Neoadjuvant Chemotherapy and Immunotherapy in Metaplastic Br

<!doctype html> <html lang="en"> <head>  <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"> <meta name="google-site-verification" content="IACPFCyYP-SMiV4khyHgqu1j88X5StL99Hd2ePFTlkg" /> <meta property="og:title" content="International Online Medical Council (IOMC)"> <meta property="og:site_name" content="International Online Medical Council"> <meta property="og:url" content="https://www.iomcworld.org/"> <meta property="og:description" content="International Online Medical Council journals provide an efficacious channel for researchers, students, and faculty members to publish works while maintaining excellence in medical research."> <meta property="og:type" content="article"> <meta property="og:image" content="https://www.iomcworld.org/assets/img/IOMC-logo.png"> <meta name="twitter:card" content="summary"> <meta name="twitter:site" content="@iomc8"> <meta name="twitter:title" content="International Online Medical Council"> <meta name="twitter:description" content="International Online Medical Council journals provide an efficacious channel for researchers, students, and faculty members to publish works while maintaining excellence in medical research."> <meta name="twitter:image" content="https://www.iomcworld.org/assets/img/IOMC-logo.png">  <link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.4.1/css/bootstrap.min.css">  <link rel="stylesheet" href="https://use.typekit.net/lpc2eiw.css"> <link rel="canonical" href="https://www.iomcworld.org/abstract/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report-110394.html"> <link rel="alternate" href="https://www.iomcworld.org/abstract/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report-110394.html" hreflang="en-us"/> <link href="https://fonts.googleapis.com/css?family=Spectral:200,200i,300,300i,400,400i,500,500i,600,600i,700,700i,800,800i" rel="stylesheet"> <link href="https://fonts.googleapis.com/css?family=Open+Sans:300,300i,400,400i,600,600i,700,700i,800,800i|Raleway:100,100i,200,200i,300,300i,400,400i,500,500i,600,600i,700,700i,800,800i,900,900i" rel="stylesheet"> <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.11.2/css/all.min.css" /> <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/4.7.0/css/font-awesome.min.css">   <link rel="stylesheet" href="/assets/css/jquery.mCustomScrollbar.min.css"> <link href="/assets/css/iconsmind.css" rel="stylesheet"> <link href="/assets/css/metisMenu.min.css" rel="stylesheet"> <link href="/assets/css/mm-vertical-hover.css" rel="stylesheet"> <link rel="stylesheet" href="/assets/css/coolautosuggest.css"> <link rel="stylesheet" href="/assets/css/global.css"> <link rel="stylesheet" href="/assets/css/styles-journals.css">  <link href="/assets/css/main_global.css" rel="stylesheet"> <link rel="stylesheet" href="/assets/css/styles.css"> <link rel="stylesheet" href="/assets/css/author.css">   <script async src="https://www.googletagmanager.com/gtag/js?id=G-ENVBW9JCFM"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-ENVBW9JCFM'); </script>  <div id="target" style="position: absolute; top: 110px;"> <div><p>GET THE APP</p></div> <a href="https://play.google.com/store/apps/details?id=com.journals.iomcworld&hl=en" target="_blank" id="getAppModel"> <div class="a_icon"> <span><i class="fa fa-android"></i></span> </div> </a>  </div>  <script type="application/ld+json"> { "@context": "https://schema.org", "@type": "Organization", "url": "https://www.iomcworld.org/", "logo": "https://www.iomcworld.org/assets/img/IOMC-logo.png" } </script> <script> !function(f,b,e,v,n,t,s){if(f.fbq)return;n=f.fbq=function(){n.callMethod? n.callMethod.apply(n,arguments):n.queue.push(arguments)};if(!f._fbq)f._fbq=n; n.push=n;n.loaded=!0;n.version='2.0';n.queue=[];t=b.createElement(e);t.async=!0; t.src=v;s=b.getElementsByTagName(e)[0];s.parentNode.insertBefore(t,s)}(window, document,'script','//connect.facebook.net/en_US/fbevents.js'); fbq('init', '297919997051754'); fbq('track', "PageView"); </script> <title>Neoadjuvant Chemotherapy and Immunotherapy in Metaplastic Br | 110394</title> <meta name="keywords" content="Jennifer Hammer*, Fr閐閞ique Dessy, Fran鏾is P. Duhoux, Micha雔 Hepp, Filomena Mazzeo, Latifa Fellah, Alex Fortun and Martine Berli鑢e, Metaplastic Breast Cancer (MpBC), Oncoplasty, Immunotherapy by checkpoint inhibitors"/> <meta name="description" content="Metaplastic Breast Cancer (MpBC) is a rare and complex entity accounting for approximately 0.2% to 5% of all breast cancers. We present here a case of MpBC..110394"/> <meta name="citation_publisher" content="International