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Search results for: Enamel renal syndrome

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1081</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Enamel renal syndrome</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1081</span> Enamel Structure Defect, the Rare Dental Anomaly: Isolated or Syndromic</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nehal%20F.%20Hassib">Nehal F. Hassib</a>, <a href="https://publications.waset.org/abstracts/search?q=Rasha%20M.%20El%20Hossini"> Rasha M. El Hossini</a>, <a href="https://publications.waset.org/abstracts/search?q=Inas%20M.%20Sayed"> Inas M. Sayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Maha%20R.%20Abouzeid"> Maha R. Abouzeid</a>, <a href="https://publications.waset.org/abstracts/search?q=Nermeen%20A.%20Bayoumi"> Nermeen A. Bayoumi</a>, <a href="https://publications.waset.org/abstracts/search?q=Aida%20M.%20Mosaad"> Aida M. Mosaad</a>, <a href="https://publications.waset.org/abstracts/search?q=Lamia%20K.%20Gadallah"> Lamia K. Gadallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Moataz%20Bellah%20A.%20T.%20%20Abdelbari"> Moataz Bellah A. T. Abdelbari</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20A.%20El-Sayed"> Heba A. El-Sayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Hasnaa%20Elbendary"> Hasnaa Elbendary</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghada%20Abdel-Salam"> Ghada Abdel-Salam</a>, <a href="https://publications.waset.org/abstracts/search?q=Maha%20Zaki"> Maha Zaki</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20I.%20Mostafa"> Mostafa I. Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20S.%20Abdel-Hamid"> Mohamed S. Abdel-Hamid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Enamel, the outermost layer of the tooth crown, is the hardest dental tissue and serves as a protective barrier. Amelogenesis, the process of enamel formation, is regulated by multiple genes to ensure normal, defect-free enamel. Defective enamel manifests as hypoplasia or as amelogenesis imperfecta (AI), which may occur in isolation or as part of a syndrome. This study presents 29 patients from 18 unrelated families (16 females and 13 males) who exhibited distinctive enamel abnormalities. We conducted thorough clinical examinations and requested laboratory and radiological investigations. Blood samples were collected for molecular analysis, utilizing a targeted panel for known AI variants and whole exome sequencing for unknown variants. Eleven variants linked to enamel anomalies were identified: four genes associated with isolated AI (WDR72, ACP4, SLC24A4, and FAM83H) and seven associated with syndromic forms, including enamel renal syndrome (FAM20A), tricho-dento-osseous syndrome (DLX3), Jalili syndrome (CNNM4), and others linked to neurological and mitochondrial disorders, skeletal dysplasia, and peroxisome disorders. Abnormal oral and dental phenotypes in individuals may indicate serious inherited disorders. Enamel defects have significant implications for aesthetics, function, and patients' psychological well-being. Dental examination, alongside clinical and molecular investigations, is crucial for the accurate diagnosis and prediction of inherited conditions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=amelogenesis%20imperfecta" title="amelogenesis imperfecta">amelogenesis imperfecta</a>, <a href="https://publications.waset.org/abstracts/search?q=enamel%20defect" title=" enamel defect"> enamel defect</a>, <a href="https://publications.waset.org/abstracts/search?q=Enamel%20renal%20syndrome" title=" Enamel renal syndrome"> Enamel renal syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=DLX3" title=" DLX3"> DLX3</a>, <a href="https://publications.waset.org/abstracts/search?q=Jalili%20syndrome" title=" Jalili syndrome"> Jalili syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=WDR72" title=" WDR72"> WDR72</a>, <a href="https://publications.waset.org/abstracts/search?q=FAM83H" title=" FAM83H"> FAM83H</a>, <a href="https://publications.waset.org/abstracts/search?q=whole%20exome%20sequencing" title=" whole exome sequencing"> whole exome sequencing</a> </p> <a href="https://publications.waset.org/abstracts/191884/enamel-structure-defect-the-rare-dental-anomaly-isolated-or-syndromic" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/191884.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">24</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1080</span> Clinical Profile of Renal Diseases in Children in Tertiary Care Centre</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jyoti%20Agrawal">Jyoti Agrawal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Renal diseases in children and young adult can be difficult to diagnose early as it may present only with few symptoms, tends to have different course than adult and respond variously to different treatment. The pattern of renal disease in children is different from developing countries as compared to developed countries. Methods: This study was a hospital based prospective observational study carried from March, 2014 to February 2015 at BP Koirala institute of health sciences. Patients with renal disease, both inpatient and outpatient from birth to 14 years of age were enrolled in the study. The diagnosis of renal disease was be made on clinical and laboratory criteria. Results: Total of 120 patients were enrolled in our study which contributed to 3.74% % of total admission. The commonest feature of presentation was edema (75%), followed by fever (65%), hypertension (60%), decreased urine output (45%) and hematuria (25%). Most common diagnosis was acute glomerulonephritis (40%) followed by Nephrotic syndrome (25%) and urinary tract infection (25%). Renal biopsy was done for 10% of cases and most of them were steroid dependent nephrotic syndrome. 5% of our cases expired because of multiorgan dysfunction syndrome, sepsis and acute kidney injury. Conclusion: Renal disease contributes to a large part of hospital pediatric admission as well as mortality and morbidity to the children. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glomerulonephritis" title="glomerulonephritis">glomerulonephritis</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrotic%20syndrome" title=" nephrotic syndrome"> nephrotic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20disease" title=" renal disease"> renal disease</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infection" title=" urinary tract infection"> urinary tract infection</a> </p> <a href="https://publications.waset.org/abstracts/79003/clinical-profile-of-renal-diseases-in-children-in-tertiary-care-centre" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79003.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">426</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1079</span> SEM Analysis of the Effectiveness of the Acid Etching on Cat Enamel</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=C.%20Gallottini">C. Gallottini</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20Di%20Mari"> W. Di Mari</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20De%20Carolis"> C. De Carolis</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Dolci"> A. Dolci</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Dolci"> G. Dolci</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Gallottini"> L. Gallottini</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Barraco"> G. Barraco</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Eramo"> S. Eramo </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this paper is to summarize the literature on micromorphology and composition of the enamel of the cat and present an original experiment by SEM on how it responds to the etching with ortophosphoric acid for the time recommended in the veterinary literature (30", 45", 60"), derived from research and experience on human enamel; 21 teeth of cat were randomly divided into three groups of 7 (A, B, C): Group A was subjected to etching for 30 seconds by means of orthophosphoric acid to 40% on a circular area with diameter of about 2mm of the enamel coronal; the Groups B and C had the same treatment but, respectively, for 45 and 60 seconds. The samples obtained were observed by SEM to constant magnification of 1000x framing, in particular, the border area between enamel exposed and not exposed to etching to highlight differences. The images were subjected to the analysis of three blinded experienced operators in electron microscopy. In the enamel of the cat the etching for the times considered is not optimally effective for the purpose adhesives and the presence of a thick prismless layer could explain this situation. To improve this condition may clinically in the likeness of what is proposed for the enamel of human deciduous teeth: a bevel or a chamfer of 1 mm on the contour of the cavity to discover the prismatic enamel and increase the bonding surface. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cat%20enamel" title="cat enamel">cat enamel</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a>, <a href="https://publications.waset.org/abstracts/search?q=veterinary%20dentistry" title=" veterinary dentistry"> veterinary dentistry</a>, <a href="https://publications.waset.org/abstracts/search?q=acid%20etching" title=" acid etching"> acid etching</a> </p> <a href="https://publications.waset.org/abstracts/1802/sem-analysis-of-the-effectiveness-of-the-acid-etching-on-cat-enamel" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1802.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">307</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1078</span> Simulation Of A Renal Phantom Using the MAG 3</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ati%20Moncef">Ati Moncef</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We describe in this paper the results of a phantom of dynamics renal with MAG3. Our phantom consisted of (tow shaped of kidneys, 1 liver). These phantoms were scanned with static and dynamic protocols and compared with clinical data. in a normal conditions we use our phantoms it's possible to acquire a renal images when we can be compared with clinical scintigraphy. In conclusion, Renal phantom also can use in the quality control of a renal scintigraphy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Renal%20scintigraphy" title="Renal scintigraphy">Renal scintigraphy</a>, <a href="https://publications.waset.org/abstracts/search?q=MAG3" title=" MAG3"> MAG3</a>, <a href="https://publications.waset.org/abstracts/search?q=Nuclear%20medicine" title=" Nuclear medicine"> Nuclear medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=Gamma%20Camera." title=" Gamma Camera."