>New, Multilayer Material for Syringes & Vials, OXYCAPT™ | Business & Products

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OXYCAPT™<br class="sp-dsp-block">multilayer plastic vials</h1> <p class="catch">MGC’s new multilayer advanced material, <br class="sp-dsp-none">OXYCAPT™, integrates the best of plastic and <br class="sp-dsp-none">glass for plastic vials</p> <figure class="sp-dsp-block sp-gb-pagetitle"><img src="/eng/products/abd/img/oxycapt_bg_pagetitle_sp.jpg" alt=""></figure> </div> </section> <section> <ul class="link-ac noBg textItalic"> <li><a href="#ac01">What is OXYCAPT™?</a></li> <li><a href="#ac02">Why it’s better</a></li> <li><a href="#ac03">OXYCAPT™ in use</a></li> <li><a href="#ac04">OXYCAPT™ advantages</a></li> </ul> </section> <section> <h2 id="ac01" class="ttl-h2 alignC sp-alignL"><span class="sub">What is OXYCAPT™? </span>New plastic vial with both properties of glass and plastic</h2> <div class="boxContentsS"> <p>Traditional glass and plastic materials for syringes and vials are filled with problems. Glass suffers from a range of issues—such as high-breakability and poor PH stability—while plastic has an insufficient oxygen barrier and UV barrier. The US FDA and pharmaceutical companies have searched for solutions. Competitors have launched advanced material products, but their imperfect oxygen barriers and drug stability have been met with criticism.</p> <p>This led to the creation of OXYCAPT™—MGC’s new, lightweight, multilayer material, with all the benefits of glass and plastic.</p> <p>MGC’s OXYCAPT™ unites the best qualities of glass and plastic in a three-tiered, multilayer, advanced material that features an excellent water vapor barrier & drug contact layer made from COP (Cyclo Olefin Polymer) and an oxygen barrier layer with an oxygen barrier polymer. With low extractables, low protein absorption, and low breakability, all components come together to produce the best high oxygen barrier material on the market.</p> <h3 class="ttl-fig pT30">Multilayer Configuration</h3> <figure><img src="/eng/products/abd/img/oxycapt_p01.jpg" alt="Photo and figure: Regarding OXYCAPT" width="476" height=""></figure> </div> </section> <section> <h2 id="ac02" class="ttl-h2 alignC sp-alignL"><span class="sub">Why it’s better</span>A breakthrough in longer-lasting, safer medications</h2> <div class="boxContentsS"> <p>OXYCAPT™ provides high oxygen & CO<sub>2</sub> barrier —along with the low inorganic extractables, low breakability, and lightweight properties of plastic. Inorganic low molecular extractables are below that of Type I glass. Excellent UV absorption means drugs last longer, with improved stability and efficacy throughout their lifespan.</p> <p>Also for biologics and biosimilars, OXYCAPT™’s low extractables, high-breakage resistance, and high oxygen barrier—plus an improved UV barrier that absorbs UV and preserves drugs longer—make it the best, advanced material. Pharmaceutical companies with gene/cell therapy products also see benefits.</p> <div class="sp-table-scroll mT30"> <table class="table-data w100-Per"> <thead class="alignC"> <tr> <th scope="col"> </th> <th class="w20" scope="col">Glass</th> <th class="w20" scope="col">COP <br>(Cyclo Olefin Polymer)</th> <th class="w20" scope="col">OXYCAPT™-P</th> </tr> </thead> <tbody class="alignC"> <tr> <th class="w20" scope="row">Oxygen & CO<sub>2</sub> Barrier</th> <td>Excellent</td> <td>Not Good</td> <td>Good</td> </tr> <tr> <th scope="row">Water Vapor Barrier</th> <td>Excellent</td> <td>Good</td> <td>Good</td> </tr> <tr> <th scope="row">Resistance to Breakage<br>(Normal Temp.) </th> <td>Bad</td> <td>Good</td> <td>Good</td> </tr> <tr> <th scope="row">Resistance to Breakage <br>(Deep Cold Temp.) </th> <td>Bad</td> <td>Not Good</td> <td>Good</td> </tr> <tr> <th scope="row">Conteiner Closure Integrity (Deep Cold Temp.)