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Navigation of magnetic microrobots with different user interaction levels

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Their application in lab-on-a-chip systems, such as micromanipulation and in vitro cell sorting, is expected to steeply increase. However, the actuation, powering and control of microrobots are challenges that still need concrete solutions. Magnetic fields generally enable wireless navigation of microrobots, but proper control architectures and magnetic navigation systems are needed, depending on the specific task and on the level of interaction required to the user. Here we present a magnetic navigation platform intended for lab-on-a-chip applications and we address its usability with different levels of human involvement by using two control architectures: teleoperated and autonomous. We perform an experimental analysis to demonstrate that both architectures, enrolling different levels of interaction by the user, lead to reliable execution of the microrobotic task. First, we validate the open-loop response of the microrobotic system, and second, we evaluate the performance of the system by testing both control architectures with a standard mobility task. The results show that users can teleoperate the microrobot with 100% success rate, in 14.4 卤 1.9s with a normalized spatial mean error of 0.60 卤 0.13. Moreover, results show a fast decaying learning curve for the users involved in the study. Compared to this, when the navigation task is performed by the autonomous control, 100% success rate, a time of 8.0 卤 0.5s and a normalized spatial mean error of 0.50 卤 0.05 are obtained. Finally, we quantitatively demonstrate how both control methodologies enable very smooth movements of the microrobot, suggesting application for any task where repeatable and dexterous movements in liquid microenvironments are key requirements. 漏 2004-2012 IEEE." /> <meta name="DC.contributor" content="Istituto di Biorobotica" xml:lang="*" /> <meta name="DC.contributor" content="529" xml:lang="*" /> <meta name="DC.subject" content="Control architectures" xml:lang="*" /> <meta name="DC.subject" content="lab-on-a-chip" xml:lang="*" /> <meta name="DC.subject" content="magnetic navigation" xml:lang="*" /> <meta name="DC.subject" content="microrobot" xml:lang="*" /> <meta name="DC.date" content="2023/05/16 11:30:43" xml:lang="*" scheme="DCTERMS.W3CDTF" /> <meta name="DC.date" content="1684229443776" xml:lang="*" scheme="DCTERMS.W3CDTF" /> <meta name="DC.contributor" content="Non assegn" xml:lang="*" /> <meta name="DC.contributor" content="AREA MIN. 09 - Ingegneria industriale e dell'informazione" xml:lang="*" /> <meta name="DC.contributor" content="AREA MIN. 09 - Ingegneria industriale e dell'informazione" xml:lang="*" /> <meta name="DC.contributor" content="Non assegn" xml:lang="*" /> <meta name="DC.contributor" content="AREA MIN. 09 - Ingegneria industriale e dell'informazione" xml:lang="*" /> <meta name="DC.contributor" content="Non assegn" xml:lang="*" /> <meta name="DC.description" content="Lucarini G.; Palagi S.; Levi A.; Mazzolai B.; Dario P.; Menciassi A.; Beccai L." xml:lang="en" /> <meta name="DC.description" content="Lucarini, G.; Palagi, S.; Levi, A.; Mazzolai, B.; Dario, P.; Menciassi, A.; Beccai, L." /> <meta name="citation_title" content="Navigation of magnetic microrobots with different user interaction levels" /> <meta name="citation_author" content="Lucarini, G." /> <meta name="citation_author_email" content="g.lucarini@reliefsrl.com" /> <meta name="citation_author" content="Palagi, S." /> <meta name="citation_author_email" content="stefano.palagi@santannapisa.it" /> <meta name="citation_author" content="Levi, A." /> <meta name="citation_author_email" content="alessandro.levi@sssup.it" /> <meta name="citation_author" content="Mazzolai, B." /> <meta name="citation_author_email" content="barbara.mazzolai@sssup.it" /> <meta name="citation_author" content="Dario, P." /> <meta name="citation_author_email" content="paolo.dario@santannapisa.it" /> <meta name="citation_author" content="Menciassi, A." /> <meta name="citation_author_email" content="arianna.menciassi@santannapisa.it" /> <meta name="citation_author" content="Beccai, L." /> <meta