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Human Complement Component C5aR1 Antibody (MAB3648) by R&D Systems, Part of Bio-Techne
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data-drupal-link-system-path="node/3421">Transition to GMP </a> <a href="/gmp-products/loa-request" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13326">DMF/LOA Request</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instruments<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/brands/proteinsimple" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3281">ProteinSimple Instruments</a> <a href="/instruments/ice" class="dropdown-item text-wrap" data-drupal-link-system-path="node/256">iCE Maurice</a> <a href="/instruments/imagers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/536">Imagers</a> <a href="/instruments/luminex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/241">Luminex</a> <a href="/instruments/micro-flow-imaging" class="dropdown-item text-wrap" data-drupal-link-system-path="node/526">Micro-Flow Imaging</a> <a href="/instruments/simple-plex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/541">Simple Plex Ella</a> <a href="/instruments/simple-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/521">Simple Western</a> <a href="/instruments/single-cell-dispensers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6361">Single Cell Dispensers</a> <a href="/instruments/single-cell-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/531">Single Cell Western</a> <a href="/instruments" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6731">View All Instruments</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Applications<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/methods/bioprocessing" class="dropdown-item text-wrap">Bioprocessing</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Research Areas<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/research-areas/cell-and-gene-therapy" class="dropdown-item text-wrap" data-drupal-link-system-path="node/51">Cell & Gene Therapy</a> <a href="/applications/immuno-oncology-clinical" class="dropdown-item text-wrap" data-drupal-link-system-path="node/2066">Immuno-Oncology</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-diagnostics" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Diagnostics <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-diagnostics" aria-labelledby="navbarDropdown-diagnostics"> <div class="row"> <div class="col 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aria-expanded="false"> Services <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-services" aria-labelledby="navbarDropdown-services"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Custom Quotes<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/bulk-quotes" class="dropdown-item text-wrap" data-drupal-link-system-path="services/bulk-quotes">Bulk Quote Discounts</a> <a href="/services/custom-formulation" class="dropdown-item text-wrap" data-drupal-link-system-path="services/custom-formulation">Custom Formulation Quotes</a> <a href="/reagents/rnascope-ish-technology/probes/custom" class="dropdown-item text-wrap" data-drupal-link-system-path="node/12571">RNAscope Custom Probe Design Quote</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Custom 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</div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-resources" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Resources <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-resources" aria-labelledby="navbarDropdown-resources"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Product & Instrument Tools<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/resources/cofa-finder-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/cofa-finder-tool">Certificate of Analysis (COA) Finder Tool</a> <a href="/resources/calculators" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7416">Calculators</a> <a href="/resources/flow-cytometry-panel-builder" class="dropdown-item text-wrap" 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</li> <li> <a href="/t/complement-component-c5ar1">Complement Component C5aR1</a> </li> <li> <a href="/t/complement-component-c5ar1/antibodies">Complement Component C5aR1 Antibodies</a> </li> <li> Human Complement Component C5aR1 Antibody (MAB3648) </li> </ol> </nav> </div> </div> </div> <div> <main> <section class="section"> <div> <div id="block-bio-techne-global-content" class="system_main_block"> <div id="product-page-details" data-template_in_use="antibody_template" data-time_total="1.7488069534302" data-time_to_compile="0.20549201965332" data-time_to_build="0.70311498641968" data-time_datapoints="0.84019994735718" data-time_template="-0.84019994735718" data-time_post_epcc="0.908607006073" data-time_epcc="0.84019994735718" data-render_time="Friday 22nd of November 2024 10:32:19 AM" data-fallback="FALSE" data-time_to_process_data="0.30178093910217" class="px-4 container" class="container"> <div id="above-fold-section"> <div