial activation increases cocaine self-administration following adolescent nicotine exposure </a></div></div><div class="col-sm-2"><p>Nat Commun</p></div><div class="col-sm-2"><p>2020 Jan 16</p></div><div class="clear"></div><div class="col-sm-8"><p> Linker KE, Elabd MG, Tawadrous P, Cano M, Green KN, Wood MA, Leslie FM <br/> PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/31949158" target="_blank">31949158</a> | DOI: 10.1038/s41467-019-14173-3</p></div><div class="clear"></div><div class="descp publication-abstract-read"> With the rise of e-cigarette use, teen nicotine exposure is becoming more widespread. Findings from clinical and preclinical studies show that the adolescent brain is particularly sensitive to nicotine. Animal studies have demonstrated that adolescent nicotine exposure increases reinforcement for cocaine and other drugs. However, the mechanisms that underlie these behaviors are poorly understood. Here, we report reactive microglia are critical regulators of nicotine-induced increases in adolescent cocaine self-administration. Nicotine has dichotomous, age-dependent effects on microglial morphology and immune transcript profiles. A multistep signaling mechanism involving D2 receptors and CX3CL1 mediates nicotine-induced increases in cocaine self-administration and microglial activation. Moreover, nicotine depletes presynaptic markers in a manner that is microglia-, D2- and CX3CL1-dependent. Taken together, we demonstrate that adolescent microglia are uniquely susceptible to perturbations by nicotine, necessary for nicotine-induced increases in cocaine-seeking, and that D2 receptors and CX3CL1 play a mechanistic role in these phenomena</div></div></div><h2 class="element-invisible">Pages</h2><div class="item-list"><ul class="pager"><li class="pager-current first">1</li><li class="pager-item"><a title="Go to page 2" href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats?page=1">2</a></li><li class="pager-item"><a title="Go to page 3" href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats?page=2">3</a></li><li class="pager-item"><a title="Go to page 4" href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats?page=3">4</a></li><li class="pager-next"><a title="Go to next page" href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats?page=1">next ›</a></li><li class="pager-last last"><a title="Go to last page" href="/science/scientific-resources/publications/multiplex/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-multiplex-fluorescent-assay/product/rnascope%3Csup%3E%C2%AE%3C/sup%3E-ls-multiplex-assay/speciescommon/rats?page=3">last »</a></li></ul></div><div id="probes-info-table" class="search-probes-info"><div class="ecom-feature-container"><div class="help-ticket-close ">X</div><div class="ecom-feature-content"><div class="probes-help-text classification"><table cellspacing="0" border="0"><colgroup span="3" width="85"></colgroup><thead><tr><th></th><th>Description</th></tr></thead><tbody><tr><td>sense<br><strong>Example:</strong> Hs-LAG3-sense</td><td>Standard probes for RNA detection are in antisense. Sense probe is reverse complent to the corresponding antisense probe.</td></tr><tr><td>Intron#<br><strong>Example:</strong> Mm-Htt-intron2</td><td>Probe targets the indicated intron in the target gene, commonly used for pre-mRNA detection</td></tr><tr><td>Pool/Pan<br><strong>Example:</strong> Hs-CD3-pool (Hs-CD3D, Hs-CD3E, Hs-CD3G)</td><td>A mixture of multiple probe sets targeting multiple genes or transcripts</td></tr><tr><td>No-XSp<br><strong>Example:</strong> Hs-PDGFB-No-XMm</td><td>Does not cross detect with the species (Sp)</td></tr><tr><td>XSp<br><strong>Example:</strong> Rn-Pde9a-XMm</td><td>designed to cross detect with the species (Sp)</td></tr><tr><td>O#<br><strong>Example:</strong> Mm-Islr-O1</td><td>Alternative design targeting different regions of the same transcript or isoforms</td></tr><tr><td>CDS<br><strong>Example:</strong> Hs-SLC31A-CDS</td><td>Probe targets the protein-coding sequence only</td></tr><tr><td>EnEm</td><td>Probe targets exons n and m</td></tr><tr><td>En-Em</td><td>Probe targets region from exon n to exon m</td></tr><tr><td colspan=3 style="text-align: center; font-weight: bold;">Retired Nomenclature</td></tr><tr><td>tvn<br><strong>Example:</strong> Hs-LEPR-tv1</td><td>Designed