name="citation_author_email" content="lucia.beccai@sssup.it" /> <meta name="citation_date" content="2014" /> <meta name="citation_issn" content="1545-5955" /> <meta name="citation_journal_title" content="IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING" /> <meta name="citation_volume" content="11" /> <meta name="citation_issue" content="3" /> <meta name="citation_firstpage" content="818" /> <meta name="citation_lastpage" content="827" /> <meta name="citation_doi" content="10.1109/TASE.2014.2317232" /> <meta name="citation_abstract_html_url" content="https://www.iris.sssup.it/handle/11382/545996" /> <meta name="citation_language" content="eng" /> <meta name="citation_keywords" content="Control architectures; lab-on-a-chip; magnetic navigation; microrobot" /> <script type="text/javascript"> $(document).on('click', '.c-bn', function() { location.reload(); }); </script> </head> <body class="body-default body-anonymous"> <header class="navbar navbar-expand-md navbar-dark sticky-top layout-top bg-primary iu-hide"> <nav class="container-fluid flex-wrap flex-md-nowrap" aria-label="menu top"> <a class="navbar-brand ps-0 pt-0 pb-0 pe-3" href="https://www.iris.sssup.it/" aria-label="link homepage" id="uiLogoLink"> <img src="/sr/logo_iris.png" alt="IRIS" id="uiLogoImg" class="d-block my-1 navbar-brand-img"/> </a> <a class="navbar-brand ps-3 pt-0 pb-0 pe-3 me-3" href="" aria-label="link homepage universit脿" id="customerLogoLink"> <img src="/sr/logo_customer.png" alt="IRIS" id="clientLogoImg" class="d-block my-1 navbar-brand-img"/> </a> <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="mostra/nascondi menu"> <span class="fas fa-bars"></span> </button> <div class="collapse navbar-collapse" id="navbarSupportedContent"> <ul class="navbar-nav flex-row flex-wrap pt-2 py-md-0"> </ul> <ul class="navbar-nav flex-row flex-wrap ms-md-auto"> <li class="nav-item col-6 col-md-auto " id="topNavHome"> <a class="nav-link p-2" href="https://www.iris.sssup.it/">Home</a> </li> <li class="nav-item col-6 col-md-auto dropdown"> <a class="nav-link p-2 dropdown-toggle" href="#" id="navbarDropdownBrowse" role="button" data-bs-toggle="dropdown" aria-haspopup="true" aria-expanded="false"> Sfoglia</a> <div class="dropdown-menu" aria-labelledby="navbarDropdownBrowse"> <a class="dropdown-item" href="https://www.iris.sssup.it/community-list">Macrotipologie<br/>&amp;&nbsp;tipologie</a> <div class="dropdown-divider"></div> <a class="dropdown-item" href="https://www.iris.sssup.it/browse?type=author">Autore</a> <a class="dropdown-item" href="https://www.iris.sssup.it/browse?type=title">Titolo</a> <a class="dropdown-item" href="https://www.iris.sssup.it/browse?type=relationJournal">Riviste</a> <a class="dropdown-item" href="https://www.iris.sssup.it/browse?type=relationSerie">Serie</a> </div> </li> </ul> <form class="navbar-search-top d-flex" action="https://www.iris.sssup.it/simple-search" method="get" role="search"> <div class="input-group p-2"> <input class="form-control bg-primary layout-top-input" type="search" placeholder="Search&nbsp;IRIS" name="query" id="tequery" size="25" aria-label="Search&nbsp;IRIS"> <button class="btn btn-primary layout-top-input-btn" type="submit"><span class="fas fa-search"></span></button> </div> </form> <ul class="navbar-nav flex-row flex-wrap"> <li class="nav-item col-6 col-md-auto dropdown"> <a class="nav-link p-2 dropdown-toggle" href="#" id="navbarDropdownLanguage" role="button" data-bs-toggle="dropdown" aria-haspopup="true" aria-expanded="false"> IT</a> <div class="dropdown-menu dropdown-menu-end" aria-labelledby="navbarDropdownLanguage"> <a class="dropdown-item" href="javascript:reloadLanguageModuleAll('https://www.iris.sssup.it',['bi','rm','gw','ma','','saiku','ap'],'/language/change.json','it');" ><img src="/sr/cineca/images/flag/flag_it.png" alt="Italiano" title=""/>&nbsp;Italiano</a> <a class="dropdown-item" href="javascript:reloadLanguageModuleAll('https://www.iris.sssup.it',['bi','rm','gw','ma','','saiku','ap'],'/language/change.json','en');" ><img src="/sr/cineca/images/flag/flag_en.png" alt="English" title="English"/>&nbsp;English</a> </div> </li> <li class="nav-item col-6 col-md-auto "> <script type="text/javascript"> <!