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uHealth</span> <span class="articles-number" data-v-575455fb>2760 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://ojphi.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>Online Journal of Public Health Informatics</span> <span class="articles-number" data-v-575455fb>1723 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://publichealth.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Public Health and Surveillance</span> <span class="articles-number" data-v-575455fb>1708 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://medinform.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Medical Informatics</span> <span class="articles-number" data-v-575455fb>1460 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://mental.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Mental Health</span> <span class="articles-number" data-v-575455fb>1116 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://humanfactors.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Human Factors</span> <span class="articles-number" data-v-575455fb>865 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://games.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Serious Games</span> <span class="articles-number" data-v-575455fb>664 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://mededu.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Medical Education</span> <span class="articles-number" data-v-575455fb>590 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://www.iproc.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>Iproceedings</span> <span class="articles-number" data-v-575455fb>510 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://aging.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Aging</span> <span class="articles-number" data-v-575455fb>471 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://www.i-jmr.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>Interactive Journal of Medical Research</span> <span class="articles-number" data-v-575455fb>460 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://xmed.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIRx Med</span> <span class="articles-number" data-v-575455fb>456 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://pediatrics.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Pediatrics and Parenting</span> <span class="articles-number" data-v-575455fb>439 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://cancer.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Cancer</span> <span class="articles-number" data-v-575455fb>420 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://derma.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Dermatology</span> <span class="articles-number" data-v-575455fb>319 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://diabetes.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Diabetes</span> <span class="articles-number" data-v-575455fb>276 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://rehab.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Rehabilitation and Assistive Technologies</span> <span class="articles-number" data-v-575455fb>274 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://cardio.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Cardio</span> <span class="articles-number" data-v-575455fb>211 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://infodemiology.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Infodemiology</span> <span class="articles-number" data-v-575455fb>165 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://ai.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR AI</span> <span class="articles-number" data-v-575455fb>129 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://periop.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Perioperative Medicine</span> <span class="articles-number" data-v-575455fb>124 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://nursing.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Nursing</span> <span class="articles-number" data-v-575455fb>120 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://jopm.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>Journal of Participatory Medicine</span> <span class="articles-number" data-v-575455fb>106 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://biomedeng.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Biomedical Engineering</span> <span class="articles-number" data-v-575455fb>95 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://bioinform.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Bioinformatics and Biotechnology</span> <span class="articles-number" data-v-575455fb>52 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://apinj.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>Asian/Pacific Island Nursing Journal</span> <span class="articles-number" data-v-575455fb>31 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://neuro.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Neurotechnology</span> <span class="articles-number" data-v-575455fb>27 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://www.medicine20.com" no-prefetch="" data-v-575455fb><span data-v-575455fb>Medicine 2.0</span> <span class="articles-number" data-v-575455fb>26 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://xr.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR XR and Spatial Computing (JMXR)</span> <span class="articles-number" data-v-575455fb>24 articles </span></a></li><li class="m-0" data-v-575455fb><a href="/" aria-current="page" class="nuxt-link-exact-active nuxt-link-active" data-v-575455fb><span data-v-575455fb>JMIRx Bio</span> <span class="articles-number" data-v-575455fb>22 articles </span></a></li><li class="m-0" data-v-575455fb><a href="https://data.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Data</span> </a></li><li class="m-0" data-v-575455fb><a href="https://challenges.