CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="120"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "publications.waset.org",cType: 'non-interactive',cRay: '91361d4c7ea98819',cH: 'jyBiGV5PAluhZk3FXgLkPBbfMXxlPi_69a3e9UgNssU-1739798842-1.2.1.1-vvF51BUBW9gTp1mW0CIWlPfjQ46.B9FFtTjUDN3DHpL8VDg3PD9ebNubV0MNyqlP',cUPMDTk: "\/abstracts\/search?q=randomized%20clinical%20trials&__cf_chl_tk=BdHadub4mTuhFnO8coJyfW45ZsuhMkMm0yQGIR8wZ68-1739798842-1.0.1.1-a1B.AGpxy3t8iSvmcnKsPeuIZPYlv8rNV5lBrjU95RU",cFPWv: 'g',cITimeS: '1739798842',cTTimeMs: '1000',cMTimeMs: '120000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/abstracts\/search?q=randomized%20clinical%20trials&__cf_chl_f_tk=BdHadub4mTuhFnO8coJyfW45ZsuhMkMm0yQGIR8wZ68-1739798842-1.0.1.1-a1B.AGpxy3t8iSvmcnKsPeuIZPYlv8rNV5lBrjU95RU",md: "Ey_Q.D9BeUlpyTGnvXXqmvED4m4mCwqX1.MPyHbBMGU-1739798842-1.2.1.1-AVvtfMlRnedn8agY5JmaQdUDt4zVRvv4PCZvm6tRJbb_bIvk.LJo_cTgxvTC9S5hf.Tw4tq_L_0C_2OmJ6rx_nWj3OIwN1AKF5m4gYVDmEXBq3pHlyZrpNhzEeVzibbVY7GhvKBuuq1JQsZApdEDD6KO5WYUeNbJd7HQkPHv45wMKj59UJKpxZI_JjWBs.kYoutuCSbiFra77gkpYxU02BmNrPUeIPgoFXdQwp82lBGzXd1gg3IlUZ6QZpdP6ffRjYnBkOxH1jGar_QYhXiDo9YCmOmdDImag3KIvY98RnJkoVYGAAyQvARGpTn5guD7_jf56xKtwxFZANaVVgsnLr5E0F4fj4vbM.nyfFSDKcDyZcsx81hk7.XC1.cyAjTQzYIXxXJ8ijns1zyWuBlLDttPNTy0rHFsHk6jvJfCjFbRZqCo85zDQp.Iofhhc7y511iW.fFw3subrAwJSIRe8s6u47Tiqtx.hL1.9EJ1sVi8Md13boGBvxuqCGrpQRrn07grVOLSkiB.1gU63DPm7E7P45f5tCX1N9QorR..McxcYGpmUKNV96yOz92YgRl4CNjyKqMNXcyv6EEG8fFw3j9C0akiMQ_44Q4_qKoGn64I0cFzZXPUR5GSoO4R.GfmnpSYAxLr20kMb.rX.2u_qmP5wYgALnMcBUDMU7NmE45BJqLfD5LzCC2gtLnHYCekG02f.vb8a6at1a6uJrouH_UFsKjsYGdplU7bkE4qzD4gcg05tikdogk2LEsSDIequL7Hsl_WR7WgvJFZV6eQVxxnC.5PLWXvQscrLI4J.g_FFxIONnYq7te6PRAO9fPS6agwqUwMouo_AnUvSRSPc3XdXyEnwDIzivQm6QPz3Jno1ypy2duyeRHyAZFfXCoXn48SLpSojVaALG_SKvldiKNHOojj2ZuZhhG5fktIl46k1i7B2wL6JBEpzVQt4FXHfI71T0DC3ZK9fCU3bAuT2vfFB0zV4ypjDa7htFRLIlRDj1_cAQkPATyCLSeMxNctu1__iulM34eRFWtQUxD.5RrlPw4cX62juFml08fggdEKqgewJb292i8XWNmygJqUrEOcCksWUc6BQ1C2o4or1kbOWSAfq2VSD7H50poeyqYeQ5VsKKV4UjGWAkgbgEpwy3N27jttUBzCxLSPb2ere4ee8AbERalaSuT2dSNKjPjMCnDK2jnTyovhHCsfxCCsD0II9iboXo9LnAKSLHXrWBqYzxt8c5TaQtpgkGfvsXUKfZxj4DmttwEWLSZxQN6EmYtwNgajRxvM6eQsUNhj2xV81NX7FQSnYiVVRYG1bw2uPv_xIvWdSywox5z5y9uaSHAnm4QYDnQClQcHkIkUYN.R058HQFwyjFbArDY7DLbJTg1K87DHzpCtVNkNrR0LPNURe_nVXN4X.5lPxdWJ8wLWcnKgZqm8f0jJiG9JMVqU_AZLQ6dd1KQFPplwGM7FP8RnBybij.CgfIdtbTRdno0XeXSRqjI82tsFZvNYbJU8xNvHalFx74c.tnzmVJIkVNfHqNuHanStU1eGOXgr23UHWCESM4AzB.Mhp1XlK97IskljINBcrLzj8vRGZYwYn.wD_aEIgb.2XmimAIKzi6DFfxbzmsmXd4IXaZ20YbEglHO1KJ8odJQtYnHdmdKcrBQKWjKarApOvZbKtEJozNbbp.HKsdSrh6naTmhnaX3winWhFDsUWXhgfMEawMnD1KfSHCaLZIsCoS0qBS4s8onQaS2M6Alln7Z1lWdGtO96txI.HxtuRGtb8FbZ7b8FEJaV0vGA6QUqSkPZEFUCr5tHc2FgYIglKz2S0ZrB7jfK8D7MaGrGkLzu47sCU9DgnXFlRGgJ7PXbLgMyOe4ebFuK15DHL4Yu1ZBmZK_wB1S3TrA6B7LKVOLYlwmFqjkLRSqgtDEXxDIhREHwR_M3R.WVorMkyglWKLYMb5q5MwqoZxMt0Z4MuTaG2hELsZc0owut38PNP49cM.ZiNbrvCQ",mdrd: "AUNLbkvkR6sAACa9Dx5AY1zfK8Xn83fEiPODi1ZFWyQ-1739798842-1.2.1.1-Uf1cIBDjVJsOds92LCRgpcMPrYMN7Dn2JyKJvng9UI20UrUlqswOvsTkb3xOQg8VYPtXK_KCu8qjIKo1_28unAxsy6RPZOM0BSVN5fVkv7.RfMnhFEyDBbsY3JESZ7H4GsYxERxvMJiP7csYIa.UyNKtDFna5jHnLy8lemPNISXOGFJuBTTbO8onHJIiq3dJmsuBip61M0Mf_ALHNtS1NvD87JmxDQSUPcEpBYthF3ov87VSVzkdlumPGSFYt8z8rdCDtQNubKihuUs93F.Pp2Ks1uHSTGBx6sHLqq4VNNieYGZIfrxXZQO6UM8nSDvzzSgMth3QCHvm4IsUXAO2avIQgoIWwuqGY473g5JVfIrUnP8btAbQrCuNrMhCAHgTAHdy2K5Rr7VjCtXF_nD1.P7XYtn14pHgqu1.ZgeRbSoTM.FoqcExFJaO3vjUzeoElKEZ8nKyhI8G3qQouYkAV2f8qzgJNxYcCtc.dqcUTcYKngT6Bzf_AbOIopkFXfmfquu2S4qOeLFU91jo5E0a56PvJM7xL81TTi50a70nJSsm1EyzIq4uSa_BkHvlJ5i1Ns00qEtZmcgogMonHtqXZw6g9vpDXCxW9lqo.5n8B8d7l4G7rUbNbDbvZplR10NgEZ1MKbdkMxHFra3TN.YodgaR.hWIezh_PdKpcgLzS.F_vOvvXFKWfT_EcgVUo_9w54iGZCkl4GOkSQmtDDbmtX_3jaEU1.D_ierC8mhnen28.X9pKxPkatn7IlcA5TPoS62JdNO40pB671UPITGss6oKK3rlWBPZXd9Wqwcc7ygfe1P4SWJE0SGjbPO.bqFMXzGdyVLzQNU7GXc4EMHPAhhw24TAWQA3R9.WVUexdeLUS8dUiKoL8I2E5_9IZOigAy8XmIa0_XnSYIPeLkJ6PSK49OdZDbs5A6Or5VGcUnGYDU5Hd_8ujxg6yqP0Y1mrdnU2wzmKJlj2ZHnOdZmlix6W8dUJXPYFop2_TQo6KVQVmzR.LOsvhPiku2_MHHD.oLewsgMMPZt2uPTQwRfSu7bmcsX95VMY5.M1vqPf_urHLgeD5i9WHSZIdhBVz37BfIUu3wXJ.u20lsH.WfiJBQ1cOmiIU2QG54kw_u21BX2e7fc9jG89PmZ0GIoqMMvjJgS3WdBx6pFQOaPFHuVttvCsBRNzxqEo7_YITKeSWh7YLNpxztLDMSjM7dwM.RcfuV1j7D8V5M38h9gWr0MozW8VNalffa7RTiL5NAGND738NN.4192F8ezulP3x9ZJxF.bUBNJGEB7WGQ7_lRER9Edy3ihPtzk20kl5xLC5t.O074jvylHOzQrMMpA474Pj1I2nmQ0a1yQQEbYd7kmMmGq6vJ16q1XrVBKExA2Oc8X3XffCa7JDPgI98kbV36AFjcYeO5YK5hGeVJbL7INNqYCK72YpwnsH.MhD5LlWBGkKDIjw7tgrW4zA28pM2dTchFW.OkBNkuK8jo1s341O_h74xOpyaANxomrob02THuLJkA_4D5YpqViURACeDlE0gykYSq.PhvOhmxBNe5zkOyDROh93PLLBj7Z5EQcAH0IiE6iq8stQ6gMqGU4AxglpL8heGlwXhoN4YMrc2uwlCUtWjw__2Hd43Go77F0vWjrWUe_dnqnUBk7nMyTpRmOD386k7RdpHfXXPONnDM5SazPgkRyFHo6jy812s3vbmbkaMX_NJFUXtb1D.jkzBujaIWJpTaUclJ75S_ETeBRPmT0GNlu4nghDjgnobizsYTnuNqlIuJbtT3zfhuGHs9NCyWcBFFN0Uf3wTNpFZxOK4sA5WBheSYjfMoDtenw0KguE8ivBL22AYgwz.3tFnaTNLRFez0PhrFgHyWk_SoU34icLGhxqjqBe6C_posp_N_P6RiSwyXawLwx0phOSEx6fd.ZBkCA68H3fGtznSMUttSCzQ9f.AnYu1nbrxGmy66ROPh.GUkARcTp5v0MmewG8Aw1ZGrh5Ly7Smn2N27NOxw"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=91361d4c7ea98819';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/abstracts\/search?q=randomized%20clinical%20trials&__cf_chl_rt_tk=BdHadub4mTuhFnO8coJyfW45ZsuhMkMm0yQGIR8wZ68-1739798842-1.0.1.1-a1B.AGpxy3t8iSvmcnKsPeuIZPYlv8rNV5lBrjU95RU" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>