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Filters are best used by combining two or more to narrow down the results.</p> <div class="search-box d-flex"> <label for="edit-keywords" class="sr-only">Keywords</label> <input class="search-box__input flex-grow-1 clear-search-box" id="edit-keywords" type="search" placeholder="Keywords" name="keywords" value="" maxlength="128" /> <button type="submit" class="search-box__button button button--icon icon--search icon--text-hidden " value="Search resources">Search resources</button> </div> <button class="listing-filter__toggle" type="button" data-bs-toggle="collapse" aria-expanded="true" data-bs-target="#listing-filter__target" aria-controls="listing-filter__target"> <span class="listing-filter__toggle-title">Filters</span> </button> </div> </header> <div id="listing-filter__target" class="listing-filter__target collapse show"> <div class="container"> <div class="row mb-4"> <div class="col-12"> <div class="row row-cols-1 row-cols-md-2 row-cols-xl-4"> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-audience">Audience</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="audience[]" id="edit-audience"> <option value="508" >Researcher</option> <option value="509" >Technician / Vet</option> <option value="582" >Ethical Review Body</option> <option value="506" selected>Research Organisation / Funder / Journal</option> <option value="507" >Regulator: Animal procedures</option> <option value="581" >Regulator: Safety assessment</option> </select> </div> </div> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-resource-type">Resource type</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="resource_type[]" id="edit-resource-type"> <option value="491" >E-learning</option> <option value="493" >Guidance</option> <option value="494" >Hard copy</option> <option value="938" >Network</option> <option value="937" >Newsletter</option> <option value="532" >Overview</option> <option value="495" >Tool</option> <option value="496" >Webinar and video</option> </select> </div> </div> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-topic">Resource topic</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="topic[]" id="edit-topic"> <option value="504" >Alternatives</option> <option value="497" >Experimental design and reporting</option> <option value="510" >Genetic modification</option> <option value="501" >Handling</option> <option value="502" >Husbandry</option> <option value="511" >In vivo techniques</option> <option value="512" >New approach methodologies</option> <option value="513" >Research culture and ethical review</option> <option value="498" >Toxicology and regulatory sciences</option> <option value="505" >Welfare assessment</option> </select> </div> </div> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-model">Model</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="model[]" id="edit-model"> <option value="514" >Ex vivo</option> <option value="515" >In silico</option> <option value="516" >In vitro</option> <option class="option--sub-level" value="518" >-Simple in vitro model</option> <option class="option--sub-level" value="517" >-Complex in vitro model</option> <option value="519" >In vivo</option> <option class="option--sub-level" value="520" >-Mouse</option> <option class="option--sub-level" value="521" >-Rat</option> <option class="option--sub-level" value="522" >-Other rodent</option> <option class="option--sub-level" value="533" >-Rabbit</option> <option class="option--sub-level" value="523" >-Cat</option> <option class="option--sub-level" value="524" >-Dog</option> <option class="option--sub-level" value="525" >-Pig</option> <option class="option--sub-level" value="526" >-Ferret</option> <option class="option--sub-level" value="527" >-Non-human primate</option> <option class="option--sub-level" value="528" >-Other mammalian species</option> <option class="option--sub-level" value="529" >-Zebrafish</option> <option class="option--sub-level" value="530" >-Amphibian</option> <option class="option--sub-level" value="531" >-Invertebrate</option> </select> </div> </div> </div> </div> </div> <div data-drupal-selector="edit-actions" class="form-actions js-form-wrapper form-wrapper" id="edit-actions"><input data-drupal-selector="edit-submit-resources-v2" class="button--small button js-form-submit form-submit" type="submit" id="edit-submit-resources-v2" value="Update results" /> <input data-drupal-selector="edit-reset-resources-v2" type="submit" id="edit-reset-resources-v2" name="reset" value="Reset" class="button js-form-submit form-submit button--secondary button--small" /> </div> </div> </div> </div> </form> <div class="breakout s8080-component "> <div class="container"> <h2 class="results-count py-3"> <span class="results-count__number">24 results</span> </h2> <div class="s8080-component cards cards--25x4 cards--default"> <div class="row row-cols-1 row-cols-md-2 row-cols-lg-3 row-cols-xl-4"><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/amphibian-webinar" class="card__link " title="Amphibian care and welfare webinar"><span><span>Amphibian care and welfare webinar</span> </span></a> </div> <div class="card__body"> <p>A joint webinar from the NC3Rs/RSPCA Animals in Science department on refining the use of amphibians in research.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2024-10/frog_head.jpg?itok=xlt3dVsm" width="1000" height="562" alt="Rana temporaria" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/3rs-SAT" class="card__link " title="3Rs self-assessment tools"><span><span>3Rs self-assessment tools</span> </span></a> </div> <div class="card__body"> <p>Our self-assessment tools are currently under redevelopment. Find out more about this project and our future plans.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Self-assessment-tool-icon.png?itok=21UlXzTN" width="1000" height="562" alt="Icon of a checklist with "3Rs" enlarged by a magnifying glass" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/developing-and-implementing-institutional-3rs-strategy" class="card__link " title="Developing and implementing an institutional 3Rs strategy"><span><span>Developing and implementing an institutional 3Rs strategy</span> </span></a> </div> <div class="card__body"> <p>Guidance for those overseeing animal research at institutions on recognising 3Rs opportunities and putting them into practice.