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href="/web/20130522021345/http://www.healio.com/rheumatology"> Rheumatology</a> </p> <!-- /breadcrumbs --> <!-- breaking news --> <div id="breaking-news" class="breaking-news"> <h2> <a id="layout_0_phmaincontent_1_hlTitle" href="/web/20130522021345/http://www.healio.com/rheumatology/rheumatoid-arthritis/news/online/{5300FAF6-D0A3-402C-923F-A57ED514EC36}/Sandoz-conducting-recall-of-methotrexate-sodium">Sandoz conducting recall of methotrexate sodium</a> </h2> <ul class="meta-info"> <li> May 21, 2013</li> </ul> <!-- figure --> <!-- /figure --> <p> <p>Sandoz is conducting a voluntary, nationwide recall of two lots of its methotrexate sodium, USP, 25 mg/mL, 40 mL vial injectable drug because it discovered particulate matter in some vials, the FDA announced today.</p> <p>“Parenteral injection … from affected lots can lead to microembolization in areas where the particles lodge,” a press release stated. Sandoz discovered the issue during a routine quality examination of retention samples. Sandoz is unaware of any related adverse events, and clinical symptoms were not expected from the microemboli, according to the manufacturer.</p><a id="layout_0_phmaincontent_1_hlFullStory" class="jump-link" href="/web/20130522021345/http://www.healio.com/rheumatology/rheumatoid-arthritis/news/online/{5300FAF6-D0A3-402C-923F-A57ED514EC36}/Sandoz-conducting-recall-of-methotrexate-sodium">Full Story <span>»</span></a> </p> <script language="javascript" type="text/javascript"> // ESS 11/29/2012: Put this code back in when we're ready to make the "Full Story>>" link move into the teaser paragraph // Also add this to the class name of the full story hyperlink "breaking-news-more" /*$j(document).ready(function () { $j('div + a.breaking-news-more, p + a.breaking-news-more').each(function () { $j(this).prev().append($j(this)); }); });*/ </script> <!-- news tabs --> <div id="tabs" class="news-tab-group"> <ul class="tabs"> <li><a href="#tab-headlines">Headlines</a></li> <li><a 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href="/web/20130522021345/http://www.healio.com/rheumatology/systemic-lupus-erythematosus/news/online/{53864658-FAAF-444E-B493-4ED6F9BF14F1}/Childhood-onset-SLE-patients-displayed-differences-in-brain-activation-patterns"> Childhood-onset SLE patients displayed differences in brain activation patterns</a></h4> </li> <li class="meta-info"> May 20, 2013</li> </ul> <ul> <li><a href="/web/20130522021345/http://www.healio.com/rheumatology/news" id="layout_0_phmaincontent_1_MoreHeadlines" class="jump-link">More <span>»</span></a></li></ul> </div> <!-- pane 2 --> <div id="tab-mostpopular" class="panes"> <ul> <li> <h4> <a href="/web/20130522021345/http://www.healio.com/rheumatology/rheumatoid-arthritis/news/online/{5300FAF6-D0A3-402C-923F-A57ED514EC36}/Sandoz-conducting-recall-of-methotrexate-sodium"> Sandoz conducting recall of methotrexate sodium</a></h4> </li> <li class="meta-info"> May 21, 2013</li> </ul> <ul> <li> <h4> <a href="/web/20130522021345/http://www.healio.com/rheumatology/fibromyalgia/news/online/{490880F0-DC1B-4BD3-97FB-C5FC8647C5FD}/New-Canadian-guidelines-for-fibromyalgia-reviewed"> New Canadian guidelines for fibromyalgia reviewed</a></h4> </li> <li class="meta-info"> May 21, 2013</li> </ul> <ul> <li> <h4> <a href="/web/20130522021345/http://www.healio.com/rheumatology/systemic-lupus-erythematosus/news/online/{53864658-FAAF-444E-B493-4ED6F9BF14F1}/Childhood-onset-SLE-patients-displayed-differences-in-brain-activation-patterns"> Childhood-onset SLE patients displayed differences in brain activation patterns</a></h4> </li> <li class="meta-info"> May 20, 2013</li> </ul> <ul> <li><a href="/web/20130522021345/http://www.healio.com/rheumatology/news/most-popular" id="layout_0_phmaincontent_1_MoreMostPopular" class="jump-link">More <span>»</span></a></li></ul> </div> <!