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class="page-title">Category: <span>Neurology & Neurosurgery</span></h1><div class="taxonomy-description"><p>Specialty: Neurology & Neurosurgery</p> </div> </header> <article id="post-7923" class="post-7923 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/" rel="bookmark">Crossing Barriers in CNS Repair: Dr. Fengfeng Bei on Neural Regeneration and Gene Therapy</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/10/virus-infected-brain-on-.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" fetchpriority="high" /> </div> </header>  <div class="entry-summary"> <p>About one-third of epilepsy patients have a disease that is considered drug-resistant, meaning they have failed at least two medications. For these individuals, neurosurgical procedures offer the best chance of bringing their disease under control. Remarkably, the average time it takes for someone with…</p> <a href="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7923" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7923" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7923" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Crossing%20Barriers%20in%20CNS%20Repair%3A%20Dr.%20Fengfeng%20Bei%20on%20Neural%20Regeneration%20and%20Gene%20Therapy&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F10%2F30%2Fcrossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="1c6d18d4de" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/10/30/crossing-barriers-in-cns-repair-dr-fengfeng-bei-on-neural-regeneration-and-gene-therapy/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7921" class="post-7921 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/" rel="bookmark">Improving Outcomes for Patients With Drug-resistant Epilepsy Through Surgery</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/10/illustration-of-human-no.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" /> </div> </header>  <div class="entry-summary"> <p>Although current surgical approaches for treating drug-resistant epilepsy are already good, researchers at the Brigham are focused on developing treatments that are even more effective and less invasive. John David Rolston, MD, PhD, director of Epilepsy Surgery, highlights some of these promising efforts.</p> <a href="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7921" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7921" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7921" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Improving%20Outcomes%20for%20Patients%20With%20Drug-resistant%20Epilepsy%20Through%20Surgery&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F10%2F22%2Fimproving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="c06f1bd914" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/10/22/improving-outcomes-for-patients-with-drug-resistant-epilepsy-through-surgery/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7846" class="post-7846 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/" rel="bookmark">Patient-reported Autonomic Symptoms Do Not Correlate With Objective Dysfunction</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/06/female-having-heart-asth-hero.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" /> </div> </header>  <div class="entry-summary"> <p>Brigham and Women’s Hospital researchers have confirmed in a large cohort what previous research suggested: a lack of correlation between subjective dysautonomia and standardized objective testing.</p> <a href="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7846" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7846" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7846" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Patient-reported%20Autonomic%20Symptoms%20Do%20Not%20Correlate%20With%20Objective%20Dysfunction&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F06%2F17%2Fpatient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="7d89c71f2b" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/06/17/patient-reported-autonomic-symptoms-do-not-correlate-with-objective-dysfunction/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7845" class="post-7845 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/" rel="bookmark">Deep Brain Stimulation Used to Map Therapeutic Targets for Four Brain Disorders</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/06/the-medical-notion-of-de.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Using deep brain stimulation (DBS) as a research tool, Brigham and Women’s Hospital scientists have identified distinct neural circuits for Parkinson’s disease, dystonia, obsessive-compulsive disorder (OCD), and Tourette’s syndrome.</p> <a href="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7845" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7845" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7845" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Deep%20Brain%20Stimulation%20Used%20to%20Map%20Therapeutic%20Targets%20for%20Four%20Brain%20Disorders&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F06%2F11%2Fdeep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="e0e54c78b5" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/06/11/deep-brain-stimulation-used-to-map-therapeutic-targets-for-four-brain-disorders/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7826" class="post-7826 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/" rel="bookmark">A Cellular Model Linking Impaired Neuronal Protein Turnover to Person-Specific Alzheimer’s Disease Risk</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/06/brain-and-dna-as-genes-l-1.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Researchers at Brigham and Women’s Hospital are using neurons derived from induced pluripotent stem cells (iNs) as a highly controlled, reproducible model system for understanding cellular pathways that mediate neuropathogenesis directly downstream of genetic risk factors.</p> <a href="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7826" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7826" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7826" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20A%20Cellular%20Model%20Linking%20Impaired%20Neuronal%20Protein%20Turnover%20to%20Person-Specific%20Alzheimer%27s%20Disease%20Risk&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F05%2F29%2Fa-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="4e8d2e43c6" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/05/29/a-cellular-model-linking-impaired-neuronal-protein-turnover-to-person-specific-alzheimers-disease-risk/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7819" class="post-7819 post type-post status-publish format-standard has-post-thumbnail hentry category-cancer category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/" rel="bookmark">Exploring How to Enhance Drug Delivery and Efficacy Through Nanoparticles and Macroscale Materials</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/05/gene-and-cell-therapy-drug-delivery-nanoparticles-1.png" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="Micrograph of a hydrogel, nanoparticle for gene delivery, and microneedle patch" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Natalie Artzi, PhD, a principal investigator in the Brigham and Women’s Hospital Department of Medicine, has changed our basic understanding of biomaterials under different environmental and pathological states. Her lab is dedicated to designing smart biomaterial platforms and medical devices to improve human health.