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Challenges</span> </a></li><li class="m-0" data-v-575455fb><a href="https://preprints.jmir.org" no-prefetch="" data-v-575455fb><span data-v-575455fb>JMIR Preprints</span> </a></li></ul></li></ul></div></section> </nav></div></nav></section></header></div> <div class="container-fluid" style="padding: 0px;"><div id="main-content" class="element-wrapper" data-v-88946f80><section class="journal__info-wrapper" data-v-88946f80><div class="container journal__info" data-v-88946f80><div class="row"><div class="col-12"><div class="journal__info-top"><h1 tabindex="0" aria-label="JMIRx Bio journal" class="journal__info-h1"> JMIRx Bio </h1> <h4><p>An overlay journal for BioRxiv preprints with post-review manuscript marketplace (<a href="https://support.jmir.org/hc/en-us/articles/360034752692">What is JMIRx?</a>).</p></h4> <p class="d-inline-block journal__info-p"><span> Editor-in-Chief: </span> <span><strong class="editor-in-chief"><p><span>Amy Schwartz, MSc, Ph.D., Scientific Editor at JMIR Publications, Ontario, Canada</span></p></strong></span> <br>  </p> <div class="journal__info-decription hide-description"><span><p dir="ltr">JMIRx Bio is an innovative overlay journal to <a href="https://www.biorxiv.org/">BioRxiv</a> and <a href="https://preprints.jmir.org/">JMIR Preprints</a> (other preprint servers are invited to join). JMIRx peer-reviews preprints and publishes their revised "version of record" with peer-review reports across a broad range of biological sciences. We also accept existing reviews from Plan P accredited peer-review services such as PeerRef or PREreview Preprint Journal Clubs.</p> <p dir="ltr">Unlike the majority of JMIR journals, papers published in this journal do not require a digital health focus. We publish all research that qualifies for preprinting on <a href="https://www.biorxiv.org/">BioRxiv</a>. </p> <p dir="ltr">Conceived to address the urgent need to make highly relevant scientific information available as early as possible without losing the quality of the peer-reviewed process, this innovative new journal is the first in a new series of “<a href="https://www.jmir.org/2019/12/e17578#The-Future-of-Publishing-Our-Innovations-for-2020-and-the-Next-20-Years" rel="noopener" target="_blank">superjournals</a>”. Superjournals (a type of <a href="https://en.wikipedia.org/wiki/Overlay_journal">"overlay" journal</a>) sit on top of preprint servers (JMIRx Bio serves <a href="https://www.biorxiv.org/">BioRxiv</a> and <a href="https://preprints.jmir.org">JMIR Preprints</a>), offering peer-review and everything else a traditional scholarly journal does. Our goal is to rapidly peer review and publish a paper. All JMIRx Bio papers must have originated as a preprint. </p> <p dir="ltr">All preprints accepted for curation in JMIRx Bio as "Version-of-Record" are rigorously peer-reviewed, copyedited and XML-tagged. Accepted papers are published along with the related Peer Review Reports and Author Responses to Peer Review Reports, providing an additional layer of transparency to the scholarly publishing process. </p> <p dir="ltr">There is <strong>no Article Processing Fee</strong> directly paid by authors for this journal. JMIRx Bio is a <strong>diamond open access journal</strong> publishing under a <a href="https://support.jmir.org/hc/en-us/articles/360034752692-What-is-JMIRx" target="_blank">PRC</a> model and <a href="https://planp.science/" target="_blank">Plan-P</a> compliant journal, which enables Plan P member universities/institutions and funders to support peer review of preprints and publishing in JMIRx Bio or partner journals. Under Plan P, the institution contributes $1000 towards peer-review (and publication of the peer-review reports), and the funder (if applicable) contributes $1000 for the publication/curation costs, in case the article is accepted. Individual PI-led labs, departments and universities can become institutional members, guaranteeing unlimited peer-review of preprints.</p> <p dir="ltr"><strong>Introductory waivers.</strong> For a limited time only, authors who opt-in during submission to receive PREreview community peer review for their preprint or refer us to their department head/librarian/funder contact will receive a membership-waiver and may publish the preprint in JMIRx Bio at no cost to the author. To benefit from this simply refer us to your library, referral form <a href="https://share.hsforms.com/161SLHEUIR0iwKGluKeGF9wbpk19" target="_blank">provided here</a>.</p> <p dir="ltr">To "submit" (nominate a preprint for JMIRx), please use this form at <a href="https://bio.jmirx.org/landing">https://bio.jmirx.org/landing</a>.</p> <p dir="ltr"><strong>For detailed instructions and other submission options see <a href="https://support.jmir.org/hc/en-us/articles/8877105828635-How-to-submit-to-a-JMIRx-journal"><span>How to submit to a JMIRx journal</span></a></strong></p></span></div> <button class="btn btn-medium btn-blue mt-3" style="margin-bottom: 30px;"><span>Read </span> <span>More</span></button></div></div></div></div>   </section> <main data-v-88946f80><div data-v-30c6e183 data-v-88946f80><section class="articles-wrapper" data-v-30c6e183><h2 id="recent-articles" tabindex="0" aria-label="Recent Articles" class="text-center" data-v-30c6e183> Recent Articles </h2> <div 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#xSystems Biology" class="link card-theme" data-v-30c6e183> #xSystems Biology </a> <div class="card-title" style="flex-grow: 1;" data-v-30c6e183><a href="/2024/1/e43662" data-test="card-title" aria-label="In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study" title="In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study" class="h5" data-v-30c6e183> In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study </a></div> <div class="card-info mt-20 mb-20" data-v-30c6e183><p class="card-info-text" data-v-30c6e183><span data-v-30c6e183>People with type 1 diabetes (T1D) depend on external insulin to regulate their blood glucose level (BGL) within the normoglycemic range between 4.0 to 7.0 mmol/L. Patients with T1D routinely conduct self-monitoring of blood glucose through finger pricks before insulin injections. An artificial pancreas is an innovative device that mimics the function of a healthy pancreas. Despite its recent advancement, the control algorithms used in an artificial pancreas are still lagging in delivering the proper insulin dosage to patients with T1D. Previous researchers attempted to improve the interrelation between parameters and variables in the original Hovorka equations model, later known as the improved Hovorka equations model; however, the improved equations model has not been tested in terms of its usability to regulate and control the BGL in a safe range for 2 or more people with T1D.