干细胞移植

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<div class="row"> <div class="col-sm-12"> <h1 class="font-size-30 fweight-400 color-white">再生医学杂志 </h1> </div> </div> </div> </div> <nav class="navbar navbar-expand-lg bg-navbar navbar-light mega-menu journal-menu topbar-shadow" id="mainNavbar"> <div class="container"> <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-center" id="navbarSupportedContent"> <ul class="navbar-nav mb-auto mb-2 mb-lg-0"> <li class="nav-item"><a class="nav-link" href="https://chinese.scitechnol.com/journals/regenerative-medicine.html" title="点击这里"><i class="fa fa-home" aria-hidden="true"></i></a></li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown" role="button" data-bs-toggle="dropdown" 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style="vertical-align: inherit;"><font style="vertical-align: inherit;">干细胞移植的类型</font></font></strong></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">干细胞移植有两种主要类型：</font></font></p> <p style="text-align: justify;"><strong><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">自体移植（AUTO）。</font></font></strong><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">接受 AUTO 移植的患者接受他或她自己的干细胞。在自动移植过程中，收集患者的干细胞，然后将其储存在特殊的冰箱中，可以保存数十年。通常，患者在接下来的一周接受大剂量的化疗和/或放射治疗，然后将冷冻的干细胞解冻并注入患者的静脉中。干细胞通常会在血液中保留约 24 小时，直到它们进入骨髓空间，在那里生长和繁殖，开始愈合过程。</font></font></p> <p style="text-align: justify;"><strong><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">同种异体移植（ALLO）。</font></font></strong><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">接受 ALLO 移植的患者接受另一个人捐赠的干细胞。因此，ALLO 移植的第一步是找到匹配的供体。称为人类白细胞抗原 (HLA) 的特定蛋白质存在于白细胞表面和全身各处。这些蛋白质的组合使每个人的组织都是独一无二的。 HLA 分型是一种特殊的血液测试，可识别这些蛋白质。成功的骨髓移植需要捐赠近乎完美的 HLA 匹配骨髓。在移植过程中给予人体的 HLA 匹配的造血干细胞不太可能导致移植物抗宿主病（GVHD，一种并发症，移植骨髓中的免疫细胞将受体身体视为异物并对其进行攻击）。兄弟姐妹（兄弟姐妹）通常最有可能完全匹配。有时，其他家庭成员也可以匹配。在某些情况下，无关的志愿者捐赠者可能是最佳匹配。了解有关捐献骨髓的更多信息。</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">一旦确定了捐赠者，就会协调干细胞捐赠，以便尽可能在患者初始化疗和/或放射治疗结束时进行。移植当天，患者通过静脉注射接收未冷冻的捐赠干细胞，并将其输送到他或她的静脉中。</font></font></p> </div> </div>  <div class="col-xs-12 col-md-3"> <div class="divider-v4 divider-v4-left-double bg-color-white padding-10 margin-b-10"> <h2 class="divider-v4-title">探索科技</h2> <div> <ul class="list-unstyled angle-right"> <li class="color-base"><a href="https://chinese.scitechnol.com/author-guidelines.html" title="点击这里"> 作者指南</a></li> <li class="color-base"><a href="https://chinese.scitechnol.com/reviewer-guidelines.html" title="点击这里"> 审稿人指南</a></li> <li class="color-base"><a href="https://chinese.scitechnol.com/scitechnol-associations-indexing.html" title="点击这里"> 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