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class="vector-toc-numb">5</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span 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class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"><span class="mw-redirectedfrom">(Redirected from <a href="/w/index.php?title=Z-disk-associated_protein&redirect=no" class="mw-redirect" title="Z-disk-associated protein">Z-disk-associated protein</a>)</span></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Protein-coding gene in the species Homo sapiens</div> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">LDB3</th></tr><tr><td colspan="4" style="text-align:center"><span typeof="mw:File"><a href="/wiki/File:Protein_LDB3_PDB_1rgw.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d3/Protein_LDB3_PDB_1rgw.png/250px-Protein_LDB3_PDB_1rgw.png" decoding="async" width="250" height="187" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d3/Protein_LDB3_PDB_1rgw.png/375px-Protein_LDB3_PDB_1rgw.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d3/Protein_LDB3_PDB_1rgw.png/500px-Protein_LDB3_PDB_1rgw.png 2x" data-file-width="761" data-file-height="570" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Available structures</th></tr><tr><th rowspan="2" style="background-color:#c3fdb8;width:43px"><a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a></th><td colspan="2" style="background-color:#eee">Ortholog search: <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term=Q9JKS4%20or%20O75112">PDBe</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_name:UniProt%20AND%20rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_accession:Q9JKS4,O75112">RCSB</a> </span></td></tr><tr><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr style="background-color:#ddd;text-align:center"><th colspan="2">List of PDB id codes</th></tr><tr><td colspan="2" style="background-color:#eee"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/4YDP">4YDP</a></span></p></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifiers</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/15710">LDB3</a></span>, CMD1C, CMPD3, CYPHER, LDB3Z1, LDB3Z4, LVNC3, MFM4, ORACLE, PDLIM6, ZASP, CMH24, LIM domain binding 3</td></tr><tr><th scope="row" style="background-color:#c3fdb8">External IDs</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/605906">605906</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:1344412">1344412</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=134626">134626</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=LDB3">LDB3</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000122367">LDB3 - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_10.svg" class="mw-file-description" title="Chromosome 10 (human)"><img alt="Chromosome 10 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/300px-Ideogram_human_chromosome_10.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/450px-Ideogram_human_chromosome_10.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/600px-Ideogram_human_chromosome_10.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Chromosome_10_(human)" class="mw-redirect" title="Chromosome 10 (human)">Chromosome 10 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_10_ideogram.svg" class="mw-file-description" title="Chromosome 10 (human)"><img alt="Chromosome 10 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Human_chromosome_10_ideogram.svg/300px-Human_chromosome_10_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Human_chromosome_10_ideogram.svg/450px-Human_chromosome_10_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Human_chromosome_10_ideogram.svg/600px-Human_chromosome_10_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 185.19985034148px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for LDB3"><img alt="Genomic location for LDB3" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 191.2px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for LDB3"><img alt="Genomic location for LDB3" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">10q23.2</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">86,666,785 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">86,736,072 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_14.svg" class="mw-file-description" title="Chromosome 14 (mouse)"><img alt="Chromosome 14 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Ideogram_house_mouse_chromosome_14.svg/260px-Ideogram_house_mouse_chromosome_14.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Ideogram_house_mouse_chromosome_14.svg/390px-Ideogram_house_mouse_chromosome_14.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Ideogram_house_mouse_chromosome_14.svg/520px-Ideogram_house_mouse_chromosome_14.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks">Chromosome 14 (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_14.svg" class="mw-file-description" title="Chromosome 14 (mouse)"><img alt="Chromosome 14 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Ideogram_of_house_mouse_chromosome_14.svg/300px-Ideogram_of_house_mouse_chromosome_14.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Ideogram_of_house_mouse_chromosome_14.svg/450px-Ideogram_of_house_mouse_chromosome_14.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Ideogram_of_house_mouse_chromosome_14.svg/600px-Ideogram_of_house_mouse_chromosome_14.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 75.325277406973px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for LDB3"><img alt="Genomic location for LDB3" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 81.3px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for LDB3"><img alt="Genomic location for LDB3" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">14|14 B</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">34,248,560 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">34,310,639 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000122367">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">Skeletal muscle tissue of biceps brachii</li><br /><li style="line-height: 137%;">muscle of thigh</li><br /><li style="line-height: 137%;">apex of heart</li><br /><li style="line-height: 137%;">body of tongue</li><br /><li style="line-height: 137%;">vastus lateralis muscle</li><br /><li style="line-height: 137%;">Skeletal muscle tissue of rectus abdominis</li><br /><li style="line-height: 137%;">left ventricle</li><br /><li style="line-height: 137%;">vena cava</li><br /><li style="line-height: 137%;">myocardium of left ventricle</li><br /><li style="line-height: 137%;">atrium</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000021798">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">triceps brachii muscle</li><br /><li style="line-height: 137%;">muscle of thigh</li><br /><li style="line-height: 137%;">medial head of gastrocnemius muscle</li><br /><li style="line-height: 137%;">temporal muscle</li><br /><li style="line-height: 137%;">sternocleidomastoid muscle</li><br /><li style="line-height: 137%;">ankle</li><br /><li style="line-height: 137%;">quadriceps femoris muscle</li><br /><li style="line-height: 137%;">tibialis anterior muscle</li><br /><li