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class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Properties and reactions subsection</span> </button> <ul id="toc-Properties_and_reactions-sublist" class="vector-toc-list"> <li id="toc-Structure" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Structure"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.1</span> <span>Structure</span> </div> </a> <ul id="toc-Structure-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Society_and_culture" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Society_and_culture"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Society and culture</span> </div> </a> <button aria-controls="toc-Society_and_culture-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Society and culture subsection</span> </button> <ul id="toc-Society_and_culture-sublist" class="vector-toc-list"> <li id="toc-Environmental_effects" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Environmental_effects"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.1</span> <span>Environmental effects</span> </div> </a> <ul id="toc-Environmental_effects-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Arsenic_poisoning_in_literature_and_society" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Arsenic_poisoning_in_literature_and_society"> <div class="vector-toc-text"> <span class="vector-toc-numb">5.2</span> <span>Arsenic poisoning in literature and society</span> </div> </a> <ul id="toc-Arsenic_poisoning_in_literature_and_society-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Arsenic trioxide</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 47 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-47" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">47 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A3%D9%83%D8%B3%D9%8A%D8%AF_%D8%A7%D9%84%D8%B2%D8%B1%D9%86%D9%8A%D8%AE_%D8%A7%D9%84%D8%AB%D9%84%D8%A7%D8%AB%D9%8A" title="أكسيد الزرنيخ الثلاثي – Arabic" lang="ar" hreflang="ar" data-title="أكسيد الزرنيخ الثلاثي" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%A2%D8%B1%D8%B3%D9%86%DB%8C%DA%A9_%D8%AA%D8%B1%DB%8C%D8%A7%D9%88%DA%A9%D8%B3%DB%8C%D8%AF" title="آرسنیک تریاوکسید – South Azerbaijani" lang="azb" hreflang="azb" data-title="آرسنیک تریاوکسید" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-zh-min-nan mw-list-item"><a href="https://zh-min-nan.wikipedia.org/wiki/Sam-sng-ho%C3%A0_phi-s%C3%B2%CD%98" title="Sam-sng-hoà phi-sò͘ – Minnan" lang="nan" hreflang="nan" data-title="Sam-sng-hoà phi-sò͘" data-language-autonym="閩南語 / Bân-lâm-gú" data-language-local-name="Minnan" class="interlanguage-link-target"><span>閩南語 / Bân-lâm-gú</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%90%D1%80%D1%81%D0%B5%D0%BD%D0%B8%D0%BA" title="Арсеник – Bulgarian" lang="bg" hreflang="bg" data-title="Арсеник" data-language-autonym="Български" data-language-local-name="Bulgarian" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/%C3%92xid_d%27ars%C3%A8nic(III)" title="Òxid d'arsènic(III) – Catalan" lang="ca" hreflang="ca" data-title="Òxid d'arsènic(III)" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Oxid_arsenit%C3%BD" title="Oxid arsenitý – Czech" lang="cs" hreflang="cs" data-title="Oxid arsenitý" data-language-autonym="Čeština" data-language-local-name="Czech" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Arsenik" title="Arsenik – Danish" lang="da" hreflang="da" data-title="Arsenik" data-language-autonym="Dansk" data-language-local-name="Danish" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Arsen(III)-oxid" title="Arsen(III)-oxid – German" lang="de" hreflang="de" data-title="Arsen(III)-oxid" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Diarseentrioksiid" title="Diarseentrioksiid – Estonian" lang="et" hreflang="et" data-title="Diarseentrioksiid" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A4%CF%81%CE%B9%CE%BF%CE%BE%CE%B5%CE%AF%CE%B4%CE%B9%CE%BF_%CF%84%CE%BF%CF%85_%CE%B1%CF%81%CF%83%CE%B5%CE%BD%CE%B9%CE%BA%CE%BF%CF%8D" title="Τριοξείδιο του αρσενικού – Greek" lang="el" hreflang="el" data-title="Τριοξείδιο του αρσενικού" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/%C3%93xido_de_ars%C3%A9nico_(III)" title="Óxido de arsénico (III) – Spanish" lang="es" hreflang="es" data-title="Óxido de arsénico (III)" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Arseniko" title="Arseniko – Esperanto" lang="eo" hreflang="eo" data-title="Arseniko" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A2%D8%B1%D8%B3%D9%86%DB%8C%DA%A9_%D8%AA%D8%B1%DB%8C%E2%80%8C%D8%A7%DA%A9%D8%B3%DB%8C%D8%AF" title="آرسنیک تری‌اکسید – Persian" lang="fa" hreflang="fa" data-title="آرسنیک تری‌اکسید" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Anhydride_ars%C3%A9nieux" title="Anhydride arsénieux – French" lang="fr" hreflang="fr" data-title="Anhydride arsénieux" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%82%BC%EC%82%B0%ED%99%94_%EC%9D%B4%EB%B9%84%EC%86%8C" title="삼산화 이비소 – Korean" lang="ko" hreflang="ko" data-title="삼산화 이비소" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%86%E0%A4%B0%E0%A5%8D%E0%A4%B8%E0%A5%87%E0%A4%A8%E0%A4%BF%E0%A4%95_%E0%A4%9F%E0%A5%8D%E0%A4%B0%E0%A4%BE%E0%A4%87%E0%A4%91%E0%A4%95%E0%A5%8D%E0%A4%B8%E0%A4%BE%E0%A4%87%E0%A4%A1" title="आर्सेनिक ट्राइऑक्साइड – Hindi" lang="hi" hreflang="hi" data-title="आर्सेनिक ट्राइऑक्साइड" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Arsen_trioksida" title="Arsen trioksida – Indonesian" lang="id" hreflang="id" data-title="Arsen trioksida" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Ossido_arsenioso" title="Ossido arsenioso – Italian" lang="it" hreflang="it" data-title="Ossido arsenioso" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%90%D7%A8%D7%A1%D7%A0%D7%99%D7%A7_%D7%98%D7%A8%D7%99%D7%90%D7%95%D7%A7%D7%A1%D7%99%D7%93" title="ארסניק טריאוקסיד – Hebrew" lang="he" hreflang="he" data-title="ארסניק טריאוקסיד" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Arz%C3%A9n-trioxid" title="Arzén-trioxid – Hungarian" lang="hu" hreflang="hu" data-title="Arzén-trioxid" data-language-autonym="Magyar" data-language-local-name="Hungarian" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/A%D1%80%D1%81%D0%B5%D0%BD_%D1%82%D1%80%D0%B8%D0%BE%D0%BA%D1%81%D0%B8%D0%B4" title="Aрсен триоксид – Macedonian" lang="mk" hreflang="mk" data-title="Aрсен триоксид" data-language-autonym="Македонски" data-language-local-name="Macedonian" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%86%E0%B4%B4%E0%B5%8D%E0%B4%B8%E0%B4%A8%E0%B4%BF%E0%B4%95%E0%B5%8D_%E0%B4%9F%E0%B5%8D%E0%B4%B0%E0%B4%AF%E0%B5%8B%E0%B4%95%E0%B5%8D%E0%B4%B8%E0%B5%88%E0%B4%A1%E0%B5%8D" title="ആഴ്സനിക് ട്രയോക്സൈഡ് – Malayalam" lang="ml" hreflang="ml" data-title="ആഴ്സനിക് ട്രയോക്സൈഡ്" data-language-autonym="മലയാളം" data-language-local-name="Malayalam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-cdo mw-list-item"><a href="https://cdo.wikipedia.org/wiki/P%C4%AD-s%C5%8Fng" title="Pĭ-sŏng – Mindong" lang="cdo" hreflang="cdo" data-title="Pĭ-sŏng" data-language-autonym="閩東語 / Mìng-dĕ̤ng-ngṳ̄" data-language-local-name="Mindong" class="interlanguage-link-target"><span>閩東語 / Mìng-dĕ̤ng-ngṳ̄</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Arseen(III)oxide" title="Arseen(III)oxide – Dutch" lang="nl" hreflang="nl" data-title="Arseen(III)oxide" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E4%B8%89%E9%85%B8%E5%8C%96%E4%BA%8C%E3%83%92%E7%B4%A0" title="三酸化二ヒ素 – Japanese" lang="ja" hreflang="ja" data-title="三酸化二ヒ素" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Arsenikk" title="Arsenikk – Norwegian Bokmål" lang="nb" hreflang="nb" data-title="Arsenikk" data-language-autonym="Norsk bokmål" data-language-local-name="Norwegian Bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Arsenikk" title="Arsenikk – Norwegian Nynorsk" lang="nn" hreflang="nn" data-title="Arsenikk" data-language-autonym="Norsk nynorsk" data-language-local-name="Norwegian Nynorsk" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%86%E0%AC%B0%E0%AD%8D%E0%AC%B8%E0%AD%87%E0%AC%A8%E0%AC%BF%E0%AC%95_%E0%AC%9F%E0%AD%8D%E0%AC%B0%E0%AC%BE%E0%AC%87%E0%AC%85%E0%AC%95%E0%AD%8D%E0%AC%B8%E0%AC%BE%E0%AC%87%E0%AC%A1" title="ଆର୍ସେନିକ ଟ୍ରାଇଅକ୍ସାଇଡ – Odia" lang="or" hreflang="or" data-title="ଆର୍ସେନିକ ଟ୍ରାଇଅକ୍ସାଇଡ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="Odia" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Tritlenek_diarsenu" title="Tritlenek diarsenu – Polish" lang="pl" hreflang="pl" data-title="Tritlenek diarsenu" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Tri%C3%B3xido_de_ars%C3%AAnio" title="Trióxido de arsênio – Portuguese" lang="pt" hreflang="pt" data-title="Trióxido de arsênio" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Trioxid_de_arsen" title="Trioxid de arsen – Romanian" lang="ro" hreflang="ro" data-title="Trioxid de arsen" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9E%D0%BA%D1%81%D0%B8%D0%B4_%D0%BC%D1%8B%D1%88%D1%8C%D1%8F%D0%BA%D0%B0(III)" title="Оксид мышьяка(III) – Russian" lang="ru" hreflang="ru" data-title="Оксид мышьяка(III)" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Arsenic_trioxide" title="Arsenic trioxide – Simple English" lang="en-simple" hreflang="en-simple" data-title="Arsenic trioxide" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Oxid_arzenit%C3%BD" title="Oxid arzenitý – Slovak" lang="sk" hreflang="sk" data-title="Oxid arzenitý" data-language-autonym="Slovenčina" data-language-local-name="Slovak" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Arzenov_trioksid" title="Arzenov trioksid – Slovenian" lang="sl" hreflang="sl" data-title="Arzenov trioksid" data-language-autonym="Slovenščina" data-language-local-name="Slovenian" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Arsenik_trioksid" title="Arsenik trioksid – Serbian" lang="sr" hreflang="sr" data-title="Arsenik trioksid" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Arsenik_trioksid" title="Arsenik trioksid – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Arsenik trioksid" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Arseenitrioksidi" title="Arseenitrioksidi – Finnish" lang="fi" hreflang="fi" data-title="Arseenitrioksidi" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Arseniktrioxid" title="Arseniktrioxid – Swedish" lang="sv" hreflang="sv" data-title="Arseniktrioxid" data-language-autonym="Svenska" data-language-local-name="Swedish" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%86%E0%AE%B0%E0%AF%8D%E0%AE%9A%E0%AE%A9%E0%AE%BF%E0%AE%95%E0%AF%8D_%E0%AE%AE%E0%AF%82%E0%AE%B5%E0%AE%BE%E0%AE%95%E0%AF%8D%E0%AE%9A%E0%AF%88%E0%AE%9F%E0%AF%81" title="ஆர்சனிக் மூவாக்சைடு – Tamil" lang="ta" hreflang="ta" data-title="ஆர்சனிக் மூவாக்சைடு" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%AD%E0%B8%B2%E0%B8%A3%E0%B9%8C%E0%B9%80%E0%B8%8B%E0%B8%99%E0%B8%B4%E0%B8%81%E0%B9%84%E0%B8%95%E0%B8%A3%E0%B8%AD%E0%B8%AD%E0%B8%81%E0%B9%84%E0%B8%8B%E0%B8%94%E0%B9%8C" title="อาร์เซนิกไตรออกไซด์ – Thai" lang="th" hreflang="th" data-title="อาร์เซนิกไตรออกไซด์" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Arsenik_trioksit" title="Arsenik trioksit – Turkish" lang="tr" hreflang="tr" data-title="Arsenik trioksit" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9E%D0%BA%D1%81%D0%B8%D0%B4_%D0%B0%D1%80%D1%81%D0%B5%D0%BD%D1%83(III)" title="Оксид арсену(III) – Ukrainian" lang="uk" hreflang="uk" data-title="Оксид арсену(III)" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Diarsenic_trioxide" title="Diarsenic trioxide – Vietnamese" lang="vi" hreflang="vi" data-title="Diarsenic trioxide" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh-classical mw-list-item"><a href="https://zh-classical.wikipedia.org/wiki/%E7%A0%92%E9%9C%9C" title="砒霜 – Literary Chinese" lang="lzh" hreflang="lzh" data-title="砒霜" data-language-autonym="文言" data-language-local-name="Literary Chinese" class="interlanguage-link-target"><span>文言</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E7%A0%92%E9%9C%9C" title="砒霜 – Cantonese" lang="yue" 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.infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox" style="border-spacing:2px;"><caption class="infobox-title"><span title="International nonproprietary name (INN): Arsenic trioxide">Arsenic trioxide</span></caption><tbody><tr><td colspan="2" class="infobox-image notheme" style="background-color: #f8f9fa;"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Arsenic_trioxide.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Arsenic_trioxide.jpg/220px-Arsenic_trioxide.jpg" decoding="async" width="220" height="173" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Arsenic_trioxide.jpg/330px-Arsenic_trioxide.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Arsenic_trioxide.jpg/440px-Arsenic_trioxide.jpg 2x" data-file-width="542" data-file-height="425" /></a></span></td></tr><tr><td colspan="2" class="infobox-image notheme" style="background-color: #f8f9fa;"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:As4O6-molecule-from-arsenolite-xtal-3D-balls.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cf/As4O6-molecule-from-arsenolite-xtal-3D-balls.png/220px-As4O6-molecule-from-arsenolite-xtal-3D-balls.png" decoding="async" width="220" height="236" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/cf/As4O6-molecule-from-arsenolite-xtal-3D-balls.png/330px-As4O6-molecule-from-arsenolite-xtal-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/cf/As4O6-molecule-from-arsenolite-xtal-3D-balls.png/440px-As4O6-molecule-from-arsenolite-xtal-3D-balls.png 2x" data-file-width="1026" data-file-height="1100" /></a></span><div class="infobox-caption">Arsenic trioxide <style data-mw-deduplicate="TemplateStyles:r981673959">.mw-parser-output .legend{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .legend-color{display:inline-block;min-width:1.25em;height:1.25em;line-height:1.25;margin:1px 0;text-align:center;border:1px solid black;background-color:transparent;color:black}.mw-parser-output .legend-text{}</style><span class="legend-color mw-no-invert" style="background-color:#bd80e3; color:black;border:1px solid darkgray;"> </span> <a href="/wiki/Arsenic" title="Arsenic">As</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r981673959"><span class="legend-color mw-no-invert" style="background-color:#ee2010; color:black;border:1px solid darkgray;"> </span> <a href="/wiki/Oxide" title="Oxide">O</a></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Clinical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">Pronunciation</th><td class="infobox-data">AR se nik tri OKS id </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_nomenclature#Trade_names" title="Drug nomenclature">Trade names</a></th><td class="infobox-data">Trisenox, others</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">Other names</th><td class="infobox-data">Arsenic(III) oxide,<br />Arsenic <a href="/wiki/Sesquioxide" title="Sesquioxide">sesquioxide</a>,<br />Arseneous oxide,<br />Ratsbane,<br />Arseneous anhydride,<br />White arsenic,<br />Aqua Tofani<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/American_Society_of_Health-System_Pharmacists" title="American Society of Health-System Pharmacists">AHFS</a>/<a href="/wiki/Drugs.com" title="Drugs.com">Drugs.com</a></th><td class="infobox-data"><span title="www.drugs.com"><a rel="nofollow" class="external text" href="https://www.drugs.com/monograph/arsenic-trioxide.html">Monograph</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th><td class="infobox-data"><span title="medlineplus.gov"><a rel="nofollow" class="external text" href="https://medlineplus.gov/druginfo/meds/a608017.html">a608017</a></span></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">License data</a></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"> <ul><li><small><abbr class="country-name" title="United States">US</abbr></small> <a href="/wiki/DailyMed" title="DailyMed">DailyMed</a>: <span title="dailymed.