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renal</title> <meta name="description" content="Search results for: renal"> <meta name="keywords" content="renal"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" 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class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="renal"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 296</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: renal</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">296</span> Simulation Of A Renal Phantom Using the MAG 3</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ati%20Moncef">Ati Moncef</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We describe in this paper the results of a phantom of dynamics renal with MAG3. Our phantom consisted of (tow shaped of kidneys, 1 liver). These phantoms were scanned with static and dynamic protocols and compared with clinical data. in a normal conditions we use our phantoms it's possible to acquire a renal images when we can be compared with clinical scintigraphy. In conclusion, Renal phantom also can use in the quality control of a renal scintigraphy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Renal%20scintigraphy" title="Renal scintigraphy">Renal scintigraphy</a>, <a href="https://publications.waset.org/abstracts/search?q=MAG3" title=" MAG3"> MAG3</a>, <a href="https://publications.waset.org/abstracts/search?q=Nuclear%20medicine" title=" Nuclear medicine"> Nuclear medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=Gamma%20Camera." title=" Gamma Camera."> Gamma Camera.</a> </p> <a href="https://publications.waset.org/abstracts/21031/simulation-of-a-renal-phantom-using-the-mag-3" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21031.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">401</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">295</span> Outcomes of Live Renal Donors with a History of Nephrolithiasis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bin%20Mohamed%20Ebrahim">Bin Mohamed Ebrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Aminesh%20Singla"> Aminesh Singla</a>, <a href="https://publications.waset.org/abstracts/search?q=Henry%20Pleass"> Henry Pleass</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aim: There is an ongoing gap in renal transplantation between organs available for donation and recipients on the waiting list. Live donors with pre-existing or a history of renal calculi were thought to be a relative contraindication due to safety concerns for donors. We aim to review current literature assessing outcomes of donors who were found to have a history of renal calculi. Methods: Ovid and Embase were searched between 1960 to 2021 using key terms and Medical Subject Headings (MeSH) – nephrolithiasis, renal stones, renal transplantation and renal graft. Articles included conference proceedings and journal articles and were not excluded based on patient numbers. Studies were excluded if the specific organ was not identified, duplicated reports found or if post-transplant outcomes were not recorded. Outcomes were donor’s renal function or renal calculi recurrence postoperatively. Results: Upon reviewing 344 articles, 14 manuscripts met inclusion criteria. A total of 152 live donors were identified as having pre-existing or with a history of renal calculi at pre-operative workup. The mean stone size was 2.6 4mm (1 – 16) with a mean follow-up duration of 31.8 months (1 – 96). Seven studies had both outcomes. None showed renal complications or stone recurrence. The remaining studies contained 2 out of 84 patients having recurrent nephrolithiasis. Conclusion: Data suggests minimal morbidity involved for live renal donors with a history of nephrolithiasis. This should encourage surgeons to continue recruiting such donors for kidney transplantation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20transplantation" title="renal transplantation">renal transplantation</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20graft" title=" renal graft"> renal graft</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrolithiasis" title=" nephrolithiasis"> nephrolithiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20calculi" title=" renal calculi"> renal calculi</a>, <a href="https://publications.waset.org/abstracts/search?q=live%20donor" title=" live donor"> live donor</a> </p> <a href="https://publications.waset.org/abstracts/140954/outcomes-of-live-renal-donors-with-a-history-of-nephrolithiasis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140954.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">294</span> Renal Amyloidosis in Domestic Iranian Sheep</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Keivan%20Jamshidi">Keivan Jamshidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Fateme%20Behbahani"> Fateme Behbahani</a>, <a href="https://publications.waset.org/abstracts/search?q=Sara%20Omidi"> Sara Omidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadia%20Shahi"> Nadia Shahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alireza%20Farkhonde"> Alireza Farkhonde</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Amyloidosis represents a heterogenous group of diseases that have in common the deposition of fibrils composed of proteins of beta-pleated sheet structure, which can be specifically identified by histochemistry using the Congo red or similar stains. Between October 2013 to April 2014 (6 months) different patterns of renal amyloidosis was diagnosed on histopathological examination of kidneys belong to 196 out of 7065 slaughtered sheep subjected to postmortem examination. Microscopic examination of renal tissue sections stained with H&E and CR staining techniques revealed 3 patterns of renal amyloid deposition; including glomerular (22.72%), medullary (68.18%), and vascular (9.09%) were recognized. Renal medullary amyloidosis (RMA) was detected as the most prevalence pattern of renal amyloidosis in domestic sheep. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sheep" title="sheep">sheep</a>, <a href="https://publications.waset.org/abstracts/search?q=amyloidosis" title=" amyloidosis"> amyloidosis</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=slaughterhouse" title=" slaughterhouse"> slaughterhouse</a> </p> <a href="https://publications.waset.org/abstracts/79052/renal-amyloidosis-in-domestic-iranian-sheep" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79052.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">375</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">293</span> Development of a Spatial Data for Renal Registry in Nigeria Health Sector</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Adekunle%20Kolawole%20Ojo">Adekunle Kolawole Ojo</a>, <a href="https://publications.waset.org/abstracts/search?q=Idowu%20Peter%20Adebayo"> Idowu Peter Adebayo</a>, <a href="https://publications.waset.org/abstracts/search?q=Egwuche%20Sylvester%20O."> Egwuche Sylvester O.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chronic Kidney Disease (CKD) is a significant cause of morbidity and mortality across developed and developing nations and is associated with increased risk. There are no existing electronic means of capturing and monitoring CKD in Nigeria. The work is aimed at developing a spatial data model that can be used to implement renal registries required for tracking and monitoring the spatial distribution of renal diseases by public health officers and patients. In this study, we have developed a spatial data model for a functional renal registry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20registry" title="renal registry">renal registry</a>, <a href="https://publications.waset.org/abstracts/search?q=health%20informatics" title=" health informatics"> health informatics</a>, <a href="https://publications.waset.org/abstracts/search?q=chronic%20kidney%20disease" title=" chronic kidney disease"> chronic kidney disease</a>, <a href="https://publications.waset.org/abstracts/search?q=interface" title=" interface"> interface</a> </p> <a href="https://publications.waset.org/abstracts/150377/development-of-a-spatial-data-for-renal-registry-in-nigeria-health-sector" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150377.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">212</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">292</span> Management of Renal Malignancies with IVC Thrombus: Our Experience</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sujeet%20Poudyal">Sujeet Poudyal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Renal cell carcinoma is the most common malignancy associated with Inferior vena cava (IVC) thrombosis. Radical nephrectomy with tumor thrombectomy provides durable cancer-free survival. Other renal malignancies like Wilms’ tumors are also associated with IVC thrombus. We describe our experience with the management of renal malignancies associated with IVC thrombus. Methods: This prospective study included 28 patients undergoing surgery for renal malignancies associated with IVC thrombus from February 2017 to March 2023. Demographics of patients, types of renal malignancy, level of IVC thrombus, intraoperative details, need for venovenous bypass, cardiopulmonary bypass and postoperative outcomes were all documented. Results: Out of a total of 28 patients, 24 patients had clear cell Renal Cell Carcinoma,1 had renal osteosarcoma and 3 patients had Wilms tumor. The levels. of thrombus were II in eight, III in seven, and IV in six patients. The mean age of RCC was 62.81±10.2 years, renal osteosarcoma was 26 years and Wilms tumor was 23 years. There was a need for venovenous bypass in four patients and cardiopulmonary bypass in four patients, and the Postoperative period was uneventful in most cases except for two mortalities, one in Level III due to pneumonia and one in Level IV due to sepsis. All cases followed up till now have no local recurrence and metastasis except one case of RCC with Level IV IVC thrombus, which presented with paraaortic nodal recurrence and is currently managed with sunitinib. Conclusion: The complexity in the management of renal malignancy with IVC thrombus increases with the level of IVC thrombus. As radical nephrectomy with tumor thrombectomy provides durable cancer-free survival in most cases, the surgery should be undertaken in an expert and experienced setup with a strong cardiovascular backup to minimize morbidity and mortality associated with the procedure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20malignancy" title="renal malignancy">renal malignancy</a>, <a href="https://publications.waset.org/abstracts/search?q=IVC%20thrombus" title=" IVC thrombus"> IVC thrombus</a>, <a href="https://publications.waset.org/abstracts/search?q=radical%20nephrectomy%20with%20tumor%20thrombectomy" title=" radical nephrectomy with tumor thrombectomy"> radical nephrectomy with tumor thrombectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20cell%20carcinoma" title=" renal cell carcinoma"> renal cell carcinoma</a> </p> <a href="https://publications.waset.org/abstracts/168963/management-of-renal-malignancies-with-ivc-thrombus-our-experience" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/168963.