to target transcript variant n</td></tr><tr><td>ORF<br><strong>Example:</strong> Hs-ACVRL1-ORF</td><td>Probe targets open reading frame</td></tr><tr><td>UTR<br><strong>Example:</strong> Hs-HTT-UTR-C3</td><td>Probe targets the untranslated region (non-protein-coding region) only</td></tr><tr><td>5UTR<br><strong>Example:</strong> Hs-GNRHR-5UTR</td><td>Probe targets the 5' untranslated region only</td></tr><tr><td>3UTR<br><strong>Example:</strong> Rn-Npy1r-3UTR</td><td>Probe targets the 3' untranslated region only</td></tr><tr><td>Pan<br><strong>Example:</strong> Pool</td><td>A mixture of multiple probe sets targeting multiple genes or transcripts</td></tr></tbody></table></div></div></div></div> <script type="text/javascript"> jQuery(document).ready(function($) { $(".probes-info.gene-tooltip").click(function(e) { e.preventDefault(); e.stopPropagation(); }); $('.probes-info.gene-tooltip').on('click', function(){ $('.search-probes-info').addClass("active"); 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.embeddedServiceLiveAgentStateChatHeader:not(.alert) .message { margin: 0; width: auto; } span#helpButtonSpan { padding: 0 50px 0 30px; } .embeddedServiceLiveAgentStateChatHeaderOption .optionName { color: #ffffff; } /* hide the URL capture field and label */ #OmniURL__c { display: none; } .prechatUI .fieldList li:nth-child(6) label { display: none; } /* Added 10px margin-top to center header text */ .headerText { margin-top: 10px; } </style> <!-- Automated_Invitation CSS --> <style type='text/css'> #snapins_invite { position: fixed !important; background-color: #FFFFFF; font-family: "Arial", sans-serif; overflow: visible; border-radius: 8px; visibility: hidden; } .embeddedServiceInvitation { background-color: transparent; max-width: 290px; max-height: 210px; -webkit-box-shadow: 0 7px 12px rgba(0, 0, 0, 0.28); -moz-box-shadow: 0 7px 12px rgba(0, 0, 0, 0.28); box-shadow: 0 7px 12px rgba(0, 0, 0, 0.28); } @media only screen and (min-width: 48em) { /*mobile*/ .embeddedServiceInvitation { max-width: 332px; max-height: 210px; } } .embeddedServiceInvitation>.embeddedServiceInvitationHeader { width: inherit; height: 48px; line-height: auto; padding: 10px; color: #FFFFFF; background-color: #005f9e; overflow: initial; display: flex; justify-content: space-between; align-items: stretch; border-top-left-radius: 8px; border-top-right-radius: 8px; } .embeddedServiceInvitationHeader #embeddedServiceAvatar { width: 32px; height: 32px; border-radius: 50%; } .embeddedServiceInvitationHeader .embeddedServiceTitleText { font-size: 18px; color: #FFFFFF; overflow: hidden; word-wrap: normal; white-space: nowrap; text-overflow: ellipsis; align-self: stretch; flex-grow: 1; max-width: 100%; margin: 0 12px; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon { background-image: none; border: none; border-radius: 3px; cursor: pointer; position: relative; bottom: 3%; background-color: transparent; width: 32px; height: 32px; font-size: 23px; color: #FFFFFF; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon:focus { outline: none; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon:focus::before { content: " "; position: absolute; top: 11%; left: 7%; width: 85%; height: 85%; background-color: rgba(255, 255, 255, 0.2); border-radius: 4px; pointer-events: none; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon:active, .embeddedServiceCloseIcon:hover { background-color: #FFFFFF; color: rgba(0, 0, 0, 0.7); opacity: 0.7; } .embeddedServiceInvitation>.embeddedServiceInvitationBody { background-color: #FFFFFF; max-height: 110px; min-width: 260px; margin: 0 8px; font-size: 14px; line-height: 20px; overflow: auto; } .embeddedServiceInvitationBody p { color: #333333; padding: 8px; margin: 12px 0; } .embeddedServiceInvitation>.embeddedServiceInvitationFooter { width: inherit; color: #FFFFFF; text-align: right; background-color: #FFFFFF; padding: 10px; max-height: none; border-bottom-left-radius: 8px; border-bottom-right-radius: 8px; margin-bottom: 10px; } .embeddedServiceInvitationFooter>.embeddedServiceActionButton { font-size: 14px; max-height: 40px; border: none; border-radius: 4px; padding: 10px; margin: 4px; text-align: center; text-decoration: none; display: inline-block; cursor: pointer; } .embeddedServiceInvitationFooter>#acceptInvite { background-image: none; background-color: #005f9e; color: #FFFFFF; } .embeddedServiceInvitationFooter>#rejectInvite { background-image: none; background-color: #FFFFFF; color: #005f9e; } </style> <!