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KEGG PATHWAY: Phosphonate and phosphinate metabolism - Reference pathway

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C-P compounds have been found in many organisms, but only protists and bacteria, mostly Actinobacteria, have biosynthetic capacity. A common reaction in the biosynthetic pathway is C-P bond forming reaction from phosphoenolpyruvate (PEP) to phosphonopyruvate (PnPy) catalyzed by PEP phosphomutase. 2-Aminoethylphosphonate (AEP) is the most abundant C-P compound in the natural world. AEP derivatives include phosphonoprotein, phosphonoglycan, and phosphonolipid. Other known C-P compounds are bioactive substances used in medicine (antibiotics) and agriculture (herbicide) such as fosfomycin, FR-33289, rhizocticin, and bialaphos. </div> <!-- organism list start --> <form name="selmenu" method="get"> <input type="button" id="changePathwayTypeButton" value="Change pathway type"> <input type="text" class="hidden" name="mapno" value="00440" /> <input type="text" class="hidden" id="scale" name="scale" value="1" /> <input type="text" class="hidden" id="displayNoColoringImage" name="nocolor" value="0" /> <input type="text" class="hidden" id="displayDescription" name="show_description" value="hide" /> <input type="text" class="hidden" id="displayControlPanel" name="show_module_list" value="show" /> <input type="text" class="hidden" id="clickableMode" name="clickable_mode" value="" /> <input type="text" class="hidden" name="module" value="" /> </form> <!-- organism list end --> </div> <!-- page navigation end --> <!-- pathway image start --> <div 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name="content" /> <input type="hidden" name="dpi" /> <input type="hidden" name="decode" value="base64" /> </form> <div id="waiting-circle"> <img src="/Fig/waiting-circle-small.gif"> </div> <!-- pathway image url start --> <form class="imageset" data-name=""> <input type="hidden" name="image_normal" value="/kegg/pathway/map/map00440.png 1x" data-src="/kegg/pathway/map/map00440.png" data-situation="1x"> <input type="hidden" name="image_grayscale" value="/kegg/pathway/map/map00440.png 1x" data-src="/kegg/pathway/map/map00440.png" data-situation="1x"> <input type="hidden" name="image_grayscale" value="/kegg/pathway/map/map00440@2x.png 2x" data-src="/kegg/pathway/map/map00440@2x.png" data-situation="2x"> </form> <!-- pathway image url end --> <div id="download-menu" style="display:none;"> <div><a class="downloadImageNx" data-scale="1" href="#downloadImage1x">Image (png) file 1x</a></div> <div><a class="downloadImageNx" data-scale="2" href="#downloadImage2x">Image (png) file 2x</a></div> </div> </body> </html>

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