</span></p> <div class="read-more" data-v-30c6e183><a href="/2024/1/e43662" aria-label="Continue reading this article" class="continue-reading" data-v-30c6e183><span aria-hidden="true" class="icon fas fa-long-arrow-alt-right" data-v-30c6e183></span></a></div></div></div> <div class="card-date-social mt-6 pb-10" data-v-30c6e183><time datetime="2024-08-15" class="mb-0" style="margin-top: 2px;" data-v-30c6e183>2024-08-15 </time> <span class="mx-1" style="margin-top: 2px;" data-v-30c6e183>|</span> <span class="sm-icons" data-v-30c6e183><a title="share-on-Bluesky" 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data-v-30c6e183>The culture of immortal cell lines has become an indispensable tool in the field of modern biotechnology and has been used in the production of human and viral veterinary vaccines, therapeutic recombinant proteins, interferons, and monoclonal antibodies. Several approaches are used to immortalize cells in culture, such as transduction of cells with viral oncogenes, induced expression of telomerase reverse transcriptase, and spontaneous immortalization by serial passage of primary cell lines.</span></p> <div class="read-more" data-v-30c6e183><a href="/2024/1/e53721" aria-label="Continue reading this article" class="continue-reading" data-v-30c6e183><span aria-hidden="true" class="icon fas fa-long-arrow-alt-right" data-v-30c6e183></span></a></div></div></div> <div class="card-date-social mt-6 pb-10" data-v-30c6e183><time datetime="2024-07-18" class="mb-0" style="margin-top: 2px;" data-v-30c6e183>2024-07-18 </time> <span class="mx-1" style="margin-top: 2px;" data-v-30c6e183>|</span> <span class="sm-icons" data-v-30c6e183><a title="share-on-Bluesky" href="https://bsky.app/intent/compose?text=Check%20out%20this%20fascinating%20article%20by%20%40jmirpub.bsky.social!%20https%3A%2F%2Fxbio.jmir.org%2F2024%2F1%2Fe53721" aria-label="Share this 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</div></div></div><script>window.__NUXT__=(function(a,b,c,d,e,f,g,h,i,j,k,l,m,n,o,p,q,r,s,t,u,v,w,x,y,z,A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,_,$,aa,ab,ac,ad,ae,af,ag,ah,ai,aj,ak,al,am,an,ao,ap,aq,ar,as,at,au,av,aw,ax,ay,az,aA,aB,aC,aD,aE,aF,aG,aH,aI,aJ,aK,aL,aM,aN,aO,aP,aQ,aR,aS,aT,aU,aV,aW,aX,aY,aZ,a_,a$,ba,bb,bc,bd,be,bf,bg,bh){return {layout:"front",data:[{carouselItems:[{tabTitle:"Testimonials",slideTitle:"\"Very professional and prompt responses. I was impressed with the interface for submission and the turnaround on submissions and revisions.\"",articleTitle:"Review on SciRev",description:"https:\u002F\u002Fscirev.org\u002Freviews\u002Fjournal-of-medical-internet-research\u002F",image:"\u002F_nuxt\u002Fimg\u002Fplaceholder-testimonial.8ffb428.jpg",backgroundColor:aa,buttons:[{url:{internal:ab,link:"https:\u002F\u002Fdocs.google.com\u002Fforms\u002Fd\u002Fe\u002F1FAIpQLSeG5fmIO98nI54IeywAdGglYqLp67cQBmMwgqt3Qbz_BAp6zQ\u002Fviewform?formkey=dGR6eVMxTEdxblVycV8tMVRmdjRHS2c6MQ"},buttonText:a}]},{tabTitle:"Featured JMIR Sister Journal",slideTitle:ac,description:"Background: The success of big data initiatives depends on public support. Public involvement and engagement could be a way of establishing public support for big data research. Objective: This review aims to synthesize the evidence on public involvement and engagement in big data research. Methods: This scoping review mapped the current evidence on public involvement and engagement activities in big data research. We searched 5 electronic databases, followed by additional manual searches of Google Scholar and gray literature. In total, 2 public contributors were involved at all stages of the review. Results: A total of 53 papers were included in the scoping review. The review showed the ways in which the public could be involved and engaged in big data research. The papers discussed a broad range of involvement activities, who could be involved or engaged, and the importance of the context in which public involvement and engagement occur. The findings show how public involvement, engagement, and consultation could be delivered in big data research. Furthermore, the review provides examples of potential outcomes that were produced by involving and engaging the public in big data research. Conclusions: This review provides an overview of the current evidence on public involvement and engagement in big data research. While the evidence is mostly derived from discussion papers, it is still valuable in illustrating how public involvement and engagement in big data research can be implemented and what outcomes they may yield. Further research and evaluation of public involvement and engagement in big data research are needed to better understand how to effectively involve and engage the public in big data research. ",articleTitle:"Public Involvement and Engagement in Big Data Research: Scoping Review",citation:"- Vol 16 Issue 1",image:"https:\u002F\u002Fasset.jmir.pub\u002Fassets\u002Ff9a3a4531cb23a462be9566dbec98d86.png",backgroundColor:"#582365",buttons:[{url:{internal:ab,link:ad},buttonText:"Visit Journal"}]},{tabTitle:"Latest Submission Open for Open-Review",slideTitle:"There are no submissions available for Open-Review at this