-- pane 3 --> <div id="tab-fromthepodium" class="panes"> <ul> <li> <h4> <a href="/web/20130522021345/http://www.healio.com/orthopedics/knee/news/online/{A5859216-3A28-4ACC-8DC4-FD2E227F0F12}/Study-TKR-improves-long-term-quality-of-life-for-patients-with-juvenile-idiopathic-arthritis"> Study: TKR improves long-term quality of life for patients with juvenile idiopathic arthritis </a> </h4> </li> <li class="meta-info"> April 2, 2013 </li> </ul> <ul> <li> <h4> <a href="/web/20130522021345/http://www.healio.com/rheumatology/systemic-lupus-erythematosus/news/online/{82A9AEDD-B065-4A76-8605-755BF0350008}/Anorexia-nervosa-might-be-marker-of-neuropsychiatric-SLE-"> Anorexia nervosa might be marker of neuropsychiatric SLE </a> </h4> </li> <li class="meta-info"> March 14, 2013 </li> </ul> <ul> <li> <h4> <a href="/web/20130522021345/http://www.healio.com/dermatology/practice-management/news/online/{4DC4E647-5BC9-4957-8E72-06D2A531D7E6}/AAD-app-for-psoriasis-psoriatic-arthritis-now-available"> AAD app for psoriasis, psoriatic arthritis now available </a> </h4> </li> <li class="meta-info"> March 1, 2013 </li> </ul> <ul> <li><a href="/web/20130522021345/http://www.healio.com/rheumatology/news/meeting-news-coverage" id="layout_0_phmaincontent_1_MoreFtp" class="jump-link">More <span>»</span></a></li></ul> </div> </div> </div> <!-- /breaking news --> <div id="personalized-content"> <h4 class="pc-bar"> Personalize your page! </h4> <p> Register for Healio to get content tailored to your specialty and areas of interest. It’s FREE and only takes one minute. <a id="layout_0_phmaincontent_2_RegisterNow" href="/web/20130522021345/http://www.healio.com/footer/account-information/login">Register now!</a></p> </div> <!-- video content --> <div id="video-channel"> <iframe src="https://web.archive.org/web/20130522021345if_/http://video.healio.com/embed/player/6MJ3TM0VSWFV68PQ" width="488" height="240" frameborder="0" marginheight="0" marginwidth="0" scrolling="no" allowtransparency="true"></iframe> </div> <!-- /video content --> <!-- silo content --> <div id="silo-content"> <div class="module-box-alt left"> <ul> <li class="title">Fibromyalgia</li> <li class="img"><a href="/web/20130522021345/http://www.healio.com/rheumatology/fibromyalgia/news/online/{BA07243C-2DE5-4210-A590-DD04C28902E4}/Creatine-supplements-improved-muscle-function-in-fibromyalgia-patients"> <img src="/web/20130522021345im_/http://www.healio.com/~/media/Images/silos/Rheumatology/2013/05_May/Gualano_Bruno_PhD.gif" alt="Bruno Gualano, PhD" width="90" height="120"/></a></li> <li><strong><a href="/web/20130522021345/http://www.healio.com/rheumatology/fibromyalgia/news/online/{BA07243C-2DE5-4210-A590-DD04C28902E4}/Creatine-supplements-improved-muscle-function-in-fibromyalgia-patients"> Creatine and muscle function</a></strong></li> <li class="meta-info"> Supplementation increased muscle function, "but it had only a minor effect on general symptoms of fibromyalgia,” Bruno Gualano, PhD, said.