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Filters are best used by combining two or more to narrow down the results.</p> <div class="search-box d-flex"> <label for="edit-keywords" class="sr-only">Keywords</label> <input class="search-box__input flex-grow-1 clear-search-box" id="edit-keywords" type="search" placeholder="Keywords" name="keywords" value="" maxlength="128" /> <button type="submit" class="search-box__button button button--icon icon--search icon--text-hidden " value="Search resources">Search resources</button> </div> <button class="listing-filter__toggle" type="button" data-bs-toggle="collapse" aria-expanded="true" data-bs-target="#listing-filter__target" aria-controls="listing-filter__target"> <span class="listing-filter__toggle-title">Filters</span> </button> </div> </header> <div id="listing-filter__target" class="listing-filter__target collapse show"> <div class="container"> <div class="row mb-4"> <div class="col-12"> <div class="row row-cols-1 row-cols-md-2 row-cols-xl-4"> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-audience">Audience</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="audience[]" id="edit-audience"> <option value="508" >Researcher</option> <option value="509" >Technician / Vet</option> <option value="582" >Ethical Review Body</option> <option value="506" >Research Organisation / Funder / Journal</option> <option value="507" >Regulator: Animal procedures</option> <option value="581" >Regulator: Safety assessment</option> </select> </div> </div> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-resource-type">Resource type</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="resource_type[]" id="edit-resource-type"> <option value="491" >E-learning</option> <option value="493" >Guidance</option> <option value="494" >Hard copy</option> <option value="938" >Network</option> <option value="937" >Newsletter</option> <option value="532" >Overview</option> <option value="495" >Tool</option> <option value="496" >Webinar and video</option> </select> </div> </div> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-topic">Resource topic</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="topic[]" id="edit-topic"> <option value="504" >Alternatives</option> <option value="497" selected>Experimental design and reporting</option> <option value="510" >Genetic modification</option> <option value="501" >Handling</option> <option value="502" >Husbandry</option> <option value="511" >In vivo techniques</option> <option value="512" >New approach methodologies</option> <option value="513" >Research culture and ethical review</option> <option value="498" >Toxicology and regulatory sciences</option> <option value="505" >Welfare assessment</option> </select> </div> </div> <div class="col mt-4"> <div class="multi-select"> <label class="multi-select__label" for="edit-model">Model</label> <select class="multi-select__select selectpicker" data-size="12" data-selected-text-format="count" data-count-selected-text="{0} selected" title="- All -" multiple name="model[]" id="edit-model"> <option value="514" >Ex vivo</option> <option value="515" >In silico</option> <option value="516" >In vitro</option> <option class="option--sub-level" value="518" >-Simple in vitro model</option> <option class="option--sub-level" value="517" >-Complex in vitro model</option> <option value="519" >In vivo</option> <option class="option--sub-level" value="520" >-Mouse</option> <option class="option--sub-level" value="521" >-Rat</option> <option class="option--sub-level" value="522" >-Other rodent</option> <option class="option--sub-level" value="533" >-Rabbit</option> <option class="option--sub-level" value="523" >-Cat</option> <option class="option--sub-level" value="524" >-Dog</option> <option class="option--sub-level" value="525" >-Pig</option> <option class="option--sub-level" value="526" >-Ferret</option> <option class="option--sub-level" value="527" >-Non-human primate</option> <option class="option--sub-level" value="528" >-Other mammalian species</option> <option class="option--sub-level" value="529" >-Zebrafish</option> <option class="option--sub-level" value="530" >-Amphibian</option> <option class="option--sub-level" value="531" >-Invertebrate</option> </select> </div> </div> </div> </div> </div> <div data-drupal-selector="edit-actions" class="form-actions js-form-wrapper form-wrapper" id="edit-actions"><input data-drupal-selector="edit-submit-resources-v2" class="button--small button js-form-submit form-submit" type="submit" id="edit-submit-resources-v2" value="Update results" /> <input data-drupal-selector="edit-reset-resources-v2" type="submit" id="edit-reset-resources-v2" name="reset" value="Reset" class="button js-form-submit form-submit button--secondary button--small" /> </div> </div> </div> </div> </form> <div class="breakout s8080-component "> <div class="container"> <h2 class="results-count py-3"> <span class="results-count__number">20 results</span> </h2> <div class="s8080-component cards cards--25x4 cards--default"> <div class="row row-cols-1 row-cols-md-2 row-cols-lg-3 row-cols-xl-4"><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/arrive-manuscript-review-exercises" class="card__link " title="ARRIVE manuscript review exercises"><span><span>ARRIVE manuscript review exercises</span> </span></a> </div> <div class="card__body"> <p>Exercises to enhance critical analysis skills and improve your ability to evaluate scientific literature.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> E-learning </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2024-08/Screengrab%20of%20Microlearning%201_0.png?itok=QlPk7sY8" width="1000" height="562" alt="Screengrab of eLearning" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/conducting-pilot-study" class="card__link " title="Conducting a pilot study"><span><span>Conducting a pilot study</span> </span></a> </div> <div class="card__body"> <p>Reasons for conducting a pilot study and what you can do with the results.