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Search results for: Aleksandar Simic
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class="container mt-4"> <div class="row"> <div class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Aleksandar Simic"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 38</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Aleksandar Simic</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">38</span> Importance of CT and Timed Barium Esophagogram in the Contemporary Treatment of Patients with Achalasia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Jovanovic">Sanja Jovanovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Simic"> Aleksandar Simic</a>, <a href="https://publications.waset.org/abstracts/search?q=Ognjan%20Skrobic"> Ognjan Skrobic</a>, <a href="https://publications.waset.org/abstracts/search?q=Dragan%20Masulovic"> Dragan Masulovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandra%20Djuric-Stefanovic"> Aleksandra Djuric-Stefanovic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Achalasia is an idiopathic primary esophageal motility disorder characterized by esophageal peristalsis and impaired swallow-induced relaxation of the lower esophageal sphincter (LES). It is a rare disease that affects both genders with an incidence of 1/100.000 and a prevalence rate of 10/100,000 per year. Objective: Laparoscopic Heller myotomy (LHM) represents a therapy of choice for patients with achalasia, providing excellent outcomes. The aim of this study was to evaluate the significance of computed tomography (CT) in analyzing achalasia subtypes and timed barium esophagogram (TBE) in evaluation of LHM success, as a part of standardized diagnostic protocol. Method: Fifty-one patients with achalasia, confirmed by manometric studies, in addition to standardized diagnostic methods, underwent CT and TBE. CT was done with multiplanar reconstruction, measuring the wall thickness above the esophago-gastric junction in the axial plane. TBE was performed preoperatively and two days postoperatively swallowing low-density barium sulfate, and plane upright frontal films were performed 1, 2 and 5 minutes after the ingestion. In all patients, LHM was done, and pre and postoperative height and weight of the barium column were compared. Results: According to CT findings we divided patients into 3 subtypes of achalasia according to wall thickness: < 4mm as subtype one, between 4 - 9mm as II, and > 10 mm as subtype 3. Correlation of manometric results, as a reference values, and CT findings indicated CT sensitivity of 90% and specificity of 70 % in establishing subtypes of achalasia. The preoperative values of TBE at 1, 2 and 5 minutes were: median barium column height 17.4 ± 7.4, 15.9 ± 6.2 and 13.9 ± 6.2 cm; median column width 5 ± 1.5, 4.7 ± 1.6 and 4.5 ± 1.8 cm respectively. LHM significantly reduced these values (height 7 ± 4.6, 5.8 ± 4.2, 3.7 ± 3.4 cm; width 2.9 ± 1.3, 2.6 ± 1.3 and 2.4 ± 1.4 cm), indicating the quantitative estimates of emptying as excellent (p value < 0.01). Conclusion: CT has high sensitivity and specificity in evaluation of achalasia subtypes, and can be introduced as an additional method for standardized evaluation of these patients. The quantitative assessment of TBE based on measurements of the barium column is an accurate and beneficial method, which adequately estimates esophageal emptying success of LHM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=achalasia" title="achalasia">achalasia</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=esophagography" title=" esophagography"> esophagography</a>, <a href="https://publications.waset.org/abstracts/search?q=myotomy" title=" myotomy"> myotomy</a> </p> <a href="https://publications.waset.org/abstracts/83526/importance-of-ct-and-timed-barium-esophagogram-in-the-contemporary-treatment-of-patients-with-achalasia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83526.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">235</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">37</span> Towards a Framework for Evaluating Scientific Efficiency of World-Class Universities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Veljko%20Jeremic">Veljko Jeremic</a>, <a href="https://publications.waset.org/abstracts/search?q=Milica%20Kostic%20Stankovic"> Milica Kostic Stankovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Markovic"> Aleksandar Markovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Milan%20Martic"> Milan Martic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Evaluating the efficiency of decision making units has been frequently elaborated on in numerous publications. In this paper, the theoretical framework for a novel method of Distance Based Analysis (DBA) is presented. In addition, the method is performed on a sample of the ARWU’s top 54 Universities of the United States, the findings of which clearly demonstrate that the best ranked Universities are far from also being the most efficient. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=evaluating%20efficiency" title="evaluating efficiency">evaluating efficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=distance%20based%20analysis" title=" distance based analysis"> distance based analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=ranking%20of%20universities" title=" ranking of universities"> ranking of universities</a>, <a href="https://publications.waset.org/abstracts/search?q=ARWU" title=" ARWU"> ARWU</a> </p> <a href="https://publications.waset.org/abstracts/2623/towards-a-framework-for-evaluating-scientific-efficiency-of-world-class-universities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2623.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">296</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">36</span> Economic Neoliberalism: Property Right and Redistribution Policy </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Savanovi%C4%87">Aleksandar Savanović</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper we will analyze the relationship between the neo-liberal concept of property rights and redistribution policy. This issue is back in the focus of interest due to the crisis 2008. The crisis has reaffirmed the influence of the state on the free-market processes. The interference of the state with property relations re-opened a classical question: is it legitimate to redistribute resources of a man in favor of another man with taxes? The dominant view is that the neoliberal philosophy of natural rights is incompatible with redistributive measures. In principle, this view can be accepted. However, when we look into the details of the theory of natural rights proposed by some coryphaei of neoliberal philosophy, such as Hayek, Nozick, Buchanan and Rothbard, we can see that it is not such an unequivocal view. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=economic%20neoliberalism" title="economic neoliberalism">economic neoliberalism</a>, <a href="https://publications.waset.org/abstracts/search?q=natural%20law" title=" natural law"> natural law</a>, <a href="https://publications.waset.org/abstracts/search?q=property" title=" property"> property</a>, <a href="https://publications.waset.org/abstracts/search?q=redistribution" title=" redistribution"> redistribution</a> </p> <a href="https://publications.waset.org/abstracts/22995/economic-neoliberalism-property-right-and-redistribution-policy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22995.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">376</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">35</span> Nano Effects of Nitrogen Ion Implantation on TiN Hard Coatings Deposited by Physical Vapour Deposition and Ion Beam Assisted Deposition</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Branko%20Skoric">Branko Skoric</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Miletic"> Aleksandar Miletic</a>, <a href="https://publications.waset.org/abstracts/search?q=Pal%20Terek"> Pal Terek</a>, <a href="https://publications.waset.org/abstracts/search?q=Lazar%20Kovacevic"> Lazar Kovacevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Milan%20Kukuruzovic"> Milan Kukuruzovic </a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, we present the results of a study of TiN thin films which are deposited by a Physical Vapour Deposition (PVD) and Ion Beam Assisted Deposition (IBAD). In the present investigation the subsequent ion implantation was provided with N<sup>5+</sup> ions. The ion implantation was applied to enhance the mechanical properties of surface. The thin film deposition process exerts a number of effects such as crystallographic orientation, morphology, topography, densification of the films. A variety of analytic techniques were used for characterization, such as scratch test, calo test, Scanning electron microscopy (SEM), Atomic Force Microscope (AFM), X-ray diffraction (XRD) and Energy Dispersive X-ray analysis (EDAX). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=coating" title="coating">coating</a>, <a href="https://publications.waset.org/abstracts/search?q=super%20hard" title=" super hard"> super hard</a>, <a href="https://publications.waset.org/abstracts/search?q=ion%20implantation" title=" ion implantation"> ion implantation</a>, <a href="https://publications.waset.org/abstracts/search?q=nanohardness" title=" nanohardness"> nanohardness</a> </p> <a href="https://publications.waset.org/abstracts/42278/nano-effects-of-nitrogen-ion-implantation-on-tin-hard-coatings-deposited-by-physical-vapour-deposition-and-ion-beam-assisted-deposition" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42278.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">346</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">34</span> Reconnecting The Peripheral Wagons to the Euro Area Core Locomotive</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Igor%20Velickovski">Igor Velickovski</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Stojkov"> Aleksandar Stojkov</a>, <a href="https://publications.waset.org/abstracts/search?q=Ivana%20Rajkovic"> Ivana Rajkovic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper investigates drivers of shock synchronization using quarterly data for 27 European countries over the period 1999-2013 and taking into account the difference between core (‘the euro area core locomotive’) and peripheral euro area and transition countries (‘the peripheral wagons’). Results from panel error-correction models suggest that core of the euro area has not been strong magnetizer of the shock convergence of periphery and transition countries since the euro inception as a result of the offsetting effects of the various factors that affected the shock convergence process. These findings challenge the endogeneity hypothesis in the optimum currency area framework and rather support the specialisation paradigm which is concerning evidence for the future stability of the euro area. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dynamic%20panel%20models" title="dynamic panel models">dynamic panel models</a>, <a href="https://publications.waset.org/abstracts/search?q=shock%20synchronisation" title=" shock synchronisation"> shock synchronisation</a>, <a href="https://publications.waset.org/abstracts/search?q=trade" title=" trade"> trade</a>, <a href="https://publications.waset.org/abstracts/search?q=optimum%20currency%20area" title=" optimum currency area"> optimum currency area</a> </p> <a href="https://publications.waset.org/abstracts/35361/reconnecting-the-peripheral-wagons-to-the-euro-area-core-locomotive" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35361.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">358</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">33</span> Traffic Signal Control Using Citizens’ Knowledge through the Wisdom of the Crowd</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Jovanovic">Aleksandar Jovanovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Kukic"> Katarina Kukic</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Uzelac"> Ana Uzelac</a>, <a href="https://publications.waset.org/abstracts/search?q=Dusan%20Teodorovic"> Dusan Teodorovic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Wisdom of the Crowd (WoC) is a decentralized method that uses the collective intelligence of humans. Individual guesses may be far from the target, but when considered as a group, they converge on optimal solutions for a given problem. We will utilize WoC to address the challenge of controlling traffic lights within intersections from the streets of Kragujevac, Serbia. The problem at hand falls within the category of NP-hard problems. We will employ an algorithm that leverages the swarm intelligence of bees: Bee Colony Optimization (BCO). Data regarding traffic signal timing at a single intersection will be gathered from citizens through a survey. Results obtained in that manner will be compared to the BCO results for different traffic scenarios. We will use Vissim traffic simulation software as a tool to compare the performance of bees’ and humans’ collective intelligence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=wisdom%20of%20the%20crowd" title="wisdom of the crowd">wisdom of the crowd</a>, <a href="https://publications.waset.org/abstracts/search?q=traffic%20signal%20control" title=" traffic signal control"> traffic signal control</a>, <a href="https://publications.waset.org/abstracts/search?q=combinatorial%20optimization" title=" combinatorial optimization"> combinatorial optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=bee%20colony%20optimization" title=" bee colony optimization"> bee colony optimization</a> </p> <a href="https://publications.waset.org/abstracts/174794/traffic-signal-control-using-citizens-knowledge-through-the-wisdom-of-the-crowd" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174794.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">108</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">32</span> Influence of Vacuum Pressure on the Thermal Bonding Energy of Water in Wood</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Dedic">Aleksandar Dedic</a>, <a href="https://publications.waset.org/abstracts/search?q=Dusko%20Salemovic"> Dusko Salemovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Milorad%20Danilovic"> Milorad Danilovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Radomir%20Kuzmanovic"> Radomir Kuzmanovic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper takes into consideration the influence of bonding energy of water on energy demand of vacuum wood drying using the specific method of obtaining sorption isotherms. The experiment was carried out on oak wood at vacuum pressures of: 0.7 bar, 0.5bar and 0.3bar. The experimental work was done to determine a mathematical equation between the moisture content and energy of water-bonding. This equation helps in finding the average amount of energy of water-bonding necessary in calculation of energy consumption by use of the equation of heat balance in real drying chambers. It is concluded that the energy of water-bonding is large enough to be included into consideration. This energy increases at lower values of moisture content, when drying process approaches to the end, and its average values are lower on lower pressure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bonding%20energy" title="bonding energy">bonding energy</a>, <a href="https://publications.waset.org/abstracts/search?q=drying" title=" drying"> drying</a>, <a href="https://publications.waset.org/abstracts/search?q=isosters" title=" isosters"> isosters</a>, <a href="https://publications.waset.org/abstracts/search?q=oak" title=" oak"> oak</a>, <a href="https://publications.waset.org/abstracts/search?q=vacuum" title=" vacuum"> vacuum</a> </p> <a href="https://publications.waset.org/abstracts/69758/influence-of-vacuum-pressure-on-the-thermal-bonding-energy-of-water-in-wood" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69758.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">31</span> Thermal Analysis of Vertical Kiln Dryer for Drying Sunflower Seeds in the Oil Mill “Banat” Ad, Nova Crnja</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Dedi%C4%87">Aleksandar Dedić</a>, <a href="https://publications.waset.org/abstracts/search?q=Du%C5%A1ko%20Salemovi%C4%87"> Duško Salemović</a>, <a href="https://publications.waset.org/abstracts/search?q=Matilda%20Lazi%C4%87"> Matilda Lazić</a>, <a href="https://publications.waset.org/abstracts/search?q=Dragan%20Halas"> Dragan Halas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the paper was the thermal balance control of vertical kiln dryer indirect type (VSU-36) for drying sunflower seed, produced by "Cer" - Cacak, capacity 39 [t/h]. The balance control was executed because the dryer was damaged by NATO bombing in 1999, and it was planned for its reconstruction. The structural and geometric characteristics of the dryer were known, and it was necessary to determine the parameters of wet air as a drying agent and the sunflower seeds. The thermal balance control was the basis for the replacement of damaged parts of the dryer during its reconstruction. After that, it was necessary to perform the subsequent calculation of strength. The accuracy of strength had a large influence on the cost-effectiveness and safety of a single drying chamber. Also, the work provides guidelines for the regimes of drying grain crops with an explanation of the specificity of drying sunflowers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sunflower%20seeds" title="sunflower seeds">sunflower seeds</a>, <a href="https://publications.waset.org/abstracts/search?q=regimes%20of%20drying" title=" regimes of drying"> regimes of drying</a>, <a href="https://publications.waset.org/abstracts/search?q=vertical%20kiln%20dryer" title=" vertical kiln dryer"> vertical kiln dryer</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20analysis" title=" thermal analysis"> thermal analysis</a> </p> <a href="https://publications.waset.org/abstracts/176793/thermal-analysis-of-vertical-kiln-dryer-for-drying-sunflower-seeds-in-the-oil-mill-banat-ad-nova-crnja" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/176793.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">70</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">30</span> Monitoring of Pesticide Content in Biscuits Available on the Vojvodina Market, Serbia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ivana%20Loncarevic">Ivana Loncarevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Biljana%20Pajin"> Biljana Pajin</a>, <a href="https://publications.waset.org/abstracts/search?q=Ivana%20Vasiljevic"> Ivana Vasiljevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Milana%20Lazovic"> Milana Lazovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Danica%20Mrkajic"> Danica Mrkajic</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Fises"> Aleksandar Fises</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Kovacevic"> Strahinja Kovacevic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biscuits belong to a group of flour-confectionery products that are considerably consumed worldwide. The basic raw material for their production is wheat flour or integral flour as a nutritionally highly valuable component. However, this raw material is also a potential source of contamination since it may contain the residues of biochemical compounds originating from plant and soil protection agents. Therefore, it is necessary to examine the health safety of both raw materials and final products. The aim of this research was to examine the content of undesirable residues of pesticides (mostly organochlorine pesticides, organophosphorus pesticides, carbamate pesticides, triazine pesticides, and pyrethroid pesticides) in 30 different biscuit samples of domestic origin present on the Vojvodina market using Gas Chromatograph Thermo ISQ/Trace 1300. The results showed that all tested samples had the limit of detection of pesticide content below 0.01 mg/kg, indicating that this type of confectionary products is not contaminated with pesticides. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biscuits" title="biscuits">biscuits</a>, <a href="https://publications.waset.org/abstracts/search?q=pesticides" title=" pesticides"> pesticides</a>, <a href="https://publications.waset.org/abstracts/search?q=contamination" title=" contamination"> contamination</a>, <a href="https://publications.waset.org/abstracts/search?q=quality" title=" quality"> quality</a> </p> <a href="https://publications.waset.org/abstracts/100321/monitoring-of-pesticide-content-in-biscuits-available-on-the-vojvodina-market-serbia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/100321.