style="line-height: 137%;">digastric muscle</li><br /><li style="line-height: 137%;">vastus lateralis muscle</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000122367">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_LDB3_213717_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/PBB_GE_LDB3_213717_at_fs.png/250px-PBB_GE_LDB3_213717_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/PBB_GE_LDB3_213717_at_fs.png/375px-PBB_GE_LDB3_213717_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/08/PBB_GE_LDB3_213717_at_fs.png/500px-PBB_GE_LDB3_213717_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span><br /><br /><span typeof="mw:File"><a href="/wiki/File:PBB_GE_LDB3_216887_s_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/PBB_GE_LDB3_216887_s_at_fs.png/250px-PBB_GE_LDB3_216887_s_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/PBB_GE_LDB3_216887_s_at_fs.png/375px-PBB_GE_LDB3_216887_s_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f2/PBB_GE_LDB3_216887_s_at_fs.png/500px-PBB_GE_LDB3_216887_s_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span><br /><br /><span typeof="mw:File"><a href="/wiki/File:PBB_GE_LDB3_213371_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/PBB_GE_LDB3_213371_at_fs.png/250px-PBB_GE_LDB3_213371_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/PBB_GE_LDB3_213371_at_fs.png/375px-PBB_GE_LDB3_213371_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/PBB_GE_LDB3_213371_at_fs.png/500px-PBB_GE_LDB3_213371_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/11155/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Molecular function</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008092">cytoskeletal protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515">protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046872">metal ion binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0051371">muscle alpha-actinin binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005080">protein kinase C binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0003779">actin binding</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Cellular component</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005737">cytoplasm</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0048471">perinuclear region of cytoplasm</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042995">cell projection</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031143">pseudopodium</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030018">Z discdkac</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005856">cytoskeleton</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001725">stress fiber</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031941">filamentous actin</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Biological process</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045214">sarcomere organization</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007507">heart development</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030036">actin cytoskeleton organization</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0061061">muscle structure development</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=11155&rn=1">11155</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=24131&rn=1">24131</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000122367;db=core">ENSG00000122367</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000021798;db=core">ENSMUSG00000021798</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/O75112">O75112</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q9JKS4">Q9JKS4</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNA)</th><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001080114">NM_001080114</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001080115">NM_001080115</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001080116">NM_001080116</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001171610">NM_001171610</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001171611">NM_001171611</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_007078">NM_007078</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001368063">NM_001368063</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001368064">NM_001368064</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001368065">NM_001368065</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001368066">NM_001368066</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001368067">NM_001368067</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001368068">NM_001368068</a></span></p></td></tr></tbody></table></td><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001039071">NM_001039071</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001039072">NM_001039072</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001039073">NM_001039073</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001039074">NM_001039074</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001039075">NM_001039075</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001039076">NM_001039076</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_011918">NM_011918</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (protein)</th><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001073583">NP_001073583</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001073584">NP_001073584</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001073585">NP_001073585</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001165081">NP_001165081</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001165082">NP_001165082</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_009009">NP_009009</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001354992">NP_001354992</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001354993">NP_001354993</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001354994">NP_001354994</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001354995">NP_001354995</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001354996">NP_001354996</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001354997">NP_001354997</a></span></p></td></tr></tbody></table></td><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034160">NP_001034160</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034161">NP_001034161</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034162">NP_001034162</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034163">NP_001034163</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034164">NP_001034164</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034165">NP_001034165</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_036048">NP_036048</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr10:86666785-86736072">Chr 10: 86.67 – 86.74 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr14:34248560-34310639">Chr 14: 34.25 – 34.31 Mb</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18036165" class="extiw" title="d:Q18036165">View/Edit Human</a></td><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18255696" class="extiw" title="d:Q18255696">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>LIM