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Arsenic+trioxide">Arsenic trioxide</a></span></li></ul></div> </td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Pregnancy_category" title="Pregnancy category">Pregnancy<br />category</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> X (High risk)</li> <li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Route_of_administration" title="Route of administration">Routes of<br />administration</a></th><td class="infobox-data"><a href="/wiki/Intravenous" class="mw-redirect" title="Intravenous">Intravenous</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Drug_class" title="Drug class">Drug class</a></th><td class="infobox-data"><a href="/wiki/Antineoplastic_agent" class="mw-redirect" title="Antineoplastic agent">Antineoplastic agent</a></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Anatomical_Therapeutic_Chemical_Classification_System" title="Anatomical Therapeutic Chemical Classification System">ATC code</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><a href="/wiki/ATC_code_L01" title="ATC code L01">L01XX27</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=L01XX27">WHO</a></span>) </li></ul></div></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Legal status</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"> <ul><li><small><abbr class="country-name" title="Australia">AU</abbr>:</small> <a href="/wiki/Standard_for_the_Uniform_Scheduling_of_Medicines_and_Poisons#Schedule_4" title="Standard for the Uniform Scheduling of Medicines and Poisons">S4</a> (Prescription only)</li> <li><small><abbr class="country-name" title="United States">US</abbr>:</small> <a href="/wiki/Prescription_drug" title="Prescription drug">℞-only</a><sup id="cite_ref-Trisenox_FDA_label_2-0" class="reference"><a href="#cite_note-Trisenox_FDA_label-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></li> <li><small><abbr class="country-name" title="European Union">EU</abbr>:</small> Rx-only<sup id="cite_ref-Trisenox_EPAR_3-0" class="reference"><a href="#cite_note-Trisenox_EPAR-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li></ul></div> </td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd"><a href="/wiki/Pharmacokinetics" title="Pharmacokinetics">Pharmacokinetic</a> data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Plasma_protein_binding" title="Plasma protein binding">Protein binding</a></th><td class="infobox-data">75%</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Excretion" title="Excretion">Excretion</a></th><td class="infobox-data">Urine</td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Identifiers</th></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/IUPAC_nomenclature_of_chemistry" title="IUPAC nomenclature of chemistry">IUPAC name</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all; text-align:left; padding-left:1.5em; text-indent:-1.5em;"><li style="line-height: inherit; margin: 0"><div style="font-size: 97%;">Diarsenic trioxide</div></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=1327-53-3">1327-53-3</a></span> <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/PubChem#CID" title="PubChem">PubChem</a> <span style="font-weight:normal"><abbr title="Compound ID">CID</abbr></span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/261004">261004</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB01169">DB01169</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.452539.html">452539</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/S7V92P67HO">S7V92P67HO</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/C13619">C13619</a></span></li><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D02106">D02106</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/ChEMBL1200978">ChEMBL1200978</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID0020103">DTXSID0020103</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q7739#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.014.075">100.014.075</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q7739#P2566" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></td></tr><tr><th colspan="2" class="infobox-header" style="background:#ddd">Chemical and physical data</th></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Chemical_formula" title="Chemical formula">Formula</a></th><td class="infobox-data"><span title="Arsenic">As</span><sub>2</sub><span title="Oxygen">O</span><sub>3</sub></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a></th><td class="infobox-data"><span class="nowrap"><span data-sort-value="7002197840000000000♠"></span>197.840</span> g·mol<sup>−1</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</th><td class="infobox-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=O1%5BAs%5D3O%5BAs%5D2O%5BAs%5D%28O3%29O%5BAs%5D1O2">Interactive image</a></span></li></ul></div></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Density" title="Density">Density</a></th><td class="infobox-data">3.74 g/cm<sup>3</sup></td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Melting_point" title="Melting point">Melting point</a></th><td class="infobox-data">312.2 °C (594.0 °F)</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Boiling_point" title="Boiling point">Boiling point</a></th><td class="infobox-data">465 °C (869 °F)</td></tr><tr><th scope="row" class="infobox-label" style="line-height:1.2em;"><a href="/wiki/Aqueous_solution" title="Aqueous solution">Solubility in water</a></th><td class="infobox-data">20 g/L (25 °C)<br /> (see text)</td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">O1[As]3O[As]2O[As](O3)O[As]1O2</div></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">InChI=1S/As2O3/c3-1-4-2(3)5-1<br /><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></div></li><li style="line-height: inherit; margin: 0"><div style="word-wrap:break-word; text-indent:-1.5em; text-align:left; padding-left:1.5em; font-size:97%; line-height:120%;">Key:GOLCXWYRSKYTSP-UHFFFAOYSA-N</div></li></ul> </div></td></tr></tbody></table> <style data-mw-deduplicate="TemplateStyles:r1084375498">.mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}</style> <table class="infobox ib-chembox"> <caption>Arsenic trioxide </caption> <tbody><tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Identifiers </th></tr> <tr> <td><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a> </td> <td><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.014.075">100.014.075</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q7739#P2566" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span> </td></tr> <tr> <td><a href="/wiki/European_Community_number" title="European Community number"><span title="European Community number (chemical identifier)">EC Number</span></a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li>215-481-4</li></ul></div> </td></tr> <tr> <td><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<abbr title="U.S. Environmental Protection Agency">EPA</abbr>)</span></div> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/chemical/details/DTXSID0020103">DTXSID0020103</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q7739#P3117" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Hazards </th></tr> <tr> <td colspan="2" style="text-align:left; background-color:#eaeaea;"><a href="/wiki/Globally_Harmonized_System_of_Classification_and_Labelling_of_Chemicals" title="Globally Harmonized System of Classification and Labelling of Chemicals"><b>GHS</b> labelling</a>:<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td style="padding-left:1em;"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/GHS_hazard_pictograms" title="GHS hazard pictograms">Pictograms</a></div> </td> <td><span typeof="mw:File"><a href="/wiki/File:GHS-pictogram-acid.svg" class="mw-file-description" title="GHS05: Corrosive"><img alt="GHS05: Corrosive" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a1/GHS-pictogram-acid.svg/50px-GHS-pictogram-acid.svg.png" decoding="async" width="50" height="50" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a1/GHS-pictogram-acid.svg/75px-GHS-pictogram-acid.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a1/GHS-pictogram-acid.svg/100px-GHS-pictogram-acid.svg.png 2x" data-file-width="724" data-file-height="724" /></a></span> <span typeof="mw:File"><a href="/wiki/File:GHS-pictogram-skull.svg" class="mw-file-description" title="GHS06: Toxic"><img alt="GHS06: Toxic" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/58/GHS-pictogram-skull.svg/50px-GHS-pictogram-skull.svg.png" decoding="async" width="50" height="50" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/58/GHS-pictogram-skull.svg/75px-GHS-pictogram-skull.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/58/GHS-pictogram-skull.svg/100px-GHS-pictogram-skull.svg.png 2x" data-file-width="724" data-file-height="724" /></a></span> <span typeof="mw:File"><a href="/wiki/File:GHS-pictogram-silhouette.svg" class="mw-file-description" title="GHS08: Health hazard"><img alt="GHS08: Health hazard" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/21/GHS-pictogram-silhouette.svg/50px-GHS-pictogram-silhouette.svg.png" decoding="async" width="50" height="50" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/21/GHS-pictogram-silhouette.svg/75px-GHS-pictogram-silhouette.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/21/GHS-pictogram-silhouette.svg/100px-GHS-pictogram-silhouette.svg.png 2x" data-file-width="724" data-file-height="724" /></a></span> <span typeof="mw:File"><a href="/wiki/File:GHS-pictogram-pollu.svg" class="mw-file-description" title="GHS09: Environmental hazard"><img alt="GHS09: Environmental hazard" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b9/GHS-pictogram-pollu.svg/50px-GHS-pictogram-pollu.svg.png" decoding="async" width="50" height="50" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b9/GHS-pictogram-pollu.svg/75px-GHS-pictogram-pollu.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b9/GHS-pictogram-pollu.svg/100px-GHS-pictogram-pollu.svg.png 2x" data-file-width="724" data-file-height="724" /></a></span> </td></tr> <tr> <td style="padding-left:1em;"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/Globally_Harmonized_System_of_Classification_and_Labelling_of_Chemicals#Signal_word" title="Globally Harmonized System of Classification and Labelling of Chemicals">Signal word</a></div> </td> <td><b>Danger</b> </td></tr> <tr> <td style="padding-left:1em;"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/GHS_hazard_statements" title="GHS hazard statements">Hazard statements</a></div> </td> <td><abbr class="abbr" title="H300: Fatal if swallowed">H300</abbr>, <abbr class="abbr" title="H314: Causes severe skin burns and eye damage">H314</abbr>, <abbr class="abbr" title="H350: May cause cancer">H350</abbr>, <abbr class="abbr" title="H410: Very toxic to aquatic life with long lasting effects">H410</abbr> </td></tr> <tr> <td style="padding-left:1em;"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/GHS_precautionary_statements" title="GHS precautionary statements">Precautionary statements</a></div> </td> <td><abbr class="abbr" title="P201: Obtain special instructions before use.">P201</abbr>, <abbr class="abbr" title="P202: Do not handle until all safety precautions have been read and understood.">P202</abbr>, <abbr class="abbr" title="P260: Do not breathe dust/fume/gas/mist/vapours/spray.">P260</abbr>, <abbr class="abbr" title="P264: Wash ... thoroughly after handling.">P264</abbr>, <abbr class="abbr" title="P270: Do not eat, drink or smoke when using this product.">P270</abbr>, <abbr class="abbr" title="P273: Avoid release to the environment.">P273</abbr>, <abbr class="abbr" title="P280: Wear protective gloves/protective clothing/eye protection/face protection.">P280</abbr>, <abbr class="abbr" title="P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.">P301+P330+P331</abbr>, <abbr class="abbr" title="P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water [or shower].">P303+P361+P353</abbr>, <abbr class="abbr" title="P304+P340+P310: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician.">P304+P340+P310</abbr>, <abbr class="abbr" title="P305+P351+P338+P310: IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.">P305+P351+P338+P310</abbr>, <abbr class="abbr" title="P308+P313: IF exposed or concerned: Get medical advice/attention.">P308+P313</abbr>, <abbr class="abbr" title="P363: Wash contaminated clothing before reuse.">P363</abbr>, <abbr class="abbr" title="P391: Collect spillage.">P391</abbr>, <abbr class="abbr" title="P405: Store locked up.">P405</abbr>, <abbr class="abbr" title="P501: Dispose of contents/container to ...">P501</abbr> </td></tr> <tr> <td><a href="/wiki/Safety_data_sheet" title="Safety data sheet">Safety data sheet</a> (SDS) </td> <td><a rel="nofollow" class="external text" href="https://www.americanelements.com/printpdf/arsenic-iii-oxide-1327-53-3/sds">american elements SDS</a> </td></tr> </tbody></table><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Chemical compound</div> <p><b>Arsenic trioxide</b> is an <a href="/wiki/Inorganic_compound" title="Inorganic compound">inorganic compound</a> with the <a href="/wiki/Chemical_formula" title="Chemical formula">formula</a> <b><span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span></b>.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> As an industrial chemical, its major uses include the manufacture of <a href="/wiki/Wood_preservative" class="mw-redirect" title="Wood preservative">wood preservatives</a>, <a href="/wiki/Pesticide" title="Pesticide">pesticides</a>, and <a href="/wiki/Glass_manufacturing" class="mw-redirect" title="Glass manufacturing">glass</a>.<sup id="cite_ref-Land2012_6-0" class="reference"><a href="#cite_note-Land2012-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> It is sold under the brand name <b>Trisenox</b> among others<sup id="cite_ref-Trisenox_FDA_label_2-1" class="reference"><a href="#cite_note-Trisenox_FDA_label-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Trisenox_EPAR_3-1" class="reference"><a href="#cite_note-Trisenox_EPAR-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> when used as a medication to treat a type of <a href="/wiki/Cancer" title="Cancer">cancer</a> known as <a href="/wiki/Acute_promyelocytic_leukemia" title="Acute promyelocytic leukemia">acute promyelocytic leukemia</a>.<sup id="cite_ref-AHFS2019_7-0" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> For this use it is given by <a href="/wiki/Injection_into_a_vein" class="mw-redirect" title="Injection into a vein">injection into a vein</a>.<sup id="cite_ref-AHFS2019_7-1" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Common side effects include vomiting, diarrhea, swelling, shortness of breath, and headaches.<sup id="cite_ref-AHFS2019_7-2" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Severe side effects may include <a href="/wiki/APL_differentiation_syndrome" class="mw-redirect" title="APL differentiation syndrome">APL differentiation syndrome</a> and heart problems.<sup id="cite_ref-AHFS2019_7-3" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Use during pregnancy or breastfeeding may harm the baby.<sup id="cite_ref-BNF76_8-0" class="reference"><a href="#cite_note-BNF76-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Its mechanism in treating cancer is not entirely clear.<sup id="cite_ref-AHFS2019_7-4" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Arsenic trioxide was approved for medical use in the United States in 2000.<sup id="cite_ref-AHFS2019_7-5" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> It is on the <a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">World Health Organization's List of Essential Medicines</a>.<sup id="cite_ref-WHO23rd_10-0" class="reference"><a href="#cite_note-WHO23rd-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Approximately 50,000 <a href="/wiki/Tonne" title="Tonne">tonnes</a> are produced a year.<sup id="cite_ref-Ullmann_11-0" class="reference"><a href="#cite_note-Ullmann-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Due to its toxicity, a number of countries have regulations around its manufacture and sale.<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Uses">Uses</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=1" title="Edit section: Uses"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Medical">Medical</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=2" title="Edit section: Medical"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Medical_use_of_arsenic_trioxide" title="Medical use of arsenic trioxide">Medical use of arsenic trioxide</a></div> <p>Arsenic trioxide is <a href="/wiki/Indicated" class="mw-redirect" title="Indicated">indicated</a> in combination with <a href="/wiki/Tretinoin" title="Tretinoin">tretinoin</a> for treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia whose acute promyelocytic leukemia is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression; and for induction of remission and consolidation in patients with acute promyelocytic leukemia who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose acute promyelocytic leukemia is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression.<sup id="cite_ref-Trisenox_FDA_label_2-2" class="reference"><a href="#cite_note-Trisenox_FDA_label-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Trisenox_EPAR_3-2" class="reference"><a href="#cite_note-Trisenox_EPAR-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Drug_Approval_Package:_Trisenox_13-0" class="reference"><a href="#cite_note-Drug_Approval_Package:_Trisenox-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> </p><p>Arsenic trioxide is used to treat a type of cancer known as <a href="/wiki/Acute_promyelocytic_leukemia" title="Acute promyelocytic leukemia">acute promyelocytic leukemia</a> (APL).