Jubilant Biosys Limited on LinkedIn: #cro #crdmo #cdmo #computationalchemistry #drugdesign #pharmainnovation…

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By combining molecular modeling, pharmacophore design, and QSAR analysis, we provide precise, rational based drug discovery support that accelerates research outcomes. Please write to: <a class="link" href="mailto:bd@jubilantbiosys.com?trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>bd@jubilantbiosys.com</a> to know more about our computational chemistry services or click here: <a class="link" href="https://lnkd.in/d8kaac9n?trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/d8kaac9n</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcro&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CRO</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcrdmo&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" 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Passionate about career growth in pharma. Follow for the latest job updates and opportunities in these fields. Let's connect! 🌟</p> <span class="text-xs text-color-text-low-emphasis comment__duration-since absolute right-6 top-1 inline-block"> 1w </span> <div class="ellipsis-menu absolute right-0 top-0 !mr-0.5 babybear:!-top-0.5" data-test-id="comment__ellipsis-menu" data-feed-action="show-comment-dropdown"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] ellipsis-menu__trigger--small w-[32px] h-[32px] babybear:rotate-90 mamabear:!h-4 mamabear:!min-h-[32px] papabear:!h-4 papabear:!min-h-[32px]" aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_comment_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/c26vw8uiog92lvrqov98hvbxr"></icon> </button> <ul class="collapsible-dropdown__list 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class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">Can others use ADPS smart DNA polymerase? Of course, Yes! ADPS smart DNA polymerase IP belongs to GENECAST. However, we hope that more diagnostic companies adopting this polymerase and develop high quality assays. We believe that this is the improve the human health care technology. Of course, some companies already developing new diagnostic technology using ADPS polymerase and some are in a negotiation. Unfortunately, I can’t open the companies (because it’s a top secret) If you like to upgrade your molecular diagnostic technology or product, Hurry up! More and more companies are coming for ADPS polymerase. Ask sample of ADPS polymerase. <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Finnovativednapolymerase&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#InnovativeDNApolymerase</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2FelimiateAbRbackgroundnoise&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#elimiate_backgroundnoise</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhighsensitivity&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#highsensitivity</a> <a class="link" 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These features are poised to play a pivotal role in drug–target interactions. The inherent polarity of triazole contributes to its lower logP, suggesting the potential improvement in water solubility. The metabolic stability of triazole adds additional value to drug discovery. Moreover, the metal-binding capacity of the nitrogen atom lone pair electrons of triazole has broad applications in the development of metal chelators and antifungal agents. This Perspective aims to underscore the unique physicochemical attributes of triazole and its application. 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Optimizing molecules for drug discovery is often a tedious and costly process. However, by implementing automation and miniaturization directly into biological assays, we can accelerate synthesis, save expensive reagents, and eliminate the need for extensive single-compound purification and handling. This innovative approach is commonly known as plate-based chemistry or direct-to-biology. In addition to classical small molecules, this method has been successfully applied to new modalities like PROTACs. At the upcoming EFMC-ISMC 2024, where we will showcase a proof-of-principle case study demonstrating automated reaction miniaturization of amide couplings, followed by direct biological readouts of unpurified reaction mixtures. 🌐Curious about the details? 