> Gamma Camera.</a> </p> <a href="https://publications.waset.org/abstracts/21031/simulation-of-a-renal-phantom-using-the-mag-3" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21031.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">401</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1077</span> Spontaneous Tumour Lysis in Acute Myeloid Leukemia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rojith%20K.%20Balakrishnan">Rojith K. Balakrishnan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Spontaneous tumour lysis syndrome is a constellation of electrolyte abnormalities and an acute renal failure which occurs in the setting of rapid cell turnover prior to the administration of cytotoxic chemotherapy. While spontaneous tumour lysis well-described in patients with Burkitt lymphoma, it is thought to occur less commonly in patients with other hematological malignancies. We present a case of forty-year-old female who presented with features of acute renal failure, on further evaluation turned out to be a newly diagnosed acute myeloid leukemia with spontaneous tumour lysis best of our knowledge only three cases of AML with spontaneous tumour lysis has reported world wide. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AML" title="AML">AML</a>, <a href="https://publications.waset.org/abstracts/search?q=tumour%20lysis" title=" tumour lysis"> tumour lysis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20failure" title=" renal failure"> renal failure</a>, <a href="https://publications.waset.org/abstracts/search?q=myeloid%20leukemia" title=" myeloid leukemia"> myeloid leukemia</a> </p> <a href="https://publications.waset.org/abstracts/28705/spontaneous-tumour-lysis-in-acute-myeloid-leukemia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28705.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">294</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1076</span> Outcomes of Live Renal Donors with a History of Nephrolithiasis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bin%20Mohamed%20Ebrahim">Bin Mohamed Ebrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Aminesh%20Singla"> Aminesh Singla</a>, <a href="https://publications.waset.org/abstracts/search?q=Henry%20Pleass"> Henry Pleass</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aim: There is an ongoing gap in renal transplantation between organs available for donation and recipients on the waiting list. Live donors with pre-existing or a history of renal calculi were thought to be a relative contraindication due to safety concerns for donors. We aim to review current literature assessing outcomes of donors who were found to have a history of renal calculi. Methods: Ovid and Embase were searched between 1960 to 2021 using key terms and Medical Subject Headings (MeSH) – nephrolithiasis, renal stones, renal transplantation and renal graft. Articles included conference proceedings and journal articles and were not excluded based on patient numbers. Studies were excluded if the specific organ was not identified, duplicated reports found or if post-transplant outcomes were not recorded. Outcomes were donor’s renal function or renal calculi recurrence postoperatively. Results: Upon reviewing 344 articles, 14 manuscripts met inclusion criteria. A total of 152 live donors were identified as having pre-existing or with a history of renal calculi at pre-operative workup. The mean stone size was 2.6 4mm (1 – 16) with a mean follow-up duration of 31.8 months (1 – 96). Seven studies had both outcomes. None showed renal complications or stone recurrence. The remaining studies contained 2 out of 84 patients having recurrent nephrolithiasis. Conclusion: Data suggests minimal morbidity involved for live renal donors with a history of nephrolithiasis. This should encourage surgeons to continue recruiting such donors for kidney transplantation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20transplantation" title="renal transplantation">renal transplantation</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20graft" title=" renal graft"> renal graft</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrolithiasis" title=" nephrolithiasis"> nephrolithiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20calculi" title=" renal calculi"> renal calculi</a>, <a href="https://publications.waset.org/abstracts/search?q=live%20donor" title=" live donor"> live donor</a> </p> <a href="https://publications.waset.org/abstracts/140954/outcomes-of-live-renal-donors-with-a-history-of-nephrolithiasis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140954.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1075</span> Anomalous Course of Left Ovarian Vein Associated with Pelvic Congestion Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Viyango%20Pandian">Viyango Pandian</a>, <a href="https://publications.waset.org/abstracts/search?q=Kumaresh%20Athiyappan"> Kumaresh Athiyappan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pelvic congestion Syndrome (PCS) is usually seen in multiparous women who give history of chronic dull-aching pelvic pain. We report a case of a 17 year old unmarried female, who presented with acute onset of chronic dull-aching abdominal pain in the left iliac fossa, which particularly increased during menstruation and was finally diagnosed to be pelvic congestion syndrome. On ultrasonography, multiple tortuous and dilated veins were observed in the left adnexa. Both ovaries appeared normal in size, volume and echotexture. Computed tomography (CT) angiography was performed to precisely delineate the venous pathway and to assess any associated abnormality; which showed a dilated and tortuous left ovarian vein with an anomalous course around the left kidney and draining into the left renal vein. Clinical parameters and hormonal levels were within normal limits. This is a rare case of anomalous course of left ovarian vein associated with pelvic congestion syndrome. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anomalous%20course%20of%20ovarian%20vein" title="anomalous course of ovarian vein">anomalous course of ovarian vein</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=pelvic%20congestion%20syndrome" title=" pelvic congestion syndrome"> pelvic congestion syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrasonography" title=" ultrasonography"> ultrasonography</a> </p> <a href="https://publications.waset.org/abstracts/70992/anomalous-course-of-left-ovarian-vein-associated-with-pelvic-congestion-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70992.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">418</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1074</span> Effect of Tooth Bleaching Agents on Enamel Demineralisation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Najlaa%20Yousef%20Qusti">Najlaa Yousef Qusti</a>, <a href="https://publications.waset.org/abstracts/search?q=Steven%20J.%20Brookes"> Steven J. Brookes</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20A.%20Brunton"> Paul A. Brunton</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Tooth discoloration can be an aesthetic problem, and tooth whitening using carbamide peroxide bleaching agents are a popular treatment option. However, there are concerns about possible adverse effects such as demineralisation of the bleached enamel; however, the cause of this demineralisation is unclear. Introduction: Teeth can become stained or discoloured over time. Tooth whitening is an aesthetic solution for tooth discoloration. Bleaching solutions of 10% carbamide peroxide (CP) have become the standard agent used in dentist-prescribed and home-applied ’vital bleaching techniques’. These materials release hydrogen peroxide (H₂O₂), the active whitening agent. However, there is controversy in the literature regarding the effect of bleaching agents on enamel integrity and enamel mineral content. The purpose of this study was to establish if carbamide peroxide bleaching agents affect the acid solubility of enamel (i.e., make teeth more prone to demineralisation). Materials and Methods: Twelve human premolar teeth were sectioned longitudinally along the midline and varnished to leave the natural enamel surface exposed. The baseline behavior of each tooth half in relation to its demineralisation in acid was established by sequential exposure to 4 vials containing 1ml of 10mM acetic acid (1 minute/vial). This was followed by exposure to 10% CP for 8 hours. After washing in distilled water, the tooth half was sequentially exposed to 4 further vials containing acid to test if the acid susceptibility of the enamel had been affected. The corresponding tooth half acted as a control and was exposed to distilled water instead of CP. The mineral loss was determined by measuring [Ca²⁺] and [PO₄³⁻] released in each vial using a calcium ion-selective electrode and the phosphomolybdenum blue method, respectively. The effect of bleaching on the tooth surfaces was also examined using SEM. Results: Exposure to carbamide peroxide did not significantly alter the susceptibility of enamel to acid attack, and SEM of the enamel surface revealed a slight alteration in surface appearance. SEM images of the control enamel surface showed a flat enamel surface with some shallow pits, whereas the bleached enamel appeared with an increase in surface porosity and some areas of mild erosion. Conclusions: Exposure to H₂O₂ equivalent to 10% CP does not significantly increase subsequent acid susceptibility of enamel as determined by Ca²⁺ release from the enamel surface. The effects of bleaching on mineral loss were indistinguishable from distilled water in the experimental system used. However, some surface differences were observed by SEM. The phosphomolybdenum blue method for phosphate is compromised by peroxide bleaching agents due to their oxidising properties. However, the Ca²⁺ electrode is unaffected by oxidising agents and can be used to determine the mineral loss in the presence of peroxides. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bleaching" title="bleaching">bleaching</a>, <a href="https://publications.waset.org/abstracts/search?q=carbamide%20peroxide" title=" carbamide peroxide"> carbamide peroxide</a>, <a href="https://publications.waset.org/abstracts/search?q=demineralisation" title=" demineralisation"> demineralisation</a>, <a href="https://publications.waset.org/abstracts/search?q=teeth%20whitening" title=" teeth whitening"> teeth whitening</a> </p> <a href="https://publications.waset.org/abstracts/132807/effect-of-tooth-bleaching-agents-on-enamel-demineralisation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/132807.