Up-to-date knowledge about analytical methods for homocysteine thiolactone determination in biological samples

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ANALYTICAL CHEMISTRY </a> </h5> <span> 卷 159, 期 -, 页码 - </span> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">出版社</h4> <div class="f16"> <h5 class="title f16 text-primary"> ELSEVIER SCI LTD </h5> <div class="my-2"> DOI: 10.1016/j.trac.2022.116906 </div> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">关键词</h4> <div class="f16"> Capillary electrophoresis; Deproteinization; Derivatization; Extraction; Gas chromatography; Homocysteine thiolactone; Liquid chromatography; Plasma; Saliva; Urine </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">类别</h4> <div class="f16"> <span class="d-block"> <a href="https://www.peeref.com/zh/works/list?category=Chemistry%2C+Analytical" target="_blank" class="text-dark btn btn-link p-0 text-left"> Chemistry, Analytical </a> </span> </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 text-center">向作者/读者索取更多资源</h4> <div class="requests"> <div class="requests-item"> <div class="icon"> <img 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class="tab-content border border-top-0"> <div id="ai_summary" class="tab-pane active"> <div class="summary-panel panel-box mb-0 rounded shadow-none"> <div class="f16">This overview summarizes all documented analytical methods for the quantification of homocysteine thiolactone (HTL) in biological samples, with a focus on pre-analytical treatment strategies and separation techniques. The review also discusses the advantages, pitfalls, and limitations of the methods, as well as the origin and main metabolites of HTL, and the association between civilization diseases and sulfur-containing compounds' metabolism disorders.</div> </div> </div> <div id="raw_abstract" class="tab-pane "> <div class="abstract-panel panel-box mb-0 rounded shadow-none"> <div class="f16">Over twenty-years clinical studies have established that homocysteine thiolactone (HTL) is involved in a number of health disorders, including civilization diseases. Nevertheless, the role of HTL in health and disease is not fully understood. So far, HTL presence have been documented in humans and a number of variety animals' plasma, urine and saliva. Despite this fact, its quantification in biological samples still remains challenging. This overview summarizes all documented analytical methods that can be used for quantification of HTL in biological samples. In particular, work focuses on pre-analytical treatment strategies and assays based on separation techniques that were applied to samples of clinical importance. Some experimental details of all analytical procedures are reviewed. Moreover, advantages, pitfalls and limitations of all mentioned methods are discussed. It also outlines the origin of HTL and its main me-tabolites, and an association between civilization diseases and sulfur-containing compounds' metabolism disorders as these subjects have been already covered in great details in numerous excellent papers. Hopefully, the review which is addressed to early stage and experienced scientist, will stimulate further interest in the field.(c) 2022 Elsevier B.V. All rights reserved.</div> </div> </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">作者</h4> <div class="mb-3"> <article-authors tid="26749436" list="[{"name":"Justyna Piechocka","sequence":1},{"name":"Rafal Glowacki","sequence":2}]" verified="[]" page="work" ></article-authors> </div> <div class="alert alert-warning mb-0"> <h5 class="mt-0 bg-warning text-dark px-3 rounded d-inline-block"> 我是这篇论文的作者 </h5> <div class="font-weight-bold f13"> 点击您的名字以认领此论文并将其添加到您的个人资料中。 </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">评论</h4> <div class="d-flex flex-wrap flex-md-nowrap"> <div class="flex-grow-1"> <h4 class="f16"> 主要评分 <a href="javascript:;" data-toggle="tooltip" data-placement="right" title="主要评分表示论文的整体质量水平。"> <i class="ivu-icon ivu-icon-md-help-circle f18 ml-2"></i> </a> </h4> <div class="d-flex flex-wrap flex-md-nowrap align-items-center alert mb-0"> <div class="d-flex align-items-center justify-content-center"> <Rate disabled allow-half value="4.7" style="font-size: 28px;"></Rate> <strong class="f20 m-3" style="color: #f5a623;">4.7</strong> </div> <div class="text-muted mx-4"> 评分不足 </div> </div> <h4 class="f16"> 次要评分 <a href="javascript:;" data-toggle="tooltip" data-placement="right" title="次要评分独立反映论文的优点或缺点。"> <i class="ivu-icon ivu-icon-md-help-circle f18 ml-2"></i> </a> </h4> <div class="d-flex flex-wrap flex-md-nowrap alert"> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">新颖性</h5> <strong class="mx-4">-</strong> </div> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">重要性</h5> <strong class="mx-4">-</strong> </div> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">科学严谨性</h5> <strong class="mx-4">-</strong> </div> </div> </div> <div class="flex-shrink-0"> <div class="border bg-light py-2 px-4"> <h5 class="mb-1">评价这篇论文</h5> <Rate class="f24" @on-change="function(value){ location.href='https://www.peeref.com/zh/works/26749436/comments?rating='+value }"></Rate> </div> </div> </div> </div> <div id="collection" class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">推荐</h4> <div class="my-3"> <ul class="nav nav-pills border-bottom pb-3" style="list-style: none; padding-left: 0;"> <li class="active"> <a href="#articles_from_related" data-toggle="tab" class="mx-0 f15"> <strong>相关</strong> </a> </li> <li class=""> <a href="#articles_from_authors" data-toggle="tab" class="mx-0 f15"> <strong>来自同一作者</strong> </a> </li> <li class=""> <a href="#articles_from_journal" data-toggle="tab" class="mx-0 f15"> <strong>来自同一期刊</strong> </a> </li> </ul> <div class="tab-content"> <div id="articles_from_related" class="tab-pane active"> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemistry & Molecular Biology </span> </div> <h4> <a href="https://www.peeref.com/zh/works/23557291" class="text-dark hover-underline">Identification and Determination of 1,3-Thiazinane-4-carboxylic Acid in Human Urine-Chromatographic Studies</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Natalia Litwicka, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/3812.