<sup id="cite_ref-AHFS2019_7-6" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> It may be used both in cases that are unresponsive to other agents, such as <a href="/wiki/Tretinoin" title="Tretinoin">all-trans retinoic acid</a> (ATRA) or as part of the initial treatment of newly diagnosed cases.<sup id="cite_ref-AHFS2019_7-7" class="reference"><a href="#cite_note-AHFS2019-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> This initial treatment may include combination therapy of arsenic trioxide with all-trans retinoic acid (ATRA).<sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p><p>Effectiveness appears similar to <a href="/wiki/Realgar/Indigo_naturalis" title="Realgar/Indigo naturalis">Realgar/Indigo naturalis</a>, which can be taken by mouth and is less expensive but is less available.<sup id="cite_ref-WHO2019Apply_15-0" class="reference"><a href="#cite_note-WHO2019Apply-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> It works by encouraging the <a href="/wiki/Proteosome" class="mw-redirect" title="Proteosome">proteosome</a> breakdown of <a href="/wiki/Retinoic_acid_receptor_alpha" title="Retinoic acid receptor alpha">retinoic acid receptor alpha</a>, by moving the protein on to the <a href="/wiki/Nuclear_matrix" title="Nuclear matrix">nuclear matrix</a> and increasing <a href="/wiki/Ubiquitination" class="mw-redirect" title="Ubiquitination">ubiquitination</a>.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p><p>In the 1970s, Chinese researcher <a href="/wiki/Zhang_Tingdong" title="Zhang Tingdong">Zhang Tingdong</a> and colleagues discovered this use.<sup id="cite_ref-dfp_17-0" class="reference"><a href="#cite_note-dfp-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> It was approved for leukemia treatment in the United States in 2000.<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> <a href="/wiki/University_of_Hong_Kong" title="University of Hong Kong">University of Hong Kong</a> developed a liquid form of arsenic trioxide that can be given by mouth.<sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Organoarsenic_compound" class="mw-redirect" title="Organoarsenic compound">Organoarsenic compounds</a>, such as feed additives (<a href="/wiki/Roxarsone" title="Roxarsone">roxarsone</a>) and medication (<a href="/wiki/Neosalvarsan" title="Neosalvarsan">neosalvarsan</a>), are derived from arsenic trioxide.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (July 2020)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Manufacturing">Manufacturing</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=3" title="Edit section: Manufacturing"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Industrial uses include usage as a precursor to forestry products, in colorless glass production, and in electronics.<sup id="cite_ref-Ullmann_11-1" class="reference"><a href="#cite_note-Ullmann-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Being the main compound of <a href="/wiki/Arsenic" title="Arsenic">arsenic</a>, the trioxide is the precursor to elemental arsenic, arsenic alloys, and <a href="/wiki/Arsenide" title="Arsenide">arsenide</a> <a href="/wiki/Semiconductors" class="mw-redirect" title="Semiconductors">semiconductors</a>. Bulk arsenic-based compounds <a href="/wiki/Sodium_arsenite" title="Sodium arsenite">sodium arsenite</a> and <a href="/wiki/Sodium_cacodylate" class="mw-redirect" title="Sodium cacodylate">sodium cacodylate</a> are derived from the trioxide.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (July 2020)">citation needed</span></a></i>]</sup> </p><p>A variety of applications exploit arsenic's toxicity, including the use of the oxide as a <a href="/wiki/Wood_preservative" class="mw-redirect" title="Wood preservative">wood preservative</a>. <a href="/wiki/Copper_arsenate" class="mw-redirect" title="Copper arsenate">Copper arsenates</a>, which are derived from arsenic trioxide, are used on a large scale as a wood preservative in the U.S. and Malaysia, but such materials are banned in many parts of the world. This practice remains controversial.<sup id="cite_ref-Ullmann_11-2" class="reference"><a href="#cite_note-Ullmann-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> In combination with <a href="/wiki/Copper(II)_acetate" title="Copper(II) acetate">copper(II) acetate</a>, arsenic trioxide gives the vibrant pigment known as <a href="/wiki/Paris_green" title="Paris green">Paris green</a> used in paints and as a rodenticide. This application has been discontinued.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (July 2020)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Alternative_medicine">Alternative medicine</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=4" title="Edit section: Alternative medicine"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Despite the well known toxicity of arsenic, arsenic trioxide was used in <a href="/wiki/Traditional_Chinese_medicine" title="Traditional Chinese medicine">traditional Chinese medicine</a>, where it is known as <i>pi-shuang</i> (<a href="/wiki/Chinese_language" title="Chinese language">Chinese</a>: <span lang="zh">砒霜</span>; <a href="/wiki/Pinyin" class="mw-redirect" title="Pinyin">pinyin</a>: <i><span lang="zh-Latn">pīshuāng</span></i>; <abbr title="Literal translation"><small>lit.</small></abbr> 'arsenic frost'). In <a href="/wiki/Homeopathy" title="Homeopathy">homeopathy</a>, it is called <a href="/wiki/Arsenicum_album" title="Arsenicum album">arsenicum album</a>. Some discredited <a href="/wiki/Patent_medicine" title="Patent medicine">patent medicines</a>, e.g., <a href="/wiki/Fowler%27s_solution" title="Fowler's solution">Fowler's solution</a>, contained derivatives of arsenic oxide.<sup id="cite_ref-ITOM_20-0" class="reference"><a href="#cite_note-ITOM-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Toxicology">Toxicology</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=5" title="Edit section: Toxicology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">See also: <a href="/wiki/Arsenic_poisoning" title="Arsenic poisoning">Arsenic poisoning</a></div> <p>As with other inorganic arsenic compounds, arsenic trioxide is toxic to living organisms. Arsenic trioxide is readily absorbed by the digestive system. Ingestion of as little as 0.1 grams can be fatal.<sup id="cite_ref-Ullmann_11-3" class="reference"><a href="#cite_note-Ullmann-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>Chronic arsenic poisoning is known as arsenicosis. This disorder affects workers in <a href="/wiki/Smelters" class="mw-redirect" title="Smelters">smelters</a>, in populations whose <a href="/wiki/Drinking_water" title="Drinking water">drinking water</a> contains high levels of arsenic (0.3–0.4 ppm), and in patients treated for long periods with arsenic-based pharmaceuticals. Long-term ingestion of arsenic trioxide either in drinking water or as a medical treatment can lead to skin cancer. Reproductive problems (high incidences of miscarriage, low birth weight, congenital deformations) have also been indicated in one study of women exposed to arsenic trioxide dust as employees or neighbours of a copper foundry. </p><p>In the U.S., the <a href="/wiki/Occupational_Safety_and_Health_Administration" title="Occupational Safety and Health Administration">OSHA</a> 1910.1018 occupational <a href="/wiki/Permissible_exposure_limit" title="Permissible exposure limit">permissible exposure limit</a> for inorganic arsenic compounds in <a href="/w/index.php?title=Breathing_zone&action=edit&redlink=1" class="new" title="Breathing zone (page does not exist)">breathing zone</a> air is 0.010 mg/m<sup>3</sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Production_and_occurrence">Production and occurrence</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=6" title="Edit section: Production and occurrence"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/File:St.BlasenArsenikstollen5.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/69/St.BlasenArsenikstollen5.jpg/170px-St.BlasenArsenikstollen5.jpg" decoding="async" width="170" height="302" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/69/St.BlasenArsenikstollen5.jpg/255px-St.BlasenArsenikstollen5.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/69/St.BlasenArsenikstollen5.jpg/340px-St.BlasenArsenikstollen5.jpg 2x" data-file-width="2736" data-file-height="4864" /></a><figcaption>Historic arsenic mine <a href="/wiki/Sankt_Blasen" title="Sankt Blasen">Sankt Blasen</a>, Austria</figcaption></figure> <p>Arsenic trioxide can be generated via routine processing of arsenic compounds including the oxidation (combustion) of arsenic and arsenic-containing minerals in <a href="/wiki/Air" class="mw-redirect" title="Air">air</a>. Illustrative is the roasting of <a href="/wiki/Orpiment" title="Orpiment">orpiment</a>, a typical arsenic sulfide ore. </p> <dl><dd>2 <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>S<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span> + 9 <span class="chemf nowrap">O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span></span> → 2 <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span> + 6 <span class="chemf nowrap">SO<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span></span></dd></dl> <p>Most arsenic oxide is, however, obtained as a volatile by-product of the processing of other ores. For example, <a href="/wiki/Arsenopyrite" title="Arsenopyrite">arsenopyrite</a>, a common impurity in gold- and copper-containing ores, liberates arsenic trioxide upon heating in air. The processing of such minerals has led to numerous cases of poisonings,<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> and after the mine is closed, the leftover trioxide waste will present environmental hazard (as was the case with the <a href="/wiki/Giant_Mine" title="Giant Mine">Giant Mine</a>, for example). Only in China are arsenic ores intentionally mined.<sup id="cite_ref-Ullmann_11-4" class="reference"><a href="#cite_note-Ullmann-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>In the laboratory, it is prepared by hydrolysis of <a href="/wiki/Arsenic_trichloride" title="Arsenic trichloride">arsenic trichloride</a>:<sup id="cite_ref-Brauer_22-0" class="reference"><a href="#cite_note-Brauer-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> </p> <dl><dd><style data-mw-deduplicate="TemplateStyles:r1123817410">.mw-parser-output .template-chem2-su{display:inline-block;font-size:80%;line-height:1;vertical-align:-0.35em}.mw-parser-output .template-chem2-su>span{display:block;text-align:left}.mw-parser-output sub.template-chem2-sub{font-size:80%;vertical-align:-0.35em}.mw-parser-output sup.template-chem2-sup{font-size:80%;vertical-align:0.65em}</style><span class="chemf nowrap">2 AsCl<sub class="template-chem2-sub">3</sub> + 3 H<sub class="template-chem2-sub">2</sub>O → As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">3</sub> + 6 HCl</span></dd></dl> <p><span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span> occurs naturally as two minerals, <a href="/wiki/Arsenolite" title="Arsenolite">arsenolite</a> (<a href="/wiki/Cubic_crystal_system" title="Cubic crystal system">cubic</a>) and <a href="/wiki/Claudetite" title="Claudetite">claudetite</a> (<a href="/wiki/Monoclinic" class="mw-redirect" title="Monoclinic">monoclinic</a>). Both are relatively rare secondary minerals found in <a href="/wiki/Oxidation" class="mw-redirect" title="Oxidation">oxidation</a> zones of As-rich ore deposits. </p> <div class="mw-heading mw-heading2"><h2 id="Properties_and_reactions">Properties and reactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=7" title="Edit section: Properties and reactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Arsenic trioxide is an <a href="/wiki/Amphoteric" class="mw-redirect" title="Amphoteric">amphoteric</a> oxide, and its aqueous solutions are weakly <a href="/wiki/Acidic_oxide" title="Acidic oxide">acidic</a>. Thus, it dissolves readily in alkaline solutions to give <a href="/wiki/Arsenite" title="Arsenite">arsenites</a>. It is less soluble in acids, although it will dissolve in <a href="/wiki/Hydrochloric_acid" title="Hydrochloric acid">hydrochloric acid</a>.<sup id="cite_ref-G&W_23-0" class="reference"><a href="#cite_note-G&W-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> </p><p>With anhydrous HF and HCl, it gives <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1123817410"><span class="chemf nowrap">AsF<sub class="template-chem2-sub">3</sub></span> and the trichloride:<sup id="cite_ref-Brauer_22-1" class="reference"><a href="#cite_note-Brauer-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> </p> <dl><dd><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1123817410"><span class="chemf nowrap">As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">3</sub> + 6 HX → 2 AsX<sub class="template-chem2-sub">3</sub> + 3 H<sub class="template-chem2-sub">2</sub>O</span> (X = F, Cl)</dd></dl> <p>Only with strong <a href="/wiki/Oxidizing_agent" title="Oxidizing agent">oxidizing agents</a> such as <a href="/wiki/Ozone" title="Ozone">ozone</a>, <a href="/wiki/Hydrogen_peroxide" title="Hydrogen peroxide">hydrogen peroxide</a>, and <a href="/wiki/Nitric_acid" title="Nitric acid">nitric acid</a> does it yield <a href="/wiki/Arsenic_pentoxide" title="Arsenic pentoxide">arsenic pentoxide</a>, <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">5</sub></span></span></span> or its corresponding acid:<sup id="cite_ref-Brauer_22-2" class="reference"><a href="#cite_note-Brauer-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> </p> <dl><dd><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1123817410"><span class="chemf nowrap">2 HNO<sub class="template-chem2-sub">3</sub> + As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">3</sub> + 2 H<sub class="template-chem2-sub">2</sub>O → 2 H<sub class="template-chem2-sub">3</sub>AsO<sub class="template-chem2-sub">4</sub> + N<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">3</sub></span></dd></dl> <p>In terms of its resistance to oxidation, arsenic trioxide differs from <a href="/wiki/Phosphorus_trioxide" title="Phosphorus trioxide">phosphorus trioxide</a>, which readily combusts to <a href="/wiki/Phosphorus_pentoxide" title="Phosphorus pentoxide">phosphorus pentoxide</a>. </p><p>Reduction gives elemental arsenic or <a href="/wiki/Arsine" title="Arsine">arsine</a> (<span class="chemf nowrap">AsH<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span>) depending on conditions:<sup id="cite_ref-Brauer_22-3" class="reference"><a href="#cite_note-Brauer-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> </p> <dl><dd><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1123817410"><span class="chemf nowrap">As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">3</sub> + 6 Zn + 12 HNO<sub class="template-chem2-sub">3</sub> → 2 AsH<sub class="template-chem2-sub">3</sub> + 6 Zn(NO<sub class="template-chem2-sub">3</sub>)<sub class="template-chem2-sub">2</sub> + 3 H<sub class="template-chem2-sub">2</sub>O</span></dd></dl> <p>This reaction is used in the <a href="/wiki/Marsh_test" title="Marsh test">Marsh test</a>. </p> <div class="mw-heading mw-heading3"><h3 id="Structure">Structure</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=8" title="Edit section: Structure"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In the liquid and gas phase below 800 °C, arsenic trioxide has the formula <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">4</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">6</sub></span></span></span> and is isostructural with <span class="chemf nowrap"><a href="/wiki/Phosphorus_trioxide" title="Phosphorus trioxide">P<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">4</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">6</sub></span></span></a></span>. Above 800 °C <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">4</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">6</sub></span></span></span> significantly dissociates into molecular <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span>, which adopts the same structure as <span class="chemf nowrap"><a href="/wiki/Dinitrogen_trioxide" title="Dinitrogen trioxide">N<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">2</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></a></span>. Three forms (<a href="/wiki/Polymorphism_(materials_science)" class="mw-redirect" title="Polymorphism (materials science)">polymorphs</a>) are known in the solid state: a high temperature ( > 110 °C) cubic <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">4</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">6</sub></span></span></span>, containing molecular <span class="chemf nowrap">As<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">4</sub></span></span>O<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">6</sub></span></span></span>, and two related polymeric forms.