domain binding 3</b> (<b>LDB3</b>), also known as <b>Z-band alternatively spliced PDZ-motif</b> (<b>ZASP</b>), is a <a href="/wiki/Protein" title="Protein">protein</a> which in humans is encoded by the <i>LDB3</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-entrez_5-0" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10427098_6-0" class="reference"><a href="#cite_note-pmid10427098-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> ZASP belongs to the Enigma subfamily of proteins and stabilizes the <a href="/wiki/Sarcomere" title="Sarcomere">sarcomere</a> (the basic units of muscles) during contraction, through interactions with <a href="/wiki/Actinin,_alpha_2" class="mw-redirect" title="Actinin, alpha 2">actin</a> in <a href="/wiki/Cardiac_muscle" title="Cardiac muscle">cardiac</a> and <a href="/wiki/Skeletal_muscle" title="Skeletal muscle">skeletal muscles</a>. Mutations in the ZASP gene has been associated with several <a href="/wiki/Myopathy" title="Myopathy">muscular diseases</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Structure">Structure</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=1" title="Edit section: Structure"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ZASP is a <a href="/wiki/PDZ_domain" title="PDZ domain">PDZ domain</a>-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in <a href="/wiki/Cytoskeleton" title="Cytoskeleton">cytoskeletal</a> assembly or with other proteins involved in targeting and clustering of membrane proteins. ZASP interacts with alpha-<a href="/wiki/Actinin" title="Actinin">actinin</a>-2 through its <a href="/wiki/N-terminus" title="N-terminus">N-terminal</a> PDZ domain and with <a href="/wiki/Protein_kinase_C" title="Protein kinase C">protein kinase C</a> via its <a href="/wiki/C-terminus" title="C-terminus">C-terminal</a> <a href="/wiki/LIM_domain" title="LIM domain">LIM domains</a>. The LIM domain is a <a href="/wiki/Cysteine" title="Cysteine">cysteine</a>-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the <a href="/wiki/MYOZ1" title="MYOZ1">myozenin</a> family.<sup id="cite_ref-entrez_5-1" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Human ZASP can exist in cardiac and skeletal cells as six distinct isoforms, based on alternative splicing of 16 exons.<sup id="cite_ref-Sheikh_F_2007_7-0" class="reference"><a href="#cite_note-Sheikh_F_2007-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> There are 2 ZASP short forms (Uniprot ID: O75112-6, 31.0 kDa, 283 amino acids;<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> and Uniprot ID: O75112-5, 35.6 kDa, 330 amino acids);<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> and 4 ZASP long forms (Uniprot ID: O75112-4, 42.8 kDa, 398 amino acids;<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Uniprot ID: O75112-3, 50.6 kDa, 470 amino acids;<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Uniprot ID: O75112-2, 66.6 kDa, 617 amino acids;<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> and Uniprot ID: O75112, 77.1 kDa, 727 amino acids).<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> All ZASP isoforms have an N-terminal <a href="/wiki/PDZ_domain" title="PDZ domain">PDZ domain</a>; internal, conserved sequences known as ZASP-like motifs (ZMs); and the four long isoforms have three <a href="/wiki/C-terminus" title="C-terminus">C-terminal</a> <a href="/wiki/LIM_domain" title="LIM domain">LIM domains</a>.<sup id="cite_ref-Sheikh_F_2007_7-1" class="reference"><a href="#cite_note-Sheikh_F_2007-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Function">Function</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=2" title="Edit section: Function"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ZASP functions to maintain structural integrity of sarcomeres during contraction, and has been shown to be involved in <a href="/wiki/Protein_kinase_A" title="Protein kinase A">protein kinase A</a> signaling.<sup id="cite_ref-ReferenceB_15-0" class="reference"><a href="#cite_note-ReferenceB-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> ZASP has also been shown to co-activate α5β1 integrins along with the protein <a href="/wiki/Talin_protein" class="mw-redirect" title="Talin protein">TLN1</a>.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Clinical_significance">Clinical significance</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=3" title="Edit section: Clinical significance"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mutations in ZASP have been associated with <a href="/wiki/Myofibril" title="Myofibril">myofibrillar</a> <a href="/wiki/Myopathy" title="Myopathy">myopathy</a>,<sup id="cite_ref-pmid15668942_17-0" class="reference"><a href="#cite_note-pmid15668942-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Dilated_cardiomyopathy" title="Dilated cardiomyopathy">dilated cardiomyopathy</a>,<sup id="cite_ref-pmid14662268_18-0" class="reference"><a href="#cite_note-pmid14662268-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid14660611_19-0" class="reference"><a href="#cite_note-pmid14660611-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Arrhythmogenic_right_ventricular_cardiomyopathy" class="mw-redirect" title="Arrhythmogenic right ventricular cardiomyopathy">arrhythmogenic right ventricular cardiomyopathy</a>,<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Noncompaction_cardiomyopathy" title="Noncompaction cardiomyopathy">noncompaction cardiomyopathy</a>,<sup id="cite_ref-pmid14662268_18-1" class="reference"><a href="#cite_note-pmid14662268-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> and <a href="/wiki/Muscular_dystrophy" title="Muscular dystrophy">muscular dystrophy</a>.<sup id="cite_ref-pmid15668942_17-1" class="reference"><a href="#cite_note-pmid15668942-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Interactions">Interactions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=4" title="Edit section: Interactions"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The <a href="/wiki/PDZ_domain" title="PDZ domain">PDZ domain</a> of ZASP binds the <a href="/wiki/C-terminus" title="C-terminus">C-terminus</a> of <a href="/wiki/Actinin,_alpha_2" class="mw-redirect" title="Actinin, alpha 2">alpha actinin-2</a><sup id="cite_ref-pmid10427098_6-1" class="reference"><a href="#cite_note-pmid10427098-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-ReferenceC_22-0" class="reference"><a href="#cite_note-ReferenceC-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> and ZMs bind the rod domain of <a href="/wiki/Actinin,_alpha_2" class="mw-redirect" title="Actinin, alpha 2">alpha actinin-2</a>.<sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/LIM_domain" title="LIM domain">LIM domains</a> have been shown to interact with <a href="/wiki/Protein_kinase_C" title="Protein kinase C">protein kinase C</a>.<sup id="cite_ref-ReferenceC_22-1" class="reference"><a href="#cite_note-ReferenceC-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> The cardiac-specific region of ZASP encoded by exon 4 includes a ZP motif and binds a regulatory subunit of <a href="/wiki/Protein_kinase_A" title="Protein kinase A">protein kinase A</a>.