</p> <a href="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7819" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7819" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7819" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Exploring%20How%20to%20Enhance%20Drug%20Delivery%20and%20Efficacy%20Through%20Nanoparticles%20and%20Macroscale%20Materials&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F05%2F20%2Fexploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="12d865de6a" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/05/20/exploring-how-to-enhance-drug-delivery-and-efficacy-through-nanoparticles-and-macroscale-materials/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7679" class="post-7679 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/" rel="bookmark">Proof of Concept: Presenilin-based Gene Therapy Targets Early-onset Alzheimer’s Disease Carrying PSEN Mutations</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/03/brain-and-dna-as-genes-l-2.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Mutations in human presenilin genes (PSEN1 and PSEN2) are the major cause of early-onset familial Alzheimer’s disease (FAD). Building on the previous work, Brigham reserachers have published preclinical evidence that using gene therapy to deliver a functional copy of PSEN1 may someday be able to treat FAD.</p> <a href="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7679" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7679" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7679" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Proof%20of%20Concept%3A%20Presenilin-based%20Gene%20Therapy%20Targets%20Early-onset%20Alzheimer%27s%20Disease%20Carrying%20PSEN%20Mutations&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F03%2F26%2Fproof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="fbc669e75b" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/03/26/proof-of-concept-presenilin-based-gene-therapy-targets-early-onset-alzheimer-s-disease-carrying-psen-mutations/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7616" class="post-7616 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/" rel="bookmark">AAN 2024: Brigham Neurologists Share Latest Research</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/03/conceptual-illustration-1-2.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>The American Academy of Neurology (AAN) will hosts its 2024 annual meeting on April 13 – 18 in Denver, CO and virtually. Faculty from the Department of Neurology at Brigham and Women’s Hospital will join thousands of international colleagues in presenting their latest research at AAN 2024.</p> <a href="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7616" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7616" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7616" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20AAN%202024%3A%20Brigham%20Neurologists%20Share%20Latest%20Research&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F03%2F22%2Faan-2024-brigham-neurologists-share-latest-research%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="e77c3ce970" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/03/22/aan-2024-brigham-neurologists-share-latest-research/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7575" class="post-7575 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/" rel="bookmark">Case Report: Recurrent Intraventricular Hemorrhage in Cerebral Proliferative Angiopathy With Very Long-term Follow-up</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/02/close-up-view-of-a-docto.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Cerebral proliferative angiopathy (CPA) is a cerebral vascular malformation with distinctive features. Brigham and Women’s Hospital researchers present one of the few reports of long-term follow-up of a patient with hemorrhage in CPA: 32 years of data on a patient who had recurrent hemorrhage.</p> <a href="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/" class="more-link">Read More...</a><div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon sd-sharing"><h3 class="sd-title">Share this:</h3><div class="sd-content"><ul><li class="share-linkedin"><a rel="nofollow noopener noreferrer" data-shared="sharing-linkedin-7575" class="share-linkedin sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/?share=linkedin" target="_blank" title="Click to share on LinkedIn" ><span></span><span class="sharing-screen-reader-text">Click to share on LinkedIn (Opens in new window)</span></a></li><li class="share-twitter"><a rel="nofollow noopener noreferrer" data-shared="sharing-twitter-7575" class="share-twitter sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/?share=twitter" target="_blank" title="Click to share on Twitter" ><span></span><span class="sharing-screen-reader-text">Click to share on Twitter (Opens in new window)</span></a></li><li class="share-facebook"><a rel="nofollow noopener noreferrer" data-shared="sharing-facebook-7575" class="share-facebook sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/?share=facebook" target="_blank" title="Click to share on Facebook" ><span></span><span class="sharing-screen-reader-text">Click to share on Facebook (Opens in new window)</span></a></li><li class="share-print"><a rel="nofollow noopener noreferrer" data-shared="" class="share-print sd-button share-icon no-text" href="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/" target="_blank" title="Click to print" ><span></span><span class="sharing-screen-reader-text">Click to print (Opens in new window)</span></a></li><li class="share-email"><a rel="nofollow noopener noreferrer" data-shared="" class="share-email sd-button share-icon no-text" href="mailto:?subject=%5BShared%20Post%5D%20Case%20Report%3A%20Recurrent%20Intraventricular%20Hemorrhage%20in%20Cerebral%20Proliferative%20Angiopathy%20With%20Very%20Long-term%20Follow-up&body=https%3A%2F%2Fwww.brighamhealthonamission.org%2F2024%2F02%2F29%2Fcase-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up%2F&share=email" target="_blank" title="Click to email a link to a friend" data-email-share-error-title="Do you have email set up?" data-email-share-error-text="If you're having problems sharing via email, you might not have email set up for your browser. You may need to create a new email yourself." data-email-share-nonce="5feb6eb96e" data-email-share-track-url="https://www.brighamhealthonamission.org/2024/02/29/case-report-recurrent-intraventricular-hemorrhage-in-cerebral-proliferative-angiopathy-with-very-long-term-follow-up/?share=email"><span></span><span class="sharing-screen-reader-text">Click to email a link to a friend (Opens in new window)</span></a></li><li class="share-end"></li></ul></div></div></div> </div> </article> <article id="post-7568" class="post-7568 post type-post status-publish format-standard has-post-thumbnail hentry category-neurology-neurosurgery"> <header class="entry-header"> <h1 class="entry-title textcenter-xs"><a href="https://www.brighamhealthonamission.org/2024/02/27/artificial-intelligence-machine-learning-and-the-future-of-neurosurgical-care/" rel="bookmark">Artificial Intelligence, Machine Learning, and the Future of Neurosurgical Care</a></h1> <div class="entry-thumbnail"> <img width="300" height="225" src="https://www.brighamhealthonamission.org/wp-content/uploads/2024/02/3d-rendering-of-human-br.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" decoding="async" loading="lazy" /> </div> </header>  <div class="entry-summary"> <p>Timothy Smith, MD, PhD, MPH, a neurosurgeon-scientist in the Brigham’s Department of Neurosurgery, is exploring how to utilize artificial intelligence and machine learning to optimize neurosurgical patient care. 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