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text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 8mo  </time>  </span> </div>  </div> </div> <div class="ellipsis-menu absolute right-0 top-0 main-feed-activity-card__ellipsis-menu !top-auto !relative !mr-1" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/671xosfpvk4c0kqtyl87hashi"></icon> </button> <ul class="collapsible-dropdown__list hidden container-raised absolute w-auto overflow-y-auto flex-col items-stretch z-1 bottom-auto top-[100%]" role="menu" tabindex="-1"> <li 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This engaging opinionated review in Drug Discovery Today tackles this question head-on. A key takeaway is that this chemical domain is more accurately delineated by 3D descriptors rather than 2D ones. This is chiefly because chameleonicity is not adequately represented by 2D descriptors. And recall with Chamelogk we can easily measure chameleonicity in our lab ... Thanks to the Uppsala guys (<a class="link" href="https://se.linkedin.com/in/jan-kihlberg-862a674?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Jan Kihlberg</a>, <a class="link" href="https://se.linkedin.com/in/nathan-poongavanam-3b60b78?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Nathan Poongavanam</a>, <a class="link" href="https://se.linkedin.com/in/mateerdelyi?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Mate Erdelyi</a>, <a class="link" href="https://se.linkedin.com/in/yoseph-atilaw-0434a63b?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Yoseph Atilaw</a>) and, of course, to my Dream Team (<a class="link" href="https://it.linkedin.com/in/giulia-apprato?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Giulia Apprato</a>, <a class="link" href="https://cz.linkedin.com/in/diego-garc%C3%ADa-jim%C3%A9nez-4134a7175?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Diego García Jiménez</a>, <a class="link" href="https://it.linkedin.com/in/giuseppe-ermondi-3200235?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Giuseppe Ermondi</a>) <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fbioavailability&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#bioavailability</a>, <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fprotac&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#protac</a>, <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fchameleonicity&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#chameleonicity</a>, <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fchamelogk&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#Chamelogk</a>, <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2F3d&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#3d</a>, <a class="link" 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href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdrugdiscovery&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#DrugDiscovery</a> process? <a class="link" href="https://nl.linkedin.com/company/symeresbv?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Symeres</a> is your trusted partner in delivering high-quality <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmedicinalchemistry&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#MedicinalChemistry</a> services, from <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fhitidentification&trk=public_post-text" target="_self" 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The importance of pairing affinity and reactivity elements in screening sets is also discussed. It resonates with us the few selective probes available in the public domain to enable target-specific assays. Something we have successfully enabled at Covant, for thousands of proteins (targets of interest and, importantly, anti- and off-targets). The authors also discuss the importance of enabling structure-based design, through crystallography if possible, to confirm the site of labelling. We are believers in leveraging all tools at our disposal and, in the absence of (or complementing) X-Ray data, obtaining ligand-protein interaction information through additional techniques, such as structural proteomics (e.g., HDX-MS). Combined with applied modeling these provide important details about the binding site and dynamic conformation of the protein, +/-adduct formation, to accelerate D-M-T-A cycles. The dynamic nature of covalent bond formation advises against relying heavily on