CINXE.COM

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data-form="pathways_il-21_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-21 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-27_p28_il-30_signaling_pathways" action="/pathways/il-27-p28il-30-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-27-p28il-30-signaling-pathways" class="pathway_link" data-form="pathways_il-27_p28_il-30_signaling_pathways"> IL-27 p28/IL-30 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-31_signaling_pathways" action="/pathways/il-31-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-31-signaling-pathways" class="pathway_link" data-form="pathways_il-31_signaling_pathways"> IL-31 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-4_signaling_pathways" action="/pathways/il4-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il4-signaling-pathways" class="pathway_link" data-form="pathways_il-4_signaling_pathways"> IL-4 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-4_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-4-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-4-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-4_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-4 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-6_signaling_pathways" action="/pathways/il-6-family-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il-6-family-signaling-pathways" class="pathway_link" data-form="pathways_il-6_signaling_pathways"> IL-6 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-7_signaling_pathways" action="/pathways/il7-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il7-signaling-pathways" class="pathway_link" data-form="pathways_il-7_signaling_pathways"> IL-7 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-7_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-7-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-7-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-7_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-7 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-9_signaling_pathways" action="/pathways/il9-signaling-pathways" method="post"> <li class=""> <a href="/pathways/il9-signaling-pathways" class="pathway_link" data-form="pathways_il-9_signaling_pathways"> IL-9 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_il-9_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types" action="/pathways/il-9-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" method="post"> <li class=""> <a href="/pathways/il-9-signaling-pathways-their-primary-biological-effects-in-different-immune-cell-types" class="pathway_link" data-form="pathways_il-9_signaling_pathways_and_their_primary_biological_effects_in_different_immune_cell_types"> IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_inflammasome_activation_pathways" action="/pathways/inflammasome-activation-pathways" method="post"> <li class=""> <a href="/pathways/inflammasome-activation-pathways" class="pathway_link" data-form="pathways_inflammasome_activation_pathways"> Inflammasome Activation Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_innate_lymphoid_cell_differentiation_pathways" action="/pathways/innate-lymphoid-cell-differentiation-pathways" method="post"> <li class=""> <a href="/pathways/innate-lymphoid-cell-differentiation-pathways" class="pathway_link" data-form="pathways_innate_lymphoid_cell_differentiation_pathways"> Innate Lymphoid Cell Differentiation Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_lif_signaling_pathways" action="/pathways/lif-signaling-pathways" method="post"> <li class=""> <a href="/pathways/lif-signaling-pathways" class="pathway_link" data-form="pathways_lif_signaling_pathways"> LIF Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mdsc-mediated_mechanisms_of_immunosuppression" action="/pathways/mdsc-mediated-mechanisms-of-immunosuppression" method="post"> <li class=""> <a href="/pathways/mdsc-mediated-mechanisms-of-immunosuppression" class="pathway_link" data-form="pathways_mdsc-mediated_mechanisms_of_immunosuppression"> MDSC-Mediated Mechanisms of Immunosuppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mechanisms_of_regulatory_t_cell-mediated_suppression" action="/pathways/mechanisms-of-regulatory-t-cell-mediated-suppression" method="post"> <li class=""> <a href="/pathways/mechanisms-of-regulatory-t-cell-mediated-suppression" class="pathway_link" data-form="pathways_mechanisms_of_regulatory_t_cell-mediated_suppression"> Mechanisms of Regulatory T Cell-Mediated Suppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mechanisms_of_tumor-associated_macrophage_tam-mediated_immunosuppression" action="/pathways/tumor-associated-macrophage-tam" method="post"> <li class=""> <a href="/pathways/tumor-associated-macrophage-tam" class="pathway_link" data-form="pathways_mechanisms_of_tumor-associated_macrophage_tam-mediated_immunosuppression"> Mechanisms of Tumor-Associated Macrophage TAM-Mediated Immunosuppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_mechanisms_of_tumor-derived_exosome_tex-mediated_immunosuppression" action="/pathways/mechanisms-tumor-derived-exosome-tex-mediated-immunosuppression" method="post"> <li class=""> <a href="/pathways/mechanisms-tumor-derived-exosome-tex-mediated-immunosuppression" class="pathway_link" data-form="pathways_mechanisms_of_tumor-derived_exosome_tex-mediated_immunosuppression"> Mechanisms of Tumor-derived Exosome TEX-mediated Immunosuppression </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_natural_killer_cell_receptors__human_target_cell_–_nk_cell_ligand-receptor_interactions" action="/pathways/natural-killer-cell-receptors-human-target-cell-nk-cell-ligand-receptor-interactions-pathway" method="post"> <li class=""> <a href="/pathways/natural-killer-cell-receptors-human-target-cell-nk-cell-ligand-receptor-interactions-pathway" class="pathway_link" data-form="pathways_natural_killer_cell_receptors__human_target_cell_–_nk_cell_ligand-receptor_interactions"> Natural Killer Cell Receptors: Human Target Cell – NK Cell Ligand-Receptor Interactions </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_neuropoietin_signaling_pathways" action="/pathways/neuropoietin-signaling-pathways" method="post"> <li class=""> <a href="/pathways/neuropoietin-signaling-pathways" class="pathway_link" data-form="pathways_neuropoietin_signaling_pathways"> Neuropoietin Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_nod-like_receptor_signaling_pathways" action="/pathways/nod-like-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/nod-like-receptor-signaling-pathways" class="pathway_link" data-form="pathways_nod-like_receptor_signaling_pathways"> NOD-like Receptor Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_oncostatin_m_signaling_pathways" action="/pathways/oncostatin-m-signaling-pathways" method="post"> <li class=""> <a href="/pathways/oncostatin-m-signaling-pathways" class="pathway_link" data-form="pathways_oncostatin_m_signaling_pathways"> Oncostatin M Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_pathogen_or_damage-activated_c-type_lectin_receptor_signaling_pathways" action="/pathways/pathogen-damage-activated-c-type-lectin-receptor-signaling-pathways" method="post"> <li class="active"> <a href="/pathways/pathogen-damage-activated-c-type-lectin-receptor-signaling-pathways" class="pathway_link" data-form="pathways_pathogen_or_damage-activated_c-type_lectin_receptor_signaling_pathways"> Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_t_cell_co-signaling_pathway__ligand-receptor_interactions" action="/pathways/t-cell-co-signaling-pathway-lig-recept-interactions" method="post"> <li class=""> <a href="/pathways/t-cell-co-signaling-pathway-lig-recept-interactions" class="pathway_link" data-form="pathways_t_cell_co-signaling_pathway__ligand-receptor_interactions"> T Cell Co-Signaling Pathway: Ligand-Receptor Interactions </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_tgf-beta_signaling_pathways" action="/pathways/tgf-beta-signaling-pathways" method="post"> <li class=""> <a href="/pathways/tgf-beta-signaling-pathways" class="pathway_link" data-form="pathways_tgf-beta_signaling_pathways"> TGF-beta Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_th1_differentiation_pathway" action="/pathways/th1-differentiation-pathway" method="post"> <li class=""> <a href="/pathways/th1-differentiation-pathway" class="pathway_link" data-form="pathways_th1_differentiation_pathway"> Th1 Differentiation Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_th17_differentiation_pathway" action="/pathways/th17-differentiation-pathway" method="post"> <li class=""> <a href="/pathways/th17-differentiation-pathway" class="pathway_link" data-form="pathways_th17_differentiation_pathway"> Th17 Differentiation Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_th2_differentiation_pathway" action="/pathways/th2-differentiation-pathway" method="post"> <li class=""> <a href="/pathways/th2-differentiation-pathway" class="pathway_link" data-form="pathways_th2_differentiation_pathway"> Th2 Differentiation Pathway </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_tnf_superfamily_pathway__human_ligand-receptor_interactions__their_associated_functions" action="/pathways/tnf-superfamily-pathway-human-lig-recept-interactions-their-associated-functions" method="post"> <li class=""> <a href="/pathways/tnf-superfamily-pathway-human-lig-recept-interactions-their-associated-functions" class="pathway_link" data-form="pathways_tnf_superfamily_pathway__human_ligand-receptor_interactions__their_associated_functions"> TNF Superfamily Pathway: Human Ligand-Receptor Interactions & their Associated Functions </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_toll-like_receptor_signaling_pathways" action="/pathways/toll-like-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/toll-like-receptor-signaling-pathways" class="pathway_link" data-form="pathways_toll-like_receptor_signaling_pathways"> Toll-Like Receptor Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_type_i_interferon_signaling_pathways" action="/pathways/type-i-interferon-signaling-pathways" method="post"> <li class=""> <a href="/pathways/type-i-interferon-signaling-pathways" class="pathway_link" data-form="pathways_type_i_interferon_signaling_pathways"> Type I Interferon Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_type_ii_interferon_signaling_pathways" action="/pathways/type-ii-interferon-signaling-pathways" method="post"> <li class=""> <a href="/pathways/type-ii-interferon-signaling-pathways" class="pathway_link" data-form="pathways_type_ii_interferon_signaling_pathways"> Type II Interferon Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_type_iii_interferon_signaling_pathways" action="/pathways/type-iii-interferon-signaling-pathways" method="post"> <li class=""> <a href="/pathways/type-iii-interferon-signaling-pathways" class="pathway_link" data-form="pathways_type_iii_interferon_signaling_pathways"> Type III Interferon Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_vegf_-_vegf_r2_signaling_pathways" action="/pathways/vegf-vegf-r2-signaling-pathways" method="post"> <li class=""> <a href="/pathways/vegf-vegf-r2-signaling-pathways" class="pathway_link" data-form="pathways_vegf_-_vegf_r2_signaling_pathways"> VEGF - VEGF R2 Signaling Pathways </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> <form id="pathways_virus_detection_and_induction_of_antiviral_signaling_pathways_by_rig-i-like_receptors_rlr" action="/pathways/rig-i-like-receptor-signaling-pathways" method="post"> <li class=""> <a href="/pathways/rig-i-like-receptor-signaling-pathways" class="pathway_link" data-form="pathways_virus_detection_and_induction_of_antiviral_signaling_pathways_by_rig-i-like_receptors_rlr"> Virus Detection and Induction of Antiviral Signaling Pathways by RIG-I-like Receptors RLR </a> </li> <input type="hidden" name="pw_parent" value="Immunology"> </form> </ul> </li> <li class="pathways-li "> <form id="pathways_neuroscience_pathways" action="/pathways/neuroscience" method="post"> <a href="/pathways/neuroscience" data-form="pathways_neuroscience_pathways" class="pathway_link"> <span class="icon-"> Neuroscience Pathways </span> </a> <input type="hidden" name="pw_parent" value="Neuroscience"> </form> </li> <li class="pathways-li "> <form id="pathways_proteases__other_enzymes_pathways" action="/pathways/proteases" method="post"> <a href="/pathways/proteases" data-form="pathways_proteases__other_enzymes_pathways" class="pathway_link"> <span class="icon-"> Proteases & Other Enzymes Pathways </span> </a> <input type="hidden" name="pw_parent" value="proteases"> </form> </li> <li class="pathways-li "> <form id="pathways_signal_transduction_pathways" action="/pathways/signal-transduction" method="post"> <a href="/pathways/signal-transduction" data-form="pathways_signal_transduction_pathways" class="pathway_link"> <span class="icon-"> Signal Transduction Pathways </span> </a> <input type="hidden" name="pw_parent" value="signal-transduction"> </form> </li> <li class="pathways-li "> <form id="pathways_stem_cell_pathways" action="/pathways/stem-cells" method="post"> <a href="/pathways/stem-cells" data-form="pathways_stem_cell_pathways" class="pathway_link"> <span class="icon-"> Stem Cell Pathways </span> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </li> <li class="pathways-li "> <form id="pathways_ubiquitin_related_modifiers__pathways" action="/pathways/ubiquitin-related-modifiers-and-pathways" method="post"> <a href="/pathways/ubiquitin-related-modifiers-and-pathways" data-form="pathways_ubiquitin_related_modifiers__pathways" class="pathway_link"> <span class="icon-"> Ubiquitin, Related Modifiers, & Pathways </span> </a> <input type="hidden" name="pw_parent" value="ubiquitin-related-modifiers-and-pathways"> </form> </li> </ul> </div> </div> </div> </div> </div> <div class="pw_right col-xs-12 col-sm-8 col-md-9"> <div class="search_mobile_buttons"> <div class="pw_menu_toggle btn btn-tertiary">Show Categories</div> </div> <div class="pw_header"> <h1>Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways</h1> <p id="pw-intro-txt">Click on one of the C-type Lectin receptors shown in the Explore Pathways box below to see the pathogen- or damage-associated molecules recognized by each receptor & the intracellular signaling pathways that are activated as a result.