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">126</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1073</span> Renal Amyloidosis in Domestic Iranian Sheep</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Keivan%20Jamshidi">Keivan Jamshidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Fateme%20Behbahani"> Fateme Behbahani</a>, <a href="https://publications.waset.org/abstracts/search?q=Sara%20Omidi"> Sara Omidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadia%20Shahi"> Nadia Shahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alireza%20Farkhonde"> Alireza Farkhonde</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Amyloidosis represents a heterogenous group of diseases that have in common the deposition of fibrils composed of proteins of beta-pleated sheet structure, which can be specifically identified by histochemistry using the Congo red or similar stains. Between October 2013 to April 2014 (6 months) different patterns of renal amyloidosis was diagnosed on histopathological examination of kidneys belong to 196 out of 7065 slaughtered sheep subjected to postmortem examination. Microscopic examination of renal tissue sections stained with H&E and CR staining techniques revealed 3 patterns of renal amyloid deposition; including glomerular (22.72%), medullary (68.18%), and vascular (9.09%) were recognized. Renal medullary amyloidosis (RMA) was detected as the most prevalence pattern of renal amyloidosis in domestic sheep. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sheep" title="sheep">sheep</a>, <a href="https://publications.waset.org/abstracts/search?q=amyloidosis" title=" amyloidosis"> amyloidosis</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=slaughterhouse" title=" slaughterhouse"> slaughterhouse</a> </p> <a href="https://publications.waset.org/abstracts/79052/renal-amyloidosis-in-domestic-iranian-sheep" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79052.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">375</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1072</span> Pattern of Biopsy Proven Renal Disease and Association between the Clinical Findings with Renal Pathology in Eastern Nepal</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manish%20Subedi">Manish Subedi</a>, <a href="https://publications.waset.org/abstracts/search?q=Bijay%20Bartaula"> Bijay Bartaula</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashok%20R.%20Pant"> Ashok R. Pant</a>, <a href="https://publications.waset.org/abstracts/search?q=Purbesh%20Adhikari"> Purbesh Adhikari</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjib%20K.%20Sharma"> Sanjib K. Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The pattern of glomerular disease varies worldwide. In absence of kidney disease/Kidney biopsy registry in Nepal, the exact etiology of different forms of glomerular disease is primarily unknown in our country. Method: We retrospectively analyzed 175 cases of renal biopsies performed from dated September 2014 to August 2016 at B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Results: The commonest indication for renal biopsy was nephrotic syndrome (34.9%), followed by Systemic lupus erythematosus with suspected renal involvement (22.3%). Majority of patients were in the 30-60 year bracket (57.2%), with the mean age of the patients being 35.37 years. The average number of glomeruli per core was 13, with inadequate sampling in 5.1%. IgA nephropathy (17%) was found to be the most common primary glomerular disease, followed by membranous nephropathy (14.6%) and FSGS (14.6%). The commonest secondary glomerular disease was lupus nephritis. Complications associated with renal biopsy were pain at biopsy site in 18% of cases, hematuria in 6% and perinephric hematoma in 4% cases. Conclusion: The commonest primary and secondary glomerular disease was IgA nephropathy and lupus nephritis respectively. The high prevalence of Systemic lupus erythematosus with lupus nephritis among Nepalese in comparison with other developing countries warrants further evaluation. As an initial attempt towards documentation of glomerular diseases in the national context, this study should serve as a stepping stone towards the eventual establishment of a full-fledged national registry of glomerular diseases in Nepal. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glomerular" title="glomerular">glomerular</a>, <a href="https://publications.waset.org/abstracts/search?q=Nepal" title=" Nepal"> Nepal</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20biopsy" title=" renal biopsy"> renal biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=systemic%20lupus%20erythematoses" title=" systemic lupus erythematoses"> systemic lupus erythematoses</a> </p> <a href="https://publications.waset.org/abstracts/80240/pattern-of-biopsy-proven-renal-disease-and-association-between-the-clinical-findings-with-renal-pathology-in-eastern-nepal" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80240.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">229</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1071</span> Raman, Atomic Force Microscopy and Mass Spectrometry for Isotopic Ratios Methods Used to Investigate Human Dentine and Enamel</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nicoleta%20Simona%20Vedeanu">Nicoleta Simona Vedeanu</a>, <a href="https://publications.waset.org/abstracts/search?q=Rares%20Stiufiuc"> Rares Stiufiuc</a>, <a href="https://publications.waset.org/abstracts/search?q=Dana%20Alina%20Magdas"> Dana Alina Magdas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A detailed knowledge of the teeth structure is mandatory to understand and explain the defects and the dental pathology, but especially to take a correct decision regarding dental prophylaxis and treatment. The present work is an alternative study to the traditional investigation methods used in dentistry, a study based on the use of modern, sensitive physical methods to investigate human enamel and dentin. For the present study, several teeth collected from patients of different ages were used for structural and dietary investigation. The samples were investigated by Raman spectroscopy for the molecular structure analysis of dentin and enamel, atomic force microscopy (AFM) to view the dental topography at the micrometric size and mass spectrometry for isotopic ratios as a fingerprint of patients’ personal diet. The obtained Raman spectra and their interpretation are in good correlation with the literature and may give medical information by comparing affected dental structures with healthy ones. AFM technique gave us the possibility to study in details the dentin and enamel surface to collect information about dental hardness or dental structural changes. δ¹³C values obtained for the studied samples can be classified in C4 category specific to young people and children diet (sweets, cereals, juices, pastry). The methods used in this attempt furnished important information about dentin and enamel structure and dietary habits and each of the three proposed methods can be extended at a larger level in the study of the teeth structure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AFM" title="AFM">AFM</a>, <a href="https://publications.waset.org/abstracts/search?q=dentine" title=" dentine"> dentine</a>, <a href="https://publications.waset.org/abstracts/search?q=enamel" title=" enamel"> enamel</a>, <a href="https://publications.waset.org/abstracts/search?q=Raman%20spectroscopy" title=" Raman spectroscopy"> Raman spectroscopy</a> </p> <a href="https://publications.waset.org/abstracts/96040/raman-atomic-force-microscopy-and-mass-spectrometry-for-isotopic-ratios-methods-used-to-investigate-human-dentine-and-enamel" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96040.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">145</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1070</span> Development of a Spatial Data for Renal Registry in Nigeria Health Sector</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Adekunle%20Kolawole%20Ojo">Adekunle Kolawole Ojo</a>, <a href="https://publications.waset.org/abstracts/search?q=Idowu%20Peter%20Adebayo"> Idowu Peter Adebayo</a>, <a href="https://publications.waset.org/abstracts/search?q=Egwuche%20Sylvester%20O."> Egwuche Sylvester O.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chronic Kidney Disease (CKD) is a significant cause of morbidity and mortality across developed and developing nations and is associated with increased risk. There are no existing electronic means of capturing and monitoring CKD in Nigeria. The work is aimed at developing a spatial data model that can be used to implement renal registries required for tracking and monitoring the spatial distribution of renal diseases by public health officers and patients. In this study, we have developed a spatial data model for a functional renal registry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20registry" title="renal registry">renal registry</a>, <a href="https://publications.waset.org/abstracts/search?q=health%20informatics" title=" health informatics"> health informatics</a>, <a href="https://publications.waset.org/abstracts/search?q=chronic%20kidney%20disease" title=" chronic kidney disease"> chronic kidney disease</a>, <a href="https://publications.waset.org/abstracts/search?q=interface" title=" interface"> interface</a> </p> <a href="https://publications.waset.org/abstracts/150377/development-of-a-spatial-data-for-renal-registry-in-nigeria-health-sector" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150377.