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href="/w/index.php?title=Special:%E5%88%9B%E5%BB%BA%E8%B4%A6%E6%88%B7&returnto=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" title="我们推荐您创建账号并登录，但这不是强制性的" class=""><span>创建账号</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:%E7%94%A8%E6%88%B7%E7%99%BB%E5%BD%95&returnto=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" title="建议你登录，尽管并非必须。[o]" accesskey="o" class=""><span>登录</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="更多选项" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="个人工具" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">个人工具</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="用户菜单" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=zh.wikipedia.org&uselang=zh"><span>资助维基百科</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E5%88%9B%E5%BB%BA%E8%B4%A6%E6%88%B7&returnto=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" title="我们推荐您创建账号并登录，但这不是强制性的"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>创建账号</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E7%94%A8%E6%88%B7%E7%99%BB%E5%BD%95&returnto=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" title="建议你登录，尽管并非必须。[o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>登录</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> 未登录编辑者的页面 <a href="/wiki/Help:%E6%96%B0%E6%89%8B%E5%85%A5%E9%97%A8" aria-label="了解有关编辑的更多信息"><span>了解详情</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li 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vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目录</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">隐藏</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">序言</div> </a> </li> <li id="toc-早年生活和教育" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#早年生活和教育"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>早年生活和教育</span> </div> </a> <ul id="toc-早年生活和教育-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-职业生涯与研究" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#职业生涯与研究"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>职业生涯与研究</span> </div> </a> <button aria-controls="toc-职业生涯与研究-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>开关职业生涯与研究子章节</span> </button> <ul id="toc-职业生涯与研究-sublist" class="vector-toc-list"> <li id="toc-Southern印迹法" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Southern印迹法"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Southern印迹法</span> </div> </a> <ul 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class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">埃德温·萨瑟恩</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。11种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-11" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">11种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Edwin_Southern" title="Edwin Southern – 南非荷兰语" lang="af" hreflang="af" data-title="Edwin Southern" data-language-autonym="Afrikaans" data-language-local-name="南非荷兰语" class="interlanguage-link-target"><span>Afrikaans</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%A7%D8%AF%D9%88%DB%8C%D9%86_%D8%B3%D8%A7%D9%88%D8%AA%D8%B1%D9%86" title="ادوین ساوترن – South Azerbaijani" lang="azb" hreflang="azb" data-title="ادوین ساوترن" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Edwin_Southern" title="Edwin Southern – 德语" lang="de" hreflang="de" data-title="Edwin Southern" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Edwin_Southern" title="Edwin Southern – 英语" lang="en" hreflang="en" data-title="Edwin Southern" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%D8%AF%D9%88%DB%8C%D9%86_%D8%B3%D8%A7%D9%88%D8%AA%D8%B1%D9%86" title="ادوین ساوترن – 波斯语" lang="fa" hreflang="fa" data-title="ادوین ساوترن" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Edwin_Southern" title="Edwin Southern – 法语" lang="fr" hreflang="fr" data-title="Edwin Southern" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Edwin_Mellor_Southern" title="Edwin Mellor Southern – 意大利语" lang="it" hreflang="it" data-title="Edwin Mellor Southern" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A8%E3%83%89%E3%82%A6%E3%82%A3%E3%83%B3%E3%83%BB%E3%82%B5%E3%82%B6%E3%83%B3" title="エドウィン・サザン – 