-- Javascript starts here document.write('<a class="nav-link p-2" href="#" onClick="var popupwin = window.open(\'https://wiki.u-gov.it/confluence/x/HJEWAw\',\'dspacepopup\',\'height=600,width=850,resizable,scrollbars\');popupwin.focus();return false;"><span class="fas fa-question-circle" title="Aiuto"></span></a>'); 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Their application in lab-on-a-chip systems, such as micromanipulation and in vitro cell sorting, is expected to steeply increase. However, the actuation, powering and control of microrobots are challenges that still need concrete solutions. Magnetic fields generally enable wireless navigation of microrobots, but proper control architectures and magnetic navigation systems are needed, depending on the specific task and on the level of interaction required to the user. Here we present a magnetic navigation platform intended for lab-on-a-chip applications and we address its usability with different levels of human involvement by using two control architectures: teleoperated and autonomous. We perform an experimental analysis to demonstrate that both architectures, enrolling different levels of interaction by the user, lead to reliable execution of the microrobotic task. First, we validate the open-loop response of the microrobotic system, and second, we evaluate the performance of the system by testing both control architectures with a standard mobility task. The results show that users can teleoperate the microrobot with 100% success rate, in 14.4 卤 1.9s with a normalized spatial mean error of 0.60 卤 0.13. Moreover, results show a fast decaying learning curve for the users involved in the study. Compared to this, when the navigation task is performed by the autonomous control, 100% success rate, a time of 8.0 卤 0.5s and a normalized spatial mean error of 0.50 卤 0.05 are obtained. Finally, we quantitatively demonstrate how both control methodologies enable very smooth movements of the microrobot, suggesting application for any task where repeatable and dexterous movements in liquid microenvironments are key requirements. 漏 2004-2012 IEEE.</p> <div class="row"> <div class="col-lg-12 col-xl-9"> <div class="card"> <div class="card-body"> <div> <h3 class="mb-1 text-secondary">Navigation of magnetic microrobots with different user interaction levels</h3> <h5> <em><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp01181" class="authority author">Lucarini G.</a><sup class="ms-1"><h6 class="badge bg-info"><span class="fas fa-at" title="Corresponding author"></span></h6></sup>;</span><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp01183" class="authority author">Palagi S.</a>;</span><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp01206" class="authority author">Levi A.</a>;</span><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp00293" class="authority author">Mazzolai B.</a>;</span><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp00223" class="authority author">Dario P.</a>;</span><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp00889" class="authority author">Menciassi A.</a>;</span><span class="contributor internalContributor internalContributordd9e0b33-8723-709e-e053-3705fe0a83fd m-1"><a href="/cris/rp/rp00188" class="authority author">Beccai L.</a></span></em> </h5> <h5>2014-01-01</h5> <hr/> <h4 class="mb-1">Abstract</h4> Micro-technologies based on wirelessly powered and manoeuvred submillimeter device, i.e., microrobots, are attracting growing attention. Their application in lab-on-a-chip systems, such as micromanipulation and in vitro cell sorting, is expected to steeply increase. However, the actuation, powering and control of microrobots are challenges that still need concrete solutions. Magnetic fields generally enable wireless navigation of microrobots, but proper control architectures and magnetic navigation systems are needed, depending on the specific task and on the level of interaction required to the user. Here we present a magnetic navigation platform intended for lab-on-a-chip applications and we address its usability with different levels of human involvement by using two control architectures: teleoperated and autonomous. We perform an experimental analysis to demonstrate that both