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">212</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1069</span> Spectrum of Acute Kidney Injury in Obstetrics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Seema%20%20Chopra">Seema Chopra</a>, <a href="https://publications.waset.org/abstracts/search?q=Amandeep%20Kaur"> Amandeep Kaur</a>, <a href="https://publications.waset.org/abstracts/search?q=Vanita%20Suri"> Vanita Suri</a>, <a href="https://publications.waset.org/abstracts/search?q=Shalini%20Gainder"> Shalini Gainder</a>, <a href="https://publications.waset.org/abstracts/search?q=Minakshi%20Rohilla"> Minakshi Rohilla</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Acute kidney injury (AKI) associated with pregnancy is a serious medical complication which can lead to significant maternal as well as perinatal morbidity and mortality. Material and methods: This prospective observational study was carried out in the Obstetrics and Gynaecology department and dialysis unit of Nephrology department of PGIMER, Chandigarh from July 2013 to June 2014. Forty antenatal/postnatal/postabortal patients who fulfilled the AKIN criteria were enrolled in the study. All patients were followed up till 3 months postpartum. Results: Majority of the patients 23/40 (57.5%) with AKI presented in postpartum period, 14/40 (35%) developed AKI in antenatal period, and 3/40 (7.5%) were postabortal. AKI was attributable mostly to sepsis in 11/40 (27.5%) and PPH in 5/40 (12.5%). Hypertension and its complications causing AKI included eclampsia in 5/40 (12.5%) followed by 3/40 (7.5%) as HELLP syndrome and abruption placentae in 2/40(5%) patients. Three patients each (7.5%) had AFLP, TMA, and HEV as the cause of AKI. Renal replacement therapy in the form of hemodialysis was the treatment in majority of them (28 (70%)). After the acute event, 25 (62.5%) had complete recovery of their renal functions at 3 months follow up. Maternal mortality was seen in 25% (n=10) of the study patients. Conclusion: Timely initiation of RRT in patients with AKI associated with pregnancy has a good maternal outcome in the form of complete recovery of renal functions in 62.5% (25/40) of patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AKI" title="AKI">AKI</a>, <a href="https://publications.waset.org/abstracts/search?q=dialysis" title=" dialysis"> dialysis</a>, <a href="https://publications.waset.org/abstracts/search?q=hypertension" title=" hypertension"> hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=sepsis" title=" sepsis"> sepsis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20parameters" title=" renal parameters"> renal parameters</a> </p> <a href="https://publications.waset.org/abstracts/83127/spectrum-of-acute-kidney-injury-in-obstetrics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83127.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1068</span> The Effect of Enamel Surface Preparation on the Self-Etch Bonding of Orthodontic Tubes: An in Vitro Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fernandes%20A.%20C.%20B.%20C.%20J.">Fernandes A. C. B. C. J.</a>, <a href="https://publications.waset.org/abstracts/search?q=de%20Jesus%20V.%20C."> de Jesus V. C.</a>, <a href="https://publications.waset.org/abstracts/search?q=Sepideh%20N."> Sepideh N.</a>, <a href="https://publications.waset.org/abstracts/search?q=Vilela%20OFGG"> Vilela OFGG</a>, <a href="https://publications.waset.org/abstracts/search?q=Somarin%20K.%20K."> Somarin K. K.</a>, <a href="https://publications.waset.org/abstracts/search?q=Fran%C3%A7a%20R."> França R.</a>, <a href="https://publications.waset.org/abstracts/search?q=Pinheiro%20F.%20H.%20S.%20L."> Pinheiro F. H. S. L.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: The purpose of this study was to look at the effect of pre-treatment of enamel with pumice and/or 37% phosphoric acid on the shear bond strength (SBS) of orthodontic tubes bonded to enamel while simultaneously evaluating the efficacy of orthodontic tubes bonded by self-etch primer (SEP). Materials and Methods: 39 of the crown halves were divided into 3 groups at random. Group, I was the control group utilizing both prophy paste and the conventional double etching pre-treatment method. Group II excluded the use of prophy paste prior to double etching. Group III excluded the use of both prophy paste and double etching and only utilized SEP. Bond strength of the orthodontic tubes was measured by SBS. One way ANOVA and Tukey’s HSD test were used to compare SBS values between the three groups. The statistical significance was set to p<0.05. Results: The difference in SBS values of groups I (36.672 ± 9.315 Mpa), II (34.242 ± 9.986 Mpa), and III (39.055 ± 5.565) were not statistically significant (P<0.05). Conclusion: This study suggested that the use of prophy paste or pre-acid etch of the enamel surface did not provide a statistically significant difference in SBS between the three groups. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=shear%20bond%20strength" title="shear bond strength">shear bond strength</a>, <a href="https://publications.waset.org/abstracts/search?q=orthodontic%20bracket" title=" orthodontic bracket"> orthodontic bracket</a>, <a href="https://publications.waset.org/abstracts/search?q=self-etch%20primer" title=" self-etch primer"> self-etch primer</a>, <a href="https://publications.waset.org/abstracts/search?q=pumice" title=" pumice"> pumice</a>, <a href="https://publications.waset.org/abstracts/search?q=prophy" title=" prophy"> prophy</a> </p> <a href="https://publications.waset.org/abstracts/142849/the-effect-of-enamel-surface-preparation-on-the-self-etch-bonding-of-orthodontic-tubes-an-in-vitro-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142849.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">178</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1067</span> Joubert Syndrome in Children as Multicentric Screening in Ten Different Places in World</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bajraktarevic%20Adnan">Bajraktarevic Adnan</a>, <a href="https://publications.waset.org/abstracts/search?q=Djukic%20Branka"> Djukic Branka</a>, <a href="https://publications.waset.org/abstracts/search?q=Sporisevic%20Lutvo"> Sporisevic Lutvo</a>, <a href="https://publications.waset.org/abstracts/search?q=Krdzalic%20Zecevic%20Belma"> Krdzalic Zecevic Belma</a>, <a href="https://publications.waset.org/abstracts/search?q=Uzicanin%20Sajra"> Uzicanin Sajra</a>, <a href="https://publications.waset.org/abstracts/search?q=Hadzimuratovic%20Admir"> Hadzimuratovic Admir</a>, <a href="https://publications.waset.org/abstracts/search?q=Hadzimuratovic%20Hadzipasic%20Emina"> Hadzimuratovic Hadzipasic Emina</a>, <a href="https://publications.waset.org/abstracts/search?q=Abduzaimovic%20Alisa"> Abduzaimovic Alisa</a>, <a href="https://publications.waset.org/abstracts/search?q=Kustric%20Amer"> Kustric Amer</a>, <a href="https://publications.waset.org/abstracts/search?q=Suljevic%20Ismet"> Suljevic Ismet</a>, <a href="https://publications.waset.org/abstracts/search?q=Serafi%20Ismail"> Serafi Ismail</a>, <a href="https://publications.waset.org/abstracts/search?q=Tahmiscija%20Indira"> Tahmiscija Indira</a>, <a href="https://publications.waset.org/abstracts/search?q=Khatib%20Hakam"> Khatib Hakam</a>, <a href="https://publications.waset.org/abstracts/search?q=Semic%20Jusufagic%20Aida"> Semic Jusufagic Aida</a>, <a href="https://publications.waset.org/abstracts/search?q=Haas%20Helmut"> Haas Helmut</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladicic%20Aleksandra"> Vladicic Aleksandra</a>, <a href="https://publications.waset.org/abstracts/search?q=Aplenc%20Richard"> Aplenc Richard</a>, <a href="https://publications.waset.org/abstracts/search?q=Kadic%20Deovic%20Aida"> Kadic Deovic Aida</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Joubert syndrome has an autosomal recessive pattern of inheritance. It is referred as the brain malfunctioning and caused due to the underdevelopment of the cerebellar vermis. Associated conditions involving the eye, the kidney, and ocular disease are well described. Aims: Research helps us better understand this diseases, Joubert syndrome and can lead to advances in diagnosis and treatment. Methods: Different several conditions have been described in which the molar tooth sign and characteristics of Joubert syndrome in ten different places in the world. Carrier testing and diagnosis are available if one of these gene mutations has been identified in an affected family member. Results: Authors have described eleven cases during twenty years of Joubert syndrome. It is a clinically and genetically heterogeneous group of disorders characterized by hypoplasia of the cerebellar vermis with the characteristic neuroradiologic molar tooth sign, and accompanying neurologic symptoms, including dysregulation of breathing pattern and developmental delay. We made confirmation of diagnosis in twin sisters with Joubert syndrome with renal anomalies. Ocular symptoms have existed in seven cases (63.64%) from total eleven. Eleven cases were different sex, five boys (45.45%) and six girls (54.44%). Conclusions: Joubert syndrome is inherited as an autosomal recessive genetic disorder with several features of the disease. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Joubert%20syndrome" title="Joubert syndrome">Joubert syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=cerebellooculorenal%20syndrome" title=" cerebellooculorenal syndrome"> cerebellooculorenal syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=autosomal%20recessive%20genetic%20disorder%20%28ARGD%29" title=" autosomal recessive genetic disorder (ARGD)"> autosomal recessive genetic disorder (ARGD)</a>, <a href="https://publications.waset.org/abstracts/search?q=children" title=" children"> children</a> </p> <a href="https://publications.waset.org/abstracts/70523/joubert-syndrome-in-children-as-multicentric-screening-in-ten-different-places-in-world" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70523.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">278</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1066</span> Improving the Biomechanical Resistance of a Treated Tooth via Composite Restorations Using Optimised Cavity Geometries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Behzad%20Babaei">Behzad Babaei</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Gangadhara%20Prusty"> B. Gangadhara Prusty</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The objective of this study is to assess the hypotheses that a restored tooth with a class II occlusal-distal (OD) cavity can be strengthened by designing an optimized cavity geometry, as well as selecting the composite restoration with optimized elastic moduli when there is a sharp de-bonded edge at the interface of the tooth and restoration. Methods: A scanned human maxillary molar tooth was segmented into dentine and enamel parts. The dentine and enamel profiles were extracted and imported into a finite element (FE) software. The enamel rod orientations were estimated virtually. Fifteen models for the restored tooth with different cavity occlusal depths (1.5, 2, and 2.5 mm) and internal cavity angles were generated. By using a semi-circular stone part, a 400 N load was applied to two contact points of the restored tooth model. The junctions between the enamel, dentine, and restoration were considered perfectly bonded. All parts in the model were considered homogeneous, isotropic, and elastic. The quadrilateral and triangular elements were employed in the models. A mesh convergence analysis was conducted to verify that the element numbers did not influence the simulation results. According to the criteria of a 5% error in the stress, we found that a total element number of over 14,000 elements resulted in the convergence of the stress. A Python script was employed to automatically assign 2-22 GPa moduli (with increments of 4 GPa) for the composite restorations, 18.6 GPa to the dentine, and two different elastic moduli to the enamel (72 GPa in the enamel rods’ direction and 63 GPa in perpendicular one). The linear, homogeneous, and elastic material models were considered for the dentine, enamel, and composite restorations. 