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Proteomics Consortium - SomaLogic
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menu-item-6067"><a href="#">Global</a></li> </ul> </div> </div> </div> </div> </div> </header> <main class="page-content"> <div class="hero" style="background-image: url(https://somalogic.com/wp-content/uploads/2023/10/consortiumPage_Hero-scaled.jpg);height: 670px;" title="Abstract image of connected proteins on blue hero background"> <div class="container"> <div class="grid"> <div class="cell-md-9"> <p class="breadcrumbs"><a href="/">Home</a> / Education / Biobank and Cohort Research / <span class="blue">Proteomics Consortium</span></p> <h1>SomaScan®<br /> Proteomics Consortium</h1> <p>Advancing precision medicine research through worldwide sharing of human proteomic data</p> </div> </div> </div> </div><div class="wrap white " id="wrap_0" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class="a-center mb-60"><h2>Advancing the power of precision medicine and population proteomics research through global collaboration and data sharing</h2> </div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mb-60"><p>The SomaScan Proteomics Consortium was founded by Russell Bowler, MD, PhD, to enable researchers to increase the power of their studies by leveraging high-plex proteomic profiling with the SomaScan® Assay across diverse populations worldwide, for more powerful biomarker discovery and deeper insights into human biology. Members are committed to sharing data for the purpose of increasing efficiency and efficacy, as well as for fostering discussions about the development and pursuit of new studies and research directions.</p> <p>SomaLogic is honored to support the consortium as an independent and open exchange of ideas, knowledge, and results, in order to accelerate the study of disease and human biology.</p> <p style="margin-top: 15px">For general inquiries or to join the consortium, please contact<a href="/cdn-cgi/l/email-protection#82e0edf5eee7f0f0c2e1e1e4acedf0e5"> Russell Bowler, MD, PhD.</a></p> </div> </div><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><div style="position:relative;width:auto;padding:0 0 41.36%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-659e062c3b7f0" data-aspectRatio="2.4178" data-mobile-aspectRatio="0.8308"><iframe title="BlockQuote - Bowler" allowfullscreen src="https://view.ceros.com/somalogic/blockquote-bowler" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div></div> </div> </div><div class="wrap grey " id="wrap_1" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mb-30"><h3>Consortium Principles</h3> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class=""><ul class="blue-dot"> <li>Advance knowledge of the proteome to improve understanding of disease etiology, diagnosis and prognosis</li> <li>Promote opportunities to collaborate and share results</li> <li>Adopt a distributive analysis model</li> </ul> </div> </div><div class="text-block cell-md-6 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class=""><ul class="blue-dot"> <li>Preserve governance of cohort data with cohort Principal Investigators</li> <li>Support the development of early-career researchers</li> <li>Raise common funds through grants and donations by sharing analyses and preliminary data</li> </ul> </div> </div></div> </div> </div><div class="wrap white " id="wrap_2" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="mb-60 a-center"><h2>Current cohorts used by consortium members in proteomics research using the SomaScan Assay</h2> <p>To learn more about the biobanks and prospective cohort studies listed, please click “View now” next to each.</p> <div class="wpdt-c wdt-skin-light"> <input 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none; " data-described-by='table_2_desc' data-wpdatatable_id="26"> <!-- Table header --> <thead> <tr> <th class=" wdtheader sort numdata integer " style=""> Number</th> <th data-class="expand" class=" wdtheader sort " style=""> Cohort Name</th> <th data-hide="phone" class="phone wdtheader sort " style=""> Cohort Acronym</th> <th class=" wdtheader sort " style=""> Population</th> <th class=" wdtheader " style=""> Website</th> <th class=" wdtheader sort " style=""> Research Contact</th> </tr> </thead> <!