class="mb-2 o__product-summary"> <div id="header-subheader" data-section="section-base--header-subheader"> <div class="row" id="pp-page-title-brand-wrapper"> <div class="col-lg-9 col-md-12"> <h1 class="font-weight-bold"> Human Complement Component C5aR1 Antibody </h1> <h2 class="font-weight-normal h4"> R&D Systems, part of Bio-Techne <span id="product-code"> | Catalog # <span class="font-weight-bold">MAB3648</span> </span> </h2> <div id="pp-reviews-citations-row"> <div id="header_left" class="row"> <div id="submit_review_wrapper" class="col-auto d-flex align-self-center"> <div id="submit_review"> <a href="/reviews/MAB3648" class="submit_review" rel="nofollow"> <span class="icon-plus-circle d-none d-lg-inline pr-1"></span> Submit a review </a> </div> </div> <div id="citation_quick_link_wrapper" class="col-auto d-flex align-self-center"> <div id="citation_quicklink"> <a href="#citations" id="citation_count" data-tab="2" class="citations"> <span class="icon-icon-product-citations d-none d-lg-inline pr-1"></span> Citations (4) </a> </div> </div> <div class="col-auto d-flex align-self-center"> <div> <div class="px-0 my-1" id="datasheet-summary-wrapper" data-section="section-base--top-jumplink"> <article class="top-jumplink-wrapper"> <span class="icon-icon-pdf text-error-red"></span> <a href="#product-documents" class="product-documents-top-link" rel="nofollow">Product Datasheet / COA / SDS</a> </article> </div> </div> </div> </div> </div> <div id="new_version_available"> </div> </div> <div class="col-lg-3 col-md-12"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/logos/bio-techne-rnd-systems.svg" alt="R&D Systems, part of Bio-Techne" class="d-flex h-100 w-100"> </div> </div> </div> <div class="row border-top mb-2" id="images-orderdetail-wrapper"> <div class="col-xl-6 mt-2" id="images-wrapper" data-section="image_summary"> <div id="image-tree" data-section="component-product-image-tree" class="vertical lightbox" data-mdb-zoom-effect="true"> <div id="product-image-gallery" class="row"> <div class="col-md-11 border rounded d-flex align-items-center justify-content-center product-image-lightbox"> <div class="text-center my-2" data-brand="rnd"> <img src="https://resources.bio-techne.com/images/products/antibody/Complement_Component_C5a_R1_MAB3648_Block_Neutralize_9166.jpg" alt="N-Acetyl-beta -D-Glucosa-minidase Release Induced by Complement Component C5a and Neutralization by Human Complement Component C5a R1 Antibody." title="N-Acetyl-beta -D-Glucosa-minidase Release Induced by Complement Component C5a and Neutralization by Human Complement Component C5a R1 Antibody." data-caption="Recombinant Human Complement Component C5a (Catalog # <a href="/p/proteins-enzymes/recombinant-human-complement-component-c5a-protein_2037-c5" target="_self">2037-C5</a>) induces N-acetyl-beta -D-glucosa-minidase release in the dibutyryl cyclic-AMP differentiated U937 human histiocytic lymphoma cell line in a dose-dependent manner (orange line). N-Acetyl-beta -D-Glucosaminidase Release elicited by Recombinant Human Complement Component C5a (10 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Complement Component C5a R1 Monoclonal Antibody (Catalog # MAB3648). The ND<sub>50</sub> is typically 2-10 µg/mL in the presence of cytochalasin-B." data-badges='' data-id="0" width="250" height="250" fetchpriority="high" as="image" class="search_result_thumbnail_image active" /> </div> </div> </div> </div> </div> <div class="col-xl-6 mt-2" id="orderdetails-wrapper" data-section="order_detail_block"> <div class="atc-container"> <div class="atc-block" data-type="ds" data-blockid="ProductCart" > <form action="/commerce/addtocart" method="post" class="add-to-cart-block" data-productcode="MAB3648"> <input type="hidden" name="print-quote" class="print-quote-input" value=""> <div class="commerce-atc-full-header atc-header col-four row border-bottom pb-1 m-0"> <div class="commerce-atc-catnum atc-head col-4 col-md-3 font-weight-bold p-0">Catalog #</div> <div class="commerce-atc-availability atc-head col-md-4 p-0 font-weight-bold d-none d-md-block">Availability</div> <div class="commerce-atc-price atc-head col-4 col-md-3 p-0 font-weight-bold">Size / Price</div> <div class="commerce-atc-quantity atc-head col-4 col-3 col-md-2 text-right font-weight-bold p-0">Qty</div> </div> <div class="spinner-border spinner-border-sm mt-3 ml-3" role="status"> <span class="sr-only">Loading...