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study provides evidence for the formation of the adduct 1,3-thiazinane-4-carboxylic acid (TCA) in humans through the reaction of homocysteine/thiolactone (Hcy/HTL) and formaldehyde (FA). A GC-MS method has been developed and successfully applied for the quantification of TCA in human urine samples. This method may serve as a new analytical tool for the investigation of TCA's role in living systems in routine clinical analysis. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/23557291/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/28715194" class="text-dark hover-underline">Derivatization strategies for the determination of histamine in food samples: A review of recent separation-based methods</a> </h4> <p class="text-ellipsis-2">Apostolia Tsiasioti, Constantinos K. Zacharis, Paraskevas D. Tzanavaras</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/7855.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This article reviews recent studies on the determination of histamine in food matrices using derivatization-based separation methods. The derivatization of histamine plays an important role in enhancing sensitivity, selectivity, and compatibility to analytical techniques. The article also discusses the application of the latest derivatizing reagents for histamine and various analytical techniques. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/28715194/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82127305" class="text-dark hover-underline">Comprehensive studies on the development of HPLC-MS/MS and HPLC-FL based methods for routine determination of homocysteine thiolactone in human urine</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/7745.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This report describes a new method for the determination of homocysteine thiolactone in urine, including sample pretreatment and chromatographic analysis. The method uses liquid-liquid extraction and on-column derivatization techniques, and internal standardization for quantitative analysis. The linear range of the method is 20-400 nmol/L, and the limit of quantification is 20 nmol/L, which is suitable for the screening of human urine. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TALANTA</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82127305/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Medicinal </span> </div> <h4> <a href="https://www.peeref.com/zh/works/23307453" class="text-dark hover-underline">Up-to-date studies regarding the determination of melatonin by chromatographic methods</a> </h4> <p class="text-ellipsis-2">Hussain Alessa, Amr L. Saber, Jalal T. Althakafy</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/791.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study aimed to summarize recent outcomes of chromatographic methods, such as gas chromatography and high-performance liquid chromatography, used for the determination of melatonin over the past three decades. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ARCHIV DER PHARMAZIE</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/23307453/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/34885008" class="text-dark hover-underline">Michael addition-elimination-cyclization based turn-on fluorescence (MADELCY TOF) probes for cellular cysteine imaging and estimation of blood serum cysteine and aminoacylase-1</a> </h4> <p class="text-ellipsis-2">Dastgir Shakil Shaikh, Sangeeta Parmar, Dimpy Kalia</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/513.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> Oxidative stress is a characteristic feature of various diseases, and there is a need for sensitive and technically simple methods to measure blood plasma cysteine. In this study, researchers developed a series of fluorescence probes based on Michael addition-elimination-cyclization that can selectively detect cysteine and showed rapid kinetics and excellent sensitivity. One of the probes was able to detect a biomarker for cancer and liver cirrhosis, while another probe enabled live cell imaging to monitor oxidative stress in mammalian cells. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ANALYST</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/34885008/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Multidisciplinary </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83851893" class="text-dark hover-underline">Development, cross-validation and greenness assessment of capillary electrophoresis method for determination of ALP in pharmaceutical dosage forms - an alternative to liquid chromatography</a> </h4> <p class="text-ellipsis-2">Zvonimir Mlinaric, Lu Turkovic, Ivor Babic, Tajana Silovski, Nina Kocevar Glavac, Miranda Sertic</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/8687.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> A capillary electrophoresis (CE) method for the determination of Alpelisib (ALP) in pharmaceutical dosage forms was developed and validated. The method is rapid, reliable, and can be used as an alternative technique to HPLC for the analysis of ALP in pharmaceutical dosage forms. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">RSC ADVANCES</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83851893/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/23281439" class="text-dark hover-underline">Explainable Deep Learning-Assisted Fluorescence Discrimination for Aminoglycoside Antibiotic Identification</a> </h4> <p class="text-ellipsis-2">Xiaoqing Tan, Yongpeng Liang, Yingying Ye, Zhihao Liu, Jianxin Meng, Fengyu Li</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/518.