-- /Table header --> <!-- Table body --> <tbody> <!-- Table body --> <div data-id="26" class="wdt-timeline-item wdt-timeline-table_2" style=""> <div class="wdt-table-loader"> <div class="wdt-table-loader-row wdt-table-loader-header"> <div class="wdt-table-loader-header-cell wdt-animated-background"></div> <div class="wdt-table-loader-header-cell wdt-animated-background"></div> <div class="wdt-table-loader-header-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> <div class="wdt-table-loader-row"> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> <div class="wdt-table-loader-cell wdt-animated-background"></div> </div> </div> </div><!-- /Table body --> <tr id="table_26_row_0" data-row-index="0"> <td style="">1</td> <td style="">Atherosclerosis Risk in Communities</td> <td style="">ARIC</td> <td style="">(USA) Black and white adults, originally aged 45-64 years</td> <td style=""><a href='https://aric.cscc.unc.edu/aric9/' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style=""></td> </tr> <tr id="table_26_row_1" data-row-index="1"> <td style="">2</td> <td style="">Baltimore Longitudinal Study of Aging</td> <td style="">BLSA</td> <td style="">(USA) Population of varied ages studied longitudinally</td> <td style=""><a href='https://www.nia.nih.gov/research/labs/blsa/about' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style=""></td> </tr> <tr id="table_26_row_2" data-row-index="2"> <td style="">3</td> <td style="">Cardiovascular Health Study</td> <td style="">CHS</td> <td style="">(USA) Men and women, 65 years and older</td> <td style=""><a href='https://www.nhlbi.nih.gov/science/cardiovascular-health-study-chs' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style=""></td> </tr> <tr id="table_26_row_3" data-row-index="3"> <td style="">4</td> <td style="">Chronic Obstructive Pulmonary Disease</td> <td style="">COPDGene</td> <td style="">(USA) Older current and former smokers</td> <td style=""><a href='https://www.COPDGene.org' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Russel Bowler</td> </tr> <tr id="table_26_row_4" data-row-index="4"> <td style="">5</td> <td style="">Chronic Renal Insufficiency Cohort</td> <td style="">CRIC</td> <td style="">(USA) Population with kidney disease</td> <td style=""><a href='https://www.clinicaltrials.gov/show/NCT00304148' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style=""></td> </tr> <tr id="table_26_row_5" data-row-index="5"> <td style="">6</td> <td style="">Exenatide Study of Cardiovascular Event Lowering</td> <td style="">EXSCEL</td> <td style="">(International) Patients with diabetes and high risk of cardiovascular disease (CVD)</td> <td style=""><a href='https://www.clinicaltrials.gov/ct2/show/NCT01144338' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Svati Shah</td> </tr> <tr id="table_26_row_6" data-row-index="6"> <td style="">7</td> <td style="">Framingham Heart Study</td> <td style="">FHS</td> <td style="">(USA) New England population</td> <td style=""><a href='https://www.framinghamheartstudy.org' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Debby Ngo</td> </tr> <tr id="table_26_row_7" data-row-index="7"> <td style="">8</td> <td style="">Honolulu Heart Program</td> <td style="">HHP</td> <td style="">(USA) Japanese Americans living in Hawaii</td> <td style=""><a href='https://biolincc.nhlbi.nih.gov/studies/hhp/' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style=""></td> </tr> <tr id="table_26_row_8" data-row-index="8"> <td style="">9</td> <td style="">Jackson Heart Study</td> <td style="">JHS</td> <td style="">(USA) Mississippi African American population</td> <td style=""><a href='https://www.jacksonheartstudy.org' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Debby Ngo</td> </tr> <tr id="table_26_row_9" data-row-index="9"> <td style="">10</td> <td style="">Cooperative Health Research in the Augsburg Region</td> <td style="">KORA</td> <td style="">(Germany) Southern Germany population</td> <td style=""><a