<br></p> <div id="pw-con" data-mapname="" data-primary_segment="clr_all"> <div id="pw-main-nav-wrapper"> <div class="row"> <div id="pw-button-nav-top" class="col-xs-12 col-sm-12"> <div class="row"> <div id="pw-button-nav"> <div class="dropdown col-xs-12 col-sm-6 col-md-4"> <button class="btn-pw" type="button" data-toggle="dropup">Explore Pathways<span class="caret"></span></button> <ul id="pathwaynav" class="dropdown-content"> <li data-segment="CLR_BDCA2" data-background_image="CLR_BDCA2.png" data-pathway_segment="PATHWAY_CLR_BDCA2" class="pw_rdblue_sm pw_sm_btn"><span>BDCA-2</span></li> <li data-segment="CLR_DCIR" data-background_image="CLR_DCIR.png" data-pathway_segment="PATHWAY_CLR_DCIR" class="pw_rdblue_sm pw_sm_btn"><span>DCIR</span></li> <li data-segment="CLR_DCSIGN" data-background_image="CLR_DCSign.png" data-pathway_segment="PATHWAY_CLR_DCSIGN" class="pw_rdblue_sm pw_sm_btn"><span>DC-SIGN</span></li> <li data-segment="CLR_Dectin1" data-background_image="CLR_Dectin1.png" data-pathway_segment="PATHWAY_CLR_Dectin1" class="pw_rdblue_sm pw_sm_btn"><span>Dectin-1</span></li> <li data-segment="CLR_Dectin2" data-background_image="CLR_Dectin2.png" data-pathway_segment="PATHWAY_CLR_Dectin2" class="pw_rdblue_sm pw_sm_btn"><span>Dectin-2</span></li> <li data-segment="CLR_Mincle" data-background_image="CLR_Mincle.png" data-pathway_segment="PATHWAY_CLR_Mincle" class="pw_rdblue_sm pw_sm_btn"><span>Mincle</span></li> <li data-segment="CLR_MICL" data-background_image="CLR_MICL.png" data-pathway_segment="PATHWAY_CLR_MICL" class="pw_rdblue_sm pw_sm_btn"><span>MICL/CLEC12A</span></li> <li data-segment="CLR_All" data-background_image="CLR_All.png" data-pathway_segment="PATHWAY_CLR_All" class="pw_sm_btn-active"><span>View Full Pathway</span></li> </ul> </div> </div> <div class="col-xs-12 col-sm-6 col-md-5" > <div id="pw-nav-subtitle"> Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways </div> </div> <div id="pw-print-button-col" class="col-xs-12 col-sm-6 col-md-3" > <a href="#print-copy-form" id="btn-get-print-copy" class="btn btn-primary"><img class="btn-icon" src="https://resources.rndsystems.com/images/Pathways/icons/icon-image.svg"/> Get Print Copy</a> </div> </div> </div> </div> </div> <div id="pw-map"> <div id="pw-maps"> <div id="el1_gry" class="clr_all clr_dcsign pw-sprite el-gray1 pw-gray" style="top:48px;left:74px;"> </div> <div id="el1_off" data-id="1" data-set="DC-SIGN1" data-type="" class="clr_all clr_dcsign pw-sprite el-off1" style="top:48px;left:74px;"> </div> <div id="el1_ct" class="pw-tooltip" data-id="1"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209</a><br> </div> </div> <div id="el2_gry" class="clr_all clr_dcsign pw-label el-gray2 pw-gray" style="top:39px;left:68px;"> DC-SIGN </div> <div id="el2_off" data-id="2" data-set="DC-SIGN1" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off2" style="top:39px;left:68px;"> DC-SIGN</div> <div id="el2_ct" class="pw-tooltip" data-id="2"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dc-sign-cd209">DC-SIGN/CD209</a><br> </div> </div> <div id="el3_gry" class="clr_all clr_dcsign pw-sprite el-gray3 pw-gray" style="top:115.99996948242188px;left:69px;"> </div> <div id="el3_off" data-id="3" data-set="LSP12" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off3" style="top:115.99996948242188px;left:69px;"> </div> <div id="el3_ct" class="pw-tooltip" data-id="3"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=LSP1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el4_gry" class="clr_all clr_dcsign pw-label el-gray4 pw-gray" style="top:123.99996948242188px;left:53px;"> LSP1 </div> <div id="el4_off" data-id="4" data-set="LSP12" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off4" style="top:123.99996948242188px;left:53px;"> LSP1</div> <div id="el4_ct" class="pw-tooltip" data-id="4"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=LSP1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el5_gry" class="clr_all clr_dcsign pw-sprite el-gray5 pw-gray" style="top:111.99996948242188px;left:82px;"> </div> <div id="el5_off" data-id="5" data-set="KSR3" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off5" style="top:111.99996948242188px;left:82px;"> </div> <div id="el5_ct" class="pw-tooltip" data-id="5"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=KSR">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el6_gry" class="clr_all clr_dcsign pw-label el-gray6 pw-gray" style="top:118.99996948242188px;left:94px;"> KSR </div> <div id="el6_off" data-id="6" data-set="KSR3" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off6" style="top:118.99996948242188px;left:94px;"> KSR</div> <div id="el6_ct" class="pw-tooltip" data-id="6"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=KSR">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el7_gry" class="clr_all clr_dcsign pw-sprite el-gray7 pw-gray" style="top:123.99996948242188px;left:79px;"> </div> <div id="el7_off" data-id="7" data-set="CNK4" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off7" style="top:123.99996948242188px;left:79px;"> </div> <div id="el7_ct" class="pw-tooltip" data-id="7"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=CNKSR1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el8_gry" class="clr_all clr_dcsign pw-label el-gray8 pw-gray" style="top:132.99996948242188px;left:90px;"> CNK </div> <div id="el8_off" data-id="8" data-set="CNK4" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off8" style="top:132.99996948242188px;left:90px;"> CNK</div> <div id="el8_ct" class="pw-tooltip" data-id="8"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=CNKSR1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el9_gry" class="clr_all clr_dcsign pw-sprite el-gray9 pw-gray" style="top:149px;left:21px;"> </div> <div id="el9_off" data-id="9" data-set="Ras5" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off9" style="top:149px;left:21px;"> </div> <div id="el9_ct" class="pw-tooltip" data-id="9"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ras">Ras</a><br> </div> </div> <div id="el10_gry" class="clr_all clr_dcsign pw-label el-gray10 pw-gray" style="top:156px;left:23px;"> Ras </div> <div id="el10_off" data-id="10" data-set="Ras5" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off10" style="top:156px;left:23px;"> Ras</div> <div id="el10_ct" class="pw-tooltip" data-id="10"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ras">Ras</a><br> </div> </div> <div id="el11_gry" class="clr_all clr_dcsign pw-sprite el-gray11 pw-gray" style="top:233px;left:3px;"> </div> <div id="el11_off" data-id="11" data-set="Raf-16" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off11" style="top:233px;left:3px;"> </div> <div id="el11_ct" class="pw-tooltip" data-id="11"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/raf-1">Raf-1</a><br> </div> </div> <div id="el12_gry" class="clr_all clr_dcsign pw-label el-gray12 pw-gray" style="top:241px;left:6px;"> Raf-1 </div> <div id="el12_off" data-id="12" data-set="Raf-16" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off12" style="top:241px;left:6px;"> Raf-1</div> <div id="el12_ct" class="pw-tooltip" data-id="12"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/raf-1">Raf-1</a><br> </div> </div> <div id="el13_gry" class="clr_all clr_dcsign pw-sprite el-gray13 pw-gray" style="top:315px;left:11px;"> </div> <div id="el13_off" data-id="13" data-set="MEK7" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off13" style="top:315px;left:11px;"> </div> <div id="el13_ct" class="pw-tooltip" data-id="13"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/mek1-mek2">MEK1/MEK2</a><br> <a target="_blank" href="/target/mek1">MEK1</a><br> <a target="_blank" href="/target/mek2">MEK2</a><br> </div> </div> <div id="el14_gry" class="clr_all clr_dcsign pw-label el-gray14 pw-gray" style="top:322.9999694824219px;left:13px;"> MEK </div> <div id="el14_off" data-id="14" data-set="MEK7" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off14" style="top:322.9999694824219px;left:13px;"> MEK</div> <div id="el14_ct" class="pw-tooltip" data-id="14"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/mek1-mek2">MEK1/MEK2</a><br> <a target="_blank" href="/target/mek1">MEK1</a><br> <a target="_blank" href="/target/mek2">MEK2</a><br> </div> </div> <div id="el15_gry" class="clr_all clr_dcsign pw-label2 pw-center el-gray15 pw-gray" style="top:393.9999694824219px;left:25px;"> <div class="pw_txtBox">TNF, IL-6<br>mRNA Decay</div> </div> <div id="el15_off" data-id="15" data-set="TNF" data-type="" class="clr_all clr_dcsign pw-label2 pw-center el-off15" style="top:393.9999694824219px;left:25px;"> <div class="pw_txtBox">TNF, IL-6<br>mRNA Decay</div></div> <div id="el15_ct" class="pw-tooltip" data-id="15"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el16_gry" class="clr_all clr_dcsign pw-sprite el-gray16 pw-gray" style="top:193px;left:42px;"> </div> <div id="el16_off" data-id="16" data-set="LARG9" data-type="" class="clr_all clr_dcsign pw-sprite el-off16" style="top:193px;left:42px;"> </div> <div id="el16_ct" class="pw-tooltip" data-id="16"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/larg">LARG</a><br> </div> </div> <div id="el17_gry" class="clr_all clr_dcsign pw-label el-gray17 pw-gray" style="top:201px;left:42px;"> LARG </div> <div id="el17_off" data-id="17" data-set="LARG9" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off17" style="top:201px;left:42px;"> LARG</div> <div id="el17_ct" class="pw-tooltip" data-id="17"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/larg">LARG</a><br> </div> </div> <div id="el18_gry" class="clr_all clr_dcsign pw-sprite el-gray18 pw-gray" style="top:279px;left:52px;"> </div> <div id="el18_off" data-id="18" data-set="RhoA10" data-type="No Products Click" class="clr_all clr_dcsign pw-sprite el-off18" style="top:279px;left:52px;"> </div> <div id="el18_ct" class="pw-tooltip" data-id="18"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=RhoA">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el19_gry" class="clr_all clr_dcsign pw-label el-gray19 pw-gray" style="top:284.9999694824219px;left:53px;"> RhoA </div> <div id="el19_off" data-id="19" data-set="RhoA10" data-type="No Products Click" class="clr_all clr_dcsign pw-label el-off19" style="top:284.9999694824219px;left:53px;"> RhoA</div> <div id="el19_ct" class="pw-tooltip" data-id="19"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=RhoA">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el20_gry" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-gray20 pw-gray" style="top:91px;left:148px;"> </div> <div id="el20_off" data-id="20" data-set="Ras11" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-off20" style="top:91px;left:148px;"> </div> <div id="el20_ct" class="pw-tooltip" data-id="20"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ras">Ras</a><br> </div> </div> <div id="el21_gry" class="clr_all clr_dcsign clr_dectin1 pw-label el-gray21 pw-gray" style="top:98.99996948242188px;left:159px;"> Ras </div> <div id="el21_off" data-id="21" data-set="Ras11" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-label el-off21" style="top:98.99996948242188px;left:159px;"> Ras</div> <div id="el21_ct" class="pw-tooltip" data-id="21"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ras">Ras</a><br> </div> </div> <div id="el22_gry" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-gray22 pw-gray" style="top:469.9999694824219px;left:99px;"> </div> <div id="el22_off" data-id="22" data-set="Raf-112" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-off22" style="top:469.9999694824219px;left:99px;"> </div> <div id="el22_ct" class="pw-tooltip" data-id="22"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/raf-1">Raf-1</a><br> </div> </div> <div id="el23_gry" class="clr_all clr_dcsign clr_dectin1 pw-label el-gray23 pw-gray" style="top:479px;left:110px;"> Raf-1 </div> <div id="el23_off" data-id="23" data-set="Raf-112" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-label