Mass Spectrometry

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</script> </head> <body class="front not-logged-in page-home one-sidebar sidebar-second og-context og-context-22 navbar-on header-left-right"> <div id="page"> <div id="page-wrapper"> <div id="header"> <div class="wrap clearfix"> <div class="hg-container"> <div id="header-left" class="column"> <div id="block-boxes-og-22-63483261" class="box-os_boxes_modal_image block region-odd odd region-count-1 count-3"> <div class="content"> <div id='boxes-box-og-22-63483261' class='boxes-box'><div class="boxes-box-content"><a href="http://gladstoneinstitutes.org"><img src="/sites/default/files/imagecache/os_modal_image_500/mass_spectrometry/files/logo.png" alt="" title="" class="imagecache imagecache-os_modal_image_500 imagecache-default imagecache-os_modal_image_500_default" width="458" height="58" /></a></div></div> </div> </div>  </div> <div id="header-right" class="column"> <div id="block-boxes-site_info" class="box-os_boxes_modal_siteinfo block region-odd even region-count-1 count-4"> <div class="content"> <div id='boxes-box-site_info' class='boxes-box'><div class="boxes-box-content"><h1><a href="http://labs.gladstone.org/mass_spectrometry/">Mass Spectrometry</a></h1><h2>Gladstone Core Services</h2></div></div> </div> </div>  </div> </div> </div> </div> <div id="navbar"> <div class="wrap clearfix"> <div id="block-vsite_menus-features" class="block region-odd odd region-count-1 count-5"> <div class="content"> <ul class="menu"><li class="leaf first"><a href="index.html" class="active">Home</a></li>  <li class="leaf"><a href="links.html" title="List of links">Resources</a></li> <li class="collapsed last"><a href="publications.html">Publications</a></li> </ul> </div> </div>  </div> </div> <div id="content-area"> <div class="wrap clearfix"> <div class="hg-container"> <div id="content-main" class="column content-left content-right"> <div id="content-top"> <div id="block-boxes-og-22-feda0fe8" class="box-os_boxes_simple block region-odd even region-count-1 count-6"> <div class="content"> <div id='boxes-box-og-22-feda0fe8' class='boxes-box'><div class="boxes-box-content"><p><em><strong>The QB3@UCSF-Gladstone Mass Spectrometry Laboratory </strong>provides investigators with state-of-the-art technology to characterize protein dynamics in biological systems.<br /></em></p> </div></div> </div> </div>  </div> <div id="content"> <h2 class="title">Home</h2> </div>  <div id="content-left"> <div id="block-boxes-og-22-26857084" class="box-os_boxes_modal_image block region-odd odd region-count-1 count-7"> <div class="content"> <div id='boxes-box-og-22-26857084' class='boxes-box'><div class="boxes-box-content"><img src="/sites/default/files/imagecache/os_modal_image_300/mass_spectrometry/files/mass-spec-screen-11-2-sml.jpg" alt="" title="" class="imagecache imagecache-os_modal_image_300 imagecache-default imagecache-os_modal_image_300_default" width="300" height="299" /><p><em>Photo courtesy of Chris Goodfellow</em></p> </div></div> </div> </div>  </div> <div id="content-right"> <div id="block-boxes-og-22-8f520d0" class="box-os_boxes_simple block region-odd even region-count-1 count-8"> <div class="content"> <div id='boxes-box-og-22-8f520d0' class='boxes-box'><div class="boxes-box-content"><p>The Mass Spectrometry Core was established in late 2011 and currently is comprised of two mass spectrometry systems. We provide a number of proteomics approaches for users' applications, including characterization of protein-protein interactions, composition analysis of complex protein mixtures, quantitative analysis of protein abundance, and characterization of post-translational modifications such as phosphorylation, ubiquitylation, and acetylation. Please consults our <a href="http://labs.gladstone.ucsf.edu/mass_spectrometry/links">Resources</a> page for details on instrumentation and the proteomics approaches that we employ.</p> <p>The Mass Spectrometry Core currently operates on a collaborative basis and provides services at cost. The faculty adviser for the Mass Spectrometry Core is Nevan Krogan.</p> <p><strong>We are open to all UCSF and Gladstone investigators! </strong>Please visit our <a title="Resources" style="font-size: 13px; background-color: #ffffff;" href="http://labs.gladstone.ucsf.edu/mass_spectrometry/links" target="_blank">Resources</a> page for more information. </p> </div></div> </div> </div>  </div> </div> <div id="sidebar-second" class="sidebar column"> <div id="block-boxes-scholar_publications_recent" class="box-os_boxes_pub_typ_list block region-even even region-count-2 count-2"> <h3 class="title">Recent Publications</h3> <div class="content"> <div id='boxes-box-scholar_publications_recent' class='boxes-box'><div class="boxes-box-content"><div class="view view-publication-types view-id-publication_types view-display-id-block_3 view-dom-id-boxes-scholar_publications_recent"> <ul> <li class="views-row views-row-1 views-row-odd views-row-first"> <div class="views-field-title"> <span class="field-content"><a target="_blank" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=NF-kappaB-Activating+Complex+Engaged+in+Response+to+EGFR+Oncogene+Inhibition+Drives+Tumor+Cell+Survival+and+Residual+Disease+in+Lung+Cancer">NF-kappaB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer</a></span> </div> </li> <li class="views-row views-row-2 views-row-even"> <div class="views-field-title"> <span class="field-content"><a target="_blank" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Pharmacological+dimerization+and+activation+of+the+exchange+factor+eIF2B+antagonizes+the+integrated+stress+response">Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response</a></span> </div> </li> <li class="views-row views-row-3 views-row-odd"> <div class="views-field-title"> <span class="field-content"><a target="_blank" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Global+mapping+of+herpesvirus-host+protein+complexes+reveals+a+transcription+strategy+for+late+genes">Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes</a></span> </div> </li> <li class="views-row views-row-4 views-row-even"> <div class="views-field-title"> <span class="field-content"><a target="_blank" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=A+combined+proteomics%2Fgenomics+approach+links+hepatitis+C+virus+infection+with+nonsense-mediated+mRNA+decay">A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay</a></span> </div> </li> <li class="views-row views-row-5 views-row-odd"> <div class="views-field-title"> <span class="field-content"><a target="_blank" href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Linking+Tumor+Mutations+to+Drug+Responses+via+a+Quantitative+Chemical-Genetic+Interaction+Map">Linking Tumor Mutations to Drug Responses via a Quantitative Chemical-Genetic Interaction Map</a></span> </div> </li> <li class="views-row views-row-6 views-row-even views-row-last"> <div class="views-field-title"> <span class="field-content"><a href="https://www.ncbi.nlm.nih.gov/pubmed/25275790">Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions</a></span> </div> </li> </ul> </div> <div class="more-link"> <a href="publications.html"> more </a> </div> </div></div> </div> </div>  </div>  </div>  </div> </div>  <div id="footer"> <div class="wrap clearfix"> <p class="copy"> <span id="powered-link"><a href="http://openscholar.harvard.edu" class="poweredby">Powered by OpenScholar</a></p><img src="https://labs.gladstone.org/sites/default/files/spacer.gif?version=2.0-BETA14_Drupal_6.26&openscholar_version=2.0-BETA14&vsite=mass_spectrometry&host=http%3A%2F%2Flabs.gladstone.org&age=1337717412" /> </div> </div>  </div> </div>  <div id="extradiv"></div> </body> </html>

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Mass Spectrometry