traditional equilibrium-based potency, using kinact/KI to drive SAR more efficiently. <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcovalency&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#covalency</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdrugdiscovery&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#drugdiscovery</a></p>  </div>  <a href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Fwww%2Esciencedirect%2Ecom%2Fscience%2Farticle%2Fpii%2FS2472555224000042&urlhash=6Smy&trk=public_post_feed-article-content" target="_self" data-tracking-control-name="public_post_feed-article-content" 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Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality." Changes made to the <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fbioprocess&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#bioprocess</a> can be linked to product quality attributes, but only if there are frequent data points to show the development throughout the bioprocess. Access to good product quality data at frequent timepoints from a full bioprocess can be a tall order for the analytical department. In this <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fwebinar&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#webinar</a>, experts from <a class="link" href="https://www.linkedin.com/company/908-devices?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>908 Devices</a>, will present a simple dilute-and-shoot analysis using ZipChip capillary <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Felectrophoresis&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#electrophoresis</a> separation coupled to a high-resolution <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fmassspectrometer&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#massspectrometer</a> and a case study where a comparison of <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcho&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#CHO</a> fed-batch process runs with the usual daily bolus glucose feed strategy and a 2g/L dynamic glucose feed strategy, enabled by MAVEN monitoring and control, resulting in clear improvement in product quality profile. Date: Tues., November 19th. Time: 11 AM ET. Featuring: <a class="link" href="https://www.linkedin.com/in/redmanerin?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Erin Redman</a>, PhD, principal scientist & <a class="link" href="https://www.linkedin.com/in/graziella-piras-5595a54?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>Graziella Piras</a>, PhD, senior director of strategic marketing, life science, <a class="link" href="https://www.linkedin.com/company/908-devices?trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>908 Devices</a>. Register Now: <a class="link" href="https://lnkd.in/gNGJ6fyn?trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/gNGJ6fyn</a></p>  </div>  <a href="https://www.linkedin.com/redir/redirect?url=https%3A%2F%2Fbpi%2Ebioprocessintl%2Ecom%2Flinking-mab-product-quality-profile-changes-to-your-bioprocess-case-study-of-dynamic-glucose-level-control-in-cho-process-improves-product-quality&urlhash=IlvC&trk=public_post_feed-article-content" target="_self" data-tracking-control-name="public_post_feed-article-content" data-tracking-will-navigate class="flex flex-col feed-article-content" data-test-id="article-content"> <img alt="Linking mAb Product Quality Profile Changes to Your Bioprocess: Case Study of Dynamic Glucose Level Control in CHO Process Improves Product Quality" class="lazy-load w-main-feed-card-media object-cover babybear:max-h-[400px]" 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border-t-1 border-color-surface-border border-solid p-3 text-center text-md text-color-text-low-emphasis"> To view or add a comment, <a href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Fposts%2Fbioprocess-international_linking-mab-product-quality-profile-changes-activity-7262170663501639683--tbk&trk=public_post_feed-cta-banner-cta" target="" aria-label="To view or add a comment, sign in" data-tracking-control-name="public_post_feed-cta-banner-cta" data-tracking-will-navigate="true" class="feed-cta-banner__link link">sign in</a> </p> </article> <code id="is-mobile" style="display: none"></code> </div> </li> <li class="mb-1.5"> <div class="link-overlay relative"> <a aria-label="Post by Maurice Karrenbrock" class="absolute