el-off23" style="top:479px;left:110px;"> Raf-1</div> <div id="el23_ct" class="pw-tooltip" data-id="23"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/raf-1">Raf-1</a><br> </div> </div> <div id="el24_gry" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-gray24 pw-gray" style="top:903px;left:51px;"> </div> <div id="el24_off" data-id="24" data-set="NF-kappaBp6513" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-off24" style="top:903px;left:51px;"> </div> <div id="el24_ct" class="pw-tooltip" data-id="24"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/rela-nfkb-p65">RelA/NFkB p65</a><br> </div> </div> <div id="el25_gry" class="clr_all clr_dcsign clr_dectin1 pw-label el-gray25 pw-gray" style="top:888px;left:25px;"> NF-kappa B p65 </div> <div id="el25_off" data-id="25" data-set="NF-kappaBp6513" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-label el-off25" style="top:888px;left:25px;"> NF-kappa B p65</div> <div id="el25_ct" class="pw-tooltip" data-id="25"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/rela-nfkb-p65">RelA/NFkB p65</a><br> </div> </div> <div id="el26_gry" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-gray26 pw-gray" style="top:903px;left:65px;"> </div> <div id="el26_off" data-id="26" data-set="RelB14" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-sprite el-off26" style="top:903px;left:65px;"> </div> <div id="el26_ct" class="pw-tooltip" data-id="26"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el27_gry" class="clr_all clr_dcsign clr_dectin1 pw-label el-gray27 pw-gray" style="top:910.9999694824219px;left:78px;"> RelB </div> <div id="el27_off" data-id="27" data-set="RelB14" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 pw-label el-off27" style="top:910.9999694824219px;left:78px;"> RelB</div> <div id="el27_ct" class="pw-tooltip" data-id="27"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el28_gry" class="clr_all clr_dcsign clr_dectin1 pw-label2 el-gray28 pw-gray" style="top:932.9999694824219px;left:50px;"> Inactive </div> <div id="el28_off" data-id="28" data-set="Inactive" data-type="" class="clr_all clr_dcsign clr_dectin1 pw-label2 el-off28" style="top:932.9999694824219px;left:50px;"> Inactive</div> <div id="el28_ct" class="pw-tooltip" data-id="28"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el29_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray29 pw-gray" style="top:915px;left:224px;"> </div> <div id="el29_off" data-id="29" data-set="NF-kappaBp6516" data-type="" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off29" style="top:915px;left:224px;"> </div> <div id="el29_ct" class="pw-tooltip" data-id="29"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/rela-nfkb-p65">RelA/NFkB p65</a><br> </div> </div> <div id="el30_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray30 pw-gray" style="top:883px;left:200px;"> NF-kappa B p65 </div> <div id="el30_off" data-id="30" data-set="NF-kappaBp6516" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-off30" style="top:883px;left:200px;"> NF-kappa B p65</div> <div id="el30_ct" class="pw-tooltip" data-id="30"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/rela-nfkb-p65">RelA/NFkB p65</a><br> </div> </div> <div id="el31_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray31 pw-gray" style="top:914px;left:237px;"> </div> <div id="el31_off" data-id="31" data-set="NF-kappaBp5017" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off31" style="top:914px;left:237px;"> </div> <div id="el31_ct" class="pw-tooltip" data-id="31"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb1">NFkB1</a><br> </div> </div> <div id="el32_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray32 pw-gray" style="top:909px;left:252px;"> NF-kappa B p50 </div> <div id="el32_off" data-id="32" data-set="NF-kappaBp5017" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-off32" style="top:909px;left:252px;"> NF-kappa B p50</div> <div id="el32_ct" class="pw-tooltip" data-id="32"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb1">NFkB1</a><br> </div> </div> <div id="el33_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray33 pw-gray" style="top:912px;left:212px;"> </div> <div id="el33_off" data-id="33" data-set="CBP18" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off33" style="top:912px;left:212px;"> </div> <div id="el33_ct" class="pw-tooltip" data-id="33"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cbp">CBP</a><br> </div> </div> <div id="el34_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray34 pw-gray" style="top:918px;left:205px;"> CBP </div> <div id="el34_off" data-id="34" data-set="CBP18" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-off34" style="top:918px;left:205px;"> CBP</div> <div id="el34_ct" class="pw-tooltip" data-id="34"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/cbp">CBP</a><br> </div> </div> <div id="el35_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray35 pw-gray" style="top:925px;left:214px;"> </div> <div id="el35_off" data-id="35" data-set="p30019" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off35" style="top:925px;left:214px;"> </div> <div id="el35_ct" class="pw-tooltip" data-id="35"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/p300">p300</a><br> </div> </div> <div id="el36_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray36 pw-gray" style="top:934px;left:206px;"> p300 </div> <div id="el36_off" data-id="36" data-set="p30019" data-type="No Products Click" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label el-off36" style="top:934px;left:206px;"> p300</div> <div id="el36_ct" class="pw-tooltip" data-id="36"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/p300">p300</a><br> </div> </div> <div id="el37_gry" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label2 el-gray37 pw-gray" style="top:985.9999694824219px;left:237px;"> Pro-inflammatory Cytokines </div> <div id="el37_off" data-id="37" data-set="Pro-inflammatoryCytokines" data-type="" class="clr_all clr_dcsign clr_dectin1 clr_dectin2 clr_mincle pw-label2 el-off37" style="top:985.9999694824219px;left:237px;"> Pro-inflammatory Cytokines</div> <div id="el37_ct" class="pw-tooltip" data-id="37"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el38_gry" class="clr_all clr_dectin1 pw-sprite el-gray38 pw-gray" style="top:29px;left:201px;"> </div> <div id="el38_off" data-id="38" data-set="Dectin-121" data-type="" class="clr_all clr_dectin1 pw-sprite el-off38" style="top:29px;left:201px;"> </div> <div id="el38_ct" class="pw-tooltip" data-id="38"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dectin-1-clec7a">Dectin-1/CLEC7A</a><br> </div> </div> <div id="el39_gry" class="clr_all clr_dectin1 pw-label el-gray39 pw-gray" style="top:21px;left:207px;"> Dectin-1 </div> <div id="el39_off" data-id="39" data-set="Dectin-121" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off39" style="top:21px;left:207px;"> Dectin-1</div> <div id="el39_ct" class="pw-tooltip" data-id="39"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dectin-1-clec7a">Dectin-1/CLEC7A</a><br> </div> </div> <div id="el40_gry" class="clr_all clr_dectin1 pw-sprite el-gray40 pw-gray" style="top:86px;left:218px;"> </div> <div id="el40_off" data-id="40" data-set="SYK22" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off40" style="top:86px;left:218px;"> </div> <div id="el40_ct" class="pw-tooltip" data-id="40"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el41_gry" class="clr_all clr_dectin1 pw-label el-gray41 pw-gray" style="top:106px;left:221px;"> SYK </div> <div id="el41_off" data-id="41" data-set="SYK22" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off41" style="top:106px;left:221px;"> SYK</div> <div id="el41_ct" class="pw-tooltip" data-id="41"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el42_gry" class="clr_all clr_dectin1 clr_mincle pw-sprite el-gray42 pw-gray" style="top:84px;left:263px;"> </div> <div id="el42_off" data-id="42" data-set="Src23" data-type="No Products Click" class="clr_all clr_dectin1 clr_mincle pw-sprite el-off42" style="top:84px;left:263px;"> </div> <div id="el42_ct" class="pw-tooltip" data-id="42"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/src">Src</a><br> </div> </div> <div id="el43_gry" class="clr_all clr_dectin1 clr_mincle pw-label el-gray43 pw-gray" style="top:91px;left:274px;"> Src </div> <div id="el43_off" data-id="43" data-set="Src23" data-type="No Products Click" class="clr_all clr_dectin1 clr_mincle pw-label el-off43" style="top:91px;left:274px;"> Src</div> <div id="el43_ct" class="pw-tooltip" data-id="43"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/src">Src</a><br> </div> </div> <div id="el44_gry" class="clr_all clr_dectin1 pw-sprite el-gray44 pw-gray" style="top:157px;left:155px;"> </div> <div id="el44_off" data-id="44" data-set="NIK24" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off44" style="top:157px;left:155px;"> </div> <div id="el44_ct" class="pw-tooltip" data-id="44"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nik-map3k14">NIK/MAP3K14</a><br> </div> </div> <div id="el45_gry" class="clr_all clr_dectin1 pw-label el-gray45 pw-gray" style="top:164.99996948242188px;left:161px;"> NIK </div> <div id="el45_off" data-id="45" data-set="NIK24" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off45" style="top:164.99996948242188px;left:161px;"> NIK</div> <div id="el45_ct" class="pw-tooltip" data-id="45"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nik-map3k14">NIK/MAP3K14</a><br> </div> </div> <div id="el46_gry" class="clr_all clr_dectin1 pw-sprite el-gray46 pw-gray" style="top:259px;left:149px;"> </div> <div id="el46_off" data-id="46" data-set="IKKalpha25" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off46" style="top:259px;left:149px;"> </div> <div id="el46_ct" class="pw-tooltip" data-id="46"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikk-alpha">IKK alpha</a><br> </div> </div> <div id="el47_gry" class="clr_all clr_dectin1 pw-label el-gray47 pw-gray" style="top:264.9999694824219px;left:137px;"> IKK alpha </div> <div id="el47_off" data-id="47" data-set="IKKalpha25" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off47" style="top:264.9999694824219px;left:137px;"> IKK alpha</div> <div id="el47_ct" class="pw-tooltip" data-id="47"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikk-alpha">IKK alpha</a><br> </div> </div> <div id="el48_gry" class="clr_all clr_dectin1 pw-sprite el-gray48 pw-gray" style="top:390px;left:220px;"> </div> <div id="el48_off" data-id="48" data-set="NF-kappaBp10026" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off48" style="top:390px;left:220px;"> </div> <div id="el48_ct" class="pw-tooltip" data-id="48"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> </div> </div> <div id="el49_gry" class="clr_all clr_dectin1 pw-label el-gray49 pw-gray" style="top:397px;left:140px;"> NF-kappa B p100 </div> <div id="el49_off" data-id="49" data-set="NF-kappaBp10026" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off49" style="top:397px;left:140px;"> NF-kappa B p100</div> <div id="el49_ct" class="pw-tooltip" data-id="49"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> </div> </div> <div id="el50_gry" class="clr_all clr_dectin1 pw-sprite el-gray50 pw-gray" style="top:389px;left:231px;"> </div> <div id="el50_off" data-id="50" data-set="RelB27" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off50" style="top:389px;left:231px;"> </div> <div id="el50_ct" class="pw-tooltip" data-id="50"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el51_gry" class="clr_all clr_dectin1 pw-label el-gray51 pw-gray" style="top:397px;left:245px;"> RelB </div> <div id="el51_off" data-id="51" data-set="RelB27" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off51" style="top:397px;left:245px;"> RelB</div> <div id="el51_ct" class="pw-tooltip" data-id="51"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el52_gry" class="clr_all clr_dectin1 pw-sprite el-gray52 pw-gray" style="top:636px;left:128px;"> </div> <div id="el52_off" data-id="52" data-set="NF-kappaBp5228" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off52" style="top:636px;left:128px;"> </div> <div id="el52_ct" class="pw-tooltip" data-id="52"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> </div> </div> <div id="el53_gry" class="clr_all clr_dectin1 pw-label el-gray53 pw-gray" style="top:642.9999694824219px;left:57px;"> NF-kappa B p52 </div> <div id="el53_off" data-id="53" data-set="NF-kappaBp5228" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off53" style="top:642.9999694824219px;left:57px;"> NF-kappa B p52</div> <div id="el53_ct" class="pw-tooltip" data-id="53"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> </div> </div> <div id="el54_gry" class="clr_all clr_dectin1 pw-sprite el-gray54 pw-gray" style="top:635px;left:142px;"> </div> <div id="el54_off" data-id="54" data-set="RelB29" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off54" style="top:635px;left:142px;"> </div> <div id="el54_ct" class="pw-tooltip" data-id="54"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el55_gry" class="clr_all clr_dectin1 pw-label el-gray55 pw-gray" style="top:642.9999694824219px;left:155px;"> RelB </div> <div id="el55_off" data-id="55" data-set="RelB29" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off55" style="top:642.9999694824219px;left:155px;"> RelB</div> <div id="el55_ct" class="pw-tooltip" data-id="55"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el56_gry" class="clr_all clr_dectin1 pw-sprite el-gray56 pw-gray" style="top:832px;left:211px;"> </div> <div id="el56_off" data-id="56" data-set="NF-kappaBp5230" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off56" style="top:832px;left:211px;"> </div> <div id="el56_ct" class="pw-tooltip" data-id="56"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> </div> </div> <div id="el57_gry" class="clr_all clr_dectin1 pw-label el-gray57 pw-gray" style="top:812px;left:157px;"> NF-kappa B p52 </div> <div id="el57_off" data-id="57" data-set="NF-kappaBp5230" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off57" style="top:812px;left:157px;"> NF-kappa B p52</div> <div id="el57_ct" class="pw-tooltip" data-id="57"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> </div> </div> <div id="el58_gry" class="clr_all clr_dectin1 pw-sprite el-gray58 pw-gray" style="top:831px;left:224px;"> </div> <div id="el58_off" data-id="58" data-set="RelB31" data-type="No Products Click" class="clr_all clr_dectin1 pw-sprite el-off58" style="top:831px;left:224px;"> </div> <div id="el58_ct" class="pw-tooltip" data-id="58"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el59_gry" class="clr_all clr_dectin1 pw-label el-gray59 pw-gray" style="top:826px;left:232px;"> RelB </div> <div id="el59_off" data-id="59" data-set="RelB31" data-type="No Products Click" class="clr_all clr_dectin1 pw-label el-off59" style="top:826px;left:232px;"> RelB</div> <div id="el59_ct" class="pw-tooltip" data-id="59"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> </div> </div> <div id="el60_gry" class="clr_all clr_dectin1 pw-label2 pw-center el-gray60 pw-gray" style="top:188px;left:233px;"> ROS </div> <div id="el60_off" data-id="60" data-set="ROS" data-type="" class="clr_all clr_dectin1 pw-label2 pw-center el-off60" style="top:188px;left:233px;"> ROS</div> <div id="el60_ct" class="pw-tooltip" data-id="60"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el61_gry" class="clr_all clr_mincle pw-sprite el-gray61 pw-gray" style="top:19px;left:287px;"> </div> <div id="el61_off" data-id="61" data-set="Mincle33" data-type="" class="clr_all clr_mincle pw-sprite el-off61" style="top:19px;left:287px;"> </div> <div id="el61_ct" class="pw-tooltip" data-id="61"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/clec4e">CLEC4E</a><br> </div> </div> <div id="el62_gry" class="clr_all clr_mincle pw-label el-gray62 pw-gray" style="top:9px;left:285px;"> Mincle </div> <div id="el62_off" data-id="62" data-set="Mincle33" data-type="No Products Click" class="clr_all clr_mincle pw-label el-off62" style="top:9px;left:285px;"> Mincle</div> <div id="el62_ct" class="pw-tooltip" data-id="62"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/clec4e">CLEC4E</a><br> </div> </div> <div id="el63_gry" class="clr_all clr_mincle pw-sprite el-gray63 pw-gray" style="top:47px;left:296px;"> </div> <div id="el63_off" data-id="63" data-set="FcRgamma34" data-type="No Products Click" class="clr_all clr_mincle pw-sprite el-off63" style="top:47px;left:296px;"> </div> <div id="el63_ct" class="pw-tooltip" data-id="63"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Fc%20receptor%20gamma-chain%20">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el64_gry" class="clr_all clr_mincle pw-label el-gray64 pw-gray" style="top:40px;left:308px;"> FcR gamma </div> <div id="el64_off" data-id="64" data-set="FcRgamma34" data-type="No Products Click" class="clr_all clr_mincle pw-label el-off64" style="top:40px;left:308px;"> FcR gamma</div> <div id="el64_ct" class="pw-tooltip" data-id="64"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Fc%20receptor%20gamma-chain%20">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el65_gry" class="clr_all clr_mincle pw-label2 pw-center el-gray65 pw-gray" style="top:125px;left:364px;"> ROS </div> <div id="el65_off" data-id="65" data-set="ROS" data-type="" class="clr_all clr_mincle pw-label2 pw-center el-off65" style="top:125px;left:364px;"> ROS</div> <div id="el65_ct" class="pw-tooltip" data-id="65"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el66_gry" class="clr_all clr_mincle pw-sprite el-gray66 pw-gray" style="top:78px;left:320px;"> </div> <div id="el66_off" data-id="66" data-set="SYK36" data-type="" class="clr_all clr_mincle pw-sprite el-off66" style="top:78px;left:320px;"> </div> <div id="el66_ct" class="pw-tooltip" data-id="66"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el67_gry" class="clr_all clr_mincle pw-label el-gray67 pw-gray" style="top:85px;left:332px;"> SYK </div> <div id="el67_off" data-id="67" data-set="SYK36" data-type="No Products Click" class="clr_all clr_mincle pw-label el-off67" style="top:85px;left:332px;"> SYK</div> <div id="el67_ct" class="pw-tooltip" data-id="67"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el68_gry" class="clr_all clr_dectin2 pw-sprite el-gray68 pw-gray" style="top:16px;left:377px;"> </div> <div id="el68_off" data-id="68" data-set="Dectin-237" data-type="No Products Click" class="clr_all clr_dectin2 pw-sprite el-off68" style="top:16px;left:377px;"> </div> <div id="el68_ct" class="pw-tooltip" data-id="68"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dectin-2-clec6a">Dectin-2/CLEC6A</a><br> </div> </div> <div id="el69_gry" class="clr_all clr_dectin2 pw-label el-gray69 pw-gray" style="top:6px;left:366px;"> Dectin-2 </div> <div id="el69_off" data-id="69" data-set="Dectin-237" data-type="No Products Click" class="clr_all clr_dectin2 pw-label el-off69" style="top:6px;left:366px;"> Dectin-2</div> <div id="el69_ct" class="pw-tooltip" data-id="69"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dectin-2-clec6a">Dectin-2/CLEC6A</a><br> </div> </div> <div id="el70_gry" class="clr_all clr_dectin2 pw-sprite el-gray70 pw-gray" style="top:45px;left:387px;"> </div> <div id="el70_off" data-id="70" data-set="FcRgamma38" data-type="No Products Click" class="clr_all clr_dectin2 pw-sprite el-off70" style="top:45px;left:387px;"> </div> <div id="el70_ct" class="pw-tooltip" data-id="70"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Fc%20receptor%20gamma-chain%20">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el71_gry" class="clr_all clr_dectin2 pw-label el-gray71 pw-gray" style="top:38px;left:400px;"> FcR gamma </div> <div id="el71_off" data-id="71" data-set="FcRgamma38" data-type="No Products Click" class="clr_all clr_dectin2 pw-label el-off71" style="top:38px;left:400px;"> FcR gamma</div> <div id="el71_ct" class="pw-tooltip" data-id="71"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Fc%20receptor%20gamma-chain%20">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el72_gry" class="clr_all clr_dectin2 pw-sprite el-gray72 pw-gray" style="top:78px;left:413px;"> </div> <div id="el72_off" data-id="72" data-set="SYK39" data-type="No Products Click" class="clr_all clr_dectin2 pw-sprite el-off72" style="top:78px;left:413px;"> </div> <div id="el72_ct" class="pw-tooltip" data-id="72"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el73_gry" class="clr_all clr_dectin2 pw-label el-gray73 pw-gray" style="top:86px;left:424px;"> SYK </div> <div id="el73_off" data-id="73" data-set="SYK39" data-type="No Products Click" class="clr_all clr_dectin2 pw-label el-off73" style="top:86px;left:424px;"> SYK</div> <div id="el73_ct" class="pw-tooltip" data-id="73"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el74_gry" class="clr_all clr_dectin2 pw-sprite el-gray74 pw-gray" style="top:88px;left:453px;"> </div> <div id="el74_off" data-id="74" data-set="Src40" data-type="No Products Click" class="clr_all clr_dectin2 pw-sprite el-off74" style="top:88px;left:453px;"> </div> <div id="el74_ct" class="pw-tooltip" data-id="74"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/src">Src</a><br> </div> </div> <div id="el75_gry" class="clr_all clr_dectin2 pw-label el-gray75 pw-gray" style="top:96px;left:464px;"> Src </div> <div id="el75_off" data-id="75" data-set="Src40" data-type="No Products Click" class="clr_all clr_dectin2 pw-label el-off75" style="top:96px;left:464px;"> Src</div> <div id="el75_ct" class="pw-tooltip" data-id="75"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/src">Src</a><br> </div> </div> <div id="el76_gry" class="clr_all clr_dectin2 pw-label2 pw-center el-gray76 pw-gray" style="top:188px;left:439px;"> ROS </div> <div id="el76_off" data-id="76" data-set="ROS" data-type="" class="clr_all clr_dectin2 pw-label2 pw-center el-off76" style="top:188px;left:439px;"> ROS</div> <div id="el76_ct" class="pw-tooltip" data-id="76"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el77_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray77 pw-gray" style="top:236px;left:332px;"> </div> <div id="el77_off" data-id="77" data-set="PLC-gamma242" data-type="" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off77" style="top:236px;left:332px;"> </div> <div id="el77_ct" class="pw-tooltip" data-id="77"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/plc-gamma-2">PLC-gamma 2</a><br> </div> </div> <div id="el78_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray78 pw-gray" style="top:241.99996948242188px;left:305px;"> PLC-gamma 2 </div> <div id="el78_off" data-id="78" data-set="PLC-gamma242" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off78" style="top:241.99996948242188px;left:305px;"> PLC-gamma 2</div> <div id="el78_ct" class="pw-tooltip" data-id="78"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/plc-gamma-2">PLC-gamma 2</a><br> </div> </div> <div id="el79_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray79 pw-gray" style="top:291.9999694824219px;left:328px;"> </div> <div id="el79_off" data-id="79" data-set="PIP243" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off79" style="top:291.9999694824219px;left:328px;"> </div> <div id="el79_ct" class="pw-tooltip" data-id="79"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=PIP2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el80_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray80 pw-gray" style="top:298.9999694824219px;left:331px;"> PIP<sub>2</sub> </div> <div id="el80_off" data-id="80" data-set="PIP243" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off80" style="top:298.9999694824219px;left:331px;"> PIP<sub>2</sub></div> <div id="el80_ct" class="pw-tooltip" data-id="80"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=PIP2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el81_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray81 pw-gray" style="top:336.9999694824219px;left:279px;"> </div> <div id="el81_off" data-id="81" data-set="DAG44" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off81" style="top:336.9999694824219px;left:279px;"> </div> <div id="el81_ct" class="pw-tooltip" data-id="81"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DAG">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el82_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray82 pw-gray" style="top:344.9999694824219px;left:272px;"> DAG </div> <div id="el82_off" data-id="82" data-set="DAG44" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off82" style="top:344.9999694824219px;left:272px;"> DAG</div> <div id="el82_ct" class="pw-tooltip" data-id="82"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DAG">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el83_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray83 pw-gray" style="top:361.9999694824219px;left:384px;"> </div> <div id="el83_off" data-id="83" data-set="IP345" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off83" style="top:361.9999694824219px;left:384px;"> </div> <div id="el83_ct" class="pw-tooltip" data-id="83"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=IP3">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el84_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray84 pw-gray" style="top:370px;left:396px;"> IP<sub>3</sub> </div> <div id="el84_off" data-id="84" data-set="IP345" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off84" style="top:370px;left:396px;"> IP<sub>3</sub></div> <div id="el84_ct" class="pw-tooltip" data-id="84"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=IP3">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el85_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray85 pw-gray" style="top:398px;left:266px;"> </div> <div id="el85_off" data-id="85" data-set="PKCdelta46" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off85" style="top:398px;left:266px;"> </div> <div id="el85_ct" class="pw-tooltip" data-id="85"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pkc-delta">PKC delta</a><br> <a target="_blank" href="/target/protein-kinase-c-activators">Protein Kinase C Activators</a><br> <a target="_blank" href="/target/protein-kinase-c-inhibitors">Protein Kinase C Inhibitors</a><br> </div> </div> <div id="el86_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray86 