</span> </div> <div class="d-none search-product-mask"> <div id="ProductCart" class="atc-lines"> <div class="commerce-atc-ds-productline productline col-four row my-2 mx-0 text-left" data-catalog="MAB3648" data-hidden=""> <div class="commerce-atc-catnum col-3 col-md-3 pl-0 m-0">MAB3648</div> <div class="commerce-atc-availability col-md-4 pl-0 m-0 d-none d-md-block"> </div> <div class="commerce-atc-price col-4 col-md-3 pl-0 m-0"> </div> <div class="commerce-atc-quantity col-4 col-md-2 text-right px-0 m-0"> </div> </div> <div class="commerce-atc-ds-productline productline col-four row my-2 mx-0 text-left" data-catalog="MAB3648-SP" data-hidden=""> <div class="commerce-atc-catnum col-3 col-md-3 pl-0 m-0">MAB3648-SP</div> <div class="commerce-atc-availability col-md-4 pl-0 m-0 d-none d-md-block"> </div> <div class="commerce-atc-price col-4 col-md-3 pl-0 m-0"> </div> <div class="commerce-atc-quantity col-4 col-md-2 text-right px-0 m-0"> </div> </div> </div> <div class="atc-control ProductCart-control text-right"> <div class="row container d-flex justify-content-end mx-0 mb-3 p-0"> <div class="order-md-last m___button-atc mx-1"> <button type="submit" value="Add To Cart" class="atc-add-button btn a___button-atc m-1 col-xs-4 order-last btn-md-block w-100"> Add To Cart </button> </div> <div class="m___button-atc mx-1"> <a href="" class="atc-print-quote-button btn btn-secondary m-1 col-xs-4 btn-md-block w-100">Print Quote</a> </div> <div class="m___button-atc mx-1"> <a href="/services/bulk-quotes?product_code=MAB3648" class="atc-bulk-button btn btn-secondary m-1 col-xs-4 btn-md-block w-100" rel="nofollow">Bulk Order</a> </div> </div> </div> </div> </form> </div> </div> <div class="atc-container order_detail_wrapper conjugates-and-formulations-wrapper my-2 position-relative"> <div class="button-group text-right pl-2"> <a href="#conjugates-MAB3648" class="btn btn-secondary atc-view-pricing atc-view-pricing-products collapsed text-nowrap mb-2" data-id="conjugates-MAB3648" data-toggle="collapse" aria-expanded="false" aria-controls="conjugates">View Available Conjugates </a> </div> <div id="conjugates-MAB3648" class="conjugates-and-formulations-container collapse position-absolute w-100"> <div class="atc-container border rounded bg-white shadow p-2 mt-1"> <div class="commerce-atc-datasheet atc-block-collapsible" data-type="conjugates_and_formulations" data-blockid="mab3648-conjugate-atc-block"> <div id="mab3648-conjugate-atc-block" class="atc-lines"> <div class="atc-header row pb-1 m-0"> <div class="atc-head col-4 p-0 font-weight-bold d-sm-none d-md-block">Conjugate</div> <div class="atc-head col-4 p-0 font-weight-bold">Catalog #</div> <div class="atc-head col-4"></div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648U" data-titleoverwrite="Alexa Fluor 350"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-350-conjugated-antibody-347214_fab3648u">Alexa Fluor 350</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-350-conjugated-antibody-347214_fab3648u">FAB3648U</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-350-conjugated-antibody-347214_fab3648u" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648V" data-titleoverwrite="Alexa Fluor 405"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-405-conjugated-antibody-347214_fab3648v">Alexa Fluor 405</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-405-conjugated-antibody-347214_fab3648v">FAB3648V</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-405-conjugated-antibody-347214_fab3648v" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648G" data-titleoverwrite="Alexa Fluor 488"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-488-conjugated-antibody-347214_fab3648g">Alexa Fluor 488</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-488-conjugated-antibody-347214_fab3648g">FAB3648G</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-488-conjugated-antibody-347214_fab3648g" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648X" data-titleoverwrite="Alexa Fluor 532"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648x">Alexa Fluor 532</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648x">FAB3648X</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648x" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648T" data-titleoverwrite="Alexa Fluor 594"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-594-conjugated-antibody-347214_fab3648t">Alexa Fluor 594</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-594-conjugated-antibody-347214_fab3648t">FAB3648T</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-594-conjugated-antibody-347214_fab3648t" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648R" data-titleoverwrite="Alexa Fluor 647"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-647-conjugated-antibody-347214_fab3648r">Alexa Fluor 647</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-647-conjugated-antibody-347214_fab3648r">FAB3648R</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-647-conjugated-antibody-347214_fab3648r" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648N" data-titleoverwrite="Alexa Fluor 700"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-700-conjugated-antibody-347214_fab3648n">Alexa Fluor 700</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-700-conjugated-antibody-347214_fab3648n">FAB3648N</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5a-r1-alexa-fluor-700-conjugated-antibody-347214_fab3648n" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648S" data-titleoverwrite="Alexa Fluor 750"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5ar1-alexa-fluor-750-conjugated-antibody-347214_fab3648s">Alexa Fluor 