108 FEA simulations were successively conducted. Results: The internal cavity angles (α) significantly altered the peak maximum principal stress at the interface of the enamel and restoration. The strongest structures against the contact loads were observed in the models with α = 100° and 105. Even when the enamel rods’ directional mechanical properties were disregarded, interestingly, the models with α = 100° and 105° exhibited the highest resistance against the mechanical loads. Regarding the effect of occlusal cavity depth, the models with 1.5 mm depth showed higher resistance to contact loads than the model with thicker cavities (2.0 and 2.5 mm). Moreover, the composite moduli in the range of 10-18 GPa alleviated the stress levels in the enamel. Significance: For the class II OD cavity models in this study, the optimal geometries, composite properties, and occlusal cavity depths were determined. Designing the cavities with α ≥100 ̊ was significantly effective in minimizing peak stress levels. The composite restoration with optimized properties reduced the stress concentrations on critical points of the models. Additionally, when more enamel was preserved, the sturdier enamel-restoration interface against the mechanical loads was observed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dental%20composite%20restoration" title="dental composite restoration">dental composite restoration</a>, <a href="https://publications.waset.org/abstracts/search?q=cavity%20geometry" title=" cavity geometry"> cavity geometry</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20approach" title=" finite element approach"> finite element approach</a>, <a href="https://publications.waset.org/abstracts/search?q=maximum%20principal%20stress" title=" maximum principal stress"> maximum principal stress</a> </p> <a href="https://publications.waset.org/abstracts/152081/improving-the-biomechanical-resistance-of-a-treated-tooth-via-composite-restorations-using-optimised-cavity-geometries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152081.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">101</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1065</span> Navigating the Complexity of Guillain-Barré Syndrome and Miller Fisher Syndrome Overlap Syndrome: A Pediatric Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kamal%20Chafiq">Kamal Chafiq</a>, <a href="https://publications.waset.org/abstracts/search?q=Youssef%20Hadzine"> Youssef Hadzine</a>, <a href="https://publications.waset.org/abstracts/search?q=Adel%20Elmekkaoui"> Adel Elmekkaoui</a>, <a href="https://publications.waset.org/abstracts/search?q=Othmane%20Benlenda"> Othmane Benlenda</a>, <a href="https://publications.waset.org/abstracts/search?q=Houssam%20Rajad"> Houssam Rajad</a>, <a href="https://publications.waset.org/abstracts/search?q=Soukaina%20Wakrim"> Soukaina Wakrim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hicham%20Nassik"> Hicham Nassik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Guillain-Barré syndrome/Miller Fishe syndrome (GBS/MFS) overlap syndrome is an extremely rare variant of Guillain-Barré syndrome (GBS) in which Miller Fisher syndrome (MFS) coexists with other characteristics of GBS, such as limb weakness, paresthesia, and facial paralysis. We report the clinical case of a 12-year-old patient, with no pathological history, who acutely presents with ophthalmoplegia, areflexia, facial diplegia, and swallowing and phonation disorders, followed by progressive, descending, and symmetrical paresis affecting first the upper limbs and then the lower limbs. An albuminocytological dissociation was found in the cerebrospinal fluid study. Magnetic resonance imaging of the spinal cord showed enhancement and thickening of the cauda equina roots. The patient was treated with immunoglobulins with a favorable clinical outcome. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Guillain-Barr%C3%A9%20syndrome" title="Guillain-Barré syndrome">Guillain-Barré syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=Miller%20Fisher%20syndrome" title=" Miller Fisher syndrome"> Miller Fisher syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=overlap%20syndrome" title=" overlap syndrome"> overlap syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-GQ1b%20antibodies" title=" anti-GQ1b antibodies"> anti-GQ1b antibodies</a> </p> <a href="https://publications.waset.org/abstracts/183387/navigating-the-complexity-of-guillain-barre-syndrome-and-miller-fisher-syndrome-overlap-syndrome-a-pediatric-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183387.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">77</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1064</span> Management of Renal Malignancies with IVC Thrombus: Our Experience</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sujeet%20Poudyal">Sujeet Poudyal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Renal cell carcinoma is the most common malignancy associated with Inferior vena cava (IVC) thrombosis. Radical nephrectomy with tumor thrombectomy provides durable cancer-free survival. Other renal malignancies like Wilms’ tumors are also associated with IVC thrombus. We describe our experience with the management of renal malignancies associated with IVC thrombus. Methods: This prospective study included 28 patients undergoing surgery for renal malignancies associated with IVC thrombus from February 2017 to March 2023. Demographics of patients, types of renal malignancy, level of IVC thrombus, intraoperative details, need for venovenous bypass, cardiopulmonary bypass and postoperative outcomes were all documented. Results: Out of a total of 28 patients, 24 patients had clear cell Renal Cell Carcinoma,1 had renal osteosarcoma and 3 patients had Wilms tumor. The levels. of thrombus were II in eight, III in seven, and IV in six patients. The mean age of RCC was 62.81±10.2 years, renal osteosarcoma was 26 years and Wilms tumor was 23 years. There was a need for venovenous bypass in four patients and cardiopulmonary bypass in four patients, and the Postoperative period was uneventful in most cases except for two mortalities, one in Level III due to pneumonia and one in Level IV due to sepsis. All cases followed up till now have no local recurrence and metastasis except one case of RCC with Level IV IVC thrombus, which presented with paraaortic nodal recurrence and is currently managed with sunitinib. Conclusion: The complexity in the management of renal malignancy with IVC thrombus increases with the level of IVC thrombus. As radical nephrectomy with tumor thrombectomy provides durable cancer-free survival in most cases, the surgery should be undertaken in an expert and experienced setup with a strong cardiovascular backup to minimize morbidity and mortality associated with the procedure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20malignancy" title="renal malignancy">renal malignancy</a>, <a href="https://publications.waset.org/abstracts/search?q=IVC%20thrombus" title=" IVC thrombus"> IVC thrombus</a>, <a href="https://publications.waset.org/abstracts/search?q=radical%20nephrectomy%20with%20tumor%20thrombectomy" title=" radical nephrectomy with tumor thrombectomy"> radical nephrectomy with tumor thrombectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20cell%20carcinoma" title=" renal cell carcinoma"> renal cell carcinoma</a> </p> <a href="https://publications.waset.org/abstracts/168963/management-of-renal-malignancies-with-ivc-thrombus-our-experience" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/168963.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">62</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1063</span> Bifid Ureters: Arising Directly from the Separate Calyces and Renal Pelvis of the Kidney: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yuri%20Seu">Yuri Seu</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyun%20Jin%20Park"> Hyun Jin Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Jin%20Seo%20Park"> Jin Seo Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Yong-Suk%20Moon"> Yong-Suk Moon</a>, <a href="https://publications.waset.org/abstracts/search?q=HongtaeKim"> HongtaeKim</a>, <a href="https://publications.waset.org/abstracts/search?q=Mi-Sun%20Hur"> Mi-Sun Hur</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present case report describes bifid ureters arising directly from the separate calyces and renal pelvis of the kidney. It was a single common ureter leading away from the bladder, which was separated into incompletely duplicated ureters near the level of the anterior superior iliac supine. These two branches then entered the left kidney through their own courses. Each ureter traveled anterior and posterior to the renal vein, respectively. These two ureters formed a Y-shaped pattern. One ureter coursed anterior to the renal vein with shorter length, and it terminated at the renal pelvis that was divided into major calices in approximately lower two thirds of the kidney. The other ureter coursed posterior to the renal vein with longer length, terminating at approximately the upper third of the kidney. The renal calices in the upper third of the kidney were directly connected to the posterior ureter, whereas the other major calices in the lower two thirds of the kidney formed the renal pelvis connecting to the anterior ureter. Thus, convergence of the major calices was separated according to the terminations of two ureters. These anomalous ureters were traced to the calices of the kidney, thereby providing a reference of a rare variation of the ureter. The bifid ureters arising from the separate calyces and renal pelvis should be considered by radiologists when evaluating images and diagnosing possible complications of these anomalies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bifid%20ureters" title="bifid ureters">bifid ureters</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=major%20calices" title=" major calices"> major calices</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20pelvis" title=" renal pelvis"> renal pelvis</a> </p> <a href="https://publications.waset.org/abstracts/167715/bifid-ureters-arising-directly-from-the-separate-calyces-and-renal-pelvis-of-the-kidney-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167715.