time.",description:d,image:"\u002F_nuxt\u002Fimg\u002Fplaceholder-research.52b85b8.jpg",backgroundColor:"#a7e394",buttons:[]},{tabTitle:"Latest Announcement",slideTitle:ae,description:d,image:"\u002F_nuxt\u002Fimg\u002Fplaceholder-announcements.41ae07b.jpg",backgroundColor:aa,buttons:[{url:{internal:f,link:"\u002Fannouncements\u002F352"},buttonText:"View Announcement"}]},{tabTitle:"Featured Theme",slideTitle:"#xMolecular Biology",articleTitle:af,description:"\u003Cstrong\u003EBackground:\u003C\u002Fstrong\u003E The culture of immortal cell lines has become an indispensable tool in the field of modern biotechnology and has been used in the production of human and viral veterinary vaccines, therapeutic recombinant proteins, interferons, and monoclonal antibodies. Several approaches are used to immortalize cells in culture, such as transduction of cells with viral oncogenes, induced expression of telomerase reverse transcriptase, and spontaneous immortalization by serial passage of primary cell lines.\n\u003Cstrong\u003EObjective:\u003C\u002Fstrong\u003E This study aimed to establish an immortal cell line by serial passage of fetal ovine heart cells that could be used to produce veterinary viral vaccines.\n\u003Cstrong\u003EMethods:\u003C\u002Fstrong\u003E We serially passaged primary heart cells prepared from a fetal ovine heart till passage 140. We studied the events that led to the transformation and immortalization of the cell line under light and phase contrast microscopy. DNA samples of the cell line at passages 22 (before transformation) and 47 (after transformation) were genotyped according to single nucleotide polymorphisms (SNPs) using the OvineSNP50 BeadChip (Illumina). We sequenced the \u003Ci\u003Ecytochrome b\u003C\u002Fi\u003E gene, control region, and \u003Ci\u003EtRNA-Phe\u003C\u002Fi\u003E and \u003Ci\u003E12S rRNA\u003C\u002Fi\u003E genes of the mitochondrial genome of the cell line at passages 26 and 59 by Sanger sequencing. The susceptibility of the cell line to sheep pox, Peste des petits ruminants (PPR), lumpy skin disease (LSD), Rift Valley fever (RVF), and camel pox viruses was investigated.\n\u003Cstrong\u003EResults:\u003C\u002Fstrong\u003E We established a unique immortal cell line called fetal ovine heart–Saudi Arabia (FOH-SA) by serial passage of fetal ovine heart cells. We demonstrated that the transformation or immortalization of the cell line resulted from spontaneous cellular and nuclear fusion of 2 morphologically distinct cardiocytes at passage 29. Fused cells at passage 29 gave rise to progeny cells, which grew into multicellular filaments that persisted at passages 30, 31, and 32. Trypsinization of the filamentous multicellular growth at passage 32 gave an epithelial-type immortal heart cell line. SNP genotyping revealed 65% and 96% homozygosity in SNP genotypes of the cell line at passages 22 and 47, respectively. Partial sequencing of the mitochondrial genome of the cell line revealed mutational events in the control region and the \u003Ci\u003EtRNA-Phe\u003C\u002Fi\u003E and \u003Ci\u003E12S rRNA\u003C\u002Fi\u003E genes of the mitochondrial genome of passage 59 cells. The cell line was found to be permissive to sheep pox, PPR, LSD, RVF, and camel pox viruses.\n\u003Cstrong\u003EConclusions:\u003C\u002Fstrong\u003E We established an immortal cell line by serial passage of primary fetal ovine heart cells, which was permissive to many animal viruses. It could be used in animal virus isolation, vaccine production, and biotechnology. The study reported spontaneous cell fusion of cardiocytes as a method of cell immortalization. The findings of this study might help address the mystery of how the VERO cell line evolved.\n",image:ag,backgroundColor:"#295620",buttons:[{url:{internal:f,link:ah},buttonText:"Read Article"},{url:{internal:f,link:"\u002Fthemes\u002F1393"},buttonText:"View Theme"},{url:{internal:f,link:"\u002Fthemes"},buttonText:"View All Themes"}]}]}],fetch:{},error:a,state:{host:a,environment:c,journalPath:i,keys:{},domains:{},screensize:"desktop",defaultCookieScriptId:"aa022ba6-b337-11ef-b288-3fb59f57942d",accessibility:{filter:"none","font-weight":"inherit","font-size":.625,"text-align":"initial"},announcements:{data:[{announcement_id:352,title:ae,description_short:"\u003Cp\u003EJMIR Publications and PREreview are pleased to announce our next Live Preprint Journal Club on September 16th, 2022 at 12pm EST. We are bringing together scientists from across the globe for a virtual discussion and collaborative review of a recent \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002Fcontent\u002F10.1101\u002F2022.07.22.501121v1\" target=\""_blank"\"\u003Epreprint\u003C\u002Fa\u003E covering an assessment of Nano-RECall: Interpretation of Oxford Nanopore sequence data for HIV-1 drug resistance testing.\u003C\u002Fp\u003E",date_posted:"2022-09-09T09:44:19.000Z",journal_id:u}],pagination:{from:b,to:o,total:b,perPage:o,firstPage:b,lastPage:b}},article:{data:{thumbnail:g,title:d,abstract:{Background:d,Objective:d,Methods:d,Result:d,Conculsion:d},primaryAuthor:a}},articles:{recent:[{thumbnail:g,title:"Authors' Response to Peer Review of “Exploring the Accuracy of Ab Initio Prediction Methods for Viral Pseudoknotted RNA Structures (Preprint)”",article_id:67586,url:"\u002F2024\u002F1\u002Fe67586",published_at:"2024-11-05T15:00:24.000Z",doi:"10.2196\u002F67586",preview:h,section:{title:v,section_id:w}},{thumbnail:"https:\u002F\u002Fasset.jmir.pub\u002Fassets\u002Fc20a8ce242395e55307cc8b3086958b8.png",title:"Exploring the Accuracy of Ab Initio Prediction Methods for Viral Pseudoknotted RNA Structures: Retrospective Cohort Study",article_id:58899,url:"\u002F2024\u002F1\u002Fe58899",published_at:"2024-11-05T15:00:06.000Z",doi:"10.2196\u002F58899",preview:"The prediction of tertiary RNA structures is significant to the field of medicine (eg, messenger RNA [mRNA] vaccines, genome editing) and the exploration of viral transcripts. Though many RNA folding software programs exist, few studies have condensed their locus of attention solely to viral pseudoknotted RNA. These regulatory