750</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5ar1-alexa-fluor-750-conjugated-antibody-347214_fab3648s">FAB3648S</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5ar1-alexa-fluor-750-conjugated-antibody-347214_fab3648s" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648A" data-titleoverwrite="Allophycocyanin"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5ar1-apc-conjugated-antibody-347214_fab3648a">Allophycocyanin</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5ar1-apc-conjugated-antibody-347214_fab3648a">FAB3648A</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5ar1-apc-conjugated-antibody-347214_fab3648a" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648APCCY7" data-titleoverwrite="Allophycocyanin/Cy7"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648apccy7">Allophycocyanin/Cy7</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648apccy7">FAB3648APCCY7</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648apccy7" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648B" data-titleoverwrite="Biotin"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648b">Biotin</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648b">FAB3648B</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648b" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648CL1" data-titleoverwrite="CoraFluor 1"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648cl1">CoraFluor 1</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648cl1">FAB3648CL1</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648cl1" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648D" data-titleoverwrite="DyLight 350"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648d">DyLight 350</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648d">FAB3648D</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648d" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648E" data-titleoverwrite="DyLight 405"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648e">DyLight 405</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648e">FAB3648E</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648e" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648K" data-titleoverwrite="DyLight 488"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648k">DyLight 488</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648k">FAB3648K</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648k" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648L" data-titleoverwrite="DyLight 550"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648l">DyLight 550</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648l">FAB3648L</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648l" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648M" data-titleoverwrite="DyLight 594"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648m">DyLight 594</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648m">FAB3648M</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648m" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648W" data-titleoverwrite="DyLight 650"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648w">DyLight 650</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648w">FAB3648W</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648w" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648Y" data-titleoverwrite="DyLight 680"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648y">DyLight 680</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648y">FAB3648Y</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648y" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648Z" data-titleoverwrite="DyLight 755"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648z">DyLight 755</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648z">FAB3648Z</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648z" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648F" data-titleoverwrite="Fluorescein"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/human-complement-component-c5ar1-fluorescein-conjugated-antibody-347214_fab3648f">Fluorescein</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5ar1-fluorescein-conjugated-antibody-347214_fab3648f">FAB3648F</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5ar1-fluorescein-conjugated-antibody-347214_fab3648f" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648H" data-titleoverwrite="HRP"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648h">HRP</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648h">FAB3648H</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648h" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648JF525" data-titleoverwrite="Janelia Fluor 525"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf525">Janelia Fluor 525</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf525">FAB3648JF525</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf525" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648I" data-titleoverwrite="Janelia Fluor 549"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648i">Janelia