日语" lang="ja" hreflang="ja" data-title="エドウィン・サザン" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Edwin_Southern" title="Edwin Southern – 葡萄牙语" lang="pt" hreflang="pt" data-title="Edwin Southern" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A1%D0%B0%D1%83%D0%B7%D0%B5%D1%80%D0%BD,_%D0%AD%D0%B4%D0%B2%D0%B8%D0%BD" title="Саузерн, Эдвин – 俄语" lang="ru" hreflang="ru" data-title="Саузерн, Эдвин" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Edwin_Southern" title="Edwin Southern – 瑞典语" lang="sv" hreflang="sv" data-title="Edwin Southern" data-language-autonym="Svenska" data-language-local-name="瑞典语" class="interlanguage-link-target"><span>Svenska</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q903388#sitelinks-wikipedia" title="编辑跨语言链接" class="wbc-editpage">编辑链接</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="命名空间"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" title="浏览条目正文[c]" accesskey="c"><span>条目</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" rel="discussion" title="关于此页面的讨论[t]" accesskey="t"><span>讨论</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="更改语言变体" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">不转换</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-varlang-0" class="selected ca-variants-zh mw-list-item"><a href="/zh/%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9" lang="zh" hreflang="zh"><span>不转换</span></a></li><li id="ca-varlang-1" class="ca-variants-zh-Hans mw-list-item"><a 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.navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox biography vcard"><tbody><tr><th colspan="2" class="infobox-above"><span class="fn">Sir Edwin Southern</span><br /><span class="honorific-suffix" style="font-size: small; font-weight: normal"><span style="font-size:100%;"><a href="/wiki/%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A%E9%99%A2%E5%A3%AB" title="皇家学会院士">FRS</a> <a href="/wiki/%E7%88%B1%E4%B8%81%E5%A0%A1%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A" title="爱丁堡皇家学会">FRSE</a></span></span></th></tr><tr><td colspan="2" class="infobox-image"><span typeof="mw:File"><a href="/wiki/File:Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png/200px-Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png" decoding="async" width="200" height="246" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png/300px-Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png/400px-Edwin_Mellor_Southern_-_journal.pgen.1003344.g001.png 2x" data-file-width="1329" data-file-height="1637" /></a></span><div class="infobox-caption">Sir Edwin in 2012</div></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;;">出生</th><td class="infobox-data" style=""><span class="nickname">Edwin Mellor Southern</span><br /><span style="display:none"> (<span class="bday">1938-06-07</span>) </span>1938年6月7日<span class="noprint ForceAgeToShow">（<span class="currentage"></span>86歲）</span><sup id="cite_ref-cv_3-0" class="reference"><a href="#cite_note-cv-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><br /><span class="birthplace"><a href="/wiki/%E4%BC%AF%E6%81%A9%E5%88%A9" title="伯恩利">伯恩利</a>, United Kingdom</span></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;;">国籍</th><td class="infobox-data category" style="">British</td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;;">母校</th><td class="infobox-data" style=""><style data-mw-deduplicate="TemplateStyles:r82655520">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><a href="/wiki/%E6%9B%BC%E5%BD%BB%E6%96%AF%E7%89%B9%E5%A4%A7%E5%AD%A6" title="曼彻斯特大学">曼彻斯特大学</a> (BSc) <ul><li><a href="/wiki/%E6%A0%BC%E6%8B%89%E6%96%AF%E5%93%A5%E5%A4%A7%E5%AD%A6" class="mw-redirect" title="格拉斯哥大学">格拉斯哥大学</a> (PhD)</li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;;">知名于</th><td class="infobox-data" style=""><a href="/wiki/Southern%E5%8D%B0%E8%BF%B9%E6%B3%95" class="mw-redirect" title="Southern印迹法">Southern印迹法</a></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;;">奖项</th><td class="infobox-data note" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"> <ul><li><a href="/wiki/%E7%9B%96%E5%B0%94%E5%BE%B7%E7%BA%B3%E5%9B%BD%E9%99%85%E5%A5%96" title="盖尔德纳国际奖">盖尔德纳国际奖</a> (1990)</li> <li><a href="/wiki/%E7%9A%87%E5%AE%B6%E7%8D%8E%E7%AB%A0" title="皇家獎章">皇家奖章</a> (1998)</li> <li><a