href='https://www.helmholtz-muenchen.de' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Claudia Flexeder</td> </tr> <tr id="table_26_row_10" data-row-index="10"> <td style="">11</td> <td style="">Lovelace Smokers Cohort</td> <td style="">LSC</td> <td style="">(USA) Southwest community, current and former smokers</td> <td style=""></td> <td style="">Yohannes Tesfaigzi</td> </tr> <tr id="table_26_row_11" data-row-index="11"> <td style="">12</td> <td style="">Multi-Ethnic Study of Atherosclerosis</td> <td style="">MESA</td> <td style="">(USA) Multi-ethnic population</td> <td style=""><a href='https://www.mesa-nhlbi.org' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Ani Manichaikul</td> </tr> <tr id="table_26_row_12" data-row-index="12"> <td style="">13</td> <td style="">SubPopulations and InteRmediate Outcome Measures in COPD Study</td> <td style="">SPIROMICS</td> <td style="">(USA) Older current and former smokers</td> <td style=""><a href='https://www2.cscc.unc.edu/spiromics/' rel='' target='_blank'><button class='SL-btn'>View now</button></a></td> <td style="">Russel Bowler</td> </tr> </tbody> <!-- /Table body --> <!-- Table footer --> <!-- /Table footer --> </table> </div><style> table.wpDataTable { table-layout: fixed !important; } table.wpDataTable td, table.wpDataTable th { white-space: normal !important; } </style> <style> /* table font color */ .wpdt-c.wpDataTablesWrapper table.wpdtSimpleTable thead th, .wpdt-c.wpDataTablesWrapper table.wpdtSimpleTable tbody td, .wpdt-c .wpDataTablesWrapper table.wpDataTable thead th, .wpdt-c .wpDataTablesWrapper table.wpDataTable tbody td, .wpdt-c .wpDataTablesWrapper table.wpDataTable tfoot td { color: #000000 !important; } /* table font color */ .wpdt-c.wpDataTablesWrapper table.wpdtSimpleTable, .wpdt-c .wpDataTablesWrapper table.wpDataTable { font-family: Arial, Helvetica, sans-serif !important; } /* table font size */ 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class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mb-60"><h2>Data tips and resources</h2> </div> </div><div class="tabs-block consortium-tabs cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0"> <div class="tabs"> <div class="tabs-nav"> <div data-id="tab_0" class="active" data-text="What is an ADAT file?">What is an ADAT file?</div><div data-id="tab_1" data-text="What is a data repository?">What is a data repository?</div><div data-id="tab_2" data-text="Resources for data repositories">Resources for data repositories</div><div data-id="tab_3" data-text="About the NIH requirement to upload data">About the NIH requirement to upload data</div><div data-id="tab_4" data-text="How to upload SomaScan data to public repositories">How to upload SomaScan data to public repositories</div><div data-id="tab_5" data-text="Assistance: SomaLogic Technical Support">Assistance: SomaLogic Technical Support</div> </div> <div data-id="tab_0" class="tab-title active" data-text="What is an ADAT file?">What is an ADAT file?</div><div class="tab active" id="tab_0"><div class="icon align-center"> <p style="margin: 0px;"><img fetchpriority="high" decoding="async" class="aligncenter wp-image-5925 size-medium" src="https://somalogic.com/wp-content/uploads/2023/10/gitHubPreviewWhite-300x225.png" alt="Preview image of SomaLogic GitHub repository" width="300" height="225" srcset="https://somalogic.com/wp-content/uploads/2023/10/gitHubPreviewWhite-300x225.png 300w, https://somalogic.com/wp-content/uploads/2023/10/gitHubPreviewWhite.png 400w" sizes="(max-width: 300px) 100vw, 300px" /></p> <div class="pl-40"> <p>The ADAT file format is a Soma Logic-specific, tab-delimited text file designed to store Somascan study data. This format is intended to be flexible and self-explanatory. When sample analysis is completed, SomaLogic normalizes the data to ensure data quality and then creates an ADAT file for delivery of results to the researcher.</p> <p>If you have questions or need assistance with ADAT files, please email SomaLogic Technical Support <a href="/cdn-cgi/l/email-protection#2b5f4e4843585e5b5b44595f6b5844464a47444c424805484446">here</a>.