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">62</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">291</span> Bifid Ureters: Arising Directly from the Separate Calyces and Renal Pelvis of the Kidney: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yuri%20Seu">Yuri Seu</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyun%20Jin%20Park"> Hyun Jin Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Jin%20Seo%20Park"> Jin Seo Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Yong-Suk%20Moon"> Yong-Suk Moon</a>, <a href="https://publications.waset.org/abstracts/search?q=HongtaeKim"> HongtaeKim</a>, <a href="https://publications.waset.org/abstracts/search?q=Mi-Sun%20Hur"> Mi-Sun Hur</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present case report describes bifid ureters arising directly from the separate calyces and renal pelvis of the kidney. It was a single common ureter leading away from the bladder, which was separated into incompletely duplicated ureters near the level of the anterior superior iliac supine. These two branches then entered the left kidney through their own courses. Each ureter traveled anterior and posterior to the renal vein, respectively. These two ureters formed a Y-shaped pattern. One ureter coursed anterior to the renal vein with shorter length, and it terminated at the renal pelvis that was divided into major calices in approximately lower two thirds of the kidney. The other ureter coursed posterior to the renal vein with longer length, terminating at approximately the upper third of the kidney. The renal calices in the upper third of the kidney were directly connected to the posterior ureter, whereas the other major calices in the lower two thirds of the kidney formed the renal pelvis connecting to the anterior ureter. Thus, convergence of the major calices was separated according to the terminations of two ureters. These anomalous ureters were traced to the calices of the kidney, thereby providing a reference of a rare variation of the ureter. The bifid ureters arising from the separate calyces and renal pelvis should be considered by radiologists when evaluating images and diagnosing possible complications of these anomalies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bifid%20ureters" title="bifid ureters">bifid ureters</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=major%20calices" title=" major calices"> major calices</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20pelvis" title=" renal pelvis"> renal pelvis</a> </p> <a href="https://publications.waset.org/abstracts/167715/bifid-ureters-arising-directly-from-the-separate-calyces-and-renal-pelvis-of-the-kidney-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167715.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">86</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">290</span> Renal Complications in Patients with Falciparum Malaria </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saira%20Baloch">Saira Baloch</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohsin%20Ali%20Baloch"> Mohsin Ali Baloch </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Malaria is a potentially life-threatening disease and also a major public health problem in Pakistan. Renal failure is an emerging problem correlated with morbidity and mortality, however can be diagnosed and treated in the early stages. Objectives: To elucidate the biochemical renal parameters in patients with falciparum malaria and comparison with healthy control subjects. Method: 80 patients, who were diagnosed to be affected by falciparum malaria. Detailed history, general physical and systemic examination and necessary pathological, biochemical renal laboratory parameters and investigations were done. Results: Among the 80 patients, 43 were males and 37 were females. All patients were infected with P. falciparum. All patients had increased serum creatinine and urea levels and urine output of less than 400 ml/day were categorized as suffering from renal failure. Conclusion: Patients infected with P. falciparum are at an increased risk of developing renal failure when compared to patients infected with other complications. P. vivax has massive potential to cause life threatening complications and even death. Further research is required to understand the exact pathogenesis of various complications encountered in vivax malaria. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=falciparum%20malaria" title="falciparum malaria">falciparum malaria</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20failure" title=" renal failure"> renal failure</a>, <a href="https://publications.waset.org/abstracts/search?q=biochemical%20parameters" title=" biochemical parameters"> biochemical parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=pathogenesis" title=" pathogenesis"> pathogenesis</a> </p> <a href="https://publications.waset.org/abstracts/14798/renal-complications-in-patients-with-falciparum-malaria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14798.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">387</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">289</span> Renal Transplant, Pregnancy, and Complications: A Literature Review </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sara%20Iqbal">Sara Iqbal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction:Renal transplant is increasingly one of the most popular transplants within the UK; with an aging population along with obesity epidemic we are witnessing increasing rates of diabetes – one of the commonest indications for renal transplant. However, the demand is far greater than supply. Many donors are provided by women of child-bearing age; however the long-term effects are still uncertain. Aim:Determine pregnancy outcomes and complications of women of child-bearing age following renal donation. Methods: A review of the current available literature was preformed using MEDLINE and EMBASE up to 2014. Search criteria included key terms such as pregnancy outcome post-renal donor, pregnancy outcomes and complications. Relevant articles were selected based on pure methodological medical research, after careful analysis, they were recorded within this review. Results: Out of 1141 women involved in transplant studies, 574 pregnancies reported having donated a single-renal donor prior to pregnancy. Of which a staggering miscarriage rate 32.4% (n=186) was reported, amongst this other complications included gestational hypertension of 10% (n=59) and gestational diabetes 2.3% (n=13). Other significantly noted complications included chronic hypertension, low-birth weights, and pregnancy-related death. Conclusions: After unilateral renal donor transplant, haemodynamics change along with pregnancy, predisposing women to developing several complications compared to pregnancies with no history any renal-donor transplant. Despite this, further investigation is required in order to accurately determine the safety of renal-donors in women of child-bearing age. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20transplant" title="renal transplant">renal transplant</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=complications" title=" complications"> complications</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20and%20health%20sciences" title=" medical and health sciences "> medical and health sciences </a> </p> <a href="https://publications.waset.org/abstracts/17993/renal-transplant-pregnancy-and-complications-a-literature-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17993.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">288</span> Clinical Profile of Renal Diseases in Children in Tertiary Care Centre</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jyoti%20Agrawal">Jyoti Agrawal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Renal diseases in children and young adult can be difficult to diagnose early as it may present only with few symptoms, tends to have different course than adult and respond variously to different treatment. The pattern of renal disease in children is different from developing countries as compared to developed countries. Methods: This study was a hospital based prospective observational study carried from March, 2014 to February 2015 at BP Koirala institute of health sciences. Patients with renal disease, both inpatient and outpatient from birth to 14 years of age were enrolled in the study. The diagnosis of renal disease was be made on clinical and laboratory criteria. Results: Total of 120 patients were enrolled in our study which contributed to 3.74% % of total admission. The commonest feature of presentation was edema (75%), followed by fever (65%), hypertension (60%), decreased urine output (45%) and hematuria (25%). Most common diagnosis was acute glomerulonephritis (40%) followed by Nephrotic syndrome (25%) and urinary tract infection (25%). Renal biopsy was done for 10% of cases and most of them were steroid dependent nephrotic syndrome. 5% of our cases expired because of multiorgan dysfunction syndrome, sepsis and acute kidney injury. Conclusion: Renal disease contributes to a large part of hospital pediatric admission as well as mortality and morbidity to the children. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glomerulonephritis" title="glomerulonephritis">glomerulonephritis</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrotic%20syndrome" title=" nephrotic syndrome"> nephrotic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20disease" title=" renal disease"> renal disease</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20tract%20infection" title=" urinary tract infection"> urinary tract infection</a> </p> <a href="https://publications.waset.org/abstracts/79003/clinical-profile-of-renal-diseases-in-children-in-tertiary-care-centre" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79003.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">426</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">287</span> Comparison of the Classification of Cystic Renal Lesions Using the Bosniak Classification System with Contrast Enhanced Ultrasound and Magnetic Resonance Imaging to Computed Tomography: A Prospective Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dechen%20Tshering%20Vogel">Dechen Tshering Vogel</a>, <a href="https://publications.waset.org/abstracts/search?q=Johannes%20T.%20Heverhagen"> Johannes T. Heverhagen</a>, <a href="https://publications.waset.org/abstracts/search?q=Bernard%20Kiss"> Bernard Kiss</a>, <a href="https://publications.waset.org/abstracts/search?q=Spyridon%20Arampatzis"> Spyridon Arampatzis </a> </p> <p class="card-text"><strong>Abstract:</strong></p> In addition to computed tomography (CT), contrast enhanced ultrasound (CEUS), and magnetic resonance imaging (MRI) are being increasingly used for imaging of renal lesions. The aim of this prospective study was to compare the classification of complex cystic renal lesions using the Bosniak classification with CEUS and MRI to CT. Forty-eight patients with 65 cystic renal lesions were included in this study. All participants signed written informed consent. The agreement between the Bosniak classifications of complex renal lesions ( ≥ BII-F) on CEUS and MRI were compared to that of CT and were tested using Cohen’s Kappa. Sensitivity, specificity, positive and negative predictive values (PPV/NPV) and the accuracy of CEUS and MRI compared to CT in the detection of complex renal lesions were calculated. Twenty-nine (45%) out of 65 cystic renal lesions were classified as complex using CT. The agreement between CEUS and CT in the classification of complex cysts was fair (agreement 50.8%, Kappa 0.31), and was excellent between MRI and CT (agreement 93.9%, Kappa 0.88). Compared to CT, MRI had a sensitivity of 96.6%, specificity of 91.7%, a PPV of 54.7%, and an NPV of 54.7% with an accuracy of 63.1%. The corresponding values for CEUS were sensitivity 100.0%, specificity 33.3%, PPV 90.3%, and NPV 97.1% with an accuracy 93.8%. The classification of complex renal cysts based on MRI and CT scans correlated well, and MRI can be used instead of CT for this purpose. CEUS can exclude complex lesions, but due to higher sensitivity, cystic lesions tend to be upgraded. However, it is useful for initial imaging, for follow up of lesions and in those patients with contraindications to CT and MRI. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bosniak%20classification" title="Bosniak classification">Bosniak classification</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=contrast%20enhanced%20ultrasound" title=" contrast enhanced ultrasound"> contrast enhanced ultrasound</a>, <a href="https://publications.waset.org/abstracts/search?q=cystic%20renal%20lesions" title=" cystic renal lesions"> cystic renal lesions</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20resonance%20imaging" title=" magnetic resonance imaging"> magnetic resonance imaging</a> </p> <a href="https://publications.waset.org/abstracts/111885/comparison-of-the-classification-of-cystic-renal-lesions-using-the-bosniak-classification-system-with-contrast-enhanced-ultrasound-and-magnetic-resonance-imaging-to-computed-tomography-a-prospective-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/111885.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">143</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">286</span> History of Pediatric Renal Pathology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Elbaba">Mostafa Elbaba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Because childhood renal diseases are grossly different compared to adult diseases, pediatric nephrology was founded as a specialty in 1965. Renal pathology specialty was introduced at the London Ciba Symposium in 1961. The history of renal pathology can be divided into two eras: one starting in the 1650s with the invention of the microscope, the second in the 1950s with the implementation of renal biopsy, and the presence of electron microscopy and immunofluorescence study. Prior to the 1950s, the study of diseased human kidneys was restricted to postmortem examination by gross pathology. In 1827, Richard Bright first described his triad of kidney disease, which was confirmed by morbid kidney changes at autopsy. In 1905 Friedrich Mueller coined the term “nephrosis” describing the inflammatory form of “degenerative” diseases, and later F. Munk added the term “lipoid nephrosis”. The most profound influence on renal diseases’ classification came from the publication of Volhard and Fahr in 1914. In 1899, Carl Max Wilhelm Wilms described Wilms' tumor of the kidneys in children. Chronic pyelonephritis was a popular renal diagnosis and the most common cause of uremia until the 1960s. Although kidney biopsy had been used early in the 1930s for renal tumors, the earliest reports of its use in the diagnosis of medical kidney disease were by Iversen and Brun in 1951, followed by Alwall in 1952, then by Pardo in 1953. The earliest intentional renal biopsies were done in 1944 by Nils Alwall, while the procedure was abandoned after the death of one of his 13 patients who biopsied. In 1950, Antonino Perez-Ara attempted renal biopsies, but his results were missed because of an unpopular journal publication. In the year 1951, Claus Brun and Poul Iverson developed the biopsy procedure using an aspiration technique. Popularizing renal biopsy practice is accredited to Robert Kark, who published his distinct work in 1954. He perfected the technique of renal biopsy in the prone position using the Vim-Silverman needle and used intravenous pyelography to improve the localization of the kidney. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=history" title="history">history</a>, <a href="https://publications.waset.org/abstracts/search?q=medicine" title=" medicine"> medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrology" title=" nephrology"> nephrology</a>, <a href="https://publications.waset.org/abstracts/search?q=pediatrics" title=" pediatrics"> pediatrics</a>, <a href="https://publications.waset.org/abstracts/search?q=pathology" title=" pathology"> pathology</a> </p> <a href="https://publications.waset.org/abstracts/173746/history-of-pediatric-renal-pathology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173746.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">59</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">285</span> Effect of Omeprazole on the Renal Cortex of Adult Male Albino Rats and the Possible Protective Role of Ginger: Histological and Immunohistochemical study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nashwa%20A.%20Mohamed">Nashwa A. Mohamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Omeprazole is a proton pump inhibitor used commonly in the treatment of acid-peptic disorders. Although omeprazole is generally well tolerated, serious adverse effects such as renal failure have been reported. Ginger is an antioxidant that could play a protective role in models of experimentally induced nephropathies. Aim of the work: The aim of this work was to study the possible histological changes induced by omeprazole on renal cortex and evaluate the possible protective effect of ginger on omeprazole-induced renal damage in adult male albino rats. Materials and methods: Twenty-four adult male albino rats divided into four groups (six rats each) were used in this study. Group I served as the control group. Rats of group II received only an aqueous extract of ginger daily for 3 months through a gastric tube. Rats of group III were received omeprazole orally through a gastric tube for 3 months. Rats of group IV were given both ginger and omeprazole at the same doses and through the same routes as the previous two groups. At the end of the experiment, the rats were sacrificed. Renal tissue samples were processed for light, immunohistochemical and electron microscopic examination. The obtained results were analysed morphometrically and statistically. Results: Omeprazole caused several histological changes in the form of loss of normal appearance of renal cortex with degenerative changes in the renal corpuscle and tubules. Cellular infilteration was also observed. The filteration barrier was markedly affected. Ginger ameliorated the omeprazole-induced histological changes. Conclusion: Omeprazole induced injurious effects on renal cortex. Coadministration of ginger can ameliorate the histological changes induced by omeprazole. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ginger" title="ginger">ginger</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=omeprazole" title=" omeprazole"> omeprazole</a>, <a href="https://publications.waset.org/abstracts/search?q=rat" title=" rat"> rat</a> </p> <a href="https://publications.waset.org/abstracts/29467/effect-of-omeprazole-on-the-renal-cortex-of-adult-male-albino-rats-and-the-possible-protective-role-of-ginger-histological-and-immunohistochemical-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29467.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">252</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">284</span> Resilience in Patients with Chronic Kidney Disease in Hemodialysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gomes%20C.%20C.%20Izabel">Gomes C. C. Izabel</a>, <a href="https://publications.waset.org/abstracts/search?q=Lanzotti%20B.