<sup id="cite_ref-Wells_24-0" class="reference"><a href="#cite_note-Wells-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> The polymers, which both crystallize as monoclinic crystals, feature sheets of pyramidal <span class="chemf nowrap">AsO<span class="nowrap"><span style="display:inline-block;margin-bottom:-0.3em;vertical-align:-0.4em;line-height:1em;font-size:80%;text-align:left"><sup style="font-size:inherit;line-height:inherit;vertical-align:baseline"></sup><br /><sub style="font-size:inherit;line-height:inherit;vertical-align:baseline">3</sub></span></span></span> units that share O atoms.<sup id="cite_ref-Wiberg&Holleman_25-0" class="reference"><a href="#cite_note-Wiberg&Holleman-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> </p> <table align="center" class="wikitable"> <tbody><tr> <td><span typeof="mw:File"><a href="/wiki/File:Arsenolite-xtal-3D-balls-D.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Arsenolite-xtal-3D-balls-D.png/170px-Arsenolite-xtal-3D-balls-D.png" decoding="async" width="170" height="145" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Arsenolite-xtal-3D-balls-D.png/255px-Arsenolite-xtal-3D-balls-D.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Arsenolite-xtal-3D-balls-D.png/340px-Arsenolite-xtal-3D-balls-D.png 2x" data-file-width="1100" data-file-height="935" /></a></span> </td> <td><span typeof="mw:File"><a href="/wiki/File:Claudetite-I-layer-3D-balls.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/46/Claudetite-I-layer-3D-balls.png/150px-Claudetite-I-layer-3D-balls.png" decoding="async" width="150" height="131" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/46/Claudetite-I-layer-3D-balls.png/225px-Claudetite-I-layer-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/46/Claudetite-I-layer-3D-balls.png/300px-Claudetite-I-layer-3D-balls.png 2x" data-file-width="1100" data-file-height="964" /></a></span> </td> <td><span typeof="mw:File"><a href="/wiki/File:Claudetite-II-layer-3D-balls.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/be/Claudetite-II-layer-3D-balls.png/220px-Claudetite-II-layer-3D-balls.png" decoding="async" width="220" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/be/Claudetite-II-layer-3D-balls.png/330px-Claudetite-II-layer-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/be/Claudetite-II-layer-3D-balls.png/440px-Claudetite-II-layer-3D-balls.png 2x" data-file-width="1100" data-file-height="677" /></a></span> </td></tr> <tr> <td><div class="center" style="width:auto; margin-left:auto; margin-right:auto;">arsenolite<br />(cubic)</div></td> <td><div class="center" style="width:auto; margin-left:auto; margin-right:auto;">claudetite I<br />(monoclinic)</div></td> <td><div class="center" style="width:auto; margin-left:auto; margin-right:auto;">claudetite II<br />(monoclinic)</div> </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Society_and_culture">Society and culture</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=9" title="Edit section: Society and culture"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Environmental_effects">Environmental effects</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=10" title="Edit section: Environmental effects"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Smelting" title="Smelting">Smelting</a> and related ore processing often generate arsenic trioxide, which poses a risk to the <a href="/wiki/Environment_(biophysical)" class="mw-redirect" title="Environment (biophysical)">environment</a>. For example, the <a href="/wiki/Giant_Mine" title="Giant Mine">Giant Mine</a> in Canada processed substantial amounts of <a href="/wiki/Arsenopyrite" title="Arsenopyrite">arsenopyrite</a>-contaminated gold ores. </p> <div class="mw-heading mw-heading3"><h3 id="Arsenic_poisoning_in_literature_and_society">Arsenic poisoning in literature and society</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=11" title="Edit section: Arsenic poisoning in literature and society"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Arsenic_poisoning" title="Arsenic poisoning">Arsenic poisoning</a></div> <p>The poisonous properties of arsenic are the subject of an extensive literature.<sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Murder_27-0" class="reference"><a href="#cite_note-Murder-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> </p><p>In Austria, there lived the so-called "arsenic eaters of <a href="/wiki/Styria" title="Styria">Styria</a>", who ingested doses far beyond the lethal dose of arsenic trioxide without any apparent harm. Arsenic is thought to enable strenuous work at high altitudes, e.g. in the Alps.<sup id="cite_ref-29" class="reference"><a href="#cite_note-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-32" class="reference"><a href="#cite_note-32"><span class="cite-bracket">[</span>32<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=12" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFShakhashiri" class="citation web cs1">Shakhashiri BZ. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20080802165618/http://scifun.chem.wisc.edu/chemweek/Arsenic/Arsenic.html">"Chemical of the Week: Arsenic"</a>. University of Wisconsin-Madison Chemistry Dept. Archived from <a rel="nofollow" class="external text" href="http://scifun.chem.wisc.edu/chemweek/Arsenic/Arsenic.html">the original</a> on 2 August 2008<span class="reference-accessdate">. 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Retrieved <span class="nowrap">3 February</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=DailyMed&rft.atitle=Trisenox-+arsenic+trioxide+injection%2C+solution&rft.date=2022-06-30&rft_id=https%3A%2F%2Fdailymed.nlm.nih.gov%2Fdailymed%2FdrugInfo.cfm%3Fsetid%3D101fc347-d0ad-4aee-8b06-9feb187fd741&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-Trisenox_EPAR-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-Trisenox_EPAR_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Trisenox_EPAR_3-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Trisenox_EPAR_3-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ema.europa.eu/en/medicines/human/EPAR/trisenox">"Trisenox EPAR"</a>. <i>European Medicines Agency</i>. 10 August 2010. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230816204715/https://www.ema.europa.eu/en/medicines/human/EPAR/trisenox">Archived</a> from the original on 16 August 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">3 February</span> 2024</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=European+Medicines+Agency&rft.atitle=Trisenox+EPAR&rft.date=2010-08-10&rft_id=https%3A%2F%2Fwww.ema.europa.eu%2Fen%2Fmedicines%2Fhuman%2FEPAR%2Ftrisenox&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.americanelements.com/printpdf/arsenic-iii-oxide-1327-53-3/sds">"Safety Data Sheet"</a>. American Elements. 2021. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220104114537/https://www.americanelements.com/printpdf/arsenic-iii-oxide-1327-53-3/sds">Archived</a> from the original on 4 January 2022<span class="reference-accessdate">. Retrieved <span class="nowrap">4 January</span> 2022</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Safety+Data+Sheet&rft.pub=American+Elements&rft.date=2021&rft_id=https%3A%2F%2Fwww.americanelements.com%2Fprintpdf%2Farsenic-iii-oxide-1327-53-3%2Fsds&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSun2010" class="citation book cs1">Sun H (2010). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=nrKXcXQF0QAC&pg=PA295"><i>Biological Chemistry of Arsenic, Antimony and Bismuth</i></a>. John Wiley & Sons. p. 295. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780470976227" title="Special:BookSources/9780470976227"><bdi>9780470976227</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230414173127/https://books.google.com/books?id=nrKXcXQF0QAC&pg=PA295">Archived</a> from the original on 14 April 2023<span class="reference-accessdate">. Retrieved <span class="nowrap">18 March</span> 2023</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Biological+Chemistry+of+Arsenic%2C+Antimony+and+Bismuth&rft.pages=295&rft.pub=John+Wiley+%26+Sons&rft.date=2010&rft.isbn=9780470976227&rft.aulast=Sun&rft.aufirst=H&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DnrKXcXQF0QAC%26pg%3DPA295&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-Land2012-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-Land2012_6-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLandner2012" class="citation book cs1">Landner L (2012). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=wZb6CAAAQBAJ&dq=Arsenic+trioxide+industrial+chemical&pg=PA259"><i>Chemicals in the Aquatic Environment: Advanced Hazard Assessment</i></a>. Springer Science & Business Media. p. 259. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9783642613340" title="Special:BookSources/9783642613340"><bdi>9783642613340</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20230414173125/https://books.google.com/books?id=wZb6CAAAQBAJ&dq=Arsenic+trioxide+industrial+chemical&pg=PA259">Archived</a> from the original on 14 April 2023<span class="reference-accessdate">. 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(July 2003). <a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood-2003-01-0298">"Oral arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia"</a>. <i>Blood</i>. <b>102</b> (1): 407–408. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood-2003-01-0298">10.1182/blood-2003-01-0298</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12814916">12814916</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Blood&rft.atitle=Oral+arsenic+trioxide+in+the+treatment+of+relapsed+acute+promyelocytic+leukemia&rft.volume=102&rft.issue=1&rft.pages=407-408&rft.date=2003-07&rft_id=info%3Adoi%2F10.1182%2Fblood-2003-01-0298&rft_id=info%3Apmid%2F12814916&rft.aulast=Au&rft.aufirst=WY&rft.au=Kumana%2C+CR&rft.au=Kou%2C+M&rft.au=Mak%2C+R&rft.au=Chan%2C+GC&rft.au=Lam%2C+CW&rft.au=Kwong%2C+YL&rft_id=https%3A%2F%2Fdoi.org%2F10.1182%252Fblood-2003-01-0298&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-ITOM-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-ITOM_20-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGibaudJaouen2010" class="citation book cs1">Gibaud S, Jaouen G (2010). "Arsenic-Based Drugs: From Fowler's Solution to Modern Anticancer Chemotherapy". <i>Medicinal Organometallic Chemistry</i>. Topics in Organometallic Chemistry. Vol. 32. pp. 1–20. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2010moc..book....1G">2010moc..book....1G</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2F978-3-642-13185-1_1">10.1007/978-3-642-13185-1_1</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-3-642-13184-4" title="Special:BookSources/978-3-642-13184-4"><bdi>978-3-642-13184-4</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Arsenic-Based+Drugs%3A+From+Fowler%27s+Solution+to+Modern+Anticancer+Chemotherapy&rft.btitle=Medicinal+Organometallic+Chemistry&rft.series=Topics+in+Organometallic+Chemistry&rft.pages=1-20&rft.date=2010&rft_id=info%3Adoi%2F10.1007%2F978-3-642-13185-1_1&rft_id=info%3Abibcode%2F2010moc..book....1G&rft.isbn=978-3-642-13184-4&rft.aulast=Gibaud&rft.aufirst=S&rft.au=Jaouen%2C+G&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-21">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20060627075016/http://nwt-tno.inac-ainc.gc.ca/giant/atg_e.html">"Giant Mine – Northwest Territories Region – Indian and Northern Affairs Canada"</a>. Archived from <a rel="nofollow" class="external text" href="http://nwt-tno.inac-ainc.gc.ca/giant/atg_e.html">the original</a> on 27 June 2006<span class="reference-accessdate">. Retrieved <span class="nowrap">28 August</span> 2007</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Giant+Mine+%E2%80%93+Northwest+Territories+Region+%E2%80%93+Indian+and+Northern+Affairs+Canada&rft_id=http%3A%2F%2Fnwt-tno.inac-ainc.gc.ca%2Fgiant%2Fatg_e.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-Brauer-22"><span class="mw-cite-backlink">^ <a href="#cite_ref-Brauer_22-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Brauer_22-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Brauer_22-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Brauer_22-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text">Handbook of Preparative Inorganic Chemistry, 2nd Ed. Edited by G. Brauer, Academic Press, 1963, NY.</span> </li> <li id="cite_note-G&W-23"><span class="mw-cite-backlink"><b><a href="#cite_ref-G&W_23-0">^</a></b></span> <span class="reference-text">Greenwood, N. N.; & Earnshaw, A. (1997). Chemistry of the Elements (2nd Edn.), Oxford:Butterworth-Heinemann. <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-7506-3365-4" title="Special:BookSources/0-7506-3365-4">0-7506-3365-4</a>.</span> </li> <li id="cite_note-Wells-24"><span class="mw-cite-backlink"><b><a href="#cite_ref-Wells_24-0">^</a></b></span> <span class="reference-text">Wells A.F. Structural Inorganic Chemistry. 5th. London, England: Oxford University Press, 1984. Print. <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-19-855370-6" title="Special:BookSources/0-19-855370-6">0-19-855370-6</a></span> </li> <li id="cite_note-Wiberg&Holleman-25"><span class="mw-cite-backlink"><b><a href="#cite_ref-Wiberg&Holleman_25-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHollemanWiberg2001" class="citation book cs1">Holleman AF, Wiberg E (2001). <i>Inorganic Chemistry</i>. San Diego: Academic Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-12-352651-5" title="Special:BookSources/0-12-352651-5"><bdi>0-12-352651-5</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Inorganic+Chemistry&rft.place=San+Diego&rft.pub=Academic+Press&rft.date=2001&rft.isbn=0-12-352651-5&rft.aulast=Holleman&rft.aufirst=AF&rft.au=Wiberg%2C+E&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-26"><span class="mw-cite-backlink"><b><a href="#cite_ref-26">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://caselaw.lp.findlaw.com/scripts/getcase.pl?navby=search&case=/data2/circs/9th/9716830.html&friend=usatoday">"Stanton v Benzler 9716830"</a>. U.S. 9th Circuit Court of Appeals. 17 June 1998. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20121021053846/http://caselaw.lp.findlaw.com/scripts/getcase.pl?navby=search&case=/data2/circs/9th/9716830.html&friend=usatoday">Archived</a> from the original on 21 October 2012<span class="reference-accessdate">. Retrieved <span class="nowrap">9 June</span> 2008</span>. <q>(...) convicted by a jury of first degree murder for poisoning her ex-husband. Her ex-husband's body was found with traces of arsenic trioxide in it.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Stanton+v+Benzler+9716830&rft.pub=U.S.+9th+Circuit+Court+of+Appeals&rft.date=1998-06-17&rft_id=http%3A%2F%2Fcaselaw.lp.findlaw.com%2Fscripts%2Fgetcase.pl%3Fnavby%3Dsearch%26case%3D%2Fdata2%2Fcircs%2F9th%2F9716830.html%26friend%3Dusatoday&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-Murder-27"><span class="mw-cite-backlink"><b><a href="#cite_ref-Murder_27-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFEmsley2006" class="citation book cs1">Emsley J (2006). "Arsenic". <i>The Elements of Murder: A History of Poison</i>. <a href="/wiki/Oxford_University_Press" title="Oxford University Press">Oxford University Press</a>. pp. 93–197. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-19-280600-0" title="Special:BookSources/978-0-19-280600-0"><bdi>978-0-19-280600-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Arsenic&rft.btitle=The+Elements+of+Murder%3A+A+History+of+Poison&rft.pages=93-197&rft.pub=Oxford+University+Press&rft.date=2006&rft.isbn=978-0-19-280600-0&rft.aulast=Emsley&rft.aufirst=J&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-28"><span class="mw-cite-backlink"><b><a href="#cite_ref-28">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFlaubert1856" class="citation book cs1"><a href="/wiki/Gustave_Flaubert" title="Gustave Flaubert">Flaubert G</a> (1856). <i><a href="/wiki/Madame_Bovary" title="Madame Bovary">Madame Bovary</a></i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Madame+Bovary&rft.date=1856&rft.aulast=Flaubert&rft.aufirst=G&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-29"><span class="mw-cite-backlink"><b><a href="#cite_ref-29">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="https://www.nytimes.com/1885/07/26/archives/arsenic-eaters.html">"Arsenic Eaters"</a>. <i><a href="/wiki/The_New_York_Times" title="The New York Times">The New York Times</a></i>. 