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Jun 2009, 10:55</dd> <dd class="profile-custom-field profile-plz"><strong>Postcode:</strong> 70599</dd> <dd class="profile-custom-field profile-land"><strong>Country:</strong> Germany</dd> </dl> <div class="postbody"> <div id="post_content670"> <h3 class="first"><a href="#p670">Jakobskreuzkraut nicht nur für Tiere gefährlich!</a></h3> <ul class="post-buttons"> <li> <a href="/app.php/post/670/report?sid=209aa89229f794202c696d3f9d1a0e4d" title="Diesen Beitrag melden" class="button button-icon-only"> <i class="icon fa-exclamation fa-fw" aria-hidden="true"></i><span class="sr-only">Diesen Beitrag melden</span> </a> </li> <li> <a href="./../posting.php?mode=quote&amp;p=670&amp;sid=209aa89229f794202c696d3f9d1a0e4d" title="Mit Zitat antworten" class="button button-icon-only"> <i class="icon fa-quote-left fa-fw" aria-hidden="true"></i><span class="sr-only">Zitat</span> </a> </li> </ul> <p class="author"> <a class="unread" href="./../ernaehrung-gesundheit-f166/jakobskreuzkraut-nicht-nur-fuer-tiere-gefaehrlich-t255.html?sid=209aa89229f794202c696d3f9d1a0e4d#p670" title="Beitrag"> <i class="icon fa-file fa-fw icon-lightgray icon-md" aria-hidden="true"></i><span class="sr-only">Beitrag</span> </a> <span class="responsive-hide">von <strong><a href="./../memberlist.php?mode=viewprofile&amp;u=180&amp;sid=209aa89229f794202c696d3f9d1a0e4d" class="username">Leserbrief</a></strong> &raquo; </span>Do 6. Aug 2009, 11:21 </p> <div class="content">Im letzten Herbst wurden in den Niederlanden toxische PA in Honig nachgewiesen. Jetzt liegen erste erschreckende Ergebnisse für Deutschland vor. Im Honig wurde auch die PA vom Jakobskreuzkraut gefunden!!!!! <br> <br> Es wurden Verdachtsproben durch Pollenanalyse sowie 126 Zufallsproben untersucht. Bei den Verdachtsproben konnten nur 4 Proben bestehen; in nahezu der Hälfte der Zufallsproben konnten PA-Gehalte bis zu 250 Mikrogramm / kg nachgewiesen werden.<br> <br> Hinweis: Der Gesetzgeber hat im Stufenplan zur Abwehr von Arzneimittelrisiken 1992 festgelegt, dass Pflanzen und Zubereitungen hieraus nur in den Handel gebracht werden dürfen, wenn sichergestellt ist, dass die tägliche maximale Aufnahme an toxischen PA unter 1 Mikrogramm liegt (BAnz. Nr.: 111, S. 4805 vom 17.6.1992)<br> <br> Eine Humanintoxikation ist grundsätzlich auf zwei Arten möglich (Auszug Dr. Wiedenfeld, Pharmazeutischen Institut Bonn): <br> <br> <strong class="text-strong">1. Direkte Intoxikation </strong><br> <br> 1.1.: orale Aufnahme von Pflanzenmaterial, welches toxische PA enthält. Dies betrifft vordergründig Heilpflanzen, die diese Stoffe enthalten. Beispiele: Huflattich, Beinwell, Borretsch, Fuchs-Kreuzkraut, Goldenes Kreuzkraut. Der medizinische Einsatz dieser Pflanzen ist durch den Erlass des BfArM beschränkt (Stufenplan zur Abwehr von Arzneimittelrisiken, BAnz. Nr.: 111, S. 4805 vom 17.6.1992). <br> <br> Wir haben kürzlich zwei Fälle untersucht, in denen Neugeborene nach einem Tag an akutem Leberversagen gestorben sind. Histologisch wurde VOD festgestellt. Wir konnten die PA-Metabolite in der Leber nachweisen. Die Intoxikation erfolgte durch den täglichen Verzehr eines Pflanzentees mit PA-haltigem Pflanzenmaterial der Mutter über den gesamten Zeitraum der Schwangerschaft. Die aufgenommene Menge an PA war nicht hoch genug, um die Leber der Mutter akut zu schädigen (siehe: Detoxifizierungsmechanismus), dagegen trat eine irreversible Schädigung der wesentlich empfindlicher reagierenden fetalen Leber ein. <br> <br> 1.2.: Kontamination von Lebensmittel, in erster Linie Getreide. Beispiele: endemische Vergiftungsfälle in Indien, Afghanistan, ehemalige UDSSR. In allen Fällen handelte es sich um Brot, das aus Getreide zubereitet war, welches mit PA-haltigem Pflanzenmaterial verunreinigt war. Die Folge: Tausende von Todesfällen. Diese Gefahr besteht in Europa (noch) nicht, da die "Verunreinigung" von Getreidefeldern mit solchen Pflanzen bislang vernachlässigbar ist.