%20Rafaela"> Lanzotti B. Rafaela</a>, <a href="https://publications.waset.org/abstracts/search?q=Orlandi%20S.%20Fabiana"> Orlandi S. Fabiana</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chronic Kidney Disease is considered a serious public health problem. The exploitation of resilience has been guided by studies conducted in various contexts, especially in hemodialysis, since the impact of diagnosis and restrictions produced during the treatment process because, despite advances in treatment, remains the stigma of the disease and the feeling of pain, hopelessness, low self-esteem and disability. The objective was to evaluate the level of resilience of patients in chronic renal dialysis. This is a descriptive, correlational, cross and quantitative research. The sample consisted of 100 patients from a Renal Replacement Therapy Unit in the countryside of São Paulo. For data collection were used the characterization instrument of Participants and the Resilience Scale. There was a predominance of males (70.0%) were Caucasian (45.0%) and had completed elementary education (34.0%). The average score obtained through the Resilience Scale was 131.3 (± 20.06) points. The resiliency level submitted may be considered satisfactory. It is expected that this study will assist in the preparation of programs and actions in order to avoid possible situations of crises faced by chronic renal patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hemodialysis%20units" title="hemodialysis units">hemodialysis units</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20dialysis" title=" renal dialysis"> renal dialysis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20insufficiency%20chronic" title=" renal insufficiency chronic"> renal insufficiency chronic</a>, <a href="https://publications.waset.org/abstracts/search?q=resilience%20psychological" title=" resilience psychological"> resilience psychological</a> </p> <a href="https://publications.waset.org/abstracts/64848/resilience-in-patients-with-chronic-kidney-disease-in-hemodialysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64848.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">282</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">283</span> Protective Effect of Thymoquinone against Nephrotoxicity Induced by Cadmium in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amr%20A.%20Fouad">Amr A. Fouad</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamed%20A.%20Alwadaani"> Hamed A. Alwadaani</a>, <a href="https://publications.waset.org/abstracts/search?q=Iyad%20Jresat"> Iyad Jresat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present study investigated the protective effect of thymoquinone (TQ), against cadmium-induced kidney injury in rats. Cadmium chloride (1.2 mg Cd/kg/day, s.c.), was given for nine weeks. TQ treatment (40 mg/kg/day, p.o.) started on the same day of cadmium administration and continued for nine weeks. TQ significantly decreased serum creatinine, renal malondialdehyde and nitric oxide, and significantly increased renal reduced glutathione in rats received cadmium. Histopathological examination showed that TQ markedly minimized renal tissue damage induced by cadmium. Immunohistochemical analysis revealed that TQ markedly decreased the cadmium-induced expression of inducible nitric oxide synthase, tumor necrosis factor-α, cyclooxygenase-2, and caspase-3 in renal tissue. It was concluded that TQ significantly protected against cadmium nephrotoxicity in rats, through its antioxidant, antiinflammatory, and antiapoptotic actions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=thymoquinone" title="thymoquinone">thymoquinone</a>, <a href="https://publications.waset.org/abstracts/search?q=cadmium" title=" cadmium"> cadmium</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=rats" title=" rats"> rats</a> </p> <a href="https://publications.waset.org/abstracts/38527/protective-effect-of-thymoquinone-against-nephrotoxicity-induced-by-cadmium-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/38527.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">417</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">282</span> Spontaneous Tumour Lysis in Acute Myeloid Leukemia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rojith%20K.%20Balakrishnan">Rojith K. Balakrishnan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Spontaneous tumour lysis syndrome is a constellation of electrolyte abnormalities and an acute renal failure which occurs in the setting of rapid cell turnover prior to the administration of cytotoxic chemotherapy. While spontaneous tumour lysis well-described in patients with Burkitt lymphoma, it is thought to occur less commonly in patients with other hematological malignancies. We present a case of forty-year-old female who presented with features of acute renal failure, on further evaluation turned out to be a newly diagnosed acute myeloid leukemia with spontaneous tumour lysis best of our knowledge only three cases of AML with spontaneous tumour lysis has reported world wide. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AML" title="AML">AML</a>, <a href="https://publications.waset.org/abstracts/search?q=tumour%20lysis" title=" tumour lysis"> tumour lysis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20failure" title=" renal failure"> renal failure</a>, <a href="https://publications.waset.org/abstracts/search?q=myeloid%20leukemia" title=" myeloid leukemia"> myeloid leukemia</a> </p> <a href="https://publications.waset.org/abstracts/28705/spontaneous-tumour-lysis-in-acute-myeloid-leukemia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28705.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">294</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">281</span> Retrospective Analysis Demonstrates No Difference in Percutaneous Native Renal Biopsy Adequacy Between Nephrologists and Radiologists in University Hospital Crosshouse</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nicole%20Harley">Nicole Harley</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahmoud%20Eid"> Mahmoud Eid</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdurahman%20Tarmal"> Abdurahman Tarmal</a>, <a href="https://publications.waset.org/abstracts/search?q=Vishal%20Dey"> Vishal Dey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Histological sampling plays an integral role in the diagnostic process of renal diseases. Percutaneous native renal biopsy is typically performed under ultrasound guidance, with this service usually being provided by nephrologists. In some centers, there is a role for radiologists in performing renal biopsies. Previous comparative studies have demonstrated non-inferiority between outcomes of percutaneous native renal biopsies performed by nephrologists compared with radiologists. We sought to compare biopsy adequacy between nephrologists and radiologists in University Hospital Crosshouse. The online system SERPR (Scottish Electronic Renal Patient Record) contains information pertaining to patients who have undergone renal biopsies. An online search was performed to acquire a list of all patients who underwent renal biopsy between 2013 and 2020 in University Hospital Crosshouse. 355 native renal biopsies were performed in total across this 7-year period. A retrospective analysis was performed on these cases, with records and reports being assessed for: the total number of glomeruli obtained per biopsy, whether the number of glomeruli obtained was adequate for diagnosis, as per an internationally agreed standard, and whether a histological diagnosis was achieved. Nephrologists performed 43.9% of native renal biopsies (n=156) and radiologists performed 56.1% (n=199). The mean number of glomeruli obtained by nephrologists was 17.16+/-10.31. The mean number of glomeruli obtained by radiologists was 18.38+/-10.55. T-test demonstrated no statistically significant difference between specialties comparatively (p-value 0.277). Native renal biopsies are required to obtain at least 8 glomeruli to be diagnostic as per internationally agreed criteria. Nephrologists met these criteria in 88.5% of native renal biopsies (n=138) and radiologists met this criteria in 89.5% (n=178). T-test and Chi-squared analysis demonstrate there was no statistically significant difference between the specialties comparatively (p-value 0.663 and 0.922, respectively). Biopsies performed by nephrologists yielded tissue that was diagnostic in 91.0% (n=142) of sampling. Biopsies performed by radiologists yielded tissue that was diagnostic in 92.4% (n=184) of sampling. T-test and Chi-squared analysis demonstrate there was no statistically significant difference between the specialties comparatively (p-value 0.625 and 0.889, respectively). This project demonstrates that at University Hospital Crosshouse, there is no statistical difference between radiologists and nephrologists in terms of glomeruli acquisition or samples achieving a histological diagnosis. Given the non-inferiority between specialties demonstrated by previous studies and this project, this evidence could support the restructuring of services to allow more renal biopsies to be performed by renal services and allow reallocation of radiology department resources. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biopsy" title="biopsy">biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20imaging" title=" medical imaging"> medical imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrology" title=" nephrology"> nephrology</a>, <a href="https://publications.waset.org/abstracts/search?q=radiology" title=" radiology"> radiology</a> </p> <a href="https://publications.waset.org/abstracts/157526/retrospective-analysis-demonstrates-no-difference-in-percutaneous-native-renal-biopsy-adequacy-between-nephrologists-and-radiologists-in-university-hospital-crosshouse" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/157526.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">81</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">280</span> Pattern of Biopsy Proven Renal Disease and Association between the Clinical Findings with Renal Pathology in Eastern Nepal</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manish%20Subedi">Manish Subedi</a>, <a href="https://publications.waset.org/abstracts/search?q=Bijay%20Bartaula"> Bijay Bartaula</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashok%20R.