left-0 top-0 h-full w-full z-1 !border-0" data-tracking-control-name="link-overlay-public_post" href="https://www.linkedin.com/posts/maurice-karrenbrock_absolute-binding-free-energies-with-oneopes-activity-7243570085942988800-sglo" target="_self"></a> <article class="relative px-2 pb-0 bg-color-background-container container-lined pt-1.5 main-feed-activity-card related-posts__crosslink" data-activity-urn="urn:li:activity:7243570085942988800" data-featured-activity-urn="urn:li:activity:7243570085942988800" data-attributed-urn="urn:li:share:7243570085125120001">   <div class="flex"> <div class="base-main-feed-card__entity-lockup"> <div class="flex items-center font-sans mb-1" data-test-id="main-feed-activity-card__entity-lockup"> <a href="https://ch.linkedin.com/in/maurice-karrenbrock/en?trk=public_post_feed-actor-image" class="relative" data-tracking-control-name="public_post_feed-actor-image" data-tracking-will-navigate> <img class="inline-block relative rounded-[50%] w-6 h-6 " data-delayed-url="https://media.licdn.com/dms/image/v2/C5603AQFk4rk1vBFXxQ/profile-displayphoto-shrink_400_400/profile-displayphoto-shrink_400_400/0/1545574723597?e=2147483647&v=beta&t=QQoUGiBM0m5RIye7LRp8yMoq7MPiTkXkm0YyFEq5BV4" data-ghost-classes="bg-color-entity-ghost-background" data-ghost-url="https://static.licdn.com/aero-v1/sc/h/9c8pery4andzj6ohjkjp54ma2" alt="View profile for Maurice Karrenbrock, graphic">  </a> <div class="flex flex-col self-start min-w-0 ml-1 "> <div class="text-color-text "> <a class="text-sm link-styled no-underline leading-open" href="https://ch.linkedin.com/in/maurice-karrenbrock/en?trk=public_post_feed-actor-name" data-tracking-control-name="public_post_feed-actor-name" aria-label="View profile for Maurice Karrenbrock" data-tracking-will-navigate> Maurice Karrenbrock </a>  </div> <p class="!text-xs text-color-text-low-emphasis leading-[1.33333] m-0 truncate">  PhD in computational drug discovery CADD </p> <span class="!text-xs text-color-text-low-emphasis leading-[1.33333] flex"> <time class="flex-none"> 2mo  </time>  </span> </div>  </div> </div> <div class="ellipsis-menu absolute right-0 top-0 main-feed-activity-card__ellipsis-menu !top-auto !relative !mr-1" data-test-id="main-feed-activity-card__ellipsis-menu"> <div class="collapsible-dropdown flex items-center relative hyphens-auto"> <button class="ellipsis-menu__trigger collapsible-dropdown__button btn-md btn-tertiary cursor-pointer !py-[6px] !px-1 flex items-center rounded-[50%] " aria-expanded="false" aria-label="Open menu" data-tracking-control-name="public_post_ellipsis-menu-trigger" tabindex="0"> <icon class="ellipsis-menu__trigger-icon m-0 p-0 centered-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/671xosfpvk4c0kqtyl87hashi"></icon> </button> <ul class="collapsible-dropdown__list hidden container-raised absolute w-auto overflow-y-auto flex-col items-stretch z-1 bottom-auto top-[100%]" role="menu" tabindex="-1"> <li class="ellipsis-menu__item border-t-1 border-solid border-color-border-low-emphasis first-of-type:border-none flex"> <a href="/uas/login?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Fposts%2Fmaurice-karrenbrock_absolute-binding-free-energies-with-oneopes-activity-7243570085942988800-sglo&trk=public_post_ellipsis-menu-semaphore-sign-in-redirect&guestReportContentType=POST&_f=guest-reporting" data-tracking-control-name="public_post_ellipsis-menu-semaphore-sign-in-redirect" data-tracking-will-navigate data-item-type="semaphore" data-semaphore-content-type="POST" data-semaphore-content-urn="urn:li:activity:7243570085942988800" data-semaphore-tracking-prefix="public_post_ellipsis-menu-semaphore" data-is-logged-in="false" data-modal="semaphore__toggle" class="semaphore__toggle visited:text-color-text-secondary ellipsis-menu__semaphore ellipsis-menu__item-button flex items-center w-full p-1 cursor-pointer font-sans text-sm font-bold link-styled focus:link-styled link:no-underline active:bg-color-background-container-tint focus:bg-color-background-container-tint hover:bg-color-background-container-tint outline-offset-[-2px]">  <icon class="ellipsis-menu__item-icon text-color-text h-[24px] w-[24px] mr-1" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/iq0x9q37wj214o129ai1yjut"> </icon> Report this post </a>  </li>  </ul>  </div> </div> </div> <div class="attributed-text-segment-list__container relative mt-1 mb-1.5 babybear:mt-0 babybear:mb-0.5"> <p