26 July 1885. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20180727150147/https://www.nytimes.com/1885/07/26/archives/arsenic-eaters.html">Archived</a> from the original on 27 July 2018<span class="reference-accessdate">. Retrieved <span class="nowrap">27 July</span> 2018</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Arsenic+Eaters&rft.date=1885-07-26&rft_id=https%3A%2F%2Fwww.nytimes.com%2F1885%2F07%2F26%2Farchives%2Farsenic-eaters.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-30"><span class="mw-cite-backlink"><b><a href="#cite_ref-30">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAllesch1959" class="citation book cs1">Allesch RM (1959). <i>Arsenik. Seine Geschichte in Österreich</i>. Archiv für vaterländische Geschichte und Topographie. Vol. 54. Klagenfurt: Kleinmayr.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Arsenik.+Seine+Geschichte+in+%C3%96sterreich&rft.place=Klagenfurt&rft.series=Archiv+f%C3%BCr+vaterl%C3%A4ndische+Geschichte+und+Topographie&rft.pub=Kleinmayr&rft.date=1959&rft.aulast=Allesch&rft.aufirst=RM&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-31"><span class="mw-cite-backlink"><b><a href="#cite_ref-31">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPrzygodaFeldmannCullen2001" class="citation journal cs1">Przygoda G, Feldmann J, Cullen WR (2001). "The arsenic eaters of Styria: a different picture of people who were chronically exposed to arsenic". <i>Applied Organometallic Chemistry</i>. <b>15</b> (6): 457–462. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Faoc.126">10.1002/aoc.126</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Applied+Organometallic+Chemistry&rft.atitle=The+arsenic+eaters+of+Styria%3A+a+different+picture+of+people+who+were+chronically+exposed+to+arsenic&rft.volume=15&rft.issue=6&rft.pages=457-462&rft.date=2001&rft_id=info%3Adoi%2F10.1002%2Faoc.126&rft.aulast=Przygoda&rft.aufirst=G&rft.au=Feldmann%2C+J&rft.au=Cullen%2C+WR&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> <li id="cite_note-32"><span class="mw-cite-backlink"><b><a href="#cite_ref-32">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWhorton2010" class="citation book cs1">Whorton JC (2010). <span class="id-lock-limited" title="Free access subject to limited trial, subscription normally required"><a rel="nofollow" class="external text" href="https://archive.org/details/arseniccenturyho00whor"><i>The Arsenic Century</i></a></span>. <a href="/wiki/Oxford_University_Press" title="Oxford University Press">Oxford University Press</a>. pp. <a rel="nofollow" class="external text" href="https://archive.org/details/arseniccenturyho00whor/page/n292">270</a>–273. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-19-960599-6" title="Special:BookSources/978-0-19-960599-6"><bdi>978-0-19-960599-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Arsenic+Century&rft.pages=270-273&rft.pub=Oxford+University+Press&rft.date=2010&rft.isbn=978-0-19-960599-6&rft.aulast=Whorton&rft.aufirst=JC&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Farseniccenturyho00whor&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Arsenic_trioxide&action=edit&section=13" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.atsdr.cdc.gov/csem/csem.html">Case Studies in Environmental Medicine: Arsenic Toxicity</a></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.inchem.org/documents/iarc/suppl7/arsenic.html">"Arsenic and Arsenic Compounds"</a>. <i>Summaries & Evaluations</i>. International Agency for Research on Cancer (IARC). February 1998.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Summaries+%26+Evaluations&rft.atitle=Arsenic+and+Arsenic+Compounds&rft.date=1998-02&rft_id=http%3A%2F%2Fwww.inchem.org%2Fdocuments%2Fiarc%2Fsuppl7%2Farsenic.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AArsenic+trioxide" class="Z3988"></span></li> <li><a rel="nofollow" class="external text" href="http://www.inchem.org/documents/icsc/icsc/eics0378.htm">International Chemical Safety Card 0378</a></li> <li><a rel="nofollow" class="external text" href="https://www.americanelements.com/printpdf/arsenic-iii-oxide-1327-53-3/sds">Safety Data Sheet</a> from <a href="/wiki/American_Elements" title="American Elements">American Elements</a></li> <li><a rel="nofollow" class="external text" href="https://www.cdc.gov/niosh/npg/npgd0038.html">NIOSH Pocket Guide to Chemical Hazards</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20051111213656/http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s015arse.pdf">NTP Report on Carcinogens – Inorganic Arsenic Compounds</a></li> <li><a href="/wiki/Institut_national_de_recherche_et_de_s%C3%A9curit%C3%A9" title="Institut national de recherche et de sécurité">Institut national de recherche et de sécurité</a> (1989). "<a rel="nofollow" class="external text" href="http://www.inrs.fr/inrs-pub/inrs01.nsf/inrs01_ftox_view/6FF38EFEA1841E95C1256CE8005A91B1/$File/ft89.pdf">Trioxyde d'arsenic.</a>" <i>Fiche toxicologique n° 89</i>. Paris:INRS. <span class="languageicon">(in French)</span></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · 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style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output 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template">e</abbr></a></li></ul></div><div id="Intracellular_chemotherapeutic_agents_/_antineoplastic_agents_(L01)" style="font-size:114%;margin:0 4em">Intracellular <a href="/wiki/Chemotherapy" title="Chemotherapy">chemotherapeutic agents</a> / <a href="/wiki/Antineoplastic" class="mw-redirect" title="Antineoplastic">antineoplastic agents</a> (<a href="/wiki/ATC_code_L01" title="ATC code L01">L01</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Spindle_poison" title="Spindle poison">SPs</a>/<a href="/wiki/Mitotic_inhibitor" title="Mitotic inhibitor">MIs</a><br />(<a href="/wiki/M_phase" class="mw-redirect" title="M phase">M phase</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Block <a href="/wiki/Microtubule" title="Microtubule">microtubule</a> assembly</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Vinca_alkaloid" title="Vinca alkaloid">Vinca alkaloids</a></i> (<a href="/wiki/Vinblastine" title="Vinblastine">Vinblastine</a><sup>#</sup></li> <li><a href="/wiki/Vincristine" title="Vincristine">Vincristine</a><sup>#</sup></li> <li><a href="/wiki/Vindesine" title="Vindesine">Vindesine</a></li> <li><a href="/wiki/Vinflunine" title="Vinflunine">Vinflunine</a><sup>§</sup></li> <li><a href="/wiki/Vinorelbine" title="Vinorelbine">Vinorelbine</a><sup>#</sup>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Block microtubule disassembly</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Taxane" title="Taxane">Taxanes</a></i> (<a href="/wiki/Cabazitaxel" title="Cabazitaxel">Cabazitaxel</a></li> <li><a href="/wiki/Docetaxel" title="Docetaxel">Docetaxel</a><sup>#</sup></li> <li><a href="/wiki/Larotaxel" title="Larotaxel">Larotaxel</a></li> <li><a href="/wiki/Ortataxel" title="Ortataxel">Ortataxel</a><sup>†</sup></li> <li><a href="/wiki/Paclitaxel" title="Paclitaxel">Paclitaxel</a><sup>#</sup></li> <li><a href="/wiki/Tesetaxel" title="Tesetaxel">Tesetaxel</a>)</li> <li><i><a href="/wiki/Epothilone" title="Epothilone">Epothilones</a></i> (<a href="/wiki/Ixabepilone" title="Ixabepilone">Ixabepilone</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/DNA_replication" title="DNA replication">DNA replication</a><br />inhibitor</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">DNA precursors/<br /><a href="/wiki/Antimetabolite" title="Antimetabolite">antimetabolites</a><br />(<a href="/wiki/S_phase" title="S phase">S phase</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Antifolate" title="Antifolate">Folic acid</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Dihydrofolate_reductase_inhibitor" title="Dihydrofolate reductase inhibitor">Dihydrofolate reductase inhibitor</a></i> (<a href="/wiki/Aminopterin" title="Aminopterin">Aminopterin</a></li> <li><a href="/wiki/Methotrexate" title="Methotrexate">Methotrexate</a><sup>#</sup></li> <li><a href="/wiki/Pemetrexed" title="Pemetrexed">Pemetrexed</a></li> <li><a href="/wiki/Pralatrexate" title="Pralatrexate">Pralatrexate</a>)</li> <li><i><a href="/wiki/Thymidylate_synthase_inhibitor" title="Thymidylate synthase inhibitor">Thymidylate synthase inhibitor</a></i> (<a href="/wiki/Pemetrexed" title="Pemetrexed">Pemetrexed</a></li> <li><a href="/wiki/Raltitrexed" title="Raltitrexed">Raltitrexed</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Purine_analogue" title="Purine analogue">Purine</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Adenosine_deaminase_inhibitor" class="mw-redirect" title="Adenosine deaminase inhibitor">Adenosine deaminase inhibitor</a></i> (<a href="/wiki/Pentostatin" title="Pentostatin">Pentostatin</a>)</li></ul> <ul><li><i><a href="/wiki/Halogenation" title="Halogenation">Halogenated</a>/<a href="/wiki/Ribonucleotide_reductase_inhibitor" title="Ribonucleotide reductase inhibitor">ribonucleotide reductase inhibitors</a></i> (<a href="/wiki/Cladribine" title="Cladribine">Cladribine</a></li> <li><a href="/wiki/Clofarabine" title="Clofarabine">Clofarabine</a></li> <li><a href="/wiki/Fludarabine" title="Fludarabine">Fludarabine</a>)</li> <li><a href="/wiki/Nelarabine" title="Nelarabine">Nelarabine</a></li> <li><a href="/wiki/Rabacfosadine" title="Rabacfosadine">Rabacfosadine</a></li> <li><i><a href="/wiki/Thiopurine" title="Thiopurine">Thiopurine</a></i> (<a href="/wiki/Mercaptopurine" title="Mercaptopurine">Mercaptopurine</a><sup>#</sup></li> <li><a href="/wiki/Tioguanine" title="Tioguanine">Tioguanine</a><sup>#</sup>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pyrimidine_analogue" title="Pyrimidine analogue">Pyrimidine</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Thymidylate_synthase_inhibitor" title="Thymidylate synthase inhibitor">Thymidylate synthase inhibitor</a></i> (<a href="/wiki/Capecitabine" title="Capecitabine">Capecitabine</a><sup>#</sup></li> <li><a href="/wiki/Carmofur" title="Carmofur">Carmofur</a></li> <li><a href="/wiki/Doxifluridine" title="Doxifluridine">Doxifluridine</a></li> <li><a href="/wiki/Floxuridine" title="Floxuridine">Floxuridine</a></li> <li><a href="/wiki/Fluorouracil" title="Fluorouracil">Fluorouracil</a><sup>#</sup></li> <li><a href="/wiki/Tegafur" title="Tegafur">Tegafur</a> (<a href="/wiki/Tegafur/gimeracil/oteracil" title="Tegafur/gimeracil/oteracil">+gimeracil/oteracil</a>))</li></ul> <ul><li><i><a href="/wiki/DNA_polymerase_inhibitor" class="mw-redirect" title="DNA polymerase inhibitor">DNA polymerase inhibitor</a></i> (<a href="/wiki/Cytarabine" title="Cytarabine">Cytarabine</a><sup>#</sup> <a href="/wiki/Daunorubicin/cytarabine" title="Daunorubicin/cytarabine">+daunorubicin</a>)</li></ul> <ul><li><i><a href="/wiki/Ribonucleotide_reductase_inhibitor" title="Ribonucleotide reductase inhibitor">Ribonucleotide reductase inhibitor</a></i> (<a href="/wiki/Gemcitabine" title="Gemcitabine">Gemcitabine</a><sup>#</sup>)</li></ul> <ul><li><i><a href="/wiki/Hypomethylating_agent" title="Hypomethylating agent">Hypomethylating agent</a></i> (<a href="/wiki/Azacitidine" title="Azacitidine">Azacitidine</a></li> <li><a href="/wiki/Decitabine" title="Decitabine">Decitabine</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Deoxyribonucleotide" title="Deoxyribonucleotide">Deoxyribonucleotide</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Ribonucleotide_reductase_inhibitor" title="Ribonucleotide reductase inhibitor">Ribonucleotide reductase inhibitor</a></i> (<a href="/wiki/Hydroxycarbamide" title="Hydroxycarbamide">Hydroxycarbamide</a><sup>#</sup>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Topoisomerase_inhibitor" title="Topoisomerase inhibitor">Topoisomerase inhibitors</a><br />(<a href="/wiki/S_phase" title="S phase">S phase</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Type_I_topoisomerase#Inhibition" title="Type I topoisomerase">I</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Camptotheca" title="Camptotheca">Camptotheca</a></i> (<a href="/wiki/Belotecan" title="Belotecan">Belotecan</a></li> <li><a href="/wiki/Camptothecin" title="Camptothecin">Camptothecin</a></li> <li><a href="/w/index.php?title=Cositecan&action=edit&redlink=1" class="new" title="Cositecan (page does not exist)">Cositecan</a><sup>†</sup></li> <li><a href="/wiki/Etirinotecan_pegol" title="Etirinotecan pegol">Etirinotecan pegol</a><sup>†</sup></li> <li><a href="/wiki/Exatecan" title="Exatecan">Exatecan</a></li> <li><a href="/w/index.php?title=Gimatecan&action=edit&redlink=1" class="new" title="Gimatecan (page does not exist)">Gimatecan</a></li> <li><a href="/wiki/Irinotecan" title="Irinotecan">Irinotecan</a><sup>#</sup></li> <li><a href="/wiki/Lurtotecan" title="Lurtotecan">Lurtotecan</a><sup>‡</sup></li> <li><a href="/wiki/Rubitecan" title="Rubitecan">Rubitecan</a><sup>‡</sup></li> <li><a href="/w/index.php?title=Silatecan&action=edit&redlink=1" class="new" title="Silatecan (page does not exist)">Silatecan</a><sup>§</sup></li> <li><a href="/wiki/Topotecan" title="Topotecan">Topotecan</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Type_II_topoisomerase#Inhibition" title="Type II topoisomerase">II</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Podophyllum_peltatum" title="Podophyllum peltatum">Podophyllum</a></i> (<a href="/wiki/Etoposide" title="Etoposide">Etoposide</a><sup>#</sup></li> <li><a href="/wiki/Teniposide" title="Teniposide">Teniposide</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Type_II_topoisomerase#Inhibition" title="Type II topoisomerase">II</a>+<a href="/wiki/Intercalation_(biochemistry)" title="Intercalation (biochemistry)">Intercalation</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Anthracycline" title="Anthracycline">Anthracyclines</a></i> (<a href="/wiki/Aclarubicin" title="Aclarubicin">Aclarubicin</a></li> <li><a href="/wiki/Amrubicin" title="Amrubicin">Amrubicin</a><sup>†</sup></li> <li><a href="/wiki/Daunorubicin" title="Daunorubicin">Daunorubicin</a><sup>#</sup> (<a href="/wiki/Daunorubicin/cytarabine" title="Daunorubicin/cytarabine">+cytarabine</a>)</li> <li><a href="/wiki/Doxorubicin" title="Doxorubicin">Doxorubicin</a><sup>#</sup></li> <li><a href="/wiki/Epirubicin" title="Epirubicin">Epirubicin</a></li> <li><a href="/wiki/Idarubicin" title="Idarubicin">Idarubicin</a></li> <li><a href="/wiki/Pirarubicin" title="Pirarubicin">Pirarubicin</a></li> <li><a href="/wiki/Valrubicin" title="Valrubicin">Valrubicin</a></li> <li><a href="/wiki/Zorubicin" title="Zorubicin">Zorubicin</a>)</li> <li><i><a href="/wiki/Anthraquinone" title="Anthraquinone">Anthracenediones</a></i> (<a href="/wiki/Losoxantrone" title="Losoxantrone">Losoxantrone</a></li> <li><a href="/wiki/Mitoxantrone" title="Mitoxantrone">Mitoxantrone</a></li> <li><a href="/wiki/Pixantrone" title="Pixantrone">Pixantrone</a>)</li> <li><a href="/wiki/Amsacrine" title="Amsacrine">Amsacrine</a></li> <li><a href="/wiki/Bisantrene" title="Bisantrene">Bisantrene</a></li> <li><a href="/wiki/Crisnatol" title="Crisnatol">Crisnatol</a></li> <li><a href="/wiki/Menogaril" title="Menogaril">Menogaril</a><sup>§</sup></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Crosslinking_of_DNA" title="Crosslinking of DNA">Crosslinking of DNA</a><br />(<a href="/wiki/Cell-cycle_nonspecific_antineoplastic_agents" title="Cell-cycle nonspecific antineoplastic agents">CCNS</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Alkylating_antineoplastic_agent" title="Alkylating antineoplastic agent">Alkylating</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Nitrogen_mustard" title="Nitrogen mustard">Nitrogen mustards</a>:</i> <a href="/wiki/Bendamustine" title="Bendamustine">Bendamustine</a><sup>#</sup></li> <li><a href="/wiki/Chlormethine" title="Chlormethine">Chlormethine</a></li> <li><a href="/wiki/Cyclophosphamide" title="Cyclophosphamide">Cyclophosphamide</a><sup>#</sup> (<a href="/wiki/Ifosfamide" title="Ifosfamide">Ifosfamide</a><sup>#</sup></li> <li><a href="/wiki/Trofosfamide" title="Trofosfamide">Trofosfamide</a>)</li> <li><a href="/wiki/Chlorambucil" title="Chlorambucil">Chlorambucil</a><sup>#</sup></li> <li><a href="/wiki/Melphalan" title="Melphalan">Melphalan</a> (<a href="/wiki/Melphalan_flufenamide" title="Melphalan flufenamide">Melphalan flufenamide</a>)</li> <li><a href="/wiki/Prednimustine" title="Prednimustine">Prednimustine</a></li> <li><a href="/wiki/Uramustine" title="Uramustine">Uramustine</a></li></ul> <ul><li><i><a href="/wiki/Nitrosourea" title="Nitrosourea">Nitrosoureas</a>:</i> <a href="/wiki/Carmustine" title="Carmustine">Carmustine</a></li> <li><a