%20Pant"> Ashok R. Pant</a>, <a href="https://publications.waset.org/abstracts/search?q=Purbesh%20Adhikari"> Purbesh Adhikari</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjib%20K.%20Sharma"> Sanjib K. Sharma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The pattern of glomerular disease varies worldwide. In absence of kidney disease/Kidney biopsy registry in Nepal, the exact etiology of different forms of glomerular disease is primarily unknown in our country. Method: We retrospectively analyzed 175 cases of renal biopsies performed from dated September 2014 to August 2016 at B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Results: The commonest indication for renal biopsy was nephrotic syndrome (34.9%), followed by Systemic lupus erythematosus with suspected renal involvement (22.3%). Majority of patients were in the 30-60 year bracket (57.2%), with the mean age of the patients being 35.37 years. The average number of glomeruli per core was 13, with inadequate sampling in 5.1%. IgA nephropathy (17%) was found to be the most common primary glomerular disease, followed by membranous nephropathy (14.6%) and FSGS (14.6%). The commonest secondary glomerular disease was lupus nephritis. Complications associated with renal biopsy were pain at biopsy site in 18% of cases, hematuria in 6% and perinephric hematoma in 4% cases. Conclusion: The commonest primary and secondary glomerular disease was IgA nephropathy and lupus nephritis respectively. The high prevalence of Systemic lupus erythematosus with lupus nephritis among Nepalese in comparison with other developing countries warrants further evaluation. As an initial attempt towards documentation of glomerular diseases in the national context, this study should serve as a stepping stone towards the eventual establishment of a full-fledged national registry of glomerular diseases in Nepal. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glomerular" title="glomerular">glomerular</a>, <a href="https://publications.waset.org/abstracts/search?q=Nepal" title=" Nepal"> Nepal</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20biopsy" title=" renal biopsy"> renal biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=systemic%20lupus%20erythematoses" title=" systemic lupus erythematoses"> systemic lupus erythematoses</a> </p> <a href="https://publications.waset.org/abstracts/80240/pattern-of-biopsy-proven-renal-disease-and-association-between-the-clinical-findings-with-renal-pathology-in-eastern-nepal" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80240.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">229</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">279</span> A Comparative, Epidemiological Study of Acute Renal Colic Presentations to Major Academic Emergency Departments in Doha, Qatar and Melbourne, Australia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sameer%20A.%20Pathan">Sameer A. Pathan</a>, <a href="https://publications.waset.org/abstracts/search?q=Biswadev%20Mitra"> Biswadev Mitra</a>, <a href="https://publications.waset.org/abstracts/search?q=Zain%20A.%20Bhutta"> Zain A. Bhutta</a>, <a href="https://publications.waset.org/abstracts/search?q=Isma%20Qureshi"> Isma Qureshi</a>, <a href="https://publications.waset.org/abstracts/search?q=Elle%20Spencer"> Elle Spencer</a>, <a href="https://publications.waset.org/abstracts/search?q=Asmaa%20A.%20Hameed"> Asmaa A. Hameed</a>, <a href="https://publications.waset.org/abstracts/search?q=Sana%20Nadeem"> Sana Nadeem</a>, <a href="https://publications.waset.org/abstracts/search?q=Ramsha%20Tahir"> Ramsha Tahir</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahzad%20Anjum"> Shahzad Anjum</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20A.%20Cameron"> Peter A. Cameron</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: This study aimed to compare epidemiology, clinical presentations, management and outcomes of renal colic presentations in two major academic centers and discuss potential implications of these results for the applicability of current evidence in the management of renal colic. Methods: We undertook a retrospective cohort study of patients with renal colic who presented to the Hamad General Hospital Emergency Department (HGH-ED), Qatar, and The Alfred ED, Melbourne, Australia, during a period of one year from August 1, 2012, to July 3, 2013. Cases were identified using ICD-9-CM codes, and an electronic template was used to record the data on predefined clinical variables. Results: A total of 12,223 from the HGH-ED and 384 from The Alfred ED were identified as renal colic presentations during the study period. The rate of renal colic presentations at the HGH-ED was 27.9 per 1000 ED visits compared to 6.7 per 1000 ED visits at The Alfred ED. Patients presenting to the HGH-ED were significantly younger [34.9 years (29.0- 43.4) than The Alfred ED [48 years (37-60); P < 0.001]. The median stone size was larger in the HGH-ED group [6 (4-8) mm] versus The Alfred ED group [4 (3-6) mm, P < 0.001]. The intervention rate in the stone-positive population was significantly higher in the HGH-ED group as opposed to The Alfred ED group (38.7% versus 11.9%, p<0.001). At the time of discharge, The Alfred ED group received less analgesic prescriptions (55.8% versus 83.5%, P < 0.001) and more tamsulosin prescriptions (25.3% versus 11.7%, P < 0.001). Conclusions: Renal colic presentations to the HGH-ED, Qatar, were younger, with larger stone size, compared to The Alfred ED, whereas, medical expulsion therapy use was higher at the Alfred ED. Differences in epidemiology should be considered while tailoring strategies for effective management of patients with renal colic in the given setting. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=kidney%20stones" title="kidney stones">kidney stones</a>, <a href="https://publications.waset.org/abstracts/search?q=urolithiasis" title=" urolithiasis"> urolithiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrolithiasis" title=" nephrolithiasis"> nephrolithiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20colic" title=" renal colic"> renal colic</a>, <a href="https://publications.waset.org/abstracts/search?q=epidemiology" title=" epidemiology"> epidemiology</a> </p> <a href="https://publications.waset.org/abstracts/78021/a-comparative-epidemiological-study-of-acute-renal-colic-presentations-to-major-academic-emergency-departments-in-doha-qatar-and-melbourne-australia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/78021.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">241</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">278</span> Hematuria Following Magnesium Sulfate Administration in a Pregnant Patient with Renal Tubular Acidosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jan%20Gayl%20Barcelon">Jan Gayl Barcelon</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Gorgonio"> N. Gorgonio</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Renal tubular acidosis, a medical condition that involves the accumulation of acid in the body due to failure of the kidneys to maintain normal urine and blood pH, is rarely encountered in pregnancy. The effect of renal tubular acidosis in pregnancy is not fully established. It may worsen during pregnancy and cause maternal and fetal morbidity. A 30-year-old primigravida was diagnosed with renal tubular acidosis at age 7, but due to uncontrolled disease progression, she developed rickets at age 10. She was first seen in our institution at eight weeks gestation and maintained on bicarbonate and potassium supplementation. At 26 weeks gestation, she was diagnosed with polyhydramnios, causing on and off irregular uterine contractions. At 30 weeks gestation, despite oral Nifedipine, premature labor was uncontrolled; hence she was admitted for tocolysis. With elevated creatinine (123 umol/L) and a normal blood urea nitrogen level (6.70 mmol/L), she was referred to Nephrology Service, which cleared the patient prior to MgSO₄ drip. Dosing of 4g MgSO₄ over 20 minutes followed by a maintenance of 2g/hour x 24 hours for neuroprotection and tocolysis was ordered. Two hours after MgSO₄ drip initiation, hematuria developed with adequate urine output. The infusion was immediately stopped. The serum magnesium level was high normal at 6.7 mEq/L. After 4 hours of renal clearance, the repeat serum magnesium level was normal (2.7 mEq/L) and with clear urine output. The patient was then given Nifedipine 30mg/tab, 3x a day which controlled the uterine contractions. At 37 weeks gestation, the patient delivered via primary low transverse Cesarean Section to a live female with a birthweight of 2470gm, appropriate for gestational age. The use of MgSO₄ for the control of premature labor in patients with chronic renal disease secondary to renal tubular can cause hematuria. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hematuria" title="hematuria">hematuria</a>, <a href="https://publications.waset.org/abstracts/search?q=magnesium%20sulfate" title=" magnesium sulfate"> magnesium sulfate</a>, <a href="https://publications.waset.org/abstracts/search?q=premature%20labor" title=" premature labor"> premature labor</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20tubular%20acidosis" title=" renal tubular acidosis"> renal tubular acidosis</a> </p> <a href="https://publications.waset.org/abstracts/137584/hematuria-following-magnesium-sulfate-administration-in-a-pregnant-patient-with-renal-tubular-acidosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137584.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">129</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">277</span> Renal Angiomyolipoma Rupture Following COVID-19 Infection: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Abdurabu">Mohammed Abdurabu</a>, <a href="https://publications.waset.org/abstracts/search?q=Akram%20Al-Warqi"> Akram Al-Warqi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ebrahim%20M.%20A.