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study developed an explainable DL-assisted visualized fluorometric array-based sensing method for efficient qualitative and quantitative analysis of antibiotics. The convolutional neural network achieved high prediction accuracy and guided the improvement of the sensor array through a feedback mechanism. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ANALYTICAL CHEMISTRY</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/23281439/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/33367343" class="text-dark hover-underline">A smartphone-based gold nanoparticle colorimetric sensing platform for kanamycin detection in food samples</a> </h4> <p class="text-ellipsis-2">Ziyan Yu, Yaxiao Liao, Jie Liu, Qin Wu, Yu Cheng, Ke Huang</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/520.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> A novel colorimetric approach for detecting kanamycin based on the aggregation of gold nanoparticles (AuNPs) induced by kanamycin is presented in this study. The sensor showed a linear range of 0.5-3 nM and a limit of detection of 0.11 nM under optimal conditions. It was tested by monitoring kanamycin in six food samples with satisfactory spiked recoveries, making it a desirable choice for fast and highly sensitive detection of kanamycin. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ANALYTICAL METHODS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/33367343/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemistry & Molecular Biology </span> </div> <h4> <a href="https://www.peeref.com/zh/works/26557980" class="text-dark hover-underline">Metabolomic Profiling of Plasma, Urine, and Saliva of Kidney Transplantation Recipients</a> </h4> <p class="text-ellipsis-2">Hitoshi Iwamoto, Masaaki Okihara, Isao Akashi, Yu Kihara, Osamu Konno, Shigeyuki Kawachi, Makoto Sunamura, Masahiro Sugimoto</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/3812.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> Kidney biopsy is commonly used to diagnose kidney transplant dysfunction. In this study, capillary electrophoresis-mass spectrometry was used to analyze the biofluids of transplant recipients. Metabolomics analyses revealed significant differences in the metabolomic profiles of the different groups, particularly in arginine biosynthesis and purine metabolism in plasma samples. Different types of kidney disorders also showed distinct metabolomic profiles. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/26557980/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/26657253" class="text-dark hover-underline">On-line solid-phase extraction to enhance sensitivity in peptide biomarker analysis by microseparation techniques coupled to mass spectrometry: Capillary liquid chromatography versus capillary electrophoresis</a> </h4> <p class="text-ellipsis-2">Oumaima El Ouahabi, Montserrat Mancera-Arteu, Laura Pont, Estela Gimenez, Victoria Sanz-Nebot, Fernando Benavente</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/5871.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study compared the analysis of opioid peptides using on-line solid-phase extraction capillary liquid chromatography-mass spectrometry (SPE-CapLC-MS) and on-line solid-phase extraction capillary electrophoresis-mass spectrometry (SPE-CE-MS). The SPE-CapLC-MS method showed improved detection limits and sensitivity compared to the CapLC-MS method. A comparison with the valve-free C18-SPE-CE-MS method revealed noticeable differences in operation and instrumental setup. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">MICROCHEMICAL JOURNAL</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/26657253/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/zh/works/27697507" class="text-dark hover-underline">Simultaneous determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid and main plasma aminothiols by HPLC-UV based method</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Monika Wyszczelska-Rokiel, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/8695.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This report presents a method for simultaneous determination of plasma HPPTCA and total low molecular-weight thiols content. The assay is based on HPLC-UV, involving disulfides reduction, derivatization, and sample deproteinization. The HPLC-UV assay provides a complementary tool for routine clinical analysis and facilitates further studies on the role of aminothiols and HPPTCA in living systems. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">SCIENTIFIC REPORTS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/27697507/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/zh/works/28469147" class="text-dark hover-underline">One-pot sample preparation procedure for the determination of protein N-linked homocysteine by HPLC-FLD based method</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/4298.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> The report introduces a robust and high throughput method, HPLC-FLD, for determining total protein N-linked homocysteine (Hcy) in human plasma. The method involves precipitation and removal of other forms of Hcy, reduction and wash, followed by hydrolysis, drying, and reconstitution. The resulting Hcy-thiolactone is separated using isocratic elution on PolymerX RP-1 column within 3 minutes. The method is quantified by fluorescence detection and successfully applied to plasma samples. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/28469147/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/27172300" class="text-dark hover-underline">Light-Up Aptameric Sensor of Serotonin for Point-of-Care Use</a> </h4> <p class="text-ellipsis-2">Gege Song, Zhiqiao Zou, Ailing Feng, Chenbiao Li, Meijuan Liang, Fuan Wang, Xiaoqing Liu</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/518.