Autoimmune Diseases | Rheumatology

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Researchers have identified more than 100 rheumatic disorders and suspect at least 40 additional diseases of having an autoimmune background. These diseases are chronic and can be life-threatening. A rheumatic disorder may affect one or more organs including joints, bones, muscles, the skin and connective tissue, and blood vessels.</p> <p>With improvements in understanding of the immune system and molecules that mediate inflammation, new therapies continue to be developed for multiple autoimmune indications. Studies often share similar clinical and operational considerations, challenges and risks. It is important to work with a research partner that has experience across multiple therapy areas.</p> <p>ICON leverages its expertise to advance and help companies develop innovative medicines for people living with rheumatic autoimmune diseases. We provide strategic direction and end-to-end services to support all phases of autoimmune therapies development. As a full service contract research organisation, we have the experience and the in-depth knowledge to handle all aspects of product development. Our expert teams anticipate the challenges and offer proven mitigation strategies to ensure patient safety as well as efficient study operation and execution. This ICON team of core professionals includes four board certified rheumatologists and is organised within the Rheumatology Center of Excellence (CoE), supporting programs with applied knowledge and past projects experience.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="5e44ce8b-e939-44e2-8c1a-c7168b4a5a73" class="icon-group icon-group--horizontal"> <div class="container-fluid container-fluid--xl"> <h2 class="icon-group__title">ICON Rheumatology experience in the last ten years</h2> <ul class="icon-group__items icon-group__items__columns-3"> <li class="icon-group__item--blue"> <div lang="en" class="icon-group__wrapper" > <i class="icon-notes"></i> <p class="mb-2 icons-large-text">93</p> <small>Studies conducted</small> </div> </li> <li class="icon-group__item--green-bright"> <div lang="en" class="icon-group__wrapper" > <i class="icon-team"></i> <p class="mb-2 icons-large-text">25,456</p> <small>Patients involved</small> </div> </li> <li class="icon-group__item--blue-light"> <div lang="en" class="icon-group__wrapper" > <i class="icon-global"></i> <p class="mb-2 icons-large-text">5,346</p> <small>Sites worldwide</small> </div> </li> </ul> </div> </div> <div id="4731e2eb-1e1f-4107-b219-afad6378a2e4"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> </h3> <div> <p>ICON holds global clinical trial experience in a variety of <a href="/therapeutics/internal-medicine-and-immunology/" target="_self">immunology areas</a>, including:</p> <table border="0" cellpadding="1" cellspacing="1" style="width: 500px;"> <tbody> <tr> <td style="vertical-align: top; width: 50%;"> <ul> <li>Rheumatoid Arthritis</li> <li>Psoriatic Arthritis</li> <li>Ankylosing Spondylitis</li> <li>Systemic Lupus Erythematosus (SLE)</li> </ul> </td> <td style="vertical-align: top;"> <ul> <li>Fibromyalgia</li> <li>Myositis</li> <li>Juvenile Rheumatoid Arthritis</li> <li>Sjögren's Syndrome</li> <li>Uveitis</li> </ul> </td> </tr> </tbody> </table> </div> </div> </div> </div> </div> </div> </div> </div> </div><div id="2c54a176-9b78-45a4-be92-67054d66d09b"> <div> <div class="file file--with-thumbnail"> <div class="container-fluid container-fluid--xl"> <a href="https://www2.iconplc.com/factsheet/autoimmune" target="_blank" title="Factsheet: Autoimmune Diseases - Rheumatology"> <span class="file__thumbnail"> <div> <div><div><img src="https://icon.widen.net/content/cd071238-42b8-4420-b65c-9bcd5d289197/web/rheumatology.jpg?h=240&itok=vKoALkVv" width="170" height="240" alt="rheumatology.jpg" loading="lazy" title="rheumatology.jpg" /> </div> </div> </div> </span> <span class="file__details"> <h3>Factsheet: Autoimmune Diseases - Rheumatology</h3> <p>Learn more in our factsheet. Download your copy today.