Study on Phytochemical Properties, Antibacterial Activity and Cytotoxicity of Aloe vera L.

<!DOCTYPE html> <html lang="en" dir="ltr"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-P63WKM1TM1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-P63WKM1TM1'); </script>  <script type="text/javascript" > (function(m,e,t,r,i,k,a){m[i]=m[i]||function(){(m[i].a=m[i].a||[]).push(arguments)}; m[i].l=1*new Date(); for (var j = 0; j < document.scripts.length; j++) {if (document.scripts[j].src === r) { return; }} k=e.createElement(t),a=e.getElementsByTagName(t)[0],k.async=1,k.src=r,a.parentNode.insertBefore(k,a)}) (window, document, "script", "https://mc.yandex.ru/metrika/tag.js", "ym"); ym(55165297, "init", { clickmap:false, trackLinks:true, accurateTrackBounce:true, webvisor:false }); </script> <noscript><div><img src="https://mc.yandex.ru/watch/55165297" style="position:absolute; left:-9999px;" alt="" /></div></noscript>    <title>Study on Phytochemical Properties, Antibacterial Activity and Cytotoxicity of Aloe vera L.</title> <meta name="description" content="Study on Phytochemical Properties, Antibacterial Activity and Cytotoxicity of Aloe vera L."> <meta name="keywords" content="Aloe vera L., antimicrobial activity, brine shrimp,cytotoxicity, phytochemical properties."> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <meta name="citation_title" content="Study on Phytochemical Properties, Antibacterial Activity and Cytotoxicity of Aloe vera L."> <meta name="citation_author" content="K. Thu"> <meta name="citation_author" content="Yin Y. Mon"> <meta name="citation_author" content="Tin A. Khaing"> <meta name="citation_author" content="Ohn M. Tun"> <meta name="citation_publication_date" content="2013/05/28"> <meta name="citation_journal_title" content="International Journal of Biotechnology and Bioengineering"> <meta name="citation_volume" content="7"> <meta name="citation_issue" content="5"> <meta name="citation_firstpage" content="285"> <meta name="citation_lastpage" content="289"> <meta name="citation_pdf_url" content="https://publications.waset.org/5207/pdf"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="" name="q" aria-label="Search"> <button class="btn btn-light my-2 my-sm-0" type="submit"><i class="fas fa-search"></i></button> </form> </div> <div class="collapse navbar-collapse mt-1" id="navbarMenu"> <ul class="navbar-nav ml-auto align-items-center" id="mainNavMenu"> <li class="nav-item"> <a class="nav-link" href="https://waset.org/conferences" title="Conferences in 2024/2025/2026">Conferences</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/disciplines" title="Disciplines">Disciplines</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/committees" rel="nofollow">Committees</a> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdownPublications" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"> Publications </a> <div class="dropdown-menu" aria-labelledby="navbarDropdownPublications"> <a class="dropdown-item" href="https://publications.waset.org/abstracts">Abstracts</a> <a class="dropdown-item" href="https://publications.waset.org">Periodicals</a> <a class="dropdown-item" href="https://publications.waset.org/archive">Archive</a> </div> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/page/support" title="Support">Support</a> </li> </ul> </div> </div> </nav> </div> </header> <main> <div class="container mt-4"> <div class="row"> <div class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value=""> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 33100</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Study on Phytochemical Properties, Antibacterial Activity and Cytotoxicity of Aloe vera L.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/search?q=K.%20Thu">K. Thu</a>, <a href="https://publications.waset.org/search?q=Yin%20Y.%20Mon"> Yin Y. Mon</a>, <a href="https://publications.waset.org/search?q=Tin%20A.%20Khaing"> Tin A. Khaing</a>, <a href="https://publications.waset.org/search?q=Ohn%20M.%20Tun"> Ohn M. Tun</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the study was to investigate phytochemical properties, antimicrobial activity and cytotoxicity of Aloe vera. The phytochemical screening of the extracts of leaves of A. vera revealed the presence of bioactive compounds such as alkaloids, tannins, flavonoids phenolic compounds, and etc. with absence of cyanogenic glycosides. Three different solvents such as methanol, ethanol and Di-Methyl sulfoxide were used to screen the antimicrobial activity of A. vera leaves against four human clinical pathogens by agar well diffusion method. The maximum antibacterial activities were observed in methanol extract followed by ethanol and Di-Methyl sulfoxide. It was also found that remarkable antibacterial activities with methanolic and ethanolic extracts of A. vera compared with the standard antibiotic, tetracycline that was not active against E. coli and S. boydii and supported the view that A. vera is a potent antimicrobial agent compared with the conventional antibiotic. Moreover, the brine shrimps (Artemia salina) toxicity test exhibited LC50 value was 569.52 ppm. The resulting data indicated that the A. vera plant have less toxic effects on brine shrimp. Hence, it is signified that Aloe vera plant extract is safe to be used as an antimicrobial agent. <iframe src="https://publications.waset.org/5207.