pw-gray" style="top:404.9999694824219px;left:278px;"> PKC delta </div> <div id="el86_off" data-id="86" data-set="PKCdelta46" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off86" style="top:404.9999694824219px;left:278px;"> PKC delta</div> <div id="el86_ct" class="pw-tooltip" data-id="86"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pkc-delta">PKC delta</a><br> <a target="_blank" href="/target/protein-kinase-c-activators">Protein Kinase C Activators</a><br> <a target="_blank" href="/target/protein-kinase-c-inhibitors">Protein Kinase C Inhibitors</a><br> </div> </div> <div id="el87_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray87 pw-gray" style="top:469px;left:306px;"> </div> <div id="el87_off" data-id="87" data-set="Bcl-1047" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off87" style="top:469px;left:306px;"> </div> <div id="el87_ct" class="pw-tooltip" data-id="87"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bcl-10">Bcl-10</a><br> </div> </div> <div id="el88_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray88 pw-gray" style="top:477px;left:286px;"> Bcl-10 </div> <div id="el88_off" data-id="88" data-set="Bcl-1047" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off88" style="top:477px;left:286px;"> Bcl-10</div> <div id="el88_ct" class="pw-tooltip" data-id="88"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bcl-10">Bcl-10</a><br> </div> </div> <div id="el89_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray89 pw-gray" style="top:455px;left:317px;"> </div> <div id="el89_off" data-id="89" data-set="CARD948" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off89" style="top:455px;left:317px;"> </div> <div id="el89_ct" class="pw-tooltip" data-id="89"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/card9">CARD9</a><br> </div> </div> <div id="el90_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray90 pw-gray" style="top:461px;left:327px;"> CARD9 </div> <div id="el90_off" data-id="90" data-set="CARD948" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off90" style="top:461px;left:327px;"> CARD9</div> <div id="el90_ct" class="pw-tooltip" data-id="90"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/card9">CARD9</a><br> </div> </div> <div id="el91_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray91 pw-gray" style="top:468.9999694824219px;left:322px;"> </div> <div id="el91_off" data-id="91" data-set="MALT149" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off91" style="top:468.9999694824219px;left:322px;"> </div> <div id="el91_ct" class="pw-tooltip" data-id="91"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/malt1">MALT1</a><br> </div> </div> <div id="el92_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray92 pw-gray" style="top:489.9999694824219px;left:329px;"> MALT1 </div> <div id="el92_off" data-id="92" data-set="MALT149" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off92" style="top:489.9999694824219px;left:329px;"> MALT1</div> <div id="el92_ct" class="pw-tooltip" data-id="92"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/malt1">MALT1</a><br> </div> </div> <div id="el93_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray93 pw-gray" style="top:560px;left:274px;"> </div> <div id="el93_off" data-id="93" data-set="IKK50" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off93" style="top:560px;left:274px;"> </div> <div id="el93_ct" class="pw-tooltip" data-id="93"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikk-alpha">IKK alpha</a><br> <a target="_blank" href="/target/ikk-beta">IKK beta</a><br> <a target="_blank" href="/target/ikk-gamma">IKK gamma</a><br> <a target="_blank" href="/target/ikk-epsilon">IKK epsilon</a><br> <a target="_blank" href="/search?keywords=ikk*">All IKK Products</a><br> </div> </div> <div id="el94_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray94 pw-gray" style="top:567px;left:281px;"> IKK </div> <div id="el94_off" data-id="94" data-set="IKK50" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off94" style="top:567px;left:281px;"> IKK</div> <div id="el94_ct" class="pw-tooltip" data-id="94"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikk-alpha">IKK alpha</a><br> <a target="_blank" href="/target/ikk-beta">IKK beta</a><br> <a target="_blank" href="/target/ikk-gamma">IKK gamma</a><br> <a target="_blank" href="/target/ikk-epsilon">IKK epsilon</a><br> <a target="_blank" href="/search?keywords=ikk*">All IKK Products</a><br> </div> </div> <div id="el95_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray95 pw-gray" style="top:659px;left:242px;"> </div> <div id="el95_off" data-id="95" data-set="IkappaB51" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off95" style="top:659px;left:242px;"> </div> <div id="el95_ct" class="pw-tooltip" data-id="95"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikb-alpha">IkB-alpha</a><br> <a target="_blank" href="/target/ikb-beta">IkB-beta</a><br> <a target="_blank" href="/target/ikb-epsilon">IkB-epsilon</a><br> </div> </div> <div id="el96_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray96 pw-gray" style="top:664px;left:260px;"> I kappa B </div> <div id="el96_off" data-id="96" data-set="IkappaB51" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off96" style="top:664px;left:260px;"> I kappa B</div> <div id="el96_ct" class="pw-tooltip" data-id="96"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikb-alpha">IkB-alpha</a><br> <a target="_blank" href="/target/ikb-beta">IkB-beta</a><br> <a target="_blank" href="/target/ikb-epsilon">IkB-epsilon</a><br> </div> </div> <div id="el97_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray97 pw-gray" style="top:622px;left:322px;"> </div> <div id="el97_off" data-id="97" data-set="IkappaB52" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off97" style="top:622px;left:322px;"> </div> <div id="el97_ct" class="pw-tooltip" data-id="97"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikb-alpha">IkB-alpha</a><br> <a target="_blank" href="/target/ikb-beta">IkB-beta</a><br> <a target="_blank" href="/target/ikb-epsilon">IkB-epsilon</a><br> </div> </div> <div id="el98_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray98 pw-gray" style="top:629px;left:287px;"> I kappa B </div> <div id="el98_off" data-id="98" data-set="IkappaB52" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off98" style="top:629px;left:287px;"> I kappa B</div> <div id="el98_ct" class="pw-tooltip" data-id="98"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ikb-alpha">IkB-alpha</a><br> <a target="_blank" href="/target/ikb-beta">IkB-beta</a><br> <a target="_blank" href="/target/ikb-epsilon">IkB-epsilon</a><br> </div> </div> <div id="el99_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray99 pw-gray" style="top:621px;left:333px;"> </div> <div id="el99_off" data-id="99" data-set="Proteasome53" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off99" style="top:621px;left:333px;"> </div> <div id="el99_ct" class="pw-tooltip" data-id="99"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/26s-proteasome">26S Proteasome</a><br> <a target="_blank" href="/target/19s-proteasome">19S Proteasome</a><br> <a target="_blank" href="/target/20s-proteasome">20S Proteasome</a><br> <a target="_blank" href="/target/proteasome-inhibitors">Proteasome Inhibitors</a><br> <a target="_blank" href="/target/proteasome-substrates">Proteasome Substrates</a><br> </div> </div> <div id="el100_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray100 pw-gray" style="top:612px;left:330px;"> Proteasome </div> <div id="el100_off" data-id="100" data-set="Proteasome53" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off100" style="top:612px;left:330px;"> Proteasome</div> <div id="el100_ct" class="pw-tooltip" data-id="100"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/26s-proteasome">26S Proteasome</a><br> <a target="_blank" href="/target/19s-proteasome">19S Proteasome</a><br> <a target="_blank" href="/target/20s-proteasome">20S Proteasome</a><br> <a target="_blank" href="/target/proteasome-inhibitors">Proteasome Inhibitors</a><br> <a target="_blank" href="/target/proteasome-substrates">Proteasome Substrates</a><br> </div> </div> <div id="el101_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray101 pw-gray" style="top:671px;left:234px;"> </div> <div id="el101_off" data-id="101" data-set="NF-kappaB54" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off101" style="top:671px;left:234px;"> </div> <div id="el101_ct" class="pw-tooltip" data-id="101"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb1">NFkB1</a><br> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> <a target="_blank" href="/target/rela-nfkb-p65">RelA/NFkB p65</a><br> <a target="_blank" href="/target/relb">RelB</a><br> <a target="_blank" href="/target/c-rel">c-Rel</a><br> </div> </div> <div id="el102_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray102 pw-gray" style="top:677px;left:222px;"> NF-kappa B </div> <div id="el102_off" data-id="102" data-set="NF-kappaB54" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off102" style="top:677px;left:222px;"> NF-kappa B</div> <div id="el102_ct" class="pw-tooltip" data-id="102"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb1">NFkB1</a><br> <a target="_blank" href="/target/nfkb2">NFkB2</a><br> <a target="_blank" href="/target/rela-nfkb-p65">RelA/NFkB p65</a><br> <a target="_blank" href="/target/relb">RelB</a><br> <a target="_blank" href="/target/c-rel">c-Rel</a><br> </div> </div> <div id="el103_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray103 pw-gray" style="top:919px;left:368px;"> </div> <div id="el103_off" data-id="103" data-set="NF-kappaBp5055" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off103" style="top:919px;left:368px;"> </div> <div id="el103_ct" class="pw-tooltip" data-id="103"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb1">NFkB1</a><br> </div> </div> <div id="el104_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray104 pw-gray" style="top:900px;left:357px;"> NF-kappa B p50 </div> <div id="el104_off" data-id="104" data-set="NF-kappaBp5055" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off104" style="top:900px;left:357px;"> NF-kappa B p50</div> <div id="el104_ct" class="pw-tooltip" data-id="104"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfkb1">NFkB1</a><br> </div> </div> <div id="el105_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray105 pw-gray" style="top:918px;left:381px;"> </div> <div id="el105_off" data-id="105" data-set="Rel56" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off105" style="top:918px;left:381px;"> </div> <div id="el105_ct" class="pw-tooltip" data-id="105"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> <a target="_blank" href="/target/c-rel">c-Rel</a><br> </div> </div> <div id="el106_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray106 pw-gray" style="top:924.9999694824219px;left:393px;"> Rel </div> <div id="el106_off" data-id="106" data-set="Rel56" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off106" style="top:924.9999694824219px;left:393px;"> Rel</div> <div id="el106_ct" class="pw-tooltip" data-id="106"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/relb">RelB</a><br> <a target="_blank" href="/target/c-rel">c-Rel</a><br> </div> </div> <div id="el107_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray107 pw-gray" style="top:692px;left:380px;"> </div> <div id="el107_off" data-id="107" data-set="p3857" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off107" style="top:692px;left:380px;"> </div> <div id="el107_ct" class="pw-tooltip" data-id="107"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/p38">p38</a><br> <a target="_blank" href="/target/p38 alpha">p38 alpha</a><br> <a target="_blank" href="/target/p38 beta">p38 beta</a><br> <a target="_blank" href="/target/p38 gamma">p38 gamma</a><br> <a target="_blank" href="/target/p38 delta">p38 delta</a><br> <a target="_blank" href="/search?keywords=p38">All p38 Products</a><br> </div> </div> <div id="el108_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray108 pw-gray" style="top:700px;left:382px;"> p38 </div> <div id="el108_off" data-id="108" data-set="p3857" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off108" style="top:700px;left:382px;"> p38</div> <div id="el108_ct" class="pw-tooltip" data-id="108"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/p38">p38</a><br> <a target="_blank" href="/target/p38 alpha">p38 alpha</a><br> <a target="_blank" href="/target/p38 beta">p38 beta</a><br> <a target="_blank" href="/target/p38 gamma">p38 gamma</a><br> <a target="_blank" href="/target/p38 delta">p38 delta</a><br> <a target="_blank" href="/search?keywords=p38">All p38 Products</a><br> </div> </div> <div id="el109_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray109 pw-gray" style="top:703px;left:418px;"> </div> <div id="el109_off" data-id="109" data-set="JNK58" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off109" style="top:703px;left:418px;"> </div> <div id="el109_ct" class="pw-tooltip" data-id="109"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/jnk">JNK</a><br> <a target="_blank" href="/target/jnk1/JNK2">JNK1/JNK2</a><br> <a