</p> </span> </a> </div> </div> </div> </div> <div id="b365f26d-ec9b-4720-8999-c22548f16430" class="icon-group icon-group--horizontal"> <div class="container-fluid container-fluid--xl"> <h2 class="icon-group__title">Accellacare experience in rheumatology clinical studies</h2> <ul class="icon-group__items icon-group__items__columns-3"> <li class="icon-group__item--blue"> <div lang="en" class="icon-group__wrapper" > <i class="icon-content-development"></i> <p class="mb-2 icons-large-text">276</p> <small>Pain studies conducted</small> </div> </li> <li class="icon-group__item--green-bright"> <div lang="en" class="icon-group__wrapper" > <i class="icon-patient"></i> <p class="mb-2 icons-large-text">7,340</p> <small>Patients involved</small> </div> </li> <li class="icon-group__item--blue-light"> <div lang="en" class="icon-group__wrapper" > <i class="icon-global"></i> <p class="mb-2 icons-large-text">153</p> <small>Sites worldwide</small> </div> </li> </ul> </div> </div> <div id="589f20d8-6797-4848-83d4-6bd12e7b5625"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> </h3> <div><p><a href="http://www.accellacare.com" target="_blank">Accellacare</a>, ICON's dedicated global site network, has strong experience in osteoarthritis, osteoporosis, and rheumatoid arthritis and provides a range of services for both ICON and sponsor-direct studies:</p><table style="width:750px;" align="left" border="0" cellpadding="1" cellspacing="1"><tbody><tr><td style="width:50%;"><ul><li>Board Certified Internal Medicine, Rheumatologists Family Physicians,and Orthopaedic Surgeons</li><li>VAS Questionnaire</li><li>Womac Questionnaire</li><li>Access to Xray/MRI</li><li>Joint Count Experience</li><li>T.B Quantiferon test</li><li>ESR</li></ul></td><td><ul><li>Availability of Dexa Machines</li><li>Electronic diary management/training</li><li>Chest x ray interpretation</li><li>End point collection</li><li>Current knowledge regarding use of Anti-Rheumatics and Analgesics</li><li>Experience in Monoclonal and biosimilars</li><li>Experience in <a href="https://www.iconplc.com/solutions/consulting/commercial-positioning-consulting/patient-reported-outcomes/">Patient Reported Outcomes</a></li><li>Experience in local injections</li></ul></td></tr></tbody></table><p> </p></div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="1db40552-4778-405b-b49f-ba3bee27657b"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-3"> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-9"> <div class="text-picture__text"> <h2></h2> <h3>Integrated services</h3> <div><p>Our integrated services include:</p><ul><li><a href="https://www.iconplc.com/solutions/early-phase/">Early Phase Research</a>: Staff dedicated exclusively to conducting early phase research, from First-in-Human (FIH) through Proof of Concept (POC)</li><li><a href="https://www.iconplc.com/solutions/site-and-patient-solutions/global-recruitment-solutions/">Site Selection and Engagement</a>: Close relationships with thousands of investigators and Key Opinion Leaders (KOLs), Electronic Medical Records on 100 million patients, and technology solutions for training and engaging sites</li><li>Expedited Study Start Up: Smart processes and specialized teams to support your race to market</li><li><a href="https://www.iconplc.com/solutions/consulting/asset-development/adaptive-trials/index.xml">Adaptive Study Design</a><a href="/services/adaptive-trials/" target="_self">:</a> Adaptive trial designs through combining comprehensive tools with state-of-the-art methodology</li><li><a href="https://www.iconplc.com/solutions/consulting/commercial-positioning-consulting/market-access/index.xml">Patient Recruitment and Engagement</a>: A focused approach that includes patient-centric services, site support services, and an online learning management system - <a href="https://www.iconplc.com/solutions/technologies/firecrest/">FIRECREST</a></li><li>An expert <a href="https://www.iconplc.com/solutions/consulting/commercial-positioning-consulting/market-access/index.xml">Clinical Outcomes Assessments </a>group with experience in dermatology and rheumatology PRO and Clinical assessment instruments creation and validation</li><li><a href="https://www.iconplc.com/solutions/imaging/">Medical Imaging</a>: Over 200 imaging specialists providing photo services, centralized assessment and