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=Aloe%20vera%20L." title="Aloe vera L.">Aloe vera L.</a>, <a href="https://publications.waset.org/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a>, <a href="https://publications.waset.org/search?q=brine%20shrimp" title=" brine shrimp"> brine shrimp</a>, <a href="https://publications.waset.org/search?q=cytotoxicity" title="cytotoxicity">cytotoxicity</a>, <a href="https://publications.waset.org/search?q=phytochemical%20properties." title=" phytochemical properties."> phytochemical properties.</a> </p> <p class="card-text"><strong>Digital Object Identifier (DOI):</strong> <a href="https://doi.org/10.5281/zenodo.1060625" target="_blank">doi.org/10.5281/zenodo.1060625</a> </p> <a href="https://publications.waset.org/5207/study-on-phytochemical-properties-antibacterial-activity-and-cytotoxicity-of-aloe-vera-l" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/5207/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/5207/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/5207/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/5207/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/5207/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/5207/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/5207/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/5207/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/5207/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/5207/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/5207.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">6051</span> </span> <p class="card-text"><strong>References:</strong></p> <br>[1] H. R. Davis, Aloe vera: A Scientific Approach. Vantage Press, New York, SA, 1997. <br>[2] B. C. Coats, The Silent Healer, A modern study of Aloe vera. Texas, Garland. 1979. <br>[3] M. Obata, "Mechanisms of anti-inflammatory and anti thermal burn action of carboxypeptidase from aloe aborescens miller" Natalensis berger in rats and mice physiotherapy research, vol. 7, Special issues, pp. 530-533, 1993. <br>[4] M. S. Shelton, "Aloe vera, its chemical and therapeutic properties," International Journal of Dermatology, vol. 30, pp. 679-683, 1991. <br>[5] P. Green, "Aloe vera extracts in equine clinical practice," Veterinary Times, vol. 26, pp. 9, 1996. <br>[6] J. B. Kahlon, "Inhibition of Aids Virus replication by Ale Mannan in vitro," Molecular Biothermy, vol. 3, pp. 127-135, 1991. <br>[7] M. A. Sheets, "Studies of the effect of ace Mannon on retrovirus infections, clinical stabilization of feline leukemia virus infected eats," Molecular Biothermy, vol. 3, pp. 41-45, 1991. <br>[8] L. J. Lorenzetti, R. Salisburry, J. L. Beal and J. N. Baldwin, "Bacteriostatic property of Aloe vera," J. of the Pharm. Sci., vol.53, pp. 1287-1290, 1964. <br>[9] P. Sims, M. Ruth and E.R. Zimmerman, "Effect of Aloe vera on Herpes simplex and herpes virus (Strain Zoster)," Aloe vera of American Archives, vol. 1, pp. 239-240, 1971. <br>[10] T. Hirat and T. Suga, "The efficiency of aloe plants, chemical constituents and biological activities," Cosmetics and toiletries, vol. 98, pp. 105-108, 1983. <br>[11] B. C. Coats, The Silent Healer, A modern study of Aloe vera. Texas, Garland. 1979. <br>[12] K. H. Lee and J. H. Kim, "Anti-lukaemic and anti -mutagenic effects of di (2-ethylhexyl) phthalate isolated from Aloe vera Linn.," Journal of Pharmacy and Pharmacology, vol. 52, no. 5, pp. 593-598, 2000. <br>[13] K. M. Abdullah, A. Abdullah, M. L. Johnson, J. J. Bilski, K. Petry, D. A. Redmer, L. P. Reynolds, A. T. Grazul-Bilska, "Effects of Aloe vera on gap junctional intercellular communication and proliferation of human diabetic and non-diabetic skin fibroblasts," J. Altern. Complement. Med., vol. 9, no. 5, pp. 711-718, 2003. <br>[14] M. S. Shelton, "Aloe vera, its chemical and therapeutic properties," International Journal of Dermatology, vol. 30, pp. 679-683, 1991. <br>[15] K. Fujita, Y. Yamada, K. Azuma and S. Hirozawa, "Effect of leaf extracts of Aloe arborescens subsp. natalensis on growth of Trichophyton metagrophytes," Antimicrobial agents and chemotherapy, vol. 14, pp. 132-136, 1978. <br>[16] M. L. Dhar, M. M. Dhar, B. N. Dhawab, American Botanical Journal, pp. 232, 1968. <br>[17] A. Sofowara, Medicinal plants and Traditional medicine in Africa, Spectrum Books Ltd., Ibadan, Nigeria, pp. 289, 1993. <br>[18] J. B. Harborne, Phytochemcial methods, London, Chapman and Hall Ltd., pp. 49- 188, 1973. <br>[19] O. O. Agarry, M. T. Olaleye and C. O. Bello-Michael, "Comparative antimicrobial activities of Aloe vera gel and leaf," African journal of Biotechnology, vol. 4, no. 12, pp. 1413-1414, Dec. 2005. <br>[20] B. N. Meyer, N. R. Ferrign, J. E. Putnan, L. B. Jacobsca, D. E. Michols, and J. L. Molaughlin, Brine Shrimp, A Convenient General Bioassay for Active Plant Constituents, 1982. <br>[21] E. Simionatto, C. Porto, U. F. da Silva, A. M. C. Squizani, I. I. Dalcol, A. F. Morel, J. Braz. Chem. Soc., vol. 16, pp. 1458-1462, 2005. </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); });*/ jQuery.get({ url: "https://publications.waset.org/xhr/user-menu", cache: false }).then(function(response){ jQuery('#mainNavMenu').append(response); }); }); </script> </body> </html>

CINXE.COM

Study on Phytochemical Properties, Antibacterial Activity and Cytotoxicity of Aloe vera L.