Gene Therapy Legislation in Czech Republic

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While the manufacturing and application of the medicinal product to the patient is in principle regulated under the contained use rules, the deliberate release framework applies if there is a possibility of shedding of the GMM into the environment after the application.</p> <p>The applications to seek authorization under the clinical trials framework and under the GMO framework can be submitted in parallel (i.e. the sponsor should apply for GMO authorization but does not need to wait for the GMO authorization before submitting the clinical trial application).</p> <p>Additional information can be found at: <br> - <a href="https://www.mzp.cz/Biosafety/pdf/Information_for_notifiers_about_clinical_trials.pdf" target="blank">https://www.mzp.cz/Biosafety/pdf/Information_for_notifiers_about_clinical_trials.pdf</a><br> - <a href="https://www.sukl.eu/medicines/clinical-trial-on-pharmaceuticals" target="blank">https://www.sukl.eu/medicines/clinical-trial-on-pharmaceuticals</a> </p> <p><b>Application forms to seek authorisation for the GMO aspects</b><br> Application forms can be found at: <a href="https://www.mzp.cz/cz/formulare_metodicke_pokyny_gmo" target="blank">https://www.mzp.cz/cz/formulare_metodicke_pokyny_gmo</a></p> <p><b>Public consultation</b><br> The Ministry of the Environment makes a summary of the notification for deliberate release, which is made published on its website. The Ministry also ensures its publication by the relevant municipality and regional authorities, according to the intended release location. After the publication, there is a period of 30 days for public comments. </p> <hr><p><b>National authorities involved</b></p> <p><i>Authorization of clinical trials:</i><br> State Institute for Drug Control<br> Srobarova 49, 130 00, Prague 3, Czech Republic<br> Dr Alice Nemcova, Head of Clinical Trials and Unregistered Medicinal Products Section<br> e-mail: alice.nemcova@sukl.cz /p> <p> <i>Authorisation of GMO aspects:</i><br> Ministry of the Environment<br> Vrsovicka 65, 100 00 Prague 10, Czech Republic<br> Ms Zuzana Doubkova, Head of GMO Unit<br> e-mail: <joomla-hidden-mail is-link="1" is-email="1" first="enV6YW5hLmRvdWJrb3Zh" last="bXpwLmN6" text="enV6YW5hLmRvdWJrb3ZhQG16cC5jeg==" base="" >This email address is being protected from spambots. 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Gene Therapy Legislation in Czech Republic