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> In this study, a flexible and portable light-up aptameric sensor was developed for smartphone-based point-of-care testing. By manipulating the affinity and dynamic response of designer DNA molecules, detection of serotonin was achieved with high sensitivity and selectivity. The study also demonstrated the versatility of the engineered aptameric molecular probes for different sensing applications. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ANALYTICAL CHEMISTRY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/27172300/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/33716159" class="text-dark hover-underline">Sequential speciation analysis of heavy metals on suspended particulate matter in water using electrochemical mass spectrometry</a> </h4> <p class="text-ellipsis-2">Xinglei Zhang, Yuan Xu, Ting Li, Hui Li, Zhendong Yu, Lili Song, Jiaquan Xu</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/4114.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> In this study, electrochemical mass spectrometry (EC-MS) combined with in situ electrospray ionization mass spectrometry (ESI-MS) was used to directly analyze heavy metal speciations in suspended particulate matter (SPM) in water. Four types of speciations were obtained through water and methanol extraction and sequential extraction. Compared with traditional methods, this method has the advantages of no complex matrix separation process, less sample consumption, and high analysis throughput, making it suitable for advanced applications in environmental monitoring and risk assessment. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/33716159/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/26745830" class="text-dark hover-underline">Hyphenation of Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) with separation methods: The art of compromises and the possible-A review</a> </h4> <p class="text-ellipsis-2">Clarisse Gosset-Erard, Frederic Aubriet, Emmanuelle Leize-Wagner, Yannis-Nicolas Francois, Patrick Chaimbault</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/7745.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This review provides an overview of the online hyphenation of FT-ICR MS with separation methods, highlighting its advantages and challenges. While FT-ICR MS requires time to achieve high resolving power and accuracy, chromatography and electrophoresis offer transient peaks. The combination of these techniques balances their strengths and weaknesses, making it valuable for applications such as untargeted Omics. Although implementing FT-ICR MS with online separation methods can be challenging, it has shown unparalleled results and raises questions about its future with advancing technology. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TALANTA</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/26745830/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> </div> <div id="articles_from_authors" class="tab-pane "> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82127305" class="text-dark hover-underline">Comprehensive studies on the development of HPLC-MS/MS and HPLC-FL based methods for routine determination of homocysteine thiolactone in human urine</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This report describes a new method for the determination of homocysteine thiolactone in urine, including sample pretreatment and chromatographic analysis. The method uses liquid-liquid extraction and on-column derivatization techniques, and internal standardization for quantitative analysis. The linear range of the method is 20-400 nmol/L, and the limit of quantification is 20 nmol/L, which is suitable for the screening of human urine. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TALANTA</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82127305/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83746217" class="text-dark hover-underline">Homocysteine thiolactone and other sulfur-containing amino acid metabolites are associated with fibrin clot properties and the risk of ischemic stroke</a> </h4> <p class="text-ellipsis-2">Marta Sikora, Ewa Bretes, Joanna Perla-Kajan, Olga Utyro, Kamila Borowczyk, Justyna Piechocka, Rafal Glowacki, Izabela Wojtasz, Radoslaw Kazmierski, Hieronim Jakubowski</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study analyzed plasma and urine from stroke patients and healthy individuals, finding significant differences in sulfur-containing amino acid metabolite levels and fibrin clot properties. Fibrin CLT was correlated with fibrin Abs(max) in healthy individuals, but not in stroke patients. Multiple regression analysis showed that various factors were associated with fibrin Abs(max) and fibrin CLT in stroke patients. Logistic regression analysis indicated that uHTL, uHcy, pCysGly, pGSH, MTHFR C677T polymorphism, and Abs(max) were independently associated with stroke. The results suggest that HTL and other sulfur-containing amino acid metabolites may influence fibrin clot properties and the risk of stroke. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">SCIENTIFIC REPORTS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83746217/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/zh/works/84341255" class="text-dark hover-underline">HPLC-MS/MS based method for the determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid in human plasma</a> </h4> <p class="text-ellipsis-2">Marta Gawel, Rafal Glowacki, Pawel Kubalczyk, Justyna Piechocka</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> The report describes an HPLC-MS/MS method for determining HPPTCA in plasma, using 4-DPD as an internal standard. The sample preparation involves ACN extraction, ultrafiltration, and dilution with the mobile phase. The chromatographic separation is completed within 6 minutes, with a linear range of 0.25-10 μmol/L and a quantification limit of 0.25 μmol/L. The method has been successfully applied to plasma sample screening, and HPPTCA was detected in eleven of the fifteen study samples, with a concentration range of 0.55 to 8.39 μmol/L. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">SCIENTIFIC REPORTS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/84341255/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/zh/works/28469147" class="text-dark hover-underline">One-pot sample preparation procedure for the determination of protein N-linked homocysteine by HPLC-FLD based method</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> The report introduces a robust and high throughput method, HPLC-FLD, for determining total protein N-linked homocysteine (Hcy) in human plasma. The method involves precipitation and removal of other forms of Hcy, reduction and wash, followed by hydrolysis, drying, and reconstitution. The resulting Hcy-thiolactone is separated using isocratic elution on PolymerX RP-1 column within 3 minutes. The method is quantified by fluorescence detection and successfully applied to plasma samples. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/28469147/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Endocrinology & Metabolism </span> </div> <h4> <a href="https://www.peeref.com/zh/works/28591658" class="text-dark hover-underline">p Plasma thiol levels and methylenetetrahydrofolate reductase gene c.665C > T and c.1286A > C variants affect fibrin clot properties in Polish venous thromboembolic patients</a> </h4> <p class="text-ellipsis-2">Adrianna Klajmon, Rafal Glowacki, Justyna Piechocka, Piotr Kopinski, Michal Zabczyk, Joanna Natorska</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study investigates the associations between 5,10-methylenetetrahy-drofolate reductase (MTHFR) gene variants and oxidative stress indicators as well as fibrin clot properties in patients with venous thromboembolism (VTE). The results show that patients with MTHFR variants and high total homocysteine (tHcy) levels have elevated levels of cysteine (Cys) and nitrotyrosine, which are associated with prothrombotic fibrin clot properties. Furthermore, the study finds correlations between oxidative stress indicators and fibrin clot properties in MTHFR variant carriers. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">MOLECULAR GENETICS AND METABOLISM</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/28591658/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/zh/works/27697507" class="text-dark hover-underline">Simultaneous determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid and main plasma aminothiols by HPLC-UV based method</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Monika Wyszczelska-Rokiel, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This report presents a method for simultaneous determination of plasma HPPTCA and total low molecular-weight thiols content. The assay is based on HPLC-UV, involving disulfides reduction, derivatization, and sample deproteinization. The HPLC-UV assay provides a complementary tool for routine clinical analysis and facilitates further studies on the role of aminothiols and HPPTCA in living systems. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">SCIENTIFIC REPORTS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/27697507/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82708326" class="text-dark hover-underline">Application of the HPLC-ELSD technique for the determination of major metabolites of ibuprofen and creatinine in human urine</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Natalia Matwiej, Marta Gawel, Michal Matyjaszczyk, Rafal Glowacki, Grazyna Chwatko</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This report presents a method based on HPLC-ELSD for the simultaneous determination of ibuprofen metabolites and creatinine in human urine. The method is simple, rapid, and accurate, and suitable for human urine screening. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">SCIENTIFIC REPORTS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82708326/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemistry & Molecular Biology </span> </div> <h4> <a href="https://www.peeref.com/zh/works/23557291" class="text-dark hover-underline">Identification and Determination of 1,3-Thiazinane-4-carboxylic Acid in Human Urine-Chromatographic Studies</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Natalia Litwicka, Rafal Glowacki</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study provides evidence for the formation of the adduct 1,3-thiazinane-4-carboxylic acid (TCA) in humans through the reaction of homocysteine/thiolactone (Hcy/HTL) and formaldehyde (FA). A GC-MS method has been developed and successfully applied for the quantification of TCA in human urine samples. This method may serve as a new analytical tool for the investigation of TCA's role in living systems in routine clinical analysis. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/23557291/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Polymer Science </span> </div> <h4> <a href="https://www.peeref.com/zh/works/24822572" class="text-dark hover-underline">Small molecule diffusion in poly-(olygo ethylene glycol methacrylate) based hydrogels studied by fluorescence correlation spectroscopy</a> </h4> <p class="text-ellipsis-2">Krzysztof Piechocki, Kaloian Koynov, Justyna Piechocka, Kordian Chamerski, Jacek Filipecki, Paulina Maczugowska, Marcin Kozanecki</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> Understanding the diffusion of solutes in hydrogels is crucial for developing applications, and this study investigated the influence of structural parameters on diffusion in POEGMAs hydrogels. FCS was used to analyze the diffusion process, revealing two components attributed to steric effects and interactions with the polymer. The relationship between diffusion and polymer concentration showed two regimes, influenced by hydrophilicity/hydrophobicity and cross-links. The release time of a model drug was found to be shorter in denser hydrogel networks, indicating the importance of drug affinity over diffusion. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">POLYMER</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/24822572/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemistry & Molecular Biology </span> </div> <h4> <a href="https://www.peeref.com/zh/works/26009822" class="text-dark hover-underline">Organic Acids Secreted by Lactobacillus spp. Isolated from Urine and Their Antimicrobial Activity against Uropathogenic Proteus mirabilis</a> </h4> <p class="text-ellipsis-2">Dominika Szczerbiec, Justyna Piechocka, Rafal Glowacki, Agnieszka Torzewska</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This study investigates the antibacterial effect of organic acids secreted by Lactobacillus strains on urinary tract infections caused by P. mirabilis. The results show that these acids have a high inhibitory effect on the growth and biofilm formation of P. mirabilis and could be used as novel agents for the treatment of urinary tract infections. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">MOLECULES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/26009822/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Engineering, Environmental </span> </div> <h4> <a href="https://www.peeref.com/zh/works/22605471" class="text-dark hover-underline">Microalgae-based removal of contaminants of emerging concern: Mechanisms in Chlorella vulgaris and mixed algal-bacterial cultures</a> </h4> <p class="text-ellipsis-2">Franja Prosenc, Justyna Piechocka, David Skufca, Ester Heath, Tjasa Griessler Bulc, Darja Istenic, Gianluigi Buttiglieri</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> The study found that a mixed microalgal-bacterial culture was more effective in removing bisphenols compared to Chlorella vulgaris; bisphenols with high log K-ow were mainly removed abiotically, while those with lower log K-ow were biodegraded; the removal efficiency and pathways of pharmaceuticals and EU Watch List substances were comparable in both cultures. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF HAZARDOUS MATERIALS</span> (2021) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/22605471/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemistry & Molecular Biology </span> </div> <h4> <a href="https://www.peeref.com/zh/works/20172309" class="text-dark hover-underline">2-(3-Hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic Acid, Novel Metabolite of Pyridoxal 5′-Phosphate and Cysteine Is Present in Human Plasma-Chromatographic Investigations</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Monika Wronska, Iwona E. Glowacka, Rafal Glowacki</p> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> (2020) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/20172309/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/20339241" class="text-dark hover-underline">Chromatographic strategies for the determination of aminothiols in human saliva</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Monika Wronska, Rafal Glowacki</p> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2020) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/20339241/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/zh/works/20610102" class="text-dark hover-underline">Quantification of homocysteine thiolactone in human saliva and urine by gas chromatography-mass spectrometry</a> </h4> <p class="text-ellipsis-2">Justyna Piechocka, Monika Wronska, Grazyna Chwatko, Hieronim Jakubowski, Rafal Glowacki</p> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES</span> (2020) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/20610102/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> </div> <div id="articles_from_journal" class="tab-pane "> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83108604" class="text-dark hover-underline">Optical biosensors for the detection of foodborne pathogens: recent development and future prospects</a> </h4> <p class="text-ellipsis-2">Yuhe Wang, Kaiyuan Jia, Jianhan Lin</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This paper reviews the basic principles of optical biosensors and discusses the key issues in the application of foodborne pathogen detection, such as sample collection, pathogen isolation and pathogen detection. In addition, the latest progress of optical biosensors, including SPR biosensors, interference biosensors, SERS biosensors, fluorescence biosensors, chemiluminescence biosensors and colorimetry biosensors, is reviewed. More importantly, the latest research and development trends of optical biosensors for the detection of foodborne pathogens are summarized. This paper can provide a comprehensive reference for the development of optical biosensors for the detection of foodborne pathogens. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83108604/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83083968" class="text-dark hover-underline">A review on the occurrence, detection methods, and ecotoxicity of biodegradable microplastics in the aquatic environment: New cause for concern</a> </h4> <p class="text-ellipsis-2">Chaoli Shi, Yinan Zhang, Yongjian Shao, Suprakas Sinha Ray, Bingyi Wang, Zirui Zhao, Bingzhi Yu, Xiaofang Zhang, Wenbing Li, Jiafeng Ding, Zhiquan Liu, Hangjun Zhang</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This article introduces the application of biodegradable plastics in alleviating microplastic pollution, and points out that their incomplete degradation will produce microplastics and may persist in the environment. The article also discusses the concentration, detection methods, and adverse effects of biodegradable microplastics in the aquatic environment, and emphasizes the need to re-evaluate their use, disposal, and management strategies. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83083968/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82989031" class="text-dark hover-underline">Advances and challenges of signal readout systems in CRISPR-based biosensors for point-of-care testing of nucleic acid</a> </h4> <p class="text-ellipsis-2">Di Huang, Chutian Xu, Chenhang Jiang, Qixing Chen, Zhinan Xu, Xiangming Fang</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> CRISPR systems are promising in nucleic acid POCT, but face challenges. Integrating portable signal readout methods with CRISPR systems shows potential. The review introduces Cas nucleases, summarizes signal readout systems of CRISPR-based biosensors, and proposes challenges and prospects. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82989031/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83167395" class="text-dark hover-underline">Recent advances on nanozyme-based electrochemical biosensors for cancer biomarker detection</a> </h4> <p class="text-ellipsis-2">Annadurai Thamilselvan, Moon Il Kim</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This article introduces the application of nanozymes in electrochemical biosensors, especially in the research progress of cancer biomarker detection. The working mechanism of nanozymes and their role as signal/amplification tags or catalysts are discussed, as well as the application of traditional nanozymes and emerging nanozymes. Current challenges and future development directions are also explored. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83167395/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83167333" class="text-dark hover-underline">CRISPR/Cas biosensing technology: From lab assays to integrated portable devices towards wearables</a> </h4> <p class="text-ellipsis-2">Ruya Shi, Ling Zhong, Guozhen Liu, Wing Cheung Mak</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> The CRISPR system shows great potential in life science and bioengineering, but challenges remain in developing integrated biosensing devices for POC applications. This review summarizes the development of CRISPR/Cas biosensing systems, including the transition from lab assays to portable devices, and the benefits of different biosensing platforms. The article aims to promote the combination of CRISPR/Cas technology with advanced biosensing platforms for POC health monitoring and other fields. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83167333/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82989073" class="text-dark hover-underline">Engineering metal-organic frameworks-based nanozymes for enhanced biomimetic catalytic sensing</a> </h4> <p class="text-ellipsis-2">Zhong Wei Jiang, Xue Gong, Yi Wang, Yuan Fang Li, Cheng Zhi Huang</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This paper introduces the advantages and development obstacles of nanozymes, and points out that MOFs-based nanozymes have been widely developed due to their unique structure and customizability. The article also summarizes the activity regulatory strategies and applications in biosensing of MOFs-based nanozymes, and puts forward the current challenges and future development directions. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82989073/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83057811" class="text-dark hover-underline">The metal- and covalent-organic frameworks-based molecularly imprinted polymer composites for sample pretreatment</a> </h4> <p class="text-ellipsis-2">Yuhao Wen, Dani Sun, Jinhua Li, Abbas Ostovan, Xiaoyan Wang, Jiping Ma, Jinmao You, Turghun Muhammad, Lingxin Chen, Maryam Arabi</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This review discusses the use of sorbents with specific structures and recognition abilities in analytical methods, focusing on the development of sample pretreatment techniques based on molecularly imprinted polymers (MIPs). The article discusses the problems of traditional MIPs and introduces solutions by integrating MIPs with functional materials. The review also summarizes the application progress of MOFs- and COFs-based MIPs composites in sample pretreatment techniques and prospects their future development. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83057811/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82949245" class="text-dark hover-underline">Recent advances and applications of novel advanced materials in solid-phase microextraction for natural products</a> </h4> <p class="text-ellipsis-2">Huang-Fei Jin, Ying Shi, Jun Cao</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This article discusses the issue of toxic component contamination in the quality control of natural products, introduces solid-phase microextraction technology and its improvements, reviews the applications of various extractants in solid-phase microextraction for the extraction and separation of active and toxic components in natural products from 2018 to 2023, and finally summarizes the prospects and future trends. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82949245/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83548840" class="text-dark hover-underline">Electronic nose for the detection and discrimination of volatile organic compounds: Application, challenges, and perspectives</a> </h4> <p class="text-ellipsis-2">Yanchen Li, Zike Wang, Tianning Zhao, Hua Li, Jingkun Jiang, Jianhuai Ye</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This article reviews the advancements in e-nose technology for the detection of volatile organic compounds (VOCs). The operational principles of various sensors and their strengths and weaknesses are detailed, and the algorithms for VOC pattern recognition are discussed, emphasizing their role in enhancing detection accuracy and application robustness. The applications of e-noses in environmental monitoring, food processing, and medical diagnostics are also explored, and the current challenges in e-nose applications, such as selectivity and sensitivity, are addressed. Insights into emerging trends and future perspectives in e-nose development are provided. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83548840/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/82967671" class="text-dark hover-underline">Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches</a> </h4> <p class="text-ellipsis-2">Bingshen Liu, Zenan Shen, Qian Zhou, Lingling Hu, Ganning Zeng, Xiaonan Wang, Ming Zhang, Daoyong Zhang, Xiangliang Pan</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This paper reviews the current state of research on MPs in soil aggregates, including analytical methods, occurrence patterns, ecological impacts, and biodegradation. Studies show that aggregates are hotspots for MPs pollution, but current research methods and concentration settings have problems. Microbial degradation of MPs has potential, but further research is needed. Future research should focus on innovative analytical methods to reveal the fate and behavior of MPs in aggregates. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/82967671/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83063637" class="text-dark hover-underline">Microplastics in urban stormwater sediments and runoff: An essential component in the microplastic cycle</a> </h4> <p class="text-ellipsis-2">Madushika Sewwandi, Abhishek Kumar, Shiran Pallewatta, Meththika Vithanage</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This review summarizes the characteristics of microplastics in urban stormwater runoff, including abundance, morphology, color, and size, and suggests future research directions. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83063637/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83733427" class="text-dark hover-underline">Near infrared quantum dots for biosensing and bioimaging</a> </h4> <p class="text-ellipsis-2">K. David Wegner, Niko Hildebrandt</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> Quantum dots have unique optoelectronic properties, making them attractive as optical probes in biosensing and bioimaging. Near-infrared emitting QDs reduce scattering, absorption, and autofluorescence of biological components, increasing light penetration depth and resolution. The field is growing rapidly, and the benefits of using QDs have been demonstrated in various applications. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83733427/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/84306292" class="text-dark hover-underline">Recent advances in flexible sensors: From sensing materials to detection modes</a> </h4> <p class="text-ellipsis-2">Jiao Qin, Yuxin Tang, Yongyi Zeng, Xiaolong Liu, Dianping Tang</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This paper reviews the recent progress of flexible sensors, including sensing materials and detection modes. Different types of sensing materials are introduced, and various detection modes of flexible sensors are summarized. The challenges and solutions in practical applications are also discussed. The potential and innovation of flexible sensors are emphasized. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/84306292/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83114227" class="text-dark hover-underline">A critical review of the analytical performance of the most recent MOS-based gas sensors for indoor air quality monitoring of WHO priority pollutants</a> </h4> <p class="text-ellipsis-2">M. I. S. Verissimo</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> In the past few years, sensors for indoor air quality monitoring have developed rapidly. Their miniaturization, low cost, and importance to human health have made them increasingly concerned. Metal oxide semiconductor gas sensors have overcome some challenges and can now detect some of the WHO's priority target gases at room temperature, reaching safety standards. Although there are still problems to be solved, the progress in this field is encouraging. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83114227/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Chemistry, Analytical </span> </div> <h4> <a href="https://www.peeref.com/zh/works/83028199" class="text-dark hover-underline">Human exposure to micro(nano)plastics: Health risks and analysis methods</a> </h4> <p class="text-ellipsis-2">Guoyou Chen, Xiaolei Li, Zhibin Wang, Minghui Li, Wenyi Wang, Ruize Lu, Shihe Wang, Qi Li, Zunbo Hu, Yanwen Wu, Zhonghua Li, Peng Wang, Yonggang Cao</p> <div class="d-flex mb-3"> <div class="p-3 rounded bg-light-blue"> <strong>Summary:</strong> This article focuses on the impact of micro (nano) plastic pollution on the ecosystem and human health, introduces its effects on biological tissues and detection methods, and emphasizes the significance of further research. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">TRAC-TRENDS IN ANALYTICAL CHEMISTRY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/zh/works/83028199/add-to-collection" target="_blank"> <strong>添加到收藏夹</strong> </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="modal fade" id="export-citation" tabindex="-1"> <div class="modal-dialog"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal"><span>×</span></button> <h4 class="modal-title">导出引文 <b 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Up-to-date knowledge about analytical methods for homocysteine thiolactone determination in biological samples - Peeref