CINXE.COM

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In mice (ob/ob) and humans, inactivating mutations of the OB gene can cause obesity.<span class="text_more collapsed"> Leptin signals through the transmembrane Leptin R in the hypothalamus but can also bind shorter and soluble forms of Leptin R which do not signal. Adipocytes increase Leptin expression as cell size increases, resulting in depressed appetite and increased energy expenditure. Low Leptin levels prompt increased appetite and decreased energy expenditure. Leptin can also block the onset of puberty or menses during starvation, extreme exercise-induced weight loss, anorexia, or cancer-induced cachexia.</p> </span></p> <div class="cnsp-show-more-wrapper"><div class="cnsp-show-more collapsed">Show More</div></div> </div></div> <div class="search_header"> "<span class="search_term">Leptin/OB</span>" has 5 results in Products. </div> <div class="search_type"> Sort by: <div class="select_wrapper"><select id="search_type_select">'; <option value="/target/leptin-ob?category=Luminex%20Assays&sort=ranking,desc" selected="selected"> Best Match </option> <option value="/target/leptin-ob?category=Luminex%20Assays&sort=product_title,asc"> Products (A-Z) </option> <option value="/target/leptin-ob?category=Luminex%20Assays&sort=product_added,desc"> Newest </option> <option value="/target/leptin-ob?category=Luminex%20Assays&sort=stars,desc"> Rating </option> </select></div>  </div>  </div>  <div class="cnsp-result search_result search_product"> <h2><a 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Earn double rewards for reviews </div> <div class="cnsp_content"> <div class="cnsp_table"> <div class="cnsp_table_row"> <div class="cnsp_meta"> <div class="cnsp_catnum"><a href="/products/human-obesity-premixed-magnetic-luminex-performance-assay-kit_fcstm08">FCSTM08</a></div> <div class="cnsp_citations"><a href="/products/human-obesity-premixed-magnetic-luminex-performance-assay-kit_fcstm08#product-citations">1 Citation</a></div> <a data-toggle="lightbox" data-gallery="FCSTM08" data-title="Human Obesity Luminex Panel Standard Curves" href="https://resources.rndsystems.com/images/datasheets/fcstm08_human-obesity-premixed-mag-luminex-performance-assay-kit-18112020132744.png"><div class="cnsp_images">2 Images</div></a> <a data-toggle="lightbox" data-gallery="FCSTM08" data-title="Human Obesity Premixed Magnetic Luminex Performance Assay Kit" href="https://resources.rndsystems.com/images/datasheets/fcstm08_human-obesity-premixed-mag-luminex-performance-assay-kit-2872020162732.jpg"></a> <div 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data-variant="FCSTM25,FCSTM25-01,FCSTM25-02,FCSTM25-03,FCSTM25-04,FCSTM25-05,FCSTM25-06,FCSTM25-07,FCSTM25-08,FCSTM25-09,FCSTM25-10,FCSTM25-11,FCSTM25-12,FCSTM25-13,FCSTM25-14,FCSTM25-15,FCSTM25-16,FCSTM25-17,FCSTM25-18,FCSTM25-19,FCSTM25-20,FCSTM25-21,FCSTM25-22,FCSTM25-23,FCSTM25-24,FCSTM25-25,FCSTM25-26,FCSTM25-27,FCSTM25-28" data-search_type="target_search" data-position="5" data-brand="rnd" data-name="Human Tumor Biomarker Luminex庐 Performance Assay" data-category="Luminex Assays" data-sub_category="Luminex High Performance Human Tumor Biomarker Panel - NEW" data-sub_category_id="191" data-price="915" data-currency_code="USD">Human Tumor Biomarker Luminex庐 Performance Assay</a> <span class="new-feature"></span></h2> <div class="cnsp-description"> </div> <div class="cnsp_content"> <div class="cnsp_table"> <div class="cnsp_table_row"> <div class="cnsp_meta"> <div class="cnsp_catnum"><a href="/products/human-tumor-biomarker-luminex-performance-assay_fcstm25">FCSTM25</a></div> <div 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