adjudication of study endpoints</li><li>Independent <a href="https://www.iconplc.com/news-events/events/webinars/fda-guidance-use-data-monitoring-committees-clinical-trials">DMC Management</a> and <a href="https://www.iconplc.com/solutions/clinical-and-scientific-operations/endpoint-adjudication-services/">Endpoint Adjudication</a> IDEA with experience in Inflammation and Autoimmunity endpoints</li><li><a href="https://www.iconplc.com/solutions/laboratories/">Laboratory Services</a>: A global network of wholly-owned laboratories that can receive samples within 48 hours</li><li><a href="https://www.iconplc.com/solutions/clinical-and-scientific-operations/biostatistics/">Biostatistical Analysis</a>: A dedicated team to help in developing your protocol and perform PK modeling calculations</li><li><a href="https://www.iconplc.com/solutions/consulting/commercial-positioning-consulting/market-access/index.xml">Commercialisation and Outcomes</a>: Professional services to establish and communicate your product’s unique clinical and economic value</li><li>Data Analytics: <a href="https://www.iconplc.com/solutions/technologies/ICONIK/">ICONIK </a>decision-support platform provides a single view of study data to manage data quality, support a risk-based approach via analysis and visualization of trends, ensure compliance with assessment schedules, assess site performance, analyse and manage quality of rating scales and scoring tools</li></ul></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </second> </div> <div class="col-md-3 order-1"> <div id="2f7366c3-d0e3-4003-8042-315d90131cb4"> <div class="container-fluid container-fluid--xl sidebar-menu-wrapper"> <div class="sidebar"> <div class="sidebar sidebar--sticky sidebar--collapsible"> <a class="sidebar--collapsible__toggle collapsed" role="button" data-toggle="collapse" href="#sidebar-content" aria-expanded="false" aria-controls="sidebar-content"> <span>In this section</span> </a> <div class="sidebar--collapsible__content collapse" id="sidebar-content"> <div class="sidebar--menu"> <h6 class="d-none d-md-block">In this section</h6> <ul class="sidebar--collapsible__list"> <li> <a href="/therapeutics/biosimilars" data-drupal-link-system-path="node/33807">Biosimilars</a> <div class="collapse " id="biosimilars-10484" > </div> </li> <li> <a href="/therapeutics/cardiovascular" title="ICON has extensive experience in cardiovascular clinical research trials across the entire drug development spectrum." data-drupal-link-system-path="node/34066">Cardiovascular</a> <div class="collapse " id="cardiovascular-10511" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#cell-and-gene-therapies-10512"></span> <a href="/therapeutics/cell-and-gene-therapies" data-drupal-link-system-path="node/34067">Cell and Gene Therapies</a> <div class="collapse " id="cell-and-gene-therapies-10512" > <ul class="menu menu-level-1"> <li> <a href="/insights/value-based-healthcare/the-affordability-hurdle-for-gene-therapies" data-drupal-link-system-path="node/33755">The affordability hurdle for gene therapies</a> <div class="collapse " id="cell-and-gene-therapies-the-affordability-hurdle-for-gene-therapies-10513" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#central-nervous-system-10514"></span> <a href="/therapeutics/central-nervous-system" data-drupal-link-system-path="node/34071">Central Nervous System</a> <div class="collapse " id="central-nervous-system-10514" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/central-nervous-system/cns-neurology" data-drupal-link-system-path="node/34068">CNS Neurology</a> <div class="collapse " id="central-nervous-system-cns-neurology-10515" > </div> </li> <li> <a href="/therapeutics/central-nervous-system/cns-pain" data-drupal-link-system-path="node/34069">CNS Pain</a> <div class="collapse " id="central-nervous-system--cns-pain-10516" > </div> </li> <li> <a href="/therapeutics/central-nervous-system/cns-psychiatry" data-drupal-link-system-path="node/34070">CNS Psychiatry</a> <div class="collapse " id="central-nervous-system---cns-psychiatry-10517" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/challenges-and-opportunities-in-traumatic-brain-injury-clinical-trials" data-drupal-link-system-path="node/33678">Challenges