</th> <td>Bad</td> <td>Not Good</td> <td>Good</td> </tr> <tr> <th scope="row">Inorganic Extractables</th> <td>Not Good</td> <td>Excellent</td> <td class="bg01">Excellent</td> </tr> <tr> <th scope="row">Organic Extractables</th> <td>Excellent</td> <td>Excellent</td> <td class="bg01">Excellent</td> </tr> <tr> <th scope="row">Protein Adsorption</th> <td>Not Good</td> <td>Good</td> <td>Good</td> </tr> <tr> <th scope="row">pH Stability</th> <td>Not Good</td> <td>Good</td> <td>Good</td> </tr> <tr> <th scope="row">UV Barrier</th> <td>Bad</td> <td>Bad</td> <td>Good</td> </tr> <tr> <th scope="row">Weight</th> <td>Bad</td> <td>Excellent</td> <td class="bg01">Excellent</td> </tr> <tr> <th scope="row">Disposability</th> <td>Bad</td> <td>Good</td> <td>Good</td> </tr> <tr> <th scope="row">Heat Resistance</th> <td>Excellent</td> <td>Good</td> <td>Not Good</td> </tr> </tbody> </table> </div> <p class="textS alignR">* Excellent − Good − Not Good − Bad</p> </div> </section> <section> <h2 id="ac03" class="ttl-h2 alignC sp-alignL"><span class="sub">OXYCAPT™ in use</span>The best choice for biologics and cell/gene therapy products</h2> <div class="boxContentsS"> <div class="box-clm2 clearfix mT1L"> <p class="boxL">MGC’s OXYCAPT™ plastic vials are the right solution for parenteral pharmaceutical liquid medication storage. OXYCAPT™’s multilayer construction preserves drug stability and shelf life in plastic vials, with significantly reduced oxidation, compared to COP. Long-term trials find OXYCAPT™ eliminates the problem of delamination (visible small flakes and particles from glass deterioration over time) in glass, while maintaining its oxygen barrier. OXYCAPT™ also resolves poor stability and low visibility issues found in plastics.  In addition, OXYCAPT™'s CO2 barrier and resistance to deep-cold storage have been appreciated by pharmaceutical companies because next generation drugs stored at cryogenic temperature and transported with dry ices have become popular recently.</p> <div class="boxR"> <figure><img src="/eng/products/abd/img/oxycapt_p04.jpg" alt="Photo: OXYCAPT vials" width="347" height=""></figure> </div> </div> </div> </section> <section> <h2 id="ac04" class="ttl-h2 alignC sp-alignL"><span class="sub">The OXYCAPT™ Advantage</span>Outperforming plastic with superior material</h2> <div class="boxContentsS"> <h3 class="ttl-h3 alignC mT0">Oxygen & CO<sub>2</sub> Barrier</h3> <p>OXYCAPT™-P Vial has high oxygen & CO<sub>2</sub> barrier property. The oxygen & CO<sub>2</sub> barrier is about 20 times better than COP. The result ensures consumers, pharmaceutical companies, biopharmaceutical companies, and entrepreneurial ventures looking to deliver biosimilars, biomedicines of advanced biologics, and cell/gene therapy products, receive effective medication after longer periods of storage time.</p> <h4 class="ttl-fig pT30">10ml Vial</h4> <figure><img src="/eng/products/abd/img/oxycapt_p06e.png" alt="Graph and photo: Gas barriers of OXYCAPT" width="735" height="363"></figure> <div class="mT20"> <ul class="list-dot"> <li>Measurement Device : MOCON OX-TRAN<sup>®</sup> 2/61</li> <li>Condition : 23℃ / In 100%RH, Out 50%RH</li> </ul> <p>　　<img src="/eng/products/files/oxycapt_p07e.png" width="735" height="363" alt="Graph and photo: CO2 Gas barriers of OXYCAPT"></p> <ul class="list-dot"> <li>Measurement Device : Lighthouse Instruments FMS-CO2*</li> <li>Storage Condition：23℃ / 0%RH</li> <li>Measurement Condition : 23℃ / 50%RH<br>  *CO2 partial pressure measured by FMS-CO2 was converted into CO2 permeability.</li> </ul> </div> <h3 class="ttl-h3 alignC">UV Barrier</h3> <p>Pharmaceutical companies heavily focus on improving UV barriers of packaging container materials because UV deteriorates drug contents and stability. Through UV absorption, OXYCAPT™ protects drugs better than COP and Glass Type I by cutting off UV light below 300 nm.</p> <figure class="mT30"><img src="/eng/products/abd/img/oxycapt_p08_pc.png" alt="Graph and photo: UV barriers of OXYCAPT" width="725" height="363"></figure> <h3 class="ttl-h3 alignC">Inorganic Extractables</h3> <p>Increased scrutiny by regulators has led the medical, pharmaceutical and biopharmaceutical industry to focus on inorganic extractable assessments to ensure patient safety and drug interaction. OXYCAPT™ outperforms all plastic and glass advanced materials—including Type 1 Glass, COP, PP, and PE—currently on the market.