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">86</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1062</span> Renal Complications in Patients with Falciparum Malaria </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saira%20Baloch">Saira Baloch</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohsin%20Ali%20Baloch"> Mohsin Ali Baloch </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Malaria is a potentially life-threatening disease and also a major public health problem in Pakistan. Renal failure is an emerging problem correlated with morbidity and mortality, however can be diagnosed and treated in the early stages. Objectives: To elucidate the biochemical renal parameters in patients with falciparum malaria and comparison with healthy control subjects. Method: 80 patients, who were diagnosed to be affected by falciparum malaria. Detailed history, general physical and systemic examination and necessary pathological, biochemical renal laboratory parameters and investigations were done. Results: Among the 80 patients, 43 were males and 37 were females. All patients were infected with P. falciparum. All patients had increased serum creatinine and urea levels and urine output of less than 400 ml/day were categorized as suffering from renal failure. Conclusion: Patients infected with P. falciparum are at an increased risk of developing renal failure when compared to patients infected with other complications. P. vivax has massive potential to cause life threatening complications and even death. Further research is required to understand the exact pathogenesis of various complications encountered in vivax malaria. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=falciparum%20malaria" title="falciparum malaria">falciparum malaria</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20failure" title=" renal failure"> renal failure</a>, <a href="https://publications.waset.org/abstracts/search?q=biochemical%20parameters" title=" biochemical parameters"> biochemical parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=pathogenesis" title=" pathogenesis"> pathogenesis</a> </p> <a href="https://publications.waset.org/abstracts/14798/renal-complications-in-patients-with-falciparum-malaria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14798.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">387</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1061</span> Atypical Clinical Presentation of Wallenberg Syndrome from Acute Right Lateral Medullary Infarct in a 37 Year Old Female</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sweta%20Das">Sweta Das</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This case report highlights the atypical clinical manifestation of ipsilateral head, neck, shoulder, and eye pain with erythema and edema of right eyelid and conjunctiva, along with typical presentation of right sided Horner’s syndrome in a 37-year-old female, who was correctly diagnosed with Wallenberg syndrome due to collaborative effort from optometry, primary care, emergency, and neurology specialties in medicine. Horner’s syndrome is present in 75% of patients with Wallenberg syndrome. Given that patients with Wallenberg syndrome often first present to the Emergency Department with a vast variety of non-specific symptoms, and a normal MRI, a delayed diagnosis is common. Therefore, a collaborative effort between emergency department, optometry, primary care, and neurology is essential in correctly diagnosing Wallenberg’s syndrome in a timely manner. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=horner%27s%20syndrome" title="horner&#039;s syndrome">horner&#039;s syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=stroke" title=" stroke"> stroke</a>, <a href="https://publications.waset.org/abstracts/search?q=wallenberg%20syndrome" title=" wallenberg syndrome"> wallenberg syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=lateropulsion%20of%20eyes" title=" lateropulsion of eyes"> lateropulsion of eyes</a> </p> <a href="https://publications.waset.org/abstracts/177877/atypical-clinical-presentation-of-wallenberg-syndrome-from-acute-right-lateral-medullary-infarct-in-a-37-year-old-female" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/177877.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">60</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1060</span> Renal Transplant, Pregnancy, and Complications: A Literature Review </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sara%20Iqbal">Sara Iqbal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction:Renal transplant is increasingly one of the most popular transplants within the UK; with an aging population along with obesity epidemic we are witnessing increasing rates of diabetes – one of the commonest indications for renal transplant. However, the demand is far greater than supply. Many donors are provided by women of child-bearing age; however the long-term effects are still uncertain. Aim:Determine pregnancy outcomes and complications of women of child-bearing age following renal donation. Methods: A review of the current available literature was preformed using MEDLINE and EMBASE up to 2014. Search criteria included key terms such as pregnancy outcome post-renal donor, pregnancy outcomes and complications. Relevant articles were selected based on pure methodological medical research, after careful analysis, they were recorded within this review. Results: Out of 1141 women involved in transplant studies, 574 pregnancies reported having donated a single-renal donor prior to pregnancy. Of which a staggering miscarriage rate 32.4% (n=186) was reported, amongst this other complications included gestational hypertension of 10% (n=59) and gestational diabetes 2.3% (n=13). Other significantly noted complications included chronic hypertension, low-birth weights, and pregnancy-related death. Conclusions: After unilateral renal donor transplant, haemodynamics change along with pregnancy, predisposing women to developing several complications compared to pregnancies with no history any renal-donor transplant. Despite this, further investigation is required in order to accurately determine the safety of renal-donors in women of child-bearing age. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20transplant" title="renal transplant">renal transplant</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=complications" title=" complications"> complications</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20and%20health%20sciences" title=" medical and health sciences "> medical and health sciences </a> </p> <a href="https://publications.waset.org/abstracts/17993/renal-transplant-pregnancy-and-complications-a-literature-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17993.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1059</span> The Effect of the Combination of Mouthwash and Saliva Substitutes on Tooth Erosion: An in Vitro Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Young-Eun%20Jang">Young-Eun Jang</a>, <a href="https://publications.waset.org/abstracts/search?q=Mi-Hye%20Ma"> Mi-Hye Ma</a>, <a href="https://publications.waset.org/abstracts/search?q=Yemi%20Kim"> Yemi Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As the elderly population increases, the number of patients complaining of dry mouth is also increasing. Elderly people often use mouthwash to prevent periodontal disease. Mouthwash and saliva substitutes with low pH were reported to be able to cause enamel erosion. To the best of our knowledge, there have been no studies showing the effect of mouthwash on patients using saliva substitutes. Therefore, the purpose of this study was to evaluate the effect of the use of mouthwash in combination with saliva substitutes on tooth erosion using a quantitative light-induced fluorescence-digital (QLF-D) system. A total of 96 bovine specimens were embedded in putty blocks and randomly allocated to the following groups with n = 12 each: Group 1, application of mouthwash; Group 2, application of saliva substitutes; Group 3, application of saliva substitutes in combination with mouthwash; and control group, application of saline. The bovine samples were eroded using a demineralization solution and then saliva substitutes and mouthwash were applied according to the groups for 2 weeks. For saliva substitutes, three different products were used; Oasis (Oasis Consumer Health, Cleveland, OH, USA), Xeromia solution (Osstem Pharma Co., Seoul, Korea), and Drymund gel (Dong-A Pharma Co., Seoul, Korea). The pH values of the saliva substitutes were determined using a pH meter. Loss of enamel and root dentin was measured using the QLF-D system immediately after demineralization on the 3rd, 7th, and 14th days. The data were analyzed using repeated measures ANOVA followed by Tukey’s post hoc tests (p < 0.05). Mineral loss in enamel and root dentin was detected when mouthwash and saliva substitutes were used alone, respectively (p < 0.05). Also, when mouthwash was used with saliva substitutes, the mineral loss was observed in enamel and root dentin (p < 0.05). The use of Xeromia and Drymund gel increased mineral loss of enamel significantly compared to the use of Oasis (p < 0.05). However, when Drymund gel and Xeromia were used in combination with mouthwash, mineral loss of enamel was significantly reduced compared to when they were used alone (p < 0.05). The pH values of Drymund gel, Xeromia, Oasis, and mouthwash were 5.5, 5.52, 6.2, and 6.37, respectively. Based on these results, it can be concluded that the use of mouthwash with a higher pH value than that of saliva substitutes could help patients suffering from xerostomia avoid the risk of dental erosion. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=saliva%20substitute" title="saliva substitute">saliva substitute</a>, <a href="https://publications.waset.org/abstracts/search?q=mouthwash" title=" mouthwash"> mouthwash</a>, <a href="https://publications.waset.org/abstracts/search?q=tooth%20erosion" title=" tooth erosion"> tooth erosion</a>, <a href="https://publications.waset.org/abstracts/search?q=dry%20mouth" title=" dry mouth"> dry mouth</a> </p> <a href="https://publications.waset.org/abstracts/156425/the-effect-of-the-combination-of-mouthwash-and-saliva-substitutes-on-tooth-erosion-an-in-vitro-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156425.