<br> <br> 2. Indirekte Intoxikation über die Nahrungsmittelkette <br> <br> 2.1. Milch: der Übergang von toxischen PA in Milch ist vielfach beschrieben. In Jamaika wurden 1989 mehrere Fälle von VOD bei Kleinkindern auf den Verzehr von PA-haltiger Milch zurückgeführt. In Deutschland und Österreich sind acht Fälle beschrieben, in denen der Verdacht bestand, dass über die Muttermilch eine Intoxikation stattgefunden hat. <br> <br> 2.2. Honig: PA-haltige Honigproben wurden bereits häufiger festgestellt. Besonders in Großbritannien sind bis zu 3,9 mg/kg PA in Honig nachgewiesen worden; als pflanzliche Quelle wurde hier Jakobskreuzkraut ermittelt. Vergleichbare Mengen wurden in anderen Proben ermittelt (bis zu 1 mg/kg stammend von Frühlingskreuzkraut; bis 0,1 mg/kg aus alpinen Kreuzkräutern). Alle diese Mengen liegen deutlich oberhalb der Menge, die im Stufenplan zur Abwehr von Arzneimittelrisiken als zulässig angesehen werden. <br> <br> 2.3. Eier: einen möglichen Übergang von PA in Eier wurde nachgewiesen. Eier von Geflügel, welches Futter verzehrte, das mit Samen von Heliotropium europaeum versetzt war, zeigten Gehalte bis zu 9,7 Mikrogramm toxischer PA. Auch dies überschreitet den als toxische Grenze angesehenen Wert deutlich. <br> <br> 2.4. Fleisch: einen Übergang der PA in Fleisch wurde bisher nicht bestätigt. Ausnahme natürlich Organe (Leber!).<br> <br> <br> H. Wieters</div> </div> </div> </div> <div class="back2top"> <a href="#top" class="top" title="Nach oben"> <i class="icon fa-chevron-circle-up fa-fw icon-gray" aria-hidden="true"></i> <span class="sr-only">Nach oben</span> </a> </div> </div> <div id="p694" class="post has-profile bg1"> <div class="inner"> <dl class="postprofile" id="profile694"> <dt class="no-profile-rank no-avatar"> <div class="avatar-container"> </div> <a href="./../memberlist.php?mode=viewprofile&amp;u=72&amp;sid=209aa89229f794202c696d3f9d1a0e4d" class="username">Nuzzle</a> </dt> <dd class="profile-posts"><strong>Beiträge:</strong> <a href="./../search.php?author_id=72&amp;sr=posts&amp;sid=209aa89229f794202c696d3f9d1a0e4d">194</a></dd> <dd class="profile-joined"><strong>Registriert:</strong> Mo 27. Apr 2009, 14:49</dd> <dd class="profile-custom-field profile-plz"><strong>Postcode:</strong> 24944</dd> <dd class="profile-custom-field profile-land"><strong>Country:</strong> Germany</dd> </dl> <div class="postbody"> <div id="post_content694"> <h3 ><a href="#p694">Re: Jakobskreuzkraut nicht nur für Tiere gefährlich!</a></h3> <ul class="post-buttons"> <li> <a href="/app.php/post/694/report?sid=209aa89229f794202c696d3f9d1a0e4d" title="Diesen Beitrag melden" class="button button-icon-only"> <i class="icon fa-exclamation fa-fw" aria-hidden="true"></i><span class="sr-only">Diesen Beitrag melden</span> </a> </li> <li> <a href="./../posting.php?mode=quote&amp;p=694&amp;sid=209aa89229f794202c696d3f9d1a0e4d" title="Mit Zitat antworten" class="button button-icon-only"> <i class="icon fa-quote-left fa-fw" aria-hidden="true"></i><span class="sr-only">Zitat</span> </a> </li> </ul> <p class="author"> <a class="unread" href="./../ernaehrung-gesundheit-f166/jakobskreuzkraut-nicht-nur-fuer-tiere-gefaehrlich-t255.html?sid=209aa89229f794202c696d3f9d1a0e4d#p694" title="Beitrag"> <i class="icon fa-file fa-fw