target="_blank" href="/target/jnk1">JNK1</a><br> <a target="_blank" href="/target/jnk2">JNK2</a><br> <a target="_blank" href="/target/jnk3">JNK3</a><br> <a target="_blank" href="/search?keywords=jnk">All JNK Products</a><br> </div> </div> <div id="el110_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray110 pw-gray" style="top:711px;left:421px;"> JNK </div> <div id="el110_off" data-id="110" data-set="JNK58" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off110" style="top:711px;left:421px;"> JNK</div> <div id="el110_ct" class="pw-tooltip" data-id="110"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/jnk">JNK</a><br> <a target="_blank" href="/target/jnk1/JNK2">JNK1/JNK2</a><br> <a target="_blank" href="/target/jnk1">JNK1</a><br> <a target="_blank" href="/target/jnk2">JNK2</a><br> <a target="_blank" href="/target/jnk3">JNK3</a><br> <a target="_blank" href="/search?keywords=jnk">All JNK Products</a><br> </div> </div> <div id="el111_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray111 pw-gray" style="top:692px;left:460px;"> </div> <div id="el111_off" data-id="111" data-set="ERK1259" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off111" style="top:692px;left:460px;"> </div> <div id="el111_ct" class="pw-tooltip" data-id="111"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/erk1-erk2">ERK1/ERK2</a><br> <a target="_blank" href="/target/erk1">ERK1</a><br> <a target="_blank" href="/target/erk2">ERK2</a><br> </div> </div> <div id="el112_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray112 pw-gray" style="top:700px;left:456px;"> ERK1/2 </div> <div id="el112_off" data-id="112" data-set="ERK1259" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off112" style="top:700px;left:456px;"> ERK1/2</div> <div id="el112_ct" class="pw-tooltip" data-id="112"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/erk1-erk2">ERK1/ERK2</a><br> <a target="_blank" href="/target/erk1">ERK1</a><br> <a target="_blank" href="/target/erk2">ERK2</a><br> </div> </div> <div id="el113_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray113 pw-gray" style="top:829px;left:400px;"> </div> <div id="el113_off" data-id="113" data-set="AP-160" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off113" style="top:829px;left:400px;"> </div> <div id="el113_ct" class="pw-tooltip" data-id="113"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atf2">ATF2</a><br> <a target="_blank" href="/target/c-fos">c-Fos</a><br> <a target="_blank" href="/target/fosb-g0s3">FosB/G0S3</a><br> <a target="_blank" href="/target/fra-1">FRA-1</a><br> <a target="_blank" href="/target/c-jun">c-Jun</a><br> <a target="_blank" href="/target/junb">JunB</a><br> <a target="_blank" href="/target/jund">JunD</a><br> </div> </div> <div id="el114_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray114 pw-gray" style="top:822px;left:407px;"> AP-1 </div> <div id="el114_off" data-id="114" data-set="AP-160" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off114" style="top:822px;left:407px;"> AP-1</div> <div id="el114_ct" class="pw-tooltip" data-id="114"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atf2">ATF2</a><br> <a target="_blank" href="/target/c-fos">c-Fos</a><br> <a target="_blank" href="/target/fosb-g0s3">FosB/G0S3</a><br> <a target="_blank" href="/target/fra-1">FRA-1</a><br> <a target="_blank" href="/target/c-jun">c-Jun</a><br> <a target="_blank" href="/target/junb">JunB</a><br> <a target="_blank" href="/target/jund">JunD</a><br> </div> </div> <div id="el115_gry" class="clr_all clr_bdca2 pw-sprite el-gray115 pw-gray" style="top:435.9999694824219px;left:512px;"> </div> <div id="el115_off" data-id="115" data-set="IP3115" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off115" style="top:435.9999694824219px;left:512px;"> </div> <div id="el115_ct" class="pw-tooltip" data-id="115"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=IP3">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el116_gry" class="clr_all clr_bdca2 pw-label el-gray116 pw-gray" style="top:443.9999694824219px;left:518px;"> IP<sub>3</sub> </div> <div id="el116_off" data-id="116" data-set="IP3115" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off116" style="top:443.9999694824219px;left:518px;"> IP<sub>3</sub></div> <div id="el116_ct" class="pw-tooltip" data-id="116"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=IP3">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el117_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle clr_bdca2 pw-label el-gray117 pw-gray" style="top:806px;left:582px;"> IP<sub>3</sub> Receptor </div> <div id="el117_off" data-id="117" data-set="IP3Receptor61" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle clr_bdca2 pw-label el-off117" style="top:806px;left:582px;"> IP<sub>3</sub> Receptor</div> <div id="el117_ct" class="pw-tooltip" data-id="117"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/ip3-receptor-inhibitors">IP3 Receptor Inhibitors</a><br> </div> </div> <div id="el118_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray118 pw-gray" style="top:666px;left:568px;"> </div> <div id="el118_off" data-id="118" data-set="Calmodulin63" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off118" style="top:666px;left:568px;"> </div> <div id="el118_ct" class="pw-tooltip" data-id="118"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calmodulin-1">Calmodulin 1</a><br> </div> </div> <div id="el119_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray119 pw-gray" style="top:690px;left:548px;"> Calmodulin </div> <div id="el119_off" data-id="119" data-set="Calmodulin63" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off119" style="top:690px;left:548px;"> Calmodulin</div> <div id="el119_ct" class="pw-tooltip" data-id="119"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calmodulin-1">Calmodulin 1</a><br> </div> </div> <div id="el120_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray120 pw-gray" style="top:658px;left:557px;"> </div> <div id="el120_off" data-id="120" data-set="CalcineurinPhosphatase64" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off120" style="top:658px;left:557px;"> </div> <div id="el120_ct" class="pw-tooltip" data-id="120"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calcineurin">Calcineurin</a><br> <a target="_blank" href="/target/calcineurin A">Calcineurin A</a><br> <a target="_blank" href="/target/calcineurin B">Calcineurin B</a><br> </div> </div> <div id="el121_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label pw-center el-gray121 pw-gray" style="top:632.9999694824219px;left:527px;"> Calcineurin<br>Phosphatase </div> <div id="el121_off" data-id="121" data-set="CalcineurinPhosphatase64" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label pw-center el-off121" style="top:632.9999694824219px;left:527px;"> Calcineurin<br>Phosphatase</div> <div id="el121_ct" class="pw-tooltip" data-id="121"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calcineurin">Calcineurin</a><br> <a target="_blank" href="/target/calcineurin A">Calcineurin A</a><br> <a target="_blank" href="/target/calcineurin B">Calcineurin B</a><br> </div> </div> <div id="el122_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray122 pw-gray" style="top:719px;left:509px;"> </div> <div id="el122_off" data-id="122" data-set="NFATC65" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off122" style="top:719px;left:509px;"> </div> <div id="el122_ct" class="pw-tooltip" data-id="122"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfatc1">NFATC1</a><br> <a target="_blank" href="/target/nfatc2">NFATC2</a><br> <a target="_blank" href="/target/nfatc3">NFATC3</a><br> <a target="_blank" href="/search?keywords=NFATC*">All NFATC Products</a><br> </div> </div> <div id="el123_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray123 pw-gray" style="top:728px;left:522px;"> NFATC </div> <div id="el123_off" data-id="123" data-set="NFATC65" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off123" style="top:728px;left:522px;"> NFATC</div> <div id="el123_ct" class="pw-tooltip" data-id="123"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfatc1">NFATC1</a><br> <a target="_blank" href="/target/nfatc2">NFATC2</a><br> <a target="_blank" href="/target/nfatc3">NFATC3</a><br> <a target="_blank" href="/search?keywords=NFATC*">All NFATC Products</a><br> </div> </div> <div id="el124_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-gray124 pw-gray" style="top:909px;left:581px;"> </div> <div id="el124_off" data-id="124" data-set="NFATC66" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-sprite el-off124" style="top:909px;left:581px;"> </div> <div id="el124_ct" class="pw-tooltip" data-id="124"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfatc1">NFATC1</a><br> <a target="_blank" href="/target/nfatc2">NFATC2</a><br> <a target="_blank" href="/target/nfatc3">NFATC3</a><br> <a target="_blank" href="/search?keywords=NFATC*">All NFATC Products</a><br> </div> </div> <div id="el125_gry" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-gray125 pw-gray" style="top:916.9999694824219px;left:560px;"> NFATC </div> <div id="el125_off" data-id="125" data-set="NFATC66" data-type="No Products Click" class="clr_all clr_dectin1 clr_dectin2 clr_mincle pw-label el-off125" style="top:916.9999694824219px;left:560px;"> NFATC</div> <div id="el125_ct" class="pw-tooltip" data-id="125"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/nfatc1">NFATC1</a><br> <a target="_blank" href="/target/nfatc2">NFATC2</a><br> <a target="_blank" href="/target/nfatc3">NFATC3</a><br> <a target="_blank" href="/search?keywords=NFATC*">All NFATC Products</a><br> </div> </div> <div id="el126_gry" class="clr_all clr_bdca2 pw-sprite el-gray126 pw-gray" style="top:17px;left:477px;"> </div> <div id="el126_off" data-id="126" data-set="BDCA-267" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off126" style="top:17px;left:477px;"> </div> <div id="el126_ct" class="pw-tooltip" data-id="126"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/CLEC4C/BDCA-2</a><br> </div> </div> <div id="el127_gry" class="clr_all clr_bdca2 pw-label el-gray127 pw-gray" style="top:2px;left:473px;"> BDCA-2 </div> <div id="el127_off" data-id="127" data-set="BDCA-267" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off127" style="top:2px;left:473px;"> BDCA-2</div> <div id="el127_ct" class="pw-tooltip" data-id="127"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dlec-clec4c-bdca-2">DLEC/CLEC4C/BDCA-2</a><br> </div> </div> <div id="el128_gry" class="clr_all clr_bdca2 pw-sprite el-gray128 pw-gray" style="top:53px;left:487px;"> </div> <div id="el128_off" data-id="128" data-set="FcRgamma68" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off128" style="top:53px;left:487px;"> </div> <div id="el128_ct" class="pw-tooltip" data-id="128"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Fc%20receptor%20gamma-chain%20">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el129_gry" class="clr_all clr_bdca2 pw-label el-gray129 pw-gray" style="top:46px;left:497px;"> FcR gamma </div> <div id="el129_off" data-id="129" data-set="FcRgamma68" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off129" style="top:46px;left:497px;"> FcR gamma</div> <div id="el129_ct" class="pw-tooltip" data-id="129"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Fc%20receptor%20gamma-chain%20">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el130_gry" class="clr_all clr_bdca2 pw-sprite el-gray130 pw-gray" style="top:85px;left:512px;"> </div> <div id="el130_off" data-id="130" data-set="SYK69" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off130" style="top:85px;left:512px;"> </div> <div id="el130_ct" class="pw-tooltip" data-id="130"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el131_gry" class="clr_all clr_bdca2 pw-label el-gray131 pw-gray" style="top:93px;left:524px;"> SYK </div> <div id="el131_off" data-id="131" data-set="SYK69" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off131" style="top:93px;left:524px;"> SYK</div> <div id="el131_ct" class="pw-tooltip" data-id="131"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/syk">SYK</a><br> </div> </div> <div id="el132_gry" class="clr_all clr_bdca2 pw-sprite el-gray132 pw-gray" style="top:286px;left:465px;"> </div> <div id="el132_off" data-id="132" data-set="BLNK70" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off132" style="top:286px;left:465px;"> </div> <div id="el132_ct" class="pw-tooltip" data-id="132"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/blnk">BLNK</a><br> </div> </div> <div id="el133_gry" class="clr_all clr_bdca2 pw-label el-gray133 pw-gray" style="top:280.9999694824219px;left:464px;"> BLNK </div> <div id="el133_off" data-id="133" data-set="BLNK70" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off133" style="top:280.9999694824219px;left:464px;"> BLNK</div> <div id="el133_ct" class="pw-tooltip" data-id="133"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/blnk">BLNK</a><br> </div> </div> <div id="el134_gry" class="clr_all clr_bdca2 pw-sprite el-gray134 pw-gray" style="top:302px;left:447px;"> </div> <div