<?xml version="1.0" encoding="UTF-8"?> <article key="pdf/15475" mdate="2009-08-28 00:00:00"> <author>S茅rgio F. Sousa and Nuno M. F. S. A. Cerqueira and Marta A. S. Perez and Irina S. Moreira and Ant贸nio J. M.Ribeiro and Ana R. A. P. Neves and Maria J. Ramos and Pedro A. Fernandes</author> <title>Recent Advances on Computational Proteomics</title> <pages>404 - 414</pages> <year>2009</year> <volume>3</volume> <number>8</number> <journal>International Journal of Biomedical and Biological Engineering</journal> <ee>https://publications.waset.org/pdf/15475</ee> <url>https://publications.waset.org/vol/32</url> <publisher>World Academy of Science, Engineering and Technology</publisher> <abstract>In this work we report the recent progresses that have been achieved by our group in the last half decade on the field of computational proteomics. Specifically, we discuss the application of Molecular Dynamics Simulations and Electronic Structure Calculations in drug design, in the clarification of the structural and dynamic properties of proteins and enzymes and in the understanding of the catalytic and inhibition mechanism of cancerrelated enzymes. A set of examples illustrate the concepts and help to introduce the reader into this important and fast moving field. </abstract> <index>Open Science Index 32, 2009</index> </article>