CINXE.COM

Just a moment...

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="390"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "www.int-res.com",cType: 'managed',cRay: '92b2228b2c5fcf50',cH: '2Cqko1ah6NjLzzl8xp.SDfkqX.7Oxt5RI9p_CSPPzko-1743783645-1.2.1.1-4hpMxiQkk_5jZY76TWfJQWvwL4S65hMvb3y21GING.vu1UttSkm2pYOqb.9Af1gD',cUPMDTk: "\/abstracts\/ame\/v39\/n3\/p293-302\/?__cf_chl_tk=oPxYvzE.OLeOZ.wL5f424Jzl_kIala0W9PSSTfDh_hw-1743783645-1.0.1.1-OhEREsRJ.pEqTMSnyKpnHJ170mFYHUTrcXNylurxhy0",cFPWv: 'g',cITimeS: '1743783645',cTTimeMs: '1000',cMTimeMs: '390000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/abstracts\/ame\/v39\/n3\/p293-302\/?__cf_chl_f_tk=oPxYvzE.OLeOZ.wL5f424Jzl_kIala0W9PSSTfDh_hw-1743783645-1.0.1.1-OhEREsRJ.pEqTMSnyKpnHJ170mFYHUTrcXNylurxhy0",md: "dKkxSYT4lZ8bDR2GcekAkXYyMeFyZ_psKrvyISPfiVU-1743783645-1.2.1.1-PTsoBTgyC60GYyAm6NvWKumZnBuYPYx2AonvwrdJLInLdPgZBHbpOAeKT3ThV3jM.utvxyg5q7sRGlUKAxSl.5vrllDdQ3sVab4eq5iEk4CYYMFBIGmF6W3DRrcwWZ3YkcvtAj_igVij1UpTYMceb2uPJeVVOJ4dK5bKW3KtdzP_iTzXk1haFL3XsW1._rU7bWnbRdpKQPclDB4iCANud5OlJ8cF0XoIs68wsg2uyohwYbi9MwWxUNzDkgjp4CfzXkVMoj5WJCEpmgALc681MCgmaoanzMp47O23b85Z3SgpvGpRPRks_DDEtQxWVE4j9FbCiF6a2yBdIkRipLRvxyxhqYDKXsr5fCdGGLjf9dKQLjLL.ZcT4qSj9m57A3tcJvK_2QbgUxu1Y08MQahlV1.MARKxEU.q2HmqL0gICPvyX81vwUztjwkNp2NDB_8X027xTYlHkyQpPsHurjr.TXESYmevT8v8Jwu5h9dL6BG6n7yeJoZcZuaPuTxHZsrza0.kx0YZEC.QH00KzOOihivvLPVqcpoMNDjbZilMWi0PPWAcdTDOd4vjvHto5yzL95EeU5RFTkUb7Vp79P3TthAqjFfiKmojYHQpeO_IYTNpQnDAsS.rHzGynewrFL966nmqV0to.fYHrJTfPCvUVWzDZH_epVEqIbItZH4esoxGELhF0KMIBnvG08ElOpeLJh_WBfBoSR5nMDehw0WPPmSIPmTd0FPvg_yCoeB6RUaeswfxcX4NYkSwHcAcPas3hrjweBJXGf96x2AQRiz9zxbR4cYYUKGoFx0TjRg7u0Af7XmE0vFV1re3lWjwdISZdvNp9huqRozAdAJT0anWhF77cN0PWHSLH87qf1fp5iRvy6vWoM_nqzfTqXn7n98xP5HcN68COyKejm0cf3RBG11BcU14PNn1Nnr6SRJzJxC2ELO7EkwXB8jIfoPxd7pXaDNU2NbYmbwtMBvZ6JebrF67uYgdN83BV_LjSkh9jWDyVqz8X50WyB7JaJQSIRmD7Pey4Z6KRbo3ZJ3P883a8Ulnikmy6PgxbHeTqCZ7MY725w4qMXh_HQViDpEA.fGHpIAKcGZnfTP.C6XEfsRSfAEdAWIpwUJOpt9ZjSZFnuSc0mI62ar30r88waBeYhJ4",mdrd: "T5RDsQmgYJgT6ooBop7OlMXOJsTrl_BCGWCQMaaMugc-1743783645-1.2.1.1-vsCEgfFJ38uX5e0FnTddzQ_dfx5YENj1U4LJs_8GSeXmPb3ThbbmfRbwd5faGrG7.1RFVtTl8KhF..SJ69wVWj7q45vZ5aphf6lGXqWuH53EVty5xP9JQySBg3Ift76UPSDcxcxASPaqDPq6nwFs7.j9MK93S0jGpTMimhREHBtxFwor5UM0EJdEqsPTPy7v0WRuzGx0Uq2.9dAgOAr.lEXNjGj0X6kmJ7MEHlhKgerXYxNSAriXm22xkpVu4eQ.lpvf4TP0ZLkXTKPW0gOlDZ4VwdJ2xJBnlpTwCFQpTa_5cpnlquIy8FP2EL4iAIUJecWQjF7uXo7_uwKMFWdG_bWZHzghZDXqD0tYacGj9JGh_YmcrPjPeQwfv_mtx_wUcanffb39yzAN.3AiRuwxIDBkOKOtnDcwKFQAXMroHsnFBOygR6VRHKmMRAyxNimjJ5TKGp4SlnCQmo6L9JeWzpmRTBYBbnnqQdKJ60uiOOVlWmRqo6mbOg05p4WG3hPNPS8VNrtK6bkIqsNpZMdgonR3MtyFLJTbglEUc15QDSqQbx.rGt4.LSL4H5YPNQZrbhIsMcNjdhkZWOHEYQSVi3dEozH8jeGEkPDMQrl_RR.CZcduK50iZz3E5ZKsEoNWL8YbcxKR6PNQhDI6wKdIf5H98oxVbXGqqLG68fBu89QEahvhpX3K.rbxUWrTN_sdzV_kvQZeH_tX239cjvbU8F6MIoiV1y0ktzAxSLag38sJnXMU6q3cumEdJKYF8Uwk4MHta3kDHbAY8Xi0TphL8KLK8s5XgHUUDtGUzmxwjcWr1UFKnQDkT6sGlvu9rcSUBKGsKLke.CRUhE3g1DlRu0xg5qobZA.r433H1My4N0vlp9lnnbTLMj9jRmzV0CfwVYk0sLr4zF_muvQPmSpe24OJI3lwxLLbqfvfG0NOb6_E8JBe.U4gD0fktrdrjYJRNtOjDTW7xNVAbOKTlwPIY1MXOS6tPkiz0CqT.FSin2vHfrcOccuCx3q3eeyT.qGBYrm2v2U2aXmTjpRHSSBy8tpw_hfJVw3mXvBjCJ7.sye24uUnmB5_EqaqUXO21a5PPBqFgz49p7dX6DUSbp5aG9MTuupCazKkAfDNqc3t1o7L8xgbx5qyDl0piZYryRnG4J0pF2MgP_Nlcvev2qkMcX9.bSP9a..POmyXc_ljggnNmEy.jwaaIm2ckGPgohMwKUIhGya.4WCSC2Yw1ExgItbDQCzLiMbYib4cuHmC8qkV1BeQxHY0dMNIyhJ1JsfCnRbLgPnZLYkv1_qamowC9PW0gaXgg4m6nYZY.u38uwJ.JeIwQUrWNxID.sLKVNh4Dh84vo.dsm5PUMk__58pUfEsleDSYQ76Kq3D.bEMNm2L9YD2cYMF_B50D_HMc7txllkemSwU_u1uWgl12trJuSWHIlhNc82puH12Wn1RuroHrOf2SzmZzJ4sLbE6Fzw2aVAVjeMsReIfXgEoh8aZz8IqLCNYeZbGWSL5yZgQyT6Q7Zm28.EQiqREtDYtTTvVZDnfVsZDJthwXg9glMKgBNGI1nh3z9.sSboHLVbNFUVzheboJLX2aaAr13gQjk4mTdtexBAgw9CjeZtXYGATPsav5.JHkEtUYyehmmAVsiH9625nSMDDkIsovKJXp6b1EXYutnl0LBEialzyEQ6e1n.3lakRWFzziwwswajb.peNWJEz0K2oaWUoj9ZLNGeLa.SYdYmP0T4_UTjRfUK_mKTSfJ_MFhyNKYLY6MmCbxO_YpI6Ity3fpqiU3FekppMulkT7lWWyNeQ8lv9yLtobeEa64VNZUPzGrP5aaJIJX0wy6bUYICRbZp02JHqjpnXstiOi.B0DBugEfeIHuW4i2zzp.Io.wBsHDuiJAjS6cgP9um8WjbPD19zKraZJi0wxJ6knfUVxr1mtE1SIwRdMZZXzECqYXY5NP9l3fLl0vILxvFuek_E85SXNjuRJb97Suowrkdv2UkKMohdNuBm.EMqojd6TmS7CGsHcTGCbrcg621boxMSd31eNM24czdsxljm3T6V4iQ8l7WewHHkCQ"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=92b2228b2c5fcf50';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/abstracts\/ame\/v39\/n3\/p293-302\/?__cf_chl_rt_tk=oPxYvzE.OLeOZ.wL5f424Jzl_kIala0W9PSSTfDh_hw-1743783645-1.0.1.1-OhEREsRJ.pEqTMSnyKpnHJ170mFYHUTrcXNylurxhy0" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>