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Mouse%20with%20dice.jpg?h=dd03de20&itok=QA9s3C1s" width="1000" height="562" alt="A mouse in a continual trials apparatus, standing on some plastic dice" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/using-maskingblinding-vivo-experiments" class="card__link " title="Using masking/blinding in in vivo experiments"><span><span>Using masking/blinding in in vivo experiments</span> </span></a> </div> <div class="card__body"> <p>Practical guidance and examples of strategies that can be used to mask group allocation in animal studies.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-11/person%20with%20cupped%20hands_maskon_crimson150dpi-01.png?itok=SD1KyIBh" width="1000" height="562" alt="Two persons with one wearing a mask over their eyes" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/mrc-nc3rs-webinar-using-both-sexes-animal-experiments" class="card__link " title="MRC/NC3Rs webinar: Using both sexes in animal experiments"><span><span>MRC/NC3Rs webinar: Using both sexes in animal experiments</span> </span></a> </div> <div class="card__body"> <p>A webinar explaining the importance of using both sexes in animal experiments and things to consider when planning studies.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-08/Using%20both%20sexes%20webinar%20-%20welcome%20slide.jpg?itok=MQ0nociT" width="1000" height="562" alt="Welcome slide for the joint webinar with MRC in using both sexes in animal experiments. Shows pictures of the three speakers: Drs Stella Child, Natasha Karp and Sara Wells." /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resource-library/virtual-demonstrations-experimental-design-assistant" class="card__link " title="Virtual demonstrations of the Experimental Design Assistant"><span><span>Virtual demonstrations of the Experimental Design Assistant</span> </span></a> </div> <div class="card__body"> <p>Learn how our online EDA tool can help you plan rigorous experiments.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-10/EDA%20diagram%20two%20group%20comparison%20edited%20version.png?itok=tg8-1oUt" width="1000" height="562" alt="EDA diagram of an experiment representing a simple two-group comparison" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/introduction-systematic-reviews" class="card__link " title="Introduction to systematic reviews"><span><span>Introduction to systematic reviews</span> </span></a> </div> <div class="card__body"> <p>An introduction to systematic reviews, a powerful method used to assess accumulating evidence related to a specific research question.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance | Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-10/Stack%20of%20papers.jpg?itok=eYtQswr-" width="1000" height="562" alt="A stack of papers" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://arriveguidelines.org" class="card__link " title="The ARRIVE guidelines"><span><span>The ARRIVE guidelines</span> </span></a> </div> <div class="card__body"> <p>Reporting guidelines for animal experiments, and additional resources to support their use.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance | Hard copy | Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/NC3Rs%20ARRIVE-guidelines-Z-card.jpg?itok=1Ymu9kxw" width="1000" height="562" alt="a physical copy of the ARRIVE guidelines" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://eda.nc3rs.org.uk" class="card__link " title="The Experimental Design Assistant (EDA)"><span><span>The Experimental Design Assistant (EDA)</span> </span></a> </div> <div class="card__body"> <p>An online tool to guide researchers through designing experiments involving the use of animals.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance | Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2023-09/EDA-logo-white-with-text_BrominePurpleLargeBckgrnd.png?itok=xxxcrcrl" width="1000" height="562" alt="A crimson square with the EDA logo on it and the words 'Experimental Design Assistant'" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/tackling-experimental-design-your-funding-proposal" class="card__link " title="Tackling experimental design in your funding proposal"><span><span>Tackling experimental design in your funding proposal</span> </span></a> </div> <div class="card__body"> <p>Tips to avoid common pitfalls when describing your experimental design and methodology in a funding proposal.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/Experimental%20design%20tips%20blog%20post%20290x165.png?itok=gqJ2b1Z-" width="1000" height="562" alt="Three scientists sitting at a table discussing an open document" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://syrf.org.uk" class="card__link " title="The CAMARADES/ NC3Rs Systematic Review Facility (SyRF)"><span><span>The CAMARADES/ NC3Rs Systematic Review Facility (SyRF)</span> </span></a> </div> <div class="card__body"> <p>An online resource to help you perform systematic reviews and meta-analyses.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Tool </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/SyRF%20Logo%20v2-01.png?itok=VmCEo5gf" width="1000" height="562" alt="The logo of the SyRF systematic review facility" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://www.youtube.com/watch?v=CIP0Tz7MEPc" class="card__link " title="The ARRIVE guidelines 2.0"><span><span>The ARRIVE guidelines 2.0</span> </span></a> </div> <div class="card__body"> <p>A webinar introducing the revised ARRIVE guidelines, the items in the ARRIVE Essential 10, and relevant resources.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Webinar%20Front%20Slide%20-%20ARRIVE%20NPdS.png?itok=Bnt00TJe" width="1000" height="562" alt="The front slide of a webinar presentation by the NC3Rs' Nathalie Percie du Sert" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://vimeo.com/442640803/09faa99012" class="card__link " title="Best practice in experimental design"><span><span>Best practice in experimental design</span> </span></a> </div> <div class="card__body"> <p>An introduction for early career and postdoctoral researchers, applicable to both in vivo and in vitro experiments.