href="/wiki/Fotemustine" title="Fotemustine">Fotemustine</a></li> <li><a href="/wiki/Lomustine" title="Lomustine">Lomustine</a> (<a href="/wiki/Semustine" title="Semustine">Semustine</a>)</li> <li><a href="/wiki/Nimustine" title="Nimustine">Nimustine</a></li> <li><a href="/wiki/Ranimustine" title="Ranimustine">Ranimustine</a></li> <li><a href="/wiki/Streptozotocin" title="Streptozotocin">Streptozocin</a></li></ul> <ul><li><i><a href="/wiki/Alkyl_sulfonate" title="Alkyl sulfonate">Alkyl sulfonates</a>:</i> <a href="/wiki/Busulfan" title="Busulfan">Busulfan</a> (<a href="/wiki/Mannosulfan" title="Mannosulfan">Mannosulfan</a></li> <li><a href="/wiki/Treosulfan" title="Treosulfan">Treosulfan</a>)</li></ul> <ul><li><i><a href="/wiki/Aziridine" title="Aziridine">Aziridines</a>:</i> <a href="/wiki/Carboquone" title="Carboquone">Carboquone</a></li> <li><a href="/wiki/Thiotepa" title="Thiotepa">Thiotepa</a></li> <li><a href="/wiki/Triaziquone" title="Triaziquone">Triaziquone</a></li> <li><a href="/wiki/Triethylenemelamine" title="Triethylenemelamine">Triethylenemelamine</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Platinum-based_antineoplastic" title="Platinum-based antineoplastic">Platinum-based</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carboplatin" title="Carboplatin">Carboplatin</a><sup>#</sup></li> <li><a href="/wiki/Cisplatin" title="Cisplatin">Cisplatin</a><sup>#</sup></li> <li><a href="/wiki/Dicycloplatin" title="Dicycloplatin">Dicycloplatin</a></li> <li><a href="/wiki/Nedaplatin" title="Nedaplatin">Nedaplatin</a></li> <li><a href="/wiki/Oxaliplatin" title="Oxaliplatin">Oxaliplatin</a><sup>#</sup></li> <li><a href="/wiki/Satraplatin" title="Satraplatin">Satraplatin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Alkylating_antineoplastic_agent#Nonclassical" title="Alkylating antineoplastic agent">Nonclassical</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Altretamine" title="Altretamine">Altretamine</a></li> <li><i><a href="/wiki/Hydrazine" title="Hydrazine">Hydrazines</a></i> (<a href="/wiki/Procarbazine" title="Procarbazine">Procarbazine</a><sup>#</sup>)</li> <li><a href="/wiki/Etoglucid" title="Etoglucid">Etoglucid</a></li> <li><a href="/wiki/Mitobronitol" title="Mitobronitol">Mitobronitol</a></li> <li><a href="/wiki/Pipobroman" title="Pipobroman">Pipobroman</a></li> <li><i><a href="/wiki/Triazene" title="Triazene">Triazenes</a></i> (<a href="/wiki/Dacarbazine" title="Dacarbazine">Dacarbazine</a><sup>#</sup></li> <li><a href="/wiki/Mitozolomide" title="Mitozolomide">Mitozolomide</a><sup>§</sup></li> <li><a href="/wiki/Temozolomide" title="Temozolomide">Temozolomide</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Intercalation_(biochemistry)" title="Intercalation (biochemistry)">Intercalation</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Streptomyces" title="Streptomyces">Streptomyces</a> (<a href="/wiki/Dactinomycin" title="Dactinomycin">Dactinomycin</a><sup>#</sup></li> <li><a href="/wiki/Bleomycin" title="Bleomycin">Bleomycin</a><sup>#</sup></li> <li><a href="/wiki/Mitomycins" title="Mitomycins">Mitomycins</a></li> <li><a href="/wiki/Plicamycin" title="Plicamycin">Plicamycin</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Photosensitizer" title="Photosensitizer">Photosensitizers</a>/<a href="/wiki/Photodynamic_therapy" title="Photodynamic therapy">PDT</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aminolevulinic_acid" title="Aminolevulinic acid">Aminolevulinic acid</a></li> <li><a href="/wiki/Efaproxiral" title="Efaproxiral">Efaproxiral</a></li> <li><a href="/wiki/Methyl_aminolevulinate" title="Methyl aminolevulinate">Methyl aminolevulinate</a></li> <li><a href="/wiki/Padeliporfin" title="Padeliporfin">Padeliporfin</a></li> <li><i><a href="/wiki/Porphyrin" title="Porphyrin">Porphyrin derivatives</a></i> (<a href="/wiki/Porfimer_sodium" title="Porfimer sodium">Porfimer sodium</a></li> <li><a href="/wiki/Talaporfin" title="Talaporfin">Talaporfin</a></li> <li><a href="/wiki/Temoporfin" title="Temoporfin">Temoporfin</a></li> <li><a href="/wiki/Verteporfin" title="Verteporfin">Verteporfin</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Enzyme_inhibitor" title="Enzyme inhibitor">Enzyme inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Farnesyltransferase_inhibitor" title="Farnesyltransferase inhibitor">FI</a></i> (<a href="/wiki/Tipifarnib" title="Tipifarnib">Tipifarnib</a><sup>§</sup>)</li> <li><i><a href="/wiki/Cyclin-dependent_kinase" title="Cyclin-dependent kinase">CDK</a> <a href="/wiki/Protein_kinase_inhibitor" title="Protein kinase inhibitor">inhibitors</a></i> (<a href="/wiki/Abemaciclib" title="Abemaciclib">Abemaciclib</a></li> <li><a href="/wiki/Alvocidib" title="Alvocidib">Alvocidib</a><sup>†</sup></li> <li><a href="/wiki/Palbociclib" title="Palbociclib">Palbociclib</a></li> <li><a href="/wiki/Ribociclib" title="Ribociclib">Ribociclib</a></li> <li><a href="/wiki/Seliciclib" title="Seliciclib">Seliciclib</a><sup>†</sup>)</li> <li><i><a href="/wiki/Proteasome_inhibitor" title="Proteasome inhibitor">PrI</a></i> <ul><li><a href="/wiki/Bortezomib" title="Bortezomib">Bortezomib</a></li> <li><a href="/wiki/Carfilzomib" title="Carfilzomib">Carfilzomib</a></li> <li><a href="/wiki/Oprozomib" title="Oprozomib">Oprozomib</a></li> <li><a href="/wiki/Ixazomib" title="Ixazomib">Ixazomib</a></li></ul></li> <li><i><a href="/wiki/Phosphodiesterase_inhibitor" title="Phosphodiesterase inhibitor">PhI</a></i> (<a href="/wiki/Anagrelide" title="Anagrelide">Anagrelide</a>)</li> <li><i><a href="/wiki/IMP_dehydrogenase" class="mw-redirect" title="IMP dehydrogenase">IMPDI</a></i> (<a href="/wiki/Tiazofurin" title="Tiazofurin">Tiazofurin</a><sup>§</sup>)</li> <li><i><a href="/wiki/Lipoxygenase_inhibitor" class="mw-redirect" title="Lipoxygenase inhibitor">LI</a></i> (<a href="/wiki/Masoprocol" title="Masoprocol">Masoprocol</a>)</li> <li><i><a href="/wiki/PARP_inhibitor" title="PARP inhibitor">PARP inhibitor</a></i> (<a href="/wiki/Fuzuloparib" title="Fuzuloparib">Fuzuloparib</a></li> <li><a href="/wiki/Niraparib" title="Niraparib">Niraparib</a> <a href="/wiki/Niraparib/abiraterone_acetate" title="Niraparib/abiraterone acetate">+abiraterone acetate</a></li> <li><a href="/wiki/Olaparib" title="Olaparib">Olaparib</a></li> <li><a href="/wiki/Rucaparib" title="Rucaparib">Rucaparib</a>)</li> <li><i><a href="/wiki/Histone_deacetylase_inhibitor" title="Histone deacetylase inhibitor">HDAC</a></i> (<a href="/wiki/Belinostat" title="Belinostat">Belinostat</a></li> <li><a href="/wiki/Entinostat" title="Entinostat">Entinostat</a></li> <li><a href="/wiki/Panobinostat" title="Panobinostat">Panobinostat</a></li> <li><a href="/wiki/Romidepsin" title="Romidepsin">Romidepsin</a></li> <li><a href="/wiki/Vorinostat" title="Vorinostat">Vorinostat</a>)</li> <li><i><a href="/wiki/Phosphoinositide_3-kinase_inhibitor" title="Phosphoinositide 3-kinase inhibitor">PIKI</a> (Pi3K)</i> (<a href="/wiki/Alpelisib" title="Alpelisib">Alpelisib</a></li> <li><a href="/wiki/Copanlisib" title="Copanlisib">Copanlisib</a><sup>‡</sup></li> <li><a href="/wiki/Duvelisib" title="Duvelisib">Duvelisib</a></li> <li><a href="/wiki/Idelalisib" title="Idelalisib">Idelalisib</a></li> <li><a href="/wiki/Inavolisib" title="Inavolisib">Inavolisib</a></li> <li><a href="/wiki/Umbralisib" title="Umbralisib">Umbralisib</a><sup>‡</sup>)</li> <li><i><a href="/wiki/Isocitrate_dehydrogenase" title="Isocitrate dehydrogenase">IDH</a></i> (<a href="/wiki/Enasidenib" title="Enasidenib">Enasidenib</a></li> <li><a href="/wiki/Ivosidenib" title="Ivosidenib">Ivosidenib</a></li> <li><a href="/wiki/Olutasidenib" title="Olutasidenib">Olutasidenib</a></li> <li><a href="/wiki/Vorasidenib" title="Vorasidenib">Vorasidenib</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Receptor_antagonist" title="Receptor antagonist">Receptor antagonists</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Endothelin_receptor_antagonist" title="Endothelin receptor antagonist">ERA</a></i> (<a href="/wiki/Atrasentan" title="Atrasentan">Atrasentan</a>)</li> <li><i><a href="/wiki/Retinoid_X_receptor" title="Retinoid X receptor">Retinoid X receptor</a></i> (<a href="/wiki/Bexarotene" title="Bexarotene">Bexarotene</a>)</li> <li><i><a href="/wiki/Sex_steroid" class="mw-redirect" title="Sex steroid">Sex steroid</a></i> (<a href="/wiki/Testolactone" title="Testolactone">Testolactone</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other/ungrouped</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adagrasib" title="Adagrasib">Adagrasib</a></li> <li><a href="/wiki/Aflibercept" title="Aflibercept">Aflibercept</a></li> <li><a class="mw-selflink selflink">Arsenic trioxide</a></li> <li><i><a href="/wiki/Asparagine" title="Asparagine">Asparagine depleters</a></i> (<a href="/wiki/Asparaginase" title="Asparaginase">Asparaginase</a><sup>#</sup>/<a href="/wiki/Pegaspargase" title="Pegaspargase">Pegaspargase</a>)</li> <li><a href="/wiki/Axicabtagene_ciloleucel" title="Axicabtagene ciloleucel">Axicabtagene ciloleucel</a></li> <li><a href="/wiki/Belzutifan" title="Belzutifan">Belzutifan</a></li> <li><a href="/wiki/Bexarotene" title="Bexarotene">Bexarotene</a></li> <li><a href="/wiki/Brexucabtagene_autoleucel" title="Brexucabtagene autoleucel">Brexucabtagene autoleucel</a></li> <li><a href="/wiki/Celecoxib" title="Celecoxib">Celecoxib</a></li> <li><a href="/wiki/Ciltacabtagene_autoleucel" title="Ciltacabtagene autoleucel">Ciltacabtagene autoleucel</a></li> <li><a href="/wiki/Demecolcine" title="Demecolcine">Demecolcine</a></li> <li><a href="/wiki/Denileukin_diftitox" title="Denileukin diftitox">Denileukin diftitox</a></li> <li><a href="/wiki/Eflornithine" title="Eflornithine">Eflornithine</a></li> <li><a href="/wiki/Elesclomol" title="Elesclomol">Elesclomol</a><sup>§</sup></li> <li><a href="/wiki/Elsamitrucin" title="Elsamitrucin">Elsamitrucin</a></li> <li><a href="/wiki/Epacadostat" title="Epacadostat">Epacadostat</a></li> <li><a href="/wiki/Eribulin" title="Eribulin">Eribulin</a></li> <li><a href="/wiki/Estramustine_phosphate" title="Estramustine phosphate">Estramustine</a></li> <li><a href="/wiki/Glasdegib" title="Glasdegib">Glasdegib</a></li> <li><a href="/wiki/Idecabtagene_vicleucel" title="Idecabtagene vicleucel">Idecabtagene vicleucel</a></li> <li><a href="/wiki/Imetelstat" title="Imetelstat">Imetelstat</a></li> <li><a href="/wiki/Lifileucel" title="Lifileucel">Lifileucel</a></li> <li><a href="/wiki/Lisocabtagene_maraleucel" title="Lisocabtagene maraleucel">Lisocabtagene maraleucel</a></li> <li><a href="/wiki/Lonidamine" title="Lonidamine">Lonidamine</a></li> <li><a href="/wiki/Lucanthone" title="Lucanthone">Lucanthone</a></li> <li><a href="/wiki/Lurbinectedin" title="Lurbinectedin">Lurbinectedin</a></li> <li><a href="/wiki/Mitoguazone" title="Mitoguazone">Mitoguazone</a></li> <li><a href="/wiki/Mitotane" title="Mitotane">Mitotane</a></li> <li><a href="/wiki/Nadofaragene_firadenovec" title="Nadofaragene firadenovec">Nadofaragene firadenovec</a></li> <li><a href="/wiki/Navitoclax" title="Navitoclax">Navitoclax</a></li> <li><a href="/wiki/Obecabtagene_autoleucel" title="Obecabtagene autoleucel">Obecabtagene autoleucel</a></li> <li><a href="/wiki/Oblimersen" title="Oblimersen">Oblimersen</a><sup>†</sup></li> <li><a href="/wiki/Omacetaxine_mepesuccinate" title="Omacetaxine mepesuccinate">Omacetaxine mepesuccinate</a></li> <li><a href="/wiki/Plitidepsin" title="Plitidepsin">Plitidepsin</a></li> <li><a href="/wiki/Tabelecleucel" title="Tabelecleucel">Tabelecleucel</a></li> <li><i><a href="/wiki/Retinoid" title="Retinoid">Retinoids</a></i> (<a href="/wiki/Alitretinoin" title="Alitretinoin">Alitretinoin</a></li> <li><a href="/wiki/Tretinoin" title="Tretinoin">Tretinoin</a><sup>#</sup>)</li> <li><a href="/wiki/Selinexor" title="Selinexor">Selinexor</a></li> <li><a href="/w/index.php?title=Sitimagene_ceradenovec&action=edit&redlink=1" class="new" title="Sitimagene ceradenovec (page does not exist)">Sitimagene ceradenovec</a></li> <li><a href="/wiki/Sotorasib" title="Sotorasib">Sotorasib</a></li> <li><a href="/wiki/Tagraxofusp" title="Tagraxofusp">Tagraxofusp</a></li> <li><a href="/wiki/Talimogene_laherparepvec" title="Talimogene laherparepvec">Talimogene laherparepvec</a></li> <li><a href="/wiki/Tazemetostat" title="Tazemetostat">Tazemetostat</a></li> <li><a href="/wiki/Tebentafusp" title="Tebentafusp">Tebentafusp</a></li> <li><a href="/wiki/Tiazofurine" class="mw-redirect" title="Tiazofurine">Tiazofurine</a></li> <li><a href="/wiki/Tigilanol_tiglate" title="Tigilanol tiglate">Tigilanol tiglate</a></li> <li><a href="/wiki/Tisagenlecleucel" title="Tisagenlecleucel">Tisagenlecleucel</a></li> <li><a href="/wiki/Trabectedin" title="Trabectedin">Trabectedin</a></li> <li><a href="/wiki/Veliparib" title="Veliparib">Veliparib</a></li> <li><a href="/wiki/Venetoclax" title="Venetoclax">Venetoclax</a></li> <li><a href="/w/index.php?title=Verdinexor&action=edit&redlink=1" class="new" title="Verdinexor (page does not exist)">Verdinexor</a></li> <li><a href="/wiki/Vosaroxin" title="Vosaroxin">Vosaroxin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><link rel="mw-deduplicated-inline-style" 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aria-labelledby="Arsenic_compounds" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Arsenic_compounds" title="Template:Arsenic compounds"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Arsenic_compounds" title="Template talk:Arsenic compounds"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Arsenic_compounds" title="Special:EditPage/Template:Arsenic compounds"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Arsenic_compounds" style="font-size:114%;margin:0 4em"><a href="/wiki/Arsenic" title="Arsenic">Arsenic</a> compounds</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Arsenide" title="Arsenide">Arsenides</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aluminium_arsenide" title="Aluminium arsenide">AlAs</a></li> <li><a href="/wiki/Boron_arsenide" title="Boron arsenide">BAs</a></li> <li><a href="/wiki/Bismuth_arsenide" title="Bismuth arsenide">BiAs</a></li> <li><span class="chemf nowrap"><a href="/wiki/Cadmium_arsenide" title="Cadmium arsenide">Cd<sub class="template-chem2-sub">3</sub>As<sub class="template-chem2-sub">2</sub></a></span></li> <li><a href="/wiki/Calcium_arsenide" title="Calcium arsenide">CaAs</a></li> <li><a href="/wiki/Cobalt_arsenide" title="Cobalt arsenide">CoAs</a></li> <li><a href="/wiki/Dysprosium_arsenide" title="Dysprosium arsenide">DyAs</a></li> <li><span class="chemf nowrap"><a href="/wiki/Holmium_arsenide" title="Holmium arsenide">HoAs</a></span></li> <li><a href="/wiki/Gallium_arsenide" title="Gallium arsenide">GaAs</a></li> <li><a href="/wiki/Indium_arsenide" title="Indium arsenide">InAs</a></li> <li><a href="/wiki/Yttrium(III)_arsenide" title="Yttrium(III) arsenide">YAs</a></li> <li><a href="/wiki/Lithium_arsenide" title="Lithium arsenide">LiAs</a></li> <li><a href="/wiki/Molybdenum_diarsenide" title="Molybdenum diarsenide">MoAs<sub>2</sub></a></li> <li><a href="/wiki/Manganese_arsenide" title="Manganese arsenide">MnAs</a></li> <li><a href="/wiki/Neptunium_arsenide" title="Neptunium arsenide">NpAs</a></li> <li><span class="chemf nowrap"><a href="/wiki/Neptunium_diarsenide" title="Neptunium diarsenide">NpAs<sub class="template-chem2-sub">2</sub></a></span></li> <li><a href="/wiki/Palladium_diarsenide" title="Palladium diarsenide">PdAs<sub>2</sub></a></li> <li><a href="/wiki/Praseodymium_arsenide" title="Praseodymium arsenide">PrAs</a></li> <li><a href="/wiki/Plutonium_arsenide" class="mw-redirect" title="Plutonium arsenide">PuAs</a></li> <li><a href="/wiki/Samarium_arsenide" class="mw-redirect" title="Samarium arsenide">SmAs</a></li> <li><a href="/wiki/Sodium_arsenide" title="Sodium arsenide">Na<sub>3</sub>As</a></li> <li><a href="/wiki/Tantalum_arsenide" title="Tantalum arsenide">TaAs</a></li> <li><a href="/wiki/Tungsten_diarsenide" title="Tungsten diarsenide">WAs<sub>2</sub></a></li> <li><a href="/wiki/Yttrium_arsenide" class="mw-redirect" title="Yttrium arsenide">YAs</a></li> <li><span class="chemf nowrap"><a href="/wiki/Zinc_arsenide" title="Zinc arsenide">Zn<sub class="template-chem2-sub">3</sub>As<sub class="template-chem2-sub">2</sub></a></span></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">As(III)</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arsenic_tribromide" title="Arsenic tribromide">AsBr<sub>3</sub></a></li> <li><a href="/wiki/Arsenic_trichloride" title="Arsenic trichloride">AsCl<sub>3</sub></a></li> <li><a href="/wiki/Arsenic_pentachloride" title="Arsenic pentachloride">AsCl<sub>5</sub></a></li> <li><a href="/wiki/Arsenic_trifluoride" title="Arsenic trifluoride">AsF<sub>3</sub></a></li> <li><a href="/wiki/Arsine" title="Arsine">AsH<sub>3</sub></a></li> <li><a