and opportunities in traumatic brain injury clinical trials</a> <div class="collapse " id="central-nervous-system----challenges-and-opportunities-in-traumatic-brain-injury-clinical-trials-10518" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/key-considerations-for-parkinsons-disease-trials" data-drupal-link-system-path="node/33680">Challenges and opportunities in Parkinson’s Disease clinical trials</a> <div class="collapse " id="central-nervous-system-----challenges-and-opportunities-in-parkinson-s-disease-clinical-trials-10519" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/key-considerations-in-chronic-pain-clinical-trials" data-drupal-link-system-path="node/33681">Key considerations in chronic pain clinical trials</a> <div class="collapse " id="central-nervous-system------key-considerations-in-chronic-pain-clinical-trials-10520" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#endocrine-metabolic-disorders-10521"></span> <a href="/therapeutics/endocrine-metabolic-disorders" data-drupal-link-system-path="node/34072">Endocrine & Metabolic Disorders</a> <div class="collapse " id="endocrine-metabolic-disorders-10521" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/endocrine-metabolic-disorders/obesity" data-drupal-link-system-path="node/38991">Obesity</a> <div class="collapse " id="endocrine-metabolic-disorders-obesity-11021" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#endocrine-metabolic-disorders--metabolic-dysfunction-associated-steatohepatitis-mash--10522"></span> <a href="/therapeutics/endocrine-metabolic-disorders/non-alcoholic-steatohepatitis-nash" data-drupal-link-system-path="node/34073">Metabolic dysfunction-associated steatohepatitis (MASH)</a> <div class="collapse " id="endocrine-metabolic-disorders--metabolic-dysfunction-associated-steatohepatitis-mash--10522" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/nash/the-voice-of-nash-investigators-in-patient-recruitment" data-drupal-link-system-path="node/33694">The voice of NASH investigators</a> <div class="collapse " id="metabolic-dysfunction-associated-steatohepatitis-mash--the-voice-of-nash-investigators-10523" > </div> </li> </ul> </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#infectious-diseases-10524"></span> <a href="/therapeutics/infectious-diseases" data-drupal-link-system-path="node/34076">Infectious Diseases</a> <div class="collapse " id="infectious-diseases-10524" > <ul class="menu menu-level-1"> <li> <a href="/insights/therapeutics/infectious-diseases/antimicrobial-resistance" data-drupal-link-system-path="node/33685">Antimicrobial resistance</a> <div class="collapse " id="infectious-diseases-antimicrobial-resistance-10525" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/hiv" data-drupal-link-system-path="node/33689">HIV</a> <div class="collapse " id="infectious-diseases--hiv-10526" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccine-trials" data-drupal-link-system-path="node/33687">Pandemic respiratory vaccine clinical trials</a> <div class="collapse " id="infectious-diseases---pandemic-respiratory-vaccine-clinical-trials-10527" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class=" " data-toggle="collapse" role="button" href="#internal-medicine-immunology-10528"></span> <a href="/therapeutics/internal-medicine-immunology" data-drupal-link-system-path="node/34080">Internal Medicine & Immunology</a> <div class="collapse show" id="internal-medicine-immunology-10528" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/internal-medicine-and-immunology/dermatology" data-drupal-link-system-path="node/34077">Dermatology</a> <div class="collapse " id="internal-medicine-immunology-dermatology-10529" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#internal-medicine-immunology--gastrointestinal-10530"></span> <a href="/therapeutics/internal-medicine-immunology/gastrointestinal" data-drupal-link-system-path="node/34078">Gastrointestinal</a> <div class="collapse " id="internal-medicine-immunology--gastrointestinal-10530" > <ul class="menu menu-level-2"> <li> <a href="/therapeutics/internal-medicine-and-immunology/gastrointestinal/inflammatory-bowel-disease" data-drupal-link-system-path="node/34079">Inflammatory