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">29</span> Moral Reasoning among Croatian Adolescents with Different Levels of Education</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nata%C5%A1a%20%C5%A0imi%C4%87">Nataša Šimić</a>, <a href="https://publications.waset.org/abstracts/search?q=Ljiljana%20Gregov"> Ljiljana Gregov</a>, <a href="https://publications.waset.org/abstracts/search?q=Matilda%20Nikoli%C4%87"> Matilda Nikolić</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Toki%C4%87"> Andrea Tokić</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Prorokovi%C4%87"> Ana Proroković</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Moral development takes place in six phases which can be divided in a pre-conventional, conventional and post-conventional level. Moral reasoning, as a key concept of moral development theories, involves a process of discernment/inference in doubtful situations. In research to date, education has proved to be a significant predictor of moral reasoning. The aim of this study was to investigate differences in moral reasoning and Kohlberg's phases of moral development between Croatian adolescents with different levels of education. In Study 1 comparisons between the group of secondary school students aged 17-18 (N=192) and the group of university students aged 21-25 (N=383) were made. Study 2 included comparison between university students group (N=69) and non-students group (N=43) aged from 21 to 24 (these two groups did not differ in age). In both studies, the Croatian Test of Moral Reasoning by Proroković was applied. As a measure of moral reasoning, the Index of Moral Reasoning (IMR) was calculated. This measure has some advantages compared to other measures of moral reasoning, and includes individual assessments of deviations from the ‘optimal profile’. Results of the Study 1 did not show differences in the IMR between secondary school students and university students. Both groups gave higher assessments to the arguments that correspond to higher phases of moral development. However, group differences were found for pre-conventional and conventional phases. As expected, secondary school students gave significantly higher assessments to the arguments that correspond to lower phases of moral development. Results of the Study 2 showed that university students, in relation to non-students, have higher IMR. Respecting to phases of moral development, both groups of participants gave higher assessments to the arguments that correspond to the post-conventional phase. Consistent with expectations and previous findings, results of both studies did not confirm gender differences in moral reasoning. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=index%20of%20moral%20reasoning" title=" index of moral reasoning"> index of moral reasoning</a>, <a href="https://publications.waset.org/abstracts/search?q=Kohlberg%27s%20theory%20of%20moral%20development" title=" Kohlberg's theory of moral development"> Kohlberg's theory of moral development</a>, <a href="https://publications.waset.org/abstracts/search?q=moral%20reasoning" title=" moral reasoning"> moral reasoning</a> </p> <a href="https://publications.waset.org/abstracts/60656/moral-reasoning-among-croatian-adolescents-with-different-levels-of-education" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60656.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">250</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28</span> International College Students Understand Entrepreneurial Readiness and Business-Related Skills: A Qualitative Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Chonevski">Aleksandar Chonevski</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The free-market economy provides many opportunities for entrepreneurship or starting one’s own business, attracting many students to study business at for-profit colleges in the United States. This is also true for international students, many of whom are filled with the hope of making a better life for themselves and their families through entrepreneurial endeavors. This qualitative research showed that not all graduates business students start their own business. In investigating this phenomenon, the effectiveness of entrepreneurship curricula at international colleges needs to be examined in order to adjust, improve and reform entrepreneurship curricula. This qualitative study will explore how business skills learned in college for-profit play a role in the entrepreneurial readiness of undergraduate business students in the south Florida. Business curricula helps international students achieve goals and transform their actions to understand challenges in a corporate society. Students will be interviewed to gain information about the students’ experience with entrepreneurship curricula in a for-profit college in south Florida. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=business%20skills" title="business skills">business skills</a>, <a href="https://publications.waset.org/abstracts/search?q=college%20curriculum" title=" college curriculum"> college curriculum</a>, <a href="https://publications.waset.org/abstracts/search?q=entrepreneurial%20readiness" title=" entrepreneurial readiness"> entrepreneurial readiness</a>, <a href="https://publications.waset.org/abstracts/search?q=international%20students" title=" international students"> international students</a> </p> <a href="https://publications.waset.org/abstracts/164543/international-college-students-understand-entrepreneurial-readiness-and-business-related-skills-a-qualitative-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/164543.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">76</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">27</span> Optimization of the Measure of Compromise as a Version of Sorites Paradox</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Hatzivelkos">Aleksandar Hatzivelkos</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The term ”compromise” is mostly used casually within the social choice theory. It is usually used as a mere result of the social choice function, and this omits its deeper meaning and ramifications. This paper is based on a mathematical model for the description of a compromise as a version of the Sorites paradox. It introduces a formal definition of d-measure of divergence from a compromise and models a notion of compromise that is often used only colloquially. Such a model for vagueness phenomenon, which lies at the core of the notion of compromise enables the introduction of new mathematical structures. In order to maximize compromise, different methods can be used. In this paper, we explore properties of a social welfare function TdM (from Total d-Measure), which is defined as a function which minimizes the total sum of d-measures of divergence over all possible linear orderings. We prove that TdM satisfy strict Pareto principle and behaves well asymptotically. Furthermore, we show that for certain domain restrictions, TdM satisfy positive responsiveness and IIIA (intense independence of irrelevant alternatives) thus being equivalent to Borda count on such domain restriction. This result gives new opportunities in social choice, especially when there is an emphasis on compromise in the decision-making process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=borda%20count" title="borda count">borda count</a>, <a href="https://publications.waset.org/abstracts/search?q=compromise" title=" compromise"> compromise</a>, <a href="https://publications.waset.org/abstracts/search?q=measure%20of%20divergence" title=" measure of divergence"> measure of divergence</a>, <a href="https://publications.waset.org/abstracts/search?q=minimization" title=" minimization"> minimization</a> </p> <a href="https://publications.waset.org/abstracts/110513/optimization-of-the-measure-of-compromise-as-a-version-of-sorites-paradox" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/110513.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">133</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">26</span> Software Engineering Inspired Cost Estimation for Process Modelling</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Felix%20Baumann">Felix Baumann</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Milutinovic"> Aleksandar Milutinovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Dieter%20Roller"> Dieter Roller</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Up to this point business process management projects in general and business process modelling projects in particular could not rely on a practical and scientifically validated method to estimate cost and effort. Especially the model development phase is not covered by a cost estimation method or model. Further phases of business process modelling starting with implementation are covered by initial solutions which are discussed in the literature. This article proposes a method of filling this gap by deriving a cost estimation method from available methods in similar domains namely software development or software engineering. Software development is regarded as closely similar to process modelling as we show. After the proposition of this method different ideas for further analysis and validation of the method are proposed. We derive this method from COCOMO II and Function Point which are established methods of effort estimation in the domain of software development. For this we lay out similarities of the software development rocess and the process of process modelling which is a phase of the Business Process Management life-cycle. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=COCOMO%20II" title="COCOMO II">COCOMO II</a>, <a href="https://publications.waset.org/abstracts/search?q=busines%20process%20modeling" title=" busines process modeling"> busines process modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=cost%20estimation%20method" title=" cost estimation method"> cost estimation method</a>, <a href="https://publications.waset.org/abstracts/search?q=BPM%20COCOMO" title=" BPM COCOMO"> BPM COCOMO</a> </p> <a href="https://publications.waset.org/abstracts/41029/software-engineering-inspired-cost-estimation-for-process-modelling" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41029.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">441</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">25</span> A Procedure for Post-Earthquake Damage Estimation Based on Detection of High-Frequency Transients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Zhelyazkov">Aleksandar Zhelyazkov</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniele%20Zonta"> Daniele Zonta</a>, <a href="https://publications.waset.org/abstracts/search?q=Helmut%20Wenzel"> Helmut Wenzel</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Furtner"> Peter Furtner</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the current research structural health monitoring is considered for addressing the critical issue of post-earthquake damage detection. A non-standard approach for damage detection via acoustic emission is presented - acoustic emissions are monitored in the low frequency range (up to 120 Hz). Such emissions are termed high-frequency transients. Further a damage indicator defined as the Time-Ratio Damage Indicator is introduced. The indicator relies on time-instance measurements of damage initiation and deformation peaks. Based on the time-instance measurements a procedure for estimation of the maximum drift ratio is proposed. Monitoring data is used from a shaking-table test of a full-scale reinforced concrete bridge pier. Damage of the experimental column is successfully detected and the proposed damage indicator is calculated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acoustic%20emission" title="acoustic emission">acoustic emission</a>, <a href="https://publications.waset.org/abstracts/search?q=damage%20detection" title=" damage detection"> damage detection</a>, <a href="https://publications.waset.org/abstracts/search?q=shaking%20table%20test" title=" shaking table test"> shaking table test</a>, <a href="https://publications.waset.org/abstracts/search?q=structural%20health%20monitoring" title=" structural health monitoring"> structural health monitoring</a> </p> <a href="https://publications.waset.org/abstracts/99423/a-procedure-for-post-earthquake-damage-estimation-based-on-detection-of-high-frequency-transients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99423.