href="/wiki/Arsenic_triiodide" title="Arsenic triiodide">AsI<sub>3</sub></a></li> <li><span class="chemf nowrap"><a class="mw-selflink selflink">As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">3</sub></a></span></li> <li><span class="chemf nowrap"><a href="/wiki/Arsenic_trisulfide" title="Arsenic trisulfide">As<sub class="template-chem2-sub">2</sub>S<sub class="template-chem2-sub">3</sub></a></span></li> <li><span class="chemf nowrap"><a href="/wiki/Arsenic_triselenide" title="Arsenic triselenide">As<sub class="template-chem2-sub">2</sub>Se<sub class="template-chem2-sub">3</sub></a></span></li> <li><span class="chemf nowrap"><a href="/wiki/Realgar" title="Realgar">As<sub class="template-chem2-sub">4</sub>S<sub class="template-chem2-sub">4</sub></a></span></li> <li><span class="chemf nowrap"><a href="/wiki/Arsenic_monophosphide" title="Arsenic monophosphide">AsP</a></span></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">As(III,V)</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><span class="chemf nowrap"><a href="/wiki/Arsenic_tetroxide" title="Arsenic tetroxide">As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">4</sub></a></span></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">As(V)</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arsenic_pentafluoride" title="Arsenic pentafluoride">AsF<sub>5</sub></a></li> <li><a href="/wiki/Arsenic_pentachloride" title="Arsenic pentachloride">AsCl<sub>5</sub></a></li> <li><span class="chemf nowrap"><a href="/wiki/Arsenic_pentoxide" title="Arsenic pentoxide">As<sub class="template-chem2-sub">2</sub>O<sub class="template-chem2-sub">5</sub></a></span></li> <li><span class="chemf nowrap"><a href="/wiki/Arsenic_pentasulfide" title="Arsenic pentasulfide">As<sub class="template-chem2-sub">2</sub>S<sub class="template-chem2-sub">5</sub></a></span></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Oxides" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Oxides" title="Template:Oxides"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Oxides" title="Template talk:Oxides"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Oxides" title="Special:EditPage/Template:Oxides"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Oxides" style="font-size:114%;margin:0 4em"><a href="/wiki/Oxide" title="Oxide">Oxides</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Mixed oxidation states</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Antimony_tetroxide" title="Antimony tetroxide">Antimony tetroxide</a> (<a href="/wiki/Antimony" title="Antimony">Sb</a><sub>2</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Boron_suboxide" title="Boron suboxide">Boron suboxide</a> (<a href="/wiki/Boron" title="Boron">B</a><sub>12</sub>O<sub>2</sub>)</li> <li><a href="/wiki/Carbon_suboxide" title="Carbon suboxide">Carbon suboxide</a> (<a href="/wiki/Carbon" title="Carbon">C</a><sub>3</sub>O<sub>2</sub>)</li> <li><a href="/wiki/Chlorine_perchlorate" title="Chlorine perchlorate">Chlorine perchlorate</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a><sub>2</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Chloryl_perchlorate" class="mw-redirect" title="Chloryl perchlorate">Chloryl perchlorate</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a><sub>2</sub>O<sub>6</sub>)</li> <li><a href="/wiki/Cobalt(II,III)_oxide" title="Cobalt(II,III) oxide">Cobalt(II,III) oxide</a> (<a href="/wiki/Cobalt" title="Cobalt">Co</a><sub>3</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Dichlorine_pentoxide" title="Dichlorine pentoxide">Dichlorine pentoxide</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Iron(II,III)_oxide" title="Iron(II,III) oxide">Iron(II,III) oxide</a> (<a href="/wiki/Iron" title="Iron">Fe</a><sub>3</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Lead(II,IV)_oxide" title="Lead(II,IV) oxide">Lead(II,IV) oxide</a> (<a href="/wiki/Lead" title="Lead">Pb</a><sub>3</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Manganese(II,III)_oxide" title="Manganese(II,III) oxide">Manganese(II,III) oxide</a> (<a href="/wiki/Manganese" title="Manganese">Mn</a><sub>3</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Mellitic_anhydride" title="Mellitic anhydride">Mellitic anhydride</a> (<a href="/wiki/Carbon" title="Carbon">C</a><sub>12</sub>O<sub>9</sub>)</li> <li><a href="/wiki/Praseodymium(III,IV)_oxide" title="Praseodymium(III,IV) oxide">Praseodymium(III,IV) oxide</a> (<a href="/wiki/Praseodymium" title="Praseodymium">Pr</a><sub>6</sub>O<sub>11</sub>)</li> <li><a href="/wiki/Silver(I,III)_oxide" title="Silver(I,III) oxide">Silver(I,III) oxide</a> (<a href="/wiki/Silver" title="Silver">Ag</a><sub>2</sub>O<sub>2</sub>)</li> <li><a href="/wiki/Terbium(III,IV)_oxide" title="Terbium(III,IV) oxide">Terbium(III,IV) oxide</a> (<a href="/wiki/Terbium" title="Terbium">Tb</a><sub>4</sub>O<sub>7</sub>)</li> <li><a href="/wiki/Tribromine_octoxide" title="Tribromine octoxide">Tribromine octoxide</a> (<a href="/wiki/Bromine" title="Bromine">Br</a><sub>3</sub>O<sub>8</sub>)</li> <li><a href="/wiki/Triuranium_octoxide" title="Triuranium octoxide">Triuranium octoxide</a> (<a href="/wiki/Uranium" title="Uranium">U</a><sub>3</sub>O<sub>8</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+1 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aluminium(I)_oxide" title="Aluminium(I) oxide">Aluminium(I) oxide</a> (<a href="/wiki/Aluminium" title="Aluminium">Al</a><sub>2</sub>O)</li> <li><a href="/wiki/Copper(I)_oxide" title="Copper(I) oxide">Copper(I) oxide</a> (<a href="/wiki/Copper" title="Copper">Cu</a><sub>2</sub>O)</li> <li><a href="/wiki/Caesium_monoxide" title="Caesium monoxide">Caesium monoxide</a> (<a href="/wiki/Caesium" title="Caesium">Cs</a><sub>2</sub>O)</li> <li><a href="/wiki/Dibromine_monoxide" title="Dibromine monoxide">Dibromine monoxide</a> (<a href="/wiki/Bromine" title="Bromine">Br</a><sub>2</sub>O)</li> <li><a href="/wiki/Dicarbon_monoxide" title="Dicarbon monoxide">Dicarbon monoxide</a> (<a href="/wiki/Carbon" title="Carbon">C</a><sub>2</sub>O)</li> <li><a href="/wiki/Dichlorine_monoxide" title="Dichlorine monoxide">Dichlorine monoxide</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a><sub>2</sub>O)</li> <li><a href="/wiki/Gallium(I)_oxide" title="Gallium(I) oxide">Gallium(I) oxide</a> (<a href="/wiki/Gallium" title="Gallium">Ga</a><sub>2</sub>O)</li> <li><a href="/wiki/Iodine(I)_oxide" class="mw-redirect" title="Iodine(I) oxide">Iodine(I) oxide</a> (<a href="/wiki/Iodine" title="Iodine">I</a><sub>2</sub>O)</li> <li><a href="/wiki/Lithium_oxide" title="Lithium oxide">Lithium oxide</a> (<a href="/wiki/Lithium" title="Lithium">Li</a><sub>2</sub>O)</li> <li><a href="/wiki/Mercury(I)_oxide" title="Mercury(I) oxide">Mercury(I) oxide</a> (<a href="/wiki/Mercury_(element)" title="Mercury (element)">Hg</a><sub>2</sub>O)</li> <li><a href="/wiki/Nitrous_oxide" title="Nitrous oxide">Nitrous oxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a><sub>2</sub>O)</li> <li><a href="/wiki/Potassium_oxide" title="Potassium oxide">Potassium oxide</a> (<a href="/wiki/Potassium" title="Potassium">K</a><sub>2</sub>O)</li> <li><a href="/wiki/Rubidium_oxide" title="Rubidium oxide">Rubidium oxide</a> (<a href="/wiki/Rubidium" title="Rubidium">Rb</a><sub>2</sub>O)</li> <li><a href="/wiki/Silver_oxide" title="Silver oxide">Silver oxide</a> (<a href="/wiki/Silver" title="Silver">Ag</a><sub>2</sub>O)</li> <li><a href="/wiki/Thallium(I)_oxide" title="Thallium(I) oxide">Thallium(I) oxide</a> (<a href="/wiki/Thallium" title="Thallium">Tl</a><sub>2</sub>O)</li> <li><a href="/wiki/Sodium_oxide" title="Sodium oxide">Sodium oxide</a> (<a href="/wiki/Sodium" title="Sodium">Na</a><sub>2</sub>O)</li> <li><a href="/wiki/Properties_of_water" title="Properties of water">Water (hydrogen oxide)</a> (<a href="/wiki/Hydrogen" title="Hydrogen">H</a><sub>2</sub>O)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+2 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aluminium(II)_oxide" title="Aluminium(II) oxide">Aluminium(II) oxide</a> (<a href="/wiki/Aluminium" title="Aluminium">Al</a>O)</li> <li><a href="/wiki/Barium_oxide" title="Barium oxide">Barium oxide</a> (<a href="/wiki/Barium" title="Barium">Ba</a>O)</li> <li><a href="/wiki/Berkelium_monoxide" class="mw-redirect" title="Berkelium monoxide">Berkelium monoxide</a> (<a href="/wiki/Berkelium" title="Berkelium">Bk</a>O)</li> <li><a href="/wiki/Beryllium_oxide" title="Beryllium oxide">Beryllium oxide</a> (<a href="/wiki/Beryllium" title="Beryllium">Be</a>O)</li> <li><a href="/wiki/Boron_monoxide" title="Boron monoxide">Boron monoxide</a> (<a href="/wiki/Boron" title="Boron">B</a>O)</li> <li><a href="/wiki/Bromine_monoxide" class="mw-redirect" title="Bromine monoxide">Bromine monoxide</a> (<a href="/wiki/Bromine" title="Bromine">Br</a>O)</li> <li><a href="/wiki/Cadmium_oxide" title="Cadmium oxide">Cadmium oxide</a> (<a href="/wiki/Cadmium" title="Cadmium">Cd</a>O)</li> <li><a href="/wiki/Calcium_oxide" title="Calcium oxide">Calcium oxide</a> (<a href="/wiki/Calcium" title="Calcium">Ca</a>O)</li> <li><a href="/wiki/Carbon_monoxide" title="Carbon monoxide">Carbon monoxide</a> (<a href="/wiki/Carbon" title="Carbon">C</a>O)</li> <li><a href="/wiki/Chlorine_monoxide" title="Chlorine monoxide">Chlorine monoxide</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a>O)</li> <li><a href="/wiki/Chromium(II)_oxide" title="Chromium(II) oxide">Chromium(II) oxide</a> (<a href="/wiki/Chromium" title="Chromium">Cr</a>O)</li> <li><a href="/wiki/Cobalt(II)_oxide" title="Cobalt(II) oxide">Cobalt(II) oxide</a> (<a href="/wiki/Cobalt" title="Cobalt">Co</a>O)</li> <li><a href="/wiki/Copper(II)_oxide" title="Copper(II) oxide">Copper(II) oxide</a> (<a href="/wiki/Copper" title="Copper">Cu</a>O)</li> <li><a href="/wiki/Dinitrogen_dioxide" title="Dinitrogen dioxide">Dinitrogen dioxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a><sub>2</sub>O<sub>2</sub>)</li> <li><a href="/wiki/Europium(II)_oxide" title="Europium(II) oxide">Europium(II) oxide</a> (<a href="/wiki/Europium" title="Europium">Eu</a>O)</li> <li><a href="/wiki/Germanium_monoxide" title="Germanium monoxide">Germanium monoxide</a> (<a href="/wiki/Germanium" title="Germanium">Ge</a>O)</li> <li><a href="/wiki/Iron(II)_oxide" title="Iron(II) oxide">Iron(II) oxide</a> (<a href="/wiki/Iron" title="Iron">Fe</a>O)</li> <li><a href="/wiki/Iodine_monoxide" title="Iodine monoxide">Iodine monoxide</a> (<a href="/wiki/Iodine" title="Iodine">I</a>O)</li> <li><a href="/wiki/Lead(II)_oxide" title="Lead(II) oxide">Lead(II) oxide</a> (<a href="/wiki/Lead" title="Lead">Pb</a>O)</li> <li><a href="/wiki/Magnesium_oxide" title="Magnesium oxide">Magnesium oxide</a> (<a href="/wiki/Magnesium" title="Magnesium">Mg</a>O)</li> <li><a href="/wiki/Manganese(II)_oxide" title="Manganese(II) oxide">Manganese(II) oxide</a> (<a href="/wiki/Manganese" title="Manganese">Mn</a>O)</li> <li><a href="/wiki/Mercury(II)_oxide" title="Mercury(II) oxide">Mercury(II) oxide</a> (<a href="/wiki/Mercury_(element)" title="Mercury (element)">Hg</a>O)</li> <li><a href="/wiki/Nickel(II)_oxide" title="Nickel(II) oxide">Nickel(II) oxide</a> (<a href="/wiki/Nickel" title="Nickel">Ni</a>O)</li> <li><a href="/wiki/Nitric_oxide" title="Nitric oxide">Nitric oxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a>O)</li> <li><a href="/wiki/Niobium_monoxide" title="Niobium monoxide">Niobium monoxide</a> (<a href="/wiki/Niobium" title="Niobium">Nb</a>O)</li> <li><a href="/wiki/Palladium(II)_oxide" title="Palladium(II) oxide">Palladium(II) oxide</a> (<a href="/wiki/Palladium" title="Palladium">Pd</a>O)</li> <li><a href="/wiki/Phosphorus_monoxide" title="Phosphorus monoxide">Phosphorus monoxide</a> (<a href="/wiki/Phosphorus" title="Phosphorus">P</a>O)</li> <li><a href="/wiki/Polonium_monoxide" title="Polonium monoxide">Polonium monoxide</a> (<a href="/wiki/Polonium" title="Polonium">Po</a>O)</li> <li><a href="/wiki/Protactinium_monoxide" title="Protactinium monoxide">Protactinium monoxide</a> (<a href="/wiki/Protactinium" title="Protactinium">Pa</a>O)</li> <li><a href="/wiki/Radium_oxide" title="Radium oxide">Radium oxide</a> (<a href="/wiki/Radium" title="Radium">Ra</a>O)</li> <li><a href="/wiki/Silicon_monoxide" title="Silicon monoxide">Silicon monoxide</a> (<a href="/wiki/Silicon" title="Silicon">Si</a>O)</li> <li><a href="/wiki/Strontium_oxide" title="Strontium oxide">Strontium oxide</a> (<a href="/wiki/Strontium" title="Strontium">Sr</a>O)</li> <li><a href="/wiki/Sulfur_monoxide" title="Sulfur monoxide">Sulfur monoxide</a> (<a href="/wiki/Sulfur" title="Sulfur">S</a>O)</li> <li><a href="/wiki/Disulfur_dioxide" title="Disulfur dioxide">Disulfur dioxide</a> (<a href="/wiki/Sulfur" title="Sulfur">S</a><sub>2</sub>O<sub>2</sub>)</li> <li><a href="/wiki/Thorium_monoxide" title="Thorium monoxide">Thorium monoxide</a> (<a href="/wiki/Thorium" title="Thorium">Th</a>O)</li> <li><a href="/wiki/Tin(II)_oxide" title="Tin(II) oxide">Tin(II) oxide</a> (<a href="/wiki/Tin" title="Tin">Sn</a>O)</li> <li><a href="/wiki/Titanium(II)_oxide" title="Titanium(II) oxide">Titanium(II) oxide</a> (<a href="/wiki/Titanium" title="Titanium">Ti</a>O)</li> <li><a href="/wiki/Vanadium(II)_oxide" title="Vanadium(II) oxide">Vanadium(II) oxide</a> (<a href="/wiki/Vanadium" title="Vanadium">V</a>O)</li> <li><a href="/wiki/Yttrium(II)_oxide" title="Yttrium(II) oxide">Yttrium(II) oxide</a> (<a href="/wiki/Yttrium" title="Yttrium">Y</a>O)</li> <li><a href="/wiki/Zirconium_monoxide" class="mw-redirect" title="Zirconium monoxide">Zirconium monoxide</a> (<a href="/wiki/Zirconium" title="Zirconium">Zr</a>O)</li> <li><a href="/wiki/Zinc_oxide" title="Zinc oxide">Zinc oxide</a> (<a href="/wiki/Zinc" title="Zinc">Zn</a>O)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+3 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Actinium(III)_oxide" title="Actinium(III) oxide">Actinium(III) oxide</a> (<a href="/wiki/Actinium" title="Actinium">Ac</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Aluminium_oxide" title="Aluminium oxide">Aluminium oxide</a> (<a href="/wiki/Aluminium" title="Aluminium">Al</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Americium(III)_oxide" title="Americium(III) oxide">Americium(III) oxide</a> (<a href="/wiki/Americium" title="Americium">Am</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Antimony_trioxide" title="Antimony trioxide">Antimony trioxide</a> (<a href="/wiki/Antimony" title="Antimony">Sb</a><sub>2</sub>O<sub>3</sub>)</li> <li><a class="mw-selflink selflink">Arsenic trioxide</a> (<a href="/wiki/Arsenic" title="Arsenic">As</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Berkelium(III)_oxide" title="Berkelium(III) oxide">Berkelium(III) oxide</a> (<a href="/wiki/Berkelium" title="Berkelium">Bk</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Bismuth(III)_oxide" title="Bismuth(III) oxide">Bismuth(III) oxide</a> (<a href="/wiki/Bismuth" title="Bismuth">Bi</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Boron_trioxide" title="Boron trioxide">Boron trioxide</a> (<a href="/wiki/Boron" title="Boron">B</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Caesium_sesquioxide" title="Caesium sesquioxide">Caesium sesquioxide</a> (<a href="/wiki/Caesium" title="Caesium">Cs</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Californium(III)_oxide" title="Californium(III) oxide">Californium(III) oxide</a> (<a href="/wiki/Californium" title="Californium">Cf</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Cerium(III)_oxide" title="Cerium(III) oxide">Cerium(III) oxide</a> (<a href="/wiki/Cerium" title="Cerium">Ce</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Chromium(III)_oxide" title="Chromium(III) oxide">Chromium(III) oxide</a> (<a href="/wiki/Chromium" title="Chromium">Cr</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Cobalt(III)_oxide" title="Cobalt(III) oxide">Cobalt(III) oxide</a> (<a href="/wiki/Cobalt" title="Cobalt">Co</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Dinitrogen_trioxide" title="Dinitrogen trioxide">Dinitrogen trioxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Dysprosium(III)_oxide" title="Dysprosium(III) oxide">Dysprosium(III) oxide</a> (<a href="/wiki/Dysprosium" title="Dysprosium">Dy</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Einsteinium(III)_oxide" title="Einsteinium(III) oxide">Einsteinium(III) oxide</a> (<a href="/wiki/Einsteinium" title="Einsteinium">Es</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Erbium(III)_oxide" title="Erbium(III) oxide">Erbium(III) oxide</a> (<a href="/wiki/Erbium" title="Erbium">Er</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Europium(III)_oxide" title="Europium(III) oxide">Europium(III) oxide</a> (<a