pseudoknots play a role in genome replication, gene expression, and protein synthesis.",section:{title:"#PREreview Live Review",section_id:1246}},{thumbnail:g,title:"Peer Review of “Exploring the Accuracy of Ab Initio Prediction Methods for Viral Pseudoknotted RNA Structures (Preprint)”",article_id:65154,url:"\u002F2024\u002F1\u002Fe65154",published_at:"2024-09-11T14:31:13.000Z",doi:"10.2196\u002F65154",preview:h,section:{title:"#PREreview Live Review Report",section_id:1590}},{thumbnail:g,title:"Authors’ Response to Peer Reviews of “In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study”",article_id:64442,url:"\u002F2024\u002F1\u002Fe64442",published_at:"2024-08-15T13:30:40.000Z",doi:"10.2196\u002F64442",preview:h,section:{title:v,section_id:w}},{thumbnail:g,title:ai,article_id:64403,url:"\u002F2024\u002F1\u002Fe64403",published_at:"2024-08-15T13:30:29.000Z",doi:"10.2196\u002F64403",preview:h,section:{title:j,section_id:k}},{thumbnail:g,title:ai,article_id:63851,url:"\u002F2024\u002F1\u002Fe63851",published_at:"2024-08-15T13:30:22.000Z",doi:"10.2196\u002F63851",preview:h,section:{title:j,section_id:k}},{thumbnail:"https:\u002F\u002Fasset.jmir.pub\u002Fassets\u002F311788996985b853094f4cd4e3c50779.png",title:"In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study",article_id:43662,url:"\u002F2024\u002F1\u002Fe43662",published_at:"2024-08-15T13:30:04.000Z",doi:"10.2196\u002F43662",preview:"People with type 1 diabetes (T1D) depend on external insulin to regulate their blood glucose level (BGL) within the normoglycemic range between 4.0 to 7.0 mmol\u002FL. Patients with T1D routinely conduct self-monitoring of blood glucose through finger pricks before insulin injections. An artificial pancreas is an innovative device that mimics the function of a healthy pancreas. Despite its recent advancement, the control algorithms used in an artificial pancreas are still lagging in delivering the proper insulin dosage to patients with T1D. Previous researchers attempted to improve the interrelation between parameters and variables in the original Hovorka equations model, later known as the improved Hovorka equations model; however, the improved equations model has not been tested in terms of its usability to regulate and control the BGL in a safe range for 2 or more people with T1D.",section:{title:"#xSystems Biology",section_id:1402}},{thumbnail:g,title:aj,article_id:63336,url:"\u002F2024\u002F1\u002Fe63336",published_at:"2024-07-18T12:16:28.000Z",doi:"10.2196\u002F63336",preview:h,section:{title:j,section_id:k}},{thumbnail:g,title:"Authors’ Response to Peer Reviews of “Establishment of a Novel Fetal Ovine Heart Cell Line by Spontaneous Cell Fusion: Experimental Study”",article_id:62911,url:"\u002F2024\u002F1\u002Fe62911",published_at:"2024-07-18T12:16:17.000Z",doi:"10.2196\u002F62911",preview:h,section:{title:v,section_id:w}},{thumbnail:g,title:aj,article_id:62905,url:"\u002F2024\u002F1\u002Fe62905",published_at:"2024-07-18T12:16:07.000Z",doi:"10.2196\u002F62905",preview:h,section:{title:j,section_id:k}},{thumbnail:ag,title:af,article_id:53721,url:ah,published_at:"2024-07-18T12:15:04.000Z",doi:"10.2196\u002F53721",preview:"The culture of immortal cell lines has become an indispensable tool in the field of modern biotechnology and has been used in the production of human and viral veterinary vaccines, therapeutic recombinant proteins, interferons, and monoclonal antibodies. Several approaches are used to immortalize cells in culture, such as transduction of cells with viral oncogenes, induced expression of telomerase reverse transcriptase, and spontaneous immortalization by serial passage of primary cell lines.",section:{title:"#xCell Biology",section_id:1383}},{thumbnail:g,title:"Peer Review of “Roles of Progranulin and FRamides in Neural Versus Nonneural Tissues on Dietary Restriction–Related Longevity and Proteostasis in C. elegans (Preprint)”",article_id:60571,url:"\u002F2024\u002F1\u002Fe60571",published_at:"2024-06-17T11:45:14.000Z",doi:"10.2196\u002F60571",preview:h,section:{title:j,section_id:k}}],openReview:[]},articleTypes:{},authentication:{data:a,jwt:a},countries:{data:[]},departments:{data:[]},help:{data:{}},journal:{data:{journal_id:u,title:x,tag:y,description:d,path:i,slug:i,seq:z,enabled:b,environment:c,url:ak,batch:e,year:al,colour:am,impact:a,order:p,published:l,transfers:a,cite_score:a,settings:{aboutJournal:"\u003Cp dir=\"ltr\"\u003EJMIRx Bio is an innovative overlay journal to \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002F\"\u003EBioRxiv\u003C\u002Fa\u003E and \u003Ca href=\"https:\u002F\u002Fpreprints.jmir.org\u002F\"\u003EJMIR Preprints\u003C\u002Fa\u003E (other preprint servers are invited to join). JMIRx peer-reviews preprints and publishes their revised \"version of record\" with peer-review reports across a broad range of biological sciences. We also accept existing reviews from Plan P accredited peer-review services such as PeerRef or PREreview Preprint Journal Clubs.\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003EUnlike the majority of JMIR journals, papers published in this journal do not require a digital health focus. We publish all research that qualifies for preprinting on \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002F\"\u003EBioRxiv\u003C\u002Fa\u003E. \u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003EConceived to address the urgent need to make highly relevant scientific information available as early as possible without losing the quality of the peer-reviewed process, this innovative new journal is the first in a new series of “\u003Ca href=\"https:\u002F\u002Fwww.jmir.org\u002F2019\u002F12\u002Fe17578#The-Future-of-Publishing-Our-Innovations-for-2020-and-the-Next-20-Years\" rel=\"noopener\" target=\"_blank\"\u003Esuperjournals\u003C\u002Fa\u003E”. Superjournals (a type of \u003Ca href=\"https:\u002F\u002Fen.wikipedia.org\u002Fwiki\u002FOverlay_journal\"\u003E\"overlay\" journal\u003C\u002Fa\u003E) sit on top of preprint servers (JMIRx Bio serves \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002F\"\u003EBioRxiv\u003C\u002Fa\u003E and \u003Ca href=\"https:\u002F\u002Fpreprints.jmir.org\"\u003EJMIR Preprints\u003C\u002Fa\u003E), offering peer-review and everything else a traditional scholarly journal does. Our goal is to rapidly peer review and publish a paper. All JMIRx Bio papers must have originated as a preprint. \u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003EAll preprints accepted for curation in JMIRx Bio as \"Version-of-Record\" are rigorously peer-reviewed, copyedited and XML-tagged. Accepted papers are published along with the related Peer Review Reports and Author Responses to Peer Review Reports, providing an additional layer of transparency to the scholarly publishing process. \u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003EThere is \u003Cstrong\u003Eno Article Processing Fee\u003C\u002Fstrong\u003E directly paid by authors for this journal. JMIRx Bio is a \u003Cstrong\u003Ediamond open access journal\u003C\u002Fstrong\u003E publishing under a \u003Ca href=\"https:\u002F\u002Fsupport.jmir.org\u002Fhc\u002Fen-us\u002Farticles\u002F360034752692-What-is-JMIRx\" target=\"_blank\"\u003EPRC\u003C\u002Fa\u003E model and \u003Ca href=\"https:\u002F\u002Fplanp.science\u002F\" target=\"_blank\"\u003EPlan-P\u003C\u002Fa\u003E compliant journal, which enables Plan P member universities\u002Finstitutions and funders to support peer review of preprints and publishing in JMIRx Bio or partner journals. Under Plan P, the institution contributes $1000 towards peer-review (and publication of the peer-review reports), and the funder (if applicable) contributes $1000 for the publication\u002Fcuration costs, in case the article is accepted. Individual PI-led labs, departments and universities can become institutional members, guaranteeing unlimited peer-review of preprints.\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cstrong\u003EIntroductory waivers.\u003C\u002Fstrong\u003E For a limited time only, authors who opt-in during submission to receive PREreview community peer review for their preprint or refer us to their department head\u002Flibrarian\u002Ffunder contact will receive a membership-waiver and may publish the preprint in JMIRx Bio at no cost to the author. To benefit from this simply refer us to your library, referral form \u003Ca href=\"https:\u002F\u002Fshare.hsforms.com\u002F161SLHEUIR0iwKGluKeGF9wbpk19\" target=\"_blank\"\u003Eprovided here\u003C\u002Fa\u003E.\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003ETo \"submit\" (nominate a preprint for JMIRx), please use this form at \u003Ca href=\"https:\u002F\u002Fbio.jmirx.org\u002Flanding\"\u003Ehttps:\u002F\u002Fbio.jmirx.org\u002Flanding\u003C\u002Fa\u003E.\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cstrong\u003EFor detailed instructions and other submission options see \u003Ca href=\"https:\u002F\u002Fsupport.jmir.org\u002Fhc\u002Fen-us\u002Farticles\u002F8877105828635-How-to-submit-to-a-JMIRx-journal\"\u003E\u003Cspan\u003EHow to submit to a JMIRx journal\u003C\u002Fspan\u003E\u003C\u002Fa\u003E\u003C\u002Fstrong\u003E\u003C\u002Fp\u003E",announcementLink:d,copyrightNotice:"This is an open-access article distributed under the terms of the Creative Commons Attribution License (https:\u002F\u002Fcreativecommons.org\u002Flicenses\u002Fby\u002F4.0\u002F), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIRx Bio, is properly cited. The complete bibliographic information, a link to the original publication on https:\u002F\u002Fbio.jmirx.org\u002F, as well as this copyright and license information must be included.",focusScopeDesc:"\u003Cp dir=\"ltr\"\u003E\u003Cspan\u003EJMIRx Bio is an innovative overlay journal to \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002F\"\u003EBioRxiv\u003C\u002Fa\u003E and \u003Ca href=\"https:\u002F\u002Fpreprints.jmir.org\u002F\"\u003EJMIR Preprints\u003C\u002Fa\u003E (other preprint servers are invited to join). JMIRx peer-reviews preprints and publishes their revised \"version of record\" with peer-review reports across a broad range of biological sciences. Unlike the majority of JMIR journals, papers published in this journal do not require a digital health focus. We publish all research that qualifies for preprinting on \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002F\"\u003EBioRxiv\u003C\u002Fa\u003E. \u003C\u002Fspan\u003E\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cspan\u003EConceived to address \u003C\u002Fspan\u003E\u003Cspan\u003Ethe urgent need to make highly relevant scientific information available as early as possible without losing the quality of the peer-reviewed process, this\u003C\u002Fspan\u003E\u003Cspan\u003E innovative new journal is the first in a new series of “\u003Ca href=\"https:\u002F\u002Fwww.jmir.org\u002F2019\u002F12\u002Fe17578#The-Future-of-Publishing-Our-Innovations-for-2020-and-the-Next-20-Years\" target=\"_blank\" rel=\"noopener\"\u003Esuperjournals\u003C\u002Fa\u003E”. Superjournals (a type of \u003C\u002Fspan\u003E\u003Ca href=\"https:\u002F\u002Fen.wikipedia.org\u002Fwiki\u002FOverlay_journal\"\u003E\u003Cspan\u003E\"overlay\" journal\u003C\u002Fspan\u003E\u003C\u002Fa\u003E\u003Cspan\u003E) sit on top of preprint servers (JMIRx Bio serves \u003Ca href=\"https:\u002F\u002Fwww.biorxiv.org\u002F\"\u003EBioRxiv\u003C\u002Fa\u003E and \u003Ca href=\"https:\u002F\u002Fpreprints.jmir.org\"\u003EJMIR Preprints\u003C\u002Fa\u003E), offering peer-review and everything else a traditional scholarly journal does. Our goal is to rapidly peer review and publish a paper. All JMIRx Bio papers must have originated as a preprint. \u003C\u002Fspan\u003E\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cspan\u003EAll preprints accepted for curation in JMIRx Bio as \"Version-of-Record\" are rigorously peer-reviewed, copyedited and XML-tagged. Accepted papers are published along with the related Peer Review Reports and Author Responses to Peer Review Reports, providing an additional layer of transparency to the scholarly publishing process. \u003C\u002Fspan\u003E\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cspan\u003EThere is no Article Processing Fee for this journal. We are selling institutional memberships to funders, libraries and library consortia under the name \u003Cstrong\u003E\u003Ca href=\"https:\u002F\u002Fplanp.science\u002F\"\u003EPlan P\u003C\u002Fa\u003E (Subscribe to Peer Review \u002F Transform to Open Science)\u003C\u002Fstrong\u003E. Individual or Department\u002FLab-based memberships will be available. \u003C\u002Fspan\u003E\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cspan\u003ETo \"submit\" (nominate a preprint for JMIRx), please use this form at \u003Ca href=\"https:\u002F\u002Fbio.jmirx.org\u002Flanding\"\u003Ehttps:\u002F\u002Fbio.jmirx.org\u002Flanding\u003C\u002Fa\u003E.