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">231</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">24</span> A Review of Benefit-Risk Assessment over the Product Lifecycle</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Miljkovic">M. Miljkovic</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Urakpo"> A. Urakpo</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Simic-Koumoutsaris"> M. Simic-Koumoutsaris</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Benefit-risk assessment (BRA) is a valuable tool that takes place in multiple stages during a medicine's lifecycle, and this assessment can be conducted in a variety of ways. The aim was to summarize current BRA methods used during approval decisions and in post-approval settings and to see possible future directions. Relevant reviews, recommendations, and guidelines published in medical literature and through regulatory agencies over the past five years have been examined. BRA implies the review of two dimensions: the dimension of benefits (determined mainly by the therapeutic efficacy) and the dimension of risks (comprises the safety profile of a drug). Regulators, industry, and academia have developed various approaches, ranging from descriptive textual (qualitative) to decision-analytic (quantitative) models, to facilitate the BRA of medicines during the product lifecycle (from Phase I trials, to authorization procedure, post-marketing surveillance and health technology assessment for inclusion in public formularies). These approaches can be classified into the following categories: stepwise structured approaches (frameworks); measures for benefits and risks that are usually endpoint specific (metrics), simulation techniques and meta-analysis (estimation techniques), and utility survey techniques to elicit stakeholders’ preferences (utilities). All these approaches share the following two common goals: to assist this analysis and to improve the communication of decisions, but each is subject to its own specific strengths and limitations. Before using any method, its utility, complexity, the extent to which it is established, and the ease of results interpretation should be considered. Despite widespread and long-time use, BRA is subject to debate, suffers from a number of limitations, and currently is still under development. The use of formal, systematic structured approaches to BRA for regulatory decision-making and quantitative methods to support BRA during the product lifecycle is a standard practice in medicine that is subject to continuous improvement and modernization, not only in methodology but also in cooperation between organizations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=benefit-risk%20assessment" title="benefit-risk assessment">benefit-risk assessment</a>, <a href="https://publications.waset.org/abstracts/search?q=benefit-risk%20profile" title=" benefit-risk profile"> benefit-risk profile</a>, <a href="https://publications.waset.org/abstracts/search?q=product%20lifecycle" title=" product lifecycle"> product lifecycle</a>, <a href="https://publications.waset.org/abstracts/search?q=quantitative%20methods" title=" quantitative methods"> quantitative methods</a>, <a href="https://publications.waset.org/abstracts/search?q=structured%20approaches" title=" structured approaches"> structured approaches</a> </p> <a href="https://publications.waset.org/abstracts/102835/a-review-of-benefit-risk-assessment-over-the-product-lifecycle" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/102835.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">23</span> Population Dynamics of Early Oak Defoliators in Correlation with Micro-climatic Temperature Conditions in Kragujevac Area in Serbia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Miroslava%20Markovi%C4%87">Miroslava Marković</a>, <a href="https://publications.waset.org/abstracts/search?q=Renata%20Gagi%C4%87"> Renata Gagić</a>, <a href="https://publications.waset.org/abstracts/search?q=Serdar"> Serdar</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Lu%C4%8Di%C4%87"> Aleksandar Lučić</a>, <a href="https://publications.waset.org/abstracts/search?q=Ljubinko%20Rakonjac"> Ljubinko Rakonjac</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Forest dieback that comes in waves since the early 20th century has lately grown into an epidemic, in particular in oak stands. For this reason, research was conducted of the population dynamics of early oak defoliators, which represent a grave danger in oak stands due to their gradogenic attributes. The research was carried out over a 5-year period in oak forests in the area of forest administrations Kragujevac and Gornji Milanovac. The samples used in the research were collected from bottom branches, where Geometridae were found in the largest numbers, as well as from the mid and upper parts of the crowns, where other species were found. Population levels of these pests were presented in laboratory conditions on winter branch samples and in newly foliated stands on site, depending on the basic parameters of the climatic conditions. The greatest deviation of the population level of early oak defoliators was noted in 2018 on all 6 presented localities through the analysis of winter branches and the analysis of their presence in newly foliated stands on site, and it was followed by the highest average air temperature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=defoliators" title="defoliators">defoliators</a>, <a href="https://publications.waset.org/abstracts/search?q=oak" title=" oak"> oak</a>, <a href="https://publications.waset.org/abstracts/search?q=population%20level" title=" population level"> population level</a>, <a href="https://publications.waset.org/abstracts/search?q=population%20dynamics" title=" population dynamics"> population dynamics</a> </p> <a href="https://publications.waset.org/abstracts/159565/population-dynamics-of-early-oak-defoliators-in-correlation-with-micro-climatic-temperature-conditions-in-kragujevac-area-in-serbia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159565.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">96</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> Biomimetics and Additive Manufacturing for Industrial Design Innovation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Axel%20Thallemer">Axel Thallemer</a>, <a href="https://publications.waset.org/abstracts/search?q=Martin%20Danzer"> Martin Danzer</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominik%20Diensthuber"> Dominik Diensthuber</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Kostadinov"> Aleksandar Kostadinov</a>, <a href="https://publications.waset.org/abstracts/search?q=Bernhard%20Rogler"> Bernhard Rogler</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nature has always inspired the creative mind, to a lesser or greater extent. Introduced around the 1950s, Biomimetics served as a systematic method to treat the natural world as a ‘pattern book’ for technical solutions with the aim to create innovative products. Unfortunately, this technique is prone to failure when performed as a mere reverse engineering of a natural system or appearance. Contrary to that, a solution which looks at the principles of a natural design, promises a better outcome. One such example is the here presented case study, which shows the design process of three distinctive grippers. The devices have biomimetic properties on two levels. Firstly, they use a kinematic chain found in beaks and secondly, they have a biomimetic structural geometry, which was realized using additive manufacturing. In a next step, the manufacturing method was evaluated to estimate its efficiency for commercial production. The results show that the fabrication procedure is still in its early stage and thus it is not able to guarantee satisfactory results. To summarize the study, we claim that a novel solution can be derived using principles from nature, however, for the solution to be actualized successfully, there are parameters which are beyond reach for designers. Nonetheless, industrial designers can contribute to product innovation using biomimetics. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomimetics" title="biomimetics">biomimetics</a>, <a href="https://publications.waset.org/abstracts/search?q=innovation" title=" innovation"> innovation</a>, <a href="https://publications.waset.org/abstracts/search?q=design%20process" title=" design process"> design process</a>, <a href="https://publications.waset.org/abstracts/search?q=additive%20manufacturing" title=" additive manufacturing"> additive manufacturing</a> </p> <a href="https://publications.waset.org/abstracts/84511/biomimetics-and-additive-manufacturing-for-industrial-design-innovation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84511.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">191</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> Chromatographic Lipophilicity Determination of Newly Synthesized Steroid Derivatives for Further Biological Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milica%20Z.%20Karadzic">Milica Z. Karadzic</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20R.%20Jevric"> Lidija R. Jevric</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac-Kuzmanovic"> Sanja Podunavac-Kuzmanovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Z.%20Kovacevic"> Strahinja Z. Kovacevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Anamarija%20I.%20Mandic"> Anamarija I. Mandic</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Penov-Gasi"> Katarina Penov-Gasi</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20R.%20Nikolic"> Andrea R. Nikolic</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20M.%20Okljesa"> Aleksandar M. Okljesa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, a set of 29 newly synthesized steroid derivatives were investigated using reversed-phase high-performance liquid chromatography (RP-HPLC) as a first step in preselection of drug candidates. This analysis presents an experimental determination of chromatographic lipophilicity, and it was conducted to obtain physicochemical characterization of these molecules. As the most widely used bonded phases in RP-HPLC, octadecyl (C18) and octyl (C8) were used. Binary mixtures of water and acetonitrile or methanol were used as mobile phases. Obtained results were expressed as retention factor values logk and they were correlated with logP values. The results showed that both columns provide good estimations of the chromatographic lipophilicity of the molecules included in this study. This analysis was conducted in order to characterize newly synthesized steroid derivatives for further investigation regarding their antiproliferative and antimicrobial activity. This article is based upon work from COST Action (CM1306), supported by COST (European Cooperation in Science and Technology). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antiproliferative%20activity" title="antiproliferative activity">antiproliferative activity</a>, <a href="https://publications.waset.org/abstracts/search?q=chromatographic%20lipophilicity" title=" chromatographic lipophilicity"> chromatographic lipophilicity</a>, <a href="https://publications.waset.org/abstracts/search?q=liquid%20chromatography" title=" liquid chromatography"> liquid chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a> </p> <a href="https://publications.waset.org/abstracts/49454/chromatographic-lipophilicity-determination-of-newly-synthesized-steroid-derivatives-for-further-biological-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/49454.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">291</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Factors Associated with Cytomegalovirus Infection: A Prospective Single Centre Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marko%20Jankovic">Marko Jankovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandra%20Knezevic"> Aleksandra Knezevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Maja%20Cupic"> Maja Cupic</a>, <a href="https://publications.waset.org/abstracts/search?q=Dragana%20Vujic"> Dragana Vujic</a>, <a href="https://publications.waset.org/abstracts/search?q=Zeljko%20Zecevic"> Zeljko Zecevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Borko%20Gobeljic"> Borko Gobeljic</a>, <a href="https://publications.waset.org/abstracts/search?q=Marija%20Simic"> Marija Simic</a>, <a href="https://publications.waset.org/abstracts/search?q=Tanja%20Jovanovic"> Tanja Jovanovic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The human cytomegalovirus (CMV) is a notorious pathogen in the pediatric transplant setting. Although studies on factors in complicity with CMV infection abound, the role of age, gender, allogeneic hematopoietic stem cell transplantation (alloHSCT) modality, and underlying disease as regards CMV infection and viral load in children are poorly explored. We examined the significance of various factors related to the risk of CMV infection and viral load in Serbian children and adolescents undergoing alloHSCT. This was a prospective single centre study of thirty two pediatric patients in receipt of alloHSCT for various malignant and non-malignant disorders. Screening for active viral infection was performed by regular weekly monitoring. The Real-Time PCR method was used for CMV DNA detection and quantitation. Statistical analysis was performed using the IBM SPSS Statistics v20 software. Chi-square test was used to evaluate categorical variables. Comparison between scalar and nominal data was done by Wilcoxon-Mann-Whitney test. Pearson correlation was applied for studying the association between patient age and viral load. CMV was detected in 23 (71.9%) patients. Infection occurred significantly more often (p=0.015) in patients with haploidentical donors. The opposite was noted for matched sibling grafts (p=0.006). The viral load was higher in females (p=0.041) and children in the aftermath of alloHSCT with malignant diseases (p=0.019). There was no significant relationship between the viral infection dynamics and overt medical consequences. This is the first study of risk factors for CMV infection in Serbian pediatric alloHSCT patients. Transplanted patients presented with a high incidence of CMV viremia. The HLA compatibility of donated graft is associated with the frequency of CMV positive events. Age, gender, underlying disease, and medically relevant events were not conducive to occurrences of viremia. Notably, substantial viral burdens were evidenced in females and patients with neoplastic diseases. Studies comprising larger populations are clearly needed to scrutinize current results. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=allogeneic%20hematopoietic%20stem%20cell%20transplantation" title="allogeneic hematopoietic stem cell transplantation">allogeneic hematopoietic stem cell transplantation</a>, <a href="https://publications.waset.org/abstracts/search?q=children" title=" children"> children</a>, <a href="https://publications.waset.org/abstracts/search?q=cytomegalovirus" title=" cytomegalovirus"> cytomegalovirus</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title=" risk factors"> risk factors</a>, <a href="https://publications.waset.org/abstracts/search?q=viral%20load" title=" viral load"> viral load</a> </p> <a href="https://publications.waset.org/abstracts/125519/factors-associated-with-cytomegalovirus-infection-a-prospective-single-centre-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/125519.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">160</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> Microbiological Activity and Molecular Docking Study of Selected Steroid Derivatives of Biomedical Importance</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milica%20Karadzic">Milica Karadzic</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20Jevric"> Lidija Jevric</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac-Kuzmanovic"> Sanja Podunavac-Kuzmanovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Kovacevic"> Strahinja Kovacevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Sinisa%20Markov"> Sinisa Markov</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Okljesa"> Aleksandar Okljesa</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Nikolic"> Andrea Nikolic</a>, <a href="https://publications.waset.org/abstracts/search?q=Marija%20Sakac"> Marija Sakac</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Penov%20Gasi"> Katarina Penov Gasi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study considered the microbiological activity determination and molecular docking study for selected steroid derivatives of biomedical importance. Minimal inhibitory concentration (MIC) was determined for steroid derivatives against Staphylococcus aureus using macrodilution method. Some of the investigated steroid derivatives express bacteriostatic effect against Staphylococcus aureus. Molecular docking approaches are the most widely used techniques for predicting the binding mode of a ligand. Molecular docking study was done for steroid derivatives for androgen receptor negative prostate cancer cell line (PC-3) toward Human Cytochrome P450 CYP17A1. The molecules that had the smallest experimental IC50 values confirmed their ability to dock into active place using suitable molecular docking procedure. The binding disposition of those molecules was thoroughly investigated. Microbiological analysis and molecular docking study were conducted with aim to additionally characterize selected steroid derivatives for future investigation regarding their biological activity and to estimate the binding-affinities of investigated derivatives. This article is based upon work from COST Action (TD1305), supported by COST (European Cooperation and Science and Technology). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=binding%20affinity" title="binding affinity">binding affinity</a>, <a href="https://publications.waset.org/abstracts/search?q=minimal%20inhibitory%20concentration" title=" minimal inhibitory concentration"> minimal inhibitory concentration</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20docking" title=" molecular docking"> molecular docking</a>, <a href="https://publications.waset.org/abstracts/search?q=pc-3%20cell%20line" title=" pc-3 cell line"> pc-3 cell line</a>, <a href="https://publications.waset.org/abstracts/search?q=staphylococcus%20aureus" title=" staphylococcus aureus"> staphylococcus aureus</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a> </p> <a href="https://publications.waset.org/abstracts/60204/microbiological-activity-and-molecular-docking-study-of-selected-steroid-derivatives-of-biomedical-importance" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60204.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">366</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> The Influence of Gender on Itraconazole Pharmacokinetic Parameters in Healthy Adults</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milijana%20N.%20Miljkovic">Milijana N. Miljkovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Viktorija%20M.%20Dragojevic-Simic"> Viktorija M. Dragojevic-Simic</a>, <a href="https://publications.waset.org/abstracts/search?q=Nemanja%20K.%20Rancic"> Nemanja K. Rancic</a>, <a href="https://publications.waset.org/abstracts/search?q=Vesna%20M.%20Jacevic"> Vesna M. Jacevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Snezana%20B.%20Djordjevic"> Snezana B. Djordjevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Momir%20M.%20Mikov"> Momir M. Mikov</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandra%20M.%20Kovacevic"> Aleksandra M. Kovacevic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Itraconazole (ITZ) is a weak base and extremely lipophilic compound, with water solubility as a rate-limiting step in its absorption from the gastrointestinal tract. Its absolute bioavailability, about 55%, is maximal when its oral formulation, capsules, are taken immediately after a full meal. Peak plasma concentrations (Cmax) are reached within 2 to 5 hrs after their administration. ITZ undergoes extensive hepatic metabolism by human CYP3A4 isoenzyme and more than 30 different metabolites have been identified. One of the main ones is hydroxyitraconazole (HITZ), in which plasma concentrations are almost twice higher than those of ITZ. Gender differences in drug PK (Pharmacokinetics) have already been recognized, but variations in metabolism are believed to be their major cause. The aim of the study was to investigate the influence of gender on ITZ PK parameters after administration of oral capsule formulation, following 100 mg single dosing in healthy adult volunteers under fed conditions. The single-center, open-label PK study was performed. PK analyses included PK parameters obtained after a single 100 mg dose administration of itraconazole capsules to 48 females and 66 males. Blood samples were collected at pre-dose and up to 72.0 h after administration (1.0, 2.0, 3.0, 3.5, 4.0, 4.5, 5.0, 5.5, 6.0, 7.0, 9.0, 12.0, 24.0, 36.0 and 72.0 hrs). The calculated pharmacokinetic parameters, based on the plasma concentrations of itraconazole and hydroxyitraconazole, were Cmax, AUClast, and AUCtot. Plasma concentrations of ITZ and HITZ were determined using a validated liquid chromatographic method