</p> </div> </div> </div><div data-id="tab_1" class="tab-title " data-text="What is a data repository?">What is a data repository?</div><div class="tab " id="tab_1"><div class="icon align-center"> <p style="margin: 0px;"><img decoding="async" class="aligncenter wp-image-5926 size-medium" src="https://somalogic.com/wp-content/uploads/2023/10/ThreeLogos_v2-300x243.png" alt="Image of three logos - NIH, PRIDE, Proteome Xchange" width="300" height="243" srcset="https://somalogic.com/wp-content/uploads/2023/10/ThreeLogos_v2-300x243.png 300w, https://somalogic.com/wp-content/uploads/2023/10/ThreeLogos_v2.png 345w" sizes="(max-width: 300px) 100vw, 300px" /></p> <div class="pl-40"> <p>A data repository serves as a structured digital storage facility, often resembling databases or data lakes, where research data and analytical resources are systematically organized and made accessible in accordance with FAIR (Findable, Accessible, Interoperable, and Reusable) standards. Data repositories exist in two primary forms: open access and closed access.</p> <p><a href="https://www.nature.com/sdata/policies/repositories" target="_blank" rel="noopener">Learn why</a> researchers are increasingly encouraged – or required – to upload data to a repository before publishing their findings.</p> </div> </div> </div><div data-id="tab_2" class="tab-title " data-text="Resources for data repositories">Resources for data repositories</div><div class="tab " id="tab_2"><div class="icon align-center"> <p style="margin: 0px;"><img decoding="async" class="aligncenter wp-image-5927 size-medium" src="https://somalogic.com/wp-content/uploads/2023/10/adatFilePreview_White-300x245.png" alt="SomaLogic ADAT file type preview image" width="300" height="245" srcset="https://somalogic.com/wp-content/uploads/2023/10/adatFilePreview_White-300x245.png 300w, https://somalogic.com/wp-content/uploads/2023/10/adatFilePreview_White.png 400w" sizes="(max-width: 300px) 100vw, 300px" /></p> <div class="pl-40"> <p>Data repositories can exist in two primary forms: open access, which are open to the public, or closed access, restricted to specific users or groups, and they may cater to discipline-specific or broader research datasets. Choosing which type of data repository to upload to depends on several factors. See the table below for details:</p> <p>Researchers can analyze and visualize all their studies in one convenient view on the SomaLogic <a href="https://somalogic.com/life-sciences-portal/">Life Sciences Portal</a>. Digital resources, such as <a href="https://somalogic.com/datadelve-statistics/">DataDelve™ Statistics</a> and the <a href="https://somalogic.com/somascan-menu/">SomaScan Menu</a>, are easily accessed from the portal, too.</p> <p>The SomaLogic Technical Support team is always available to support researchers and repository owners. <a href="/cdn-cgi/l/email-protection#0e7a6b6d667d7b7e7e617c7a4e7d61636f626169676d206d6163">Email us</a> with questions.</p> </div> </div> </div><div data-id="tab_3" class="tab-title " data-text="About the NIH requirement to upload data">About the NIH requirement to upload data</div><div class="tab " id="tab_3"><div class="icon align-center"> <p style="margin: 0px;"><img loading="lazy" decoding="async" class="aligncenter wp-image-5928" src="https://somalogic.com/wp-content/uploads/2023/10/NIH-2012-logo-300x188.png" alt="NIH (National Institutes of Health) Logo" width="200" height="125" srcset="https://somalogic.com/wp-content/uploads/2023/10/NIH-2012-logo-300x188.png 300w, https://somalogic.com/wp-content/uploads/2023/10/NIH-2012-logo.png 337w" sizes="auto, (max-width: 200px) 100vw, 200px" /></p> <div class="pl-40">In addition to research journals, the National Institutes of Health (NIH) has issued a <a href="https://sharing.nih.gov/data-management-and-sharing-policy" target="_blank" rel="noopener">Data Management and Sharing (DMS) policy</a> from 2023 onwards to promote the sharing of scientific data. Besides the multiple benefits to sharing scientific data, the idea is to ultimately facilitate the development of treatments and products that improve human health.