id="el134_off" data-id="134" data-set="PLC-gamma271" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off134" style="top:302px;left:447px;"> </div> <div id="el134_ct" class="pw-tooltip" data-id="134"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/plc-gamma-2">PLC-gamma 2</a><br> </div> </div> <div id="el135_gry" class="clr_all clr_bdca2 pw-label el-gray135 pw-gray" style="top:309.9999694824219px;left:383px;"> PLC-gamma 2 </div> <div id="el135_off" data-id="135" data-set="PLC-gamma271" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off135" style="top:309.9999694824219px;left:383px;"> PLC-gamma 2</div> <div id="el135_ct" class="pw-tooltip" data-id="135"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/plc-gamma-2">PLC-gamma 2</a><br> </div> </div> <div id="el136_gry" class="clr_all clr_bdca2 pw-sprite el-gray136 pw-gray" style="top:303px;left:479px;"> </div> <div id="el136_off" data-id="136" data-set="BTK72" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off136" style="top:303px;left:479px;"> </div> <div id="el136_ct" class="pw-tooltip" data-id="136"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/btk">BTK</a><br> </div> </div> <div id="el137_gry" class="clr_all clr_bdca2 pw-label el-gray137 pw-gray" style="top:310.9999694824219px;left:493px;"> BTK </div> <div id="el137_off" data-id="137" data-set="BTK72" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off137" style="top:310.9999694824219px;left:493px;"> BTK</div> <div id="el137_ct" class="pw-tooltip" data-id="137"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/btk">BTK</a><br> </div> </div> <div id="el138_gry" class="clr_all clr_bdca2 pw-sprite el-gray138 pw-gray" style="top:557px;left:683px;"> </div> <div id="el138_off" data-id="138" data-set="Calmodulin73" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off138" style="top:557px;left:683px;"> </div> <div id="el138_ct" class="pw-tooltip" data-id="138"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calmodulin-1">Calmodulin 1</a><br> </div> </div> <div id="el139_gry" class="clr_all clr_bdca2 pw-label el-gray139 pw-gray" style="top:578px;left:666px;"> Calmodulin </div> <div id="el139_off" data-id="139" data-set="Calmodulin73" data-type="No Products Click" class="clr_all clr_bdca2 pw-label el-off139" style="top:578px;left:666px;"> Calmodulin</div> <div id="el139_ct" class="pw-tooltip" data-id="139"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calmodulin-1">Calmodulin 1</a><br> </div> </div> <div id="el140_gry" class="clr_all clr_bdca2 pw-sprite el-gray140 pw-gray" style="top:549.9999694824219px;left:671px;"> </div> <div id="el140_off" data-id="140" data-set="CalcineurinPhosphatase74" data-type="No Products Click" class="clr_all clr_bdca2 pw-sprite el-off140" style="top:549.9999694824219px;left:671px;"> </div> <div id="el140_ct" class="pw-tooltip" data-id="140"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calcineurin">Calcineurin</a><br> <a target="_blank" href="/target/calcineurin A">Calcineurin A</a><br> <a target="_blank" href="/target/calcineurin B">Calcineurin B</a><br> </div> </div> <div id="el141_gry" class="clr_all clr_bdca2 pw-label pw-center el-gray141 pw-gray" style="top:524.9999694824219px;left:644px;"> Calcineurin<br>Phosphatase </div> <div id="el141_off" data-id="141" data-set="CalcineurinPhosphatase74" data-type="No Products Click" class="clr_all clr_bdca2 pw-label pw-center el-off141" style="top:524.9999694824219px;left:644px;"> Calcineurin<br>Phosphatase</div> <div id="el141_ct" class="pw-tooltip" data-id="141"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/calcineurin">Calcineurin</a><br> <a target="_blank" href="/target/calcineurin A">Calcineurin A</a><br> <a target="_blank" href="/target/calcineurin B">Calcineurin B</a><br> </div> </div> <div id="el142_gry" class="clr_all clr_bdca2 clr_dcir pw-sprite el-gray142 pw-gray" style="top:399.9999694824219px;left:575px;"> </div> <div id="el142_off" data-id="142" data-set="MyD8875" data-type="No Products Click" class="clr_all clr_bdca2 clr_dcir pw-sprite el-off142" style="top:399.9999694824219px;left:575px;"> </div> <div id="el142_ct" class="pw-tooltip" data-id="142"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/myd88">MyD88</a><br> </div> </div> <div id="el143_gry" class="clr_all clr_bdca2 clr_dcir pw-label el-gray143 pw-gray" style="top:413.9999694824219px;left:541px;"> MyD88 </div> <div id="el143_off" data-id="143" data-set="MyD8875" data-type="No Products Click" class="clr_all clr_bdca2 clr_dcir pw-label el-off143" style="top:413.9999694824219px;left:541px;"> MyD88</div> <div id="el143_ct" class="pw-tooltip" data-id="143"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/myd88">MyD88</a><br> </div> </div> <div id="el144_gry" class="clr_all clr_bdca2 clr_dcir pw-sprite el-gray144 pw-gray" style="top:341.9999694824219px;left:579px;"> </div> <div id="el144_off" data-id="144" data-set="TLR976" data-type="No Products Click" class="clr_all clr_bdca2 clr_dcir pw-sprite el-off144" style="top:341.9999694824219px;left:579px;"> </div> <div id="el144_ct" class="pw-tooltip" data-id="144"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tlr9">TLR9</a><br> </div> </div> <div id="el145_gry" class="clr_all clr_bdca2 clr_dcir pw-label el-gray145 pw-gray" style="top:356.9999694824219px;left:580px;"> TLR9 </div> <div id="el145_off" data-id="145" data-set="TLR976" data-type="No Products Click" class="clr_all clr_bdca2 clr_dcir pw-label el-off145" style="top:356.9999694824219px;left:580px;"> TLR9</div> <div id="el145_ct" class="pw-tooltip" data-id="145"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tlr9">TLR9</a><br> </div> </div> <div id="el146_gry" class="clr_all clr_bdca2 clr_dcir pw-label2 el-gray146 pw-gray" style="top:328.9999694824219px;left:574px;"> Endosome </div> <div id="el146_off" data-id="146" data-set="Endosome" data-type="" class="clr_all clr_bdca2 clr_dcir pw-label2 el-off146" style="top:328.9999694824219px;left:574px;"> Endosome</div> <div id="el146_ct" class="pw-tooltip" data-id="146"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el147_gry" class="clr_all clr_dcir pw-sprite el-gray147 pw-gray" style="top:48px;left:584px;"> </div> <div id="el147_off" data-id="147" data-set="DCIR78" data-type="" class="clr_all clr_dcir pw-sprite el-off147" style="top:48px;left:584px;"> </div> <div id="el147_ct" class="pw-tooltip" data-id="147"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dcir-clec4a">DCIR/CLEC4A</a><br> </div> </div> <div id="el148_gry" class="clr_all clr_dcir pw-label el-gray148 pw-gray" style="top:38px;left:584px;"> DCIR </div> <div id="el148_off" data-id="148" data-set="DCIR78" data-type="No Products Click" class="clr_all clr_dcir pw-label el-off148" style="top:38px;left:584px;"> DCIR</div> <div id="el148_ct" class="pw-tooltip" data-id="148"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dcir-clec4a">DCIR/CLEC4A</a><br> </div> </div> <div id="el149_gry" class="clr_all clr_dcir pw-sprite el-gray149 pw-gray" style="top:110px;left:567px;"> </div> <div id="el149_off" data-id="149" data-set="SHP-1orSHP-279" data-type="No Products Click" class="clr_all clr_dcir pw-sprite el-off149" style="top:110px;left:567px;"> </div> <div id="el149_ct" class="pw-tooltip" data-id="149"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/shp-1">SHP-1</a><br> <a target="_blank" href="/target/shp-2">SHP-2</a><br> </div> </div> <div id="el150_gry" class="clr_all clr_dcir pw-label el-gray150 pw-gray" style="top:118px;left:578px;"> SHP-1 or<br>SHP-2 </div> <div id="el150_off" data-id="150" data-set="SHP-1orSHP-279" data-type="No Products Click" class="clr_all clr_dcir pw-label el-off150" style="top:118px;left:578px;"> SHP-1 or<br>SHP-2</div> <div id="el150_ct" class="pw-tooltip" data-id="150"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/shp-1">SHP-1</a><br> <a target="_blank" href="/target/shp-2">SHP-2</a><br> </div> </div> <div id="el151_gry" class="clr_all clr_dcir pw-sprite el-gray151 pw-gray" style="top:252px;left:616px;"> </div> <div id="el151_off" data-id="151" data-set="DCIR80" data-type="No Products Click" class="clr_all clr_dcir pw-sprite el-off151" style="top:252px;left:616px;"> </div> <div id="el151_ct" class="pw-tooltip" data-id="151"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dcir-clec4a">DCIR/CLEC4A</a><br> </div> </div> <div id="el152_gry" class="clr_all clr_dcir pw-label el-gray152 pw-gray" style="top:299px;left:640px;"> DCIR </div> <div id="el152_off" data-id="152" data-set="DCIR80" data-type="No Products Click" class="clr_all clr_dcir pw-label el-off152" style="top:299px;left:640px;"> DCIR</div> <div id="el152_ct" class="pw-tooltip" data-id="152"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/dcir-clec4a">DCIR/CLEC4A</a><br> </div> </div> <div id="el153_gry" class="clr_all clr_dcir pw-sprite el-gray153 pw-gray" style="top:258px;left:631px;"> </div> <div id="el153_off" data-id="153" data-set="SHP-1orSHP-281" data-type="No Products Click" class="clr_all clr_dcir pw-sprite el-off153" style="top:258px;left:631px;"> </div> <div id="el153_ct" class="pw-tooltip" data-id="153"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/shp-1">SHP-1</a><br> <a target="_blank" href="/target/shp-2">SHP-2</a><br> </div> </div> <div id="el154_gry" class="clr_all clr_dcir pw-label el-gray154 pw-gray" style="top:249px;left:643px;"> SHP-1 or<br>SHP-2 </div> <div id="el154_off" data-id="154" data-set="SHP-1orSHP-281" data-type="No Products Click" class="clr_all clr_dcir pw-label el-off154" style="top:249px;left:643px;"> SHP-1 or<br>SHP-2</div> <div id="el154_ct" class="pw-tooltip" data-id="154"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/shp-1">SHP-1</a><br> <a target="_blank" href="/target/shp-2">SHP-2</a><br> </div> </div> <div id="el155_gry" class="clr_all clr_dcir pw-sprite el-gray155 pw-gray" style="top:335px;left:628px;"> </div> <div id="el155_off" data-id="155" data-set="TLR882" data-type="No Products Click" class="clr_all clr_dcir pw-sprite el-off155" style="top:335px;left:628px;"> </div> <div id="el155_ct" class="pw-tooltip" data-id="155"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tlr8">TLR8</a><br> </div> </div> <div id="el156_gry" class="clr_all clr_dcir pw-label el-gray156 pw-gray" style="top:347.9999694824219px;left:652px;"> TLR8 </div> <div id="el156_off" data-id="156" data-set="TLR882" data-type="No Products Click" class="clr_all clr_dcir pw-label el-off156" style="top:347.9999694824219px;left:652px;"> TLR8</div> <div id="el156_ct" class="pw-tooltip" data-id="156"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/tlr8">TLR8</a><br> </div> </div> <div id="el157_gry" class="clr_all clr_dcir pw-sprite el-gray157 pw-gray" style="top:391.9999694824219px;left:658px;"> </div> <div id="el157_off" data-id="157" data-set="MyD8883" data-type="No Products Click" class="clr_all clr_dcir pw-sprite el-off157" style="top:391.9999694824219px;left:658px;"> </div> <div id="el157_ct" class="pw-tooltip" data-id="157"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/myd88">MyD88</a><br> </div> </div> <div id="el158_gry" class="clr_all clr_dcir pw-label el-gray158 pw-gray" style="top:420.9999694824219px;left:654px;"> MyD88 </div> <div id="el158_off" data-id="158" data-set="MyD8883" data-type="No Products Click" class="clr_all clr_dcir pw-label el-off158" style="top:420.9999694824219px;left:654px;"> MyD88</div> <div id="el158_ct" class="pw-tooltip" data-id="158"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/myd88">MyD88</a><br> </div> </div> <div id="el159_gry" class="clr_all clr_micl pw-sprite el-gray159 pw-gray" style="top:66px;left:660px;"> </div> <div id="el159_off" data-id="159" data-set="MICLCLEC12A84" data-type="No Products Click" class="clr_all clr_micl pw-sprite el-off159" style="top:66px;left:660px;"> </div> <div id="el159_ct" class="pw-tooltip" data-id="159"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/micl-clec12a">MICL/CLEC12A</a><br> </div> </div> <div id="el160_gry" class="clr_all clr_micl pw-label el-gray160 pw-gray" style="top:58px;left:643px;"> MICL/CLEC12A </div> <div id="el160_off" data-id="160" 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pw-gray" style="top:128px;left:689px;"> SHP-1 or<br>SHP-2 </div> <div id="el162_off" data-id="162" data-set="SHP-1orSHP-285" data-type="No Products Click" class="clr_all clr_micl pw-label el-off162" style="top:128px;left:689px;"> SHP-1 or<br>SHP-2</div> <div id="el162_ct" class="pw-tooltip" data-id="162"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/shp-1">SHP-1</a><br> <a target="_blank" href="/target/shp-2">SHP-2</a><br> </div> </div> <div id="el163_gry" class="clr_all clr_micl pw-sprite el-gray163 pw-gray" style="top:166px;left:671px;"> </div> <div id="el163_off" data-id="163" data-set="ERK86" data-type="No Products Click" class="clr_all clr_micl pw-sprite el-off163" style="top:166px;left:671px;"> </div> <div id="el163_ct" class="pw-tooltip" data-id="163"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/erk1-erk2">ERK1/ERK2</a><br> <a target="_blank" href="/target/erk1">ERK1</a><br> <a target="_blank" href="/target/erk2">ERK2</a><br> </div> </div> <div id="el164_gry" class="clr_all clr_micl pw-label el-gray164 pw-gray" style="top:174px;left:675px;"> ERK </div> <div id="el164_off" data-id="164" data-set="ERK86" data-type="No Products Click" class="clr_all clr_micl pw-label el-off164" style="top:174px;left:675px;"> ERK</div> <div id="el164_ct" class="pw-tooltip" data-id="164"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/erk1-erk2">ERK1/ERK2</a><br> <a target="_blank" href="/target/erk1">ERK1</a><br> <a target="_blank" href="/target/erk2">ERK2</a><br> </div> </div> <div id="el165_gry" class="clr_all clr_micl pw-label2 el-gray165 pw-gray" style="top:208px;left:648px;"> TLR Signaling </div> <div id="el165_off" data-id="165" data-set="TLRSignaling" data-type="" class="clr_all clr_micl pw-label2 el-off165" style="top:208px;left:648px;"> TLR Signaling</div> <div id="el165_ct" class="pw-tooltip" data-id="165"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el166_off" data-id="166" data-set="table" data-type="" class="clr_bdca2 pw-label2 pw-none el-off166" style="top:40px;left:280px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:180px"><tr><th> BDCA-2/CLEC4C</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> Mannose, fucose </td></tr><tr><td> <strong>Source(s)</strong><br> Unknown </td></tr></table></div> <div id="el166_ct" class="pw-tooltip" data-id="166"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el167_off" data-id="167" data-set="table" data-type="" class="clr_dcir pw-label2 pw-none el-off167" style="top:40px;left:380px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:180px"><tr><th> DCIR/CLEC4A</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> Mannose, fucose </td></tr><tr><td> <strong>Source(s)</strong><br> HIV </td></tr></table></div> <div id="el167_ct" class="pw-tooltip" data-id="167"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el168_off" data-id="168" data-set="table" data-type="" class="clr_dcsign pw-label2 pw-none el-off168" style="top:40px;left:200px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:260px"><tr><th> DC-SIGN/CD209</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> High mannose, fucose, and Salp15, a protein produced by the salivary glands of Ixodes scapularis ticks that promotes the pathogenesis of Lyme disease </td></tr><tr><td> <strong>Source(s)</strong><br> Candida albicans, cytomegalovirus, dengue virus, filoviruses, HIV, Leishmania spp., measles virus, Mycobacterium spp., SARS, Lewis antigens in Helicobacter pylori and Schistosoma mansoni </td></tr></table></div> <div id="el168_ct" class="pw-tooltip" data-id="168"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el169_off" data-id="169" data-set="table" data-type="" class="clr_dectin1 pw-label2 pw-none el-off169" style="top:20px;left:310px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:280px"><tr><th> Dectin-1/CLEC7A</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> beta-1,3-linked glucans </td></tr><tr><td> <strong>Source(s)</strong><br> Mycobacteria and fungi including Candida spp., Aspergillus spp., Coccidioides spp., and Pneumocystis spp. </td></tr></table></div> <div id="el169_ct" class="pw-tooltip" data-id="169"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el170_off" data-id="170" data-set="table" data-type="" class="clr_dectin2 pw-label2 pw-none el-off170" style="top:40px;left:20px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:320px"><tr><th> Dectin-2/CLEC6A</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> High mannose, alpha-mannans </td></tr><tr><td> <strong>Source(s)</strong><br> Mycobacterium tuberculosis, Schistosoma mansoni, house dust mite allergens, and fungi including Candida albicans, Cryptococcus neoformans, Histoplasma capsulatum, Microsporum audouinii, Paracoccidioides brasiliensis, Saccharomyces cerevisiae, Trichophyton rubrum </td></tr></table></div> <div id="el170_ct" class="pw-tooltip" data-id="170"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el171_off" data-id="171" data-set="table" data-type="" class="clr_mincle pw-label2 pw-none el-off171" style="top:10px;left:400px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:320px"><tr><th> Mincle/CLEC4E</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> alpha-mannose, glycolipids including the mycobacterial cord factor trehalose 6,6'-dimycolate (TDM), and endogenous SAP130, a nuclear protein released by necrotic cells </td></tr><tr><td> <strong>Source(s)</strong><br> Mycobacterium tuberculosis, dead cells, and fungi including Candida albicans, Malassezia spp., and Fonsecaea pedrosoi </td></tr></table></div> <div id="el171_ct" class="pw-tooltip" data-id="171"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el172_off" data-id="172" data-set="table" data-type="" class="clr_micl pw-label2 pw-none el-off172" style="top:40px;left:440px;"> <table class=pw_table cellpadding=0 cellspacing=0 style="width:180px"><tr><th> MICL/CLEC12A</th></tr><tr><td> <strong>Select Ligand(s)</strong></td></tr><tr><td> Unknown </td></tr><tr><td> <strong>Source(s)</strong><br> Unknown </td></tr></table></div> <div id="el172_ct" class="pw-tooltip" data-id="172"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> </div> <div id="pw-img"> <img id="cont-img" src="https://resources.rndsystems.com/images/Pathways/pathway-images/clr_all.png" alt="Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways" style="height:1064px"> </div> </div> <div id="pathway-description"><h2>Overview of Pathogen- or Damage-activated C-type Lectin Receptor Signaling Pathways</h2><p><p>C-type lectin receptors (CLRs) are a large family of soluble and transmembrane proteins that contain one or more distinct protein folds known as C-type lectin-like domains (CTLD). A small subset of these proteins has been categorized as pattern recognition receptors due to the fact that they are activated by specific pathogen- or damage-associated molecules and induce signaling pathways that regulate the immune response. With the exception of DC-SIGN, most CLRs that function in this way belong to either the Dectin-1 (Dectin-1, CLEC-1, CLEC-2, CLEC9a, CLEC12B, LOX-1/OLR1, and MICL/CLEC12A) or Dectin-2 (Dectin-2, BDCA-2, CLEC4D/CLECSF8, DCAR, DCIR, and Mincle) subfamilies. These receptors are type II transmembrane proteins that are highly expressed on monocytes, macrophages, and/or dendritic cells and are variably expressed by a number of other cell types. They recognize carbohydrates such as glucans, fucose, and high mannose structures present in mycobacteria, viruses, and fungi. In addition, some CLRs are activated by host-derived damage signals.</p> <p>Dectin-1, Dectin-2, and Mincle are three well-characterized pathogen recognition CLRs that induce canonical NF-kappa B signaling, MAPK signaling, and NFAT-dependent transcription. Activation of these pathways occurs following phosphorylation of either the cytoplasmic hemi-immunoreceptor tyrosine-based activation motif (hemITAM) domain in Dectin-1 or the ITAM-containing FcR gamma adaptor protein that associates with Dectin-2 and Mincle. These phosphorylation events, mediated primarily by Src family kinases, create a docking site for spleen tyrosine kinase (SYK), which triggers SYK-mediated phagocytosis, the generation of reactive oxygen species (ROS), and activation of PLC-gamma 2. PLC-gamma 2 catalyzes the hydrolysis of phosphatidylinositol 4, 5-bisphosphate (PIP2), leading to an IP<sub>3</sub>-dependent Ca<sup>2+</sup> flux and activation of PKC delta by diacylglycerol (DAG). Signaling through PKC delta stimulates a multiprotein complex consisting of CARD9, Bcl-10, and MALT1, which activates I kappa b kinase (IKK) and multiple mitogen-activated protein kinases (MAPKs) including p38, JNK, and ERK1/2. IKK subsequently phosphorylates I kappa B and promotes the nuclear translocation of NF-kappa B, while p38, JNK, and ERK1/2 phosphorylate and activate AP-1. In addition to activating the canonical NF-kappa B signaling pathway, Dectin-1 signaling also regulates NF-kappa B activity through the NIK-dependent, non-canonical NF-kappa B pathway and by Raf-1-mediated phosphorylation. Raf-1-induced phosphorylation of NF-kappa B leads to acetylation of its p65 subunit by CREB binding protein (CBP) and p300, which enhances its transcriptional activity. As a result of their abilities to regulate signaling pathways that promote the activities of NF-kappa B, AP-1, and C/EBP, Dectin-1, Dectin-2, and Mincle control the expression of a wide range of cytokines that direct the innate and adaptive immune response.</p/> <p>Similar to Dectin-1, DC-SIGN/CD209 signaling has been shown to activate Raf-1-mediated NF-kappa B phosphorylation, but how this receptor initiates intracellular signaling is not clear. Both Src family kinases and p21-activated kinases (PAKs) phosphorylate Raf-1 downstream of DC-SIGN/CD209, but the intracellular signaling molecules that sense DC-SIGN activation and promote Raf-1 phosphorylation by Src and PAKs are not known. DC-SIGN/CD209 signaling is further complicated by the observation that this receptor can activate different signaling pathways depending on the pathogen that it detects and this can alter the outcome of the immune response. Both DC-SIGN/CD209 and BDCA-2 modulate Toll-like receptor (TLR) signaling, although this seems to occur through two different pathways as BDCA-2 has not been shown to signal through Raf-1. Instead, BDCA-2 associates with FcR gamma and recruits SYK, which then signals through a complex consisting of PLC-gamma 2, B cell linker (BLNK), and Bruton’s tyrosine kinase (BTK) to promote Ca<sup>2+</sup> mobilization. Mobilization of Ca<sup>2+</sup> may negatively regulate TLR signaling through activation of Calcineurin phosphatase, which inhibits the TLR adaptor protein MyD88.</p> <p>In contrast to the ITAM-containing receptors, DCIR/CLEC4A, MICL/CLEC12A, and CLEC12B contain an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic domains. Following activation, this domain in DCIR/CLEC4A or MICL/CLEC12A recruits the SHP-1 or SHP-2 phosphatases and inhibits TLR8 or TLR9 signaling through an undefined mechanism. Less is known about the ligand specificity and downstream signaling pathways activated by other members of the Dectin-1 and Dectin-2 subfamilies. Since these receptors are important for both anti-fungal immunity and for the recognition of endogenous ligands, further investigation of the signaling pathways and the biological effects that they promote is necessary.<br /> <p>To learn more, please visit our <a href="/research-area/c--type-lectin-receptors">C-type Lectin Receptors Research Area</a>.</p></p></div> <div id="print-copy-form" class="accordion-wrapper"> <h3 class="builder-header builder-bead-type ui-accordion-header ui-helper-reset ui-state-default ui-corner-all ui-accordion-icons" data-toggle="collapse" data-target="#collapsePathwayRequest" aria-expanded="false" id="pathwayRequestAccordionHeader"> <span class="ui-accordion-header-icon" id="accordionArrow"></span> Get Print Copy of this Pathway </h3> <div class="collapse" id="collapsePathwayRequest"> <div id="pathwayRequestWebformWrapper"> <form class="webform-client-form webform-client-form-27981" 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maxlength="128" /></div><div class="form-item webform-component webform-component-textfield webform-component--city form-group form-item form-item-submitted-city form-type-textfield form-group"> <label class="control-label" for="edit-submitted-city">City <span class="form-required" title="This field is required.">*</span></label> <input required="required" class="form-control form-text required" type="text" id="edit-submitted-city" name="submitted[city]" value="" size="60" maxlength="128" /></div><div class="form-item webform-component webform-component-select webform-component--state form-group form-item form-item-submitted-state form-type-select form-group"> <label class="control-label" for="edit-submitted-state">State</label> <div class="select_wrapper"><select class="form-control form-select" id="edit-submitted-state" name="submitted[state]"><option value="" selected="selected">- None -</option><option value="AL">Alabama</option><option value="AK">Alaska</option><option value="AS">American Samoa</option><option value="AZ">Arizona</option><option value="AR">Arkansas</option><option value="CA">California</option><option value="CO">Colorado</option><option value="CT">Connecticut</option><option value="DE">Delaware</option><option value="DC">District of Columbia</option><option value="FL">Florida</option><option value="GA">Georgia</option><option value="GU">Guam</option><option value="HI">Hawaii</option><option value="ID">Idaho</option><option value="IL">Illinois</option><option value="IN">Indiana</option><option value="IA">Iowa</option><option value="KS">Kansas</option><option value="KY">Kentucky</option><option value="LA">Louisiana</option><option value="ME">Maine</option><option value="MH">Marshall Islands</option><option value="MD">Maryland</option><option value="MA">Massachusetts</option><option value="MI">Michigan</option><option value="MN">Minnesota</option><option value="MS">Mississippi</option><option value="MO">Missouri</option><option 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