%20Ebrahim"> Ebrahim M. A. Ebrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Jouhar%20Kollari"> Jouhar Kollari</a>, <a href="https://publications.waset.org/abstracts/search?q=Salman%20Mirza"> Salman Mirza</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The novel coronavirus (COVID-19) is one of the most recent pandemics that invaded earth that left and still leaving hundreds of thousands of patients and ended with high morbidity and mortality rates with no clear cure till this moment. COVID-19 has been proven to be associated with pathologic changes in coagulation, characterized by either thromboembolic or bleeding events. We present this case of a 44-year-old male patient that presented to our Emergency Department with flank pain that later was found to have renal angiomyolipoma (AML) rupture during his COVID-19 infection, ultimately requiring admission for hemorrhage control via Interventional Radiology (IR) drainage. Here, we discuss the role of the front-line physicians and how they should keep a low threshold for the different presentations that could be associated with COVID-19 infection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=angiomyolipoma" title="angiomyolipoma">angiomyolipoma</a>, <a href="https://publications.waset.org/abstracts/search?q=COVID-19" title=" COVID-19"> COVID-19</a>, <a href="https://publications.waset.org/abstracts/search?q=renal" title=" renal"> renal</a>, <a href="https://publications.waset.org/abstracts/search?q=rupture" title=" rupture"> rupture</a> </p> <a href="https://publications.waset.org/abstracts/154529/renal-angiomyolipoma-rupture-following-covid-19-infection-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154529.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">131</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">276</span> Ocular Complications, Adverse Effects of the Procedure, Side-effects of Medications Used for Graft Survival, and Preventable Vision Loss in Live-related Renal Transplant Recipients: Experience at a Transplant Centre in Pakistan</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatema%20Ali%20Lanewala">Fatema Ali Lanewala</a>, <a href="https://publications.waset.org/abstracts/search?q=Akhtar%20Jamal%20Khan"> Akhtar Jamal Khan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ocular complications in renal transplant recipients at the biggest transplant center in Pakistan were seen to be diverse, multiple, and sight-threatening. These complications could mainly be due to the primary disease causing renal failure, the process of transplantation, and/or the medications used pre and post-transplantation. A retrospective case series recently published in the Journal of Pakistan Medical Association highlights the common ocular pathologies encountered in renal transplant population. Majority of the patients suffered from cataract, which is a known side-effect of long-term steroids routinely used for graft survival. There was a unique finding in Pakistani population, never reported before from any other transplant centre world over; a large number of recipients was reported to be suffering from night blindness, which significantly improved on vitamin A supplementation. There were a variety of other ocular complications seen which emphasizes the necessity of ocular care and routine examination of transplant recipient’s eyes by an ophthalmologist in order to avoid visual compromise and improve the quality of life of the transplant recipient. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cataract" title="cataract">cataract</a>, <a href="https://publications.waset.org/abstracts/search?q=night%20blindness" title=" night blindness"> night blindness</a>, <a href="https://publications.waset.org/abstracts/search?q=ocular%20complications" title=" ocular complications"> ocular complications</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20transplantation" title=" renal transplantation"> renal transplantation</a> </p> <a href="https://publications.waset.org/abstracts/166796/ocular-complications-adverse-effects-of-the-procedure-side-effects-of-medications-used-for-graft-survival-and-preventable-vision-loss-in-live-related-renal-transplant-recipients-experience-at-a-transplant-centre-in-pakistan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166796.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">106</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">275</span> Etiological Factors for Renal Cell Carcinoma: Five-Year Study at Mayo Hospital Lahore</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Umar%20Hassan">Muhammad Umar Hassan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Renal cell carcinoma is a subset of kidney cancer that arises in the lining of DCT and is present in parenchymal tissue. Diagnosis is based on lab reports, including urinalysis, renal function tests (RFTs), and electrolyte balance, along with imaging techniques. Organ failure and other complications have been commonly observed in these cases. Over the years, the presentation of patients has varied, so carcinoma was classified on the basis of site, shape, and consistency for detailed analysis. Lifestyle patterns and occupational history were inquired about and recorded. Methods: Data from 100 patients presenting to the oncology and nephrology department of Mayo Hospital in the year 2015-2020 were included in this retrospective study on a random basis. The study was specifically focused on three risk factors. Smoking, occupational exposures, and Hakim medicine are taken by the patient for any cause. After procurement of data, follow-up contacts of these patients were established, resulting in a detailed analysis of lifestyle. Conclusion: The inference drawn is a direct causal link between smoking, industrial workplace exposure, and Hakim medicine with the development of Renal Cell Carcinoma. It was shown in the majority of the patients and hence confirmed our hypothesis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20cell%20carcinoma" title="renal cell carcinoma">renal cell carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20cancer" title=" kidney cancer"> kidney cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=clear%20cell%20carcinoma" title=" clear cell carcinoma"> clear cell carcinoma</a> </p> <a href="https://publications.waset.org/abstracts/161412/etiological-factors-for-renal-cell-carcinoma-five-year-study-at-mayo-hospital-lahore" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161412.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">102</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">274</span> Interdialytic Acupuncture Is an Add-on Option for Preserving Residual Renal Function: A Case Series Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lai%20Tzu-Hsuan">Lai Tzu-Hsuan</a>, <a href="https://publications.waset.org/abstracts/search?q=Lai%20Jung-Nien"> Lai Jung-Nien</a>, <a href="https://publications.waset.org/abstracts/search?q=Lin%20Jaung-Geng"> Lin Jaung-Geng</a>, <a href="https://publications.waset.org/abstracts/search?q=Kao%20Shung-Te"> Kao Shung-Te</a>, <a href="https://publications.waset.org/abstracts/search?q=Hsuan-Kuang%20Jung"> Hsuan-Kuang Jung</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Whether acupuncture therapy contributes to preserving residual renal function (RRF) remains largely unknown. This case series evidenced the potential beneficial effects of acupuncture for preserving RRF in five patients with the end-stage renal disease under hemodialysis (HD) treatment. Participants: Five patients on HD receiving eight sessions of weekly 30-min interdialytic acupuncture (Inter-A) with residual urine volume (rUV) and residual glomerular filtration rate (rGFR) recorded once every two weeks were included for analysis. Outcomes: Changes in rUV and rGFR calculated using 24-hour urine collection data were analyzed to assess RRF. Variations in hemoglobin, urea Kt/V and serum albumin levels measured monthly were analyzed to evaluate HD adequacy. Results: After eight Inter-A sessions, mean (standard deviation (SD)) rUV and rGFR increased from 612 (184) ml/day and 1.48 (.94) ml/min/1.73 m2 at baseline to 803(289) ml/day and 2.04(1.17) ml/min/1.73m2 at 2- and 4-week follow-up, respectively. The mean percentage difference increased by 31% in rUV and 38% in rGFR. Routine measurements on HD adequacy also showed improvement. Conclusions: Acupuncture might be an optional add-on treatment for HD population with poor control of water; however, further well-designed controlled trials are warranted. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=end-stage%20renal%20disease" title="end-stage renal disease">end-stage renal disease</a>, <a href="https://publications.waset.org/abstracts/search?q=hemodialysis" title=" hemodialysis"> hemodialysis</a>, <a href="https://publications.waset.org/abstracts/search?q=acupuncture" title=" acupuncture"> acupuncture</a>, <a href="https://publications.waset.org/abstracts/search?q=residual%20renal%20function" title=" residual renal function"> residual renal function</a>, <a href="https://publications.waset.org/abstracts/search?q=residual%20urine%20volume" title=" residual urine volume"> residual urine volume</a> </p> <a href="https://publications.waset.org/abstracts/137391/interdialytic-acupuncture-is-an-add-on-option-for-preserving-residual-renal-function-a-case-series-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137391.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">129</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">273</span> Effect of Green Coffee Bean Extract on Gentamicin Induced Acute Renal Failure in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amina%20Unis">Amina Unis</a>, <a href="https://publications.waset.org/abstracts/search?q=Samah%20S.%20El%20Basateeny"> Samah S. El Basateeny</a>, <a href="https://publications.waset.org/abstracts/search?q=Noha%20A.%20H.