class="attributed-text-segment-list__content text-color-text !text-sm whitespace-pre-wrap break-words " dir="ltr" data-test-id="main-feed-activity-card__commentary">Our latest work has been published in the The Journal of Physical Chemistry Letters! <a class="link" href="https://lnkd.in/dX8c--5Y?trk=public_post-text" target="_self" rel="nofollow" data-tracking-control-name="public_post-text" data-tracking-will-navigate>https://lnkd.in/dX8c--5Y</a> Title: Absolute Binding Free Energies with OneOPES We have tackled the long-standing challenge of calculating absolute binding free energies (ABFEs) for protein-ligand systems. Our work introduces a transferable enhanced sampling strategy, OneOPES, utilizing simple geometric collective variables. Key Points: - Tested on BRD4 and Hsp90 with 17 chemically diverse ligands. - Achieved mean unsigned error within 1 kcal/mol of experimentally determined free energies. - No need to tailor collective variables for each system. - Accurately sampled different ligand binding modes and matched experimental structures from various initial configurations. Our findings suggest that OneOPES can effectively inform lead optimization in drug discovery and offer insights into protein-ligand binding and unbinding mechanisms. Check out the paper for more details! Reference: Absolute Binding Free Energies with OneOPES Maurice Karrenbrock, Alberto Borsatto, Valerio Rizzi, Dominykas Lukauskis, Simone Aureli, and Francesco Luigi Gervasio The Journal of Physical Chemistry Letters 0, 15 DOI: 10.1021/acs.jpclett.4c02352 <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fdrugdiscovery&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#DrugDiscovery</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fcomputationalchemistry&trk=public_post-text" target="_self" data-tracking-control-name="public_post-text" data-tracking-will-navigate>#ComputationalChemistry</a> <a class="link" href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww.linkedin.com%2Ffeed%2Fhashtag%2Fproteinligandbinding&trk=public_post-text" 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class="modal__overlay flex items-center bg-color-background-scrim justify-center fixed bottom-0 left-0 right-0 top-0 opacity-0 invisible pointer-events-none z-[1000] transition-[opacity] ease-[cubic-bezier(0.25,0.1,0.25,1.0)] duration-[0.17s] py-4 " aria-hidden="true"> <section aria-modal="true" role="dialog" aria-labelledby="public_post_contextual-sign-in-modal-header" tabindex="-1" class="max-h-full modal__wrapper overflow-auto p-0 bg-color-surface max-w-[1128px] min-h-[160px] relative scale-[0.25] shadow-sm shadow-color-border-faint transition-[transform] ease-[cubic-bezier(0.25,0.1,0.25,1.0)] duration-[0.33s] focus:outline-0 w-[1128px] mamabear:w-[744px] babybear:w-[360px] rounded-md"> <button class="modal__dismiss btn-tertiary h-[40px] w-[40px] p-0 rounded-full indent-0 contextual-sign-in-modal__modal-dismiss absolute right-0 m-[20px] cursor-pointer" aria-label="Dismiss" data-tracking-control-name="public_post_contextual-sign-in-modal_modal_dismiss"> <icon 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class="contextual-sign-in-modal__btn-container m-auto w-[320px] babybear:w-full">  <div class="w-full max-w-[400px] mx-auto"> <div class="google-auth-button">  <div class="google-auth-button__placeholder google-auth-button__placeholder--black-border" data-theme="outline" data-logo-alignment="center"></div>  </div> </div> <div class="sign-in-modal" data-impression-id="public_post_contextual-sign-in-modal_sign-in-modal"> <button class="sign-in-modal__outlet-btn cursor-pointer btn-md btn-primary" data-tracking-client-ingraph data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_outlet-button" data-modal="public_post_contextual-sign-in_sign-in-modal">  Sign in </button> <div class>  <div id="public_post_contextual-sign-in_sign-in-modal" class="modal modal--sign-in" data-outlet="public_post_contextual-sign-in_sign-in-modal">  <div class="modal__overlay flex items-center bg-color-background-scrim justify-center fixed bottom-0 left-0 right-0 top-0 opacity-0 invisible pointer-events-none z-[1000] transition-[opacity] ease-[cubic-bezier(0.25,0.1,0.25,1.0)] duration-[0.17s] py-4 " aria-hidden="true"> <section aria-modal="true" role="dialog" aria-labelledby="public_post_contextual-sign-in_sign-in-modal-modal-header" tabindex="-1" class="max-h-full modal__wrapper overflow-auto p-0 