Online Medical Council" /> <meta name="citation_journal_title" content="Oncology & Cancer Case Reports"> <meta name="citation_title" content="Neoadjuvant Chemotherapy and Immunotherapy in Metaplastic Breast Cancer: A Case Report"> <meta name="citation_author" content="Jennifer Hammer" /> <meta name="citation_author" content="Fr閐閞ique Dessy" /> <meta name="citation_author" content="Fran鏾is P. Duhoux" /> <meta name="citation_author" content="Micha雔 Hepp" /> <meta name="citation_author" content="Filomena Mazzeo" /> <meta name="citation_author" content="Latifa Fellah" /> <meta name="citation_author" content="Alex Fortun" /> <meta name="citation_author" content="Martine Berli鑢e" /> <meta name="citation_year" content="2024"> <meta name="citation_volume" content="10"> <meta name="citation_issue" content="3"> <meta name="citation_issn" content="2471-8556"> <meta name="citation_publication_date" content="2024/07/25" /> <meta name="citation_firstpage" content="1"> <meta name="citation_lastpage" content="3"> <meta name="citation_abstract" content="Metaplastic Breast Cancer (MpBC) is a rare and complex entity accounting for approximately 0.2% to 5% of all breast cancers. We present here a case of MpBC in a 57-year-old woman who had a history of atrial fibrillation. Her lesion was classified cT3N0M0. She was treated with neoadjuvant chemotherapy associated with immunotherapy by checkpoint inhibitors. A good clinical and radiological response was observed, and the patient underwent right lumpectomy plus sentinel lymph node biopsy with oncoplasty and contralateral symmetrization. Histology confirmed a good response with a reduction in the size of the lesion and negative sentinel lymph nodes. The patient received radiotherapy and is currently in remission."> <meta name="citation_fulltext_html_url" content="https://www.iomcworld.org/open-access/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report-110394.html"> <meta name="citation_pdf_url" content="https://www.iomcworld.org/open-access/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report.pdf"> <meta name="citation_abstract_html_url" content="https://www.iomcworld.org/abstract/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report-110394.html"> </head> <body>  <header>  <div class="bg-1"> <div class="container-fluid py-1"> <div class="row justify-content-between align-items-center"> <div class="col-sm-auto"> <a href="https://www.iomcworld.org/" title="IOMC"><img src="/assets/img/IOMC-logo-white.svg" alt="occrs" height="50" alt="IOMC"></a> </div> <div class="col-sm-auto"> <nav class="nav"> <a class="nav-link white"><i class="fa fa-whatsapp"></i> + 44-1704335730 </a> <a href="mailto:editorial@journalres.com" class="nav-link white"><i class="fas fa-envelope-square"></i> editorial@journalres.com</a> <a href="https://www.scholarscentral.org/submissions/oncology-cancer-case-reports.html" title="Submit Manuscript" class="btn bg-yellow-100">Submit Manuscript</a> <div id="google_translate_element"></div> </nav> </div> </div> </div> </div>  <div class="py-3"> <div class="container-fluid"> <div class="row align-items-center justify-content-between"> <div class="col-12 col-sm-auto"> <h1 class="rockwell fweight-600 mb-0">Oncology & Cancer Case Reports</h1> <span class="float-right">ISSN - 2471-8556 </span> </div> </div> </div> </div>  <nav class="navbar navbar-expand-lg navbar-dark bg-1"> <a class="navbar-brand d-none" href="#">Navbar</a> <button class="navbar-toggler" type="button" data-toggle="collapse" data-target="#navbarJrnl" aria-controls="navbarJrnl" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-between" id="navbarJrnl"> <ul class="navbar-nav"> <li class="nav-item"> <a class="nav-link active" href="https://www.iomcworld.org/oncology-cancer-case-reports.html" title="Journal Home">Journal Home</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.iomcworld.org/oncology-cancer-case-reports/editorial-board.html" title="Editorial Board">Editorial Board</a> </li> <li class="nav-item dropdown"> <a class="nav-link custom-toggle" href="#" id="navbarDropdownMenuLink" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">Author Guidelines <i class="fa fa-angle-down align-middle" aria-hidden="true"></i> </a>  <div class="dropdown-menu custom-dropdown" aria-labelledby="navbarDropdownMenuLink"> <a class="dropdown-item" href="https://www.iomcworld.org/oncology-cancer-case-reports/aims-and-scope.html">Aim & Scope</a> <a class="dropdown-item" href="https://www.iomcworld.org/oncology-cancer-case-reports/instructionsforauthors.html">Instruction For Authors</a> <a