%20Nassef"> Noha A. H. Nassef</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Acute Renal Failure (ARF) is one of the most common problems encountered in hospitalized critically ill patients. In recent years great effort has been focused on the introduction of herbal medicine as a novel therapeutic agent for prevention of ARF. Hence, the current study was designed to investigate the effect of Green Coffee Bean Extract (GCBE) on gentamicin induced ARF in rats. Methods: The study was conducted on 60 male rats divided into six equal groups. Group 1 served as normal control group and GCBE was administered for 7 days at a dose of 20 mg/kg/day in group 2 and 40 mg/kg/day in group 3 to test the effect of GCBE on normal kidneys. ARF was induced by a daily intraperitoneal injection of gentamicin (80 mg/kg) for 7 days in group 4 (model group), group 5 (GCBE 20 mg/kg/day) and group 6 (GCBE 20 mg/kg/day). All rats were sacrificed after 7 days and blood was withdrawn for kidney function tests. Kidneys were removed for determination of renal oxidative stress markers and histopathological examination. Results: The present study showed that rats that received oral GCBE for 7 days without induction of ARF showed no significant change in all the assessed parameters in comparison to the normal control group, while rats in the groups that received oral GCBE for 7 days with induction of ARF showed a significant improvement in kidney functions tests (decrease in serum urea, serum creatinine, and blood urea nitrogen) when compared to the ARF model group. Moreover, there was significant amelioration in renal oxidative stress markers (renal malondialdehyde, renal superoxide dismutase) and renal histopathological changes in the GCBE treated groups along induction of ARF when compared to ARF model group. The most significant improvement was reported in the group where GCBE was administered for 7 days in a dose 40 mg/kg/day, along with induction of ARF. Conclusion: GCBE has a potential role in ameliorating renal damage involved in ARF mostly through its antioxidant effect. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=green%20coffee%20bean%20extract" title="green coffee bean extract">green coffee bean extract</a>, <a href="https://publications.waset.org/abstracts/search?q=gentamicin" title=" gentamicin"> gentamicin</a>, <a href="https://publications.waset.org/abstracts/search?q=acute%20renal%20failure" title=" acute renal failure"> acute renal failure</a>, <a href="https://publications.waset.org/abstracts/search?q=pharmacology" title=" pharmacology"> pharmacology</a> </p> <a href="https://publications.waset.org/abstracts/5296/effect-of-green-coffee-bean-extract-on-gentamicin-induced-acute-renal-failure-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/5296.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">272</span> Effects of Tenefovir Disiproxil Fumarate on the Renal Sufficiency of HIV Positive Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Londeka%20Ntuli">Londeka Ntuli</a>, <a href="https://publications.waset.org/abstracts/search?q=Frasia%20Oosthuizen"> Frasia Oosthuizen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Tenefovir disiproxil fumarate (TDF) is a nephrotoxic drug and has been proven to contribute to renal insufficiency necessitating intensive monitoring and management of adverse effects arising from prolonged exposure to the drug. TDF is one of the preferred first-line drugs used in combination therapy in most regions. There are estimated 300 000 patients being initiated on the Efavirenz/TDF/Emtricitabine first-line regimen annually in South Africa. It is against this background that this study aims to investigate the effects of TDF on renal sufficiency of HIV positive patients. Methodology: A retrospective quantitative study was conducted, analysing clinical charts of HIV positive patient’s older than 18 years of age and on a TDF-containing regimen for more than 1 year. Data were obtained from the analysis of patient files and was transcribed into Microsoft® Excel® spreadsheet. Extracted data were coded, categorised and analysed using STATA®. Results: A total of 275 patient files were included in this study. Renal function started decreasing after 3 months of treatment (with 93.5% patients having a normal EGFR), and kept on decreasing as time progressed with only 39.6% normal renal function at year 4. Additional risk factors for renal insufficiency included age below 25, female gender, and additional medication. Conclusion: It is clear from this study that the use of TDF necessitates intensive monitoring and management of adverse effects arising from prolonged exposure to the drug. The findings from this study generated pertinent information on the safety profile of the drug TDF in a resource-limited setting of a public health institution. The appropriate management is of tremendous importance in the South African context where the majority of HIV positive individuals are on the TDF containing regimen; thus it is beneficial to ascertain the possible level of toxicities these patients may be experiencing. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20insufficiency" title="renal insufficiency">renal insufficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=tenefovir" title=" tenefovir"> tenefovir</a>, <a href="https://publications.waset.org/abstracts/search?q=HIV" title=" HIV"> HIV</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title=" risk factors "> risk factors </a> </p> <a href="https://publications.waset.org/abstracts/96854/effects-of-tenefovir-disiproxil-fumarate-on-the-renal-sufficiency-of-hiv-positive-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96854.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">121</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">271</span> Cognitive Impairment in Chronic Renal Patients on Hemodialysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fabiana%20Souza%20Orlandi">Fabiana Souza Orlandi</a>, <a href="https://publications.waset.org/abstracts/search?q=Juliana%20Gomes%20Duarte"> Juliana Gomes Duarte</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabriela%20Dutra%20Gesualdo"> Gabriela Dutra Gesualdo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chronic renal disease (CKD), accompanied by hemodialysis, causes chronic renal failure in a number of situations that compromises not only physical, personal and environmental aspects, but also psychological, social and family aspects. Objective: To verify the level of cognitive impairment of chronic renal patients on hemodialysis. Methodology: This is a descriptive, cross-sectional study. The present study was performed in a Dialysis Center of a city in the interior of the State of São Paulo. The inclusion criteria were: being 18 years or older; have a medical diagnosis of CKD; being in hemodialysis treatment in this unit; and agree to participate in the research, with the signature of the Informed Consent (TCLE). A total of 115 participants were evaluated through the Participant Characterization Instrument and the Addenbrooke Cognitive Exam - Revised Version (ACE-R), being scored from 0 to 100, stipulating the cut-off note for the complete battery <78 and subdivided into five domains: attention and guidance; memory; fluency; language; (66.9%) and caucasian (54.7%), 53.7 (±14.8) years old. Most of the participants were retired (74.7%), with incomplete elementary schooling (36.5%) and the average time of treatment was 46 months. Most of the participants (61.3%) presented impairment in the area of attention and orientation, 80.4% in the spatial visual domain. Regarding the total ACE-R score, 75.7% of the participants presented scores below the established cut grade. Conclusion: There was a high percentage (75.7%) below the cut-off score established for ACE-R, suggesting that there may be some cognitive impairment among these participants, since the instrument only performs a screening on cognitive health. The results of the study are extremely important so that possible interventions can be traced in order to minimize impairment, thus improving the quality of life of chronic renal patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cognition" title="cognition">cognition</a>, <a href="https://publications.waset.org/abstracts/search?q=chronic%20renal%20insufficiency" title=" chronic renal insufficiency"> chronic renal insufficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=adult%20health" title=" adult health"> adult health</a>, <a href="https://publications.waset.org/abstracts/search?q=dialysis" title=" dialysis"> dialysis</a> </p> <a href="https://publications.waset.org/abstracts/64903/cognitive-impairment-in-chronic-renal-patients-on-hemodialysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64903.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">365</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">270</span> The Biochemical and Radiographic Evaluation of the Non-Metastatic Bone Disease in Patients with Renal Cell Carcinoma Undergoing Hemodialysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aliakbar%20Hafezi">Aliakbar Hafezi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jalal%20Taherian"> Jalal Taherian</a>, <a href="https://publications.waset.org/abstracts/search?q=Jamshid%20Abedi"> Jamshid Abedi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahsa%20Elahi"> Mahsa Elahi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Bones are commonly affected by renal cell carcinoma (RCC) (primarily or secondary), and this condition causes bone fragility. The aim of this study was to evaluate the diagnostic value of noninvasive methods for the diagnosis of ROD in RCC patients on hemodialysis (HD) in northern Iran. Methods: In this cross-sectional study, 50 RCC patients with ESRD referred to dialysis units in northern Iran during 2021-2024 were randomly selected and investigated. The biochemical and radiographic evaluation of ROD and its subtypes was performed, and then all patients underwent bone biopsy and histopathological study, and finally, the diagnostic value of the noninvasive methods was assessed. Results: The mean age of patients was 58.9 ± 11.7 years, and 27 cases (54.0%) were female. 