bg-color-surface max-w-[1128px] min-h-[160px] relative scale-[0.25] shadow-sm shadow-color-border-faint transition-[transform] ease-[cubic-bezier(0.25,0.1,0.25,1.0)] duration-[0.33s] focus:outline-0 w-[1128px] mamabear:w-[744px] babybear:w-[360px] rounded-md"> <button class="modal__dismiss btn-tertiary h-[40px] w-[40px] p-0 rounded-full indent-0 sign-in-modal__dismiss absolute right-0 cursor-pointer m-[20px]" aria-label="Dismiss" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_dismiss"> <icon class="sign-in-modal__dismiss-icon" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/gs508lg3t2o81tq7pmcgn6m2"></icon> </button> <div class="modal__main w-full"> <div class="sign-in-modal__screen flex flex-col py-4 w-[513px] babybear:w-full px-3"> <h2 class="sign-in-modal__header font-sans text-display-md text-color-text "> Welcome back </h2> <code id="i18n_sign_in_form_show_text" style="display: none"></code> <code id="i18n_sign_in_form_show_label" style="display: none"></code> <code id="i18n_sign_in_form_hide_text" style="display: none"></code> <code id="i18n_sign_in_form_hide_label" style="display: none"></code> <code id="i18n_username_error_empty" style="display: none"></code> <code id="i18n_username_error_too_long" style="display: none"></code> <code id="i18n_username_error_too_short" style="display: none"></code> <code id="i18n_password_error_empty" style="display: none"></code> <code id="i18n_password_error_too_short" style="display: none"></code> <code id="i18n_password_error_too_long" style="display: none"></code>  <form data-id="sign-in-form" action="https://www.linkedin.com/uas/login-submit" method="post" novalidate class="mt-1.5 mb-2"> <input name="loginCsrfParam" value="e71a1ca2-ccd1-4078-8a97-c25c516a6a98" type="hidden"> <div class="flex flex-col"> <div class="mt-1.5" data-js-module-id="guest-input"> <div class="flex flex-col"> <label class="input-label mb-1" for="public_post_contextual-sign-in_sign-in-modal_session_key"> Email or phone </label> <div class="text-input flex"> <input class="text-color-text font-sans text-md outline-0 bg-color-transparent grow" autocomplete="username" id="public_post_contextual-sign-in_sign-in-modal_session_key" name="session_key" required data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_sign-in-session-key" data-tracking-client-ingraph type="text"> </div> </div> <p class="input-helper mt-1.5" for="public_post_contextual-sign-in_sign-in-modal_session_key" role="alert" data-js-module-id="guest-input__message"></p> </div> <div class="mt-1.5" data-js-module-id="guest-input"> <div class="flex flex-col"> <label class="input-label mb-1" for="public_post_contextual-sign-in_sign-in-modal_session_password"> Password </label> <div class="text-input flex"> <input class="text-color-text font-sans text-md outline-0 bg-color-transparent grow" autocomplete="current-password" id="public_post_contextual-sign-in_sign-in-modal_session_password" name="session_password" required data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_sign-in-password" data-tracking-client-ingraph type="password"> <button aria-live="assertive" aria-relevant="text" data-id="sign-in-form__password-visibility-toggle" class="font-sans text-md font-bold text-color-action z-10 ml-[12px] hover:cursor-pointer" aria-label="Show your LinkedIn password" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_sign-in-password-visibility-toggle-btn" type="button">Show</button> </div> </div> <p class="input-helper mt-1.5" for="public_post_contextual-sign-in_sign-in-modal_session_password" role="alert" data-js-module-id="guest-input__message"></p> </div> <input name="session_redirect" value="https://www.linkedin.com/posts/jubilant-biosys_cro-crdmo-cdmo-activity-7261703281142300672-5BCY" type="hidden">  </div> <div data-id="sign-in-form__footer" class="flex justify-between sign-in-form__footer--full-width"> <a data-id="sign-in-form__forgot-password" class="font-sans text-md font-bold link leading-regular sign-in-form__forgot-password--full-width" href="https://www.linkedin.com/uas/request-password-reset?trk=public_post_contextual-sign-in-modal_sign-in-modal_forgot_password" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_forgot_password" data-tracking-will-navigate>Forgot password?