Fluor 549</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648i">FAB3648I</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648i" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648JF585" data-titleoverwrite="Janelia Fluor 585"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf585">Janelia Fluor 585</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf585">FAB3648JF585</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf585" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648JF635" data-titleoverwrite="Janelia Fluor 635"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf635">Janelia Fluor 635</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf635">FAB3648JF635</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf635" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648J" data-titleoverwrite="Janelia Fluor 646"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648j">Janelia Fluor 646</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648j">FAB3648J</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648j" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648JF669" data-titleoverwrite="Janelia Fluor 669"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf669">Janelia Fluor 669</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf669">FAB3648JF669</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648jf669" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648MFV450" data-titleoverwrite="mFluor Violet 450 SE"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv450">mFluor Violet 450 SE</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv450">FAB3648MFV450</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv450" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648MFV500" data-titleoverwrite="mFluor Violet 500 SE"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv500">mFluor Violet 500 SE</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv500">FAB3648MFV500</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv500" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648MFV610" data-titleoverwrite="mFluor Violet 610 SE"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv610">mFluor Violet 610 SE</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv610">FAB3648MFV610</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648mfv610" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648PEATT594" data-titleoverwrite="PE/Atto594"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648peatt594">PE/Atto594</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648peatt594">FAB3648PEATT594</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648peatt594" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> <div class="commerce-atc-conjugates-formulations-productline mt-2 border-top" data-catalog="FAB3648PECY55" data-titleoverwrite="PE/Cy5.5"> <div class="row my-2 mx-0"> <div class="col-8 my-auto"> <div class="row"> <div class="commerce-atc-catnum col-12 col-md-6 p-0 font-weight-bold"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648pecy55">PE/Cy5.5</a> </div> <div class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648pecy55">FAB3648PECY55</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/complement-component-c5ar1-antibody-347214_fab3648pecy55" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> 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class="commerce-atc-price col-12 col-md-6 p-0"> <a href="/p/antibodies/human-complement-component-c5ar1-pe-conjugated-antibody-347214_fab3648p">FAB3648P</a> </div> </div> </div> <div class="commerce-atc-atc-btn col-4 p-0"> <a type="button" href="/p/antibodies/human-complement-component-c5ar1-pe-conjugated-antibody-347214_fab3648p" class="btn button--primary col-xs-4 order-last btn-md-block w-100 p-1"> View Product </a> </div> </div> </div> </div> </div> </div> </div> </div> <div id="guarantee-statement" class="text-right" data-section="section-base--guarantee-statement"> <span class="icon-icon-check-circle"></span> <a href="/guarantee">100% Guarantee</a> </div> </div> </div> </div> </div> <div id="tabs-distributor" class="row"> <div class="tab-content col-xl-9 mt-2"> <div data-section="section-base--nav-tabs-content"> <ul class="nav nav-tabs nav-fill" id="productTab" role="tablist"> <li class="nav-item" role="presentation"> <a class="nav-link tab-anchor active" 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<h4>Applications</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> <h4 class="d-block">Validated:</h4> <div class="d-block pb-2"> CyTOF-ready, Flow Cytometry, Neutralization </div> <h4 class="d-block">Cited:</h4> <div class="d-block pb-2"> Flow Cytometry, Immunohistochemistry-Paraffin </div> </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Label</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Unconjugated </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Antibody Source</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Monoclonal Mouse IgG<sub>2A</sub> Clone # 347214 </div> </div> </div> <div