Bowel Disease</a> <div class="collapse " id="gastrointestinal-inflammatory-bowel-disease-10531" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/ophthalmology" data-drupal-link-system-path="node/34081">Ophthalmology</a> <div class="collapse " id="internal-medicine-immunology---ophthalmology-10532" > </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/respiratory" data-drupal-link-system-path="node/34082">Respiratory</a> <div class="collapse " id="internal-medicine-immunology----respiratory-10533" > </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/rheumatology" class="active is-active" data-drupal-link-system-path="node/34083">Rheumatology</a> <div class="collapse show" id="internal-medicine-immunology-----rheumatology-10534" > </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/transplant-immunology" data-drupal-link-system-path="node/34091">Transplant Immunology</a> <div class="collapse " id="internal-medicine-immunology------transplant-immunology-10544" > </div> </li> <li> <a href="/therapeutics/internal-medicine-and-immunology/urology" data-drupal-link-system-path="node/34084">Urology</a> <div class="collapse " id="internal-medicine-immunology-------urology-10535" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/medical-device" data-drupal-link-system-path="node/34085">Medical Device</a> <div class="collapse " id="medical-device-10536" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#oncology-10537"></span> <a href="/therapeutics/oncology" data-drupal-link-system-path="node/34088">Oncology</a> <div class="collapse " id="oncology-10537" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/oncology/early-phase-oncology" data-drupal-link-system-path="node/34086">Early Phase Oncology</a> <div class="collapse " id="oncology-early-phase-oncology-10538" > </div> </li> <li> <a href="/therapeutics/oncology/immuno-oncology" data-drupal-link-system-path="node/34087">Immuno-Oncology</a> <div class="collapse " id="oncology--immuno-oncology-10539" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/pediatrics" data-drupal-link-system-path="node/34089">Pediatrics</a> <div class="collapse " id="pediatrics-10540" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#rare-orphan-diseases-10541"></span> <a href="/therapeutics/rare-orphan-diseases" data-drupal-link-system-path="node/34090">Rare & Orphan Diseases</a> <div class="collapse " id="rare-orphan-diseases-10541" > <ul class="menu menu-level-1"> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/leveraging-historical-data-for-use-in-rare-disease-trials" data-drupal-link-system-path="node/33707">Leveraging historical data for use in rare disease trials</a> <div class="collapse " id="rare-orphan-diseases-leveraging-historical-data-for-use-in-rare-disease-trials-10542" > </div> </li> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/patient-centricity-in-orphan-drug-development" data-drupal-link-system-path="node/33709">Patient centricity in orphan drug development</a> <div class="collapse " id="rare-orphan-diseases--patient-centricity-in-orphan-drug-development-10543" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#vaccines-10546"></span> <a href="/therapeutics/vaccines" data-drupal-link-system-path="node/34092">Vaccines</a> <div class="collapse " id="vaccines-10546" > <ul class="menu menu-level-1"> <li> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccine-trials" data-drupal-link-system-path="node/33687">Pandemic respiratory vaccine clinical trials</a> <div class="collapse " id="vaccines-pandemic-respiratory-vaccine-clinical-trials-10547" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/womens-health" data-drupal-link-system-path="node/34094">Women's Health</a> <div class="collapse " id="women-s-health-10545" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights-10548"></span> <a href="/insights/therapeutics" data-drupal-link-system-path="node/33684">Therapeutics insights</a> <div class="collapse " id="therapeutics-insights-10548" > <ul class="menu menu-level-1"> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights-cardiovascular-10549"></span> <a