</a>  <input name="trk" value="public_post_contextual-sign-in-modal_sign-in-modal_sign-in-submit" type="hidden"> <button class="btn-md btn-primary flex-shrink-0 cursor-pointer sign-in-form__submit-btn--full-width" data-id="sign-in-form__submit-btn" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_sign-in-submit-btn" data-tracking-client-ingraph data-tracking-litms type="submit"> Sign in </button> </div> <div class="sign-in-form__divider left-right-divider pt-2 pb-3"> <p class="sign-in-form__divider-text font-sans text-sm text-color-text px-2"> or </p> </div> </form> <div class="w-full max-w-[400px] mx-auto"> <div class="google-auth-button" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_google-auth-button" data-tracking-client-ingraph> <code id="isTermsAndConditionsSkipEnabledAuthButton" style="display: none"></code> <p class="linkedin-tc__text text-color-text-low-emphasis text-xs pb-2" data-impression-id="public_post_contextual-sign-in-modal_sign-in-modal__button-skip-tc-text"> By clicking Continue to join or sign in, you agree to LinkedIn’s <a href="/legal/user-agreement?trk=public_post_contextual-sign-in-modal_sign-in-modal_auth-button_user-agreement" target="_blank" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_auth-button_user-agreement" data-tracking-will-navigate="true">User Agreement</a>, <a href="/legal/privacy-policy?trk=public_post_contextual-sign-in-modal_sign-in-modal_auth-button_privacy-policy" target="_blank" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_auth-button_privacy-policy" data-tracking-will-navigate="true">Privacy Policy</a>, and <a href="/legal/cookie-policy?trk=public_post_contextual-sign-in-modal_sign-in-modal_auth-button_cookie-policy" target="_blank" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_auth-button_cookie-policy" data-tracking-will-navigate="true">Cookie Policy</a>. </p> <div class="google-auth-button__placeholder google-auth-button__placeholder--black-border" data-theme="outline" data-logo-alignment="center"></div>  </div> </div>  <p class="sign-in-modal__join-now m-auto font-sans text-md text-color-text mt-2"> New to LinkedIn? <a href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww%2Elinkedin%2Ecom%2Fposts%2Fjubilant-biosys_cro-crdmo-cdmo-activity-7261703281142300672-5BCY&trk=public_post_contextual-sign-in-modal_sign-in-modal_join-link" data-tracking-control-name="public_post_contextual-sign-in-modal_sign-in-modal_join-link" data-tracking-will-navigate="true" class="sign-in-modal__join-link">Join now</a> </p> </div> </div>  </section> </div> </div> </div> </div> <div class="contextual-sign-in-modal__divider left-right-divider"> <p class="contextual-sign-in-modal__divider-text font-sans text-sm text-color-text px-2"> or </p> </div> </div> <p class="contextual-sign-in-modal__join-now m-auto font-sans text-md text-color-text my-1"> New to LinkedIn? <a href="https://www.linkedin.com/signup/cold-join?session_redirect=https%3A%2F%2Fwww%2Elinkedin%2Ecom%2Fposts%2Fjubilant-biosys_cro-crdmo-cdmo-activity-7261703281142300672-5BCY&trk=public_post_contextual-sign-in-modal_join-link" data-tracking-control-name="public_post_contextual-sign-in-modal_join-link" data-tracking-will-navigate="true" class="contextual-sign-in-modal__join-link">Join now</a> </p> <p class="linkedin-tc__text text-color-text-low-emphasis text-xs pb-2 contextual-sign-in-modal__terms-and-conditions m-auto w-[320px] pt-2 babybear:w-full" data-impression-id="linkedin-tc__button-skip-tc-text"> By clicking Continue to join or sign in, you agree to LinkedIn’s <a href="/legal/user-agreement?trk=linkedin-tc_auth-button_user-agreement" target="_blank" data-tracking-control-name="linkedin-tc_auth-button_user-agreement" data-tracking-will-navigate="true">User Agreement</a>, <a href="/legal/privacy-policy?trk=linkedin-tc_auth-button_privacy-policy" target="_blank" data-tracking-control-name="linkedin-tc_auth-button_privacy-policy" data-tracking-will-navigate="true">Privacy Policy</a>, and <a href="/legal/cookie-policy?trk=linkedin-tc_auth-button_cookie-policy" target="_blank" data-tracking-control-name="linkedin-tc_auth-button_cookie-policy" data-tracking-will-navigate="true">Cookie Policy</a>. </p> </div> </div>  </section> </div> </div> </div> </div> <div class="cta-modal overflow-hidden container-raised z-10 fixed bottom-3 right-3 min-h-[56px] p-2 babybear:hidden windows-app-upsell windows-app-upsell--msft flex flex-col p-2 w-[359px] !bg-[#F1F8FA] opacity-90 backdrop-blur-[2px] z-1" data-impression-id="public_post_windows-app-upsell_cta-modal" role="dialog" aria-labelledby="cta-modal-header" aria-describedby="cta-modal-subheader"> <div