class="container"> <div class="row product-data"> <div class="col-lg-6 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4><a href="/t/complement-component-c5ar1/antibodies">View all Complement Component C5aR1 Antibodies »</a></h4> </div> </div> </div> </div> <div class="border-top border-bottom recommended-products-section" id="recommendation-viewed" data-product_code="MAB3648" data-type=viewed></div> <div id="product-specifications" class="bt-pp-border-bottom py-5" data-section="section-base--product-specifications"> <h3>Product Specifications</h3> <div class="mt-4 py-2 container"> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Immunogen</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> NS0 mouse myeloma cell line transfected with human Complement Component C5a R1<br />Met1-Val350<br />Accession # P21730 </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Specificity</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Detects human Complement Component C5a R1. Stains human Complement Component C5a R1 transfected cells but not irrelevant transfectants. </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Clonality</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Monoclonal </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Host</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Mouse </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Isotype</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> IgG<sub>2A</sub> </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Endotoxin Level</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> <0.10 EU per 1 μg of the antibody by the LAL method. </div> </div> </div> </div> <div id="scientific-data" class="bt-pp-border-bottom py-5" data-anchor-label="Scientific Data" data-section="section-base--scientific-data"> <div> <h3>Scientific Data Images for Human Complement Component C5aR1 Antibody </h3> </div> <div class="product-data-wrapper mt-5" id="scientific-data-table" data-scientific-count="-2"> <div> <div class="row m___product-data-examples my-4" data-section="product-image-divs"> <div class="col-md-2 border-0 mb-3"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand="rnd"> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.bio-techne.com/images/products/antibody/Complement_Component_C5a_R1_MAB3648_Block_Neutralize_9166.jpg" data-srcset="https://resources.bio-techne.com/images/products/antibody/Complement_Component_C5a_R1_MAB3648_Block_Neutralize_9166.jpg" alt="N-Acetyl-beta -D-Glucosa-minidase Release Induced by Complement Component C5a and Neutralization by Human Complement Component C5a R1 Antibody." title="N-Acetyl-beta -D-Glucosa-minidase Release Induced by Complement Component C5a and Neutralization by Human Complement Component C5a R1 Antibody." data-caption="Recombinant Human Complement Component C5a (Catalog # <a href="/p/proteins-enzymes/recombinant-human-complement-component-c5a-protein_2037-c5" target="_self">2037-C5</a>) induces N-acetyl-beta -D-glucosa-minidase release in the dibutyryl cyclic-AMP differentiated U937 human histiocytic lymphoma cell line in a dose-dependent manner (orange line). N-Acetyl-beta -D-Glucosaminidase Release elicited by Recombinant Human Complement Component C5a (10 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Complement Component C5a R1 Monoclonal Antibody (Catalog # MAB3648). The ND<sub>50</sub> is typically 2-10 µg/mL in the presence of cytochalasin-B." data-badges="" data-application="Neutralization" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </div> <div class="col-md-9 border-0 align-top"> <h4 class="font-weight-bold">N-Acetyl-beta -D-Glucosa-minidase Release Induced by Complement Component C5a and Neutralization by Human Complement Component C5a R1 Antibody.</h4> Recombinant Human Complement Component C5a (Catalog # <a href="/p/proteins-enzymes/recombinant-human-complement-component-c5a-protein_2037-c5" target="_self">2037-C5</a>) induces N-acetyl-beta -D-glucosa-minidase release in the dibutyryl cyclic-AMP differentiated U937 human histiocytic lymphoma cell line in a dose-dependent manner (orange line). N-Acetyl-beta -D-Glucosaminidase Release elicited by Recombinant Human Complement Component C5a (10 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Complement Component C5a R1 Monoclonal Antibody (Catalog # MAB3648). The ND<sub>50</sub> is typically 2-10 µg/mL in the presence of cytochalasin-B. </div> </div> </div> <span class="product-data-wrapper table" id="more-scientific-data" style="display:none"> </span> </div> </div> <div id="applications" class="py-5 bt-pp-border-bottom" data-anchor-label="Applications" data-section="section-antibody--applications"> <h3>Applications for Human Complement Component C5aR1 Antibody </h3> <div class="mt-5 py-2 container"> <div class="row"> <div class="col-lg-3 border font-weight-bold text-bg-dark py-2 align-top text-md-left text-white bg-dark-bt-blue d-none d-lg-block"> Application </div> <div class="col-lg-9 border align-top py-2 font-weight-bold text-white bg-dark-bt-blue