with mass spectrometric detection, while pharmacokinetic parameters were estimated using non-compartmental methods. The pharmacokinetic analyses were performed using Kinetica software version 5.0. The mean value of ITZ Cmaxmen was 74.79 ng/ml, and Cmaxwomen was 51.291 ng/ml (independent samples test; p = 0.005). Hydroxyitraconazole had a mean value of Cmaxmen 106.37 ng/ml, and the mean value Cmaxwomen was 70.05 ng/ml. Women had, on average, lower AUClast and Cmax than men. AUClastmen for ITZ was 736.02 ng/mL*h and AUClastwomen was 566.62 ng/mL*h, while AUClastmen for HITZ was 1154.80 was ng/mL*h and AUClastwomen for HITZ was 708.12 ng/mL*h (independent samples test; p = 0.033). The mean values of ITZ AUCtotmen were 884.73 ng/mL*h and AUCtotwomen was 685.10 ng/mL*h. AUCtotmen for HITZ was 1290.41 ng/mL*h, while AUCtotwomen for HIZT was 788.60 ng/mL*h (p < 0.001). The results could point out to lower oral bioavailability of ITZ in women, since values of Cmax, AUClast, and AUCtot of both ITZ and HITZ were significantly lower in women than in men, respectively. The reason may be higher expression and activity of CYP3A4 in women than in men, but there also may be differences in other PK parameters. High variability of both ITZ and HITZ concentrations in both genders confirmed that ITZ is a highly variable drug. Further examinations of its PK are needed to justify strategies for therapeutic drug monitoring in patients treated by this antifungal agent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=itraconazole" title="itraconazole">itraconazole</a>, <a href="https://publications.waset.org/abstracts/search?q=gender" title=" gender"> gender</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyitraconazole" title=" hydroxyitraconazole"> hydroxyitraconazole</a>, <a href="https://publications.waset.org/abstracts/search?q=pharmacokinetics" title=" pharmacokinetics"> pharmacokinetics</a> </p> <a href="https://publications.waset.org/abstracts/117538/the-influence-of-gender-on-itraconazole-pharmacokinetic-parameters-in-healthy-adults" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/117538.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">137</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Non-Linear Assessment of Chromatographic Lipophilicity and Model Ranking of Newly Synthesized Steroid Derivatives</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milica%20Karadzic">Milica Karadzic</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20Jevric"> Lidija Jevric</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac-Kuzmanovic"> Sanja Podunavac-Kuzmanovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Kovacevic"> Strahinja Kovacevic</a>, <a href="https://publications.waset.org/abstracts/search?q=Anamarija%20Mandic"> Anamarija Mandic</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Penov%20Gasi"> Katarina Penov Gasi</a>, <a href="https://publications.waset.org/abstracts/search?q=Marija%20Sakac"> Marija Sakac</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Okljesa"> Aleksandar Okljesa</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Nikolic"> Andrea Nikolic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present paper deals with chromatographic lipophilicity prediction of newly synthesized steroid derivatives. The prediction was achieved using in silico generated molecular descriptors and quantitative structure-retention relationship (QSRR) methodology with the artificial neural networks (ANN) approach. Chromatographic lipophilicity of the investigated compounds was expressed as retention factor value logk. For QSRR modeling, a feedforward back-propagation ANN with gradient descent learning algorithm was applied. Using the novel sum of ranking differences (SRD) method generated ANN models were ranked. The aim was to distinguish the most consistent QSRR model that can be found, and similarity or dissimilarity between the models that could be noticed. In this study, SRD was performed with average values of retention factor value logk as reference values. An excellent correlation between experimentally observed retention factor value logk and values predicted by the ANN was obtained with a correlation coefficient higher than 0.9890. Statistical results show that the established ANN models can be applied for required purpose. This article is based upon work from COST Action (TD1305), supported by COST (European Cooperation in Science and Technology). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20neural%20networks" title="artificial neural networks">artificial neural networks</a>, <a href="https://publications.waset.org/abstracts/search?q=liquid%20chromatography" title=" liquid chromatography"> liquid chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20descriptors" title=" molecular descriptors"> molecular descriptors</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a>, <a href="https://publications.waset.org/abstracts/search?q=sum%20of%20ranking%20differences" title=" sum of ranking differences"> sum of ranking differences</a> </p> <a href="https://publications.waset.org/abstracts/50587/non-linear-assessment-of-chromatographic-lipophilicity-and-model-ranking-of-newly-synthesized-steroid-derivatives" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50587.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">319</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> Conceptual Solution and Thermal Analysis of the Final Cooling Process of Biscuits in One Confectionary Factory in Serbia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Du%C5%A1ko%20Salemovi%C4%87">Duško Salemović</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Dedi%C4%87"> Aleksandar Dedić</a>, <a href="https://publications.waset.org/abstracts/search?q=Matilda%20Lazi%C4%87"> Matilda Lazić</a>, <a href="https://publications.waset.org/abstracts/search?q=Dragan%20Halas"> Dragan Halas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper presents the conceptual solution for the final cooling of the chocolate dressing of biscuits in one confectionary factory in Serbia. The proposed concept solution was derived from the desired technological process of final cooling of biscuits and the required process parameters that were to be achieved, and which were an integral part of the project task. The desired process parameters for achieving proper hardening and coating formation are the exchanged amount of heat in the time unit between the two media (air and chocolate dressing), the speed of air inside the tunnel cooler, and the surface of all biscuits in contact with the air. These parameters were calculated in the paper. The final cooling of chocolate dressing on biscuits could be optimized by changing process parameters and dimensions of the tunnel cooler and looking for the appropriate values for them. The accurate temperature predictions and fluid flow analysis could be conducted by using heat balance and flow balance equations, having in mind the theory of similarity. Furthermore, some parameters were adopted from previous technology processes, such as the inlet temperature of biscuits and input air temperature. A thermal calculation was carried out, and it was demonstrated that the percentage error between the contact surface of the air and the chocolate biscuit topping, which is obtained from the heat balance and geometrically through the proposed conceptual solution, does not exceed 0.67%, which is a very good agreement. This enabled the quality of the cooling process of chocolate dressing applied on the biscuit and the hardness of its coating. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chocolate%20dressing" title="chocolate dressing">chocolate dressing</a>, <a href="https://publications.waset.org/abstracts/search?q=air" title=" air"> air</a>, <a href="https://publications.waset.org/abstracts/search?q=cooling" title=" cooling"> cooling</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20balance" title=" heat balance"> heat balance</a> </p> <a href="https://publications.waset.org/abstracts/176788/conceptual-solution-and-thermal-analysis-of-the-final-cooling-process-of-biscuits-in-one-confectionary-factory-in-serbia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/176788.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">79</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Non-Linear Assessment of Chromatographic Lipophilicity of Selected Steroid Derivatives</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milica%20Karad%C5%BEi%C4%87">Milica Karadžić</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20Jevri%C4%87"> Lidija Jevrić</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac-Kuzmanovi%C4%87"> Sanja Podunavac-Kuzmanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Kova%C4%8Devi%C4%87"> Strahinja Kovačević</a>, <a href="https://publications.waset.org/abstracts/search?q=Anamarija%20Mandi%C4%87"> Anamarija Mandić</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Oklje%C5%A1a"> Aleksandar Oklješa</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Nikoli%C4%87"> Andrea Nikolić</a>, <a href="https://publications.waset.org/abstracts/search?q=Marija%20Saka%C4%8D"> Marija Sakač</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Penov%20Ga%C5%A1i"> Katarina Penov Gaši</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Using chemometric approach, the relationships between the chromatographic lipophilicity and in silico molecular descriptors for twenty-nine selected steroid derivatives were studied. The chromatographic lipophilicity was predicted using artificial neural networks (ANNs) method. The most important in silico molecular descriptors were selected applying stepwise selection (SS) paired with partial least squares (PLS) method. Molecular descriptors with satisfactory variable importance in projection (VIP) values were selected for ANN modeling. The usefulness of generated models was confirmed by detailed statistical validation. High agreement between experimental and predicted values indicated that obtained models have good quality and high predictive ability. Global sensitivity analysis (GSA) confirmed the importance of each molecular descriptor used as an input variable. High-quality networks indicate a strong non-linear relationship between chromatographic lipophilicity and used in silico molecular descriptors. Applying selected molecular descriptors and generated ANNs the good prediction of chromatographic lipophilicity of the studied steroid derivatives can be obtained. This article is based upon work from COST Actions (CM1306 and CA15222), supported by COST (European Cooperation and Science and Technology). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20neural%20networks" title="artificial neural networks">artificial neural networks</a>, <a href="https://publications.waset.org/abstracts/search?q=chemometrics" title=" chemometrics"> chemometrics</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20sensitivity%20analysis" title=" global sensitivity analysis"> global sensitivity analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=liquid%20chromatography" title=" liquid chromatography"> liquid chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a> </p> <a href="https://publications.waset.org/abstracts/60203/non-linear-assessment-of-chromatographic-lipophilicity-of-selected-steroid-derivatives" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60203.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">345</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Evaluation of Newly Synthesized Steroid Derivatives Using In silico Molecular Descriptors and Chemometric Techniques</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milica%20%C5%BD.%20Karad%C5%BEi%C4%87">Milica Ž. Karadžić</a>, <a href="https://publications.waset.org/abstracts/search?q=Lidija%20R.%20Jevri%C4%87"> Lidija R. Jevrić</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Podunavac-Kuzmanovi%C4%87"> Sanja Podunavac-Kuzmanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Strahinja%20Z.%20Kova%C4%8Devi%C4%87"> Strahinja Z. Kovačević</a>, <a href="https://publications.waset.org/abstracts/search?q=Anamarija%20I.%20Mandi%C4%87"> Anamarija I. Mandić</a>, <a href="https://publications.waset.org/abstracts/search?q=Katarina%20Penov-Ga%C5%A1i"> Katarina Penov-Gaši</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20R.%20Nikoli%C4%87"> Andrea R. Nikolić</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20M.%20Oklje%C5%A1a"> Aleksandar M. Oklješa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study considered selection of the in silico molecular descriptors and the models for newly synthesized steroid derivatives description and their characterization using chemometric techniques. Multiple linear regression (MLR) models were established and gave the best molecular descriptors for quantitative structure-retention relationship (QSRR) modeling of the retention of the investigated molecules. MLR models were without multicollinearity among the selected molecular descriptors according to the variance inflation factor (VIF) values. Used molecular descriptors were ranked using generalized pair correlation method (GPCM). In this method, the significant difference between independent variables can be noticed regardless almost equal correlation between dependent variable. Generated MLR models were statistically and cross-validated and the best models were kept. Models were ranked using sum of ranking differences (SRD) method. According to this method, the most consistent QSRR model can be found and similarity or dissimilarity between the models could be noticed. In this study, SRD was performed using average values of experimentally observed data as a golden standard. Chemometric analysis was conducted in order to characterize newly synthesized steroid derivatives for further investigation regarding their potential biological activity and further synthesis. This article is based upon work from COST Action (CM1105), supported by COST (European Cooperation in Science and Technology). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=generalized%20pair%20correlation%20method" title="generalized pair correlation method">generalized pair correlation method</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20descriptors" title=" molecular descriptors"> molecular descriptors</a>, <a href="https://publications.waset.org/abstracts/search?q=regression%20analysis" title=" regression analysis"> regression analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=steroids" title=" steroids"> steroids</a>, <a href="https://publications.waset.org/abstracts/search?q=sum%20of%20ranking%20differences" title=" sum of ranking differences"> sum of ranking differences</a> </p> <a href="https://publications.waset.org/abstracts/49456/evaluation-of-newly-synthesized-steroid-derivatives-using-in-silico-molecular-descriptors-and-chemometric-techniques" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/49456.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">347</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Antifeedant Activity of Plant Extracts on the Spongy Moth (Lymantria dispar) Larvae</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jovana%20M.%20%C4%86irkovi%C4%87">Jovana M. Ćirković</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20M.%20Radojkovi%C4%87"> Aleksandar M. Radojković</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Z.%20Pera%C4%87"> Sanja Z. Perać</a>, <a href="https://publications.waset.org/abstracts/search?q=Jelena%20N.%20Jovanovi%C4%87"> Jelena N. Jovanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Zorica%20M.%20Brankovi%C4%87"> Zorica M. Branković</a>, <a href="https://publications.waset.org/abstracts/search?q=Slobodan%20D.%20Milanovi%C4%87"> Slobodan D. Milanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Ivan%20Lj.%20Milenkovi%C4%87"> Ivan Lj. Milenković</a>, <a href="https://publications.waset.org/abstracts/search?q=Jovan%20N.%20Dobrosavljevi%C4%87"> Jovan N. Dobrosavljević</a>, <a href="https://publications.waset.org/abstracts/search?q=Nemanja%20V.%20Simovi%C4%87"> Nemanja V. Simović</a>, <a href="https://publications.waset.org/abstracts/search?q=Vanja%20M.%20Tadi%C4%87"> Vanja M. Tadić</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20R.%20%C5%BDugi%C4%87"> Ana R. Žugić</a>, <a href="https://publications.waset.org/abstracts/search?q=Goran%20O.%20Brankovi%C4%87"> Goran O. Branković</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The protection of forests is a national interest and of strategic importance in every country. The spongy moth (Lymantria dispar) is a damaging invasive pest that can weaken and destroy trees by defoliating them. Chemical pesticides commonly used to protect forests against spongy moths not only have a negative impact on terrestrial and aquatic organisms/ecosystems but also often fail to provide significant protection. Therefore, many eco-friendly alternatives have been considered. Within this research, a new biopesticide was developed based on the method of nanoencapsulation of plant extracts in a biopolymer matrix, which provides a slow release of the active components during a substantial time period. The antifeedant activity of plant extracts of common (Fraxinus excelsior L.), manna (F. ornus L.) ash tree, and the tree of heaven Ailanthus altissima (Mill.) was tested on the spongy moth (Lymantria dispar L, 1758) larvae. To test the antifeedant activity of these compounds, the choice and non-choice tests in laboratory conditions for different plant extract concentrations (0.01, 0.1, 0.5, and 1 % v/v) were carried out. In both cases, the best results showed formulations based on the tree of heaven and common ash for the concentration of 1%, with deterioration indices of 163 and 132, respectively. The main benefit of these formulations is their versatility, effectiveness, prolonged effect, and because they are completely environmentally acceptable. Therefore, they can be considered for suppression of the spongy moth in forest ecosystems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ailanthus%20altissima%20%28Mill.%29" title="Ailanthus altissima (Mill.)">Ailanthus altissima (Mill.)</a>, <a href="https://publications.waset.org/abstracts/search?q=Fraxinus%20excelsior%20L." title=" Fraxinus excelsior L."> Fraxinus excelsior L.</a>, <a href="https://publications.waset.org/abstracts/search?q=encapsulation" title=" encapsulation"> encapsulation</a>, <a href="https://publications.waset.org/abstracts/search?q=Lymantria%20dispar" title=" Lymantria dispar"> Lymantria dispar</a> </p> <a href="https://publications.waset.org/abstracts/171972/antifeedant-activity-of-plant-extracts-on-the-spongy-moth-lymantria-dispar-larvae" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171972.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">77</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Encapsulated Western Red Cedar (Thuja Plicata) Essential Oil as a Prospective Biopesticide against Phytophthora Pathogens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20M.%20Radojkovi%C4%87">Aleksandar M. Radojković</a>, <a href="https://publications.waset.org/abstracts/search?q=Jovana%20M.%20%C4%86irkovi%C4%87"> Jovana M. Ćirković</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanja%20Z.%20Pera%C4%87"> Sanja Z. Perać</a>, <a href="https://publications.waset.org/abstracts/search?q=Jelena%20N.%20Jovanovi%C4%87"> Jelena N. Jovanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Zorica%20M.%20Brankovi%C4%87"> Zorica M. Branković</a>, <a href="https://publications.waset.org/abstracts/search?q=Slobodan%20D.%20Milanovi%C4%87"> Slobodan D. Milanović</a>, <a href="https://publications.waset.org/abstracts/search?q=Ivan%20Lj.%20Milenkovi%C4%87"> Ivan Lj. Milenković</a>, <a href="https://publications.waset.org/abstracts/search?q=Jovan%20N.%20Dobrosavljevi%C4%87"> Jovan N. Dobrosavljević</a>, <a href="https://publications.waset.org/abstracts/search?q=Nemanja%20V.%20Simovi%C4%87"> Nemanja V. Simović</a>, <a href="https://publications.waset.org/abstracts/search?q=Vanja%20M.%20Tadi%C4%87"> Vanja M. Tadić</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20R.%20%C5%BDugi%C4%87"> Ana R. Žugić</a>, <a href="https://publications.waset.org/abstracts/search?q=Goran%20O.%20Brankovi%C4%87"> Goran O. Branković</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In many parts of the world, various Phytophthora species pose a serious threat to forests and crops. With the rapidly growing international trade in plants and the ongoing impacts of climate change, the harmful effects of plant pathogens of the genus Phytophthora are increasing, damaging the biodiversity and sustainability of forest ecosystems. This genus is one of the most destructive plant pathogens, causing the majority of fine root (66%) and collar rot diseases (90%) of woody plant species worldwide. Eco-friendly biopesticides, based on plant-derived products, such as essential oils (EOs), are one of the promising solutions to this problem. In this study, among three different EOs investigated (Chamaecyparis lawsoniana (A. Murr.) Parl., Thuja plicata Donn ex D.Don and Juniperus communis L.), western red cedar (Thuja plicata) essential oil almost completely inhibited the growth of three Phytophthora species (P. plurivora Jung and Burgess, P. quercina Jung, and P. ×cambivora (Petri) Buisman) during seven days of exposure for the EO concentrations of 0.1% and 0.5% (v/v). To prolong the inhibiting effect, Thuja plicata EO was encapsulated into a biopolymer matrix consisting of a chitosan-gelatin mixture to form a water-in-oil emulsion. This approach allowed the prolonged effect of the essential oil by its slow release from the biopolymer matrix and protection of the active components from atmospheric influences. Thus, it was demonstrated that encapsulated Thuja plicata EO consisting of sustainable bioproducts is efficient in controlling of Phytophthora species and can be considered a means of protection in natural and semi-natural ecosystems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=emulsions" title="emulsions">emulsions</a>, <a href="https://publications.waset.org/abstracts/search?q=essential%20oils" title=" essential oils"> essential oils</a>, <a href="https://publications.waset.org/abstracts/search?q=phytophthora" title=" phytophthora"> phytophthora</a>, <a href="https://publications.waset.org/abstracts/search?q=thuja%20plicata" title=" thuja plicata"> thuja plicata</a> </p> <a href="https://publications.waset.org/abstracts/171742/encapsulated-western-red-cedar-thuja-plicata-essential-oil-as-a-prospective-biopesticide-against-phytophthora-pathogens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171742.