icon-lightgray icon-md" aria-hidden="true"></i><span class="sr-only">Beitrag</span> </a> <span class="responsive-hide">von <strong><a href="./../memberlist.php?mode=viewprofile&amp;u=72&amp;sid=209aa89229f794202c696d3f9d1a0e4d" class="username">Nuzzle</a></strong> &raquo; </span>Sa 15. Aug 2009, 04:24 </p> <div class="content">Der NABU rief kürzlich zu mehr Gelassenheit beim Jakobs-Kreuzkraut auf: <a href="http://nrw.nabu.de/tiereundpflanzen/pflanzen/jakobskreuzkraut/index.html" class="postlink">http://nrw.nabu.de/tiereundpflanzen/pfl ... index.html</a><br> da von der bitter schmeckenden Pflanze für Menschen s.E. keine unmittelbare Gefahr ausgehe. Die Landwirtschaftskammer NRW scheint das wiederum etwas anders zu sehen: <a href="http://www.landwirtschaftskammer.de/landwirtschaft/ackerbau/gruenland/jakobskreuzkraut.htm" class="postlink">http://www.landwirtschaftskammer.de/lan ... zkraut.htm</a></div> </div> </div> </div> <div class="back2top"> <a href="#top" class="top" title="Nach oben"> <i class="icon fa-chevron-circle-up fa-fw icon-gray" aria-hidden="true"></i> <span class="sr-only">Nach oben</span> </a> </div> </div> <div class="action-bar bar-bottom"> <a href="./../posting.php?mode=reply&amp;t=255&amp;sid=209aa89229f794202c696d3f9d1a0e4d" class="button" title="Antwort erstellen"> <span>Antworten</span> <i class="icon fa-reply fa-fw" aria-hidden="true"></i> </a> <div class="dropdown-container dropdown-button-control topic-tools"> <span title="Themen-Optionen" class="button button-secondary dropdown-trigger dropdown-select"> <i class="icon fa-wrench fa-fw" aria-hidden="true"></i> <span class="caret"><i class="icon fa-sort-down fa-fw" aria-hidden="true"></i></span> </span> <div class="dropdown"> <div class="pointer"><div class="pointer-inner"></div></div> <ul class="dropdown-contents"> <li> <a href="./../viewtopic.php?t=255&amp;sid=209aa89229f794202c696d3f9d1a0e4d&amp;view=print" title="Druckansicht" accesskey="p"> <i class="icon fa-print fa-fw" aria-hidden="true"></i><span>Druckansicht</span> </a> </li> </ul> </div> </div> <form method="post" action="./../viewtopic.php?t=255&amp;sid=209aa89229f794202c696d3f9d1a0e4d"> <div class="dropdown-container dropdown-container-left dropdown-button-control sort-tools"> <span title="Anzeige- und Sortierungs-Einstellungen" class="button button-secondary dropdown-trigger dropdown-select"> <i class="icon fa-sort-amount-asc fa-fw" aria-hidden="true"></i> <span class="caret"><i class="icon fa-sort-down fa-fw" aria-hidden="true"></i></span> </span> <div class="dropdown hidden"> <div class="pointer"><div class="pointer-inner"></div></div> <div class="dropdown-contents"> <fieldset class="display-options"> <label>Anzeigen: <select name="st" id="st"><option value="0" selected="selected">Alle Beiträge</option><option value="1">1 Tag</option><option value="7">7 Tage</option><option value="14">2 Wochen</option><option value="30">1 Monat</option><option value="90">3 Monate</option><option value="180">6 Monate</option><option value="365">1 Jahr</option></select></label> <label>Sortiere nach: <select name="sk" id="sk"><option value="a">Autor</option><option value="t" selected="selected">Erstellungsdatum</option><option value="s">Betreff</option></select></label> <label>Richtung: <select name="sd" id="sd"><option value="a" selected="selected">Aufsteigend</option><option value="d">Absteigend</option></select></label> <hr class="dashed" /> <input type="submit" class="button2" name="sort" value="Los" /> </fieldset> </div> </div> </div> </form> <div class="pagination"> 2 Beiträge &bull; 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