\u003C\u002Fspan\u003E\u003C\u002Fp\u003E\r\n\u003Cp dir=\"ltr\"\u003E\u003Cspan\u003E \u003Cstrong\u003EFor detailed instructions and other submission options see \u003Ca href=\"https:\u002F\u002Fsupport.jmir.org\u002Fhc\u002Fen-us\u002Farticles\u002F8877105828635-How-to-submit-to-a-JMIRx-journal\"\u003E\u003Cspan xmlns=\"http:\u002F\u002Fwww.w3.org\u002F1999\u002Fxhtml\" style=\"color: #0072ef;\"\u003EHow to submit to a JMIRx journal\u003C\u002Fspan\u003E\u003C\u002Fa\u003E\u003C\u002Fstrong\u003E\u003C\u002Fspan\u003E\u003Ca href=\"https:\u002F\u002Fsupport.jmir.org\u002Fhc\u002Fen-us\u002Farticles\u002F360034752692-What-is-JMIRx-\"\u003E\u003Cspan\u003E\u003C\u002Fspan\u003E\u003C\u002Fa\u003E\u003C\u002Fp\u003E",googleAnalyticsId:d,impactFactor:d,journalDescription:"\u003Cp\u003EAn overlay journal for BioRxiv preprints with post-review manuscript marketplace (\u003Ca href=\"https:\u002F\u002Fsupport.jmir.org\u002Fhc\u002Fen-us\u002Farticles\u002F360034752692\"\u003EWhat is JMIRx?\u003C\u002Fa\u003E).\u003C\u002Fp\u003E",journalInitials:"JMIRxBio",footer:"\u003Cdiv\u003E\r\n\u003Cul style=\"display: flex; flex-wrap: wrap; list-style: none; justify-content: center;\"\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003Ca href=\"https:\u002F\u002Fpublicationethics.org\u002Fmembers\u002Fjournal-medical-internet-research-jmir\" target=\"_blank\" rel=\"noopener\"\u003E\u003C\u002Fa\u003E\u003C\u002Fli\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003Cimg src=\"https:\u002F\u002Fasset.jmir.pub\u002Fresources\u002Fimages\u002Fpartners\u002Fopen-access.jpg\" alt=\"Open Access\" \u002F\u003E\u003C\u002Fli\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003Ca href=\"https:\u002F\u002Foaspa.org\u002Fmember-record-jmir-publications-inc\" target=\"_blank\" rel=\"noopener\"\u003E\u003Cimg src=\"https:\u002F\u002Fasset.jmir.pub\u002Fresources\u002Fimages\u002Fpartners\u002Foaspa.jpg\" alt=\"Open Access Scholarly Publishers Association\" \u002F\u003E\u003C\u002Fa\u003E\u003C\u002Fli\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003Ca href=\"https:\u002F\u002Fwww.stm-assoc.org\" target=\"_blank\" rel=\"noopener\"\u003E\u003Cimg src=\"https:\u002F\u002Fasset.jmir.pub\u002Fresources\u002Fimages\u002Fpartners\u002Fstm.jpg\" alt=\"STM Member\" \u002F\u003E\u003C\u002Fa\u003E\u003C\u002Fli\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003Ca href=\"https:\u002F\u002Fwww.trendmd.com\" target=\"_blank\" rel=\"noopener\"\u003E\u003Cimg src=\"https:\u002F\u002Fasset.jmir.pub\u002Fresources\u002Fimages\u002Fpartners\u002Ftrend-MD.jpg\" alt=\"TrendMD Member\" \u002F\u003E\u003C\u002Fa\u003E\u003C\u002Fli\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003C\u002Fli\u003E\r\n\u003Cli style=\"margin: 10px;\"\u003E\u003Ca href=\"https:\u002F\u002Forcid.org\" target=\"_blank\" rel=\"noopener\"\u003E\u003Cimg src=\"https:\u002F\u002Fasset.jmir.pub\u002Fresources\u002Fimages\u002Fpartners\u002FORCID.jpg\" alt=\"ORCID Member\" \u002F\u003E\u003C\u002Fa\u003E\u003C\u002Fli\u003E\r\n\u003C\u002Ful\u003E\r\n\u003C\u002Fdiv\u003E",journalPartnerships:["cope","open-access","oaspa","stm","trend-md","orcid"],onlineIssn:d,searchDescription:x,searchKeywords:"Medical, Medicine, Internet, Research, Journal, ehealth, JMIR, open access publishing, medical research, medical informatics",submitButton:{enabled:f,label:"Submit Article"},partnershipsWidget:{enabled:f},searchWidget:{enabled:f},openReviewWidget:{enabled:f,count:q,label:"\u003Ca href=\"https:\u002F\u002Fpreprints.jmir.org\"\u003EPreprints\u003C\u002Fa\u003E Open for Peer-Review"},articlesWidget:{enabled:f,count:q,label:"Recent Articles"},submissionChecklist:[{order:"1",content:"\u003Cp\u003EThe submission has not been previously published nor is it before another journal for consideration; or an explanation has been provided in Comments to the Editor. Related\u002Foverlapping published or submitted work will be uploaded as supplementary files so reviewers and editors can determine the degree of overlap with previous\u002Fother papers under consideration. Salami slicing of research is discouraged.\u003C\u002Fp\u003E"},{order:"2",content:"\u003Cp\u003EThe submission file is in Microsoft Word (.doc\u002F.docx) file format.\u003C\u002Fp\u003E"},{order:"3",content:"\u003Cp\u003EThe text meets this journal's formatting requirements, in particular those summarized in the \u003Ca href=\"http:\u002F\u002Fwww.jmir.org?Instructions_for_Authors:Instructions_for_Authors_of_JMIR#checklist\" target=\"_blank\"\u003EAuthor Checklist\u003C\u002Fa\u003E found in Instructions for Authors. The text employs \u003Cem\u003Eitalics\u003C\u002Fem\u003E, rather than \u003Cspan style=\"text-decoration: underline;\"\u003Eunderlining\u003C\u002Fspan\u003E or bold as emphasis; with figures and tables (portrait only, no landscape format) placed within the text, rather than at the end. Additional information has been put in separate files to be uploaded as Multimedia Appendix.\u003C\u002Fp\u003E"},{order:an,content:"\u003Cp\u003EI have read and understood the \u003Ca href=\"..\u002F..