href="/wiki/Europium" title="Europium">Eu</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Gadolinium(III)_oxide" title="Gadolinium(III) oxide">Gadolinium(III) oxide</a> (<a href="/wiki/Gadolinium" title="Gadolinium">Gd</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Gallium(III)_oxide" title="Gallium(III) oxide">Gallium(III) oxide</a> (<a href="/wiki/Gallium" title="Gallium">Ga</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Gold(III)_oxide" title="Gold(III) oxide">Gold(III) oxide</a> (<a href="/wiki/Gold" title="Gold">Au</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Holmium(III)_oxide" title="Holmium(III) oxide">Holmium(III) oxide</a> (<a href="/wiki/Holmium" title="Holmium">Ho</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Indium(III)_oxide" title="Indium(III) oxide">Indium(III) oxide</a> (<a href="/wiki/Indium" title="Indium">In</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Iron(III)_oxide" title="Iron(III) oxide">Iron(III) oxide</a> (<a href="/wiki/Iron" title="Iron">Fe</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Lanthanum_oxide" title="Lanthanum oxide">Lanthanum oxide</a> (<a href="/wiki/Lanthanum" title="Lanthanum">La</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Lutetium(III)_oxide" title="Lutetium(III) oxide">Lutetium(III) oxide</a> (<a href="/wiki/Lutetium" title="Lutetium">Lu</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Manganese(III)_oxide" title="Manganese(III) oxide">Manganese(III) oxide</a> (<a href="/wiki/Manganese" title="Manganese">Mn</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Neodymium(III)_oxide" title="Neodymium(III) oxide">Neodymium(III) oxide</a> (<a href="/wiki/Neodymium" title="Neodymium">Nd</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Nickel(III)_oxide" title="Nickel(III) oxide">Nickel(III) oxide</a> (<a href="/wiki/Nickel" title="Nickel">Ni</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Phosphorus_trioxide" title="Phosphorus trioxide">Phosphorus trioxide</a> (<a href="/wiki/Phosphorus" title="Phosphorus">P</a><sub>4</sub>O<sub>6</sub>)</li> <li><a href="/wiki/Praseodymium(III)_oxide" title="Praseodymium(III) oxide">Praseodymium(III) oxide</a> (<a href="/wiki/Praseodymium" title="Praseodymium">Pr</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Promethium(III)_oxide" title="Promethium(III) oxide">Promethium(III) oxide</a> (<a href="/wiki/Promethium" title="Promethium">Pm</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Rhodium(III)_oxide" title="Rhodium(III) oxide">Rhodium(III) oxide</a> (<a href="/wiki/Rhodium" title="Rhodium">Rh</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Samarium(III)_oxide" title="Samarium(III) oxide">Samarium(III) oxide</a> (<a href="/wiki/Samarium" title="Samarium">Sm</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Scandium_oxide" title="Scandium oxide">Scandium oxide</a> (<a href="/wiki/Scandium" title="Scandium">Sc</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Terbium(III)_oxide" title="Terbium(III) oxide">Terbium(III) oxide</a> (<a href="/wiki/Terbium" title="Terbium">Tb</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Thallium(III)_oxide" title="Thallium(III) oxide">Thallium(III) oxide</a> (<a href="/wiki/Thallium" title="Thallium">Tl</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Thulium(III)_oxide" title="Thulium(III) oxide">Thulium(III) oxide</a> (<a href="/wiki/Thulium" title="Thulium">Tm</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Titanium(III)_oxide" title="Titanium(III) oxide">Titanium(III) oxide</a> (<a href="/wiki/Titanium" title="Titanium">Ti</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Tungsten(III)_oxide" title="Tungsten(III) oxide">Tungsten(III) oxide</a> (<a href="/wiki/Tungsten" title="Tungsten">W</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Vanadium(III)_oxide" title="Vanadium(III) oxide">Vanadium(III) oxide</a> (<a href="/wiki/Vanadium" title="Vanadium">V</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Ytterbium(III)_oxide" title="Ytterbium(III) oxide">Ytterbium(III) oxide</a> (<a href="/wiki/Ytterbium" title="Ytterbium">Yb</a><sub>2</sub>O<sub>3</sub>)</li> <li><a href="/wiki/Yttrium(III)_oxide" title="Yttrium(III) oxide">Yttrium(III) oxide</a> (<a href="/wiki/Yttrium" title="Yttrium">Y</a><sub>2</sub>O<sub>3</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+4 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Americium_dioxide" title="Americium dioxide">Americium dioxide</a> (<a href="/wiki/Americium" title="Americium">Am</a>O<sub>2</sub>)</li> <li><a href="/wiki/Berkelium(IV)_oxide" title="Berkelium(IV) oxide">Berkelium(IV) oxide</a> (<a href="/wiki/Berkelium" title="Berkelium">Bk</a>O<sub>2</sub>)</li> <li><a href="/wiki/Bromine_dioxide" title="Bromine dioxide">Bromine dioxide</a> (<a href="/wiki/Bromine" title="Bromine">Br</a>O<sub>2</sub>)</li> <li><a href="/wiki/Californium_dioxide" class="mw-redirect" title="Californium dioxide">Californium dioxide</a> (<a href="/wiki/Californium" title="Californium">Cf</a>O<sub>2</sub>)</li> <li><a href="/wiki/Carbon_dioxide" title="Carbon dioxide">Carbon dioxide</a> (<a href="/wiki/Carbon" title="Carbon">C</a>O<sub>2</sub>)</li> <li><a href="/wiki/Carbon_trioxide" title="Carbon trioxide">Carbon trioxide</a> (<a href="/wiki/Carbon" title="Carbon">C</a>O<sub>3</sub>)</li> <li><a href="/wiki/Cerium(IV)_oxide" title="Cerium(IV) oxide">Cerium(IV) oxide</a> (<a href="/wiki/Cerium" title="Cerium">Ce</a>O<sub>2</sub>)</li> <li><a href="/wiki/Chlorine_dioxide" title="Chlorine dioxide">Chlorine dioxide</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a>O<sub>2</sub>)</li> <li><a href="/wiki/Chromium(IV)_oxide" title="Chromium(IV) oxide">Chromium(IV) oxide</a> (<a href="/wiki/Chromium" title="Chromium">Cr</a>O<sub>2</sub>)</li> <li><a href="/wiki/Curium(IV)_oxide" title="Curium(IV) oxide">Curium(IV) oxide</a> (<a href="/wiki/Curium" title="Curium">Cm</a>O<sub>2</sub>)</li> <li><a href="/wiki/Dinitrogen_tetroxide" title="Dinitrogen tetroxide">Dinitrogen tetroxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a><sub>2</sub>O<sub>4</sub>)</li> <li><a href="/wiki/Germanium_dioxide" title="Germanium dioxide">Germanium dioxide</a> (<a href="/wiki/Germanium" title="Germanium">Ge</a>O<sub>2</sub>)</li> <li><a href="/wiki/Iodine_dioxide" title="Iodine dioxide">Iodine dioxide</a> (<a href="/wiki/Iodine" title="Iodine">I</a>O<sub>2</sub>)</li> <li><a href="/wiki/Iridium_dioxide" class="mw-redirect" title="Iridium dioxide">Iridium dioxide</a> (<a href="/wiki/Iridium" title="Iridium">Ir</a>O<sub>2</sub>)</li> <li><a href="/wiki/Hafnium(IV)_oxide" title="Hafnium(IV) oxide">Hafnium(IV) oxide</a> (<a href="/wiki/Hafnium" title="Hafnium">Hf</a>O<sub>2</sub>)</li> <li><a href="/wiki/Lead_dioxide" title="Lead dioxide">Lead dioxide</a> (<a href="/wiki/Lead" title="Lead">Pb</a>O<sub>2</sub>)</li> <li><a href="/wiki/Manganese_dioxide" title="Manganese dioxide">Manganese dioxide</a> (<a href="/wiki/Manganese" title="Manganese">Mn</a>O<sub>2</sub>)</li> <li><a href="/wiki/Molybdenum_dioxide" title="Molybdenum dioxide">Molybdenum dioxide</a> (<a href="/wiki/Molybdenum" title="Molybdenum">Mo</a>O<sub>2</sub>)</li> <li><a href="/wiki/Neptunium(IV)_oxide" title="Neptunium(IV) oxide">Neptunium(IV) oxide</a> (<a href="/wiki/Neptunium" title="Neptunium">Np</a>O<sub>2</sub>)</li> <li><a href="/wiki/Nitrogen_dioxide" title="Nitrogen dioxide">Nitrogen dioxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a>O<sub>2</sub>)</li> <li><a href="/wiki/Niobium_dioxide" title="Niobium dioxide">Niobium dioxide</a> (<a href="/wiki/Niobium" title="Niobium">Nb</a>O<sub>2</sub>)</li> <li><a href="/wiki/Osmium_dioxide" title="Osmium dioxide">Osmium dioxide</a> (<a href="/wiki/Osmium" title="Osmium">Os</a>O<sub>2</sub>)</li> <li><a href="/wiki/Platinum_dioxide" class="mw-redirect" title="Platinum dioxide">Platinum dioxide</a> (<a href="/wiki/Platinum" title="Platinum">Pt</a>O<sub>2</sub>)</li> <li><a href="/wiki/Plutonium(IV)_oxide" title="Plutonium(IV) oxide">Plutonium(IV) oxide</a> (<a href="/wiki/Plutonium" title="Plutonium">Pu</a>O<sub>2</sub>)</li> <li><a href="/wiki/Polonium_dioxide" title="Polonium dioxide">Polonium dioxide</a> (<a href="/wiki/Polonium" title="Polonium">Po</a>O<sub>2</sub>)</li> <li><a href="/wiki/Praseodymium(IV)_oxide" title="Praseodymium(IV) oxide">Praseodymium(IV) oxide</a> (<a href="/wiki/Praseodymium" title="Praseodymium">Pr</a>O<sub>2</sub>)</li> <li><a href="/wiki/Protactinium(IV)_oxide" title="Protactinium(IV) oxide">Protactinium(IV) oxide</a> (<a href="/wiki/Protactinium" title="Protactinium">Pa</a>O<sub>2</sub>)</li> <li><a href="/wiki/Rhenium(IV)_oxide" title="Rhenium(IV) oxide">Rhenium(IV) oxide</a> (<a href="/wiki/Rhenium" title="Rhenium">Re</a>O<sub>2</sub>)</li> <li><a href="/wiki/Rhodium(IV)_oxide" title="Rhodium(IV) oxide">Rhodium(IV) oxide</a> (<a href="/wiki/Rhodium" title="Rhodium">Rh</a>O<sub>2</sub>)</li> <li><a href="/wiki/Ruthenium(IV)_oxide" title="Ruthenium(IV) oxide">Ruthenium(IV) oxide</a> (<a href="/wiki/Ruthenium" title="Ruthenium">Ru</a>O<sub>2</sub>)</li> <li><a href="/wiki/Selenium_dioxide" title="Selenium dioxide">Selenium dioxide</a> (<a href="/wiki/Selenium" title="Selenium">Se</a>O<sub>2</sub>)</li> <li><a href="/wiki/Silicon_dioxide" title="Silicon dioxide">Silicon dioxide</a> (<a href="/wiki/Silicon" title="Silicon">Si</a>O<sub>2</sub>)</li> <li><a href="/wiki/Sulfur_dioxide" title="Sulfur dioxide">Sulfur dioxide</a> (<a href="/wiki/Sulfur" title="Sulfur">S</a>O<sub>2</sub>)</li> <li><a href="/wiki/Technetium(IV)_oxide" title="Technetium(IV) oxide">Technetium(IV) oxide</a> (<a href="/wiki/Technetium" title="Technetium">Tc</a>O<sub>2</sub>)</li> <li><a href="/wiki/Tellurium_dioxide" title="Tellurium dioxide">Tellurium dioxide</a> (<a href="/wiki/Tellurium" title="Tellurium">Te</a>O<sub>2</sub>)</li> <li><a href="/wiki/Terbium(IV)_oxide" title="Terbium(IV) oxide">Terbium(IV) oxide</a> (<a href="/wiki/Terbium" title="Terbium">Tb</a>O<sub>2</sub>)</li> <li><a href="/wiki/Thorium_dioxide" title="Thorium dioxide">Thorium dioxide</a> (<a href="/wiki/Thorium" title="Thorium">Th</a>O<sub>2</sub>)</li> <li><a href="/wiki/Tin(IV)_oxide" title="Tin(IV) oxide">Tin dioxide</a> (<a href="/wiki/Tin" title="Tin">Sn</a>O<sub>2</sub>)</li> <li><a href="/wiki/Titanium_dioxide" title="Titanium dioxide">Titanium dioxide</a> (<a href="/wiki/Titanium" title="Titanium">Ti</a>O<sub>2</sub>)</li> <li><a href="/wiki/Tungsten(IV)_oxide" title="Tungsten(IV) oxide">Tungsten(IV) oxide</a> (<a href="/wiki/Tungsten" title="Tungsten">W</a>O<sub>2</sub>)</li> <li><a href="/wiki/Uranium_dioxide" title="Uranium dioxide">Uranium dioxide</a> (<a href="/wiki/Uranium" title="Uranium">U</a>O<sub>2</sub>)</li> <li><a href="/wiki/Vanadium(IV)_oxide" title="Vanadium(IV) oxide">Vanadium(IV) oxide</a> (<a href="/wiki/Vanadium" title="Vanadium">V</a>O<sub>2</sub>)</li> <li><a href="/wiki/Zirconium_dioxide" title="Zirconium dioxide">Zirconium dioxide</a> (<a href="/wiki/Zirconium" title="Zirconium">Zr</a>O<sub>2</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+5 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Antimony_pentoxide" title="Antimony pentoxide">Antimony pentoxide</a> (<a href="/wiki/Antimony" title="Antimony">Sb</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Arsenic_pentoxide" title="Arsenic pentoxide">Arsenic pentoxide</a> (<a href="/wiki/Arsenic" title="Arsenic">As</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Bismuth_pentoxide" title="Bismuth pentoxide">Bismuth pentoxide</a> (<a href="/wiki/Bismuth" title="Bismuth">Bi</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Dinitrogen_pentoxide" title="Dinitrogen pentoxide">Dinitrogen pentoxide</a> (<a href="/wiki/Nitrogen" title="Nitrogen">N</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Niobium_pentoxide" title="Niobium pentoxide">Niobium pentoxide</a> (<a href="/wiki/Niobium" title="Niobium">Nb</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Phosphorus_pentoxide" title="Phosphorus pentoxide">Phosphorus pentoxide</a> (<a href="/wiki/Phosphorus" title="Phosphorus">P</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Protactinium(V)_oxide" title="Protactinium(V) oxide">Protactinium(V) oxide</a> (<a href="/wiki/Protactinium" title="Protactinium">Pa</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Tantalum_pentoxide" title="Tantalum pentoxide">Tantalum pentoxide</a> (<a href="/wiki/Tantalum" title="Tantalum">Ta</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Tungsten_pentoxide" title="Tungsten pentoxide">Tungsten pentoxide</a> (<a href="/wiki/Tungsten" title="Tungsten">W</a><sub>2</sub>O<sub>5</sub>)</li> <li><a href="/wiki/Vanadium(V)_oxide" title="Vanadium(V) oxide">Vanadium(V) oxide</a> (<a href="/wiki/Vanadium" title="Vanadium">V</a><sub>2</sub>O<sub>5</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+6 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Chromium_trioxide" title="Chromium trioxide">Chromium trioxide</a> (<a href="/wiki/Chromium" title="Chromium">Cr</a>O<sub>3</sub>)</li> <li><a href="/wiki/Molybdenum_trioxide" title="Molybdenum trioxide">Molybdenum trioxide</a> (<a href="/wiki/Molybdenum" title="Molybdenum">Mo</a>O<sub>3</sub>)</li> <li><a href="/wiki/Polonium_trioxide" title="Polonium trioxide">Polonium trioxide</a> (<a href="/wiki/Polonium" title="Polonium">Po</a>O<sub>3</sub>)</li> <li><a href="/wiki/Rhenium_trioxide" title="Rhenium trioxide">Rhenium trioxide</a> (<a href="/wiki/Rhenium" title="Rhenium">Re</a>O<sub>3</sub>)</li> <li><a href="/wiki/Selenium_trioxide" title="Selenium trioxide">Selenium trioxide</a> (<a href="/wiki/Selenium" title="Selenium">Se</a>O<sub>3</sub>)</li> <li><a href="/wiki/Sulfur_trioxide" title="Sulfur trioxide">Sulfur trioxide</a> (<a href="/wiki/Sulfur" title="Sulfur">S</a>O<sub>3</sub>)</li> <li><a href="/wiki/Tellurium_trioxide" title="Tellurium trioxide">Tellurium trioxide</a> (<a href="/wiki/Tellurium" title="Tellurium">Te</a>O<sub>3</sub>)</li> <li><a href="/wiki/Tungsten_trioxide" title="Tungsten trioxide">Tungsten trioxide</a> (<a href="/wiki/Tungsten" title="Tungsten">W</a>O<sub>3</sub>)</li> <li><a href="/wiki/Uranium_trioxide" title="Uranium trioxide">Uranium trioxide</a> (<a href="/wiki/Uranium" title="Uranium">U</a>O<sub>3</sub>)</li> <li><a href="/wiki/Xenon_trioxide" title="Xenon trioxide">Xenon trioxide</a> (<a href="/wiki/Xenon" title="Xenon">Xe</a>O<sub>3</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+7 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Dichlorine_heptoxide" title="Dichlorine heptoxide">Dichlorine heptoxide</a> (<a href="/wiki/Chlorine" title="Chlorine">Cl</a><sub>2</sub>O<sub>7</sub>)</li> <li><a href="/wiki/Manganese_heptoxide" title="Manganese heptoxide">Manganese heptoxide</a> (<a href="/wiki/Manganese" title="Manganese">Mn</a><sub>2</sub>O<sub>7</sub>)</li> <li><a href="/wiki/Rhenium(VII)_oxide" title="Rhenium(VII) oxide">Rhenium(VII) oxide</a> (<a href="/wiki/Rhenium" title="Rhenium">Re</a><sub>2</sub>O<sub>7</sub>)</li> <li><a href="/wiki/Technetium(VII)_oxide" title="Technetium(VII) oxide">Technetium(VII) oxide</a> (<a href="/wiki/Technetium" title="Technetium">Tc</a><sub>2</sub>O<sub>7</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">+8 oxidation state</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Iridium_tetroxide" title="Iridium tetroxide">Iridium tetroxide</a> (<a href="/wiki/Iridium" title="Iridium">Ir</a>O<sub>4</sub>)</li> <li><a href="/wiki/Osmium_tetroxide" title="Osmium tetroxide">Osmium tetroxide</a> (<a href="/wiki/Osmium" title="Osmium">Os</a>O<sub>4</sub>)</li> <li><a href="/wiki/Ruthenium_tetroxide" title="Ruthenium tetroxide">Ruthenium tetroxide</a> (<a href="/wiki/Ruthenium" title="Ruthenium">Ru</a>O<sub>4</sub>)</li> <li><a href="/wiki/Xenon_tetroxide" title="Xenon tetroxide">Xenon tetroxide</a> (<a href="/wiki/Xenon" title="Xenon">Xe</a>O<sub>4</sub>)</li> <li><a href="/wiki/Hassium_tetroxide" title="Hassium tetroxide">Hassium tetroxide</a> (<a href="/wiki/Hassium" title="Hassium">Hs</a>O<sub>4</sub>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Related</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Oxocarbon" title="Oxocarbon">Oxocarbon</a></li> <li><a href="/wiki/Suboxide" title="Suboxide">Suboxide</a></li> <li><a href="/wiki/Oxyanion" title="Oxyanion">Oxyanion</a></li> <li><a href="/wiki/Ozonide" title="Ozonide">Ozonide</a></li> <li><a href="/wiki/Peroxide" title="Peroxide">Peroxide</a></li> <li><a href="/wiki/Superoxide" title="Superoxide">Superoxide</a></li> <li><a href="/wiki/Oxypnictide" title="Oxypnictide">Oxypnictide</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div>Oxides are sorted by <a href="/wiki/Oxidation_state" title="Oxidation state">oxidation state</a>. 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