</div> </div> </div><div data-id="tab_4" class="tab-title " data-text="How to upload SomaScan data to public repositories">How to upload SomaScan data to public repositories</div><div class="tab " id="tab_4"><div class="icon align-center"> <p style="margin: 0px;"><img loading="lazy" decoding="async" class="aligncenter wp-image-5929 size-medium" src="https://somalogic.com/wp-content/uploads/2023/10/loadingAnAdat_White-300x264.png" alt="Image of SomaLogic repository ReadMe file. This explains how to load our ADAT file" width="300" height="264" srcset="https://somalogic.com/wp-content/uploads/2023/10/loadingAnAdat_White-300x264.png 300w, https://somalogic.com/wp-content/uploads/2023/10/loadingAnAdat_White-284x250.png 284w, https://somalogic.com/wp-content/uploads/2023/10/loadingAnAdat_White.png 400w" sizes="auto, (max-width: 300px) 100vw, 300px" /></p> <div class="pl-40"> <p>SomaScan data are presented in an ADAT format, a SomaLogic-specific, tab-delimited text file that’s small enough to fit on a standard desktop computer. ADAT files can be read easily into any R/Python scripting languages using our ADAT reader function in <a href="https://github.com/SomaLogic/SomaDataIO" target="_blank" rel="noopener">SomaDataIO</a> (R package) or <a href="https://github.com/SomaLogic/Canopy" target="_blank" rel="noopener">Canopy</a> (Python package). For uploading to public data repositories, we recommend that SomaScan data owners provide ADAT files formatted as they received them from SomaLogic.</p> <p>For more information on ADAT format or handling SomaScan data, please <a href="/cdn-cgi/l/email-protection#473322242f343237372835330734282a262b28202e246924282a">email</a> the SomaLogic Technical Support team.</p> </div> </div> </div><div data-id="tab_5" class="tab-title " data-text="Assistance: SomaLogic Technical Support">Assistance: SomaLogic Technical Support</div><div class="tab " id="tab_5"><div class="icon align-center"> <p style="margin: 0px;"><img loading="lazy" decoding="async" class="aligncenter wp-image-4826" src="https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-284x300.png" alt="" width="170" height="179" srcset="https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-284x300.png 284w, https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-970x1024.png 970w, https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-768x810.png 768w, https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-1456x1536.png 1456w, https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-1941x2048.png 1941w, https://somalogic.com/wp-content/uploads/2023/07/Somalogic-Icon_K_RGB_110520-237x250.png 237w" sizes="auto, (max-width: 170px) 100vw, 170px" /></p> <div class="pl-40"> <p>The SomaLogic Technical Support team is available throughout the analysis process – from initial questions and sample prep, to bioinformatics analysis and questions and final delivery of data.<br /> Please <a href="/cdn-cgi/l/email-protection#394d5c5a514a4c4949564b4d794a56545855565e505a175a5654">email our team here</a>.</p> </div> </div> </div> </div> </div></div> </div> </div><div class="wrap grey wrap-low-bottom-padding" id="wrap_3" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-10 cell-offset-md-1 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><h2>Deepen your molecular insights with the SomaScan Platform</h2> <p>The <a href="https://somalogic.com/somascan-platform/">SomaScan Platform</a> is a single platform from discovery to development that gives researchers access to half the genetically encoded human proteome (11,000 protein measurements). The technology is powered by SOMAmer® (Slow Off-rate Modified Aptamer) Reagents, which provide researchers with reliability and reproducibility unparalleled in the proteomics industry.