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Non-thermal Plasma Promotes Boar Sperm Quality Through Increasing AMPK Methylation
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/></div></noscript> <!-- /Yandex.Metrika counter --> <!-- Matomo --> <!-- End Matomo Code --> <title>Non-thermal Plasma Promotes Boar Sperm Quality Through Increasing AMPK Methylation</title> <meta name="description" content="Non-thermal Plasma Promotes Boar Sperm Quality Through Increasing AMPK Methylation"> <meta name="keywords" content="non-thermal DBD plasma, sperm quality, AMPK methylation, energy metabolism, antioxidant capacity"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div 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class="card"> <div class="card-body"><strong>Paper Count:</strong> 87351</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Non-thermal Plasma Promotes Boar Sperm Quality Through Increasing AMPK Methylation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jiaojiao%20Zhang">Jiaojiao Zhang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Boar sperm quality, as an important indicator of reproductive efficiency, directly affects the efficiency of livestock production. Here, this study was conducted to improve the boar sperm quality by using a non-thermal dielectric barrier discharge (DBD) plasma. Our results showed that DBD plasma exposure at 2.1 W for 15 s could improve boar sperm quality by increasing the exon methylation level of adenosine monophosphate-activated protein kinase (AMPK) and thus improving the glycolytic flux, mitochondrial function, and antioxidant capacity without damaging the integrity of sperm DNA and acrosome. In addition, DBD plasma could rescue DNA methyltransferase inhibitor decitabine-caused low sperm quality by reducing oxidative stress and mitochondrial damage. Therefore, the application of non-thermal plasma provides a new strategy for reducing sperm oxidative damage and improving sperm quality, which shows great potential in assisted reproduction to solve the problem of male infertility. <iframe src="https://publications.waset.org/abstracts/193854.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=non-thermal%20DBD%20plasma" title="non-thermal DBD plasma">non-thermal DBD plasma</a>, <a href="https://publications.waset.org/abstracts/search?q=sperm%20quality" title=" sperm quality"> sperm quality</a>, <a href="https://publications.waset.org/abstracts/search?q=AMPK%20methylation" title=" AMPK methylation"> AMPK methylation</a>, <a href="https://publications.waset.org/abstracts/search?q=energy%20metabolism" title=" energy metabolism"> energy metabolism</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20capacity" title=" antioxidant capacity"> antioxidant capacity</a> </p> <a href="https://publications.waset.org/abstracts/193854/non-thermal-plasma-promotes-boar-sperm-quality-through-increasing-ampk-methylation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193854.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">9</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" 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