-- ...END --> <!-- Start of Invitations --> <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" aria-describedby="snapins_bodytext"> <img id="embeddedServiceAvatar"></img> <span class="embeddedServiceTitleText" id="snapins_titletext">Need help?</span> <button type="button" id="closeInvite" class="embeddedServiceCloseIcon" aria-label="Exit invitation">&times;</button> </div> <div class="embeddedServiceInvitationBody"> <p id="snapins_bodytext">How can we help you?</p> </div> <div class="embeddedServiceInvitationFooter" aria-describedby="snapins_bodytext"> <button type="button" class="embeddedServiceActionButton" id="rejectInvite">Close</button> <button type="button" class="embeddedServiceActionButton" id="acceptInvite">Start Chat</button> </div> </div> <style type='text/css'> #snapins_invite { background-color: #FFFFFF; font-family: "Arial", sans-serif; overflow: visible; border-radius: 8px; visibility: hidden; } .embeddedServiceInvitation { background-color: transparent; max-width: 290px; max-height: 210px; -webkit-box-shadow: 0 7px 12px rgba(0,0,0,0.28); -moz-box-shadow: 0 7px 12px rgba(0,0,0,0.28); box-shadow: 0 7px 12px rgba(0,0,0,0.28); } @media only screen and (min-width: 48em) { /*mobile*/ .embeddedServiceInvitation { max-width: 332px; max-height: 210px; } } .embeddedServiceInvitation > .embeddedServiceInvitationHeader { width: inherit; height: 32px; line-height: 32px; padding: 10px; color: #FFFFFF; background-color: #222222; overflow: initial; display: flex; justify-content: space-between; align-items: stretch; border-top-left-radius: 8px; border-top-right-radius: 8px; } .embeddedServiceInvitationHeader #embeddedServiceAvatar { width: 32px; height: 32px; border-radius: 50%; } .embeddedServiceInvitationHeader .embeddedServiceTitleText { font-size: 18px; color: #FFFFFF; overflow: hidden; word-wrap: normal; white-space: nowrap; text-overflow: ellipsis; align-self: stretch; flex-grow: 1; max-width: 100%; margin: 0 12px; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon { border: none; border-radius: 3px; cursor: pointer; position: relative; bottom: 3%; background-color: transparent; width: 32px; height: 32px; font-size: 23px; color: #FFFFFF; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon:focus { outline: none; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon:focus::before { content: " "; position: absolute; top: 11%; left: 7%; width: 85%; height: 85%; background-color: rgba(255, 255, 255, 0.2); border-radius: 4px; pointer-events: none; } .embeddedServiceInvitationHeader .embeddedServiceCloseIcon:active, .embeddedServiceCloseIcon:hover { background-color: #FFFFFF; color: rgba(0,0,0,0.7); opacity: 0.7; } .embeddedServiceInvitation > .embeddedServiceInvitationBody { background-color: #FFFFFF; max-height: 110px; min-width: 260px; margin: 0 8px; font-size: 14px; line-height: 20px; overflow: auto; } .embeddedServiceInvitationBody p { color: #333333; padding: 8px; margin: 12px 0; } .embeddedServiceInvitation > .embeddedServiceInvitationFooter { width: inherit; color: #FFFFFF; text-align: right; background-color: #FFFFFF; padding: 10px; max-height: 50px; border-bottom-left-radius: 8px; border-bottom-right-radius: 8px; } .embeddedServiceInvitationFooter > .embeddedServiceActionButton { font-size: 14px; max-height: 40px; border: none; border-radius: 4px; padding: 10px; margin: 4px; text-align: center; text-decoration: none; display: inline-block; cursor: pointer; } .embeddedServiceInvitationFooter > #acceptInvite { background-color: #005290; color: #FFFFFF; } .embeddedServiceInvitationFooter > #rejectInvite { background-color: #FFFFFF; color: #005290; } </style> <!-- doFind, doCreate and isExactMatch example for a Contact: Find a contact whose Email exactly matches the value provided by the customer in the form If there's no match, then create a Contact record and set it's First Name, Last Name, Email, and Phone to the values provided by the customer --> <!