href="/wiki/%E6%8B%89%E6%96%AF%E5%85%8B%E4%B8%B4%E5%BA%8A%E5%8C%BB%E5%AD%A6%E7%A0%94%E7%A9%B6%E5%A5%96" title="拉斯克临床医学研究奖">拉斯克临床医学研究奖</a> (2005)</li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;;">网站</th><td class="infobox-data url" style=""><span class="url"><a rel="nofollow" class="external text" href="http://www.ogt.co.uk/about/company/management/board_members/professor_sir_edwin_southern">www<wbr />.ogt<wbr />.co<wbr />.uk<wbr />/about<wbr />/company<wbr />/management<wbr />/board<wbr />_members<wbr />/professor<wbr />_sir<wbr />_edwin<wbr />_southern</a></span></td></tr><tr><td colspan="2" class="infobox-full-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r83732082"><b>科学生涯</b></td></tr><tr><th scope="row" class="infobox-label" style="white-space:nowrap;;">研究领域</th><td class="infobox-data category" style=""><a href="/wiki/%E5%88%86%E5%AD%90%E7%94%9F%E7%89%A9%E5%AD%A6" title="分子生物学">分子生物学</a></td></tr><tr><th scope="row" class="infobox-label" style="white-space:nowrap;;">机构</th><td class="infobox-data" style=""><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r82655520"><div class="plainlist"> <ul><li><a href="/wiki/%E7%89%9B%E6%B4%A5%E5%A4%A7%E5%AD%A6" title="牛津大学">牛津大学</a></li> <li><a href="/wiki/%E7%88%B1%E4%B8%81%E5%A0%A1%E5%A4%A7%E5%AD%A6" title="爱丁堡大学">爱丁堡大学</a></li> <li>Oxford Gene Technology<sup id="cite_ref-oxfordgene_1-0" class="reference"><a href="#cite_note-oxfordgene-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></li></ul> </div></td></tr><tr><th scope="row" class="infobox-label" style="white-space:nowrap;;"><a href="/wiki/%E8%AE%BA%E6%96%87" title="论文">论文</a></th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="http://search.proquest.com/docview/301213660">Studies on synthetic and naturally occurring enzyme metabolites</a><span style="font-size:smaller;">（1964）</span></td></tr><tr><th scope="row" class="infobox-label" style="white-space:nowrap;;">博士生</th><td class="infobox-data" style=""><span class="ilh-all" data-orig-title="Robin Allshire" data-lang-code="en" data-lang-name="英语" data-foreign-title="Robin Allshire"><span class="ilh-page"><a href="/w/index.php?title=Robin_Allshire&action=edit&redlink=1" class="new" title="Robin Allshire（页面不存在）">Robin Allshire</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Robin_Allshire" class="extiw" title="en:Robin Allshire"><span lang="en" dir="auto">Robin Allshire</span></a></span>）</span></span><sup id="cite_ref-allphd_2-0" class="reference"><a href="#cite_note-allphd-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></td></tr><tr style="display:none"><td colspan="2"> </td></tr></tbody></table> <p><b>埃德温·麦勒·萨瑟恩爵士</b> （Sir Edwin Southern，1938年6月7日<span class="useeditintro" title="Template:BLP editintro">—</span>）是英国分子生物学家，<a href="/wiki/%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A%E9%99%A2%E5%A3%AB" title="皇家学会院士">英国皇家学会院士</a>，<a href="/wiki/%E7%88%B1%E4%B8%81%E5%A0%A1%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A%E4%BC%9A%E5%91%98" title="爱丁堡皇家学会会员">爱丁堡皇家学会会员</a>，<a href="/wiki/%E6%8B%89%E6%96%AF%E5%85%8B%E5%A5%96" title="拉斯克奖">拉斯克奖</a>获得者，<a href="/wiki/%E7%89%9B%E6%B4%A5%E5%A4%A7%E5%AD%A6" title="牛津大学">牛津大学</a>生物化学名誉教授，<a href="/wiki/%E7%89%9B%E6%B4%A5%E5%A4%A7%E5%AD%A6%E4%B8%89%E4%B8%80%E5%AD%A6%E9%99%A2" title="牛津大学三一学院">牛津大学三一学院</a>研究员。<sup id="cite_ref-nature_med_2005_4-0" class="reference"><a href="#cite_note-nature_med_2005-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> 他最广为人知的发明是于1975年发表的<a href="/wiki/Southern%E5%8D%B0%E8%BF%B9%E6%B3%95" class="mw-redirect" title="Southern印迹法">Southern印迹法</a>，如今这是一项十分常用的实验室技术。<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-#1_6-0" class="reference"><a href="#cite_note-#1-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="早年生活和教育"><span id=".E6.97.A9.E5.B9.B4.E7.94.9F.E6.B4.BB.E5.92.8C.E6.95.99.E8.82.B2"></span>早年生活和教育</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&action=edit&section=1" title="编辑章节：早年生活和教育"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>萨瑟恩出生于英国<a href="/wiki/%E5%85%B0%E5%BC%80%E5%A4%8F%E9%83%A1" class="mw-redirect" title="兰开夏郡">兰开夏郡</a>的<a href="/wiki/%E4%BC%AF%E6%81%A9%E5%88%A9" title="伯恩利">伯恩利</a>，早年在伯恩利文法学校接受教育。