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">89</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1058</span> Development of an Experimental Model of Diabetes Co-Existing with Metabolic Syndrome in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rajesh%20Kumar%20Suman">Rajesh Kumar Suman</a>, <a href="https://publications.waset.org/abstracts/search?q=Ipseeta%20Ray%20Mohanty"> Ipseeta Ray Mohanty</a>, <a href="https://publications.waset.org/abstracts/search?q=Manjusha%20K.%20Borde"> Manjusha K. Borde</a>, <a href="https://publications.waset.org/abstracts/search?q=Ujjawala%20maheswari"> Ujjawala maheswari</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20A.%20Deshmukh"> Y. A. Deshmukh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Metabolic syndrome encompasses cluster of risk factors for cardiovascular disease which includes abdominal obesity, dyslipidemia, hypertension, and hyperglycemia. The incidence of metabolic syndrome is on the rise globally. Objective: The present study was designed to develop a unique animal model that will mimic the pathological features seen in a large pool of individuals with diabetes and metabolic syndrome; suitable for pharmacological screening of drugs beneficial in this condition. Material and Methods: A combination of high fat diet (HFD) and low dose of streptozotocin (STZ) at 30, 35 and 40 mg/kg was used to induce metabolic syndrome co-existing with diabetes mellitus in Wistar rats. Results: The 40 mg/kg STZ produced sustained hyperglycemia and the dose was thus selected for our study to induce diabetes mellitus. Rat fed HFD (HF-DC) group showed significant (p < 0.001) increase in body weight on 4th and 7th week as compared with NC (Normal Control) group rats. However, the increase in body weight of HF-DC group rats was not sustained at the end of 10th weeks. Various components of metabolic syndrome such as dyslipidemia {(Increased Triglyceride, total Cholesterol, LDL Cholesterol and decreased HDL Cholesterol)}, diabetes mellitus (Blood Glucose, HbA1c, Serum Insulin, C-peptide), hypertension {Systolic Blood pressure (p < 0.001)} were mimicked in the developed model of metabolic syndrome co existing with diabetes mellitus. In addition significant cardiac injury as indicated by CPK-MB levels, artherogenic index, hs-CRP. The decline in hepatic function {(p < 0.01) increase in the level of SGPT (U/L)} and renal function {(increase in creatinine levels (p < 0.01)} when compared to NC group rats. The histopathological assessment confirmed presence of edema, necrosis and inflammation in Heart, Pancreas, Liver and Kidney of HFD-DC group as compared to NC. Conclusion: The present study has developed a unique rodent model of metabolic syndrome; with diabetes as an essential component. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes" title="diabetes">diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolic%20syndrome" title=" metabolic syndrome"> metabolic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=high%20fat%20diet" title=" high fat diet"> high fat diet</a>, <a href="https://publications.waset.org/abstracts/search?q=streptozotocin" title=" streptozotocin"> streptozotocin</a>, <a href="https://publications.waset.org/abstracts/search?q=rats" title=" rats"> rats</a> </p> <a href="https://publications.waset.org/abstracts/39474/development-of-an-experimental-model-of-diabetes-co-existing-with-metabolic-syndrome-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39474.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">348</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1057</span> Characterization of White Spot Lesion Using Focused Ion Beam - Scanning Electron Microscopy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Malihe%20Moeinin">Malihe Moeinin</a>, <a href="https://publications.waset.org/abstracts/search?q=Robert%20Hill"> Robert Hill</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferranti%20Wong"> Ferranti Wong</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: A white spot lesion (WSL) is defined as subsurface enamel porosity from carious demineralisation on the smooth surfaces of the tooth. It appears as a milky white opacity. Lesions shown an apparently intact surface layer, followed underneath by the more porous lesion body. The small pores within the body of the lesion act as diffusion pathway for both acids and minerals, so allowing the demineralisation of enamel to occur at the advancing front of the lesion. Objectives: The objective is to mapthe porosity and its size on WSL with Focused Ion Bean- Scanning Electron Microscopy (FIB-SEM) Method: The basic method used for FIB-SEM consisted of depositing a one micron thick layer of platinum over 25μmx 25μm of the interest region of enamel. Then, making a rough cut (25μmx 5μmx 20μm) with 3nA current and 30Kv was applied with the help of drift suppression (DS), using a standard “cross-sectional” cutting pattern, which ended at the front of the deposited platinum layer. Two adjacent areas (25μmx 5μmx 20μm) on the both sides of the platinum layer were milled under the same conditions. Subsequent, cleaning cross-sections were applied to polish the sub-surface edge of interest running perpendicular to the surface. The "slice and view" was carried out overnight for milling almost 700 slices with 2Kv and 4nA and taking backscattered (BS) images. Then, images were imported into imageJ and analysed. Results: The prism structure is clearly apparent on FIB-SEM slices of WSL with the dissolution of prism boundaries as well as internal porosity within the prism itself. Porosity scales roughly 100-400nm, which is comparable to the light wavelength (500nm). Conclusion: FIB-SEM is useful to characterize the porosity of WSL and it clearly shows the difference between WSL and normal enamel. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=white%20spot%20lesion" title="white spot lesion">white spot lesion</a>, <a href="https://publications.waset.org/abstracts/search?q=FIB-SEM" title=" FIB-SEM"> FIB-SEM</a>, <a href="https://publications.waset.org/abstracts/search?q=enamel%20porosity" title=" enamel porosity"> enamel porosity</a>, <a href="https://publications.waset.org/abstracts/search?q=porosity" title=" porosity"> porosity</a> </p> <a href="https://publications.waset.org/abstracts/157409/characterization-of-white-spot-lesion-using-focused-ion-beam-scanning-electron-microscopy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/157409.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1056</span> Assessment of Wastewater Reuse Potential for an Enamel Coating Industry</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Guclu%20Insel">Guclu Insel</a>, <a href="https://publications.waset.org/abstracts/search?q=Efe%20Gumuslu"> Efe Gumuslu</a>, <a href="https://publications.waset.org/abstracts/search?q=Gulten%20Yuksek"> Gulten Yuksek</a>, <a href="https://publications.waset.org/abstracts/search?q=Nilay%20Sayi%20Ucar"> Nilay Sayi Ucar</a>, <a href="https://publications.waset.org/abstracts/search?q=Emine%20Ubay%20Cokgor"> Emine Ubay Cokgor</a>, <a href="https://publications.waset.org/abstracts/search?q=Tugba%20Olmez%20Hanci"> Tugba Olmez Hanci</a>, <a href="https://publications.waset.org/abstracts/search?q=Didem%20Okutman%20Tas"> Didem Okutman Tas</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatos%20Germirli%20Babuna"> Fatos Germirli Babuna</a>, <a href="https://publications.waset.org/abstracts/search?q=Derya%20Firat%20Ertem"> Derya Firat Ertem</a>, <a href="https://publications.waset.org/abstracts/search?q=Okmen%20Yildirim"> Okmen Yildirim</a>, <a href="https://publications.waset.org/abstracts/search?q=Ozge%20Erturan"> Ozge Erturan</a>, <a href="https://publications.waset.org/abstracts/search?q=Betul%20Kirci"> Betul Kirci</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In order to eliminate water scarcity problems, effective precautions must be taken. Growing competition for water is increasingly forcing facilities to tackle their own water scarcity problems. At this point, application of wastewater reclamation and reuse results in considerable economic advantageous. In this study, an enamel coating facility, which is one of the high water consumed facilities, is evaluated in terms of its wastewater reuse potential. Wastewater reclamation and reuse can be defined as one of the best available techniques for this sector. Hence, process and pollution profiles together with detailed characterization of segregated wastewater sources are appraised in a way to find out the recoverable effluent streams arising from enamel coating operations. Daily, 170 m<sup>3</sup> of process water is required and 160 m<sup>3</sup> of wastewater is generated. The segregated streams generated by two enamel coating processes are characterized in terms of conventional parameters. Relatively clean segregated wastewater streams (reusable wastewaters) are separately collected and experimental treatability studies are conducted on it. The results reflected that the reusable wastewater fraction has an approximate amount of 110 m<sup>3</sup>/day that accounts for 68% of the total wastewaters. The need for treatment applicable on reusable wastewaters is determined by considering water quality requirements of various operations and characterization of reusable wastewater streams. Ultra-filtration (UF), Nano-filtration (NF) and Reverse Osmosis (RO) membranes are subsequently applied on reusable effluent fraction. Adequate organic matter removal is not obtained with the mentioned treatment sequence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=enamel%20coating" title="enamel coating">enamel coating</a>, <a href="https://publications.waset.org/abstracts/search?q=membrane" title=" membrane"> membrane</a>, <a href="https://publications.waset.org/abstracts/search?q=reuse" title=" reuse"> reuse</a>, <a href="https://publications.waset.org/abstracts/search?q=wastewater%20reclamation" title=" wastewater reclamation"> wastewater reclamation</a> </p> <a href="https://publications.waset.org/abstracts/44839/assessment-of-wastewater-reuse-potential-for-an-enamel-coating-industry" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44839.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">328</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1055</span> Comparison of the Classification of Cystic Renal Lesions Using the Bosniak Classification System with Contrast Enhanced Ultrasound and Magnetic Resonance Imaging to Computed Tomography: A Prospective Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dechen%20Tshering%20Vogel">Dechen Tshering Vogel</a>, <a href="https://publications.waset.org/abstracts/search?q=Johannes%20T.