</li> </ul> <a class="jump-link" href="/web/20130522021345/http://www.healio.com/rheumatology/fibromyalgia/news/online/{BA07243C-2DE5-4210-A590-DD04C28902E4}/Creatine-supplements-improved-muscle-function-in-fibromyalgia-patients">More <span>»</span></a> </div> <div class="module-box-alt right"> <ul> <li class="title">Healio Minute, May 21, 2013</li> <li class="img"><a href="/web/20130522021345/http://www.healio.com/news/online/{4077B425-9B6A-4CD3-9CFB-695C612C53E9}/Healio-Minute-Tuesday-May-21-2013-Edition-Timing-of-first-drink-really-matters-CMS-floats-trial-observation-balloon-healthy-providers-give-best-hypertension-advice"> <img src="/web/20130522021345im_/http://www.healio.com/~/media/Images/silos/Healio/121631_Healio Minute opt2_70px.jpg" alt="Healio Minute logo" width="70" height="90"/></a></li> <li><strong><a href="/web/20130522021345/http://www.healio.com/news/online/{4077B425-9B6A-4CD3-9CFB-695C612C53E9}/Healio-Minute-Tuesday-May-21-2013-Edition-Timing-of-first-drink-really-matters-CMS-floats-trial-observation-balloon-healthy-providers-give-best-hypertension-advice"> First drink, new rule, best advice</a></strong></li> <li class="meta-info"> Timing of first drink really matters, CMS floats trial “observation” balloon and healthy providers give best hypertension advice.</li> </ul> <a class="jump-link" href="/web/20130522021345/http://www.healio.com/news/online/{4077B425-9B6A-4CD3-9CFB-695C612C53E9}/Healio-Minute-Tuesday-May-21-2013-Edition-Timing-of-first-drink-really-matters-CMS-floats-trial-observation-balloon-healthy-providers-give-best-hypertension-advice">More <span>»</span></a> </div> <div class="module-box-alt left"> <ul> <li class="title">Health Care Legislative and Regulatory Update</li> <li class="img"><a href="/web/20130522021345/http://www.healio.com/news/online/{EC82758C-D56D-42B7-994F-63E7B0D27B8F}/BLOG-Inpatient-admission-or-observation-services-Do-we-finally-have-some-clarity"> <img src="/web/20130522021345im_/http://www.healio.com/~/media/Images/silos/Healio/Lotchin Theodore SILO.jpg" alt="Theodore_Lotchin_color" width="70" height="90"/></a></li> <li><strong><a href="/web/20130522021345/http://www.healio.com/news/online/{EC82758C-D56D-42B7-994F-63E7B0D27B8F}/BLOG-Inpatient-admission-or-observation-services-Do-we-finally-have-some-clarity"> Inpatient admission vs. observation services</a></strong></li> <li class="meta-info"> Will recently proposed rule finally add some clarity? By <em>Ted Lotchin</em>.</li> </ul> <a class="jump-link" href="/web/20130522021345/http://www.healio.com/news/online/{EC82758C-D56D-42B7-994F-63E7B0D27B8F}/BLOG-Inpatient-admission-or-observation-services-Do-we-finally-have-some-clarity">More <span>»</span></a> </div> <div class="module-box-alt right"> <ul> <li class="title">Genomics</li> <li class="img"><a href="/web/20130522021345/http://www.healio.com/rheumatology/rheumatoid-arthritis/news/online/{7D97709D-DA92-405D-9A06-6D07AD2F23C8}/New-genomics-center-to-focus-on-RA-lupus"> <img src="/web/20130522021345im_/http://www.healio.com/~/media/Images/silos/Rheumatology/2013/04_April/Ivashkiv_Lionel_B_MD.gif" alt="Lionel B. Ivashkiv, MD" width="90" height="120"/></a></li> <li><strong><a href="/web/20130522021345/http://www.healio.com/rheumatology/rheumatoid-arthritis/news/online/{7D97709D-DA92-405D-9A06-6D07AD2F23C8}/New-genomics-center-to-focus-on-RA-lupus"> Focus on RA, Lupus</a></strong></li> <li class="meta-info"> "We are very excited to try to understand how genes involved in lupus and rheumatoid arthritis are regulated," Lionel B. 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