<sup id="cite_ref-cv_3-1" class="reference"><a href="#cite_note-cv-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> 他后来在<a href="/wiki/%E6%9B%BC%E5%BD%BB%E6%96%AF%E7%89%B9%E5%A4%A7%E5%AD%A6" title="曼彻斯特大学">曼彻斯特大学</a>攻读化学，于1958年获得理学学士学位。之后，他在<a href="/wiki/%E6%A0%BC%E6%8B%89%E6%96%AF%E5%93%A5%E5%A4%A7%E5%AD%A6" class="mw-redirect" title="格拉斯哥大学">格拉斯哥大学</a>化学系攻读研究生，并于1962年获得博士学位。<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="职业生涯与研究"><span id=".E8.81.8C.E4.B8.9A.E7.94.9F.E6.B6.AF.E4.B8.8E.E7.A0.94.E7.A9.B6"></span>职业生涯与研究</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&action=edit&section=2" title="编辑章节：职业生涯与研究"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>萨瑟恩是牛津基因技术公司（Oxford Gene Technology）的创始人和主席。他还是苏格兰慈善机构，柯克豪斯信托基金会（<a href="/w/index.php?title=The_Kirkhouse_Trust&action=edit&redlink=1" class="new" title="The Kirkhouse Trust（页面不存在）">The Kirkhouse Trust</a>）的创始人和主席，其旨在促进自然科学，特别是生物和医学科学的教育和研究，而Edina信托基金会则是为了在学校推广科学而成立的。这些慈善机构的资金来自<a href="/wiki/%E5%BE%AE%E9%98%B5%E5%88%97" class="mw-redirect" title="微阵列">微阵列</a>技术的版税收入。 </p> <div class="mw-heading mw-heading3"><h3 id="Southern印迹法"><span id="Southern.E5.8D.B0.E8.BF.B9.E6.B3.95"></span>Southern印迹法</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&action=edit&section=3" title="编辑章节：Southern印迹法"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Southern%E5%8D%B0%E8%BF%B9%E6%B3%95" class="mw-redirect" title="Southern印迹法">Southern印迹法</a>是一种<a href="/wiki/%E8%84%B1%E6%B0%A7%E6%A0%B8%E7%B3%96%E6%A0%B8%E9%85%B8" title="脱氧核糖核酸">脱氧核糖核酸</a>分析技术，通常用于<a href="/wiki/%E9%81%97%E4%BC%A0%E6%8C%87%E7%BA%B9%E5%88%86%E6%9E%90" class="mw-redirect" title="遗传指纹分析">遗传指纹分析</a>，在<a href="/wiki/%E5%BE%AE%E5%8D%AB%E6%98%9F" class="mw-redirect" title="微卫星">微卫星</a>标记（microsatellite marker）技术开发之前也用于<a href="/wiki/%E4%BA%B2%E5%AD%90%E9%89%B4%E5%AE%9A" title="亲子鉴定">亲子鉴定</a>。该技术也经常用于确定<a href="/wiki/%E5%9F%BA%E5%9B%A0%E7%BB%84" class="mw-redirect" title="基因组">基因组</a>中一个基因的拷贝数。 Southern印迹的概念被用于开发和创建现代<a href="/wiki/%E5%BE%AE%E9%98%B5%E5%88%97" class="mw-redirect" title="微阵列">微阵列</a>芯片，是一种广泛使用的实验工具。而<a href="/wiki/%E5%8C%97%E6%96%B9%E5%A2%A8%E9%BB%9E%E6%B3%95" title="北方墨點法">Northern印迹法</a>、<a href="/wiki/Western%E5%8D%B0%E8%BF%B9%E6%B3%95" class="mw-redirect" title="Western印迹法">Western印迹法</a>和<a href="/w/index.php?title=Eastern%E5%8D%B0%E8%BF%B9%E6%B3%95&action=edit&redlink=1" class="new" title="Eastern印迹法（页面不存在）">Eastern印迹法</a>，分别是用于<a href="/wiki/%E6%A0%B8%E7%B3%96%E6%A0%B8%E9%85%B8" title="核糖核酸">核糖核酸</a>分析、<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8" title="蛋白质">蛋白质</a>分析和蛋白质<a href="/wiki/%E7%BF%BB%E8%AF%91%E5%90%8E%E4%BF%AE%E9%A5%B0" title="翻译后修饰">翻译后修饰</a>的相关技术，均是源于Southern名称的双关语。 </p> <div class="mw-heading mw-heading3"><h3 id="DNA微阵列"><span id="DNA.E5.BE.AE.E9.98.B5.E5.88.97"></span>DNA微阵列</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&action=edit&section=4" title="编辑章节：DNA微阵列"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>1995年，萨瑟恩创立了牛津基因技术公司（OGT），这是一家开发<a href="/wiki/DNA%E5%BE%AE%E9%98%B5%E5%88%97" class="mw-redirect" title="DNA微阵列">DNA微阵列</a>技术的公司。1999年，由于其拥有拥有微阵列技术的专利，OGT赢得了对<span class="ilh-all" data-orig-title="Affymetrix" data-lang-code="en" data-lang-name="英语" data-foreign-title="Affymetrix"><span class="ilh-page"><a href="/w/index.php?title=Affymetrix&action=edit&redlink=1" class="new" title="Affymetrix（页面不存在）">Affymetrix</a></span><span class="noprint ilh-comment">（<span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Affymetrix" class="extiw" title="en:Affymetrix"><span lang="en" dir="auto">Affymetrix</span></a></span>）</span></span>的专利侵权诉讼。<sup id="cite_ref-LancetBio_11-0" class="reference"><a href="#cite_note-LancetBio-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="奖项及荣誉"><span id=".E5.A5.96.E9.A1.B9.E5.8F.8A.E8.8D.A3.E8.AA.89"></span>奖项及荣誉</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&action=edit&section=5" title="编辑章节：奖项及荣誉"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>1990年，萨瑟恩是美国<a href="/wiki/%E7%9B%96%E5%B0%94%E5%BE%B7%E7%BA%B3%E5%9B%BD%E9%99%85%E5%A5%96" title="盖尔德纳国际奖">盖尔德纳国际奖</a>的获得者之一。<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> 1998年，他被授予<a href="/wiki/%E5%80%AB%E6%95%A6%E7%9A%87%E5%AE%B6%E5%AD%B8%E6%9C%83" class="mw-redirect" title="倫敦皇家學會">伦敦皇家学会</a><a href="/wiki/%E7%9A%87%E5%AE%B6%E7%8D%8E%E7%AB%A0" title="皇家獎章">皇家奖章</a>。