</p> <p><strong>Read more at the links below:</strong></p> </div> </div></div> </div> </div><div class="wrap grey full-width-ceros" id="wrap_4" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center mb-60"><div style="position:relative;width:auto;padding:0 0 27.34%;height:0;top:0;left:0;bottom:0;right:0;margin:0;border:0 none" id="experience-659f0c8ec9a28" data-aspectRatio="3.6571" data-mobile-aspectRatio="1.3500"><iframe title="Full Width Cards Carousel" allowfullscreen src="https://view.ceros.com/somalogic/full-width-cards-carousel" style="position:absolute;top:0;left:0;bottom:0;right:0;margin:0;padding:0;border:0 none;height:1px;width:1px;min-height:100%;min-width:100%" frameborder="0" class="ceros-experience" scrolling="no"></iframe></div><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="text/javascript" src="https://view.ceros.com/scroll-proxy.min.js" data-ceros-origin-domains="view.ceros.com"></script></div> </div></div> </div> </div><div class="wrap white " id="wrap_5" title=""> <div class="container"> <div class="grid"><div class="text-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0" > <div class="a-center"><h2>Additional resources to learn more</h2> </div> </div><div class="resources-block cell-md-12 cell-offset-md-0 cell-sm-12 cell-offset-sm-0"> <div class="owl-carousel cards two-columns" data-items="3"><div class="card owl-block white-bg resource-card" style="background-image: url(https://somalogic.com/wp-content/uploads/2022/07/iStock-1214057464-scaled-2.jpg);" title="Graphic of different size circles with lines connecting them"> <div> <div class="content"> <h3><span>White paper</span>The missing link between genes and disease: Discovery of protein quantitative trait loci using high-plex protein profiling</h3> The ability to sequence the human genome has enabled researchers to identify genetic variants associated with disease risk, but identifying causal genes or mechanisms has proven to be much more difficult. Genes provide the blueprints to make proteins, which are essential functional molecules of the human body. Mutations of proteins and disruption of protein networks can cause diseases, which is why proteins are the target molecules for over 90% of approved therapeutics. </div> <p class="a-center"><a href="https://somalogic.com/white-paper/pqtl-white-paper/" class="btn blue-border">Learn more</a></p> </div> </div><div class="card owl-block white-bg resource-card" style="background-image: url(https://somalogic.com/wp-content/uploads/2023/07/CV_whitePaper_Preview.jpg);" title="Image of many samples in a lab with microscope"> <div> <div class="content"> <h3><span>White paper</span>Ensuring reproducibility in proteomics: Why coefficient of variation is a critical metric </h3> The SomaScan® Assay from SomaLogic is the only proteomic technology capable of measuring thousands of proteins while achieving a high throughput with high reproducibility. The platform is powered by chemically modified DNA aptamers called SOMAmer® reagents. SOMAmer reagents consist of short single-stranded DNA sequences that incorporate hydrophobic modifications, greatly expanding the physiochemical diversity of the large randomized nucleic acid libraries from which the SOMAmer reagents are selected. The performance metrics for all SOMAmer reagents in human serum and plasma are provided via the SomaScan Assay online menu tool at menu.somalogic.com. Although SomaLogic’s core features (high specificity, sensitivity, and reproducibility) are the main reasons the SomaScan Platform is utilized from biomarker discovery to clinical diagnosis, the power of its low coefficients of variation (CVs) is underappreciated. The SomaScan Assay has maintained a median CV of ~5%, which results in the ability to detect smaller biological changes with higher study power compared to other proteomic technologies. The following discussion captures the vast benefits of low CVs, as well as the specific value of the unrivaled SomaScan Platform CVs. </div> <p class="a-center"><a href="https://somalogic.com/white-paper/ensuring-reproducibility-in-proteomics-why-coefficient-of-variation-is-a-critical-metric/" class="btn blue-border">Learn more</a></p> </div> </div></div> </div></div> </div> </div></main> <footer> <div class="footer-top"> <div class="container"> <div class="grid"> <div class="cell-md-6"> <img src="https://somalogic.com/wp-content/themes/soma/img/SomaLogic-SBI-Dual-Logo-White.svg" alt="Somalogic logo" class="footer-logo" /> <p>SomaLogic Operating Co., Inc.<br /> 2945 Wilderness Pl. 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