class="windows-app-upsell__linkedin-title-container pt-[6px] mb-1.5 flex align-center"> <icon class="windows-app-upsell__linkedin-bug-icon block w-[21px] h-[21px]" data-svg-class-name="windows-app-upsell__linkedin-bug-icon-svg w-[21px] h-[21px]" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/euqjj7tf5wvr33frd3x1jj9s"></icon> <p class="windows-app-upsell__linkedin-title uppercase text-xs text-color-text-secondary leading-[21px] ml-1"> LinkedIn </p> </div> <p class="windows-app-upsell__title font-sans text-md text-color-text-accent-4-hover font-semibold leading-regular mb-1"> Never miss a beat on the app </p> <p class="windows-app-upsell__body font-sans text-sm text-color-text-secondary leading-regular"> Don’t have the app? Get it in the Microsoft Store. </p> <a class="windows-app-upsell__cta btn-sm btn-secondary-emphasis mt-2 mb-[6px] w-fit" href="ms-windows-store://pdp/?ProductId=9WZDNCRFJ4Q7&mode=mini&cid=guest_desktop_upsell_post2" data-tracking-client-ingraph data-tracking-control-name="public_post_windows-app-upsell_cta" data-tracking-will-navigate> Open the app </a> <button class="cta-modal__dismiss-btn absolute h-4 w-4 p-1 top-2 right-2 hover:cursor-pointer focus:outline focus:outline-2 focus:outline-color-action" data-tracking-control-name="public_post_windows-app-upsell_dismiss" aria-label="Dismiss"> <icon class="cta-modal__dismiss-icon block h-2 w-2 onload" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/adzjokfylbe8pvjr9h8iv96mw"></icon> </button> </div> <code id="activityUrn" style="display: none"></code> <div id="toasts" class="toasts fixed z-8 babybear:right-4 mamabear:right-4 papabear:min-h-[96px] invisible top:auto bottom-4 left-4 papabear:w-[400px] toasts--bottom" type="bottom"> <template id="toast-template"> <div class="toast container-raised flex toast--bottom transition ease-accelerate duration-xxslow " data-id="toast"> <div class="toast__message flex flex-1 babybear:items-center mamabear:items-center papabear:items-start py-2 px-1.5" data-id="toast__message" role="alert" tabindex="-1"> <div class="toast__message-content-container" data-id="toast__message-content-container"> <p class="toast__message-content font-sans text-sm opacity-90 inline babybear:self-center mamabear:self-center papabear:self-start" data-id="toast__message-content"></p> </div> </div> <button class="toast__dismiss-btn cursor-pointer babybear:self-center mamabear:self-center papabear:self-start pt-3 pb-2 papabear:py-2 pl-0.5 pr-0" data-id="toast__dismiss-btn" aria-label="Close"> <svg width="24" height="24" class="fill-color-icon"><path d="M13 4.32 9.31 8 13 11.69 11.69 13 8 9.31 4.31 13 3 11.69 6.69 8 3 4.31 4.31 3 8 6.69 11.68 3Z"></path></svg> </button> </div> </template> <template id="toast-icon-caution"> <icon class="text-color-icon-caution toast__icon w-3 h-3 shrink-0 mr-2" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/u6kgm8vi5s4rhtbgmjlphlp6"></icon> </template> <template id="toast-icon-error"> <icon class="text-color-icon-negative toast__icon w-3 h-3 shrink-0 mr-2" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/2ffvlzyh9wb65459t9va8w2ph"></icon> </template> <template id="toast-icon-gdpr"> <icon class="text-color-icon-neutral toast__icon w-3 h-3 shrink-0 mr-2" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/a0d85elrpgg38lskvq1kvzb3"></icon> </template> <template id="toast-icon-notify"> <icon class="text-color-icon-neutral toast__icon w-3 h-3 shrink-0 mr-2" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/de23f5me7dfm17unsj9up4vga"></icon> </template> <template id="toast-icon-success"> <icon class="text-color-icon-positive toast__icon w-3 h-3 shrink-0 mr-2" data-delayed-url="https://static.licdn.com/aero-v1/sc/h/c44ryoszao52cyd0y87z7s0uf"></icon> </template> <template id="toast-cta"> <a class="toast__cta cta-link font-medium ml-0.5 text-sm text-inherit inline" target="_blank"></a> </template> </div> <script src="https://static.licdn.com/aero-v1/sc/h/4kdl05tfo7lc1e6o63oput2ah" async></script>  <script src="https://static.licdn.com/aero-v1/sc/h/6m1b8t00vuxmc30ew42uoizb7" async defer></script> <script data-delayed-url="https://static.licdn.com/aero-v1/sc/h/81wy0f4hfrhoilx9eqdwg202z" data-module-id="media-player"></script>  </body> </html>

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Jubilant Biosys Limited on LinkedIn: #cro #crdmo #cdmo #computationalchemistry #drugdesign #pharmainnovation…