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Best%20Practice%20Experimental%20Design%20Title%20Slide_wide.png?itok=XgXj3Inu" width="1000" height="562" alt="Title slide of webinar with photos of Dr Natasha Karp and Dr Esther Pearl" /> </div> </article> </div><div class="col mt-4"> <article class="card card--external"> <div class="card__content"> <div class="card__sub-title"> External link </div> <div class="card__title"> <a href="https://vimeo.com/421550517/65395c0b20" class="card__link " title="Systematic reviews of animal studies"><span><span>Systematic reviews of animal studies</span> </span></a> </div> <div class="card__body"> <p>A webinar for in vivo researchers or students with limited or no experience of systematic reviews.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/Systematic%20reviews%20slide.png?itok=ZDg6Z76T" width="1000" height="562" alt="A powerpoint slide showing the title of this webinar, and the headshots of Dr. Emily Sena and Dr. Nathalie Percie du Sert" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/how-decide-your-sample-size-when-power-calculation-not-straightforward" class="card__link " title="How to decide your sample size when the power calculation is not straightforward"><span><span>How to decide your sample size when the power calculation is not straightforward</span> </span></a> </div> <div class="card__body"> <p>Dr Simon Bate, from Statistical Sciences, GSK, covers a few questions about statistics and the 3Rs that he regularly encounters.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/simon%20bate_0.png?itok=tqDphPn0" width="1000" height="562" alt="An image of statistician Simon Bate, of GSK" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/importance-good-experimental-design-and-consequences-getting-it-wrong" class="card__link " title="The importance of good experimental design and the consequences of getting it wrong"><span><span>The importance of good experimental design and the consequences of getting it wrong</span> </span></a> </div> <div class="card__body"> <p>A recorded talk highlighting where bias can be introduced into experiments and the implications for results.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Webinar%20Front%20Slide%20-%20MacLeod%20v2.png?itok=kT48ulFs" width="1000" height="562" alt="The front slide of a webinar presentation by Professor Malcolm MacLeod" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/statistical-power-and-perils-chance" class="card__link " title="Statistical power and the perils of chance"><span><span>Statistical power and the perils of chance</span> </span></a> </div> <div class="card__body"> <p>A recorded talk explaining the dangers of underpowered experiments and how good design can increase the chances of finding reliable results.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Webinar%20Front%20Slide%20-%20Button%20v3.png?itok=YT3JIe3G" width="1000" height="562" alt="The front slide of a webinar presentation by Dr. Kate Button" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/study-design-effect-sizes-and-statistical-analyses" class="card__link " title="Study design: effect sizes and statistical analyses"><span><span>Study design: effect sizes and statistical analyses</span> </span></a> </div> <div class="card__body"> <p>Discussing key considerations when determining the effect size for a study, including why this is important for sample size calculations.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Webinar%20Front%20Slide%20-%20Inskip%20v2.png?itok=BwofL0LQ" width="1000" height="562" alt="The front slide of a webinar presentation by Professor Hazel Inskip" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/improving-bench-bedside-translation" class="card__link " title="Improving bench-to-bedside translation"><span><span>Improving bench-to-bedside translation</span> </span></a> </div> <div class="card__body"> <p>A video overview of common practices in preclinical research, and specific actions that can be taken to improve its robustness.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2022-01/Webinar%20Front%20Slide%20-%20Dirnagl%20v2.png?itok=jlYOFgax" width="1000" height="562" alt="The front slide of a webinar presentation by Professor Ulrich Dirnagl" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/workshop-improving-peer-review-vivo-research-proposals" class="card__link " title="Workshop: Improving peer review of in vivo research proposals"><span><span>Workshop: Improving peer review of in vivo research proposals</span> </span></a> </div> <div class="card__body"> <p>Videos from our May 2018 workshop on experimental design for panel members of the NC3Rs, BBSRC, CRUK, MRC and Wellcome Trust.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Webinar and video </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/Peer-review.png?itok=3XlP73Mb" width="1000" height="562" alt="a cartoon of a piece of paper, with two human outlines at the top right and bottom left" /> </div> </article> </div><div class="col mt-4"> <article class="card "> <div class="card__content"> <div class="card__title"> <a href="/3rs-resources/key-elements-well-designed-experiment" class="card__link " title="Key elements of a well-designed experiment"><span><span>Key elements of a well-designed experiment</span> </span></a> </div> <div class="card__body"> <p>Things to consider when designing your animal experiments.</p> </div> <div class="card__metadata"> <span class="card__tag me-3"> Guidance </span> </div> </div> <div class="card__image"> <img loading="lazy" src="/sites/default/files/styles/image_16_9/public/2021-11/_DSC9836.jpg?itok=9vtw6ki5" width="1000" height="562" alt="a mouse taking a food pellet form a metal feeder" /> </div> </article> </div></div> </div> </div> </div> <div class="mt-4 mb-4"> </div> </div> </div> </div> <div id="block-sharebar"> <div class="row"> <div class="col-md-12"> <div class="share-bar js-share-bar"> <button class="button 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