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Institutional%20strategy%20Twitter%20card_0.png?itok=3i8MOb1c" width="1000" height="562" alt="The front cover of the "Developing and implementing an institutional 3Rs strategy" document on a green background." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/new-approach-methodologies-hub" class="card__link " title="New approach methodologies hub"><span><span>New approach methodologies hub</span> </span></a> </div> <div class="card__body"> <p>Resources and activities around NAMs (replacement technologies used to assess drug and chemical safety).</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2023-06/Organ%20on%20a%20chip%20%28Shutterstock%29_0.jpg?itok=rthEUTIs" width="1000" height="562" alt="Organ on a chip system. The chip is being held against a blue background with orange tweezers causing the channels on the chip to have an orange hue." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/nams-network" class="card__link " title="NAMs Network"><span><span>NAMs Network</span> </span></a> </div> <div class="card__body"> <p>Join our community of researchers, developers, industry and regulatory end-users working together to accelerate the use of new approach methodologies.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Network </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2024-02/NAMs%20network%20graphic.png?h=02faacd5&itok=j9xlBUD-" width="1000" height="562" alt="Graphic showing some of the range of applications of NAMs" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/nams-resources" class="card__link " title="NAMs resources"><span><span>NAMs resources</span> </span></a> </div> <div class="card__body"> <p>Learn more about what NAMs are and how they can be applied to progress the 3Rs.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2023-10/AdobeStock_551825007.jpeg?itok=oo8DVMff" width="1000" height="562" alt="Decorative image" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-champion" class="card__link " title="The 3Rs Champion"><span><span>The 3Rs Champion</span> </span></a> </div> <div class="card__body"> <p>Guidance on the role of the 3Rs Champion within the research community.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2024-01/3Rs%20Champion.png?itok=7hk-hTtL" width="1000" height="562" alt="A white trophy with the term '3Rs' on it sits on a bright yellow background. " /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/checklists-use-animals-overseas" class="card__link " title="Checklists for the use of animals overseas"><span><span>Checklists for the use of animals overseas </span> </span></a> </div> <div class="card__body"> <p>Checklists to assist funders in assessing whether animal research conducted overseas conforms to UK welfare standards.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2023-08/World%20map%20ultramarine.jpg?h=f2387343&itok=Bk4B4apx" width="1000" height="562" alt="World Map" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/peer-review-and-advice-service" class="card__link " title="Peer review and advice service"><span><span>Peer review and advice service</span> </span></a> </div> <div class="card__body"> <p>How funding bodies can embed the 3Rs in their peer review process, including details of our review and advice service.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Peer%20review%20icon%20%28purple%29.png?itok=ggz2rXMo" width="1000" height="562" alt="Icon representing peer review: two people connected by arrows going round a paper" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/automated-monitoring-animal-behaviour" class="card__link " title="Automated monitoring of animal behaviour"><span><span>Automated monitoring of animal behaviour </span> </span></a> </div> <div class="card__body"> <p>Information and guidance for the use of automated systems to monitoring the behaviour of animals in preclinical research.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2023-01/RBB.png?itok=G50l6Jdh" width="1000" height="562" alt="Image of mouse being observed (decorative)" /> </div> </article> </div><div class="col mt-4"> <article class="card card--highlight"> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/grimace-scales" class="card__link " title="Grimace scales"><span><span>Grimace scales</span> </span></a> </div> <div class="card__body"> <p>Posters and other resources on the use of grimace scales to assess pain in laboratory animals.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Overview | Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-08/Mouse%2C%20rat%20and%20rabbit%20grimace%20scale%20posters.png?itok=UNr1Kpxo" width="1000" height="562" alt="The mouse, rat and rabbit grimace scale posters layered over each other." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/breeding-and-colony-management/sharing-and-archiving-ga-mice" class="card__link " title="Sharing and archiving of GA mice"><span><span>Sharing and archiving of GA mice</span> </span></a> </div> <div class="card__body"> <p>Guidance document on opportunities to reduce and refine the use of GA mice through cryopreservation and sharing.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Sharing%20archiving%20Twitter%20card.png?itok=MtNcqWwa" width="1000" height="562" alt="The front cover of the "Sharing & archiving of genetically altered mice" document on a green background." /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://arriveguidelines.org" class="card__link " title="The ARRIVE guidelines"><span><span>The ARRIVE guidelines</span> </span></a> </div> <div class="card__body"> <p>Reporting guidelines for animal experiments, and additional resources to support their use.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance | Hard copy | Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/NC3Rs%20ARRIVE-guidelines-Z-card.jpg?itok=1Ymu9kxw" width="1000" height="562" alt="a physical copy of the ARRIVE guidelines" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://vimeo.com/581109980/0f5f189564" class="card__link " title="3Rs self-assessment tools for research groups and institutions"><span><span>3Rs self-assessment tools for research groups and institutions </span> </span></a> </div> <div class="card__body"> <p>A webinar introducing our two 3Rs self-assessment tools; one for research groups and the other for research institutions.