href="/insights/therapeutics/cardiovascular" data-drupal-link-system-path="node/33670">Cardiovascular</a> <div class="collapse " id="therapeutics-insights-cardiovascular-10549" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/cardiovascular/mitigating-the-impact-of-covid19-on-cardiovascular-trials" data-drupal-link-system-path="node/33671">Mitigating the impact of COVID-19 on cardiovascular trials</a> <div class="collapse " id="cardiovascular-mitigating-the-impact-of-covid-19-on-cardiovascular-trials-10550" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights--cell-and-gene-therapies-10551"></span> <a href="/insights/therapeutics/cell-and-gene-therapies" data-drupal-link-system-path="node/33674">Cell and Gene Therapies</a> <div class="collapse " id="therapeutics-insights--cell-and-gene-therapies-10551" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/cell-and-gene-therapies/approaching-the-car-t-cell-therapy-horizon" data-drupal-link-system-path="node/33672">Approaching the CAR T-cell therapy horizon</a> <div class="collapse " id="cell-and-gene-therapies-approaching-the-car-t-cell-therapy-horizon-10552" > </div> </li> <li> <a href="/insights/therapeutics/cell-and-gene-therapies/cell-and-gene-therapy-clinical-trials" data-drupal-link-system-path="node/33673">Cell and Gene ebook</a> <div class="collapse " id="cell-and-gene-therapies--cell-and-gene-ebook-10553" > </div> </li> <li> <a href="/insights/therapeutics/cell-and-gene-therapies/long-term-follow-up-studies-of-cell-and-gene-therapies" data-drupal-link-system-path="node/33675">Long-term follow-up studies of cell and gene therapies</a> <div class="collapse " id="cell-and-gene-therapies---long-term-follow-up-studies-of-cell-and-gene-therapies-10554" > </div> </li> <li> <a href="/insights/therapeutics/cell-and-gene-therapies/mainstreaming-cell-gene-therapies" data-drupal-link-system-path="node/33676">Mainstreaming Cell & Gene Therapies</a> <div class="collapse " id="cell-and-gene-therapies----mainstreaming-cell-gene-therapies-10555" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights---central-nervous-system-10556"></span> <a href="/insights/therapeutics/central-nervous-system" data-drupal-link-system-path="node/33679">Central Nervous System</a> <div class="collapse " id="therapeutics-insights---central-nervous-system-10556" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/central-nervous-system/a-mind-for-digital-therapeutics" data-drupal-link-system-path="node/33677">A mind for digital therapeutics</a> <div class="collapse " id="central-nervous-system-a-mind-for-digital-therapeutics-10557" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/challenges-and-opportunities-in-traumatic-brain-injury-clinical-trials" data-drupal-link-system-path="node/33678">Challenges and opportunities in traumatic brain injury clinical trials</a> <div class="collapse " id="central-nervous-system--challenges-and-opportunities-in-traumatic-brain-injury-clinical-trials-10558" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/key-considerations-for-parkinsons-disease-trials" data-drupal-link-system-path="node/33680">Challenges and opportunities in Parkinson’s Disease clinical trials</a> <div class="collapse " id="central-nervous-system---challenges-and-opportunities-in-parkinson-s-disease-clinical-trials-10559" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/key-considerations-in-chronic-pain-clinical-trials" data-drupal-link-system-path="node/33681">Key Considerations in Chronic Pain Clinical Trials</a> <div class="collapse " id="central-nervous-system----key-considerations-in-chronic-pain-clinical-trials-10560" > </div> </li> </ul> </div> </li> <li> <a href="/insights/therapeutics/glycomics" data-drupal-link-system-path="node/33683">Glycomics</a> <div class="collapse " id="therapeutics-insights----glycomics-10562" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights-----infectious-diseases-10563"></span> <a href="/insights/therapeutics/infectious-diseases" data-drupal-link-system-path="node/33690">Infectious Diseases</a> <div class="collapse " id="therapeutics-insights-----infectious-diseases-10563" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/infectious-diseases/antimicrobial-resistance" data-drupal-link-system-path="node/33685">Antimicrobial