Baishideng Publishing Group

<!DOCTYPE html> <html> <head> <meta name="viewport" content="width=device-width" /> <title>Baishideng Publishing Group</title> <link href="/Content/css?v=rb26yubA8f-T2hXbl5_Lk0hga4CBdoXSmzfqDaG2x281" rel="stylesheet"/> <script src="/bundles/modernizr?v=wBEWDufH_8Md-Pbioxomt90vm6tJN2Pyy9u9zHtWsPo1"></script> <script src="/bundles/jquery?v=FVs3ACwOLIVInrAl5sdzR2jrCDmVOWFbZMY6g6Q0ulE1"></script> <script type="text/javascript"> $(function () { $("#statisticFrame").attr("src", "/ManuscriptChart"); }); $(function () { var iFrames = $("#statisticFrame"); iFrames.load(function () { this.style.height = (this.contentWindow.document.body.offsetHeight - 30) + 'px'; }); }); </script> </head> <body> <div class="siteBody"> <div class="index-main cl"> <div class="left fl"> <div class="mnavbar"> <div> <a href="https://www.f6publishing.com/" target="_blank">Submit a Manuscript</a> </div> </div> <div class="mnavbox"> <div class="navselect"> <select id="main_list_1"> <option value="0|https://www.wjgnet.com/bpg/gerinfo/242">Article Processing Charge</option> <option value="1|https://www.wjgnet.com/bpg/GerList/1">General Information</option> <option value="2|https://www.wjgnet.com/bpg/gerinfo/204">Guidelines for Authors</option> <option value="3|https://www.wjgnet.com/bpg/gerinfo/316">Guidelines for Manuscript Decision</option> <option value="4|https://www.wjgnet.com/bpg/GerInfo/287">Guidelines for Manuscript Type and Related Ethics Documents</option> <option value="5|https://www.wjgnet.com/bpg/gerinfo/240">Language Editing Process for Manuscripts Submitted by Non-Native Speakers of English</option> <option value="6|https://www.wjgnet.com/bpg/gerinfo/241">Peer-Review Process</option> <option value="7|https://www.wjgnet.com/bpg/gerinfo/288">Publication Ethics</option> <option value="8|http://www.wjgnet.com/bpg/GerInfo/239">Steps for Submitting Manuscripts</option> <option value="9|https://www.f6publishing.com">Submit a Manuscript</option> <option value="10|https://www.wjgnet.com/1009-3079/Nav/458">世界华人消化杂志手稿出版费缴纳指南</option> <option value="11|https://www.baishideng.com">世界华人消化杂志在线投稿</option> <option value="12|https://www.wjgnet.com/1009-3079/Nav/36">世界华人消化杂志作者投稿指南</option> </select> </div> <div class="gobtn"> <button type="button" class="btn btn-primary" onclick="nav('main_list_1');">Go</button> </div> </div> <div class="mnavbar"> <div> <a href="https://www.f6publishing.com" target="_blank">F6Publishing</a> </div> </div> <div class="mnavbox"> <a href="https://www.f6publishing.com" target="_blank"> <img style="width:100%;" src="https://bsdwebstorage.blob.core.windows.net/journalqrcodes/e6950aac-b0ce-4ede-ba7a-3456aff9351a.png" /> </a> </div> <div class="mnavbar"> <div> Publisher Login </div> </div> <div class="mnavbox"> <a href="https://admin.f6publishing.com/" target="_blank"> <img style="width:100%;margin-bottom:5px;" src="https://bsdwebstorage.blob.core.windows.net/journalqrcodes/2b965753-d859-4f2b-8521-c5f4c18e2383.png" /> </a> <a href="https://referencecitationanalysis.com/forms/admin/login" target="_blank"> <img style="width:100%;" src="https://bsdwebstorage.blob.core.windows.net/journalqrcodes/34593440-275e-4989-afdb-4de6008f6b0e.png" /> </a> </div> <div class="mnavbar"> <div> Manuscript Statistics </div> </div> <div class="mnavbox"> <div class="framepart cl"> <iframe id="statisticFrame" name="statisticFrame" src="" height="790" marginheight="0" marginwidth="0" width="100%" scrolling="no" frameborder="0"></iframe> </div> </div> <div class="mnavbar"> <div> <a href="https://www.f6publishing.com/ArticlesInPress" target="_blank">Articles In Press</a> </div> </div> <div class="mnavbox"> <div class="articlelist cl"> <div class="articleitem cl"> <div class="num fl"> 1 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=98552" target="_blank"> Lu DF, Zheng R, Li A, Zhang JQ. Efficacy of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists on proteinuria and weight in a diabetes cohort. <i>World J Diabetes</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 4 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 2 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101501" target="_blank"> Zhang LS, Yu P, Yao F, Lu ZQ, Li XM, Chen H. Insulin autoantibodies, D-dimer and microalbuminuria: A cross-sectional, case-control study of type 2 diabetes. <i>World J Diabetes</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 3 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 3 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=97271" target="_blank"> Li Y, Wang B, Xu MT, Wang YY, Liu WQ, Fu SJ, Li BW, Ling H, Liu XT, Zhang XY, Li AL, Zhang X, Liu MM. Interdisciplinary perspectives on diabetes and microcirculatory dysfunction: A global bibliometric analysis. <i>World J Diabetes</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 2 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 4 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101128" target="_blank"> Chai M, Zhang CY, Chen S, Xu DH. Application of autophagy in mesenchymal stem cells. <i>World J Stem Cells</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 4 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 5 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=102131" target="_blank"> Okpete UE, Byeon H. Brain-derived neurotrophic factor alterations and cognitive decline in schizophrenia: Implications for early intervention. <i>World J Psychiatry</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 5 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 6 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=102003" target="_blank"> Virches A, Claudino MB, Miyazaki MC, Miyazaki ET, Silva RF, Silva RC, Farias HB, Domingos NA, Santos Jr R, Fucuta PS. Burden, stress and depression in caregivers of cirrhosis patients before and after liver transplantation. <i>World J Transplant</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 13 | Download: 1 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 7 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101861" target="_blank"> Gonzalez FM. Hepatorenal syndrome: Paving a pathway from a fatal condition to an opportunity to preserve kidney function. <i>World J Nephrol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 3 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 8 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101647" target="_blank"> Anaya-Prado R, Canseco-Villegas AI, Anaya-Fernández R, Anaya-Fernandez MM, Guerrero-Palomera MA, Guerrero-Palomera C, Garcia-Ramirez IF, Gonzalez-Martinez D, Azcona-Ramírez CC, Garcia-Perez C, Lizarraga-Valencia AL, Hernandez-Zepeda A, Palomares-Covarrubias JF, Blackaller-Medina JH, Soto-Hintze J, Velarde-Castillo MC, Cruz-Melendrez DA. Role of nitric oxide in cerebral ischemia/reperfusion injury: A biomolecular overview. <i>World J Clin Cases</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 7 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 9 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101704" target="_blank"> Cano Contreras AD, Del Rocío Francisco M, Vargas Basurto JL, Gonzalez-Gomez KD, Amieva-Balmori M, Roesch Dietlen F, Remes-Troche JM. Effect of alpha-lipoic acid and Silybum marianum supplementation with a Mediterranean diet on metabolic dysfunction-associated steatosis. <i>World J Hepatol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 4 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 10 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=96230" target="_blank"> Wang F, Mu HF, Wang C, Tang Y, Si MY, Peng J. LncRNA PCAT6 promotes progression and metastasis of colonic neuroendocrine carcinoma via MAPK pathway. <i>World J Gastrointest Oncol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 3 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 11 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101686" target="_blank"> Chahal S, Patial V. Therapeutic potential of kakkatin derivatives against hepatocellular carcinoma. <i>World J Clin Oncol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 2 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 12 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101639" target="_blank"> Nagesh VK, Pulipaka SP, Bhuju R, Martinez E, Badam S, Nageswaran GA, Tran HHV, Elias D, Mansour C, Musalli J, Bhattarai S, Shobana LS, Sethi T, Sethi R, Nikum N, Trivedi C, Jarri A, Westman C, Ahmed N, Philip S, Weissman S, Weinberger J, Bangolo AI. Management of gastrointestinal bleed in the intensive care setting, an updated literature review. <i>World J Crit Care Med</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 64 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 13 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101177" target="_blank"> Huang R, Cui J. Impact of Linggui Zhugan decoction on microwave ablation outcomes and recurrence in liver cancer. <i>World J Gastrointest Oncol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 2 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 14 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101630" target="_blank"> Soni J, Pathak N, Gharia M, Aswal D, Parikh J, Sharma P, Mishra A, Lalan D, Maheshwari T. Effectiveness of RESET care program: A real-world-evidence on managing non-alcoholic fatty liver disease through digital health interventions. <i>World J Hepatol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 18 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 15 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101195" target="_blank"> Perazza F, Ravaioli F. Small bites, big impact: The importance of evening snacks in patients with advanced chronic liver disease. <i>World J Hepatol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 4 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 16 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=100954" target="_blank"> Guo TH, Hong SW, Zhu WJ, Hui YF, Qiu WL, Wu Y, Li X, Ke F, Li L, Cheng H. Anti-programmed death-1 immunotherapy-promising treatment for metastatic colorectal cancer: A case report. <i>World J Gastrointest Oncol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 5 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 17 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101153" target="_blank"> Li YL, Chen EG, Ren BB. Umbilical cord-derived mesenchymal stromal cells: Promising therapy for heart failure. <i>World J Cardiol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 5 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 18 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=100968" target="_blank"> Majeed AA, Butt AS. Hepatitis B virus infection and metabolic dysfunction associated steatotic liver disease: Rising pandemic with complex interaction. <i>World J Hepatol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 3 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 19 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=101888" target="_blank"> Krishnan A. Radiotherapy dosage: A neural network approach for uninvolved liver dose in stereotactic body radiation therapy for liver cancer. <i>World J Gastrointest Oncol</i> 2025; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 4 | Download: 0 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 20 </div> <div class="item fl"> <div class="title"> <a href="https://www.f6publishing.com/ArticleInPressPubDetail?id=102151" target="_blank"> Zhang Y. Enhancing rectal cancer liver metastasis prediction: Magnetic resonance imaging-based radiomics, bias mitigation, and regulatory considerations. <i>World J Gastrointest Oncol</i> 2024; In press </a> </div> <div class="count"> 2024-12-02 | Browse: 2 | Download: 0 </div> </div> </div> <div class="more"> <span>397 items</span>  <a href="https://www.f6publishing.com/ArticlesInPress" target="_blank">Read more >></a> </div> </div> </div> <div class="mnavbar"> <div> <a href="https://www.f6publishing.com/AuthorReviews" target="_blank">Author Reviews</a> </div> </div> <div class="mnavbox"> <div class="articlelist cl"> <div class="articleitem cl"> <div class="num fl"> 1 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2222-0682/full/v15/i2/98513.htm" class="author-comment" target="_blank"> "The process for the submission process from initial submission to the follow up has been smooth. The editors has been in constant ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2222-0682/full/v15/i2/98513.htm" target="_blank" class="author-comment"> "The process for the submission process from initial submission to the follow up has been smooth. The editors has been in constant communication throughout the process. The process has changed over the time and some redundant things have been removed. Still the coi going to the authors has been hit and miss as many times they end up in the spam folders. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Grewal H, Dhillon G, Buddhavarapu V, Verma RK, Munjal RS, Sharma P, Sidhu G, Kashyap R, Surani S. Strategic insights of telehealth platforms and strengths, weaknesses, opportunities, and threats analysis of Amazon's clinical endeavors. <em>World J Methodol</em> 2025; 15(2): 98513 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 2 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2307-8960/full/v13/i7/97847.htm" class="author-comment" target="_blank"> "The authors have invested significant time and effort to complete this article. It has not been published elsewhere, and we will not ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2307-8960/full/v13/i7/97847.htm" target="_blank" class="author-comment"> "The authors have invested significant time and effort to complete this article. It has not been published elsewhere, and we will not consider submission to any other journal while it is under review by your journal. We would like to extend our heartfelt gratitude to the editorial team for their expert guidance and to the reviewers for their diligent efforts. Their professional insights and thorough evaluations have greatly improved the quality and clarity of our manuscript on the rehabilitation of pediatric sensorineural hearing loss.We also greatly appreciate the editorial team's assistance with the article submission process. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Zhang L, Huang PJ, Deng X, Tang J, Zhai Y, Wang T. Physical rehabilitation for sensorineural hearing loss in childhood: Progress and challenges. <em>World J Clin Cases</em> 2025; 13(7): 97847 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 3 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2222-0682/full/v15/i2/99300.htm" class="author-comment" target="_blank"> "Baishideng provides us the best publication experience. Thanks to the commendable team and the IT platform created for publication. ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2222-0682/full/v15/i2/99300.htm" target="_blank" class="author-comment"> "Baishideng provides us the best publication experience. Thanks to the commendable team and the IT platform created for publication. The entire process is transparent and fair and even if some manuscripts are rejected, the authors can learn for future improvements. The insights provided by the reviews are extremely relevant to improve the manuscript quality. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Anand R, Nag DS, Patel R, Sharma P, Uppalapati VK, Singh UK. Comparative efficacy of hyperbaric bupivacaine <i>vs</i> hyperbaric ropivacaine in spinal anesthesia for cesarean section: A meta-analysis. <em>World J Methodol</em> 2025; 15(2): 99300 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 4 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3230/full/v15/i1/97598.htm" class="author-comment" target="_blank"> "I strongly feel that too much emphasis is placed on documentation other than the manuscript itself during the submission process. ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3230/full/v15/i1/97598.htm" target="_blank" class="author-comment"> "I strongly feel that too much emphasis is placed on documentation other than the manuscript itself during the submission process. In our case, the reviewer had said that english was acceptable, yet we were pushed to get help and other stuff like that. This type of requirements discourages authors because they spend more time on such activities rather than the actual manuscript. The help desk provided no help, they promptly responded to the query but no solution. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Khan T, Ahmad N, Iqbal Q, Hassan M, Asnath L, Khan N, Shakeel S. Comparative study of living donor kidney transplants: Right <i>vs</i> left. <em>World J Transplant</em> 2025; 15(1): 97598 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 5 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/99496.htm" class="author-comment" target="_blank"> "There was a lot of delays in the peer review process and publication. The supplementary table is not available online for easy access. ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/99496.htm" target="_blank" class="author-comment"> "There was a lot of delays in the peer review process and publication. The supplementary table is not available online for easy access. The AI-based system of peer reviewer recruitment is useless delaying the whole publication process. Although I suggested adding the table 2 with the manuscript, the managing editor was so particular that the table has to be supplementary but it is not appropriately cited in the online version of the paper I can see. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Mondal S, Pappachan JM. Current perspectives and the future of disease-modifying therapies in type 1 diabetes. <em>World J Diabetes</em> 2025; 16(1): 99496 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 6 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3647.htm" class="author-comment" target="_blank"> "Thank the editors and reviewers for their contributions to our manuscript, which have a great help in improving manuscript. We hope ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3647.htm" target="_blank" class="author-comment"> "Thank the editors and reviewers for their contributions to our manuscript, which have a great help in improving manuscript. We hope to have the opportunity to publish more our work in this journal,to improve the quality of our medical service and our teaching. To showcase our results on this platform and also learn from the excellent results of other peers. To improve the technical, teaching, training and other aspects of gastrointestinal surgery " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Feng YY, Jin Y. Current status and future of hepato–pancreatico–biliary surgery fellowship training in China. <em>World J Gastrointest Surg</em> 2024; 16(12): 3647-3649 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 7 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/94846.htm" class="author-comment" target="_blank"> "The editorial office of your journal demonstrates exceptional efficiency and professionalism, providing an outstanding experience ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/94846.htm" target="_blank" class="author-comment"> "The editorial office of your journal demonstrates exceptional efficiency and professionalism, providing an outstanding experience for authors. From the initial review to expert evaluation and final revision suggestions, the entire process is transparent and well-structured, ensuring a fair and high-quality platform for presenting research findings. The editorial office bridges authors and readers with a platform that combines academic excellence with exceptional service quality, making a substantial contribution to advancements in the field. I hope your journal continues its exemplary work and continues to attract high-quality research to further drive academic progress! " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Liu SQ, Wang D, Tang CC. Association between age at diagnosis of diabetes and ocular disease: Insights from a recent article. <em>World J Diabetes</em> 2025; 16(1): 94846 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 8 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/96032.htm" class="author-comment" target="_blank"> "Dear Editorial Team, I would like to express my sincere gratitude to the editorial team for the thorough external review, acceptance, ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/96032.htm" target="_blank" class="author-comment"> "Dear Editorial Team, I would like to express my sincere gratitude to the editorial team for the thorough external review, acceptance, and editing of my manuscript. I am honored that my research has been selected for publication in your esteemed journal. I deeply appreciate the valuable feedback from the reviewers, which greatly enhanced the quality of the paper. Special thanks to the editorial team for their meticulous work in editing and formatting, ensuring the final version was polished and ready for publication. I look forward to future collaborations with your journal. Best regards, Kuo Gao " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Zhang FS, Li HJ, Yu X, Song YP, Ren YF, Qian XZ, Liu JL, Li WX, Huang YR, Gao K. Global trends and hotspots of type 2 diabetes in children and adolescents: A bibliometric study and visualization analysis. <em>World J Diabetes</em> 2025; 16(1): 96032 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 9 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/95209.htm" class="author-comment" target="_blank"> "I am generally satisfied with the journal's submission and publication process. The online submission system was user-friendly, and ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/95209.htm" target="_blank" class="author-comment"> "I am generally satisfied with the journal's submission and publication process. The online submission system was user-friendly, and the peer review process was thorough and efficient. The editorial team provided valuable feedback, which significantly improved the quality of the manuscript. Overall, I am pleased with the experience and look forward to future collaborations. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Yang N, Lv L, Han SM, He LY, Li ZY, Yang YC, Ping F, Xu LL, Li W, Zhang HB, Li YX. Efficacy, safety and treatment satisfaction of transition to a regimen of insulin degludec/aspart: A pilot study. <em>World J Diabetes</em> 2025; 16(1): 95209 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 10 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2307-8960/full/v13/i7/101214.htm" class="author-comment" target="_blank"> "The entire process from initial review and revision to final acceptance is very professional and organized, and the online submission ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2307-8960/full/v13/i7/101214.htm" target="_blank" class="author-comment"> "The entire process from initial review and revision to final acceptance is very professional and organized, and the online submission system is relatively easy to operate. The editorial committee is very professional and responsible in handling manuscripts, and the peer review report is fair, which greatly helps with manuscript revisions. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Wang YL, Li J. Insulin-induced severe thyrotoxic periodic paralysis: A case report. <em>World J Clin Cases</em> 2025; 13(7): 101214 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 11 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3875.htm" class="author-comment" target="_blank"> "I am thoroughly impressed with the entire process of submission, editing, and publication. The editorial team has been exceptional, ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3875.htm" target="_blank" class="author-comment"> "I am thoroughly impressed with the entire process of submission, editing, and publication. The editorial team has been exceptional, offering unwavering assistance and support at every stage. The timeline from submission to publication is impressively efficient, and the editing process, coupled with seamless direct communication with the editors, has been incredibly smooth. Thank you for your outstanding help and dedication! " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Alharbi S, Alturaif N, Mostafa Y, Alfhaid A, Albenmousa A, Alghamdi S. Pulmonary hypertension post-liver transplant: A case report. <em>World J Gastrointest Surg</em> 2024; 16(12): 3875-3880 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 12 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98804.htm" class="author-comment" target="_blank"> "The journal is outstanding and highly indexed, i hope that it is included in the top 10% journals in its field and it is serving the ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98804.htm" target="_blank" class="author-comment"> "The journal is outstanding and highly indexed, i hope that it is included in the top 10% journals in its field and it is serving the scientific community by publishing high-standard articles from reputed authors. Regarding the Editorial Board, they are professional, and their intention is to help authors in their publication, and peer review process is very meticulous. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Mirghani HO. Prediabetes and atrial fibrillation risk stratification, phenotyping, and possible reversal to normoglycemia. <em>World J Diabetes</em> 2025; 16(1): 98804 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 13 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3764.htm" class="author-comment" target="_blank"> "The efficiency with which you handled our submission is highly commendable. From the initial review to the final publication, ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3764.htm" target="_blank" class="author-comment"> "The efficiency with which you handled our submission is highly commendable. From the initial review to the final publication, everything was organized and completed in a timely manner, demonstrating your excellent editorial professionalism. We look forward to the possibility of collaborating with you again in the future. With your excellent editorial support, we are confident that our future research findings can reach a wider audience through this remarkable journal. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Wang XY, Zhao YL, Wen SS, Song XY, Mo L, Xiao ZW. Intraoperative thermostatic nursing and failure mode and effects analysis enhance gastrectomies’ care quality. <em>World J Gastrointest Surg</em> 2024; 16(12): 3764-3771 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 14 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3843.htm" class="author-comment" target="_blank"> "The submission system and review system are both good, with high efficiency and a good overall process experience.The online submission ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3843.htm" target="_blank" class="author-comment"> "The submission system and review system are both good, with high efficiency and a good overall process experience.The online submission system is relatively easy to operate. The editors process manuscripts very quickly and respond promptly. Peer review report for our manuscript is fair and of great help to the manuscript. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Cheng MZ, Luo JH, Li X, Liu FY, Zhou WJ. Zinc pretreatment for protection against intestinal ischemia-reperfusion injury. <em>World J Gastrointest Surg</em> 2024; 16(12): 3843-3856 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 15 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5104.htm" class="author-comment" target="_blank"> "It is an honor to have published our article in the World Journal of Gastroenterology. I am grateful to the editors and the publishing ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5104.htm" target="_blank" class="author-comment"> "It is an honor to have published our article in the World Journal of Gastroenterology. I am grateful to the editors and the publishing system; it is very user-friendly and fast. The feedback from both the peer reviewers and the editors has been extremely valuable. I am satisfied with the rigor applied, the timelines, the platform, and the galley proofs review process. Thank you. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Priego-Parra BA, Remes-Troche JM. Bidirectional relationship between gastrointestinal cancer and depression: The key is in the microbiota-gut-brain axis. <em>World J Gastroenterol</em> 2024; 30(48): 5104-5110 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 16 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3703.htm" class="author-comment" target="_blank"> "Very good experience to submit and publish; the peer review report is of great help; we are satisfied with the editing and publishing ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3703.htm" target="_blank" class="author-comment"> "Very good experience to submit and publish; the peer review report is of great help; we are satisfied with the editing and publishing rules and norms; satisfied with the editing and publishing rules and norms; satisfied with the time spent for peer review; satisfied with the anonymous peer review process; satisfied with the online submission system " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Li JY, Ping L, Lin BZ, Wang ZH, Fang CH, Hua SR, Han XL. Efficacy of multi-color near-infrared fluorescence with indocyanine green: A new imaging strategy and its early experience in laparoscopic cholecystectomy. <em>World J Gastrointest Surg</em> 2024; 16(12): 3703-3709 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 17 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/96098.htm" class="author-comment" target="_blank"> "I would like to extend my sincere thanks to the assistant editor, science editor, peer reviewers, editorial director, journal ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/96098.htm" target="_blank" class="author-comment"> "I would like to extend my sincere thanks to the assistant editor, science editor, peer reviewers, editorial director, journal editor-in-chief, company editor-in-chief, language editor, and production editor for their outstanding efforts. The online submission process for WJV is efficient and user-friendly, while the publication guidelines are well-defined, ensuring a smooth experience. The review cycle met expectations and was completed in a timely manner. The professionalism and attention to detail throughout the publishing process were exemplary, resulting in a smooth and collaborative journey. The peer reviewers provided thorough and objective feedback, and their reports were both detailed and fair. The quality of article editing and typesetting was excellent. WJV maintains a strong reputation for credibility. I appreciate the editorial team's thoroughness and the clear communication at each stage. In the future, I will prioritize submitting to this journal. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Thakur SK, Sinha AK, Sharma SK, Jahan A, Negi DK, Gupta R, Singh S. Prevalence of transfusion transmissible infections among various donor groups: A comparative analysis. <em>World J Virol</em> 2025; 14(1): 96098 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 18 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98798.htm" class="author-comment" target="_blank"> "We are honored to have our manuscript, "Unveiling mitochondrial mysteries: Exploring novel tRNA variants in type 2 diabetes mellitus," ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98798.htm" target="_blank" class="author-comment"> "We are honored to have our manuscript, "Unveiling mitochondrial mysteries: Exploring novel tRNA variants in type 2 diabetes mellitus," published in the World Journal of Diabetes. This publication represents a significant milestone in our research journey, and we deeply appreciate the meticulous efforts of the editorial team, peer reviewers, and all involved in bringing this work to fruition. The peer-review process was both rigorous and constructive, offering valuable insights that strengthened our study. We are particularly impressed by the journal's transparency and commitment to fostering academic dialogue, exemplified by the publication of peer-review reports and reader comments. Furthermore, the editorial and production teams demonstrated exceptional professionalism and efficiency, ensuring a smooth publication process. This reflects the journal’s dedication to maintaining high standards and advancing the field of diabetes research. We hope this work contributes meaningfully to understanding mitochondrial tRNA variants in type 2 diabetes mellitus and sparks further exploration in this area. We encourage readers and fellow researchers to engage with our findings, provide feedback, and collaborate to drive innovation in diabetes research. Thank you once again for this opportunity to share our work with the global scientific community. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Cheng CH, Hao WR, Cheng TH. Unveiling mitochondrial mysteries: Exploring novel tRNA variants in type 2 diabetes mellitus. <em>World J Diabetes</em> 2025; 16(1): 98798 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 19 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i46/4969.htm" class="author-comment" target="_blank"> "It is truly a privilege and an honor to collaborate with such dedicated and professional editors. Each step of the journal publication ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i46/4969.htm" target="_blank" class="author-comment"> "It is truly a privilege and an honor to collaborate with such dedicated and professional editors. Each step of the journal publication process was not only seamless but also meticulously structured to ensure the highest standards of quality. Their expertise and guidance were invaluable in refining and enhancing the final publication to its best potential. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Hasnaoui A, Trigui R, Giuffrida M. Gut microbiota and mesenteric adipose tissue interactions in shaping phenotypes and treatment strategies for Crohn’s disease. <em>World J Gastroenterol</em> 2024; 30(46): 4969-4976 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 20 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i12/1395.htm" class="author-comment" target="_blank"> "Thank you very much for the efforts of the editors and review experts. This is a very satisfactory submission, the review and ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i12/1395.htm" target="_blank" class="author-comment"> "Thank you very much for the efforts of the editors and review experts. This is a very satisfactory submission, the review and publication speed is fast, the review experts are professional, the editor is very responsible, and it is a very good submission. Next time, I will give priority to the submission journal. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Li HD, Liu YN, Wu S, Quan XF, Wang XY, Xiang TD, Li SM, Xu L, Wang T, Wang H, Zheng X. Influence of nonalcoholic fatty liver disease on the therapeutic effect of nucleoside (acid) analogs for hepatitis B virus. <em>World J Hepatol</em> 2024; 16(12): 1395-1406 </div> </div> </div> <div class="more"> <span>17169 items</span>  <a href="https://www.f6publishing.com/AuthorReviews" target="_blank">Read more >></a> </div> </div> </div> <div class="mnavbar"> <div> <a href="https://www.f6publishing.com/ArticleQualityTrackings" target="_blank">Article Quality Tracking-Peer-Review</a> </div> </div> <div class="mnavbox"> <div class="articlelist cl"> <div class="articleitem cl"> <div class="num fl"> 1 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i12/1417.htm" class="author-comment" target="_blank"> "There is ambiguity in the diagnosis of Amebic and Hydatid cyst abscess in the method section. Was serum antibody against the parasite ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i12/1417.htm" target="_blank" class="author-comment"> "There is ambiguity in the diagnosis of Amebic and Hydatid cyst abscess in the method section. Was serum antibody against the parasite applied for diagnosis? The sensitivity of serum antibody for the detection of Hydatid cyst and amebic liver abscess is not high. Was the diagnosis of Amebic liver disease based on the aspiration of typical chocolate fluid? Was the diagnosis of Hydatid cyst abscess documented based on the finding of typical hydatid cysts in the liver/lung imaging?" </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Pillay K, Khan ZA, Nweke EE, Omoshoro-Jones J. Clinicopathological presentation of liver abscesses and hydatid liver disease from two South African tertiary hospitals. <em>World J Hepatol</em> 2024; 16(12): 1417-1428 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 2 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i12/1377.htm" class="author-comment" target="_blank"> "MASLD is the leading cause of cirrhosis worldwide. An important aspect of the disease is cardiometabolic concerns. The major morbidity ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i12/1377.htm" target="_blank" class="author-comment"> "MASLD is the leading cause of cirrhosis worldwide. An important aspect of the disease is cardiometabolic concerns. The major morbidity in the mentioned patients are cardiac and cerebrovascular insults. Therefore, the intime collaboration of cardiologists to screen for cardiac insults is necessary to reduce the cardiac related mortality and morbidity in these patients." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Protopapas AA, Tsankof A, Papagiouvanni I, Kaiafa G, Skoura L, Savopoulos C, Goulis I. Outpatient management after hospitalisation for acute decompensation of cirrhosis: A practical guide. <em>World J Hepatol</em> 2024; 16(12): 1377-1394 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 3 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5198.htm" class="author-comment" target="_blank"> "It was a pleasure tracking the article quality of the following manuscript. 1 Ethics: Not applicable given manuscript type 2 ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5198.htm" target="_blank" class="author-comment"> "It was a pleasure tracking the article quality of the following manuscript. 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: Not applicable - none included 5 Biostatistics: Not applicable given manuscript type 6 References: References are recent/appropriate 7 Language: This is a concise/well written manuscript 8 Caveats or drawbacks: None" </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Moyana TN. Small cell lung carcinoma metastatic to the stomach: Commonly overlooked, limited treatment options. <em>World J Gastroenterol</em> 2024; 30(48): 5198-5204 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 4 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/100160.htm" class="author-comment" target="_blank"> "Both Safiullah Sarker's letter to the editor and the publication by Murt A, Altiparmak MR. et al. Acute kidney injury related to ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/100160.htm" target="_blank" class="author-comment"> "Both Safiullah Sarker's letter to the editor and the publication by Murt A, Altiparmak MR. et al. Acute kidney injury related to rhabdomyolysis in patients with COVID-19. Mundo J Virol. 2024;13(3):91107. doi: 10.5501/wjv.v13.i3.91107. provide very valuable information. For example, the conclusions of Murt A should be made known in other editorials. Rhabdomyolysis is an important cause of AKI and may complicate the clinical course of COVID-19. In addition to rhabdomyolysis, it should be suspected if elevated markers of inflammation, D-dimer, pro-BNP and hyperkalemia are observed. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Sarker MS. Rhabdomyolysis-related acute kidney injury in COVID-19: A critical concern. <em>World J Virol</em> 2025; 14(1): 100160 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 5 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/100338.htm" class="author-comment" target="_blank"> "The manuscript by Pinheiro MG et al has information in the introduction (e.g. obesity) that may be irrelevant for the purpose of ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/100338.htm" target="_blank" class="author-comment"> "The manuscript by Pinheiro MG et al has information in the introduction (e.g. obesity) that may be irrelevant for the purpose of "active surveillance of serological expression of anti-SARS-CoV-2 antibodies in individuals within a university setting during the COVID-19 pandemic", as it does not provide at least BMI data. It also does not provide study methods. The information may be valuable as long as all information is provided, as the sensitivity of laboratory tests to measure antibodies has varied considerably." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Pinheiro MG, Alves GGO, Conde MER, Costa SL, Sant’Anna RCS, Antunes IMF, Carneiro MC, Ronzei FS, Scaffo JC, Pinheiro FR, Andre LS, Povoa HC, Baltar VT, Giordani F, Hemerly ES, Alexandre GC, de Paula KC, Watanabe M, Nóbrega ACLD, Lobato JCP, Aguiar-Alves F. Serological surveillance for SARS-CoV-2 antibodies among students, faculty and staff within a large university system during the pandemic. <em>World J Virol</em> 2025; 14(1): 100338 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 6 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3192/full/v13/i2/97723.htm" class="author-comment" target="_blank"> "Thank you for giving me this opportunity for selection of paper for award. however, I find following comments for and found that it ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3192/full/v13/i2/97723.htm" target="_blank" class="author-comment"> "Thank you for giving me this opportunity for selection of paper for award. however, I find following comments for and found that it is not suitable for award “Walsh HA. Preterminal protein, the achilles heel of adenoviridae: Implications for adenoviral infections. World J Pharmacol 2024; 13(2): 97723 [DOI: 10.5497/wjp.v13.i2.97723]” 1 Ethics: Not required 2 Methods: The experimental method effective and perfect and use standard method 3 Results: The results are true and they are validated and some experiments are performed in triplicate 4. Figures and tables: The author has provided perfect figs and not confusing 5 Biostatistics Statistically not evaluated and there are no statistical bars shown 6 References: Most pf the references for cited too old. very few new /recent references are cited 7 Language: language is not clear 8 Caveats or drawbacks: Bio statistical data is not reported and References are not recent " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Walsh HA. Preterminal protein, the achilles heel of adenoviridae: Implications for adenoviral infections. <em>World J Pharmacol</em> 2024; 13(2): 97723 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 7 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/97482.htm" class="author-comment" target="_blank"> "The manuscript by Yumna Shahid, et al, among the information that is not provided and the limitations of the work are 1. It does ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/97482.htm" target="_blank" class="author-comment"> "The manuscript by Yumna Shahid, et al, among the information that is not provided and the limitations of the work are 1. It does not report the sensitivity and specificity of the methods used for diagnosis. 2. It does not indicate the presence of co-infection and superinfection. 3. It is required to discuss recent work such as DOI: 10.3390/idr16050070 DOI: 10.3390/idr16050070 3. It is suggested that the title of the paper be changed to: Increased prevalence of acute hepatitis A compared to hepatitis E among adults and clinical characteristics in a tertiary care center of Pakistan." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Shahid Y, Butt AS, Jamali I, Ismail FW. Rising incidence of acute hepatitis A among adults and clinical characteristics in a tertiary care center of Pakistan. <em>World J Virol</em> 2025; 14(1): 97482 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 8 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/96098.htm" class="author-comment" target="_blank"> "The paper by Thakur SK et al., compares the prevalence of transfusion-transmissible infections in different donor groups. In the ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/96098.htm" target="_blank" class="author-comment"> "The paper by Thakur SK et al., compares the prevalence of transfusion-transmissible infections in different donor groups. In the background, it should be noted that in other countries there are different pathogens that can be transmitted by transfusion, such as T cruzi. On the other hand, the manuscript does not mention the sensitivity and specificity for antibodies against Treponema pallidum and Plasmodium antigens. Another limitation not mentioned is the distribution of these infections by ethnic groups." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Thakur SK, Sinha AK, Sharma SK, Jahan A, Negi DK, Gupta R, Singh S. Prevalence of transfusion transmissible infections among various donor groups: A comparative analysis. <em>World J Virol</em> 2025; 14(1): 96098 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 9 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/99923.htm" class="author-comment" target="_blank"> "The author did not provide ethical approval form. This was not experimental method; this was case report and a review literature which ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/99923.htm" target="_blank" class="author-comment"> "The author did not provide ethical approval form. This was not experimental method; this was case report and a review literature which had no any hypothesis. This review aimed at providing insight into the effects of RTX on lymphocyte functions. Moreover, tables and figures are perfect since and are clearly constructed. No biostatistics was done since this was a case report. The author scientifically and reasonably cites the latest references which are important in this field and related to the scientific problems. The language in this article is correctly, clearly and concisely that expresses the information. The major drawback is the that, author did not define shock. The author could have explained the criteria used to define shock and there could have been administration of fresh frozen Platelets due to thrombocytopenia. The overall quality of the article if fair. In conclusion, in the future, the author could conduct intense review of other identified cases, which would contribute in raising the reader’s interest, and will promote discipline development. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Patel S, Jay J, Pathak P, Antony MA, Thiriveedi M. Septic shock due to cytomegalovirus colitis associated with rituximab use: A case report. <em>World J Virol</em> 2025; 14(1): 99923 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 10 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/99249.htm" class="author-comment" target="_blank"> "The author did not provide an ethical approval form. This was not experimental method; this was a review article which had no any ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3249/full/v14/i1/99249.htm" target="_blank" class="author-comment"> "The author did not provide an ethical approval form. This was not experimental method; this was a review article which had no any hypothesis. This review aimed at providing insight into the dynamic nature of HIV-related GI illnesses and the critical role that contemporary diagnostic and treatment approaches play in the management of this condition. Therefore, the author would have included HIV diagnosis, management in their search terms. The results are true and authentic according to the literatures. Moreover, the tables are perfect since are clearly constructed, although the figures are confusing and missing some diagnostic items for example figure number 2 in a HIV patient who has chronic diarrhea, author could have mentioned the stool test and add more blood tests which might identify viral diseases. This was the review article and the meta-analysis was not done which could bring the high level significance of this article. Therefore, the biostatistics was done. The author scientifically and reasonably cites the latest references which are important in this field and related to the scientific problems. The language in this article is correctly, clearly and concisely that expresses the information. Doing review alone is the major drawback of this article. The overall quality of the article if good, the author did not resolve the issue of burden of GI diseases among HIV patients. In conclusion, in the future, the author could conduct systematic review and meta-analysis research, which would contribute in raising the reader’s interest, and will promote discipline development." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Moliya P, Singh A, Singh N, Kumar V, Sohal A. Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review. <em>World J Virol</em> 2025; 14(1): 99249 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 11 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5194.htm" class="author-comment" target="_blank"> "H.pylori infection is said to be inversely related to EAC, protecting against EAC by inducing atrophic gastritis, altering serum ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5194.htm" target="_blank" class="author-comment"> "H.pylori infection is said to be inversely related to EAC, protecting against EAC by inducing atrophic gastritis, altering serum ghrelin levels, and triggering cancer cell apoptosis. Though H.pylori infection has no significant associated with ESCC, COX2-1195 polymorphisms and endogenous nitrosamine production can impact the risk of ESCC in H.pylori infected individual. Author says the prognosis of H pylori (+) after ESCC diagnosis is nine months . The author states that H. pylori positive patients have a poor prognosis for esophageal cancer. What is the reason for this?" </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Omer JI, Habtemariam AH. Revaluation of <i>Helicobacter pylori</i>'s role in esophageal carcinoma: A call for comprehensive research. <em>World J Gastroenterol</em> 2024; 30(48): 5194-5197 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 12 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5212.htm" class="author-comment" target="_blank"> "It was with pleasure that I tracked the article quality of the following manuscript: 1 Ethics: NA given manuscript type 2 Methods: ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i48/5212.htm" target="_blank" class="author-comment"> "It was with pleasure that I tracked the article quality of the following manuscript: 1 Ethics: NA given manuscript type 2 Methods: NA given manuscript type 3 Results: NA given manuscript type 4 Figures and tables: NA - none included 5 Biostatistics: NA given manuscript type 6 References: The included references are appropriate/up to date 7 Language: This is a concise/well written manuscript 8 Caveats or drawbacks: None" </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Patnaik S, Durairajan SSK, Singh AK, Krishnamoorthi S, Iyaswamy A, Mandavi SP, Jeewon R, Williams LL. Role of <i>Candida</i> species in pathogenesis, immune regulation, and prognostic tools for managing ulcerative colitis and Crohn's disease. <em>World J Gastroenterol</em> 2024; 30(48): 5212-5220 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 13 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98322.htm" class="author-comment" target="_blank"> "The manuscript titled "Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98322.htm" target="_blank" class="author-comment"> "The manuscript titled "Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes" The authors provided valuable data about the impact of glycemic history on treatment outcomes in a real-world setting. However, it has some shortcomings. - A 12-month duration may not fully capture long-term glycemic outcomes and complications. - The study cohort (132) is too small, potentially limits statistical power. - The observational nature of the study may introduce selection bias " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Erbakan AN, Arslan Bahadır M, Kaya FN, Güleç B, Vural Keskinler M, Aktemur Çelik Ü, Faydalıel Ö, Mesçi B, Oğuz A. Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes. <em>World J Diabetes</em> 2025; 16(1): 98322 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 14 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/95209.htm" class="author-comment" target="_blank"> "Authors studied the efficacy, safety, and treatment satisfaction of transitioning from an intensive insulin regimen to IDegAsp in ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/95209.htm" target="_blank" class="author-comment"> "Authors studied the efficacy, safety, and treatment satisfaction of transitioning from an intensive insulin regimen to IDegAsp in patients with T2DM in paper titled “Efficacy, safety and treatment satisfaction of transition to a regimen of insulin degludec/aspart: A pilot study”. In the clinical trial study, transitioning to a twice-daily injection regimen improved adherence and treatment satisfaction, which is crucial in managing T2DM. In addition, authors provided practical insights into transitioning patients from intensive insulin regimens to a simplified protocol in a real-world clinical setting. However, there are few issues remaining: - The non-randomized trial design may introduce bias in outcome assessment. - The 12-week study duration may not fully capture the long-term effects and safety of IDegAsp. - The study included only 21 participants, limiting the statistical power and generalizability of the findings." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Yang N, Lv L, Han SM, He LY, Li ZY, Yang YC, Ping F, Xu LL, Li W, Zhang HB, Li YX. Efficacy, safety and treatment satisfaction of transition to a regimen of insulin degludec/aspart: A pilot study. <em>World J Diabetes</em> 2025; 16(1): 95209 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 15 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/92711.htm" class="author-comment" target="_blank"> "The title "Mizagliflozin ameliorates diabetes induced kidney injury by inhibitor inhibit inflammation and oxidative stress" is ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/92711.htm" target="_blank" class="author-comment"> "The title "Mizagliflozin ameliorates diabetes induced kidney injury by inhibitor inhibit inflammation and oxidative stress" is confusing so it should be revised as "Mizagliflozin ameliorates diabetes induced kidney injury by inhibition of inflammation and oxidative stress". Authors performed a comprehensive analysis since the study’s evaluation of both animal and cell models provides valuable evidence of Mizagliflozin's therapeutic effects. Moreover the authors focused on SGLT1 inhibition which differentiates Mizagliflozin from SGLT2 inhibitors, highlighting its unique anti-inflammatory and antioxidant benefits. However few issues are detected. - The eight week study duration limits insights into long-term effects and potential chronic complications. - Authors observed weight gain in high-dose Mizagliflozin-treated mice which is concerning and this issue should be explored further. - The study could benefit from broader evaluation of inflammatory and oxidative stress markers." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Lin ZM, Gao HY, Shi SH, Li YT. Mizagliflozin ameliorates diabetes induced kidney injury by inhibitor inhibit inflammation and oxidative stress. <em>World J Diabetes</em> 2025; 16(1): 92711 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 16 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98322.htm" class="author-comment" target="_blank"> "This prospective study effectively demonstrates that glycemic background patterns significantly influence treatment outcomes in poorly ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/98322.htm" target="_blank" class="author-comment"> "This prospective study effectively demonstrates that glycemic background patterns significantly influence treatment outcomes in poorly controlled type 2 diabetes. Newly diagnosed patients show markedly better response rates than those with persistently poor control. The comprehensive analysis of multiple metabolic parameters and patient characteristics provides strong evidence for the need to personalize treatment approaches based on glycemic history. While the study establishes the importance of glycemic background in treatment success, future research should focus on longer-term outcomes, detailed mechanism studies, and the development of targeted interventions for patients with persistently poor glycemic control." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Erbakan AN, Arslan Bahadır M, Kaya FN, Güleç B, Vural Keskinler M, Aktemur Çelik Ü, Faydalıel Ö, Mesçi B, Oğuz A. Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes. <em>World J Diabetes</em> 2025; 16(1): 98322 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 17 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/99526.htm" class="author-comment" target="_blank"> "This study highlights the potential of jejunoileal side-to-side anastomosis as a promising surgical approach for managing type 2 ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v16/i1/99526.htm" target="_blank" class="author-comment"> "This study highlights the potential of jejunoileal side-to-side anastomosis as a promising surgical approach for managing type 2 diabetes mellitus, particularly in Asian populations. The findings demonstrate significant improvements across multiple metabolic parameters. This research provides a strong foundation for future investigations focused on optimizing patient selection criteria and exploring the underlying mechanisms of metabolic improvements, particularly those involving incretin hormone responses. However, limitations such as the short follow-up period and single-center design highlight the need for more extensive multicenter trials with more extended observation periods." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Wang JK, Zhang D, Wang JF, Lu WL, Wang JY, Liang SF, Liu R, Jiang JX, Li HT, Yang X. Clinical study on the effect of jejunoileal side-to-side anastomosis on metabolic parameters in patients with type 2 diabetes. <em>World J Diabetes</em> 2025; 16(1): 99526 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 18 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3870.htm" class="author-comment" target="_blank"> "1 Ethics: Informed written consent was obtained from the patient to publish this report and any accompanying images. 2 Methods: The ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3870.htm" target="_blank" class="author-comment"> "1 Ethics: Informed written consent was obtained from the patient to publish this report and any accompanying images. 2 Methods: The description is exact and can be repeated according to adequate textual/citation content presented. 3 Results: The results look true and authentic. This is an extremely rare condition, and it is difficult to discuss its universal significance and whether it is validated or partially validated. 4 Figures and tables: The authors provide perfect tables, line charts and/or graphs. 5 Biostatistics: This is a case report without the possibility of statistics. 6 References: The authors scientifically and reasonably cite the latest references, which are important in this field and related to the scientific problems and research hypotheses addressed in the study. 7 Language: The language in the article looks correct, clear, and concisely expresses the information. Unfortunately, I am not a native English speaker. 8 Caveats or drawbacks: No any special. This is good educational video. Nothing new or novel but good educational video." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Zhao PJ, Ma Y, Yang JW. Laparoscopic cholecystectomy with communicating accessory hepatic duct injury and management: A case report. <em>World J Gastrointest Surg</em> 2024; 16(12): 3870-3874 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 19 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3862.htm" class="author-comment" target="_blank"> "1 Ethics: Informed written consent was obtained from the patient to publish this report and any accompanying images. 2 Methods: The ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9366/full/v16/i12/3862.htm" target="_blank" class="author-comment"> "1 Ethics: Informed written consent was obtained from the patient to publish this report and any accompanying images. 2 Methods: The description is exact and can be repeated according to adequate textual/citation content presented. 3 Results: The results look true and authentic. This is an extremely rare condition, and it is difficult to discuss its universal significance and whether it is validated or partially validated. 4 Figures and tables: The authors provide perfect tables, line charts and/or graphs. 5 Biostatistics: This is a case report without the possibility of statistics. 6 References: The authors scientifically and reasonably cite the latest references, which are important in this field and related to the scientific problems and research hypotheses addressed in the study. 7 Language: The language in the article looks correct, clear, and concisely expresses the information. Unfortunately, I am not a native English speaker. 8 Caveats or drawbacks: Different terms for the pathology are used - mucous adenocarcinoma, Mucosal adenocarcinoma, mucosa adenocarcinoma. Adenocarcinomas start in the mucosa and then these are carcinomas in situ. How can it be mucosal carcinoma. And if mucosal, how had spead to other layers of duodenal wall. Also, although not a native English spearker, I have never heard of medical term ''circumintestinal cavity''" </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Zhang JY, Wu LS, Yan J, Jiang Q, Li XQ. Pathological diagnosis and clinical feature analysis of descending duodenal mucosal adenocarcinoma: A case report. <em>World J Gastrointest Surg</em> 2024; 16(12): 3862-3869 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 20 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i12/2338.htm" class="author-comment" target="_blank"> "This is a study that validates the effect of plant-based medicine in promoting the healing of diabetic wounds through basic research. ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i12/2338.htm" target="_blank" class="author-comment"> "This is a study that validates the effect of plant-based medicine in promoting the healing of diabetic wounds through basic research. The study has significant clinical implications. In traditional Chinese medicine, Zi Cao is used to treat burns and scalds. The abstract of this study suggests that Shikonin is a natural remedy effective in treating diabetic wounds. However, this lacks support from clinical literature. I recommend further exploration of its clinical effects and reporting in future clinical practice. Additionally, it is worth researching the additional benefits of plant-based antidiabetic medications in treating difficult-to-heal wounds (Phytomedicine. 2024 Nov;134:155990)." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Cen LS, Cao Y, Zhou YM, Guo J, Xue JW. Shikonin protects mitochondria through the NFAT5/AMPK pathway for the treatment of diabetic wounds. <em>World J Diabetes</em> 2024; 15(12): 2338-2352 </div> </div> </div> <div class="more"> <span>15014 items</span>  <a href="https://www.f6publishing.com/ArticleQualityTrackings" target="_blank">Read more >></a> </div> </div> </div> <div class="mnavbar"> <div> Peer-Reviewers and Manuscript Statistics </div> </div> <div class="mnavbox"> <div class="reviewstat cl"> <dl> <dt>Editorial board members</dt> <dd><a 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Advances in minimally invasive treatment of malignant obstructive jaundice. <i><i>World J Gastrointest Surg</i></i> 2024; 16(12): 3650-3654</p> </a> </div> <div class="count"> 2024-11-28 | Browse: 23 | Download: 27 </div> </div> </div> <div class="more"> <span>8985 items</span>  <a href="https://www.f6publishing.com/FeaturedArticles" target="_blank">Read more >></a> </div> </div> </div> <div class="mnavbar"> <div> <a href="https://www.f6publishing.com/ArticleKeywords?Type=2" target="_blank">Keyword Search Published Articles Processes</a> </div> </div> <div class="mnavbox"> <div class="articlelist cl"> <div class="keyworditem cl"> <div class="num fl"> 1 </div> <div class="title fl"> <a href="https://www.f6publishing.com/ArticlesByKeywords?type=2&pageNumber=1&keyword=Case+report" target="_blank"> Case report </a> </div> <div class="count fr"> 2852 </div> </div> <div class="keyworditem cl"> <div class="num fl"> 2 </div> <div class="title fl"> <a 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onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i47/5081.htm" class="author-comment" target="_blank"> "he significant impact of surgical approaches on male sexual dysfunction after rectal cancer surgery is highlighted by both this letter to the editor and the latest study by Numata et al. published in Annals of Surgery1). Damage to the autonomic nervous system during rectal cancer surgery is a major cause of sexual dysfunction, with problems such as ejaculatory dysfunction, erectile dysfunction, and sexual dysfunction commonly reported. These complications are particularly common with open surgery, and previous research has also shown that the incidence of sexual dysfunction following surgery is high. However, advances in surgical techniques such as robotic surgery are expected to reduce these complications. The LANDMARC Study provided convincing evidence that robotic surgery significantly reduces the incidence of postoperative sexual dysfunction compared to laparoscopic surgery. The incidence of ejaculatory dysfunction at 12 months postoperatively was 25% in robotic surgery patients compared to 40.9% in laparoscopic surgery patients. The incidence of sexual dysfunction was 17.8% and 29%, respectively. This letter to editor alos emphasized the importance of accurate surgical technique and knowledge of pelvic nerve anatomy. It also discussed the benefits of new techniques such as robotic surgery and transanal total mesorectal excision (Ta-TME), as well as the use of intraoperative pelvic nerve monitoring. These advances enhance nerve preservation, reduce complications, and improve patients' postoperative quality of life. These findings highlight the need to adapt innovative surgical techniques in rectal cancer treatment to minimize adverse effects on sexual health while maintaining oncologic effectiveness. 1) Numata, Masakatsu, et al. "Prospective Multicenter Comprehensive Survey on Male Sexual Dysfunction following Laparoscopic, Robotic, and Transanal Approaches for Rectal Cancer (the LANDMARC Study)." Annals of Surgery: 10-1097 " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Kolokotronis T, Pantelis D. Urinary and sexual dysfunction after rectal cancer surgery: A surgical challenge. <em>World J Gastroenterol</em> 2024; 30(47): 5081-5085 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 2 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2307-8960/full/v13/i6/100673.htm" class="author-comment" target="_blank"> "since the patient also had general anesthesia, it should be clairifed to whihc degree analgesics given for the procedure prevented ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2307-8960/full/v13/i6/100673.htm" class="author-comment" target="_blank"> "since the patient also had general anesthesia, it should be clairifed to whihc degree analgesics given for the procedure prevented the patient from experienceing severe pain xxxx xx x x x x x x x x x x x x x x x x x x x x x x xx x x x x x xx " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Chen KH, Kang MY, Chang YT, Huang SY, Wu YS. Enhancing postoperative pain control by surgically-initiated rectus sheath block in abdominal aortic aneurysm open repair: A case report. <em>World J Clin Cases</em> 2025; 13(6): 100673 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 3 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i12/2285.htm" class="author-comment" target="_blank"> "The novelty of the topic is very important, suitable for fine rather than too broad content. The interpretation of statistical results ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i12/2285.htm" class="author-comment" target="_blank"> "The novelty of the topic is very important, suitable for fine rather than too broad content. The interpretation of statistical results needs to be rigorous, correlation does not mean causation, and the HR presented may be inaccurate. The discussion needs to be tightly focused on the results and not extend to other unwarranted conclusions. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Chen DQ, Wu YX, Zhang YX, Yang HL, Huang HH, Lv JY, Xiao Q. Sarcopenia-associated factors and their bone mineral density levels in middle-aged and elderly male type 2 diabetes patients. <em>World J Diabetes</em> 2024; 15(12): 2285-2292 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 4 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i46/4969.htm" class="author-comment" target="_blank"> "I would like to commend the authors for their comprehensive analysis of the complex interplay between gut microbiota, mesenteric ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i46/4969.htm" class="author-comment" target="_blank"> "I would like to commend the authors for their comprehensive analysis of the complex interplay between gut microbiota, mesenteric adipose tissue (MAT), and creeping fat (CF) in the context of Crohn’s disease (CD). The manuscript provides a valuable contribution to the field. The article meticulously elucidates the profound clinical significance of the interplay between the gut microbiota and MAT/CF. The authors have not only reviewed the current body of knowledge but have also contributed novel insights into the role of MAT and CF in shaping CD phenotypes and treatment strategies.The structure of the letter is well-organized, making it easy to follow the authors' line of reasoning. The abstract succinctly captures the essence of the study, and the core tip effectively highlights the main takeaways for the reader.The exploration of fecal microbiota transplantation (FMT) as a therapeutic strategy is both timely and relevant. The authors have successfully linked the current understanding of microbial imbalances to potential clinical applications, which could influence future treatment protocols for CD. In conclusion, Hasnaoui et al. have provided a thought-provoking analysis of the role of gut microbiota and MAT/CF in CD. Their work not only advances our understanding of the disease but also offers promising avenues for therapeutic intervention. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Hasnaoui A, Trigui R, Giuffrida M. Gut microbiota and mesenteric adipose tissue interactions in shaping phenotypes and treatment strategies for Crohn’s disease. <em>World J Gastroenterol</em> 2024; 30(46): 4969-4976 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 5 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i45/4836.htm" class="author-comment" target="_blank"> "The author suggests to use in all diabetic patients an interesting technique, the” body surface gastric mapping” (BSGM), to detect ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i45/4836.htm" class="author-comment" target="_blank"> "The author suggests to use in all diabetic patients an interesting technique, the” body surface gastric mapping” (BSGM), to detect the onset of gastric dysmotility precursor of gastroparesis, instead of invasive procedures, as gastroscopy, manometry, emptying of radiopaque markers or radioactive bolus and breath tests . The idea is interesting , but there are some observations to make. First of all the author forgot a simple, not invasive, physiologic and reliable method to measure gastric emptying, that is real-time ultrasonography, which allows the use of a normal solid–liquid meal and gives an immediate result (1). Furthermore the author did not take into account the fact that, as indicated in figure 1 of ref. 4, the cause of delayed gastric emptying in gastroparesis may be also due, not only to antral dysmotility detectable with BSGM, but also to impaired pyloric relaxation upon arrival of antral peristalsis (pylorospasm) and, sometimes, to dysmotility of duodenum, which does not accept the bolus coming from the stomach. The pylorospasm, which was observed in 14 of 24 diabetics, by Mearin et al (2) forms part of the widespread disruption of gut motility that affects some patients with diabetes. Unfortunately these pyloric and duodenal motor abnormalities are not detected by the technique of BSGM, which could find a normal antral motility, giving the impression that everything is OK, while the gastric emptying is already delayed. Therefore I would suggest to monitor the diabetic patients with the real-time ultrasonography, which is able to detect also a minimal delay in gastric emptying harbinger of gastroparesis, and, if the gastric emptying is delayed, then perform the BSGM, to see if the cause of the slowing is due to antral dysmotility. If the latter examination is negative, then the cause of delayed gastric emptying shoul be pylorospasm or duodenal dysmotility. REFERENCES 1) Bolondi L, Bortolotti M, Santi V, Calletti T, Gaiani S, Labò G. Measurement of gastric emptying time by real-time ultrasonography. Gastroenterology. 1985 Oct; 89(4):752-9.PMID:3896910. 2) Mearin F, Camilleri M, Malagelada JR. Pyloric dysfunction in diabetics with recurrent nausea and vomiting. Gastroenterology. 1986 Jun;90(6):1919-25. doi: 10.1016/0016-5085(86)90262-3. PMID: 3699409 " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Mori H. Early detection and intervention in diabetic gastroparesis: Role of body surface gastric mapping. <em>World J Gastroenterol</em> 2024; 30(45): 4836-4838 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 6 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5190/full/v16/i11/617.htm" class="author-comment" target="_blank"> "This article presents a case report of air embolism occurring during endoscopic retrograde cholangiopancreatography (ERCP), ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5190/full/v16/i11/617.htm" class="author-comment" target="_blank"> "This article presents a case report of air embolism occurring during endoscopic retrograde cholangiopancreatography (ERCP), emphasizing the necessity for gastroenterologists to maintain a high level of vigilance regarding this potential complication during such procedures. While ERCP is a widely used and effective diagnostic and therapeutic technique, air embolism represents a serious complication that can significantly jeopardize patient health. Consequently, this article not only reviews pertinent cases and analyzes the mechanisms, clinical manifestations, and countermeasures associated with air embolism but also underscores the importance of preventive measures that medical staff should implement to minimize the incidence of such complications during ERCP. The aim of this article is to provide a comprehensive overview of relevant knowledge, thereby enabling medical professionals to better understand and address this issue, ultimately enhancing the safety and effectiveness of clinical operations. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Li JH, Luo ZK, Zhang Y, Lu TT, Deng Y, Shu RT, Yu H. Systemic air embolism associated with endoscopic retrograde cholangiopancreatography: A case report. <em>World J Gastrointest Endosc</em> 2024; 16(11): 617-622 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 7 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i11/2203.htm" class="author-comment" target="_blank"> "Exercise during pregnancy improve organ development in offspring with gestational diabetes mellitus Shengju Chen, Hangming Fan, Yu ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i11/2203.htm" class="author-comment" target="_blank"> "Exercise during pregnancy improve organ development in offspring with gestational diabetes mellitus Shengju Chen, Hangming Fan, Yu Chen Abstract In this commentary, we discuss the study by Tang et al., “Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus”. Gestational diabetes mellitus (GDM), defined as ‘glucose intolerance with onset or first recognition during pregnancy’, impacts millions of women worldwide and poses significant health risks. Exercise during pregnancy has been shown to improve offspring health outcomes in obese mothers, potentially reducing epigenetic changes associated with maternal high-fat diets and minimizing abnormalities in lipid and glucose metabolism. However, while prenatal exercise’s impact on metabolic disorders in GDM offspring has been explored, its effects on organ growth remain insufficiently understood. Tang et al. identified GLUT1 and HIF1 as key regulators influencing the development of the heart, liver, and kidney in GDM offspring. Their study demonstrates that exercise during pregnancy supports organ development by inhibiting placental GLUT1 and HIF1 expression in GDM. This work contributes to understanding the role of GLUT1 and HIF1 in moderating the effects of prenatal exercise on organ development in GDM-affected offspring, supporting the idea that maternal exercise is an important intervention for improving offspring outcomes in GDM pregnancies and warrants further investigation in future epigenetic research. Introduction Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications, affecting approximately 20.9 million pregnant women and their newborns worldwide as of 2020. GDM is associated with a range of adverse pregnancy outcomes, including preeclampsia, polyhydramnios, and fetal organomegaly (Pettitt et al., 1980). Additionally, GDM poses several short-term risks to offspring, such as neonatal respiratory distress, metabolic complications (Ferrara et al., 2007), and increased perinatal mortality rates. The GDM quintet management model recommends five core interventions to mitigate these risks, exercise, dietary regulation, maternal education, pharmacological treatment, and fetal health evaluation (Association, 2003). Pathophysiologically, GDM is characterized by hyperglycemia, glucose intolerance, and insulin resistance, typically manifesting in the late second to early third trimester of pregnancy (Buchanan et al., 2012, Jovanovic and Pettitt, 2001, Pereira et al., 2015). Several mechanisms have been proposed to explain these outcomes, including chronic fetal hyperinsulinemia, impaired oxygenation due to elevated metabolic rates, and metabolic acidosis (Freinkel, 1980). In this commentary, we discuss the article by Tang et al., recently published in the recent issue of the World Journal of Diabetes, which explores the impact of maternal exercise during pregnancy on organ development in offspring of mothers with GDM. Risks and complications associated with GDM In a healthy pregnancy, insulin sensitivity decreases to allow more glucose availability for the fetus; however, normoglycemia is typically maintained through increased insulin production by pancreatic β-cells. In cases of GDM, the pancreas may fail to produce sufficient insulin, resulting in elevated blood glucose levels and the onset of GDM (Freinkel, 1980). GDM pregnancies can lead to additional complications that negatively impact maternal and fetal health (Poston et al., 2011). Immediate complications in offspring of overweight women with GDM include macrosomia, the most severe of which is shoulder dystocia; other neonatal complications such as hypoglycemia and hyperbilirubinemia have also been reported (Kaaja and Rönnemaa, 2008, Lecomte et al., 2017). Long-term exposure to GDM increases the risk of obesity, type 2 diabetes, and cardiovascular diseases (CVD) as offspring age (Capobianco et al., 2016). Epigenetic studies indicate that the intrauterine environment significantly influences offspring organ development, and exposure to elevated maternal blood levels can impair fetal health. Maintaining a healthy uterine environment is thus essential to promoting favorable health outcomes in offspring. Exercise, as a non-pharmacological intervention without side effects, is widely used in diabetes prevention and management. Given that pregnancy is a period when non-pharmacological interventions are especially favored by medical staff and patients, exercise is particularly promising for managing GDM. Benefits of exercise during pregnancy Eight national guidelines on exercise during pregnancy recommend 60-150 minutes of aerobic exercise per week for healthy pregnant women (Savvaki et al., 2018). The benefits of exercise for pregnant women include improved overall health, better weight management, reduced risk of GDM and gestational hypertension (Davenport et al., 2018, Yu et al., 2018). For women with GDM, moderate aerobic or combined exercise has been shown to enhance postprandial blood glucose control (Walter and Klaus, 2014), although the optimal duration and intensity remain unclear. Moderate exercise during pregnancy can improve maternal insulin sensitivity, reduce placental lipid accumulation in both male and female fetuses, and alleviate hypoxia, positively influencing the intrauterine environment and fetal growth (Laker et al., 2014). Exercise during pregnancy also promotes healthier liver glucose production, helps maintain liver triglycerides levels, and prevents the expression of liver enzymes and genes in offspring caused by maternal high-fat diet, thereby improving the offspring’s metabolic profile. These findings suggest that maternal exercise can mitigate modifications linked to a high-fat diet, protecting offspring from future metabolic diseases. Regulation of GLUT1 by maternal exercise and offspring health outcomes in GDM The placenta is responsible for transporting essential nutrients and oxygen from maternal to fetal circulation, as fetal gluconeogenesis is minimal (Kalhan and Parimi, 2000). GDM disrupts placental function, leading to various morphological (Treesh and Khair, 2015) and vascular changes (Aldahmash et al., 2022, El Sawy et al., 2018) and including fetal vascular changes and DNA methylation (Song et al., 2022). Placental transport proteins, such as glucose transporters, facilitate nutrient transfer from the mother to the fetus. Glucose is the primary energy source for both placental and fetal growth (Stanirowski et al., 2017), with GLUT1 and GLUT3 serving as the main placental glucose transport proteins in humans. GLUT1 is expressed in syncytiotrophoblast microvilli and the basal membrane, as well as in vascular endothelium and cell layers (Brown et al., 2011, Jansson et al., 1993). Research on GDM in humans and mice shows increased placental GLUT1 expression, likely due to increased glucose availability in maternal circulation, which enhances placental glucose consumption (Muralimanoharan et al., 2016). This increase in GLUT1 may contribute to the higher rates of macrosomia observed in GDM pregnancies (Stanirowski et al., 2022). Moreover, GDM leads to placental hypoxia, elevated hypoxia-inducible (HIF) levels, and glial cell missing 1 degradation, inhibiting trophoblast migration and invasion. Exercise during pregnancy can significantly reduce placental GLUT1 expression and alleviate hypoxia. Silencing GLUT1 can partially counteract the reduced trophoblast migration caused by hyperglycemia and hypoxia. Beyond energy metabolism, GLUT1 is also related to the development of the heart, liver, and kidneys. Zhang et al. investigated the relationship between GLUT1 expression in these organs and their structural and pathological changes, examining how exercise influences growth and development in offspring with GDM. In a neonatal GLUT1 transgenic heart model, increased glucose metabolism can stimulate hyperplastic growth after cardiac injury (Fajardo et al., 2021). Maternal exercise during pregnancy has been shown to lower hepatic GLUT1 expression, reduce inflammatory infiltration, and decrease the risk of liver disease in adult offspring (Baker and Friedman, 2018). In the kidney, GLUT1 functions vary by cell type; elevated GLUT1 in mesangial cells can impair kidney structure, while in podocytes, it may reduce mesangial expansion and fibronectin accumulation (Chen et al., 2024). Future research is recommended to clarify the specific mechanisms by which exercise benefits renal structure and function in GDM offspring. Directions for future studies The specific mechanisms by which maternal exercise during pregnancy improves health outcomes in diabetic offspring remain under investigation, with multiple synergistic pathways likely involved. Given its role in glucose metabolism, GLUT1 is of particular interest as a regulatory factor in mitigating adverse outcomes in offspring of mothers with GDM through exercise. This underscores the significant influence of exercise on glucose metabolism, which enhances the intrauterine environment and supports offspring health. Improved placental GLUT1 expression appears to regulate the GLUT1 levels in offspring organs, positively impacting organ development. These findings extend our understanding of exercise-related epigenetics modifications, yet further research is essential to clarify the pathways through which maternal exercise regulates placental GLUT1, thereby promoting healthy organ development in offspring and underscoring the benefits of prenatal exercise. Conclusion GDM can lead to adverse outcomes for both the mother and their offspring. Maternal exercise during pregnancy improves the intrauterine environment and enhances offspring health. Elevated maternal blood glucose can cause fetal hyperinsulinemia, hypoxia, and metabolic acidosis. Exercise enhances glucose metabolism, reduces high blood sugar levels, and supports a healthier intrauterine environment, thereby decreasing the risk of metabolic diseases in offspring. The study by Tang et al. confirms the association between elevated placental GLUT1 expression in GDM and abnormal offspring organ development related to hypoxia. Their research demonstrates that exercise during pregnancy can improve placental glucose transport and reduce hypoxia, mitigating adverse developmental outcomes in offspring organs at various stages. These findings validate, across human, animal, and cellular models, the molecular mechanisms through which maternal exercise enhances organ development in offspring affected by GDM. This contributes to clinical application and emphasizes the role of epigenetics in promoting offspring health. As research in epigenetic progresses, the pathways through exercise benefits GDM-affected offspring will become clearer, with GLUT1 as a central regulator of glucose metabolism. Further investigation into these mechanisms will advance our understanding of how maternal exercise supports healthier outcomes for GDM offspring. Aldahmash, W.M., Alwasel, S.H., Aljerian, K., 2022. Gestational diabetes mellitus induces placental vasculopathies. Environ Sci Pollut Res Int 29 (13), 19860-19868. Association, A.D., 2003. Gestational diabetes mellitus. Diabetes Care 26 Suppl 1, S103-105. Baker, P.R., 2nd, Friedman, J.E., 2018. Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease. J Clin Invest 128 (9), 3692-3703. Brown, K., Heller, D.S., Zamudio, S., Illsley, N.P., 2011. Glucose transporter 3 (GLUT3) protein expression in human placenta across gestation. Placenta 32 (12), 1041-1049. Buchanan, T.A., Xiang, A.H., Page, K.A., 2012. Gestational diabetes mellitus: risks and management during and after pregnancy. Nat Rev Endocrinol 8 (11), 639-649. Capobianco, E., Fornes, D., Linenberg, I., Powell, T.L., Jansson, T., Jawerbaum, A., 2016. A novel rat model of gestational diabetes induced by intrauterine programming is associated with alterations in placental signaling and fetal overgrowth. Mol Cell Endocrinol 422, 221-232. Chen, Y., Bai, X., Chen, J., Huang, M., Hong, Q., Ouyang, Q., Sun, X., Zhang, Y., Liu, J., Wang, X., Wu, L., Chen, X., 2024. Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease. Cell Prolif 57 (2), e13548. Davenport, M.H., Ruchat, S.M., Poitras, V.J., Jaramillo Garcia, A., Gray, C.E., Barrowman, N., Skow, R.J., Meah, V.L., Riske, L., Sobierajski, F., James, M., Kathol, A.J., Nuspl, M., Marchand, A.A., Nagpal, T.S., Slater, L.G., Weeks, A., Adamo, K.B., Davies, G.A., Barakat, R., Mottola, M.F., 2018. Prenatal exercise for the prevention of gestational diabetes mellitus and hypertensive disorders of pregnancy: a systematic review and meta-analysis. Br J Sports Med 52 (21), 1367-1375. El Sawy, N.A., Iqbal, M.S., Alkushi, A.G., EL Sawy, N., Iqbal, M., Alkushi, A., 2018. Histomorphological study of placenta in gestational diabetes mellitus. Int. J. Morphol 36 (2), 687-692. Fajardo, V.M., Feng, I., Chen, B.Y., Perez-Ramirez, C.A., Shi, B., Clark, P., Tian, R., Lien, C.L., Pellegrini, M., Christofk, H., Nakano, H., Nakano, A., 2021. GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration. Sci Rep 11 (1), 8669. Ferrara, A., Weiss, N.S., Hedderson, M.M., Quesenberry, C.P., Jr., Selby, J.V., Ergas, I.J., Peng, T., Escobar, G.J., Pettitt, D.J., Sacks, D.A., 2007. Pregnancy plasma glucose levels exceeding the American Diabetes Association thresholds, but below the National Diabetes Data Group thresholds for gestational diabetes mellitus, are related to the risk of neonatal macrosomia, hypoglycaemia and hyperbilirubinaemia. Diabetologia 50 (2), 298-306. Freinkel, N., 1980. Banting Lecture 1980. Of pregnancy and progeny. Diabetes 29 (12), 1023-1035. Jansson, T., Wennergren, M., Illsley, N.P., 1993. Glucose transporter protein expression in human placenta throughout gestation and in intrauterine growth retardation. J Clin Endocrinol Metab 77 (6), 1554-1562. Jovanovic, L., Pettitt, D.J., 2001. Gestational diabetes mellitus. Jama 286 (20), 2516-2518. Kaaja, R., Rönnemaa, T., 2008. Gestational diabetes: pathogenesis and consequences to mother and offspring. Rev Diabet Stud 5 (4), 194-202. Kalhan, S., Parimi, P., 2000. Gluconeogenesis in the fetus and neonate. Semin Perinatol 24 (2), 94-106. Laker, R.C., Lillard, T.S., Okutsu, M., Zhang, M., Hoehn, K.L., Connelly, J.J., Yan, Z., 2014. Exercise prevents maternal high-fat diet-induced hypermethylation of the Pgc-1α gene and age-dependent metabolic dysfunction in the offspring. Diabetes 63 (5), 1605-1611. Lecomte, V., Maloney, C.A., Wang, K.W., Morris, M.J., 2017. Effects of paternal obesity on growth and adiposity of male rat offspring. Am J Physiol Endocrinol Metab 312 (2), E117-e125. Muralimanoharan, S., Maloyan, A., Myatt, L., 2016. Mitochondrial function and glucose metabolism in the placenta with gestational diabetes mellitus: role of miR-143. Clin Sci (Lond) 130 (11), 931-941. Pereira, T.J., Moyce, B.L., Kereliuk, S.M., Dolinsky, V.W., 2015. Influence of maternal overnutrition and gestational diabetes on the programming of metabolic health outcomes in the offspring: experimental evidence. Biochem Cell Biol 93 (5), 438-451. Pettitt, D.J., Knowler, W.C., Baird, H.R., Bennett, P.H., 1980. Gestational diabetes: infant and maternal complications of pregnancy in relation to third-trimester glucose tolerance in the Pima Indians. Diabetes Care 3 (3), 458-464. Poston, L., Harthoorn, L.F., Van Der Beek, E.M., 2011. Obesity in pregnancy: implications for the mother and lifelong health of the child. A consensus statement. Pediatr Res 69 (2), 175-180. Savvaki, D., Taousani, E., Goulis, D.G., Tsirou, E., Voziki, E., Douda, H., Nikolettos, N., Tokmakidis, S.P., 2018. Guidelines for exercise during normal pregnancy and gestational diabetes: a review of international recommendations. Hormones (Athens) 17 (4), 521-529. Song, J.Y., Lee, K.E., Byeon, E.J., Choi, J., Kim, S.J., Shin, J.E., 2022. Maternal Gestational Diabetes Influences DNA Methylation in the Serotonin System in the Human Placenta. Life (Basel) 12 (11). Stanirowski, P.J., Szukiewicz, D., Majewska, A., Wątroba, M., Pyzlak, M., Bomba-Opoń, D., Wielgoś, M., 2022. Placental expression of glucose transporters GLUT-1, GLUT-3, GLUT-8 and GLUT-12 in pregnancies complicated by gestational and type 1 diabetes mellitus. J Diabetes Investig 13 (3), 560-570. Stanirowski, P.J., Szukiewicz, D., Pyzlak, M., Abdalla, N., Sawicki, W., Cendrowski, K., 2017. Impact of pre-gestational and gestational diabetes mellitus on the expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 in human term placenta. Endocrine 55 (3), 799-808. Treesh, S.A., Khair, N.S.B., 2015. Histological Changes of the Human Placenta in Pregnancies Complicated with Diabetes. Journal of Cytology and Histology 6, 1-7. Walter, I., Klaus, S., 2014. Maternal high-fat diet consumption impairs exercise performance in offspring. J Nutr Sci 3, e61. Yu, Y., Xie, R., Shen, C., Shu, L., 2018. Effect of exercise during pregnancy to prevent gestational diabetes mellitus: a systematic review and meta-analysis. J Matern Fetal Neonatal Med 31 (12), 1632-1637. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Tang YB, Wang LS, Wu YH, Zhang LX, Hu LY, Wu Q, Zhou ML, Liang ZX. Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus. <em>World J Diabetes</em> 2024; 15(11): 2203-2219 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 8 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5190/full/v16/i11/587.htm" class="author-comment" target="_blank"> "I would love to congratulate the authors for writing this excellent editorial about malignant gastric outlet obstruction. The authors ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5190/full/v16/i11/587.htm" class="author-comment" target="_blank"> "I would love to congratulate the authors for writing this excellent editorial about malignant gastric outlet obstruction. The authors have given an overview of the changing spectrum of therapeutic modalities from surgery to endoscopic stenting to the latest EUS-guided interventions. There was an enlightening discussion about the potential benefit of stomach-partitioning gastrojejunostomy to reduce the rate of delayed gastric emptying. The authors have rightly advocated the need for a holistic approach to treat patients with malignant gastric outlet obstructions, keeping in mind their nutritional and clinical status. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Jiang L, Chen XP. Treatment of choice for malignant gastric outlet obstruction: More than clearing the road. <em>World J Gastrointest Endosc</em> 2024; 16(11): 587-594 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 9 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5190/full/v16/i11/617.htm" class="author-comment" target="_blank"> "I would like to congratulate the authors for reporting a rare but potentially treatable complication of ERCP. The authors have clearly ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5190/full/v16/i11/617.htm" class="author-comment" target="_blank"> "I would like to congratulate the authors for reporting a rare but potentially treatable complication of ERCP. The authors have clearly stated the scenarios when air embolism should be suspected in a patient undergoing ERCP. The authors have beautifully shown the relevant images showing air embolism. They have also discussed in detail about the timing and efficacy of hyperbaric oxygen therapy for such patients. As GI endoscopists doing regular ERCP, we should be aware of all the potential complications of ERCP, their manifestations, how to diagnose them early and the readily available treatment modalities and availability. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Li JH, Luo ZK, Zhang Y, Lu TT, Deng Y, Shu RT, Yu H. Systemic air embolism associated with endoscopic retrograde cholangiopancreatography: A case report. <em>World J Gastrointest Endosc</em> 2024; 16(11): 617-622 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 10 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2220-3206/full/v14/i10/1573.htm" class="author-comment" target="_blank"> "Re-evaluating the clinical impact of functional regulatory variants Ying Ming, Yun-Ling Du, Meng-Na Zhang Ying Ming, Molecular ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2220-3206/full/v14/i10/1573.htm" class="author-comment" target="_blank"> "Re-evaluating the clinical impact of functional regulatory variants Ying Ming, Yun-Ling Du, Meng-Na Zhang Ying Ming, Molecular Diagnosis Center,The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China Yun-Ling Du, Molecular Diagnosis Center,The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China Meng-Na Zhang, Molecular Diagnosis Center,The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China Meng-Na Zhang, Hebei Key Laboratory of Panvascular Diseases, Chengde, 067000, China ORCID number: Ying Ming (0009-0006-2161-8207) , Yun-Ling Du (0000-0001-7624-3226) , Meng-Na Zhang (0000-0001-7624-3226) Author contributions: Ying Ming contributed to the initial drafting of the work; Yun-Ling Du contributed to the drafting process; Meng-Na Zhang contributed to the initial drafting and provided overall supervision to the drafting process; All authors have read and approved the final version of the manuscript. Conflict-of-interest statement: The authors declare that they have no conflict of interest. Corresponding author: Meng-Na Zhang, Molecular Diagnosis Center,The Affiliated Hospital of Chengde Medical University, Chengde, China zhangmengna2014@sina.com Abstract Serotonin 1A receptor polymorphism (5-HTR1A) C-1019G polymorphism (rs6295) is a functional regulatory variants reported to be related with multiple phenotypes including major depression, suicidal behavior and antidepressant response. However, clinical studies investigating this variant and its potential phenotypes had incongruous findings. Molecular studies on this variant showed it does regulate HTR1A expression but meta-analysis showed it had negative relationship with antidepressant drug response in major depressive disorder (MDD), as reported by Wu et al. in the lasted issue of the World Journal of Psychiatry. This suggested the importance of re-evaluating the clinical impact of functional regulatory variants. Key words: regulatory variants, snp-meta, snp-phenotype association Core Tip: Functional regulatory variants might have negative relationship with putative phenotypes even it do regulate gene expression. Single nucleotide polymorphism (SNP) meta analysis helps to identify a more robust SNP-phenotype relationship. We carefully read the article titled “Association between 5-HTR1A gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis” published in the World Journal of Psychiatry by Wu et al.[1]. In this study the authors reviewed 11 clinical studies about serotonin 1A receptor polymorphism (5-HTR1A) C-1019G polymorphism (rs6295) and antidepressant response. Though reported to be related with major depression[2], suicidal behavior[3] and antidepressant response[4], rs6295 did not show significant association with antidepressant drug response in major depressive disorder (MDD) in this meta-analysis. Genome-wide association studies (GWAS) show to be a useful tool to investigate the effect of polymorphism on clinical phenotypes. Most disease-associated variants are non-coding variants. Researchers have developed multiple methods to identify functional regulatory variants from putative regulatory regions and their cis-regulated genes, like massively parallel reporter assays (MPRAs) and expression quantitative trait loci (eQTL)[5,6]. The 5-HTR1A C-1019G polymorphism (rs6295) reviewed by Wu et al. [1] is a functional upstream variant that affects HTR1A expression but not associates with antidepressant response in patients with MDD, though the 5-HT1A receptor is a primary target for most antidepressant drugs. This variant has been reported to influence HTR1A expression in numerous molecular studies. The C-allele of this variant is capable of interacting with transcription factors (TFs) such as Hes1, Hes5, and Deaf1, whereas the G-allele fails to bind these TFs [7]. Although these three TFs are typically regarded as repressors, the activity of Deaf1 at the 5-HT1A promoter exhibits opposing effects in presynaptic versus postsynaptic neuronal cells [7]. In the human prefrontal cortex, the G-allele demonstrates a lower expression level compared to the C-allele; however, this pattern does not hold true for the midbrain and hippocampus [8]. In a humanized mouse model, subjects with GG genotype exhibited higher levels of HTR1A mRNA and protein than those with CC genotype in a line-dependent manner [9]. Furthermore, in 5-HT1A-expressing neuronal cells, the G-allele was found to downregulate 5-HT1A expression [10]. These showed the complexity of regulatory variant function. Clinical researches on rs6295 had incongruous findings, raising the need for a SNP-based meta analysis. A single variant approach is a classical method to ascertain the relationship between a variant and putative phenotypes. Selective serotonin re-uptake Inhibitors (SSRIs) like fluoxetine, paroxetine, sertraline, citalopram, and fluvoxamine were included in this meta analysis, however, the result showed no significant correlation between this variation and antidepressant drug efficacy in MDD in the dominant model (CG vs CC), recessive model (GG vs CC), and combined dominant model (CG+GG vs CC). The 11 clinical studies collected in their meta analysis included multiple populations from over 10 countries with low to moderate heterogeneity and were scored 7-9 according to the Newcastle-Ottawa Scale (NOS), suggesting a result with higher confidence. The negative correlation might due to gene-gene interactions or gene-environment interactions in MDD and its treatment. A genome-wide linkage analysis for MDD showed that association of LHPP SNPs to MDD were depended on HTR1A -1019G allele [11]. Single variant approaches are limited by lower statistical detection power because most phenotypes result from the influence of many genetic variants in many genes and pathways[12]. This limitation is particularly pronounced in pharmacogenetics and multigenic diseases like MDD. Large-scale meta-analysis of GWAS might overcome this disadvantage. However, phenotype analysis involving rs6295 through GWAS is inherently limited due to its ambiguous nature (C/G). It is challenging to distinguish which complementary allele serves as the effect allele. Furthermore, the minor allele frequency (MAF) of rs6295 is G=0.483 in gnomAD and C=0.458 in 1000G, making it impossible to solve the problem by allele frequency. Ambiguous SNPs with allele frequencies close to 0.5 are usually removed in GWAS [13]. Therefore, a SNP meta-analysis remains a viable option for investigating rs6295. The clinical impacts of regulatory variants in monogenic Mendelian diseases have also been noticed. Many bioinformatic tools were developed to predict TF binding of regulatory variants like SNEEP [14]. Many of them use eQTL datasets as training and validation sets. In rs6295’s case, the variant had different functions in different brain regions, and showed negative significance to putative related phenotype. This suggested a limitation of using these tools to predict clinical candidate variants. However, there are few clinical curated regulatory variants databases available. There are only hundreds of regulatory variants in Clinvar database classified as pathogenic/likely pathogenic/benign/likely benign (data not shown). That’s not enough to feed a complex model. Overall, the negative relationship between the functional regulatory variant rs6295 and antidepressant response underscores the importance of re-evaluating the clinical significance of functional regulatory variants. Both positive and negative meta-analyses are essential for establishing robust relationships between polymorphisms and phenotypes. References [1] Wu HN, Zhu SY, Zhang LN, Shen BH, Xu LL. Association between 5-HTR1A gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis. World J Psychiatry 2024; 14(10): 1573-1582 [2]Lemonde S, Turecki G, Bakish D, Du L, Hrdina PD, Bown CD, Sequeira A, Kushwaha N, Morris SJ, Basak A, Ou XM, Albert PR. Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J Neurosci. 2003 Sep 24;23(25):8788-99 [3]Hernández-Díaz, Y., Tovilla-Zárate, C. A., Castillo-Avila, R. G., Juárez-Rojop, I. E., Genis-Mendoza, A. D., López-Narváez, M. L., Villar-Juárez, G. E., & González-Castro, T. B. (2023). Association between the HTR1A rs6295 gene polymorphism and suicidal behavior: an updated meta-analysis. European archives of psychiatry and clinical neuroscience, 273(1), 5–14 [4]Lemonde S, Du L, Bakish D, Hrdina P, Albert PR. Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response. Int J Neuropsychopharmacol. 2004 Dec;7(4):501-6 [5]Abell NS, DeGorter MK, Gloudemans MJ, Greenwald E, Smith KS, He Z, Montgomery SB. Multiple causal variants underlie genetic associations in humans. Science. 2022 Mar 18;375(6586):1247-1254 [6]Umans BD, Battle A, Gilad Y. Where Are the Disease-Associated eQTLs? Trends Genet. 2021 Feb;37(2):109-124 [7]Czesak M, Lemonde S, Peterson EA, Rogaeva A, Albert PR. Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism. J Neurosci. 2006 Feb 8;26(6):1864-71 [8]Donaldson ZR, le Francois B, Santos TL, Almli LM, Boldrini M, Champagne FA, Arango V, Mann JJ, Stockmeier CA, Galfalvy H, Albert PR, Ressler KJ, Hen R. The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription. Transl Psychiatry. 2016 Mar 1;6(3):e746 [9]Cunningham AM, Santos TL, Gutzeit VA, Hamilton H, Hen R, Donaldson ZR. Functional Interrogation of a Depression-Related Serotonergic Single Nucleotide Polymorphism, rs6295, Using a Humanized Mouse Model. ACS Chem Neurosci. 2019 Jul 17;10(7):3197-3206 [10]Czesak M, Lemonde S, Peterson EA, Rogaeva A, Albert PR. Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism. J Neurosci. 2006 Feb 8;26(6):1864-71 [11]Neff CD, Abkevich V, Packer JC, Chen Y, Potter J, Riley R, Davenport C, DeGrado Warren J, Jammulapati S, Bhathena A, Choi WS, Kroeger PE, Metzger RE, Gutin A, Skolnick MH, Shattuck D, Katz DA. Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression. Mol Psychiatry. 2009 Jun;14(6):621-30 [12]Defo J, Awany D, Ramesar R. From SNP to pathway-based GWAS meta-analysis: do current meta-analysis approaches resolve power and replication in genetic association studies? Brief Bioinform. 2023 Jan 19;24(1):bbac600 [13]Ndong Sima, C.A.A., Step, K., Swart, Y. et al. Methodologies underpinning polygenic risk scores estimation: a comprehensive overview. Hum. Genet. 143, 1265–1280 (2024) [14]Baumgarten N, Rumpf L, Kessler T, Schulz MH. A statistical approach for identifying single nucleotide variants that affect transcription factor binding. iScience. 2024 Apr 18;27(5):109765 " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Wu HN, Zhu SY, Zhang LN, Shen BH, Xu LL. Association between <i>5-HTR1A</i> gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder: A meta-analysis. <em>World J Psychiatry</em> 2024; 14(10): 1573-1582 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 11 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i39/4295.htm" class="author-comment" target="_blank"> "This study provides valuable insights into the treatment of Helicobacter pylori infection. The comparison between low - dose and ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i39/4295.htm" class="author-comment" target="_blank"> "This study provides valuable insights into the treatment of Helicobacter pylori infection. The comparison between low - dose and standard - dose tetracycline in combination with amoxicillin quadruple therapy is well - designed and the results are significant.The research is comprehensive, considering factors such as eradication rates and adverse events. It offers a potential alternative treatment option with better safety profiles, which is beneficial for patients. Also, there still exist some questions to be considered. 1. Regarding the article structure • When introducing the research background, various antibiotic resistance rates against Helicobacter pylori are listed in detail. However, could this part be presented more concisely and focused more on the resistance situations of tetracycline and amoxicillin directly related to this study? • In the research methods section, could the description of the patient inclusion and exclusion criteria be more focused on the key points and avoid being interfered by too many irrelevant details? For example, the emphasis could be placed on those factors that may have a crucial impact on the research results. • In the results presentation part, could the comparison results of different groups be shown in a clearer structure? For example, the main results of all groups could be presented first, and then the situations of each subgroup (such as the primary treatment group and the rescue treatment group) could be elaborated in detail respectively, which would make it easier for readers to grasp the overall logic. 2. Regarding the article content • When discussing the advantages of low - dose tetracycline, besides comparing the eradication rates and adverse events with the standard - dose tetracycline, could the possible mechanism of action be further explored? This would help readers understand the research results more in - depth. • Some factors affecting the Helicobacter pylori eradication rate are mentioned in the article, such as patient compliance, smoking history, etc. However, could a more in - depth analysis of the interactions between these factors be carried out? For example, does smoking affect the eradication rate by influencing compliance? • Regarding the content of the gut microbiota, although it is mentioned in the limitations that the impact of the low - dose tetracycline regimen on the gut microbiota has not been studied, could the future research directions be more specifically elaborated on how to design relevant studies to explore this issue? 3. Regarding the charts • There is a lot of data in the tables in the article, and some abbreviations in the tables may confuse readers. Could more detailed explanations be given below the tables or where the abbreviations first appear? • Could the titles of the charts more clearly reflect the core content of the charts? For example, some chart titles only simply describe the variables involved in the charts without highlighting the main conclusions or trends. • Could some more charts be considered to present the key information in the research more intuitively? For example, charts could be used to show the occurrence trends of adverse events in different tetracycline dose groups during the treatment process, or to present the relative magnitudes of the impacts of different factors on the eradication rate. 4.Further study • It would be interesting to see if the results hold true in different populations and geographical regions. • The study could have included a more detailed analysis of the long - term effectiveness and potential recurrence of H. pylori infection after treatment. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Zhao YR, Wang XJ, Zhu MJ, Chen AL, Zhang D, Du Q, Kim JJ, Hu WL. Efficacy and safety of low-dose tetracycline, amoxicillin quadruple therapy in <i>Helicobacter pylori</i> infection: A retrospective single center study. <em>World J Gastroenterol</em> 2024; 30(39): 4295-4304 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 12 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5204/full/v16/i11/4468.htm" class="author-comment" target="_blank"> "This paper conducts an in-depth study on the effects of invigorating-spleen and anticancer prescription (ISAP) in a mice model of ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5204/full/v16/i11/4468.htm" class="author-comment" target="_blank"> "This paper conducts an in-depth study on the effects of invigorating-spleen and anticancer prescription (ISAP) in a mice model of colon cancer, providing valuable experimental data and analysis. Here are some of my comments on the paper: 1. Clear research background: The paper begins with a detailed introduction to the epidemiological data of colon cancer, emphasizing the severity of the disease and the limitations of existing treatment methods, providing a good background for the necessity of the study. 2. Reasonable experimental design: The study established a mice model of colon cancer and divided it into several experimental groups (including a control group and groups with different doses of ISAP), a design that effectively compares the effects of different doses of ISAP on tumor suppression. 3. Detailed data analysis: The paper provides detailed data on the measurement of mice weight, tumor inhibition rate, and related protein expression levels, with clear and understandable results. These data provide empirical support for the anti-tumor mechanism of ISAP. 4. In-depth mechanism exploration: By analyzing key proteins in the ERK/MAPK signaling pathway, the paper explores the potential mechanism of action of ISAP, providing new ideas for subsequent research. 5. Clinical significance: Although the study has achieved positive results in the mice model, the effectiveness and safety of ISAP still need to be verified in clinical trials. This point can be further emphasized in the discussion section. 6. Language and structure: The language of the paper is relatively fluent, with a clear structure, making it easy for readers to understand. However, the explanation of some professional terms could be more detailed, for the understanding of non-professional readers. Overall, this paper provides strong support for the potential of ISAP in the treatment of colon cancer, looking forward to seeing more clinical research results in the future. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Wang W, Wang J, Ren XX, Yue HL, Li Z. Effects of invigorating-spleen and anticancer prescription on extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway in colon cancer mice model. <em>World J Gastrointest Oncol</em> 2024; 16(11): 4468-4476 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 13 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-0210/full/v16/i10/873.htm" class="author-comment" target="_blank"> "The original article by Wang FD et al., "Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-0210/full/v16/i10/873.htm" class="author-comment" target="_blank"> "The original article by Wang FD et al., "Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell extracellular vesicles to alleviate myocardial ischaemia-reperfusion injury via TXNIP regulation," is very good. GABA-induced miR-21-5p-loaded EVs utilise a unique mechanism to lessen myocardial ischaemia-reperfusion injury (MIRI) and present a novel method for managing MIRI through oxidative stress modulation. The study reported that miR-21-5p exerts its effects through a direct interaction with TXNIP in cardiomyocytes, thereby triggering oxidative stress and elucidating related molecular mechanisms. Furthermore, this work systematically employs in vivo, in vitro, and a variety of imaging methods with gene knockout models to provide comprehensive methodological proofs. Considering myocardial ischaemia is a common clinical condition, this study has high translational relevance. But there are few queries: The experiment only evaluates its EV source in inguinal ADSCs and could miss other potential beneficial configurations of EV. It is still unclear whether these short-term therapeutic effects are sustainable or if they interfere with repeated dosing against MIRI, despite the study's lack of a long-term assessment. The process of producing, standardizing, and ensuring the safety of EVs for human use could potentially complicate the clinical translation of the latter strategy. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Wang FD, Ding Y, Zhou JH, Zhou E, Zhang TT, Fan YQ, He Q, Zhang ZQ, Mao CY, Zhang JF, Zhou J. Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell extracellular vesicles to alleviate myocardial ischemia-reperfusion injury <i>via</i> TXNIP regulation. <em>World J Stem Cells</em> 2024; 16(10): 873-895 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 14 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2218-5836/full/v15/i10/950.htm" class="author-comment" target="_blank"> "The theme of this article is very practical and a common problem that troubles elderly women, and the conclusion is very meaningful. ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2218-5836/full/v15/i10/950.htm" class="author-comment" target="_blank"> "The theme of this article is very practical and a common problem that troubles elderly women, and the conclusion is very meaningful. It can help alleviate the pain of many women. The abundant scientific data and clear images fully demonstrate the role of exercise therapy, providing methods and ideas for further research.As a reader, I really enjoy this article as it allows me to quickly gain knowledge about this topic. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Dai ZQ, Gong XY, Zhang R, Jin MQ, Lu W, Wen W, Chen J, Lu FJ, Yang YF, Wang L, He XJ. Research trends in exercise therapy for the treatment of pain in postmenopausal osteoporosis over the past decade: A bibliometric analysis. <em>World J Orthop</em> 2024; 15(10): 950-964 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 15 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i38/4242.htm" class="author-comment" target="_blank"> "This article is interesting, but does not provide any novelties nor scientific approaches in diagnostics of IBD, it is based on ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1007-9327/full/v30/i38/4242.htm" class="author-comment" target="_blank"> "This article is interesting, but does not provide any novelties nor scientific approaches in diagnostics of IBD, it is based on "defending" physicians and minorizing their role in detecting Crohn's disease. I could agree with main conclusion of this article, that providing a diagnose of Crohn's disease is multifactorial, and it depends not only on physicians but on patients itself, time frame, diagnostic abilities. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Zeng Y, Zhang JW, Yang J. Physician-dependent diagnosis delay in Crohn's disease: A pseudo-proposition or not? <em>World J Gastroenterol</em> 2024; 30(38): 4242-4245 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 16 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i10/2058.htm" class="author-comment" target="_blank"> "1. This study lacks an ethics statement. It is advisable to include an ethics statement within the methods section. 2. The ROC curve ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-9358/full/v15/i10/2058.htm" class="author-comment" target="_blank"> "1. This study lacks an ethics statement. It is advisable to include an ethics statement within the methods section. 2. The ROC curve presented in the results suggests that the sample size may be relatively insufficient. It is recommended that researchers increase the sample size in further studies and conduct prospective investigations to validate these findings. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Lin BS, Liu ZG, Chen DR, Yang YL, Yang DZ, Yan JH, Zeng LY, Yang XB, Xu W. Relationship between hemoglobin glycation index and risk of hypoglycemia in type 2 diabetes with time-in-range in target. <em>World J Diabetes</em> 2024; 15(10): 2058-2069 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 17 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2218-4333/full/v15/i11/1428.htm" class="author-comment" target="_blank"> "Title: A Study on the Deterioration of Intracranial Epidermoid Cysts through Whole Exome Sequencing Dear Editors and Authors, First ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2218-4333/full/v15/i11/1428.htm" class="author-comment" target="_blank"> "Title: A Study on the Deterioration of Intracranial Epidermoid Cysts through Whole Exome Sequencing Dear Editors and Authors, First and foremost, I would like to congratulate the authors on the publication of this high-quality case report on the malignant transformation of intracranial epidermoid cysts (IEC) into squamous cell carcinoma (SCC) in the "World Journal of Clinical Oncology." This study not only provides valuable insights into the molecular mechanisms underlying the transformation of IEC to SCC but also reveals two potential disease-related gene mutations: GJB2 (c.257C>T) and TLR2 (c.1039A>G) through whole exome sequencing (WES). Comment Content: Innovation and Importance of the Study: The innovation of this study lies in providing the first clinical evidence for the potential role of GJB2 and TLR2 in the development and treatment of IEC. This is significant for guiding future research directions and potential therapeutic targets. Rigorous Study Design: The authors have employed WES technology, which is efficient and cost-effective for processing large amounts of data quickly. This method is highly applicable for screening genetic variants related to rare and complex diseases, demonstrating the rigor and forward-thinking of the study design. Detailed Case Report: The article provides a very detailed description of the case, including the patient's clinical symptoms, medical history, laboratory test results, and imaging examination results. These details help readers to fully understand the case and provide valuable data for future research. In-Depth Analysis of Genetic Variants: The authors not only identified two risk variants but also conducted an in-depth analysis of their impact on protein structure and function. This in-depth analysis helps to understand how these variants affect the occurrence and development of the disease. Comprehensive Treatment and Follow-Up: The article describes the patient's treatment process and follow-up results in detail, providing valuable references for clinical doctors and demonstrating the effectiveness of comprehensive treatment in controlling the condition. Suggestions for Improvement: Increase the Sample Size: Although this is a report on a rare case, increasing the sample size will help to verify the association between these gene mutations and the deterioration of IEC and improve the generalizability and reliability of the study's results. Functional Validation Experiments: The authors mentioned plans for functional validation experiments in future studies. These experiments will help further confirm the role of GJB2 and TLR2 in the development of IEC and how these mutations affect protein function. Long-Term Follow-Up Data: Long-term follow-up data will help assess the long-term effects of treatment and the patient's quality of life, which is crucial for evaluating treatment outcomes and formulating treatment guidelines. Conclusion: This article is an important contribution to the study of the mechanisms underlying the malignant transformation of IEC. It not only enhances our understanding of the genetic basis of this rare disease but also provides new ideas for future treatments. The authors' work is commendable, and I look forward to their future research bringing more breakthrough " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Song ZN, Cheng Y, Wang DD, Li MJ, Zhao XR, Li FW, Liu Z, Zhu XR, Jia XD, Wang YF, Liang FF. Whole exome sequencing identifies risk variants associated with intracranial epidermoid cyst deterioration: A case report. <em>World J Clin Oncol</em> 2024; 15(11): 1428-1434 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 18 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/2218-4333/full/v15/i11/1404.htm" class="author-comment" target="_blank"> "The combination of Astragalus polysaccharide and gimeracil oteracil potassium capsule (S-1) in the treatment of pancreatic cancer ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/2218-4333/full/v15/i11/1404.htm" class="author-comment" target="_blank"> "The combination of Astragalus polysaccharide and gimeracil oteracil potassium capsule (S-1) in the treatment of pancreatic cancer can effectively improve the efficacy, reduce side effects, and increase long-term survival rates, which has significant clinical value.In the future, we can further validate its efficacy by conducting prospective, large-scale, multi-center studies and provide more guiding recommendations for clinical practice. " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Li GY, Jiang J. Recent efficacy and long-term survival of <i>Astragalus</i> polysaccharide combined with gemcitabine and S-1 in pancreatic cancer. <em>World J Clin Oncol</em> 2024; 15(11): 1404-1411 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 19 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i9/1269.htm" class="author-comment" target="_blank"> "Commentary: Predictors of survival in autoimmune liver disease overlap syndromes Jian-Guo Zhang,Biao Wen Jian-Guo Zhang,Biao ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-5182/full/v16/i9/1269.htm" class="author-comment" target="_blank"> "Commentary: Predictors of survival in autoimmune liver disease overlap syndromes Jian-Guo Zhang,Biao Wen Jian-Guo Zhang,Biao Wen,Department of Gastroenterology, The First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, Sichuan Province, China Author contributions:Jian-Guo Zhang wrote the original draft; Biao Wen contributed to conceptualization, writing, reviewing and editing; Jian-Guo Zhang and Biao Wen participated in drafting the manuscript; and all authors have read and approved the final version of the manuscript. ORCID number：0000-0001-5226-5981 Corresponding author:Biao Wen,MD, PhD,Assistant Professor,Department of Gastroenterology, The First Affiliated Hospital of Chengdu Medical College,No. 312, Middle Section of Baoguang Avenue, Xindu District, Chengdu 610000, Sichuan Province, China. 820695761@qq.com We perused the article authored by Jayabalan et al[1]with considerable interest and extend our congratulations to the authors for their commendable endeavor. The authors have reported a prospective investigation into the predictors of survival in patients with autoimmune liver disease overlap syndromes (AILDOS)[1]. The study's conclusion suggests that the LOS holds potential as a predictive tool for liver-related mortality in individuals with autoimmune hepatitis and primary biliary cholangitis overlap (AIH-PBC)[1]. However, several aspects of this study merit further scrutiny and discussion. Firstly, a critical exclusion criterion for the study was the prior performance of a liver transplant prior to enrollment[1]. Upon consideration, we postulated the possibility that a portion of the enrolled patients might harbor coexisting liver pathology stemming from disparate causes (including, but not limited to, alcoholic liver disease or viral hepatitis), which could introduce bias and complicate the interpretation of our results. Therefore, we advised the authors to implement rigorous exclusion criteria for such patients to uphold the accuracy and reliability of our findings. Secondly, the diagnoses of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC) were established in accordance with the criteria stipulated by the International Autoimmune Hepatitis Group, the European Association for the Study of the Liver Clinical Practice Guidelines, and the American College of Gastroenterology Clinical Guidelines, respectively[1-4]. It is noteworthy that these diagnostic criteria originate from disparate geographical regions, and the progression of research concerning each disease varies across these regions. Consequently, such variability may potentially impact the precision of the study's findings. In light of this, we propose that the authors consider adopting diagnostic criteria from a uniform geographical region. Therefore, we recommend the uniform application of diagnostic guidelines or consensus recommendations established by reputable institutions in the United States for the purposes of disease ascertainment. Such standardization is poised to substantially elevate the reliability and validity of the research findings, thereby reinforcing the scientific rigor and credibility of the conducted studies.[4-6]. Thirdly, the authors confined their analysis solely to the occurrence or absence of liver-related mortality, while neglecting to account for the medical interventions undergone by the patients during the follow-up period[1]. It is imperative to elucidate the potential impact of these interventions on the study's findings. A comprehensive assessment of the medical interventions received by the patients is crucial for ensuring the accuracy and robustness of the study's conclusions. Ultimately, as highlighted by the authors, the primary limitation of this study is the relatively modest sample size[1]. Consequently, it is imperative that future research endeavors incorporate larger sample populations and adopt a multicenter design to validate the findings of the present study and further elucidate the pertinence to patients with AIH-PSC. Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported. REFERENCES 1 Jayabalan D, Huang Y, Calzadilla-Bertot L, Janjua M, de Boer B, Joseph J, Cheng W, Hazeldine S, Smith BW, MacQuillan GC, Wallace MC, Garas G, Adams LA, Jeffrey GP. Predictors of survival in autoimmune liver disease overlap syndromes. World J Hepatol 2024; 16: 1269-1277. [PMID:39351512 DOI: 10.4254/wjh.v16.i9.1269] 2 European Association for the Study of the Liver. EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. J Hepatol 2017; 67: 145-172. [PMID: 28427765 DOI: 10.1016/j.jhep.2017.03.022] 3 Czaja AJ. Diagnosis and Management of Autoimmune Hepatitis: Current Status and Future Directions. Gut Liver 2016; 10: 177-203. [PMID:26934884 DOI: 10.5009/gnl15352] 4 Lindor KD, Kowdley KV, Harrison ME. ACG Clinical Guideline: Primary Sclerosing Cholangitis. Am J Gastroenterol 2015; 110: 646-659, 660. [PMID: 25869391 DOI: 10.1038/ajg.2015.112] 5 Mack CL, Adams D, Assis DN, Kerkar N, Manns MP, Mayo MJ, Vierling JM, Alsawas M, Murad MH, Czaja AJ. Diagnosis and Management of Autoimmune Hepatitis in Adults and Children: 2019 Practice Guidance and Guidelines From the American Association for the Study of Liver Diseases. Hepatology 2020; 72: 671-722. [PMID: 31863477 DOI: 10.1002/hep.31065] 6 Lindor KD, Bowlus CL, Boyer J, Levy C, Mayo M. Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases. Hepatology 2019; 69: 394-419. [PMID:30070375 DOI: 10.1002/hep.30145] " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Jayabalan D, Huang Y, Calzadilla-Bertot L, Janjua M, de Boer B, Joseph J, Cheng W, Hazeldine S, Smith BW, MacQuillan GC, Wallace MC, Garas G, Adams LA, Jeffrey GP. Predictors of survival in autoimmune liver disease overlap syndromes. <em>World J Hepatol</em> 2024; 16(9): 1269-1277 </div> </div> </div> <div class="articleitem cl"> <div class="num fl"> 20 </div> <div class="item fl"> <div class="title authorreview-cropped inline"> <a href="https://www.wjgnet.com/1948-0210/full/v16/i9/827.htm" class="author-comment" target="_blank"> "Comment on “Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool” Shuang Wu, Hong Cai* ..." </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-cropped').toggleClass('inline').next('.authorreview-full').toggleClass('inline'); return false;">  [Read more] </a> </div> <div class="title authorreview-full"> <a href="https://www.wjgnet.com/1948-0210/full/v16/i9/827.htm" class="author-comment" target="_blank"> "Comment on “Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool” Shuang Wu, Hong Cai* Corresponding author: Hong Cai, Department of Dermatology, Air Force Medical Center, PLA, Beijing, 100142, P. R. China. ch1031@163.com Affiliation: Department of Dermatology, Department of Dermatology, Air Force Medical Center, PLA. No.30 of Fucheng Road. Beijing 100142, China. Key Words: Bibliometric analysis; Mesenchymal stem cells; Wound healing; To the Editor: We read the editorial by Vera et al [1]with great interest. In this editorial, the author conducted a keyword comparison and analysis of basic research published in BPG from 2023 to 2024, utilizing the bibliometric analysis approach of Shi et al[2]. This emphasizes the effectiveness of bibliometric analysis as a research tool. Additionally, the author examined several other articles on BPG, excluding WJSC, that were not included in Shi et al.'s bibliometric analysis. The findings indicate that although the application of bibliometric analysis in basic research remains limited, it can help identify key research directions and challenges in the field, advance the application of MSCs in the treatment of chronic wounds, and facilitate comprehensive analysis of related literature to better understand the current state of research and future development potential. First, the author conducted a keyword analysis of basic research on diabetic foot published in BPG, utilizing the bibliometric analysis by Shi et al. to highlight the value of bibliometric analysis in this field, which can provide clear directions for research hotspots. However, while Shi et al. used the Web of Science Core Collection database, the author of this article relied solely on the database affiliated with BPG for keyword comparisons. This discrepancy might introduce potential biases in the analysis results due to differences in research directions and acceptance criteria between journals[3,4]. Second, the author also pointed out limitations in Shi et al.'s bibliometric analysis: the analysis primarily focused on journals related to diabetic foot, while literature from other relevant fields was excluded from the search. This implies that some articles pertaining to stem cell therapy for diabetic foot may not have been incorporated, underscoring the necessity of expanding the search scope in future bibliometric analyses. Third, the author specifically analyzed literature on stem cell therapy for diabetic foot published in BPG during 2023-2024, while Shi et al.'s bibliometric analysis covered related literature from 2000 to 2023, thereby including a broader time span and a more extensive range of keywords. As basic research evolves, there may be past hotspot keywords that are now rarely used, or new research hotspots published in BPG that were not included in Shi et al.'s bibliometric analysis[5]. In summary, this is an editorial that employs bibliometric analysis to conduct a keyword analysis of relevant papers published in BPG from 2023 to 2024, elucidating the role of bibliometric analysis in basic research. If the analysis were to consider the acceptance criteria of different journals and the issue of timeliness more extensively, the conclusions could potentially be more compelling. References 1 Voinova VV, Vasina DV, Bonartsev AP. Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool. World J Stem Cells 2024; 16: 827–831. [PMID: 39351262 DOI: 10.4252/wjsc.v16.i9.827] 2 Shi H-S, Yuan X, Wu F-F, Li X-Y, Fan W-J, Yang X, Hu X-M, Liu G-B. Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives. World J Stem Cells 2024; 16: 33–53. [PMID: 38292441 DOI: 10.4252/wjsc.v16.i1.33] 3 Frank E. Authors’ Criteria for Selecting Journals. JAMA 1994; 272: 163–164. [DOI: 10.1001/jama.1994.03520020089026] 4 Garfield E. The History and Meaning of the Journal Impact Factor. JAMA 2006; 295: 90–93. [DOI: 10.1001/jama.295.1.90] 5 Tversky A, Kahneman D. Judgment under Uncertainty: Heuristics and Biases. Science 1974; 185: 1124–1131. [DOI: 10.1126/science.185.4157.1124] " </a> <a href="javascript:void(0);" class="readmore" onclick="$(this).parents('.authorreview-full').toggleClass('inline').prev('.authorreview-cropped').toggleClass('inline'); return false;">  [Collapse] </a> </div> <div class="count"> Voinova VV, Vasina DV, Bonartsev AP. Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool. <em>World J Stem Cells</em> 2024; 16(9): 827-831 </div> </div> </div> <div class="more"> <span>873 items</span>  <a href="https://www.f6publishing.com/ReaderComments" target="_blank">Read more >></a> </div> </div> </div> </div> </div> <div class="down cl"> <div class="helpdesk cl"> <a href="https://www.f6publishing.com/HelpDesk" target="_blank">Write to the Help Desk</a> </div> <div class="subfooter cl"> <ul> <li> <b>ALL AUTHOR RESOURCES</b> </li> <li> <a href="https://www.wjgnet.com/bpg/GerInfo/312" target="_blank">Appeals and Complaints</a> </li> <li> <a 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