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/3Rs%20self-assessment%20tools%20for%20research%20groups%20and%20institutions%20.jpg?h=c79cac51&itok=uwkltu3A" width="1000" height="562" alt="Webinar title slide: 3Rs self-assessment tools" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/nc3rs-and-3rs-during-covid-19" class="card__link " title="The NC3Rs and the 3Rs during COVID-19"><span><span>The NC3Rs and the 3Rs during COVID-19</span> </span></a> </div> <div class="card__body"> <p>Practical resources to ensure that the 3Rs are considered and kept a priority when services are disrupted.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/covid%2019.png?itok=fiwLICT4" width="1000" height="562" alt="Illustration of a COVID-19 particle" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/culture-care" class="card__link " title="Culture of care"><span><span>Culture of care</span> </span></a> </div> <div class="card__body"> <p>Promoting an institution-wide commitment to animal welfare.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-10/Black%20mouse%20sitting%20on%20gloved%20hands.jpg?itok=IS6JBJ2J" width="1000" height="562" alt="Black mouse sitting on open hands. The technician is wearing a blue coveralls and blue medical grade gloves." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/open-research-and-communication" class="card__link " title="Open research and communication"><span><span>Open research and communication</span> </span></a> </div> <div class="card__body"> <p>Our approach to ensuring transparency in our work and its outputs.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Researcher%20presenting%20work%20%28open%20science%20and%20communication%29.jpg?h=6d9cebce&itok=Mltji_ka" width="1000" height="562" alt="A researcher presents his work at a conference" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/research-culture-and-3rs" class="card__link " title="Research culture and the 3Rs"><span><span>Research culture and the 3Rs</span> </span></a> </div> <div class="card__body"> <p>Promoting values and behaviours that support an institution-wide commitment to the 3Rs.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Scientists%20talking%20in%20lab%20%28research%20culture%29.jpg?h=582151e0&itok=ta1eRAwh" width="1000" height="562" alt="Researchers having a conversation in the lab" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://www.youtube.com/watch?v=CIP0Tz7MEPc" class="card__link " title="The ARRIVE guidelines 2.0"><span><span>The ARRIVE guidelines 2.0</span> </span></a> </div> <div class="card__body"> <p>A webinar introducing the revised ARRIVE guidelines, the items in the ARRIVE Essential 10, and relevant resources.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Webinar%20Front%20Slide%20-%20ARRIVE%20NPdS.png?itok=Bnt00TJe" width="1000" height="562" alt="The front slide of a webinar presentation by the NC3Rs' Nathalie Percie du Sert" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/mouse-handling/mouse-handling-posters" class="card__link " title="Mouse handling: Posters"><span><span>Mouse handling: Posters</span> </span></a> </div> <div class="card__body"> <p>To support the adoption of non-aversive methods for picking up mice, we have produced an A2-sized poster for display.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Hard copy </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-10/Mouse%20handling%20poster%20screenshot.png?itok=HzlQDVgv" width="1000" height="562" alt="Screenshot of the NC3Rs Mouse Handling poster which outlines guidance on non-aversive handling techniques for the laboratory mouse" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/responsibility-use-animals-bioscience-research" class="card__link " title="Responsibility in the use of animals in bioscience research"><span><span>Responsibility in the use of animals in bioscience research</span> </span></a> </div> <div class="card__body"> <p>Expectations of the major UK research council and charitable funding bodies for those working with vertebrates in biosciences research.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Responsibility%20in%20biosciences%20guidelines%20Twitter%20card.png?itok=eZOsdgTd" width="1000" height="562" alt="The front cover of the "Responsibility in the use of animals in bioscience research" document on a green background." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/workshop-improving-peer-review-vivo-research-proposals" class="card__link " title="Workshop: Improving peer review of in vivo research proposals"><span><span>Workshop: Improving peer review of in vivo research proposals</span> </span></a> </div> <div class="card__body"> <p>Videos from our May 2018 workshop on experimental design for panel members of the NC3Rs, BBSRC, CRUK, MRC and Wellcome Trust.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/Peer-review.png?itok=3XlP73Mb" width="1000" height="562" alt="a cartoon of a piece of paper, with two human outlines at the top right and bottom left" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/non-human-primate-accommodation-care-and-use-guidelines" class="card__link " title="Non-human primate accommodation, care and use guidelines"><span><span>Non-human primate accommodation, care and use guidelines</span> </span></a> </div> <div class="card__body"> <p>Guidelines on non-human primate accommodation, care and use adopted by the major UK bioscience funders.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance | Hard copy </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/NHP%20guidelines%20Twitter%20card.png?itok=pZ15z8H4" width="1000" height="562" alt="The front cover of the "Non-human primate accommodation, care and use guidelines" document on a green background." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/institutional-framework-3rs" class="card__link " title="Institutional framework for the 3Rs"><span><span>Institutional framework for the 3Rs</span> </span></a> </div> <div class="card__body"> <p>Seven related principles that all research institutions should adopt or consider.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> </span> </div> </div> <div class="card__image"> <img loading="lazy" 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