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It is less preferred than metformin. Use is recommended together with diet and exercise. It is taken by mouth. Glimepiride takes up to three hours for maximum effect and lasts for about a day. Common side effects include headache, nausea, and dizziness. Serious side effects may include low blood sugar. Use during pregnancy and breastfeeding is not recommended. It works mainly by increasing the amount of insulin released from the pancreas. 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class="text-muted"> An Entity of Type: <a href="http://dbpedia.org/ontology/ChemicalSubstance">chemical substance</a>, from Named Graph: <a href="http://dbpedia.org">http://dbpedia.org</a>, within Data Space: <a href="http://dbpedia.org">dbpedia.org</a> </div> </div> </div> <div class="row pt-2"> <div class="col-xs-9 col-sm-10"> Glimepiride, is an anti-diabetic medication used to treat type 2 diabetes. It is less preferred than metformin. Use is recommended together with diet and exercise. It is taken by mouth. Glimepiride takes up to three hours for maximum effect and lasts for about a day. Common side effects include headache, nausea, and dizziness. Serious side effects may include low blood sugar. Use during pregnancy and breastfeeding is not recommended. It works mainly by increasing the amount of insulin released from the pancreas. It is classified as a second-generation sulfonylurea. </div> <div class="col-xs-3 col-sm-2"> <a href="#" class="thumbnail"> <img src="http://commons.wikimedia.org/wiki/Special:FilePath/Glimepiride.svg?width=300" alt="thumbnail" class="img-fluid" /> </a> </div> </div> </div> </section>   <section> <div class="container-xl"> <div class="row"> <div class="table-responsive"> <table class="table table-hover table-sm table-light"> <thead> <tr> <th class="col-xs-3 ">Property</th> <th class="col-xs-9 px-3">Value</th> </tr> </thead> <tbody> <tr class="odd"><td class="col-2"><a class="uri" href="http://dbpedia.org/ontology/abstract">dbo:abstract</a> </td><td class="col-10 text-break"><ul> <li style="display:none;">جليميبرايد (بالإنجليزية: Glimepiride)‏ ويعرف بالأسماء التجارية دولسيل (بالإنجليزية: Dolcyl)‏ هو دواء يستخذم لعلاج داء السكري، يؤخد عن طريق الفم. (ar)</li> <li style="display:none;">Η γλιμεπιρίδη (glimepiride, αρχική επωνυμία Amaryl) είναι διαθέσιμο από του στόματος, μέσης και μακράς δράσης, το οποίο ανήκει στις . Μερικές φορές είναι ταξινομημένη ως η πρώτη τρίτης γενιάς σουλφονυλουρία, και μερικές ως δεύτερης γενιάς. (el)</li> <li style="display:none;">Glimepirid ist ein orales Antidiabetikum aus der Stoffgruppe der Sulfonylharnstoffe, welches in den β-Zellen der Bauchspeicheldrüse die Insulinfreisetzung steigert und in der Therapie des Diabetes mellitus Typ 2 eingesetzt wird. Der Wirkstoff wurde 1981 von Hoechst als Antidiabetikum und 1994 zur Behandlung von Atherosklerose patentiert. (de)</li> <li>Glimepiride, is an anti-diabetic medication used to treat type 2 diabetes. It is less preferred than metformin. Use is recommended together with diet and exercise. It is taken by mouth. Glimepiride takes up to three hours for maximum effect and lasts for about a day. Common side effects include headache, nausea, and dizziness. Serious side effects may include low blood sugar. Use during pregnancy and breastfeeding is not recommended. It works mainly by increasing the amount of insulin released from the pancreas. It is classified as a second-generation sulfonylurea. Glimepiride was patented in 1979 and approved for medical use in 1995. It is available as a generic medication. In 2020, it was the 87th most commonly prescribed medication in the United States, with more than 8 million prescriptions. (en)</li> <li style="display:none;">La glimepirida es un