Resistance</a> <div class="collapse " id="infectious-diseases-antimicrobial-resistance-10564" > </div> </li> <li> <a href="/therapeutics/therapeutics-insights/infectious-diseases/considerations-strengthening-vaccine" data-drupal-link-system-path="node/33686">Considerations for strengthening vaccine development</a> <div class="collapse " id="infectious-diseases--considerations-for-strengthening-vaccine-development-10565" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccine-trials" data-drupal-link-system-path="node/33687">COVID-19 vaccine trials</a> <div class="collapse " id="infectious-diseases---covid-19-vaccine-trials-10566" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccines-pass" data-drupal-link-system-path="node/33688">COVID-19 vaccines: Post-authorisation safety surveillance</a> <div class="collapse " id="infectious-diseases----covid-19-vaccines-post-authorisation-safety-surveillance-10567" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/hiv" data-drupal-link-system-path="node/33689">HIV</a> <div class="collapse " id="infectious-diseases-----hiv-10568" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/the-value-of-dynamic-transmission-models" data-drupal-link-system-path="node/33691">The value of dynamic transmission models</a> <div class="collapse " id="infectious-diseases------the-value-of-dynamic-transmission-models-10569" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights------nash-10571"></span> <a href="/insights/therapeutics/nash" data-drupal-link-system-path="node/33693">NASH</a> <div class="collapse " id="therapeutics-insights------nash-10571" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/nash/the-voice-of-nash-investigators-in-patient-recruitment" data-drupal-link-system-path="node/33694">The voice of NASH investigators</a> <div class="collapse " id="nash-the-voice-of-nash-investigators-10572" > </div> </li> </ul> </div> </li> <li> <a href="/insights/therapeutics/womens-health-insights" data-drupal-link-system-path="node/39166">Women's Health Insights</a> <div class="collapse " id="therapeutics-insights-------women-s-health-insights-11176" > </div> </li> <li> <a href="/insights/therapeutics/oncology" data-drupal-link-system-path="node/33698">Oncology</a> <div class="collapse " id="therapeutics-insights--------oncology-10576" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights---------pediatrics-10577"></span> <a href="/insights/therapeutics/pediatrics" data-drupal-link-system-path="node/33699">Pediatrics</a> <div class="collapse " id="therapeutics-insights---------pediatrics-10577" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/pediatrics/pediatric-risk-assessment-map" data-drupal-link-system-path="node/33700">Pediatric Risk Assessment Map</a> <div class="collapse " id="pediatrics-pediatric-risk-assessment-map-10578" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#therapeutics-insights----------rare-and-orphan-diseases-10579"></span> <a href="/insights/therapeutics/rare-and-orphan-diseases" data-drupal-link-system-path="node/33706">Rare and orphan diseases</a> <div class="collapse " id="therapeutics-insights----------rare-and-orphan-diseases-10579" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/pushing-boundaries-idiopathic-pulmonary" data-drupal-link-system-path="node/34969">Pushing boundaries in idiopathic pulmonary fibrosis clinical research</a> <div class="collapse " id="rare-and-orphan-diseases-pushing-boundaries-in-idiopathic-pulmonary-fibrosis-clinical-research-10861" > </div> </li> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/advanced-therapies-for-rare-diseases" data-drupal-link-system-path="node/33701">Advanced therapies for rare diseases</a> <div class="collapse " id="rare-and-orphan-diseases--advanced-therapies-for-rare-diseases-10580" > </div> </li> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/cross-border-enrollment-of-rare-disease-patients" data-drupal-link-system-path="node/33702">Cross-border enrollment of rare disease patients</a> <div class="collapse " id="rare-and-orphan-diseases---cross-border-enrollment-of-rare-disease-patients-10581" > </div> 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