-- <input type="hidden" name="liveagent.prechat.findorcreate.map.doFind:Contact" value="Email,true" /> <input type="hidden" name="liveagent.prechat.findorcreate.map.isExactMatch:Contact" value="Email,true" /> <input type="hidden" name="liveagent.prechat.findorcreate.map.doCreate:Contact" value="LastName,true;FirstName,true;Email,true" />--> <input type="hidden" name="liveagent.prechat.findorcreate.map.doFind:Contact" value="LastName,true;FirstName,true;Email,true" /> <input type="hidden" name="liveagent.prechat.findorcreate.map.isExactMatch:Contact" value="LastName,true;FirstName,true;Email,true" /> <input type="hidden" name="liveagent.prechat.findorcreate.map.doCreate:Contact" value="LastName,true;FirstName,true;Email,true" /> <script type='text/javascript'> (function() { document.getElementById('closeInvite').onclick = function() { embedded_svc.inviteAPI.inviteButton.rejectInvite(); }; document.getElementById('rejectInvite').onclick = function() { embedded_svc.inviteAPI.inviteButton.rejectInvite(); }; // use this API call to reject invitations document.getElementById('acceptInvite').onclick = function() { embedded_svc.liveAgentAPI.startChat({ directToButtonRouting: { buttonId: "5733t000000cVk9" }, extraPrechatInfo: [], extraPrechatFormDetails: [] }); }; // use this API call to start chat from invitations document.addEventListener('keyup', function(event) { if (event.keyCode == 27) { embedded_svc.inviteAPI.inviteButton.rejectInvite(); }}) })(); </script> <!-- End of Invitations --> <script type='text/javascript' src='https://service.force.com/embeddedservice/5.0/esw.min.js'></script> <script type='text/javascript'> var initESW = function(gslbBaseURL) { embedded_svc.settings.displayHelpButton = true; //Or false embedded_svc.settings.language = ''; //For example, enter 'en' or 'en-US' embedded_svc.settings.defaultMinimizedText = 'Chat now'; //(Defaults to Chat with an Expert) embedded_svc.settings.disabledMinimizedText = 'Leave a message'; //(Defaults to Agent Offline) embedded_svc.settings.autoOpenPostChat = true; //embedded_svc.settings.loadingText = ''; //(Defaults to Loading) //embedded_svc.settings.storageDomain = 'yourdomain.com'; //(Sets the domain for your deployment so that visitors can navigate subdomains during a chat session) // Settings for Chat embedded_svc.settings.directToButtonRouting = function (prechatFormData) { if (prechatFormData[4].value === "Technical Service") return "5733t000000XZAM"; if (prechatFormData[4].value === "Customer Care") return "5733t000000XZAH"; }; embedded_svc.settings.prepopulatedPrechatFields = { OmniURL__c: window.location.href, ChooseaDepartment__c: 'Technical Service' }; //Sets the auto-population of pre-chat form fields embedded_svc.settings.extraPrechatFormDetails = [{ "label":"Source Domain", "value":window.location.href, "transcriptFields":[ "Source_Domain__c" ], "displayToAgent":true }]; //embedded_svc.settings.fallbackRouting = []; //An array of button IDs, user IDs, or userId_buttonId embedded_svc.settings.offlineSupportMinimizedText = 'Leave a message'; //(Defaults to Contact Us) embedded_svc.settings.enabledFeatures = ['LiveAgent']; embedded_svc.settings.entryFeature = 'LiveAgent'; embedded_svc.init( 'https://biotechne.my.salesforce.com', 'https://biotechne.my.salesforce-sites.com/LiveAgent', gslbBaseURL, '00D500000006gkl', 'ACD_Chat_Automated', { baseLiveAgentContentURL: 'https://c.la1-c1-ia5.salesforceliveagent.com/content', deploymentId: '572380000004CqL', buttonId: '5733t000000cVk9', baseLiveAgentURL: 'https://d.la1-c1-ia5.salesforceliveagent.com/chat', eswLiveAgentDevName: 'EmbeddedServiceLiveAgent_Parent04I3t000000Y7zbEAC_175bb741b99', isOfflineSupportEnabled: true } ); }; if (!window.embedded_svc) { var s = document.createElement('script'); s.setAttribute('src', 'https://biotechne.my.salesforce.com/embeddedservice/5.0/esw.min.js'); s.onload = function() { initESW(null); }; document.body.appendChild(s); } else { initESW('https://service.force.com'); } </script> <script src="//rum-static.pingdom.net/pa-5c133f6e1872b50016000024.js" async></script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"NRJS-dd6144c4de227d09eb4","applicationID":"1022125825","transactionName":"YFxbZkpUXBYEVkYNWVkWbEBRGlsLAVBKSkZfSQ==","queueTime":0,"applicationTime":414,"atts":"TBtYEAJOTxg=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>

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