medicamento antidiabético oral de la clase de las sulfonilureas de segunda generación—ocasionalmente considerada de tercera generación—, indicado en el tratamiento de la diabetes mellitus tipo 2, especialmente en pacientes cuya hiperglicemia no puede ser controlada solamente con modificaciones dietéticas. Se vende comercialmente en dosis de 2 y 4 mg, cuya acción dura entre 16 y 24 horas, indicándose entre 1 y 8 mg diarios. (es)</li> <li style="display:none;">Glimepirid, adalah obat yang biasa digunakan untuk penanganan penyakit diabetes melitus tipe 2 . Obat ini lebih jarang digunakan daripada obat metformin . Glimepiride memerlukan tiga jam setelah diminum untuk mencapai efek maksimal dan efek ini berlangsung hingga satu hari. Efek samping yang umum dialami pengguna antara lain sakit kepala, mual, dan pusing berputar. Efek samping yang sangat serius termasuk ke dalamnya antara lain gejala-gejala hipoglikemia . Penggunaan glimepirid ini selama kehamilan tidak dianjurkan dan termasuk ke dalam kategori C. Obat ini juga tidak dianjurkan digunakan oleh ibu menyusui karena seperti halnya obat-obat golongan sulfonilurea, obat ini dapat diekskresikan ke dalam air susu. Obat ini berkerja dengan meningkatkan kadar insulin yang dihasilkan oleh pankreas . Obat ini diklasifikasikan sebagai obat golongan sulfonilurea generasi kedua. Glimepirid ini dipatenkan pada tahun 1979 dan disetujui untuk penggunaan secara medis pada tahun 1995. Obat ini juga tersedia sebagai obat generik . Pada tahun 2018, glimepirid ini adalah obat ke-71 yang paling sering diresepkan di Amerika Serikat, dengan lebih dari 11 juta resep. (in)</li> <li style="display:none;">글리메피리드(Glimepiride)는 당뇨병(Diabetes) 중에서 인슐린 분비는 정상이나, 인슐린에 저항성을 가지는 제 2형 당뇨병을 치료하는 약물이다. (ko)</li> <li style="display:none;">グリメピリド（Glimepiride）は、スルホニルウレア(SU)系の経口血糖降下薬の一つ。などの腎排泄型の第1世代やグリクラジドなどの胆汁排泄型の第2世代との対比から、第3世代のSU薬とも呼ばれる。商品名アマリール。 (ja)</li> <li style="display:none;">Glimepiride is een geneesmiddel dat sinds 1995 internationaal op de markt op recept verkrijgbaar is en behoort tot de groep geneesmiddelen die sulfonylureumderivaten (afgeleiden van sulfonylureum) worden genoemd. Sulfonylureumderivaten stimuleren de afgifte van insuline door de β-cellen in het pancreas (alvleesklier) en zorgen hierdoor voor een verminderde hoeveelheid glucose in het bloed. Het middel wordt voorgeschreven bij patiënten met diabetes mellitus type 2 (DM 2). Bij deze vorm van diabetes mellitus is er sprake van een insulineresistentie. Dit in tegenstelling tot diabetes mellitus type 1; hier is sprake van een gestoorde aanmaak van insuline. DM 2 presenteert zich meestal bij mensen van Europese oorsprong boven het 40e levensjaar. Van de patiënten heeft 80% overgewicht. Voor behandeling van DM 2 is een dieet vaak voldoende. Na herstel van het overgewicht, herstelt het glucosemetabolisme zich immers meestal vanzelf. Wanneer hierbij onvoldoende resultaat wordt bewerkstelligd, wordt er overgegaan tot voorschrijven van tabletten glimepiride en/of metformine. Bij enkele uitzonderingen wordt er tevens overgegaan tot het starten van insuline spuiten: * C-peptide <1 ng/ml * Bij ziekenhuisopname * Bij herhaaldelijke infecties * Bij een te hoog , ondanks de maximale dosis orale anti-diabetica * Wanneer er frequent bloedsuiker spiegels van >12 mmol/L worden bereikt (nl)</li> <li style="display:none;">Glimepiryd (łac. Glimepiridum) – organiczny związek chemiczny, lek hipoglikemizujący, pochodna sulfonylomocznika. (pl)</li> <li style="display:none;">A glimepirida é um antidiabético pertecente ao grupo das sulfoniluréias. (pt)</li> <li style="display:none;">格列美脲（英語：Glimepiride），為一種用以治療第二型糖尿病的藥物，目前做為二甲双胍的後線藥物。使用本品者，建議輔以飲食和運動。格列美脲為口服藥物，服用後三小時會達到最大藥效，藥效約可持續一天。格列美脲常見的副作用為頭痛、噁心及頭暈，其他嚴重的副作用為低血糖。懷孕或哺乳者，不建議使用本藥物。本品的作用機轉，主要為促進胰臟分泌胰島素；格列美脲為第二代的磺酰脲类（Sulfonylurea）藥物。 