class="dropdown-item" href="https://www.iomcworld.org/oncology-cancer-case-reports/guidelines.html">Author Guidelines</a> <a class="dropdown-item" href="https://www.iomcworld.org/oncology-cancer-case-reports/peer-review-process.html">Peer Review Process</a> <a class="dropdown-item" href="https://www.iomcworld.org/oncology-cancer-case-reports/ethical-malpractices.html">Publication Ethics & Malpractice Statement</a> </div> </li> <li class="nav-item"> <a class="nav-link" href="https://www.iomcworld.org/oncology-cancer-case-reports/inpress.html" title="Articles in process">Articles in process</a> </li>  <li class="nav-item"> <a class="nav-link" href="https://www.iomcworld.org/oncology-cancer-case-reports/archive.html" title="Archive">Archive</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.iomcworld.org/oncology-cancer-case-reports/submit-manuscript.html" title="Submit Manuscript">Submit Manuscript</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.iomcworld.org/oncology-cancer-case-reports/contact.html" title="Journal Contact">Journal Contact</a> </li> </ul>  </div> </nav>   </header> <script type="text/javascript"> function googleTranslateElementInit() { new google.translate.TranslateElement({pageLanguage: 'en'}, 'google_translate_element'); } </script> <script type="text/javascript" src="//translate.google.com/translate_a/element.js?cb=googleTranslateElementInit"></script>  <section class="py-5"> <div class="container-fluid"> <div class="row"> <div class="col"> <div class="card"> <h2 class="card-header">Abstract</h2> <div class="card-body p-2"> <h3>Neoadjuvant Chemotherapy and Immunotherapy in Metaplastic Breast Cancer: A Case Report</h3> <p> <i class="fas fa-user"></i> <a href='https://www.iomcworld.org/author/jennifer-hammer-73053' style='color:#555; border-bottom:1px dotted #CCC;' title='Jennifer Hammer'>Jennifer Hammer</a>*, <a href='https://www.iomcworld.org/author/freacutedeacuterique-dessy-73054' style='color:#555; border-bottom:1px dotted #CCC;' title='Frédérique Dessy'>Frédérique Dessy</a>, <a href='https://www.iomcworld.org/author/franccedilois-p-duhoux-73055' style='color:#555; border-bottom:1px dotted #CCC;' title='François P. Duhoux'>François P. Duhoux</a>, <a href='https://www.iomcworld.org/author/michaeumll-hepp-73056' style='color:#555; border-bottom:1px dotted #CCC;' title='Michaël Hepp'>Michaël Hepp</a>, <a href='https://www.iomcworld.org/author/filomena-mazzeo-73057' style='color:#555; border-bottom:1px dotted #CCC;' title='Filomena Mazzeo'>Filomena Mazzeo</a>, <a href='https://www.iomcworld.org/author/latifa-fellah-73058' style='color:#555; border-bottom:1px dotted #CCC;' title='Latifa Fellah'>Latifa Fellah</a>, <a href='https://www.iomcworld.org/author/alex-fortun-73059' style='color:#555; border-bottom:1px dotted #CCC;' title='Alex Fortun'>Alex Fortun</a> and <a href='https://www.iomcworld.org/author/martine-berliegravere-73060' style='color:#555; border-bottom:1px dotted #CCC;' title='Martine Berlière'>Martine Berlière</a> </p> <p> <p>Metaplastic Breast Cancer (MpBC) is a rare and complex entity accounting for approximately 0.2% to 5% of all breast cancers. We present here a case of MpBC in a 57-year-old woman who had a history of atrial fibrillation. Her lesion was classified cT3N0M0. She was treated with neoadjuvant chemotherapy associated with immunotherapy by checkpoint inhibitors. A good clinical and radiological response was observed, and the patient underwent right lumpectomy plus sentinel lymph node biopsy with oncoplasty and contralateral symmetrization. Histology confirmed a good response with a reduction in the size of the lesion and negative sentinel lymph nodes. The patient received radiotherapy and is currently in remission.</p> </p> <nav class="nav a-pl-0"> <a href="https://www.iomcworld.org/open-access/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report-110394.html" title="Click here" class="nav-link"><i class="fas fa-file-code text-success"></i> Full-Text</a> <a href="https://www.iomcworld.org/open-access/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report.pdf" title="Click here" class="nav-link"><i class="fas fa-file-pdf text-primary"></i> PDF</a> </nav> <div class="nav social-icons"> <a class="nav-link w-auto">Share this article</a> <a title="Click here" target="_blank" href="https://www.facebook.com/sharer.php?u=https://www.iomcworld.org/abstract/neoadjuvant-chemotherapy-and-immunotherapy-in-metaplastic-breast-cancer-a-case-report-110394.html"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="Click here" target="_blank" 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