<sup id="cite_ref-ReferenceB_15-1" class="reference"><a href="#cite_note-ReferenceB-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=5" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Dilated_cardiomyopathy" title="Dilated cardiomyopathy">Dilated cardiomyopathy</a></li> <li><a href="/wiki/Noncompaction_cardiomyopathy" title="Noncompaction cardiomyopathy">Noncompaction cardiomyopathy</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=6" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width" style="column-width: 33em;"> <ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000122367">GRCh38: Ensembl release 89: ENSG00000122367</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000021798">GRCm38: Ensembl release 89: ENSMUSG00000021798</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=11155">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D11155&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=24131">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D24131&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-entrez-5"><span class="mw-cite-backlink">^ <a href="#cite_ref-entrez_5-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-entrez_5-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11155">"Entrez Gene: LDB3 LIM domain binding 3"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+LDB3+LIM+domain+binding+3&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D11155&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-pmid10427098-6"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid10427098_6-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid10427098_6-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFaulknerPallaviciniFormentinComelli1999" class="citation journal cs1">Faulkner G, Pallavicini A, Formentin E, Comelli A, Ievolella C, Trevisan S, et al. (July 1999). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206570">"ZASP: a new Z-band alternatively spliced PDZ-motif protein"</a>. <i>J Cell Biol</i>. <b>146</b> (2): 465–75. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1083%2Fjcb.146.2.465">10.1083/jcb.146.2.465</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206570">3206570</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10427098">10427098</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J+Cell+Biol&rft.atitle=ZASP%3A+a+new+Z-band+alternatively+spliced+PDZ-motif+protein&rft.volume=146&rft.issue=2&rft.pages=465-75&rft.date=1999-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3206570%23id-name%3DPMC&rft_id=info%3Apmid%2F10427098&rft_id=info%3Adoi%2F10.1083%2Fjcb.146.2.465&rft.aulast=Faulkner&rft.aufirst=G&rft.au=Pallavicini%2C+A&rft.au=Formentin%2C+E&rft.au=Comelli%2C+A&rft.au=Ievolella%2C+C&rft.au=Trevisan%2C+S&rft.au=Bortoletto%2C+G&rft.au=Scannapieco%2C+P&rft.au=Salamon%2C+M&rft.au=Mouly%2C+V&rft.au=Valle%2C+G&rft.au=Lanfranchi%2C+G&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3206570&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-Sheikh_F_2007-7"><span class="mw-cite-backlink">^ <a href="#cite_ref-Sheikh_F_2007_7-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Sheikh_F_2007_7-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSheikhBangLangeChen2007" class="citation journal cs1">Sheikh F, Bang ML, Lange S, Chen J (Nov 2007). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134983">"<span class="cs1-kern-left"></span>"Z"eroing in on the role of Cypher in striated muscle function, signaling, and human disease"</a>. <i>Trends in Cardiovascular Medicine</i>. <b>17</b> (8): 258–62. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.tcm.2007.09.002">10.1016/j.tcm.2007.09.002</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134983">2134983</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18021935">18021935</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Trends+in+Cardiovascular+Medicine&rft.atitle=%22Z%22eroing+in+on+the+role+of+Cypher+in+striated+muscle+function%2C+signaling%2C+and+human+disease&rft.volume=17&rft.issue=8&rft.pages=258-62&rft.date=2007-11&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2134983%23id-name%3DPMC&rft_id=info%3Apmid%2F18021935&rft_id=info%3Adoi%2F10.1016%2Fj.tcm.2007.09.002&rft.aulast=Sheikh&rft.aufirst=F&rft.au=Bang%2C+ML&rft.au=Lange%2C+S&rft.au=Chen%2C+J&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2134983&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150613073747/http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-6">"O75112-6"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-6">the original</a> on 2015-06-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2015-06-11</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=O75112-6&rft_id=http%3A%2F%2Fwww.heartproteome.org%2Fcopa%2FProteinInfo.aspx%3FQType%3DProtein%2520ID%26QValue%3DO75112-6&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150613120022/http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-5">"O75112-5"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-5">the original</a> on 2015-06-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2015-06-11</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=O75112-5&rft_id=http%3A%2F%2Fwww.heartproteome.org%2Fcopa%2FProteinInfo.aspx%3FQType%3DProtein%2520ID%26QValue%3DO75112-5&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150613070404/http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-4">"O75112-4"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-4">the original</a> on 2015-06-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2015-06-11</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=O75112-4&rft_id=http%3A%2F%2Fwww.heartproteome.org%2Fcopa%2FProteinInfo.aspx%3FQType%3DProtein%2520ID%26QValue%3DO75112-4&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-11">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150613073153/http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-3">"O75112-3"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-3">the original</a> on 2015-06-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2015-06-11</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=O75112-3&rft_id=http%3A%2F%2Fwww.heartproteome.org%2Fcopa%2FProteinInfo.aspx%3FQType%3DProtein%2520ID%26QValue%3DO75112-3&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150613103726/http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-2">"O75112-2"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112-2">the original</a> on 2015-06-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2015-06-11</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=O75112-2&rft_id=http%3A%2F%2Fwww.heartproteome.org%2Fcopa%2FProteinInfo.aspx%3FQType%3DProtein%2520ID%26QValue%3DO75112-2&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-13">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20150613071704/http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112">"O75112"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.heartproteome.org/copa/ProteinInfo.aspx?QType=Protein%20ID&QValue=O75112">the original</a> on 2015-06-13<span class="reference-accessdate">. Retrieved <span class="nowrap">2015-06-11</span></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=O75112&rft_id=http%3A%2F%2Fwww.heartproteome.org%2Fcopa%2FProteinInfo.aspx%3FQType%3DProtein%2520ID%26QValue%3DO75112&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-14">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZongLiLiLam2013" class="citation journal cs1">Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, et al. (Oct 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076475">"Integration of cardiac proteome biology and medicine by a specialized knowledgebase"</a>. <i>Circulation Research</i>. <b>113</b> (9): 1043–53. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1161%2FCIRCRESAHA.113.301151">10.1161/CIRCRESAHA.113.301151</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076475">4076475</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23965338">23965338</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Circulation+Research&rft.atitle=Integration+of+cardiac+proteome+biology+and+medicine+by+a+specialized+knowledgebase&rft.volume=113&rft.issue=9&rft.pages=1043-53&rft.date=2013-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4076475%23id-name%3DPMC&rft_id=info%3Apmid%2F23965338&rft_id=info%3Adoi%2F10.1161%2FCIRCRESAHA.113.301151&rft.aulast=Zong&rft.aufirst=NC&rft.au=Li%2C+H&rft.au=Li%2C+H&rft.au=Lam%2C+MP&rft.au=Jimenez%2C+RC&rft.au=Kim%2C+CS&rft.au=Deng%2C+N&rft.au=Kim%2C+AK&rft.au=Choi%2C+JH&rft.au=Zelaya%2C+I&rft.au=Liem%2C+D&rft.au=Meyer%2C+D&rft.au=Odeberg%2C+J&rft.au=Fang%2C+C&rft.au=Lu%2C+HJ&rft.au=Xu%2C+T&rft.au=Weiss%2C+J&rft.au=Duan%2C+H&rft.au=Uhlen%2C+M&rft.au=Yates%2C+JR&rft.au=Apweiler%2C+R&rft.au=Ge%2C+J&rft.au=Hermjakob%2C+H&rft.au=Ping%2C+P&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4076475&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-ReferenceB-15"><span class="mw-cite-backlink">^ <a href="#cite_ref-ReferenceB_15-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-ReferenceB_15-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLinGuoLangeLiu2013" class="citation journal cs1">Lin C, Guo X, Lange S, Liu J, Ouyang K, Yin X, et al. (Oct 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795241">"Cypher/ZASP is a novel A-kinase anchoring protein"</a>. <i>The Journal of Biological Chemistry</i>. <b>288</b> (41): 29403–13. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M113.470708">10.1074/jbc.M113.470708</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795241">3795241</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23996002">23996002</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Cypher%2FZASP+is+a+novel+A-kinase+anchoring+protein&rft.volume=288&rft.issue=41&rft.pages=29403-13&rft.date=2013-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3795241%23id-name%3DPMC&rft_id=info%3Apmid%2F23996002&rft_id=info%3Adoi%2F10.1074%2Fjbc.M113.470708&rft.aulast=Lin&rft.aufirst=C&rft.au=Guo%2C+X&rft.au=Lange%2C+S&rft.au=Liu%2C+J&rft.au=Ouyang%2C+K&rft.au=Yin%2C+X&rft.au=Jiang%2C+L&rft.au=Cai%2C+Y&rft.au=Mu%2C+Y&rft.au=Sheikh%2C+F&rft.au=Ye%2C+S&rft.au=Chen%2C+J&rft.au=Ke%2C+Y&rft.au=Cheng%2C+H&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3795241&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBouaouinaJaniLongCzerniecki2012" class="citation journal cs1">Bouaouina M, Jani K, Long JY, Czerniecki S, Morse EM, Ellis SJ, et al. (Dec 2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575701">"Zasp regulates integrin activation"</a>. <i>Journal of Cell Science</i>. <b>125</b> (Pt 23): 5647–57. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1242%2Fjcs.103291">10.1242/jcs.103291</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575701">3575701</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22992465">22992465</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Cell+Science&rft.atitle=Zasp+regulates+integrin+activation&rft.volume=125&rft.issue=Pt+23&rft.pages=5647-57&rft.date=2012-12&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3575701%23id-name%3DPMC&rft_id=info%3Apmid%2F22992465&rft_id=info%3Adoi%2F10.1242%2Fjcs.103291&rft.aulast=Bouaouina&rft.aufirst=M&rft.au=Jani%2C+K&rft.au=Long%2C+JY&rft.au=Czerniecki%2C+S&rft.au=Morse%2C+EM&rft.au=Ellis%2C+SJ&rft.au=Tanentzapf%2C+G&rft.au=Sch%C3%B6ck%2C+F&rft.au=Calderwood%2C+DA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3575701&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-pmid15668942-17"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid15668942_17-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid15668942_17-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSelcenEngel2005" class="citation journal cs1">Selcen D, Engel AG (Feb 2005). "Mutations in ZASP define a novel form of muscular dystrophy in humans". <i>Annals of Neurology</i>. <b>57</b> (2): 269–76. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fana.20376">10.1002/ana.20376</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15668942">15668942</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:25733755">25733755</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Annals+of+Neurology&rft.atitle=Mutations+in+ZASP+define+a+novel+form+of+muscular+dystrophy+in+humans&rft.volume=57&rft.issue=2&rft.pages=269-76&rft.date=2005-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A25733755%23id-name%3DS2CID&rft_id=info%3Apmid%2F15668942&rft_id=info%3Adoi%2F10.1002%2Fana.20376&rft.aulast=Selcen&rft.aufirst=D&rft.au=Engel%2C+AG&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-pmid14662268-18"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid14662268_18-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid14662268_18-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVattaMohapatraJimenezSanchez2003" class="citation journal cs1">Vatta M, Mohapatra B, Jimenez S, Sanchez X, Faulkner G, Perles Z, et al. (Dec 2003). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.jacc.2003.10.021">"Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction"</a>. <i>Journal of the American College of Cardiology</i>. <b>42</b> (11): 2014–27. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.jacc.2003.10.021">10.1016/j.jacc.2003.10.021</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/14662268">14662268</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+the+American+College+of+Cardiology&rft.atitle=Mutations+in+Cypher%2FZASP+in+patients+with+dilated+cardiomyopathy+and+left+ventricular+non-compaction&rft.volume=42&rft.issue=11&rft.pages=2014-27&rft.date=2003-12&rft_id=info%3Adoi%2F10.1016%2Fj.jacc.2003.10.021&rft_id=info%3Apmid%2F14662268&rft.aulast=Vatta&rft.aufirst=M&rft.au=Mohapatra%2C+B&rft.au=Jimenez%2C+S&rft.au=Sanchez%2C+X&rft.au=Faulkner%2C+G&rft.au=Perles%2C+Z&rft.au=Sinagra%2C+G&rft.au=Lin%2C+JH&rft.au=Vu%2C+TM&rft.au=Zhou%2C+Q&rft.au=Bowles%2C+KR&rft.au=Di+Lenarda%2C+A&rft.au=Schimmenti%2C+L&rft.au=Fox%2C+M&rft.au=Chrisco%2C+MA&rft.au=Murphy%2C+RT&rft.au=McKenna%2C+W&rft.au=Elliott%2C+P&rft.au=Bowles%2C+NE&rft.au=Chen%2C+J&rft.au=Valle%2C+G&rft.au=Towbin%2C+JA&rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252Fj.jacc.2003.10.021&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-pmid14660611-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid14660611_19-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFArimuraHayashiTeradaLee2004" class="citation journal cs1">Arimura T, Hayashi T, Terada H, Lee SY, Zhou Q, Takahashi M, Ueda K, Nouchi T, Hohda S, Shibutani M, Hirose M, Chen J, Park JE, Yasunami M, Hayashi H, Kimura A (Feb 2004). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M311849200">"A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C"</a>. <i>The Journal of Biological Chemistry</i>. <b>279</b> (8): 6746–52. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M311849200">10.1074/jbc.M311849200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/14660611">14660611</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=A+Cypher%2FZASP+mutation+associated+with+dilated+cardiomyopathy+alters+the+binding+affinity+to+protein+kinase+C&rft.volume=279&rft.issue=8&rft.pages=6746-52&rft.date=2004-02&rft_id=info%3Adoi%2F10.1074%2Fjbc.M311849200&rft_id=info%3Apmid%2F14660611&rft.aulast=Arimura&rft.aufirst=T&rft.au=Hayashi%2C+T&rft.au=Terada%2C+H&rft.au=Lee%2C+SY&rft.au=Zhou%2C+Q&rft.au=Takahashi%2C+M&rft.au=Ueda%2C+K&rft.au=Nouchi%2C+T&rft.au=Hohda%2C+S&rft.au=Shibutani%2C+M&rft.au=Hirose%2C+M&rft.au=Chen%2C+J&rft.au=Park%2C+JE&rft.au=Yasunami%2C+M&rft.au=Hayashi%2C+H&rft.au=Kimura%2C+A&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M311849200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-20">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLopez-AyalaOrtiz-GengaGomez-MilanesLopez-Cuenca2014" class="citation journal cs1">Lopez-Ayala JM, Ortiz-Genga M, Gomez-Milanes I, Lopez-Cuenca D, Ruiz-Espejo F, Sanchez-Munoz JJ, et al. (Jul 2014). "A mutation in the Z-line Cypher/ZASP protein is associated with arrhythmogenic right ventricular cardiomyopathy". <i>Clinical Genetics</i>. <b>88</b> (2): 172–6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fcge.12458">10.1111/cge.12458</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25041374">25041374</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21822009">21822009</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clinical+Genetics&rft.atitle=A+mutation+in+the+Z-line+Cypher%2FZASP+protein+is+associated+with+arrhythmogenic+right+ventricular+cardiomyopathy&rft.volume=88&rft.issue=2&rft.pages=172-6&rft.date=2014-07&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21822009%23id-name%3DS2CID&rft_id=info%3Apmid%2F25041374&rft_id=info%3Adoi%2F10.1111%2Fcge.12458&rft.aulast=Lopez-Ayala&rft.aufirst=JM&rft.au=Ortiz-Genga%2C+M&rft.au=Gomez-Milanes%2C+I&rft.au=Lopez-Cuenca%2C+D&rft.au=Ruiz-Espejo%2C+F&rft.au=Sanchez-Munoz%2C+JJ&rft.au=Oliva-Sandoval%2C+MJ&rft.au=Monserrat%2C+L&rft.au=Gimeno%2C+JR&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-21">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFXiAiDe_LangeLi2012" class="citation journal cs1">Xi Y, Ai T, De Lange E, Li Z, Wu G, Brunelli L, et al. (Oct 2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331025">"Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompaction"</a>. <i>Circulation: Arrhythmia and Electrophysiology</i>. <b>5</b> (5): 1017–26. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1161%2FCIRCEP.111.969220">10.1161/CIRCEP.111.969220</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331025">4331025</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22929165">22929165</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Circulation%3A+Arrhythmia+and+Electrophysiology&rft.atitle=Loss+of+function+of+hNav1.5+by+a+ZASP1+mutation+associated+with+intraventricular+conduction+disturbances+in+left+ventricular+noncompaction&rft.volume=5&rft.issue=5&rft.pages=1017-26&rft.date=2012-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4331025%23id-name%3DPMC&rft_id=info%3Apmid%2F22929165&rft_id=info%3Adoi%2F10.1161%2FCIRCEP.111.969220&rft.aulast=Xi&rft.aufirst=Y&rft.au=Ai%2C+T&rft.au=De+Lange%2C+E&rft.au=Li%2C+Z&rft.au=Wu%2C+G&rft.au=Brunelli%2C+L&rft.au=Kyle%2C+WB&rft.au=Turker%2C+I&rft.au=Cheng%2C+J&rft.au=Ackerman%2C+MJ&rft.au=Kimura%2C+A&rft.au=Weiss%2C+JN&rft.au=Qu%2C+Z&rft.au=Kim%2C+JJ&rft.au=Faulkner%2C+G&rft.au=Vatta%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4331025&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-ReferenceC-22"><span class="mw-cite-backlink">^ <a href="#cite_ref-ReferenceC_22-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-ReferenceC_22-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZhouRuiz-LozanoMartoneChen1999" class="citation journal cs1">Zhou Q, Ruiz-Lozano P, Martone ME, Chen J (Jul 1999). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.274.28.19807">"Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C"</a>. <i>The Journal of Biological Chemistry</i>. <b>274</b> (28): 19807–13. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.274.28.19807">10.1074/jbc.274.28.19807</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10391924">10391924</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Cypher%2C+a+striated+muscle-restricted+PDZ+and+LIM+domain-containing+protein%2C+binds+to+alpha-actinin-2+and+protein+kinase+C&rft.volume=274&rft.issue=28&rft.pages=19807-13&rft.date=1999-07&rft_id=info%3Adoi%2F10.1074%2Fjbc.274.28.19807&rft_id=info%3Apmid%2F10391924&rft.aulast=Zhou&rft.aufirst=Q&rft.au=Ruiz-Lozano%2C+P&rft.au=Martone%2C+ME&rft.au=Chen%2C+J&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.274.28.19807&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-23"><span class="mw-cite-backlink"><b><a href="#cite_ref-23">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKlaavuniemiYlänne2006" class="citation journal cs1">Klaavuniemi T, Ylänne J (May 2006). "Zasp/Cypher internal ZM-motif containing fragments are sufficient to co-localize with alpha-actinin--analysis of patient mutations". <i>Experimental Cell Research</i>. <b>312</b> (8): 1299–311. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.yexcr.2005.12.036">10.1016/j.yexcr.2005.12.036</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16476425">16476425</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Experimental+Cell+Research&rft.atitle=Zasp%2FCypher+internal+ZM-motif+containing+fragments+are+sufficient+to+co-localize+with+alpha-actinin--analysis+of+patient+mutations&rft.volume=312&rft.issue=8&rft.pages=1299-311&rft.date=2006-05&rft_id=info%3Adoi%2F10.1016%2Fj.yexcr.2005.12.036&rft_id=info%3Apmid%2F16476425&rft.aulast=Klaavuniemi&rft.aufirst=T&rft.au=Yl%C3%A4nne%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> <li id="cite_note-24"><span class="mw-cite-backlink"><b><a href="#cite_ref-24">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKurodaTokunagaKiyoharaHiguchi1996" class="citation journal cs1">Kuroda S, Tokunaga C, Kiyohara Y, Higuchi O, Konishi H, Mizuno K, et al. (Dec 1996). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.271.49.31029">"Protein-protein interaction of zinc finger LIM domains with protein kinase C"</a>. <i>The Journal of Biological Chemistry</i>. <b>271</b> (49): 31029–32. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.271.49.31029">10.1074/jbc.271.49.31029</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8940095">8940095</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Protein-protein+interaction+of+zinc+finger+LIM+domains+with+protein+kinase+C&rft.volume=271&rft.issue=49&rft.pages=31029-32&rft.date=1996-12&rft_id=info%3Adoi%2F10.1074%2Fjbc.271.49.31029&rft_id=info%3Apmid%2F8940095&rft.aulast=Kuroda&rft.aufirst=S&rft.au=Tokunaga%2C+C&rft.au=Kiyohara%2C+Y&rft.au=Higuchi%2C+O&rft.au=Konishi%2C+H&rft.au=Mizuno%2C+K&rft.au=Gill%2C+GN&rft.au=Kikkawa%2C+U&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.271.49.31029&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=7" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 33em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarzilianoMannarinoNespoliDiegoli2007" class="citation journal cs1">Marziliano N, Mannarino S, Nespoli L, Diegoli M, Pasotti M, Malattia C, et al. (May 2007). "Barth syndrome associated with compound hemizygosity and heterozygosity of the TAZ and LDB3 genes". <i>American Journal of Medical Genetics Part A</i>. <b>143A</b> (9): 907–15. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fajmg.a.31653">10.1002/ajmg.a.31653</a>. <a href="/wiki/Hdl_(identifier)" class="mw-redirect" title="Hdl (identifier)">hdl</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://hdl.handle.net/2434%2F45968">2434/45968</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17394203">17394203</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:20328643">20328643</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Medical+Genetics+Part+A&rft.atitle=Barth+syndrome+associated+with+compound+hemizygosity+and+heterozygosity+of+the+TAZ+and+LDB3+genes&rft.volume=143A&rft.issue=9&rft.pages=907-15&rft.date=2007-05&rft_id=info%3Ahdl%2F2434%2F45968&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A20328643%23id-name%3DS2CID&rft_id=info%3Apmid%2F17394203&rft_id=info%3Adoi%2F10.1002%2Fajmg.a.31653&rft.aulast=Marziliano&rft.aufirst=N&rft.au=Mannarino%2C+S&rft.au=Nespoli%2C+L&rft.au=Diegoli%2C+M&rft.au=Pasotti%2C+M&rft.au=Malattia%2C+C&rft.au=Grasso%2C+M&rft.au=Pilotto%2C+A&rft.au=Porcu%2C+E&rft.au=Raisaro%2C+A&rft.au=Raineri%2C+C&rft.au=Dore%2C+R&rft.au=Maggio%2C+PP&rft.au=Brega%2C+A&rft.au=Arbustini%2C+E&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKlaavuniemiYlänne2006" class="citation journal cs1">Klaavuniemi T, Ylänne J (May 2006). "Zasp/Cypher internal ZM-motif containing fragments are sufficient to co-localize with alpha-actinin--analysis of patient mutations". <i>Experimental Cell Research</i>. <b>312</b> (8): 1299–311. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.yexcr.2005.12.036">10.1016/j.yexcr.2005.12.036</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16476425">16476425</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Experimental+Cell+Research&rft.atitle=Zasp%2FCypher+internal+ZM-motif+containing+fragments+are+sufficient+to+co-localize+with+alpha-actinin--analysis+of+patient+mutations&rft.volume=312&rft.issue=8&rft.pages=1299-311&rft.date=2006-05&rft_id=info%3Adoi%2F10.1016%2Fj.yexcr.2005.12.036&rft_id=info%3Apmid%2F16476425&rft.aulast=Klaavuniemi&rft.aufirst=T&rft.au=Yl%C3%A4nne%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKimuraWakamatsuSuzukiOta2006" class="citation journal cs1">Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, et al. (Jan 2006). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129">"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"</a>. <i>Genome Research</i>. <b>16</b> (1): 55–65. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1101%2Fgr.4039406">10.1101/gr.4039406</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129">1356129</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16344560">16344560</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genome+Research&rft.atitle=Diversification+of+transcriptional+modulation%3A+large-scale+identification+and+characterization+of+putative+alternative+promoters+of+human+genes&rft.volume=16&rft.issue=1&rft.pages=55-65&rft.date=2006-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1356129%23id-name%3DPMC&rft_id=info%3Apmid%2F16344560&rft_id=info%3Adoi%2F10.1101%2Fgr.4039406&rft.aulast=Kimura&rft.aufirst=K&rft.au=Wakamatsu%2C+A&rft.au=Suzuki%2C+Y&rft.au=Ota%2C+T&rft.au=Nishikawa%2C+T&rft.au=Yamashita%2C+R&rft.au=Yamamoto%2C+J&rft.au=Sekine%2C+M&rft.au=Tsuritani%2C+K&rft.au=Wakaguri%2C+H&rft.au=Ishii%2C+S&rft.au=Sugiyama%2C+T&rft.au=Saito%2C+K&rft.au=Isono%2C+Y&rft.au=Irie%2C+R&rft.au=Kushida%2C+N&rft.au=Yoneyama%2C+T&rft.au=Otsuka%2C+R&rft.au=Kanda%2C+K&rft.au=Yokoi%2C+T&rft.au=Kondo%2C+H&rft.au=Wagatsuma%2C+M&rft.au=Murakawa%2C+K&rft.au=Ishida%2C+S&rft.au=Ishibashi%2C+T&rft.au=Takahashi-Fujii%2C+A&rft.au=Tanase%2C+T&rft.au=Nagai%2C+K&rft.au=Kikuchi%2C+H&rft.au=Nakai%2C+K&rft.au=Isogai%2C+T&rft.au=Sugano%2C+S&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1356129&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFreyOlson2002" class="citation journal cs1">Frey N, Olson EN (Apr 2002). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M200712200">"Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins"</a>. <i>The Journal of Biological Chemistry</i>. <b>277</b> (16): 13998–4004. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M200712200">10.1074/jbc.M200712200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11842093">11842093</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Calsarcin-3%2C+a+novel+skeletal+muscle-specific+member+of+the+calsarcin+family%2C+interacts+with+multiple+Z-disc+proteins&rft.volume=277&rft.issue=16&rft.pages=13998-4004&rft.date=2002-04&rft_id=info%3Adoi%2F10.1074%2Fjbc.M200712200&rft_id=info%3Apmid%2F11842093&rft.aulast=Frey&rft.aufirst=N&rft.au=Olson%2C+EN&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.M200712200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHartleyTempleBrasch2000" class="citation journal cs1">Hartley JL, Temple GF, Brasch MA (Nov 2000). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310948">"DNA cloning using in vitro site-specific recombination"</a>. <i>Genome Research</i>. <b>10</b> (11): 1788–95. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1101%2Fgr.143000">10.1101/gr.143000</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310948">310948</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11076863">11076863</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genome+Research&rft.atitle=DNA+cloning+using+in+vitro+site-specific+recombination&rft.volume=10&rft.issue=11&rft.pages=1788-95&rft.date=2000-11&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC310948%23id-name%3DPMC&rft_id=info%3Apmid%2F11076863&rft_id=info%3Adoi%2F10.1101%2Fgr.143000&rft.aulast=Hartley&rft.aufirst=JL&rft.au=Temple%2C+GF&rft.au=Brasch%2C+MA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC310948&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPassierRichardsonOlson2000" class="citation journal cs1">Passier R, Richardson JA, Olson EN (Apr 2000). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0925-4773%2899%2900330-5">"Oracle, a novel PDZ-LIM domain protein expressed in heart and skeletal muscle"</a>. <i>Mechanisms of Development</i>. <b>92</b> (2): 277–84. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0925-4773%2899%2900330-5">10.1016/S0925-4773(99)00330-5</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10727866">10727866</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:18254892">18254892</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mechanisms+of+Development&rft.atitle=Oracle%2C+a+novel+PDZ-LIM+domain+protein+expressed+in+heart+and+skeletal+muscle&rft.volume=92&rft.issue=2&rft.pages=277-84&rft.date=2000-04&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A18254892%23id-name%3DS2CID&rft_id=info%3Apmid%2F10727866&rft_id=info%3Adoi%2F10.1016%2FS0925-4773%2899%2900330-5&rft.aulast=Passier&rft.aufirst=R&rft.au=Richardson%2C+JA&rft.au=Olson%2C+EN&rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252FS0925-4773%252899%252900330-5&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFIshikawaNagaseSuyamaMiyajima1998" class="citation journal cs1">Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jun 1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fdnares%2F5.3.169">"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro"</a>. <i>DNA Research</i>. <b>5</b> (3): 169–76. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fdnares%2F5.3.169">10.1093/dnares/5.3.169</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9734811">9734811</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=DNA+Research&rft.atitle=Prediction+of+the+coding+sequences+of+unidentified+human+genes.+X.+The+complete+sequences+of+100+new+cDNA+clones+from+brain+which+can+code+for+large+proteins+in+vitro&rft.volume=5&rft.issue=3&rft.pages=169-76&rft.date=1998-06&rft_id=info%3Adoi%2F10.1093%2Fdnares%2F5.3.169&rft_id=info%3Apmid%2F9734811&rft.aulast=Ishikawa&rft.aufirst=K&rft.au=Nagase%2C+T&rft.au=Suyama%2C+M&rft.au=Miyajima%2C+N&rft.au=Tanaka%2C+A&rft.au=Kotani%2C+H&rft.au=Nomura%2C+N&rft.au=Ohara%2C+O&rft_id=https%3A%2F%2Fdoi.org%2F10.1093%252Fdnares%252F5.3.169&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLanfranchiMuraroCaldaraPacchioni1996" class="citation journal cs1">Lanfranchi G, Muraro T, Caldara F, Pacchioni B, Pallavicini A, Pandolfo D, et al. (Jan 1996). <a rel="nofollow" class="external text" href="https://doi.org/10.1101%2Fgr.6.1.35">"Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization"</a>. <i>Genome Research</i>. <b>6</b> (1): 35–42. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1101%2Fgr.6.1.35">10.1101/gr.6.1.35</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8681137">8681137</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genome+Research&rft.atitle=Identification+of+4370+expressed+sequence+tags+from+a+3%27-end-specific+cDNA+library+of+human+skeletal+muscle+by+DNA+sequencing+and+filter+hybridization&rft.volume=6&rft.issue=1&rft.pages=35-42&rft.date=1996-01&rft_id=info%3Adoi%2F10.1101%2Fgr.6.1.35&rft_id=info%3Apmid%2F8681137&rft.aulast=Lanfranchi&rft.aufirst=G&rft.au=Muraro%2C+T&rft.au=Caldara%2C+F&rft.au=Pacchioni%2C+B&rft.au=Pallavicini%2C+A&rft.au=Pandolfo%2C+D&rft.au=Toppo%2C+S&rft.au=Trevisan%2C+S&rft.au=Scarso%2C+S&rft.au=Valle%2C+G&rft_id=https%3A%2F%2Fdoi.org%2F10.1101%252Fgr.6.1.35&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALDB3" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=LDB3&action=edit&section=8" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=mfm">GeneReviews/NIH/NCBI/UW entry on Myofibrillar Myopathy</a></li> <li>Overview of all the structural information available in the <a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a> for <a href="/wiki/UniProt" title="UniProt">UniProt</a>: <i><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/O75112">O75112</a></i> (Human LIM domain-binding protein 3) at the <a href="/wiki/PDBe-KB" title="PDBe-KB">PDBe-KB</a>.</li> <li>Overview of all the structural information available in the <a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a> for <a href="/wiki/UniProt" title="UniProt">UniProt</a>: <i><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/Q9JKS4">Q9JKS4</a></i> (Mouse LIM domain-binding protein 3) at the <a href="/wiki/PDBe-KB" title="PDBe-KB">PDBe-KB</a>.</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist 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template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Signal_transducing_adaptor_proteins" title="Special:EditPage/Template:Signal transducing adaptor proteins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Cell_signaling:_carrier_proteins:_signal_transducing_adaptor_proteins" style="font-size:114%;margin:0 4em"><a href="/wiki/Cell_signaling" title="Cell signaling">Cell signaling</a>: <a href="/wiki/Carrier_protein" class="mw-redirect" title="Carrier protein">carrier proteins</a>: <a href="/wiki/Signal_transducing_adaptor_protein" title="Signal transducing adaptor protein">signal transducing adaptor proteins</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/JAK-STAT_signaling_pathway" title="JAK-STAT signaling pathway">JAK-STAT</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>see</i> <a href="/wiki/Template:JAK-STAT_signaling_pathway" title="Template:JAK-STAT signaling pathway">JAK-STAT signaling pathway</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Growth_factor" title="Growth factor">Growth factor</a> receptor-bound protein</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/GRB2" title="GRB2">GRB2</a></li> <li><a href="/wiki/GRB7" title="GRB7">GRB7</a></li> <li><a href="/wiki/GRB10" title="GRB10">GRB10</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/14-3-3_protein" title="14-3-3 protein">14-3-3</a> <ul><li><a href="/wiki/YWHAE" title="YWHAE">YWHAE</a></li> <li><a href="/wiki/YWHAZ" title="YWHAZ">YWHAZ</a></li></ul></li> <li><a href="/wiki/Caveolin" title="Caveolin">Caveolin</a></li> <li><a href="/wiki/Cortactin" title="Cortactin">Cortactin</a></li> <li><a href="/wiki/Death-inducing_signaling_complex" title="Death-inducing signaling complex">Death-inducing signaling complex</a></li> <li><a href="/wiki/Paxillin" title="Paxillin">Paxillin</a></li> <li><a href="/wiki/MYD88" title="MYD88">MYD88</a></li> <li><a href="/wiki/SMAD_(protein)" title="SMAD (protein)">SMAD</a></li> <li><a href="/wiki/TNF_receptor_associated_factor" title="TNF receptor associated factor">TRAF</a> <ul><li><a href="/wiki/TRAF1" title="TRAF1">TRAF1</a></li> <li><a href="/wiki/TRAF2" title="TRAF2">TRAF2</a></li> <li><a href="/wiki/TRAF3" title="TRAF3">TRAF3</a></li> <li><a href="/wiki/TRAF4" title="TRAF4">TRAF4</a></li> <li><a href="/wiki/TRAF5" title="TRAF5">TRAF5</a></li> <li><a href="/wiki/TRAF6" title="TRAF6">TRAF6</a>)</li></ul></li> <li><a href="/wiki/BIN1" title="BIN1">BIN1</a></li> <li><a href="/wiki/SH3BP2" title="SH3BP2">SH3BP2</a></li> <li><a class="mw-selflink selflink">LDB3</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Rab_escort_protein" class="mw-redirect" title="Rab escort protein">CHM</a></li> <li><a href="/wiki/CHML_(gene)" title="CHML (gene)">CHML</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <p><i>This article incorporates text from the <a href="/wiki/United_States_National_Library_of_Medicine" title="United States National Library of Medicine">United States National Library of Medicine</a>, which is in the <a href="/wiki/Public_domain" title="Public domain">public domain</a>.</i> </p>    </div><noscript><img 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