1979年，格列美脲獲得專利，於1995年核准為醫療用途。本品已有學名藥於市面流通，2019年，格列美脲在美國處方藥物中排行第62名，共開立超過1100萬劑。 (zh)</li> <li style="display:none;">Глімепірид (англ. Glimepiride, лат. Glimepiridum) — таблетований цукрознижуючий лікарський засіб класу сульфонамідів для прийому всередину. Глімепірид розроблений у 1979 році в лабораторії компанії «Sanofi»., та застосовується у клінічній практиці з 1995 року. (uk)</li> <li style="display:none;">Глимепирид — гипогликемическое лекарственное средство, происзводное сульфонилмочевины третьего поколения. В терапии сахарного диабета глимепирид менее предпочтителен, чем метформин. Его рекомендуется использовать вместе с диетой и физическими упражнениями. Эффект от перорального приёма глимепирида достигает максимума в течение трёх часов и длится около суток. Глимепирид работает в основном за счет увеличения количества инсулина, выделяемого из поджелудочной железы. Общие побочные эффекты от его приёма включают головную боль, тошноту и головокружение. Серьезные побочные эффекты могут включать низкий уровень сахара в крови. Использование во время беременности и кормления грудью не рекомендуется. Глимепирид был запатентован в 1979 году и одобрен[где?] для медицинского применения в 1995 году. 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resource="http://umbel.org/umbel/rc/DrugProduct" href="http://umbel.org/umbel/rc/DrugProduct">umbel-rc:DrugProduct</a></li> </ul></td></tr><tr class="even"><td class="col-2"><a class="uri" href="http://www.w3.org/2000/01/rdf-schema#comment">rdfs:comment</a> </td><td class="col-10 text-break"><ul> <li style="display:none;">جليميبرايد (بالإنجليزية: Glimepiride)‏ ويعرف بالأسماء التجارية دولسيل (بالإنجليزية: Dolcyl)‏ هو دواء يستخذم لعلاج داء السكري، يؤخد عن طريق الفم. (ar)</li> <li style="display:none;">Η γλιμεπιρίδη (glimepiride, αρχική επωνυμία Amaryl) είναι διαθέσιμο από του στόματος, μέσης και μακράς δράσης, το οποίο ανήκει στις . Μερικές φορές είναι ταξινομημένη ως η πρώτη τρίτης γενιάς σουλφονυλουρία, και μερικές ως δεύτερης γενιάς. (el)</li> <li style="display:none;">Glimepirid ist ein orales Antidiabetikum aus der Stoffgruppe der Sulfonylharnstoffe, welches in den β-Zellen der Bauchspeicheldrüse die Insulinfreisetzung steigert und in der Therapie des Diabetes mellitus Typ 2 eingesetzt wird. Der Wirkstoff wurde 1981 von Hoechst als Antidiabetikum und 1994 zur Behandlung von Atherosklerose patentiert. (de)</li> <li style="display:none;">La glimepirida es un medicamento antidiabético oral de la clase de las sulfonilureas de segunda generación—ocasionalmente considerada de tercera generación—, indicado en el tratamiento de la diabetes mellitus tipo 2, especialmente en pacientes cuya hiperglicemia no puede ser controlada solamente con modificaciones dietéticas. Se vende comercialmente en dosis de 2 y 4 mg, cuya acción dura entre 16 y 24 horas, indicándose entre 1 y 8 mg diarios. (es)</li> <li style="display:none;">글리메피리드(Glimepiride)는 당뇨병(Diabetes) 중에서 인슐린 분비는 정상이나, 인슐린에 저항성을 가지는 제 2형 당뇨병을 치료하는 약물이다. (ko)</li> <li style="display:none;">グリメピリド（Glimepiride）は、スルホニルウレア(SU)系の経口血糖降下薬の一つ。などの腎排泄型の第1世代やグリクラジドなどの胆汁排泄型の第2世代との対比から、第3世代のSU薬とも呼ばれる。商品名アマリール。 (ja)</li> <li style="display:none;">Glimepiryd (łac. Glimepiridum) – organiczny związek chemiczny, lek hipoglikemizujący, pochodna sulfonylomocznika. (pl)</li> <li style="display:none;">A glimepirida é um antidiabético pertecente ao grupo das sulfoniluréias. (pt)</li> <li style="display:none;">格列美脲（英語：Glimepiride），為一種用以治療第二型糖尿病的藥物，目前做為二甲双胍的後線藥物。使用本品者，建議輔以飲食和運動。格列美脲為口服藥物，服用後三小時會達到最大藥效，藥效約可持續一天。格列美脲常見的副作用為頭痛、噁心及頭暈，其他嚴重的副作用為低血糖。懷孕或哺乳者，不建議使用本藥物。本品的作用機轉，主要為促進胰臟分泌胰島素；格列美脲為第二代的磺酰脲类（Sulfonylurea）藥物。 1979年，格列美脲獲得專利，於1995年核准為醫療用途。本品已有學名藥於市面流通，2019年，格列美脲在美國處方藥物中排行第62名，共開立超過1100萬劑。 (zh)</li> <li style="display:none;">Глімепірид (англ. Glimepiride, лат. Glimepiridum) — таблетований цукрознижуючий лікарський засіб класу сульфонамідів для прийому всередину. Глімепірид розроблений у 1979 році в лабораторії компанії «Sanofi»., та застосовується у клінічній практиці з 1995 року. (uk)</li> <li>Glimepiride, is an anti-diabetic medication used to treat type 2 diabetes. It is less preferred than metformin. Use is recommended together with diet and exercise. It is taken by mouth. Glimepiride takes up to three hours for maximum effect and lasts for about a day. Common side effects include headache, nausea, and dizziness. Serious side effects may include low blood sugar. Use during pregnancy and breastfeeding is not recommended. It works mainly by increasing the amount of insulin released from the pancreas. It is classified as a second-generation sulfonylurea. (en)</li> <li style="display:none;">Glimepirid, adalah obat yang biasa digunakan untuk penanganan penyakit diabetes melitus tipe 2 . Obat ini lebih jarang digunakan daripada obat metformin . Glimepiride memerlukan tiga jam setelah diminum untuk mencapai efek maksimal dan efek ini berlangsung hingga satu hari. Glimepirid ini dipatenkan pada tahun 1979 dan disetujui untuk penggunaan secara medis pada tahun 1995. Obat ini juga tersedia sebagai obat generik . Pada tahun 2018, glimepirid ini adalah obat ke-71 yang paling sering diresepkan di Amerika Serikat, dengan lebih dari 11 juta resep. (in)</li> <li style="display:none;">Glimepiride is een geneesmiddel dat sinds 1995 internationaal op de markt op recept verkrijgbaar is en behoort tot de groep geneesmiddelen die sulfonylureumderivaten (afgeleiden van sulfonylureum) worden genoemd. Sulfonylureumderivaten stimuleren de afgifte van insuline door de β-cellen in het pancreas (alvleesklier) en zorgen hierdoor voor een verminderde hoeveelheid glucose in het bloed. Het middel wordt voorgeschreven bij patiënten met diabetes mellitus type 2 (DM 2). Bij deze vorm van diabetes mellitus is er sprake van een insulineresistentie. Dit in tegenstelling tot diabetes mellitus type 1; hier is sprake van een gestoorde aanmaak van insuline. DM 2 presenteert zich meestal bij mensen van Europese oorsprong boven het 40e levensjaar. Van de patiënten heeft 80% overgewicht. (nl)</li> <li style="display:none;">Глимепирид — гипогликемическое лекарственное средство, происзводное сульфонилмочевины третьего поколения. В терапии сахарного диабета глимепирид менее предпочтителен, чем метформин. Его рекомендуется использовать вместе с диетой и физическими упражнениями. Эффект от перорального приёма глимепирида достигает максимума в течение трёх часов и длится около суток. Глимепирид был запатентован в 1979 году и одобрен[где?] для медицинского применения в 1995 году. (ru)</li> </ul></td></tr><tr class="odd"><td class="col-2"><a class="uri" href="http://www.w3.org/2000/01/rdf-schema#label">rdfs:label</a> </td><td class="col-10 text-break"><ul> <li style="display:none;">جليميبرايد (ar)</li> <li style="display:none;">Glimepirid (de)</li> <li style="display:none;">Γλιμεπιρίδη (el)</li> <li>Glimepiride (en)</li> <li style="display:none;">Glimepirida (es)</li> <li style="display:none;">Glimepirid (in)</li> <li style="display:none;">글리메피리드 (ko)</li> <li style="display:none;">Glimepiride (nl)</li> <li style="display:none;">グリメピリド (ja)</li> <li style="display:none;">Glimepiryd (pl)</li> <li style="display:none;">Glimepirida (pt)</li> <li style="display:none;">Глимепирид (ru)</li> <li style="display:none;">格列美脲 (zh)</li> <li style="display:none;">Глімепірид (uk)</li> </ul></td></tr><tr class="even"><td class="col-2"><a class="uri" href="http://www.w3.org/2002/07/owl#sameAs">owl:sameAs</a> </td><td class="col-10 text-break"><ul> <li><a class="uri" 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