d-none d-lg-block"> Recommended Usage </div> </div> <div class="row"> <div class="col-lg-3 border font-weight-bold product-data-label py-2 align-top text-md-left text-break"> <h4>CyTOF-ready</h4> </div> <div class="col-lg-9 border align-top py-2"> Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation. </div> </div> <div class="row"> <div class="col-lg-3 border font-weight-bold product-data-label py-2 align-top text-md-left text-break"> <h4>Flow Cytometry</h4> </div> <div class="col-lg-9 border align-top py-2"> 2.5 µg/10<sup>6</sup> cells <br/>Sample: Human peripheral blood granulocytes<br> </div> </div> <div class="row"> </div> <div class="row"> <div class="col-lg-3 border font-weight-bold product-data-label py-2 align-top text-md-left text-break"> <h4>Neutralization</h4> </div> <div class="col-lg-9 border align-top py-2"> Measured by its ability to neutralize Complement Component C5a-induced N-acetyl-beta -D-glucosaminidase release in the dibutyryl cyclic-AMP differentiated U937 human histiocytic lymphoma cell line. Gerard, NP and Gerard, C. (1990) Biochemistry <b>29:</b>9274. The Neutralization Dose (ND<sub>50</sub>) is typically 2-10 µg/mL in the presence of 10 ng/mL Recombinant Human Complement Component C5a and cytochalasin‑B. </div> </div> </div> <div class="product-data-wrapper mt-5"> Please Note: Optimal dilutions of this antibody should be experimentally determined. </div> </div> <div id="preparation--storage" class="bt-pp-border-bottom py-5" data-section="section-base--preparation-storage"> <h3>Formulation, Preparation, and Storage</h3> <div class="mt-4 py-2 container"> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Purification</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Protein A or G purified from hybridoma culture supernatant </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Reconstitution</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> <div class="atc-container"> <div class="commerce-atc-reconstitution atc-block" data-type="reconstitution" data-blockid="ReconstitutionCart"> <div class="commerce-atc-reconstitution__instructions"> Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration. </div> <p class="atc-modal"></p> <form action="/commerce/addtocart" method="post" class="add-to-cart-block" data-productcode=""> <div class="commerce-atc-reconstitution-header atc-header col-four row border-top pt-2 m-0"> <div class="commerce-atc-catnum atc-head col-md-6 font-weight-bold p-0">Reconstitution Buffer Available:</div> <div class="commerce-atc-price atc-head col-md-3 font-weight-bold">Size / Price</div> <div class="commerce-atc-quantity atc-head col-md-3 text-right font-weight-bold p-0">Qty</div> </div> <div class="spinner-border spinner-border-sm mt-3 ml-3" role="status"> <span class="sr-only">Loading...</span> </div> <div class="d-none search-product-mask"> <div id="ReconstitutionCart" class="atc-lines"> <div class="commerce-atc-reconstitution-line productline col-four row py-2 m-0" data-catalog="RB01"> <div class="commerce-atc-title col-md-6 p-0"> <a href="">RB01: </a> </div> <div class="commerce-atc-price col-md-3"> </div> <div class="commerce-atc-quantity col-md-3 text-right p-0"> </div> </div> </div> <div class="atc-control ReconstitutionCart-control text-right mt-2"> <input type="submit" value="Add To Cart" class="atc-add-button btn a___button-atc col-xs-4"/> </div> </div> </form> </div> </div> </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Formulation</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Shipping</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below. </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Stability & Storage</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> <b>Use a manual defrost freezer and avoid repeated freeze-thaw cycles. </b><UL><LI>12 months from date of receipt, -20 to -70 °C as supplied.</LI><LI>1 month, 2 to 8 °C under sterile conditions after reconstitution.</LI><LI>6 months, -20 to -70 °C under sterile conditions after reconstitution.</LI></UL> </div> </div> </div> </div> <div id="background" class="py-5 bt-pp-border-bottom" data-section="section-base--background-info"> <h3>Background: Complement Component C5aR1</h3> <article class="product-data-wrapper"> <P>Complement Component C5a R1 (C5aR1), also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5aR binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of proinflammatory mediators. In contrast, C5aR1/C5a interactions are protective during allergen sensitization. Human C5aR1 shares 66% amino acid sequence identity with mouse and rat C5aR.