%20Heverhagen"> Johannes T. Heverhagen</a>, <a href="https://publications.waset.org/abstracts/search?q=Bernard%20Kiss"> Bernard Kiss</a>, <a href="https://publications.waset.org/abstracts/search?q=Spyridon%20Arampatzis"> Spyridon Arampatzis </a> </p> <p class="card-text"><strong>Abstract:</strong></p> In addition to computed tomography (CT), contrast enhanced ultrasound (CEUS), and magnetic resonance imaging (MRI) are being increasingly used for imaging of renal lesions. The aim of this prospective study was to compare the classification of complex cystic renal lesions using the Bosniak classification with CEUS and MRI to CT. Forty-eight patients with 65 cystic renal lesions were included in this study. All participants signed written informed consent. The agreement between the Bosniak classifications of complex renal lesions ( ≥ BII-F) on CEUS and MRI were compared to that of CT and were tested using Cohen’s Kappa. Sensitivity, specificity, positive and negative predictive values (PPV/NPV) and the accuracy of CEUS and MRI compared to CT in the detection of complex renal lesions were calculated. Twenty-nine (45%) out of 65 cystic renal lesions were classified as complex using CT. The agreement between CEUS and CT in the classification of complex cysts was fair (agreement 50.8%, Kappa 0.31), and was excellent between MRI and CT (agreement 93.9%, Kappa 0.88). Compared to CT, MRI had a sensitivity of 96.6%, specificity of 91.7%, a PPV of 54.7%, and an NPV of 54.7% with an accuracy of 63.1%. The corresponding values for CEUS were sensitivity 100.0%, specificity 33.3%, PPV 90.3%, and NPV 97.1% with an accuracy 93.8%. The classification of complex renal cysts based on MRI and CT scans correlated well, and MRI can be used instead of CT for this purpose. CEUS can exclude complex lesions, but due to higher sensitivity, cystic lesions tend to be upgraded. However, it is useful for initial imaging, for follow up of lesions and in those patients with contraindications to CT and MRI. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bosniak%20classification" title="Bosniak classification">Bosniak classification</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=contrast%20enhanced%20ultrasound" title=" contrast enhanced ultrasound"> contrast enhanced ultrasound</a>, <a href="https://publications.waset.org/abstracts/search?q=cystic%20renal%20lesions" title=" cystic renal lesions"> cystic renal lesions</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20resonance%20imaging" title=" magnetic resonance imaging"> magnetic resonance imaging</a> </p> <a href="https://publications.waset.org/abstracts/111885/comparison-of-the-classification-of-cystic-renal-lesions-using-the-bosniak-classification-system-with-contrast-enhanced-ultrasound-and-magnetic-resonance-imaging-to-computed-tomography-a-prospective-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/111885.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">143</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1054</span> Behavioral Problems Among Down Syndrome Children in the Special Education Complex Peshawar</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Huma%20Atta">Huma Atta</a>, <a href="https://publications.waset.org/abstracts/search?q=Ishrat%20Rehman"> Ishrat Rehman</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Umair"> Muhammad Umair</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To find out the effectiveness of Dr. Stein behavioural modification strategies among Down syndrome children’s behavioural problems. Material & Methods: We took a group of individuals (aged 8-16) having Down syndrome from national special education complex, Peshawar. They were assessed through the behavioural problem index to give us an idea on their behaviour problems, those with a behavioural problem were kept in therapy for further sessions to help them improve. Results: A treatment plan was made according to the extracted behavioural problems of Down syndrome children. Dr. Stein recommended behavioural modification treatment strategies were used for behavioural modification of Down syndrome children (Routine, reward, choice, redirection and consistency). Pre-intervention (M=69.11, SD=6.27) and post-intervention (M=61.33, SD=6.51) conditions; t (8) =2.70, p=0.027. Conclusion: After the successful completion of 9 sessions with Down syndrome children, their behavioural problems were reassessed. Results indicated that Dr. Stein behavioural modification strategy is an effective treatment plan for the modification of behavioural problems among Down syndrome children. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=behavior" title="behavior">behavior</a>, <a href="https://publications.waset.org/abstracts/search?q=down%20syndrome" title=" down syndrome"> down syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=treatment" title=" treatment"> treatment</a>, <a href="https://publications.waset.org/abstracts/search?q=strategies" title=" strategies"> strategies</a> </p> <a href="https://publications.waset.org/abstracts/193314/behavioral-problems-among-down-syndrome-children-in-the-special-education-complex-peshawar" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193314.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">10</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1053</span> The Association of Cone-Shaped Epiphysis and Poland Syndrome: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Alqattan">Mohammad Alqattan</a>, <a href="https://publications.waset.org/abstracts/search?q=Tala%20Alkhunani"> Tala Alkhunani</a>, <a href="https://publications.waset.org/abstracts/search?q=Reema%20Al"> Reema Al</a>, <a href="https://publications.waset.org/abstracts/search?q=Aldawish"> Aldawish</a>, <a href="https://publications.waset.org/abstracts/search?q=Felwa%20Almurshard"> Felwa Almurshard</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdullah%20Alzahrani"> Abdullah Alzahrani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> : Poland’s Syndrome is a congenital anomaly with two clinical features : unilateral agenesis of the pectoralis major and ipsilateral hand symbrachydactyly. Case presentation: We report a rare case of bilateral Poland’s syndrome with several unique features. Discussion: Poland’s syndrome is thought to be due to a vascular insult to the subclavian axis around the 6th week of gestation. Our patient has multiple rare and unique features of Poland’s syndrome. Conclusion: To our best knowledge, for the first time in the literature we associate Poland’s syndrome with cone-shaped epiphysis of the metacarpals of all fingers. Bilaterality, cleft hand deformity, and dextrocardia, were also rare features in our patient. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Poland%27s%20syndrome" title="Poland&#039;s syndrome">Poland&#039;s syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=cleft%20hand%20deformity" title=" cleft hand deformity"> cleft hand deformity</a>, <a href="https://publications.waset.org/abstracts/search?q=bilaterality" title=" bilaterality"> bilaterality</a>, <a href="https://publications.waset.org/abstracts/search?q=dextrocardia" title=" dextrocardia"> dextrocardia</a>, <a href="https://publications.waset.org/abstracts/search?q=cone-shaped%20epiphysis" title=" cone-shaped epiphysis"> cone-shaped epiphysis</a> </p> <a href="https://publications.waset.org/abstracts/157595/the-association-of-cone-shaped-epiphysis-and-poland-syndrome-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/157595.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">129</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1052</span> Joubert Syndrome and Related Disorders: A Single Center Experience</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ali%20Al%20Orf">Ali Al Orf</a>, <a href="https://publications.waset.org/abstracts/search?q=Khawaja%20Bilal%20Waheed"> Khawaja Bilal Waheed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background and objective: Joubert syndrome (JS) is a rare, autosomal-recessive condition. Early recognition is important for management and counseling. Magnetic resonance imaging (MRI) can help in diagnosis. Therefore, we sought to evaluate clinical presentation and MRI findings in Joubert syndrome and related disorders. Method: A retrospective review of genetically proven cases of Joubert syndromes and related disorders was reviewed for their clinical presentation, demographic information, and magnetic resonance imaging findings in a period of the last 10 years. Two radiologists documented magnetic resonance imaging (MRI) findings. The presence of hypoplasia of the cerebellar vermis with hypoplasia of the superior cerebellar peduncle resembling the “Molar Tooth Sign” in the mid-brain was documented. Genetic testing results were collected to label genes linked to the diagnoses. Results: Out of 12 genetically proven JS cases, most were females (9/12), and nearly all presented with hypotonia, ataxia, developmental delay, intellectual impairment, and speech disorders. 5/12 children presented at age of 1 or below. The molar tooth sign was seen in 10/12 cases. Two cases were associated with other brain findings. Most of the cases were found associated with consanguineous marriage Conclusion and discussion: The molar tooth sign is a frequent and reliable sign of JS and related disorders. Genes related to defective cilia result in malfunctioning in the retina, renal tubule, and neural cell migration, thus producing heterogeneous syndrome complexes known as “ciliopathies.” Other ciliopathies like Senior-Loken syndrome, Bardet Biedl syndrome, and isolated nephronophthisis must be considered as the differential diagnosis of JS. The main imaging findings are the partial or complete absence of the cerebellar vermis, hypoplastic cerebellar peduncles (giving MTS), and (bat-wing appearance) fourth ventricular deformity. LimitationsSingle-center, small sample size, and retrospective nature of the study were a few of the study limitations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Joubart%20syndrome" title="Joubart syndrome">Joubart syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20resonance%20imaging" title=" magnetic resonance imaging"> magnetic resonance imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=molar%20tooth%20sign" title=" molar tooth sign"> molar tooth sign</a>, <a href="https://publications.waset.org/abstracts/search?q=hypotonia" title=" hypotonia"> hypotonia</a> </p> <a href="https://publications.waset.org/abstracts/158137/joubert-syndrome-and-related-disorders-a-single-center-experience" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158137.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info 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