</p> <figure class="mT30"><img src="/eng/products/abd/img/oxycapt_p09_pc.png" alt="Graph and photo: Inorganics extractables of OXYCAPT" width="725" height="359"></figure> <p class="textS mT5"><Test method></p> <ul class="textS"> <li>- Filled with 10mL Water</li> <li>- Stored for 1 Month（25℃/60%RH）</li> <li>- Analysis; ICP</li> </ul> </div> </section> <section> <h2 id="ac05" class="ttl-h2 alignC sp-alignL">Product Portfolio</h2> <div class="boxContentsS"> <div class="sp-table-scroll mT1L"> <table class="table-data hAuto"> <thead class="alignC"> <tr> <th scope="col">ISO<br>Vial</th> <th class="w15" scope="col">Height<br>(㎜)</th> <th class="w15" scope="col">OD of Body<br>(㎜)</th> <th class="w15" scope="col">OD of Crown<br>(㎜)</th> <th class="w15" scope="col">ID of Crown<br>(㎜)</th> <th class="w25" scope="col">Packaging Option</th> </tr> </thead> <tbody class="alignC"> <tr> <th scope="row">2R (2mL)</th> <td>35</td> <td>16</td> <td>13</td> <td>7</td> <td>Tray or Nest/Tub</td> </tr> <tr> <th scope="row">6R (6mL)</th> <td>40</td> <td>22</td> <td>20</td> <td>12.6</td> <td>Tray or Nest/Tub</td> </tr> <tr> <th scope="row">10R (10mL)</th> <td>45</td> <td>24</td> <td>20</td> <td>12.6</td> <td>Tray or Nest/Tub</td> </tr> <tr> <th scope="row">20R (20mL)</th> <td>55</td> <td>30</td> <td>20</td> <td>12.6</td> <td>Tray or Nest/Tub</td> </tr> </tbody> </table> </div> <p class="textS">*The product is customizable. Please contact “Contact Form”.</p> <div class="clearfix mT30"> <div class="boxL alignC"> <figure><img src="/eng/products/abd/img/oxycapt_p10.jpg" alt="OXYCAPT" width="300" height=""></figure> </div> </div> </div> </section> <section><section> <div class="productsInquiry_btn"> <a href="/eng/inquiry/products/?pname=New+medicine+container%EF%BC%88Product+Name%EF%BC%9AOXYCAPT%E2%84%A2%EF%BC%89&div=Research+%26+Development+Division%EF%BC%8FNew+Business+Development+Department">Inquiries Concerning<br class"sp-dsp-none"> Products</a> </div> </section> <section> <div class="box-colorD full-left-box contactArea"> <h2 class="ttl">Inquiries Concerning Products</h2> <p>Research & Development Division<br>New Business Development Department 　<br>TEL：+81-3-3283-4913</p> <p class="link-btn-normal red"> <a href="/eng/inquiry/products/?pname=New+medicine+container%EF%BC%88Product+Name%EF%BC%9AOXYCAPT%E2%84%A2%EF%BC%89&div=Research+%26+Development+Division%EF%BC%8FNew+Business+Development+Department"><span>Contact Form</span></a> </p> </div> </section></section> <section></section> <section> <div class="relatedArea"> <h2 class="ttl">Related products</h2> <ul class="col-3 sp-col-2 related-list"> <li><a href="/eng/products/ac/nmxd6/"> <span class="txt">Nylon-MXD6</span> <span class="img"><img src="/eng/products/abd/img/oxycapt_bnr01.jpg" alt=""></span> </a></li> <li><a href="/eng/products/sc/pharmakeep/"> <span class="txt">PharmaKeep™<br class="spS-dsp-none">(for pharmaceuticals/<br>medical equipment)</span> <span class="img"><img src="/eng/products/abd/img/oxycapt_bnr03.jpg" alt=""></span> </a></li> </ul> </div> </section> </div> </div>  </main> <footer id="footer"> <div id="footerArea">  <div class="contentsInner ftrInner"> <div id="ftrMenu-block" class="col-2 col-clm1-2"> <div id="ftr-logo"> <a href="/eng/"><img src="/eng/shared/img/ftr-logo.svg" alt="MGC Group logo"></a> <ul class="ftr-sns"> <li><a href="https://www.youtube.com/channel/UCRVaVQrnl8KbJD1hafPJ2ag" target="_blank"><img src="/eng/shared/img/youtube_icon.png" alt="youtube logo"></a></li> </ul> </div> <div id="ftrSubMenu"> <ul> <li><a href="/eng/sitemap.html">Sitemap</a></li> <li><a href="/eng/privacy/">Privacy Policy</a></li> <li><a href="/eng/sns_policy.html">MGC’s Social Media Policy</a></li> </ul> <ul> <li><a href="/eng/site.html">Terms of Use</a></li> <li><a href="/eng/accessibility.html">Web Accessibility Policy</a></li> </ul> </div> </div> </div>  <div id="ftr-copyright"><div class="contentsInner"><p>Copyright © MITSUBISHI GAS CHEMICAL COMPANY, INC. 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