<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> 2003年6月，他因为对DNA微阵列技术发展的贡献而获得<a href="/wiki/%E4%B8%8B%E7%BA%A7%E5%8B%8B%E4%BD%8D%E7%88%B5%E5%A3%AB" class="mw-redirect" title="下级勋位爵士">下级勋位爵士</a>。2005年，他与<a href="/wiki/%E8%8E%B1%E6%96%AF%E7%89%B9%E5%A4%A7%E5%AD%A6" class="mw-redirect" title="莱斯特大学">莱斯特大学</a>的<a href="/wiki/%E4%BA%9A%E5%8E%86%E5%85%8B%C2%B7%E6%9D%B0%E5%BC%97%E9%87%8C%E6%96%AF" title="亚历克·杰弗里斯">亚历克·杰弗里斯</a>因发明了 Southern印迹法共同获得了著名的<a href="/wiki/%E6%8B%89%E6%96%AF%E5%85%8B%E4%B8%B4%E5%BA%8A%E5%8C%BB%E5%AD%A6%E7%A0%94%E7%A9%B6%E5%A5%96" title="拉斯克临床医学研究奖">拉斯克临床医学研究奖</a>。<sup id="cite_ref-nature_med_20052_14-0" class="reference"><a href="#cite_note-nature_med_20052-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Lasker_acceptance_remarks_15-0" class="reference"><a href="#cite_note-Lasker_acceptance_remarks-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Lasker_2005_16-0" class="reference"><a href="#cite_note-Lasker_2005-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> 2012年，他被选为美国<a href="/wiki/%E7%88%B1%E4%B8%81%E5%A0%A1%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A" title="爱丁堡皇家学会">爱丁堡皇家学会</a>荣誉会员。<sup id="cite_ref-#1_6-1" class="reference"><a href="#cite_note-#1-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="参考资料"><span id=".E5.8F.82.E8.80.83.E8.B5.84.E6.96.99"></span>参考资料</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&action=edit&section=6" title="编辑章节：参考资料"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> <ol class="references"> <li id="cite_note-oxfordgene-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-oxfordgene_1-0">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://www.ogt.co.uk/about/company/management/board_members/professor_sir_edwin_southern">Professor Sir Edwin Southern – Founder, Chairman and Chief Science Advisor</a>. Oxford Gene Technology. <span class="reference-accessdate"> [<span class="nowrap">2019-01-16</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20150417153124/http://www.ogt.co.uk/about/company/management/board_members/professor_sir_edwin_southern">存档</a>于2015-04-17）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.btitle=Professor+Sir+Edwin+Southern+%E2%80%93+Founder%2C+Chairman+and+Chief+Science+Advisor&rft.genre=unknown&rft.pub=Oxford+Gene+Technology&rft_id=http%3A%2F%2Fwww.ogt.co.uk%2Fabout%2Fcompany%2Fmanagement%2Fboard_members%2Fprofessor_sir_edwin_southern&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-allphd-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-allphd_2-0">^</a></b></span> <span class="reference-text"><cite class="citation thesis">Allshire, Robin Campbell. <a rel="nofollow" class="external text" href="https://www.era.lib.ed.ac.uk/handle/1842/11176">Construction and analysis of vectors based on bovine papilloma virus</a>. ed.ac.uk (PhD论文) (University of Edinburgh). 1985 <span class="reference-accessdate"> [<span class="nowrap">2019-01-16</span>]</span>. <a rel="nofollow" class="external text" href="//www.worldcat.org/oclc/606010479"><span title="OCLC">OCLC 606010479</span></a>. <a rel="nofollow" class="external text" href="//hdl.handle.net/1842%2F11176"><span title="Handle System">hdl:1842/11176</span></a>. <style data-mw-deduplicate="TemplateStyles:r61200749">.mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}</style><a href="/wiki/EThOS" class="mw-redirect" title="EThOS">EThOS</a> <a rel="nofollow" class="external text" href="https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355979">uk.bl.ethos.355979</a>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20180919024900/https://www.era.lib.ed.ac.uk/handle/1842/11176">存档</a>于2018-09-19）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.aufirst=Robin+Campbell&rft.aulast=Allshire&rft.date=1985&rft.degree=PhD&rft.inst=University+of+Edinburgh&rft.title=Construction+and+analysis+of+vectors+based+on+bovine+papilloma+virus&rft_id=https%3A%2F%2Fwww.era.lib.ed.ac.uk%2Fhandle%2F1842%2F11176&rft_id=info%3Ahdl%2F1842%2F11176&rft_id=info%3Aoclcnum%2F606010479&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adissertation" class="Z3988"><span style="display:none;"> </span></span> <span style="position:relative; top: -2px;"><span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span> </li> <li id="cite_note-cv-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-cv_3-0"><sup><b>3.0</b></sup></a> <a href="#cite_ref-cv_3-1"><sup><b>3.1</b></sup></a></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://www.roche.de/presse/8-CV%20Southern.pdf">Edwin Southern CV</a> <span style="font-size:85%;">(PDF)</span>. Roche. <span class="reference-accessdate"> [<span class="nowrap">2019-01-16</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20120402052847/http://www.roche.de/presse/8-CV%20Southern.pdf">存档</a> <span style="font-size:85%;">(PDF)</span>于2012-04-02）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.btitle=Edwin+Southern+CV&rft.genre=unknown&rft.pub=Roche&rft_id=http%3A%2F%2Fwww.roche.de%2Fpresse%2F8-CV%2520Southern.pdf&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-nature_med_2005-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-nature_med_2005_4-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Southern, E. Tools for genomics. Nature Medicine. 2005, <b>11</b> (10): 1029–1034. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16211028"><span title="公共医学识别码">PMID 16211028</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnm1005-1029"><span title="數位物件識別號">doi:10.1038/nm1005-1029</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Tools+for+genomics&rft.aufirst=E.&rft.aulast=Southern&rft.date=2005&rft.genre=article&rft.issue=10&rft.jtitle=Nature+Medicine&rft.pages=1029-1034&rft.volume=11&rft_id=info%3Adoi%2F10.1038%2Fnm1005-1029&rft_id=info%3Apmid%2F16211028&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><cite class="citation journal">Southern, E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. Journal of Molecular Biology. 1975, <b>98</b> (3): 503–517. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1195397"><span title="公共医学识别码">PMID 1195397</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0022-2836%2875%2980083-0"><span title="數位物件識別號">doi:10.1016/S0022-2836(75)80083-0</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Detection+of+specific+sequences+among+DNA+fragments+separated+by+gel+electrophoresis&rft.aufirst=E.+M.&rft.aulast=Southern&rft.date=1975&rft.genre=article&rft.issue=3&rft.jtitle=Journal+of+Molecular+Biology&rft.pages=503-517&rft.volume=98&rft_id=info%3Adoi%2F10.1016%2FS0022-2836%2875%2980083-0&rft_id=info%3Apmid%2F1195397&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-#1-6"><span class="mw-cite-backlink">^ <a href="#cite_ref-#1_6-0"><sup><b>6.0</b></sup></a> <a href="#cite_ref-#1_6-1"><sup><b>6.1</b></sup></a></span> <span class="reference-text"><cite class="citation journal">Southern, E.; Mir, K.; Shchepinov, M. Molecular interactions on microarrays. Nature Genetics. 1999, <b>21</b> (1 Suppl): 5–9. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9915493"><span title="公共医学识别码">PMID 9915493</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F4429"><span title="數位物件識別號">doi:10.1038/4429</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Molecular+interactions+on+microarrays&rft.au=Mir%2C+K.&rft.au=Shchepinov%2C+M.&rft.aufirst=E.&rft.aulast=Southern&rft.date=1999&rft.genre=article&rft.issue=1+Suppl&rft.jtitle=Nature+Genetics&rft.pages=5-9&rft.volume=21&rft_id=info%3Adoi%2F10.1038%2F4429&rft_id=info%3Apmid%2F9915493&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><cite class="citation journal">Southern, E. Gel electrophoresis of restriction fragments. Methods in Enzymology. Methods in Enzymology. 1979, <b>68</b>: 152–176. <a href="/wiki/Special:%E7%BD%91%E7%BB%9C%E4%B9%A6%E6%BA%90/9780121819682" title="Special:网络书源/9780121819682"><span title="国际标准书号">ISBN</span> 9780121819682</a>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/232210"><span title="公共医学识别码">PMID 232210</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2F0076-6879%2879%2968011-4"><span title="數位物件識別號">doi:10.1016/0076-6879(79)68011-4</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Gel+electrophoresis+of+restriction+fragments&rft.aufirst=E.&rft.aulast=Southern&rft.date=1979&rft.genre=article&rft.isbn=9780121819682&rft.jtitle=Methods+in+Enzymology&rft.pages=152-176&rft.volume=68&rft_id=info%3Adoi%2F10.1016%2F0076-6879%2879%2968011-4&rft_id=info%3Apmid%2F232210&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><cite class="citation journal">Maskos, U.; Southern, E. M. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC312256">Oligonucleotide hybridisations on glass supports: A novel linker for oligonucleotide synthesis and hybridisation properties of oligonucleotides synthesised in situ</a>. Nucleic Acids Research. 1992, <b>20</b> (7): 1679–1684. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC312256"><span title="公共医学中心">PMC 312256</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1579459"><span title="公共医学识别码">PMID 1579459</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2F20.7.1679"><span title="數位物件識別號">doi:10.1093/nar/20.7.1679</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Oligonucleotide+hybridisations+on+glass+supports%3A+A+novel+linker+for+oligonucleotide+synthesis+and+hybridisation+properties+of+oligonucleotides+synthesised+in+situ&rft.au=Southern%2C+E.+M.&rft.aufirst=U.&rft.aulast=Maskos&rft.date=1992&rft.genre=article&rft.issue=7&rft.jtitle=Nucleic+Acids+Research&rft.pages=1679-1684&rft.volume=20&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC312256&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC312256&rft_id=info%3Adoi%2F10.1093%2Fnar%2F20.7.1679&rft_id=info%3Apmid%2F1579459&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span> <span style="position:relative; top: -2px;"><span typeof="mw:File"><a href="/wiki/%E5%BC%80%E6%94%BE%E8%8E%B7%E5%8F%96" title="开放获取文献，可免费阅读"><img alt="开放获取" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Open_Access_logo_PLoS_transparent.svg/9px-Open_Access_logo_PLoS_transparent.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Open_Access_logo_PLoS_transparent.svg/14px-Open_Access_logo_PLoS_transparent.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/77/Open_Access_logo_PLoS_transparent.svg/18px-Open_Access_logo_PLoS_transparent.svg.png 2x" data-file-width="640" data-file-height="1000" /></a></span></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><cite class="citation journal">Milner, N.; Mir, K. U.; Southern, E. M. Selecting effective antisense reagents on combinatorial oligonucleotide arrays. Nature Biotechnology. 1997, <b>15</b> (6): 537–541. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9181575"><span title="公共医学识别码">PMID 9181575</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnbt0697-537"><span title="數位物件識別號">doi:10.1038/nbt0697-537</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Selecting+effective+antisense+reagents+on+combinatorial+oligonucleotide+arrays&rft.au=Mir%2C+K.+U.&rft.au=Southern%2C+E.+M.&rft.aufirst=N.&rft.aulast=Milner&rft.date=1997&rft.genre=article&rft.issue=6&rft.jtitle=Nature+Biotechnology&rft.pages=537-541&rft.volume=15&rft_id=info%3Adoi%2F10.1038%2Fnbt0697-537&rft_id=info%3Apmid%2F9181575&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><cite class="citation journal">Southern, E. M. <a rel="nofollow" class="external text" href="https://search.proquest.com/docview/301213660">Studies on synthetic and naturally occurring enzyme metabolites.</a>. Scotland: University of Glasgow (United Kingdom). 1964 <span class="reference-accessdate"> [<span class="nowrap">2019-01-16</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20200407143559/https://search.proquest.com/docview/301213660">存档</a>于2020-04-07） <span style="font-family: sans-serif; cursor: default; color:var(--color-subtle, #54595d); font-size: 0.8em; bottom: 0.1em; font-weight: bold;" title="连接到英语网页">（英语）</span>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Studies+on+synthetic+and+naturally+occurring+enzyme+metabolites.&rft.aufirst=E.+M.&rft.aulast=Southern&rft.date=1964&rft.genre=article&rft_id=https%3A%2F%2Fsearch.proquest.com%2Fdocview%2F301213660&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-LancetBio-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-LancetBio_11-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Harding, A. Sir Edwin Southern: Scientist as problem solver. The Lancet. 2005, <b>366</b> (9501): 1919. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16325686"><span title="公共医学识别码">PMID 16325686</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0140-6736%2805%2967775-6"><span title="數位物件識別號">doi:10.1016/S0140-6736(05)67775-6</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Sir+Edwin+Southern%3A+Scientist+as+problem+solver&rft.aufirst=A.