architectures, enrolling different levels of interaction by the user, lead to reliable execution of the microrobotic task. First, we validate the open-loop response of the microrobotic system, and second, we evaluate the performance of the system by testing both control architectures with a standard mobility task. The results show that users can teleoperate the microrobot with 100% success rate, in 14.4 卤 1.9s with a normalized spatial mean error of 0.60 卤 0.13. Moreover, results show a fast decaying learning curve for the users involved in the study. Compared to this, when the navigation task is performed by the autonomous control, 100% success rate, a time of 8.0 卤 0.5s and a normalized spatial mean error of 0.50 卤 0.05 are obtained. Finally, we quantitatively demonstrate how both control methodologies enable very smooth movements of the microrobot, suggesting application for any task where repeatable and dexterous movements in liquid microenvironments are key requirements. 漏 2004-2012 IEEE. </div> <div class="dspace-display-item tabbable page-tabs mt-3"> <h5> <ul class="nav nav-tabs border-bottom fw-bold"> <li class="nav-item"><a class="nav-link active" href="#tab_default" onclick="changeItemView('simple');" data-bs-toggle="tab">Scheda breve</a></li> <li class="nav-item"><a class="nav-link " href="#tab_default" onclick="changeItemView('complete');" data-bs-toggle="tab">Scheda completa</a></li> <li class="nav-item"><a class="nav-link " href="#tab_default" onclick="changeItemView('full');" data-bs-toggle="tab">Scheda completa (DC)</a></li> <li class="nav-item"><a class="nav-link" onclick="location.href='/cris/item/11382/545996/statistics'" data-bs-toggle="tab"><span class="far fa-chart-bar"></span></a></li> </ul> </h5> <div class="tab-content"> <div class="tab-pane active fade show" id="tab_default"> <div class="itemDisplayTable container-fluid g-3"> <div class="line form-group row metadataFieldValue pt-2 pb-2 dc_date_issued" id="dc.date.issued_line" > <div class="line-label col-md-12"><label for="dc.date.issued" class="control-label metadataFieldLabel dc_date_issued"> <span class="line-label-text">Anno del prodotto</span> </label></div> <div class="line-content col-sm-12" id="dc.date.issued_content"> <em>2014</em> </div> </div> <div class="line form-group row metadataFieldValue pt-2 pb-2 dspace_collection" id="dspace_collection_line" > <div class="line-label col-md-12"><label for="dspace_collection" class="control-label metadataFieldLabel dspace_collection"> <span class="line-label-text">Appare nelle tipologie:</span> </label></div> <div class="line-content col-sm-12" id="dspace_collection_content"> <a href="/handle/11382/496776">1.1 Articolo su Rivista/Article</a> </div> </div> </div> </div> </div> </div></div> </div> <script type="text/x-tmpl" id="tmpLicenseDetail"> <div class="d-flex align-items-center"> {% if (o.licenseImage != null) { %} <div class="flex-shrink-0"> <img src="{%= o.licenseImage %}" /> </div> {% } %} <div class="flex-grow-1 ms-3"> {%# o.licenseName %} </div> </div> </script> <div id="bitstreams" class="card bg-white mt-2"> <div class="card-header">File in questo prodotto:</div> <div class="card-body">Non ci sono file associati a questo prodotto.</div> </div> <div class="col-lg-12 mt-2"> </div> <div class="col-lg-12 mt-2"> <p class="submitFormHelp alert alert-info">I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.</p> </div> </div> <div class="col-lg-12 col-xl-3" id="itemInformationsDiv"> <div id="_line" > <div class="accordion" id="accordion_"> <div class="accordion-item"> <h5 class="accordion-header" id="heading_"> <button class="accordion-button bg-info bg-opacity-25 collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse_" aria-expanded="false" aria-controls="collapse_"><i class="fas fa-info-circle"></i>&nbsp;Informazioni</button> </h5> <div id="collapse_" class="accordion-collapse collapse show" aria-labelledby="heading_" data-bs-parent="#accordion_"> <div class="accordion-body"> Utilizza questo identificativo per citare o creare un link a questo documento: <code>https://hdl.handle.net/11382/545996</code> </div> </div> </div> </div> </div> <script type="text/javascript"> runningExternal=false; 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