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">92</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Genuine Domestic Change or Fake Compliance: Political Pervasiveness in the Serbian Media</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksandra%20Dragojlov">Aleksandra Dragojlov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Since the election of Aleksandar Vučić and the Progressives, Serbia has witnessed a slow decline in media freedom, which has been worse than in the 1990s. Although the government adopted a package of three laws in August 2014 to bring the media landscape up to European standards, the implementation of the laws has been limited and marginal, with the progressives engaging in fake compliance. The adoption of the new media strategy for 2020-2025 in 2020 has not led to genuine domestic reform and compliance with EU conditionality. In fact, the EU Commission and journalists’ associations in Serbia have criticised the decline in Serbia’s media freedom citing continued attacks on journalists and indirect political and economic control through advertising and project co-financing, which continue to be features of the Serbian media landscape. In the absence of clear and credible EU conditionality, the decline of media freedom is in the eye of the beholder, where the gap between public engagements with Serbian politicians and the critical stance of progress reports regarding the degradation of the media have enabled Serbian elites to exploit this ambiguity to continue their strategy of fake compliance vis-a-vis rule of law. This study used a mixed methods approach combining both primary and secondary sources with those semi-structured interviews via Zoom, email, and in person with EU and Serbian officials and journalists. Our findings add to the studies where the lack of clear and credible conditionality has allowed Serbia politicians to exploit them in a manner that would suit their own interests, finding new means to retain their control over the media. We argued and concluded that it is this discrepancy between public engagements with Serbia and the progress reports in the area of freedom of expression that has not led to genuine domestic media reforms in Serbia and instead allowed Serbian elites to engage in a strategy of fake and even non-compliance towards media freedom conditionality. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=media%20freedom" title="media freedom">media freedom</a>, <a href="https://publications.waset.org/abstracts/search?q=EU%20conditionality" title=" EU conditionality"> EU conditionality</a>, <a href="https://publications.waset.org/abstracts/search?q=Serbia" title=" Serbia"> Serbia</a>, <a href="https://publications.waset.org/abstracts/search?q=fake%20compliance" title=" fake compliance"> fake compliance</a>, <a href="https://publications.waset.org/abstracts/search?q=EU%20integration" title=" EU integration"> EU integration</a>, <a href="https://publications.waset.org/abstracts/search?q=Chapter%2023" title=" Chapter 23"> Chapter 23</a>, <a href="https://publications.waset.org/abstracts/search?q=justice%20and%20fundamental%20rights" title=" justice and fundamental rights"> justice and fundamental rights</a> </p> <a href="https://publications.waset.org/abstracts/158883/genuine-domestic-change-or-fake-compliance-political-pervasiveness-in-the-serbian-media" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158883.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Biological Control of Woolly Apple Aphid, Eriosoma Lanigerum (Hausmann) in the Nursery Production of Spruce</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Snezana%20Rajkovic">Snezana Rajkovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Miroslava%20Markovic"> Miroslava Markovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Ljubinko%20Rakonjac"> Ljubinko Rakonjac</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Lucic"> Aleksandar Lucic</a>, <a href="https://publications.waset.org/abstracts/search?q=Radoslav%20Rajkovic"> Radoslav Rajkovic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Woolly apple aphid, Eriosoma lanigerum (Hausmann) is a widely distributed pest of apple trees, especially where its parasites have been killed by insecticides. It can also be found on pear, hawthorn, mountain ash, and elm trees. Relatively small to medium-sized aphids, characterized by a reddish-brown body, a blood-red stain when crushed and a fluffy, flocculent wax covering. Specialized dermal glands produce the characteristic fluffy or powdery wax, which gives E. lanigerum its characteristic 'woolly' appearance. Also, woolly apple aphid is a problemm in nursery production of spure.The experiments were carried out in the nursery “Nevade” in Gornji Milanovac, "Srbijasume" on the spruce seedlings, aged 2 years. In this study, organic insecticide King Bo, aqueous solution (a. i. oxymatrine 0.2% + psoralen 0.4%), manufacturer Beijing Kingbo Biotech Co. Ltd., Beijing, China. extracted from plants and used as pesticides in nursery production were investigated. King Bo, bioinsecticide is manufactured from refined natural herbal extract several wild medicinal plants, such as Sophora flavescens Ait, Veratrum nigrum L, A. Carmichael, etc. Oxymatrine 2.4 SL is a stomach poison that has antifeeding and repellent action. This substance stimulates development and growth in a host plant and also controls the appearance of downy mildew.The trials were set according to instructions of methods-monitoring of changes in the number of larvae and adults compared to before treatment. The treatment plan was made according to fully randomized block design. The experiment was conducted in four repetitions. The basic plot had the area of 25 m2. Phytotoxicity was estimated by PP methods 1/135 (2), the intensity of infection according to Towsend-Heuberger, the efficiency by Abbott, the analysis of variance with Ducan test and PP/181 (2). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioinsecticide" title="bioinsecticide">bioinsecticide</a>, <a href="https://publications.waset.org/abstracts/search?q=efficacy" title=" efficacy"> efficacy</a>, <a href="https://publications.waset.org/abstracts/search?q=nurssery%20production" title=" nurssery production"> nurssery production</a>, <a href="https://publications.waset.org/abstracts/search?q=woolly%20apple%20aphid" title=" woolly apple aphid"> woolly apple aphid</a> </p> <a href="https://publications.waset.org/abstracts/22916/biological-control-of-woolly-apple-aphid-eriosoma-lanigerum-hausmann-in-the-nursery-production-of-spruce" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22916.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">550</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Biopotential of Introduced False Indigo and Albizia’s Weevils in Host Plant Control and Duration of Its Development Stages in Southern Regions of Panonian Basin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Renata%20Gagi%C4%87-Serdar">Renata Gagić-Serdar</a>, <a href="https://publications.waset.org/abstracts/search?q=Miroslava%20Markovic"> Miroslava Markovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Ljubinko%20Rakonjac"> Ljubinko Rakonjac</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Lu%C4%8Di%C4%87"> Aleksandar Lučić</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper present the results of the entomological experimental studies of the biological, ecological, and (bionomic) insect performances, such as seasonal adaptation of introduced monophagous false indigo and albizias weevil’s Acanthoscelides pallidipennis Motschulsky. and Bruchidius terrenus (Sharp), Coleoptera: Chrysomelidae: Bruchinae, to phenological phases of aggressive invasive host plant Amorpha fruticosa L. and Albizia julibrissin (Fabales: Fabaceae) on the territory of Republic of Serbia with special attention on assessing and monitoring of new formed and detected inter species relations between autochthons parasite wasps from fauna (Hymenoptera: Chalcidoidea) and herbaceous seed weevil beetle. During 15 years (2006-2021), on approximately 30 localities, data analyses were done for observed experimental host plants from samples with statistical significance. Status of genera from families Hymenoptera: Chalcidoidea.: Pteromalidae and Eulophidae, after intensive investigations, has been trophicly identified. Recorded seed pest species of A. fruticosa or A. julibrissin (Fabales: Fabaceae) was introduced in Serbia and planted as ornamental trees, they also were put undergo different kinds of laboratory and field research tests during this period in a goal of collecting data about lasting each of develop stage of their seed beetles. Field generations in different stages were also monitored by continuous infested seed collecting and its disection. Established host plant-seed predator linkage was observed in correlation with different environment parameters, especially water level fluctuations in bank corridor formation stands and riparian cultures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=amorpha" title="amorpha">amorpha</a>, <a href="https://publications.waset.org/abstracts/search?q=albizia" title=" albizia"> albizia</a>, <a href="https://publications.waset.org/abstracts/search?q=chalcidoid%20wasp" title=" chalcidoid wasp"> chalcidoid wasp</a>, <a href="https://publications.waset.org/abstracts/search?q=invasiveness" title=" invasiveness"> invasiveness</a>, <a href="https://publications.waset.org/abstracts/search?q=weevils" title=" weevils"> weevils</a> </p> <a href="https://publications.waset.org/abstracts/159564/biopotential-of-introduced-false-indigo-and-albizias-weevils-in-host-plant-control-and-duration-of-its-development-stages-in-southern-regions-of-panonian-basin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159564.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">‹</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Simic&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Aleksandar%20Simic&page=2" rel="next">›</a></li> </ul> </div> </main> <footer> <div 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