</P> </article> <div id="background_wrapper" class="px-3 mt-2"> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Long Name</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> Complement Component C5a Receptor 1 </div> </div> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Alternate Names</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> C5AR1, CD88, Complement Component C5a R1 </div> </div> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Entrez Gene IDs</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> <a href="https://www.ncbi.nlm.nih.gov/gene?term=728" class="a___link-external" target="_blank" rel="nofollow">728</a> (Human); <a href="https://www.ncbi.nlm.nih.gov/gene?term=12273" class="a___link-external" target="_blank" rel="nofollow">12273</a> (Mouse) </div> </div> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Gene Symbol</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> C5AR1 </div> </div> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>UniProt</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> <a href="https://www.uniprot.org/uniprot/?query=P21730" class="a___link-external" target="_blank" rel="nofollow">P21730</a> </div> </div> </div> <h4 class="mt-3">Additional Complement Component C5aR1 Products</h4> <ul class="list-unstyled"> <li><a href="/t/complement-component-c5ar1" data-product="Complement Component C5aR1">All Products for Complement Component C5aR1 </a></li> <li><a href="/t/complement-component-c5ar1/cdna-clones" data-application="Complement Component C5aR1 cDNA Clones">Complement Component C5aR1 cDNA Clones </a></li> <li><a href="/t/complement-component-c5ar1/lysates" data-application="Complement Component C5aR1 Lysates">Complement Component C5aR1 Lysates </a></li> <li><a href="/t/complement-component-c5ar1/antibodies" data-application="Complement Component C5aR1 Primary Antibodies">Complement Component C5aR1 Primary Antibodies </a></li> <li><a href="/t/complement-component-c5ar1/proteins-enzymes" data-application="Complement Component C5aR1 Proteins and Enzymes">Complement Component C5aR1 Proteins and Enzymes </a></li> </ul> </div> <div id="product-documents" data-section="section-base--product-documents"> <div id="accordion" class="border mb-4"> <div class="rounded-top bg-white"> <h3 class="m-0 p-3"> Product Documents for Human Complement Component C5aR1 Antibody </h3> </div> <div class="vtab-section" data-section="Product Datasheets"> <div class="card-header rounded-top"> <a class="" data-toggle="collapse" data-target="#collapse_two" aria-expanded="true" aria-controls="collapse_two" id="product-datasheets-link"> <h5 class="mb-0"> Product Datasheets </h5> </a> </div> <div id="collapse_two" class="collapse show prod_datasheet_link" aria-labelledby="heading_two" data-parent="#accordion"> <div class="card-body"> <div class="row"> <div class="col-md-6"> <a href="https://resources.rndsystems.com/pdfs/datasheets/mab3648.pdf" class="datasheet_link" target="_blank" rel="nofollow">Download Product Datasheets</a> </div> </div> </div> </div> </div> <div class="card-header"> <a data-toggle="collapse" data-target="#collapse_one" aria-expanded="false" class="collapsed" aria-controls="collapse_one"> <h5 class="mb-0"> COA </h5> </a> </div> <div id="collapse_one" class="collapse " aria-labelledby="heading_one" data-parent="#accordion"> <div class="card-body"> <form novalidate="novalidate" data-drupal-selector="product-coa-form" action="#coa-form" method="post" id="product-coa-form" accept-charset="UTF-8"> <div class="row"> <div class="col-12"> <h2>Certificate of Analysis</h2> <p>To download a Certificate of Analysis, please enter a lot number in the search box below.</p> <p><strong>Note:</strong> Certificate of Analysis not available for kit components.</p> </div> </div> <section class="row"> <div class="col-md-6"> <form novalidate="novalidate" data-drupal-selector="product-coa-form"> <div class="form-row align-items-center"> <div class="col-md-10 my-1"> <input data-drupal-selector="form-brg5pdbeqtuwy2acbdm6igfogjqb-coekjfzluqb0" type="hidden" name="form_build_id" value="form-_BRG5pDbEQtUwY2ACbdm6IGfOGjQB_-CoEKJfzLUqB0" /> <input data-drupal-selector="edit-product-coa-form" type="hidden" name="form_id" value="product_coa_form" /> <input data-drupal-selector="edit-product-code" type="hidden" name="product_code" value="MAB3648" /> <div class="js-form-item form-item pb-3 js-form-type-textfield 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class="mb-0"> SDS </h5> </a> </div> <div id="collapse_three" class="collapse rounded-bottom" aria-labelledby="heading_three" data-parent="#accordion"> <div class="card-body"> <div class="row sds-row"> <div class="select_wrapper col"> <select class="sds_country_select dropdown-chevron form-control mb-2" data-uri="https://aero.bio-techne.com/sds/pdf/mab3648"> <option value="">Select SDS Language</option> <option value="cs-cz">Czech</option> <option value="da-dk">Danish</option> <option value="nl-nl">Dutch</option> <option value="en-us">English</option> <option value="de-de">German</option> <option value="fr-fr">French</option> <option value="hu-hu">Hungarian</option> <option value="it-it">Italian</option> <option value="nb-no">Norwegian</option> <option value="pl-pl">Polish</option> <option value="es-es">Spanish</option> <option value="sv-se">Swedish</option> </select> <span class="sds-pdf-result datasheet-loading"></span> </div> <div class="col my-3 pt-1 text-center text-lg-left"> <a 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