\u002F\u002F?Instructions_for_Authors:Instructions_for_Authors_of_JMIR#Open_Access\" target=\"_blank\"\u003Efee schedule\u003C\u002Fa\u003E. In particular, I understand and agree that unless my department\u002Forganization is a \u003Ca href=\"..\u002F..\u002Fsupport.htm\" target=\"_blank\"\u003Einstitutional member\u003C\u002Fa\u003E BEFORE submission (see dropdown-list in step 1 of the submission process), I\u002Fmy department will be billed for the article processing fee (see Instructions for authors) in case of acceptance. PLEASE MENTION IN THE COVER LETTER ON SUBMISSION THAT YOU 1) AGREE TO PAY THE APF, OR 2) IF YOU THINK THAT THE APF SHOULD BE WAIVED DUE TO MEMBERSHIP OR FOR ANY OTHER REASONS. Journal sections marked with * may be eligible for a fee waiver or reduction under certain circumstances (must be justified in the comments field for the editor on submission). APFs may not apply for article categories marked with * (check instructions for authors). ** Special fees (in particular a submission fee) apply for \u003Ca href=\"..\u002F..\u002F\u002F?Instructions_for_Authors:Protocol_review\" target=\"_blank\"\u003Eresearch protocols and grant proposals\u003C\u002Fa\u003E. Note that the APF will also be billed if the author retracts the manuscript after acceptance, or if a case of scientific misconduct prevents us from publishing a manuscript after acceptance. \u003C\u002Fp\u003E\r\n\u003Cp\u003EPlease note the price increase for JMIR in July 2015.\u003C\u002Fp\u003E"},{order:"6",content:"\u003Cp\u003EAll cited webreferences (webpages, online available PDF reports) which are NOT journal articles or which do not have a DOI have been cached using WebCite (\u003Ca href=\"http:\u002F\u002Fwww.webcitation.org\" target=\"_blank\"\u003Ewww.webcitation.org\u003C\u002Fa\u003E) . Instead of citing the \"live\" webpage\u002Fwebsite, the author should cite the WebCite archived webpage. No URLs in the body of the manuscript are allowed - all URLs are cited as references.\u003C\u002Fp\u003E"},{order:"8",content:"\u003Cp\u003E(please check this checkbox even if you do not wish to fast-track as an indication that you read this). I understand that if I wish to fast-track the paper, I will pay the Fast-Track-Fee immediately after submission (a payment link will be provided after submission) or at a later stage. The FTF guarantees an editorial decision within 15 working days (see website for further instructions)\u003C\u002Fp\u003E"},{order:"9",content:"\u003Cp\u003EI understand that all author names and their affiliations for the final publication will be taken from the database (metadata form), not the submitted manuscript, thus all author names must be entered in the metadata form during submission. Authors may remove author names from the manuscript if they prefer blind review. All coauthors have been\u002Fwill be entered in the metadata form, and all coauthors fulfill ICMJE criteria in that they made 1) substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data; 2) drafting the article or revising it critically for important intellectual content; and 3) final approval of the version to be published. Authors should meet conditions 1, 2, and 3.\u003C\u002Fp\u003E"},{order:"10",content:"\u003Cp\u003EP-values are reported in accordance with our \u003Ca href=\"..\u002F..\u002F\u002F?Instructions_for_Authors:Instructions_for_Authors_of_JMIR#p\" target=\"_blank\"\u003Einstructions for authors\u003C\u002Fa\u003E.\u003C\u002Fp\u003E"},{order:"11",content:"\u003Cp\u003ESince 26 Oct 2006, we now require payment of a \u003Cstrong\u003EUS$ 90 submission fee\u003C\u002Fstrong\u003E for ALL articles submitted to the \u003Cem\u003EJ Med Internet Res\u003C\u002Fem\u003E (=this journal) EXCEPT letters or invited articles (there is no submission fee for sister journals - please change the journal in the drop down list above before proceeding). You can use Paypal or a credit card immediately after submission. Authors will not be able to complete the submission process without payment. This fee cannot be waived (only exception: invited articles), needs to be paid also by institutional members, and is non-refundable. This fee is in addition to other potential fees such as the optional fast-track fee (FTF) and the article processing fee (APF) for non-members. Authors should understand that the submission fee is non-refundable, even if the manuscript is promptly rejected without peer-review (we do send out the majority of papers for peer-review, but we reserve the right to reject papers without peer-review for any reason, including the topic not being deemed interesting enough, which is a subjective decision by the editor).\u003C\u002Fp\u003E"},{order:"12",content:"\u003Cp\u003EAuthors agree that the manuscript and peer-review reports may be transferred to a JMIR sister\u002Fpartner journal (e.g. \u003Ca href=\"http:\u002F\u002Fwww.i-jmr.org\" target=\"_blank\"\u003Ei-JMR\u003C\u002Fa\u003E, \u003Ca href=\"http:\u002F\u002Fwww.researchprotocols.org\" target=\"_blank\"\u003EJMIR Res Protoc\u003C\u002Fa\u003E, JMIR mHealth, JMIR Human Factors and others), if the paper is not found suitable for publication in JMIR, but is publishable in another journal. The submission fee for that partner journal (if any) will be waived, and transfer of the peer-review reports may mean that the paper does not have to be re-reviewed. Authors will receive a notification when the manuscript is transferred, and at that time can decide if they want to pursue publication in a sister\u002Fpartner journal. If authors do NOT wish an automatic transfer to an alternative journal after rejection for JMIR, this should be noted in the cover letter.\u003C\u002Fp\u003E"}],editorInChief:"\u003Cp\u003E\u003Cspan\u003EAmy Schwartz, MSc, Ph.D., Scientific Editor at JMIR Publications, Ontario, Canada\u003C\u002Fspan\u003E\u003C\u002Fp\u003E"}}},journals:{data:[{journal_id:b,title:"Journal of Medical Internet Research",tag:"The leading peer-reviewed journal for digital medicine and health and health care in the internet age. June 2024 - Journal Impact Factor: 5.8. 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