38 (76.0%) of RCC patients with ESRD had ROD, and 12 patients (24.0%) had no evidence of bone disorders. The sensitivity, specificity, positive and predictive values and accuracy of the noninvasive methods for the diagnosis of ROD were 92%, 82%, 95%, 75% and 90%, respectively. Conclusion: This study showed that the frequency of ROD in RCC patients with ESRD in northern Iran was high and the biochemical and radiographic markers have a high diagnostic value for ROD as well as histopathological assessment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=renal%20cell%20carcinoma" title="renal cell carcinoma">renal cell carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20osteodystrophy" title=" renal osteodystrophy"> renal osteodystrophy</a>, <a href="https://publications.waset.org/abstracts/search?q=hemodialysis" title=" hemodialysis"> hemodialysis</a>, <a href="https://publications.waset.org/abstracts/search?q=non-metastatic" title=" non-metastatic"> non-metastatic</a> </p> <a href="https://publications.waset.org/abstracts/194684/the-biochemical-and-radiographic-evaluation-of-the-non-metastatic-bone-disease-in-patients-with-renal-cell-carcinoma-undergoing-hemodialysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194684.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">6</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">269</span> Total Plaque Area in Chronic Renal Failure</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hern%C3%A1n%20A.%20Perez">Hernán A. Perez</a>, <a href="https://publications.waset.org/abstracts/search?q=Luis%20J.%20Armando"> Luis J. Armando</a>, <a href="https://publications.waset.org/abstracts/search?q=N%C3%A9stor%20H.%20Garc%C3%ADa"> Néstor H. García</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background and aims Cardiovascular disease rates are very high in patients with renal failure (CRF), but the underlying mechanisms are incompletely understood. Traditional cardiovascular risk factors do not explain the increased risk, and observational studies have observed paradoxical or absent associations between classical risk factors and mortality in dialysis patients. A large randomized controlled trial, the 4D Study, the AURORA and the ALERT study found that statin therapy in CRF do not reduce cardiovascular events. These results may be the results of ‘accelerated atherosclerosis’ observed on these patients. The objective of this study was to investigate if carotid total plaque area (TPA), a measure of carotid plaque burden growth is increased at progressively lower creatinine clearance in patients with CRF. We studied a cohort of patients with CRF not on dialysis, reasoning that risk factor associations might be more easily discerned before end stage renal disease. Methods: The Blossom DMO Argentina ethics committee approved the study and informed consent from each participant was obtained. We performed a cohort study in 412 patients with Stage 1, 2 and 3 CRF. Clinical and laboratory data were obtained. TPA was determined using bilateral carotid ultrasonography. Modification of Diet in Renal Disease estimation formula was used to determine renal function. ANOVA was used when appropriate. Results: Stage 1 CRF group (n= 16, 43±2yo) had a blood pressure of 123±2/78±2 mmHg, BMI 30±1, LDL col 145±10 mg/dl, HbA1c 5.8±0.4% and had the lowest TPA 25.8±6.9 mm2. Stage 2 CRF (n=231, 50±1 yo) had a blood pressure of 132±1/81±1 mmHg, LDL col 125±2 mg/dl, HbA1c 6±0.1% and TPA 48±10mm2 ( p< 0.05 vs CRF stage 1) while Stage 3 CRF (n=165, 59±1 yo) had a blood pressure of 134±1/81±1, LDL col 125±3 mg/dl, HbA1c 6±0.1% and TPA 71±6mm2 (p < 0.05 vs CRF stage 1 and 2). Conclusion: Our data indicate that TPA increases along the renal function deterioration, and it is not related with the LDL cholesterol and triglycerides levels. We suggest that mechanisms other than the classics are responsible for the observed excess of cardiovascular disease in CKD patients and finally, determination of total plaque area should be used to measure effects of antiatherosclerotic therapy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hypertension" title="hypertension">hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=chronic%20renal%20failure" title=" chronic renal failure"> chronic renal failure</a>, <a href="https://publications.waset.org/abstracts/search?q=atherosclerosis" title=" atherosclerosis"> atherosclerosis</a>, <a href="https://publications.waset.org/abstracts/search?q=cholesterol" title=" cholesterol"> cholesterol</a> </p> <a href="https://publications.waset.org/abstracts/47919/total-plaque-area-in-chronic-renal-failure" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47919.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">271</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">268</span> Prevalence of Lupus Glomerulonephritis in Renal Biopsies in an Eastern Region of the Arab World</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Fayez%20Al%20Homsi">M. Fayez Al Homsi</a>, <a href="https://publications.waset.org/abstracts/search?q=Reem%20Al%20Homsi"> Reem Al Homsi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Renal disease is a major cause of morbidity and mortality. Glomerular diseases make a small portion of the renal disease. Lupus glomerulonephritis (GN) is the commonest among the GN of systemic diseases. More than a hundred and eighty-eight consecutive renal biopsies are performed and evaluated for clinically suspected glomerular diseases over a period of two years. As in a standard practice after receiving the ultrasound-guided renal biopsies, the fresh biopsy is divided to three parts, one part is frozen for immunofluorescence evaluation, the second part is placed in 4% glutaraldehyde for electron microscopic evaluation, and the third part is placed in 10% buffered formalin for light microscopic evaluation. Primary glomerular diseases are detected in 83 biopsies; glomerulonephritis (GN) of systemic diseases are identified in 88, glomerular lesions in vascular diseases in 3, glomerular lesions in metabolic diseases in 7, hereditary nephropathies in 2, end-stage kidney in 2, and glomerular lesions in transplantation in 3 biopsies. Among the primary lesions, focal segmental glomerulosclerosis (28) and mesangial proliferative GN (26) were the most common. Lupus GN (67) and Ig A nephropathy (20) were the most common of the GN of systemic diseases. Lupus nephritis biopsies included one biopsy diagnosed as class 1 (normal), 17 biopsies class 2 (mesangial proliferation), 5 biopsies class 3 (focal proliferative GN), 39 biopsies class 4 diffuse proliferative GN), 3 biopsies class 5 (membranous GN), and 2 biopsies class 6 (crescentic GN). Lupus GN is the most common among GN of systemic diseases. While diabetes is very common here, diabetic GN (3 biopsies) is not as common as might one expects. Most likely this is due to sampling and reluctance on part of nephrologists and patients in sampling the kidney in diabetes mellitus. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes" title="diabetes">diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=glomerulonephritis" title=" glomerulonephritis"> glomerulonephritis</a>, <a href="https://publications.waset.org/abstracts/search?q=lupus" title=" lupus"> lupus</a>, <a href="https://publications.waset.org/abstracts/search?q=mesangial%20proliferation" title=" mesangial proliferation"> mesangial proliferation</a>, <a href="https://publications.waset.org/abstracts/search?q=nephropathy" title=" nephropathy"> nephropathy</a> </p> <a href="https://publications.waset.org/abstracts/97789/prevalence-of-lupus-glomerulonephritis-in-renal-biopsies-in-an-eastern-region-of-the-arab-world" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/97789.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">131</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">267</span> Spectrum of Acute Kidney Injury in Obstetrics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Seema%20%20Chopra">Seema Chopra</a>, <a href="https://publications.waset.org/abstracts/search?q=Amandeep%20Kaur"> Amandeep Kaur</a>, <a href="https://publications.waset.org/abstracts/search?q=Vanita%20Suri"> Vanita Suri</a>, <a href="https://publications.waset.org/abstracts/search?q=Shalini%20Gainder"> Shalini Gainder</a>, <a href="https://publications.waset.org/abstracts/search?q=Minakshi%20Rohilla"> Minakshi Rohilla</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Acute kidney injury (AKI) associated with pregnancy is a serious medical complication which can lead to significant maternal as well as perinatal morbidity and mortality. Material and methods: This prospective observational study was carried out in the Obstetrics and Gynaecology department and dialysis unit of Nephrology department of PGIMER, Chandigarh from July 2013 to June 2014. Forty antenatal/postnatal/postabortal patients who fulfilled the AKIN criteria were enrolled in the study. All patients were followed up till 3 months postpartum. Results: Majority of the patients 23/40 (57.5%) with AKI presented in postpartum period, 14/40 (35%) developed AKI in antenatal period, and 3/40 (7.5%) were postabortal. AKI was attributable mostly to sepsis in 11/40 (27.5%) and PPH in 5/40 (12.5%). Hypertension and its complications causing AKI included eclampsia in 5/40 (12.5%) followed by 3/40 (7.5%) as HELLP syndrome and abruption placentae in 2/40(5%) patients. Three patients each (7.5%) had AFLP, TMA, and HEV as the cause of AKI. Renal replacement therapy in the form of hemodialysis was the treatment in majority of them (28 (70%)). After the acute event, 25 (62.5%) had complete recovery of their renal functions at 3 months follow up. Maternal mortality was seen in 25% (n=10) of the study patients. Conclusion: Timely initiation of RRT in patients with AKI associated with pregnancy has a good maternal outcome in the form of complete recovery of renal functions in 62.5% (25/40) of patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AKI" title="AKI">AKI</a>, <a href="https://publications.waset.org/abstracts/search?q=dialysis" title=" dialysis"> dialysis</a>, <a href="https://publications.waset.org/abstracts/search?q=hypertension" title=" hypertension"> hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=sepsis" title=" sepsis"> sepsis</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20parameters" title=" renal parameters"> renal parameters</a> </p> <a href="https://publications.waset.org/abstracts/83127/spectrum-of-acute-kidney-injury-in-obstetrics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83127.pdf" target="_blank" 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