&rft.aulast=Harding&rft.date=2005&rft.genre=article&rft.issue=9501&rft.jtitle=The+Lancet&rft.pages=1919&rft.volume=366&rft_id=info%3Adoi%2F10.1016%2FS0140-6736%2805%2967775-6&rft_id=info%3Apmid%2F16325686&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://www.gairdner.org/winners.html">List of winners</a>. The Gairdner Foundation. <span class="reference-accessdate"> [<span class="nowrap">2007-12-19</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20071230095627/http://www.gairdner.org/winners.html">存档</a>于2007-12-30）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.btitle=List+of+winners&rft.genre=unknown&rft.pub=The+Gairdner+Foundation&rft_id=http%3A%2F%2Fwww.gairdner.org%2Fwinners.html&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-13">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://royalsociety.org/page.asp?id=1750">Royal recent winners</a>. <a href="/wiki/%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A" title="皇家学会">皇家学会</a>. <span class="reference-accessdate"> [<span class="nowrap">2007-12-20</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20071219185002/http://www.royalsociety.org/page.asp?id=1750">存档</a>于2007-12-19）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.btitle=Royal+recent+winners&rft.genre=unknown&rft.pub=%E7%9A%87%E5%AE%B6%E5%AD%A6%E4%BC%9A&rft_id=http%3A%2F%2Froyalsociety.org%2Fpage.asp%3Fid%3D1750&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-nature_med_20052-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-nature_med_20052_14-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Southern, E. Tools for genomics. Nature Medicine. 2005, <b>11</b> (10): 1029–1034. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16211028"><span title="公共医学识别码">PMID 16211028</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnm1005-1029"><span title="數位物件識別號">doi:10.1038/nm1005-1029</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.atitle=Tools+for+genomics&rft.aufirst=E.&rft.aulast=Southern&rft.date=2005&rft.genre=article&rft.issue=10&rft.jtitle=Nature+Medicine&rft.pages=1029-1034&rft.volume=11&rft_id=info%3Adoi%2F10.1038%2Fnm1005-1029&rft_id=info%3Apmid%2F16211028&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Lasker_acceptance_remarks-15"><span class="mw-cite-backlink"><b><a href="#cite_ref-Lasker_acceptance_remarks_15-0">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://www.laskerfoundation.org/awards/2005_c_accept_southern.htm">2005 Albert Lasker Award – Acceptance remarks by Edwin Southern</a>. Lasker Foundation. <span class="reference-accessdate"> [<span class="nowrap">2019-01-16</span>]</span>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20080610105040/http://www.laskerfoundation.org/awards/2005_c_accept_southern.htm">存档</a>于2008-06-10）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.btitle=2005+Albert+Lasker+Award+%E2%80%93+Acceptance+remarks+by+Edwin+Southern&rft.genre=unknown&rft.pub=Lasker+Foundation&rft_id=http%3A%2F%2Fwww.laskerfoundation.org%2Fawards%2F2005_c_accept_southern.htm&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Lasker_2005-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-Lasker_2005_16-0">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20071211191805/http://www.laskerfoundation.org/awards/library/2005clinical.shtml">2005 Albert Lasker Award for Clinical Medical Research</a>. Lasker Foundation. <span class="reference-accessdate"> [<span class="nowrap">2007-12-19</span>]</span>. （<a rel="nofollow" class="external text" href="http://www.laskerfoundation.org/awards/library/2005clinical.shtml">原始内容</a>存档于2007-12-11）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E5%9F%83%E5%BE%B7%E6%B8%A9%C2%B7%E8%90%A8%E7%91%9F%E6%81%A9&rft.btitle=2005+Albert+Lasker+Award+for+Clinical+Medical+Research&rft.genre=unknown&rft.pub=Lasker+Foundation&rft_id=http%3A%2F%2Fwww.laskerfoundation.org%2Fawards%2Flibrary%2F2005clinical.shtml&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r84265675">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist 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